Duspatalin analogues of duspatalin, indications for use. List of Duspatalin analogues: available generics

Various digestive diseases and syndromes are often associated with severe cramps and pain in the intestines. Duspatalin quickly and effectively helps to cope with them, almost immediately after administration. But sometimes the specified drug has to be replaced due to addiction to it or lack of availability in the pharmacy. In addition, not all people tolerate Duspatalin well - analogues, fortunately, are represented by an extensive list of medications with identical effects and a more reasonable price.

What can replace Duspatalin?

This drug contains one active ingredient - mebeverine hydrochloride. It is a myotropic antispasmodic that has a direct effect on the smooth muscles of the intestine, relaxing it and relieving pain. In this case, the component does not affect peristalsis and does not lead to stool disorders.

The following chemical compounds are considered similar in their mechanism of action:

• trimebutine maleate;
• pinaverium bromide;
• hyoscine butyl bromide;
• Hymecromone.

There are quite a lot of products based on the above ingredients. Among them there are the following analogues of the drug Duspatalin in tablets:

• Trimedat;
• Dicetel;
• Buscopan;
• Odeston;
• Nyaspam;
• Trigan-D;
• Sparex;
• Mebeverine;
• Papaverine;
• Dibazol;
• Trigan;
• Spascuprel;
• Bendazole;
• Meverin;
• Drotaverine hydrochloride.

The first four names are considered the closest to Duspatalin in terms of the method and speed of action, moreover, they are cheaper than the drug described. Let's look at their properties in more detail.

Trimedat or Duspatalin - which is better?

Developed on the basis of trimebutine, Trimedat produces not only an antispasmodic, but also a regulatory effect. The drug helps accelerate gastric emptying and allows you to restore normal intestinal motility during both hyper- and hypokinetic conditions. pathological conditions. It quickly eliminates motility disorders and protects smooth muscles from food irritants.

In view of the listed properties, Trimedat can be called more effective medicine, with the help of which not only intestinal spasms are eliminated, but also its functional and dyspeptic disorders.

What helps better - Dicetel or Duspatalin?

Dicetel contains pinaverium bromide. Given chemical compound reduces the sensitivity of neurons and reduces the severity pain in the intestines, relieves spasms. In addition, the medication eliminates discomfort caused by functional disorders of not only the intestines, but also the biliary tract, and restores the transit of intestinal contents.

Dicetel, however, does not help with irritable bowel syndrome as well as Duspatalin, but with its help you can effectively treat the symptoms of gallbladder diseases.

Which is better - Duspatalin or Buscopan?

Hyoscine butyl bromide, the active ingredient in Buscopan, relieves spasms of smooth muscles throughout digestive system, including biliary and urinary tracts.

The described drug is much more effective than Duspatalin, has more wide list indications:

Which is better - Duspatalin or Odeston?

Although they have similar effects, the two medications have different purposes. Duspatalin relieves spasms caused by tension in the smooth muscles of the intestines, while Odeston relieves pain associated with insufficient bile production. The latter medication is better if attacks are provoked by hypokinetic or hyposecretion of bile. Duspatalin is preferable for intestinal disorders.

For all its effectiveness, confirmed more than once positive reviews, Duspatalin has a number of features due to which people do not always tolerate this drug equally well. There are times when the nearest pharmacy does not have it in stock, but the spasm needs to be relieved somehow, in similar situation Duspatalin analogues will help. The pharmaceutical industry offers several options at once. So, what is good about Duspatalin and its analogues and substitutes?

Duspatalin - composition and action

Main active ingredient The drug Duspatalin is mebeverine hydrochloride. It helps eliminate spasm by relaxing the smooth muscles of the intestines. Pain relief occurs immediately after muscle relaxation. The drug is packaged in capsules coated with a safe gelatin shell, which is easily digested and ensures rapid absorption of the active substance into the blood.

It should be taken before meals twice a day. The drug is eliminated naturally.

The only contraindication is hypersensitivity to the components, which can cause a mild side effect in the form of an allergic reaction.

The only serious disadvantage of Duspatalin is its rather high price, associated with the geographical remoteness of the manufacturing company, which is located in the Netherlands.

Analogues

There is a fairly extensive list of drugs that have an effect similar to Duspatalin. The difference between these drugs is a more affordable price and wider availability.

Bendazole

The drug Bendazole, named after the main active ingredient, provides relief from spasms blood vessels, caused by the most for various reasons. It also helps with flare-ups that occur in people with hypertension. Active components Bendazole helps relax spasmodic smooth muscles of internal organs, including gastrointestinal tract.

The release form is a powder that must be dissolved in water and taken 2 hours before or after a meal.

Bendazole is contraindicated in hypersensitivity to its components may cause side effects in the form of an allergic reaction.

Buscopan

A substance called hyoscine butyl bromide, contained in Buscopan, relieves spasms that occur in the smooth muscles of the entire digestive system and helps provide pain relief in the organs of the excretory system.

The list of indications for this drug is even wider than that of Duspatalin, and the effectiveness is much higher when various kinds colic, diseases of the gallbladder and liver, during exacerbation peptic ulcer. Buscopan is available in the form of suspension, tablets, rectal suppositories and solution for intravenous administration.

The drug is contraindicated in case of hypersensitivity to the components, intestinal and stomach obstruction. Side effects of Buscopan include dry mucous membranes, bloating, angina, sleep disturbances and allergic reactions.

Dibazol

The active substance dibazole in this composition medicine provides therapeutic effect on the smooth muscles of the blood vessels of internal organs, helps relieve muscle spasms, and has vasodilating properties. In some cases, Dibazol a short time can lower blood pressure.

Available in tablet form different dosages for children and adults, solution for intramuscular or intravenous administration, as well as suppositories for rectal use.

May cause allergies, and in some cases, fever and dizziness. Not recommended for those with hypersensitivity, as well as in old age.

Dicetel

Dicetel contains pinaverium bromide, which reduces the sensitivity of neurons, thereby reducing pain in the gastrointestinal tract. The drug helps eliminate discomfort resulting from malfunction intestines and relieve spasms.

Dicetel also helps with biliary tract disorders and gallbladder diseases. The drug is sold in tablet form and should be taken 3 times a day with meals.

Contraindicated during pregnancy, allergies and childhood. May cause dyspepsia, nausea, constipation.

Drotaverine hydrochloride

Drotaverine hydrochloride, contained in the drug of the same name, relieves spasms of the smooth muscles of internal organs; it is prescribed for renal and biliary colic, diseases of the stomach and duodenum, cholecystitis, constipation. The drug helps eliminate pain.

Available, as a rule, in capsules, tablets and in the form of an injection solution.

Contraindicated in case of hypersensitivity to the active substance, renal failure, vascular pathologies, on early stages pregnancy. May cause dizziness, rapid heartbeat, sweating, lowers blood pressure.

Mebeverine

Mebeverine, named after its main active ingredient, is usually prescribed to adult patients. It is used in the treatment of spasms in the gastrointestinal tract caused by various diseases.

The drug helps with colic and various intestinal disorders. IN in some cases The drug is allowed to be used by children over 12 years of age; in all other cases, consultation with a doctor is necessary. Available in tablet form. The drug should be taken strictly before meals.

Contraindicated for pregnant women and people with allergies. May cause headache, constipation, urticaria and swelling.

Niaspam

Contraindicated for children and pregnant women, as well as people with hypersensitivity to the components. Capable of provoking allergic reactions on the skin, in some cases it can have a stimulating effect on nervous system.

No-shpa

No-shpa contains active substance drotaverine and is used as a supplement in the treatment of spasms that occur in the smooth muscles of the intestines and stomach. Positive influence This drug helps with peptic ulcers, flatulence, colitis and constipation. Available in tablets and capsules, and in the form of a solution for intravenous administration.

Contraindicated in patients with hepatic and renal insufficiency, low blood pressure, as well as women during breastfeeding. Components of the drug may cause increased sweating, fever, rapid heartbeat.

Papaverine

The scope of action of the active substance papaverine is quite wide. It can be a good replacement for Duspatalin in the treatment of spasms of muscles and blood vessels of internal organs. The drug is used in the treatment of hypertensive crisis, in the treatment of renal colic, stomach diseases, and some diseases of the cerebral vessels.

In some cases, Papaverine is prescribed for angina pectoris and pathologies urinary tract. Available in the form of tablets and capsules, rectal suppositories and solution for injection.

Contraindicated in liver failure, glaucoma, dysfunction thyroid gland, as well as for some heart diseases. May cause allergic reactions, drowsiness, and heart rhythm disturbances.

Sparex

One of the most budget analogues Duspatalin, which helps relieve spasms that occur in the muscles of internal organs. It contains active substance mebeverine, which can be used by children and pregnant women, but only with the permission of the attending physician. Available in capsule form long acting, which must be taken twice a day before meals.

Contraindicated in case of hypersensitivity to the components. Side effects manifest themselves in the form of allergic reactions.

Spascuprel

Spascuprel is a homeopathic collection consisting of several active ingredients (citrullus, ammonium bromatum, atropinum sulfuricum, veratrum album, magnesium phosphoricum and others). According to the instructions, Spascuprel is prescribed to patients in the presence of spasms of the intestines, stomach and gall bladder, as well as for diseases urinary system and genitals.

The active ingredients of the drug provide relief muscle tension and return to normal tone. Available in the form of tablets, which need to be taken 1 piece 3 times a day.

Contraindicated in case of hypersensitivity to the components, as it can provoke allergic reactions.

Trigan-D

The drug contains the active substances paracetamol and dicycloverine, has positive impact in the treatment of pain of various origins. Promotes removal discomfort caused by disorders of the gastrointestinal tract.

Trigan-D is recommended for renal or hepatic colic and helps overcome the symptoms of irritable bowel syndrome and a number of other disorders. Available in the form of tablets that must be taken 2-3 times a day.

Contraindicated in case of hypersensitivity to the components, renal failure, during feeding and under the age of 3 years. The drug may cause allergic reactions, nausea, dizziness, dry mouth, vomiting reflex, anemia.

Trimedat

The therapeutic effect of the drug protects the smooth muscles of the gastrointestinal tract from food irritants. Available in tablet form. The drug should be taken 3 times a day.

Diseases of the gastrointestinal tract in modern world Not unusual. A fast pace of life, poor diet, stress and other reasons lead to functional and more serious illnesses Gastrointestinal tract. In the article we'll talk O modern drug whose name is “Duspatalin”. Its analogues will be considered, and also given comparative assessment some duspatalin substitutes.

Duspatalin - brief instructions

Mebeverine hydrochloride is the active substance of the drug. ICD-10 code – ATX A0ZA A04. Refers to anticholinergic drugs. Release form: tablets (135 g of active substance) and capsules (200 g of mebeverine). Produced in the Netherlands.

Mebeverine has a pronounced antispasmodic property. The effect of the drug is selective, it mainly affects the smooth muscles of the digestive system, while intestinal motility remains unchanged.

When is duspatalin indicated?

Direct indications for use are:

• irritable bowel syndrome (flatulence, colic, constipation, diarrhea);
• spasm of the gastrointestinal tract (GIT);
• pain in the epigastric region (abdominal pain);
• pathologies of the biliary tract.

Contraindications

Mebeverine is not used in following cases:

• individual intolerance;
• pregnancy and lactation;
• childhood up to 10 years.

How to take duspatalin?

Usually the treatment plan is prescribed by the doctor. The duration of the appointment is also agreed with the specialist. According to the instructions for use, for example, if we consider duspatalin in capsules, the drug is taken 1 capsule twice a day.

Possible adverse reactions

Duspatalin rarely causes side effects; such side effects are quite rare. negative symptoms as: constipation, diarrhea, nausea, headache or dizziness, allergic reactions.

The average cost of duspatalin in Russia is 500–600 rubles.

Duspatalin analogues are cheaper

It can't be said that this remedy has an exorbitant price, but still the search for cheaper substitutes does not stop. This means that this price is not suitable for everyone, especially in cases where the patient suffers chronic disorders The gastrointestinal tract and duspatalin have to be purchased repeatedly. Good inexpensive means exist, we will discuss them below.

Duspatalin is usually changed for two reasons: the price is not satisfactory, or the patient experiences adverse reactions. First of all, you need to know that only a specialist can replace the drug; there can be no amateur activity in this matter.

As cheap analogues Russian production The following drugs may be considered:

• mebeverine;
• sparex;
• papaverine.

• dicetel;
• trimedate;
• no-shpa;
• buscopan;
• Odeston;
• niaspam.

Let's take a closer look at the presented drugs.

Russian analogues of duspatalin

Mebeverine

Russian mebeverine is a structural analogue of duspatalin, since their active substance is completely the same. The drug is produced in capsules, the action of which has a prolonged effect. The drug is prescribed for heartburn, nausea, and spastic pain in the epigastrium. The drug is also used for pancreatitis, when the patient develops vomiting. The drug is not recommended for use under 18 years of age. As for possible side effects, they are the same as for duspatalin.

The average price of capsules is about 350 rubles.

Sparex

Like mebeverine, sparex is a structural analogue of duspatalin. Indications, contraindications, and side effects are not particularly different. Sparex has a capsule release form. The drug is not recommended for use under 12 years of age. IN in rare cases, short-term, the drug is prescribed before this age, for example, with severe pain in the epigastrium. Sparex can be used for gastric ulcers, pancreatitis, colic localized in the liver and kidneys.

The price for a package of sparex is about 350 rubles.

Papaverine

The active ingredient is papaverine hydrochloride. The product has been successfully used to relieve liver and renal colic. Recommended for pylorospasm, cholelithiasis, cerebral vascular spasm. The product is available in tablets, suppositories, and solution for injection.

Tablets in a dosage of 40 mg No. 20 cost about 60 rubles.

Foreign analogues

Niaspam

The drug has a myotropic effect. Country of origin: India. The active ingredient is mebeverine hydrochloride. It is a structural analogue of duspatalin. The main task of niaspam is to eliminate functional disorders large intestine. The drug has a pronounced antispasmodic effect. The drug is not recommended for children under 12 years of age.

Capsules 20 mg No. 30 cost about 380 rubles.

Trimedat

The drug is classified as an antispasmodic that relieves pain and discomfort in the gastrointestinal tract. The name of the active substance matches the name of the drug. Trimedat is available in tablets. Manufacturer: Korea.

The price for trimedat is around 450 rubles.

Odeston

The active ingredient is hymecromone. Country of origin: Poland. The drug is available in tablet form. Odeston has a pronounced antispasmodic effect, and also has choleretic effect. Compared with duspatalin, the drug has more wide application. It is also prescribed in the following cases: all problems associated with dysfunction of the gallbladder (dyskenesia, cholecystitis and others).

The disadvantage of odeston is that it has contraindications for use: hemophilia, severe kidney and liver pathologies, childhood, gastrointestinal ulcers, others. Adverse reactions more often associated with migraines and allergic manifestations.

The price for a package of Odeston is 360 rubles.

Buscopan

The drug is produced in France and Austria. Refers to cholinomimetics, perfectly prevents spasms of the intestines (small and large), stomach and gall bladder. It has two forms of release: tablets and suppositories. The product is based on the active substance butyl bromide hyoscine.

Buscopan is effective for various spasms; it is prescribed for attacks of colic, intestinal dysfunction, pylorospasm, cardiospasm and other problems.

Contraindications for use: myasthenia gravis, pulmonary edema, atherosclerosis, others. Possible adverse reactions: severe drowsiness, dry mouth, tachycardia.

The average price for a buscopan is around 370 rubles.

No-shpa

The product is produced in France. It is a cheap substitute for duspatalin.

Many doctors believe that no-spa is one of the cheapest substitutes for duspatalin. Has a pronounced myotropic effect. It exhibits a strong analgesic effect, so it is often used to relieve renal and hepatic colic, as well as attacks of other etiologies. Release form: tablets and solution for injection. The active substance is drotaverine (antispasmodic).

• Indications: spasms various organs. Approved for use in obstetric practice.
• Contraindications: severe functional disorders liver, kidneys, heart, children under 6 years of age, lactation period, individual intolerance to the composition. Side effects occur extremely rarely: migraine, insomnia, tachycardia, hypotension, dyspepsia.

A package of 40 mg tablets No. 100 can be purchased for 250 rubles.

Dicetel

Pinaveria bromide is the main active ingredient. Refers to m-anticholinergics. Produced in France. Release form: tablets.

It is used to relieve spasms and colic in diseases of the gastrointestinal tract. Dicetel is also used as a preparation for endoscopic procedures. The drug is well tolerated, sometimes adverse reactions occur: diarrhea, nausea, allergies.

Currently, dicetel costs slightly less than duspatalin, and in some pharmacies it is even more expensive.

When choosing antispasmodics, patients sometimes do not know what is best to buy. Specialists often offer several drugs to choose from, and it turns out that the right to choose remains with the patient. Let's compare a few pairs antispasmodics and try to determine which one is more effective and cheaper.

Comparative assessment of duspatalin and its analogues

Trimedat or duspatalin - which is better?

The main indication for the use of these drugs is irritable bowel syndrome. Pharmacological group, to which these drugs belong - myotropic antispasmodics.

Fundamental differences:

• main cast;
• auxiliary staff;
• company manufacturer;
• price;
• operating principle;
• release form;

Mebeverine is the active substance of duspatalin, trimebutine is the main component of trimedate. Both drugs have tablet form; only duspatalin has capsules.

With pronounced pain syndrome It is better to use duspatalin; for constipation, trimedate is recommended. Duspatalin has an advantage as an antispasmodic.

Trimedat is not used in children under three years of age, duspatalin is allowed only after 10 years of age. During the lactation period, the drugs in question are not used. During pregnancy, only in exceptional cases, in II and III trimesters trimedate may be used.

The price of trimedate is lower, approximately 15%.

Sparex or duspatalin - what to choose

The drugs are structural analogs; the composition differs only in the auxiliary components. The Russian manufacturer produces only capsules, and duspatalin (Netherlands) also has tablets, where the dosage of the drug is lower. This allows therapy to be adjusted when the daily dosage needs to be reduced.

Since the products have identical composition, the indications and contraindications are basically the same. Sometimes side reactions are observed, for example, when taking duspatalin there are none, but there is a reaction to Sparex; rather, such “side effects” are associated with some kind of auxiliary substance.

Whatever one may say, price remains one of the priorities when choosing a medicine. No matter how much they praise, for example, foreign drug, it is difficult to convince a person that only it needs to be purchased. This is especially problematic if the patient’s purchasing power is low. Therefore, specialists should always take this point into account and select funds according to the financial capabilities of the patient.

It should be noted that drugs are not always imported production better. Practitioners have experience in using various drugs, therefore, a competent doctor will always tell the patient which remedy to choose.

Comparing the price of duspatalin and sparax, we can conclude that the first product is 30–40% more expensive.

Duspatalin or Niaspam

These funds structural analogues, therefore, according to pharmacological action identical. The capsule dosages of these products are also the same. The effect of the drugs is prolonged.

The drugs differ only in cost, manufacturer and composition excipients. Niaspam can be used from 12 years of age, duspatalin is allowed from 10 years of age.

Duspatalin is 30% more expensive than Niaspam.

Herbal analogues that relieve intestinal spasms

There is a certain category of patients who do not want to take any chemicals, considering such therapy to be deadly for the body. Of course, you can’t think so unambiguously, sometimes without certain drugs not enough. For example, it is impossible to cure tuberculosis without antibiotics.

Herbal remedies are usually included in complex therapy and contribute to more rapid recovery body. Let's look at a few simple recipes, relieving spasms, where cheap analogues of duspatalin are medicinal plants.

Medicinal mixture for intestinal spasms (infusion)

Compound:

• sage;
• plantain;
• peppermint;
• St. John's wort;
• cottonweed.

You will need 10 grams of dried herbs, 5 grams of mint, and 15 grams of other herbs. All herbs need to be mixed, the collection is ready. In order for the collection to be beneficial, it is very important to properly harvest medicinal plants. If you have no experience in this matter, it is better to purchase finished products at a pharmacy.

Now let's move on to preparing the infusion. You need to pour 5 grams of the collection with boiling water (200–300 ml). Leave for 20 minutes, strain. Divide the resulting infusion into three parts and drink throughout the day.

Peppermint infusion

Many have heard that mint not only calms the nervous system, but is also an excellent antispasmodic. Mint infusion is taken for headaches, intestinal spasms, menstrual pain. Mint is brewed both dry and fresh. Usually they take a glass of boiling water dessert spoon dry raw materials. After 15 minutes the infusion is ready. It is recommended to drink this infusion twice a day.

If you are outside the city, please note that a lot of wild mint grows near ponds and lakes, in its own way. medicinal properties it exceeds peppermint. Therefore, do not be lazy, pick mint and dry it. Such a preparation will help out more than once when nervous excitement and stomach pain.

Horsetail, yarrow and wormwood

The mixture of these plants has a beneficial effect on the smooth muscles of the gastrointestinal tract. Horsetail and yarrow take 20 grams each, then add 10 grams of wormwood. Everything is mixed. The resulting mixture is poured with 0.5 liters of boiling water. Leave for about two hours, then filter. Take 50 ml 4 times a day.

The course of treatment is at least five days, even if the pain in the intestines has gone away on the second day. It is necessary to “calm” the gastrointestinal tract as much as possible, especially in cases where the patient has irritable bowel syndrome.

Dill (infusion)

Dill - excellent remedy to prevent and relieve intestinal spasms. In summer it is better to infuse fresh dill seeds, in winter - dry ones. Pour 200 ml of boiling water over a tablespoon of seeds and let stand for 15 minutes. You can also take dill greens in the summer. It is brewed in the same way.

People with gastrointestinal problems need to constantly include dill in their diet. If there is a baby living in the house, stock up dill water(buy at the pharmacy), it relieves colic perfectly.

Flaxseed (infusion)

This plant belongs to the plantain family. The infusion is prepared as follows: pour a tablespoon of herbs into 300 ml of boiling water. Leave for about 20 minutes, strain. Take a tablespoon every four hours. The course of therapy for gastrointestinal diseases lasts two weeks. A month later, the treatment is repeated.

Conclusion

Duspatalin is a worthy and noteworthy drug that eliminates pain and spasms during various violations in the functioning of the gastrointestinal tract. Despite this, many patients are interested in analogues.

The article provided a list of cheap analogues, given Comparative characteristics duspatalin and some of its analogues. We hope that the information presented will help patients understand not so simple issues of medicine and pharmacology. Be healthy!

Prohibited during pregnancy