Coagulopathy code according to ICD 10. Hypercoagulation syndrome. D71 Functional disorders of polymorphonuclear neutrophils

• D65 Disseminated intravascular coagulation [defibration syndrome]. Afibrinogenemia acquired. Consumptive coagulopathy. Diffuse or disseminated intravascular coagulation (DJC). Acquired fibrinolytic bleeding. Purpura: fibrinolytic, fulminant.
  • Deleted: defibration syndrome (complicating): abortion, ectopic or molar pregnancy (O00 - O07, O08.1), in the newborn (P60), pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72. 3)
• D66 Hereditary factor VIII deficiency. Factor VIII deficiency (with functional impairment) Hemophilia: NOS, A, classic.
  • Deleted: factor VIII deficiency with vascular disorder (D68.0)
• D67 Hereditary deficiency of factor IX. Christmas disease. Deficiency: factor IX (with functional impairment), thromboplastic plasma component, Hemophilia B
• D68 Other coagulation disorders.
  • Excluded complicating: abortion, ectopic or molar pregnancy (O00-O07, O08.1), pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)
  • D68.0 Von Willebrand's disease. Angiohemophilia. Factor VIII deficiency with vascular impairment. Vascular hemophilia.
  • Excluded: hereditary capillary fragility (D69.8), factor VIII deficiency: NOS (D66), with functional impairment (D66)
  • D68.1 Hereditary factor XI deficiency. Hemophilia C. Deficiency of plasma thromboplastin precursor.
  • D68.2 Hereditary deficiency of other coagulation factors. Congenital afibrinogenemia. Deficiency: AC globulin, proaccelerin. Factor deficiency: I (fibrinogen), II (prothrombin), V (labile), VII (stable), X (Stewart-Prower), XII (Hageman), XIII (fibrin-stabilizing). Dysfibrinogenemia (congenital). Hypoproconvertinemia Ovren's disease
  • D68.3 Hemorrhagic disorders caused by anticoagulants circulating in the blood. Hyperheparinemia Increased levels of: antithrombin, anti-VIIIa, anti-IXa, anti-Xa, anti-XIa.
  • D68.4 Acquired coagulation factor deficiency. Coagulation factor deficiency due to: liver disease, vitamin K deficiency.
  • Excluded: vitamin K deficiency in the newborn (P53)
  • D68.8 Other specified bleeding disorders. Presence of systemic lupus erythematosus inhibitor
  • D68.9 Coagulation disorder, unspecified
• D69 Purpura and other hemorrhagic conditions.
  • Excluded: benign hypergammaglobulinemic purpura (D89.0), cryoglobulinemic purpura (D89.1), idiopathic (hemorrhagic) thrombocythemia (D47.3), purpura fulminans (D65), thrombotic thrombocytopenic purpura (M31.1)
  • D69.0 Allergic purpura. Purpura: anaphylactoid, Henoch (- Schonlein), non-thrombocytopenic: hemorrhagic, idiopathic, vascular. Allergic vasculitis.
  • D69.1 Qualitative platelet defects. Bernard-Soulier syndrome (giant platelets), Glanzmann's disease, Gray platelet syndrome, Thrombasthenia (hemorrhagic) (hereditary). Thrombocytopathy.
  • Excluded: von Willebrand disease (D68.0)
  • D69.2 Other non-thrombocytopenic purpura. Purpura: NOS, senile, simple.
  • D69.3 Idiopathic thrombocytopenic purpura. Evans syndrome
  • D69.4 Other primary thrombocytopenias.
  • Excluded: thrombocytopenia with absent radius (Q87.2), transient neonatal thrombocytopenia (P61.0), Wiskott-Aldrich syndrome (D82.0)
  • D69.5 Secondary thrombocytopenia
  • D69.6 Thrombocytopenia, unspecified
  • D69.8 Other specified hemorrhagic conditions. Capillary fragility (hereditary). Vascular pseudohemophilia.
  • D69.9 Hemorrhagic condition, unspecified

- (from Lat. coagulum coagulation and...pathy) painful conditions caused by blood clotting disorders... Big Encyclopedic Dictionary

- (from Lat. coagulum coagulation and...pathy), painful conditions caused by impaired blood clotting. * * * COAGULOPATHY COAGULOPATHY (from Latin coagulum coagulation and Greek pathos suffering, disease), painful conditions,… … encyclopedic Dictionary

- (coagulopathia; coagulo + Greek pathos suffering, disease) dysfunction of the blood coagulation system ... Large medical dictionary

- (from Lat. coagulum coagulation and...pathy), painful conditions caused by impaired blood clotting... Natural science. encyclopedic Dictionary

coagulopathy- coagulopathy, and... Russian spelling dictionary

- (p. haemorrhagica; synonym inhibitory form of bleeding) K., the main manifestation of which is hemorrhagic diathesis ... Large medical dictionary

K., caused by a sharp decrease in the blood level of factors I, II, V, VII, VIII, XIII and the number of platelets that occurs after massive blood loss, in shock, burn disease, intravascular hemolysis and some other conditions... Large medical dictionary

I Poisoning (acute) Poisoning is a disease that develops as a result of exogenous exposure to the human or animal body of chemical compounds in quantities that cause disturbances in physiological functions and create a danger to life. IN … Medical encyclopedia

Coagulopathy is a process in which abnormalities occur in the blood clotting system. It is characterized by extensive nasal hemorrhages, lack of iron in the blood, as well as the formation of large hematomas on the skin.

Pathology can be transmitted from mother to child and develop throughout a person’s life. In the latter case, there is a sufficient amount of formed components in the blood, but their quality suffers.

In a normal state, a sufficient amount of hemoglobin protein, platelets and red blood cells circulate in the body in dynamic equilibrium. When there is open bleeding, the body initiates a process called coagulation., so that the blood coagulates and is delivered to the site of injury, stopping the bleeding.

Clogging of the wound occurs with the help of adhesive platelets, which replace the damaged walls of blood vessels and arteries.

ICD-10

According to the classification of coagulopathy according to the International Classification of Diseases, coagulopathy belongs to the class “Bleeding disorders, purpura and others,” with coding D65.

Types of coagulopathy

The occurrence of blood clotting abnormalities has many different causes, but is divided into types solely according to the method of occurrence. There are two main types of coagulopathy:

Progressive throughout life. Pathology is acquired during the development of diseases, and is a complication against the background of another disease, being one of the symptoms.

Coagulopathy is mainly observed in infections caused by bacteria and malignant tumors. Some medications can also cause bleeding disorders.

Transmitted from mother to child. In this case, the pathology is congenital, and the disorder occurs at the level of homeostasis. The qualitative composition of formed elements is affected by a decrease in the saturation of biologically active substances in the blood.

There is a failure in the platelet formation system. Hereditary coagulopathies are divided into forms, depending on the absence of one or another component during the formation of a blood clot.

With extensive blood loss, the body cannot quickly restore the normal quantitative concentration of formed elements, which leads to a decrease in blood clotting and leads to coagulopathy.

Blood loss and cardiac arrest lead to death in patients, without taking effective therapy.

The general name for all forms of congenital coagulopathy is hemophilia.

And they are characterized by insufficient thromboplastin saturation.

The congenital form is divided into three more types, based on blood clotting factors:

• Group A. This subtype is characterized by insufficient saturation with antihemophilic globulin;
• Group B. Characterized by abnormalities in the balance of the Christmas factor (blood coagulation factor IX, alpha globulin protein);
• Group C. Progresses due to insufficient amount of factor IX, which precedes thrombolastin.

Symptoms during the development of various forms of congenital pathology do not differ significantly. The first two forms affect only the male sex, a consequence of transmission of the disease from a woman, this is influenced by the X chromosome.

The last form (group C) can affect both men and women; this coagulopathy is not associated with chromosomal inheritance.

Developing throughout life include a large number of different conditions that manifest themselves in the form of coagulation disorders and bleeding. Gender does not play a role; it is mainly related to genetics.

In some cases, coagulopathy may be a consequence of the production of low amounts of prothrombin.

Its formation occurs in the intestines, with the help of vitamin K, bile and gastric juice.

With intestinal pathologies, infectious lesions, lack of vitamins in the liver, all this leads to a reduced formation of prothrombin, or the process of its absorption by the body is disrupted.

In many cases, coagulopathy associated with a high concentration of fibrin in the blood is recorded, which leads to a decline in fibrinogen. All this leads to thrombocytopenia (decreased platelet count), which in turn provokes increased bleeding.

What causes low blood clotting?

All types of low coagulability progress rapidly in the body.

The following factors can provoke coagulopathy:

An aggravation of less blood clotting occurs when bacteria and viruses are present in the body.

One of the sharp exacerbations occurs with kidney failure. Since at this moment the blood is filtered less, and there is a greater accumulation of toxins and wastes that stagnate in the blood.

During periods of bearing a child, when the increasing size of the uterus puts pressure on the urethra and there is a load on the kidneys, reduced blood filtration in the kidneys and stagnation of waste are often recorded. Bed rest helps restore healthy blood circulation.

How to identify symptoms?

Symptoms are the same for both types of coagulopathy. An accurate diagnosis is made by a qualified doctor.

If you notice the following symptoms, you should go to the hospital for examination:

Prolonged blood loss leads to the loss of large amounts of vitamin B and iron.

In childhood, coagulopathy is very dangerous, since at the stage of formation of the body a large amount of vitamins and iron is needed.

What happens during pregnancy?

Predominantly coagulopathy develops in pregnant women with the occurrence of some pathologies presented below:

• Disease of the circulatory system and formation of blood cells;
• Diseases caused by a lack of vitamins in the body;
• Varicose veins;
• Thrombophlebitis of a chronic nature (is an inflammation of the venous walls, with the formation of blood clots in them).

Women who have had significant blood losses in the past and are burdened with thromboembolism are at greater risk. People suffering from diabetes are also prone to developing coagulopathy.

Such women should be monitored by a doctor throughout the entire period of pregnancy., regularly undergoing tests and examinations, as well as taking prescribed courses of therapy. In most cases, such expectant mothers are admitted to a hospital for the entire duration of pregnancy.

Establishing diagnosis

Initially, you need to come for an examination to a doctor. At the first meeting, he listens to the patient’s complaints and performs an initial examination, studying the anamnesis. After which, if coagulopathy is suspected, the doctor will order blood tests (clinical and biochemical), as well as a urine test.

If the results of a urine test contain a large amount of calcium, suspicions arise about the presence of malignant tumor formations in the body, which lead to bleeding.

If a large amount of proteins is found in the urine, then perform an ultrasound of the kidneys to determine their performance and activity.

Among blood tests, the main stages that doctors pay attention to are:

Due to the fact that coagulopathy can be only one of the symptoms of the disease, examinations of the body are carried out to identify pathologies of organs, blood and vessels.

Among them:

The choice of the study is at the discretion of the doctor, taking into account additional symptoms and complaints of the patient.

How is low coagulation treated?

For an effective course of treatment, it is necessary not only to constantly take medications, but also to lead a healthy lifestyle and diet. The main goal of therapy is to eliminate the cause that caused the disease.

In case of severe injury, a patient with coagulopathy requires urgent hospitalization. In reanimation replenish lost blood using special solutions in the form of droppers. In case of large blood losses, a transfusion of compatible donor blood is given.

To normalize coagulation to the desired level, certain medications are mainly used:

• Iron-containing preparations (Fenuls, Sorbifer);
• Antibiotics (Clarithromycin, Amoxiclav, Amoxicillin);
• Chemotherapeutic agents;
• Plasma substitutes;
• Consumption of complexes of vitamins and minerals;
• Antispasmodics (Drotaverine, Spazgan);
• Glucocorticosteroids (Dexamethasone, Prednisolone).

To stop open bleeding in a patient with coagulopathy, a homeostatic collagen sponge or powder is used. When if they do not bring any effect, then the spleen is removed, by surgery.

Preventive actions

There are no special measures to prevent coagulopathy.

• Regular examinations;
• Avoiding traumatic situations. It is necessary to prevent possible injuries, since bleeding stops slowly. And large injuries, with coagulopathy, can lead to disastrous consequences;
• Proper nutrition. Another key to preventing many diseases is a balanced, proper diet. You should consume more foods rich in vitamin K (spinach, soy, strawberries, potatoes, veal, tomatoes, cod, cauliflower, rose hips).

What's the forecast?

With timely access to the hospital, proper examination and taking an effective course of complex therapy, the outcome is favorable. The level of coagulation is successfully maintained with medications.

If coagulopathy is a symptom of another disease, then the course of treatment is aimed at eliminating the root cause. A healthy lifestyle, proper diet and giving up bad habits, will help not only normalize coagulation, but also prevent coagulopathy.

If you do not pay attention to the symptoms and ignore visiting a doctor, this can lead to disastrous consequences. With medium-sized wounds, heavy bleeding occurs, which are very difficult to stop, which can lead to large blood losses and cardiac arrest.

If you notice any symptoms, consult a doctor! Do not self-medicate and be healthy!

Class III. Diseases of the blood, hematopoietic organs and certain disorders involving the immune mechanism (D50-D89)

Excluded: autoimmune disease (systemic) NOS (M35.9), certain conditions arising in the perinatal period (P00-P96), complications of pregnancy, childbirth and the puerperium (O00-O99), congenital anomalies, deformities and chromosomal disorders (Q00- Q99), endocrine diseases, nutritional and metabolic disorders (E00-E90), disease caused by human immunodeficiency virus [HIV] (B20-B24), trauma, poisoning and certain other consequences of external causes (S00-T98), neoplasms (C00-D48), symptoms, signs and abnormalities identified by clinical and laboratory tests, not classified elsewhere (R00-R99)

This class contains the following blocks:
D50-D53 Anemia associated with nutrition
D55-D59 Hemolytic anemias
D60-D64 Aplastic and other anemias
D65-D69 Bleeding disorders, purpura and other hemorrhagic conditions
D70-D77 Other diseases of the blood and hematopoietic organs
D80-D89 Selected disorders involving the immune mechanism

The following categories are marked with an asterisk:
D77 Other disorders of the blood and hematopoietic organs in diseases classified elsewhere

NUTRITION-RELATED ANEMIA (D50-D53)

D50 Iron deficiency anemia

Included: anemia:
. sideropenic
. hypochromic
D50.0 Iron deficiency anemia secondary to blood loss (chronic). Posthemorrhagic (chronic) anemia.
Excludes: acute posthemorrhagic anemia (D62) congenital anemia due to fetal blood loss (P61.3)
D50.1 Sideropenic dysphagia. Kelly-Paterson syndrome. Plummer-Vinson syndrome
D50.8 Other iron deficiency anemias
D50.9 Iron deficiency anemia, unspecified

D51 Vitamin B12 deficiency anemia

Excludes: vitamin B12 deficiency (E53.8)

D51.0 Vitamin B12 deficiency anemia due to intrinsic factor deficiency.
Anemia:
. Addison
. Birmera
. pernicious (congenital)
Congenital intrinsic factor deficiency
D51.1 Vitamin B12 deficiency anemia due to selective malabsorption of vitamin B12 with proteinuria.
Imerslund(-Gresbeck) syndrome. Megaloblastic hereditary anemia
D51.2 Transcobalamin II deficiency
D51.3 Other vitamin B12 deficiency anemias associated with diet. Anemia of vegetarians
D51.8 Other vitamin B12 deficiency anemias
D51.9 Vitamin B12 deficiency anemia, unspecified

D52 Folate deficiency anemia

D52.0 Diet-related folate deficiency anemia. Megaloblastic nutritional anemia
D52.1 Folate deficiency anemia is drug-induced. If necessary, identify the drug
use an additional external cause code (class XX)
D52.8 Other folate deficiency anemias
D52.9 Folate deficiency anemia, unspecified. Anemia due to insufficient intake of folic acid, NOS

D53 Other diet-related anemias

Includes: megaloblastic anemia not responding to vitamin therapy
nom B12 or folate

D53.0 Anemia due to protein deficiency. Anemia due to amino acid deficiency.
Orotaciduric anemia
Excludes: Lesch-Nychen syndrome (E79.1)
D53.1 Other megaloblastic anemias, not elsewhere classified. Megaloblastic anemia NOS.
Excludes: DiGuglielmo disease (C94.0)
D53.2 Anemia due to scurvy.
Excludes: scurvy (E54)
D53.8 Other specified diet-related anemias.
Anemia associated with deficiency:
. copper
. molybdenum
. zinc
Excludes: malnutrition without mention of
anemia, such as:
. copper deficiency (E61.0)
. molybdenum deficiency (E61.5)
. zinc deficiency (E60)
D53.9 Diet-related anemia, unspecified. Simple chronic anemia.
Excludes: anemia NOS (D64.9)

HEMOLYTIC ANEMIA (D55-D59)

D55 Anemia due to enzyme disorders

Excludes: drug-induced enzyme deficiency anemia (D59.2)

D55.0 Anemia due to glucose-6-phosphate dehydrogenase [G-6-PD] deficiency. Favism. G-6-PD deficiency anemia
D55.1 Anemia due to other disorders of glutathione metabolism.
Anemia due to deficiency of enzymes (except G-6-PD) associated with hexose monophosphate [HMP]
bypass of the metabolic pathway. Hemolytic nonspherocytic anemia (hereditary) type 1
D55.2 Anemia due to disorders of glycolytic enzymes.
Anemia:
. hemolytic non-spherocytic (hereditary) type II
. due to hexokinase deficiency
. due to pyruvate kinase deficiency
. due to triosephosphate isomerase deficiency
D55.3 Anemia due to disorders of nucleotide metabolism
D55.8 Other anemias due to enzyme disorders
D55.9 Anemia due to enzyme disorder, unspecified

D56 Thalassemia

D56.0 Alpha thalassemia.
Excludes: hydrops fetalis due to hemolytic disease (P56.-)
D56.1 Beta thalassemia. Cooley's anemia. Severe beta thalassemia. Sickle cell beta thalassemia.
Thalassemia:
. intermediate
. big
D56.2 Delta beta thalassemia
D56.3 Carriage of thalassemia trait
D56.4 Hereditary persistence of fetal hemoglobin [HFH]
D56.8 Other thalassemias
D56.9 Thalassemia unspecified. Mediterranean anemia (with other hemoglobinopathy)
Thalassemia minor (mixed) (with other hemoglobinopathy)

D57 Sickle cell disorders

Excludes: other hemoglobinopathies (D58. -)
sickle cell beta thalassemia (D56.1)

D57.0 Sickle cell anemia with crisis. Hb-SS disease with crisis
D57.1 Sickle cell anemia without crisis.
Sickle cell:
. anemia)
. disease) NOS
. violation )
D57.2 Double heterozygous sickle cell disorders
Disease:
. Hb-SC
. Hb-SD
. Hb-SE
D57.3 Carriage of the sickle cell trait. Carriage of hemoglobin S. Heterozygous hemoglobin S
D57.8 Other sickle cell disorders

D58 Other hereditary hemolytic anemias

D58.0 Hereditary spherocytosis. Acholuric (familial) jaundice.
Congenital (spherocytic) hemolytic jaundice. Minkowski-Choffard syndrome
D58.1 Hereditary elliptocytosis. Ellitocytosis (congenital). Ovalocytosis (congenital) (hereditary)
D58.2 Other hemoglobinopathies. Abnormal hemoglobin NOS. Congenital anemia with Heinz bodies.
Disease:
. Hb-C
. Hb-D
. Hb-E
Hemolytic disease caused by unstable hemoglobin. Hemoglobinopathy NOS.
Excludes: familial polycythemia (D75.0)
Hb-M disease (D74.0)
hereditary persistence of fetal hemoglobin (D56.4)
altitude-related polycythemia (D75.1)
methemoglobinemia (D74. -)
D58.8 Other specified hereditary hemolytic anemias. Stomatocytosis
D58.9 Hereditary hemolytic anemia, unspecified

D59 Acquired hemolytic anemia

D59.0 Drug-induced autoimmune hemolytic anemia.
If it is necessary to identify the drug, use an additional code for external causes (class XX).
D59.1 Other autoimmune hemolytic anemias. Autoimmune hemolytic disease (cold type) (warm type). Chronic disease caused by cold hemagglutinins.
"Cold agglutinin":
. disease
. hemoglobinuria
Hemolytic anemia:
. cold type (secondary) (symptomatic)
. thermal type (secondary) (symptomatic)
Excludes: Evans syndrome (D69.3)
hemolytic disease of the fetus and newborn (P55. -)
paroxysmal cold hemoglobinuria (D59.6)
D59.2 Drug-induced non-autoimmune hemolytic anemia. Drug-induced enzyme deficiency anemia.
If it is necessary to identify the drug, use an additional code for external causes (class XX).
D59.3 Hemolytic-uremic syndrome
D59.4 Other non-autoimmune hemolytic anemias.
Hemolytic anemia:
. mechanical
. microangiopathic
. toxic
If it is necessary to identify the cause, use an additional external cause code (class XX).
D59.5 Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli].
D59.6 Hemoglobinuria due to hemolysis caused by other external causes.
Hemoglobinuria:
. from load
. marching
. paroxysmal cold
Excludes: hemoglobinuria NOS (R82.3)
D59.8 Other acquired hemolytic anemias
D59.9 Acquired hemolytic anemia, unspecified. Chronic idiopathic hemolytic anemia

APLASTIC AND OTHER ANEMIA (D60-D64)

D60 Acquired pure red cell aplasia (erythroblastopenia)

Includes: red cell aplasia (acquired) (adults) (with thymoma)

D60.0 Chronic acquired pure red cell aplasia
D60.1 Transient acquired pure red cell aplasia
D60.8 Other acquired pure red cell aplasias
D60.9 Acquired pure red cell aplasia, unspecified

D61 Other aplastic anemias

Excluded: agranulocytosis (D70)

D61.0 Constitutional aplastic anemia.
Aplasia (pure) red cell:
. congenital
. children's
. primary
Blackfan-Diamond syndrome. Familial hypoplastic anemia. Fanconi anemia. Pancytopenia with developmental defects
D61.1 Drug-induced aplastic anemia. If necessary, identify the drug
use an additional code for external causes (class XX).
D61.2 Aplastic anemia caused by other external agents.
If it is necessary to identify the cause, use an additional code of external causes (class XX).
D61.3 Idiopathic aplastic anemia
D61.8 Other specified aplastic anemias
D61.9 Aplastic anemia, unspecified. Hypoplastic anemia NOS. Bone marrow hypoplasia. Panmyelophthisis

D62 Acute posthemorrhagic anemia

Excludes: congenital anemia due to fetal blood loss (P61.3)

D63 Anemia in chronic diseases classified elsewhere

D63.0 Anemia due to neoplasms (C00-D48+)
D63.8 Anemia in other chronic diseases classified elsewhere

D64 Other anemias

Excluded: refractory anemia:
. NOS (D46.4)
. with excess blasts (D46.2)
. with transformation (D46.3)
. with sideroblasts (D46.1)
. without sideroblasts (D46.0)

D64.0 Hereditary sideroblastic anemia. Sex-linked hypochromic sideroblastic anemia
D64.1 Secondary sideroblastic anemia due to other diseases.
If necessary, an additional code is used to identify the disease.
D64.2 Secondary sideroblastic anemia caused by drugs or toxins.
If it is necessary to identify the cause, use an additional code of external causes (class XX).
D64.3 Other sideroblastic anemias.
Sideroblastic anemia:
. NOS
. pyridoxine-reactive, not elsewhere classified
D64.4 Congenital dyserythropoietic anemia. Dyshematopoietic anemia (congenital).
Excludes: Blackfan-Diamond syndrome (D61.0)
DiGuglielmo disease (C94.0)
D64.8 Other specified anemias. Childhood pseudoleukemia. Leukoerythroblastic anemia
D64.9 Anemia, unspecified

BLOOD CLOTTING DISORDERS, PURPURA AND OTHERS

HEMORRHAGIC CONDITIONS (D65-D69)

D65 Disseminated intravascular coagulation [defibration syndrome]

Afibrinogenemia acquired. Consumptive coagulopathy
Diffuse or disseminated intravascular coagulation
Acquired fibrinolytic bleeding
Purpura:
. fibrinolytic
. lightning fast
Excluded: defibration syndrome (complicating):
. in a newborn (P60)

D66 Hereditary factor VIII deficiency

Factor VIII deficiency (with functional impairment)
Hemophilia:
. NOS
. A
. classical
Excludes: factor VIII deficiency with vascular disorder (D68.0)

D67 Hereditary factor IX deficiency

Christmas disease
Shortage:
. factor IX (with functional impairment)
. thromboplastic plasma component
Hemophilia B

D68 Other bleeding disorders

Excluded: complicating:
. abortion, ectopic or molar pregnancy (O00-O07, O08.1)
. pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)

D68.0 Von Willebrand's disease. Angiohemophilia. Factor VIII deficiency with vascular impairment. Vascular hemophilia.
Excludes: hereditary capillary fragility (D69.8)
factor VIII deficiency:
. NOS (D66)
. with functional impairment (D66)
D68.1 Hereditary factor XI deficiency. Hemophilia C. Plasma thromboplastin precursor deficiency
D68.2 Hereditary deficiency of other coagulation factors. Congenital afibrinogenemia.
Shortage:
. AC globulin
. proaccelerin
Factor deficiency:
. I [fibrinogen]
. II [prothrombin]
. V [labile]
. VII [stable]
. X [Stuart-Prower]
. XII [Hageman]
. XIII [fibrin stabilizing agent]
Dysfibrinogenemia (congenital). Hypoproconvertinemia. Ovren's disease
D68.3 Hemorrhagic disorders caused by anticoagulants circulating in the blood. Hyperheparinemia.
Content enhancement:
. antithrombin
. anti-VIIIa
. anti-IXa
. anti-Xa
. anti-XIa
If necessary, identify the anticoagulant used, use an additional external cause code.
(Class XX).
D68.4 Acquired coagulation factor deficiency.
Coagulation factor deficiency due to:
. liver diseases
. vitamin K deficiency
Excludes: vitamin K deficiency in the newborn (P53)
D68.8 Other specified bleeding disorders. Presence of systemic lupus erythematosus inhibitor
D68.9 Bleeding disorder, unspecified

D69 Purpura and other hemorrhagic conditions

Excludes: benign hypergammaglobulinemic purpura (D89.0)
cryoglobulinemic purpura (D89.1)
idiopathic (hemorrhagic) thrombocythemia (D47.3)
lightning purple (D65)
thrombotic thrombocytopenic purpura (M31.1)

D69.0 Allergic purpura.
Purpura:
. anaphylactoid
. Henoch(-Schönlein)
. non-thrombocytopenic:
. hemorrhagic
. idiopathic
. vascular
Allergic vasculitis
D69.1 Qualitative platelet defects. Bernard-Soulier syndrome [giant platelets].
Glanzmann's disease. Gray platelet syndrome. Thrombasthenia (hemorrhagic) (hereditary). Thrombocytopathy.
Excludes: von Willebrand disease (D68.0)
D69.2 Other non-thrombocytopenic purpura.
Purpura:
. NOS
. senile
. simple
D69.3 Idiopathic thrombocytopenic purpura. Evans syndrome
D69.4 Other primary thrombocytopenias.
Excludes: thrombocytopenia with absent radius (Q87.2)
transient neonatal thrombocytopenia (P61.0)
Wiskott-Aldrich syndrome (D82.0)
D69.5 Secondary thrombocytopenia. If it is necessary to identify the cause, use an additional external cause code (class XX).
D69.6 Thrombocytopenia, unspecified
D69.8 Other specified hemorrhagic conditions. Capillary fragility (hereditary). Vascular pseudohemophilia
D69.9 Hemorrhagic condition, unspecified

OTHER DISEASES OF THE BLOOD AND BLOOD FORMING ORGANS (D70-D77)

D70 Agranulocytosis

Agranulocytic tonsillitis. Children's genetic agranulocytosis. Kostmann's disease
Neutropenia:
. NOS
. congenital
. cyclic
. medicinal
. periodic
. splenic (primary)
. toxic
Neutropenic splenomegaly
If it is necessary to identify the drug causing the neutropenia, use an additional external cause code (class XX).
Excludes: transient neonatal neutropenia (P61.5)

D71 Functional disorders of polymorphonuclear neutrophils

Defect of the cell membrane receptor complex. Chronic (children's) granulomatosis. Congenital dysphagocytosis
Progressive septic granulomatosis

D72 Other white blood cell disorders

Excludes: basophilia (D75.8)
immune disorders (D80-D89)
Neutropenia (D70)
preleukemia (syndrome) (D46.9)

D72.0 Genetic abnormalities of leukocytes.
Anomaly (granulation) (granulocyte) or syndrome:
. Aldera
. May-Hegglina
. Pelguera-Huet
Hereditary:
. leukocyte
. hypersegmentation
. hyposegmentation
. leukomelanopathy
Excluded: Chediak-Higashi (-Steinbrink) syndrome (E70.3)
D72.1 Eosinophilia.
Eosinophilia:
. allergic
. hereditary
D72.8 Other specified white blood cell disorders.
Leukemoid reaction:
. lymphocytic
. monocytic
. myelocytic
Leukocytosis. Lymphocytosis (symptomatic). Lymphopenia. Monocytosis (symptomatic). Plasmacytosis
D72.9 White blood cell disorder, unspecified

D73 Diseases of the spleen

D73.0 Hyposplenism. Postoperative asplenia. Atrophy of the spleen.
Excludes: asplenia (congenital) (Q89.0)
D73.1 Hypersplenism
Excluded: splenomegaly:
. NOS (R16.1)
.congenital (Q89.0)
D73.2 Chronic congestive splenomegaly
D73.3 Spleen abscess
D73.4 Spleen cyst
D73.5 Splenic infarction. Splenic rupture is non-traumatic. Torsion of the spleen.
Excludes: traumatic splenic rupture (S36.0)
D73.8 Other diseases of the spleen. Splenic fibrosis NOS. Perisplenitis. Splenitis NOS
D73.9 Disease of the spleen, unspecified

D74 Methemoglobinemia

D74.0 Congenital methemoglobinemia. Congenital deficiency of NADH-methemoglobin reductase.
Hemoglobinosis M [Hb-M disease]. Hereditary methemoglobinemia
D74.8 Other methemoglobinemias. Acquired methemoglobinemia (with sulfhemoglobinemia).
Toxic methemoglobinemia. If it is necessary to identify the cause, use an additional external cause code (class XX).
D74.9 Methemoglobinemia, unspecified

D75 Other diseases of the blood and hematopoietic organs

Excludes: swollen lymph nodes (R59. -)
hypergammaglobulinemia NOS (D89.2)
lymphadenitis:
. NOS (I88.9)
. spicy (L04. -)
. chronic (I88.1)
. mesenteric (acute) (chronic) (I88.0)

D75.0 Familial erythrocytosis.
Polycythemia:
. benign
. family
Excludes: hereditary ovalocytosis (D58.1)
D75.1 Secondary polycythemia.
Polycythemia:
. acquired
. related to:
. erythropoietins
. decreased plasma volume
. height
. stress
. emotional
. hypoxemic
. nephrogenic
. relative
Excluded: polycythemia:
. newborn (P61.1)
. true (D45)
D75.2 Essential thrombocytosis.
Excludes: essential (hemorrhagic) thrombocythemia (D47.3)
D75.8 Other specified diseases of the blood and hematopoietic organs. Basophilia
D75.9 Disease of the blood and hematopoietic organs, unspecified

D76 Selected diseases involving lymphoreticular tissue and the reticulohistiocytic system

Excludes: Letterer-Sieve disease (C96.0)
malignant histiocytosis (C96.1)
reticuloendotheliosis or reticulosis:
. histiocytic medullary (C96.1)
. leukemic (C91.4)
. lipomelanotic (I89.8)
. malignant (C85.7)
. non-lipidic (C96.0)

D76.0 Langerhans cell histiocytosis, not elsewhere classified. Eosinophilic granuloma.
Hand-Schueller-Crisgen disease. Histiocytosis X (chronic)
D76.1 Hemophagocytic lymphohistiocytosis. Familial hemophagocytic reticulosis.
Histiocytoses from mononuclear phagocytes other than Langerhans cells, NOS
D76.2 Hemophagocytic syndrome associated with infection.
If it is necessary to identify an infectious pathogen or disease, an additional code is used.
D76.3 Other histiocytosis syndromes. Reticulohistiocytoma (giant cell).
Sinus histiocytosis with massive lymphadenopathy. Xanthogranuloma

D77 Other disorders of the blood and hematopoietic organs in diseases classified elsewhere.

Splenic fibrosis in schistosomiasis [bilharzia] (B65. -)

SELECTED DISORDERS INVOLVING THE IMMUNE MECHANISM (D80-D89)

Includes: defects in the complement system, immunodeficiency disorders, excluding disease,
caused by human immunodeficiency virus [HIV] sarcoidosis
Excludes: autoimmune diseases (systemic) NOS (M35.9)
functional disorders of polymorphonuclear neutrophils (D71)
human immunodeficiency virus [HIV] disease (B20-B24)

D80 Immunodeficiencies with predominant antibody deficiency

D80.0 Hereditary hypogammaglobulinemia.
Autosomal recessive agammaglobulinemia (Swiss type).
X-linked agammaglobulinemia [Bruton] (with growth hormone deficiency)
D80.1 Nonfamilial hypogammaglobulinemia. Agammaglobulinemia with the presence of B-lymphocytes carrying immunoglobulins. General agammaglobulinemia. Hypogammaglobulinemia NOS
D80.2 Selective immunoglobulin A deficiency
D80.3 Selective deficiency of immunoglobulin G subclasses
D80.4 Selective immunoglobulin M deficiency
D80.5 Immunodeficiency with elevated levels of immunoglobulin M
D80.6 Insufficiency of antibodies with close to normal levels of immunoglobulins or with hyperimmunoglobulinemia.
Antibody deficiency with hyperimmunoglobulinemia
D80.7 Transient hypogammaglobulinemia in children
D80.8 Other immunodeficiencies with a predominant antibody defect. Kappa light chain deficiency
D80.9 Immunodeficiency with predominant antibody defect, unspecified

D81 Combined immunodeficiencies

Excludes: autosomal recessive agammaglobulinemia (Swiss type) (D80.0)

D81.0 Severe combined immunodeficiency with reticular dysgenesis
D81.1 Severe combined immunodeficiency with low T- and B-cell counts
D81.2 Severe combined immunodeficiency with low or normal B-cell counts
D81.3 Adenosine deaminase deficiency
D81.4 Nezelof syndrome
D81.5 Purine nucleoside phosphorylase deficiency
D81.6 Deficiency of class I molecules of the major histocompatibility complex. Naked lymphocyte syndrome
D81.7 Deficiency of class II molecules of the major histocompatibility complex
D81.8 Other combined immunodeficiencies. Biotin-dependent carboxylase deficiency
D81.9 Combined immunodeficiency, unspecified. Severe combined immunodeficiency disorder NOS

D82 Immunodeficiencies associated with other significant defects

Excludes: ataxic telangiectasia [Louis-Bart] (G11.3)

D82.0 Wiskott-Aldrich syndrome. Immunodeficiency with thrombocytopenia and eczema
D82.1 DiGeorge syndrome. Pharyngeal diverticulum syndrome.
Thymus gland:
. alymphoplasia
. aplasia or hypoplasia with immune deficiency
D82.2 Immunodeficiency with dwarfism due to short limbs
D82.3 Immunodeficiency due to a hereditary defect caused by the Epstein-Barr virus.
X-linked lymphoproliferative disease
D82.4 Hyperimmunoglobulin E syndrome
D82.8 Immunodeficiency associated with other specified significant defects
D 82.9 Immunodeficiency associated with significant defect, unspecified

D83 Common variable immunodeficiency

D83.0 General variable immunodeficiency with predominant abnormalities in the number and functional activity of B cells
D83.1 General variable immunodeficiency with a predominance of disorders of immunoregulatory T cells
D83.2 Common variable immunodeficiency with autoantibodies to B or T cells
D83.8 Other common variable immunodeficiencies
D83.9 Common variable immunodeficiency, unspecified

D84 Other immunodeficiencies

D84.0 Lymphocyte functional antigen-1 defect
D84.1 Defect in the complement system. C1 esterase inhibitor deficiency
D84.8 Other specified immunodeficiency disorders
D84.9 Immunodeficiency, unspecified

D86 Sarcoidosis

D86.0 Pulmonary sarcoidosis
D86.1 Sarcoidosis of the lymph nodes
D86.2 Sarcoidosis of the lungs with sarcoidosis of the lymph nodes
D86.3 Sarcoidosis of the skin
D86.8 Sarcoidosis of other specified and combined localizations. Iridocyclitis in sarcoidosis (H22.1).
Multiple cranial nerve palsies in sarcoidosis (G53.2)
Sarcoid:
. arthropathy (M14.8)
. myocarditis (I41.8)
. myositis(M63.3)
Uveoparotitic fever [Herfordt's disease]
D86.9 Sarcoidosis, unspecified

D89 Other disorders involving the immune mechanism, not elsewhere classified

Excludes: hyperglobulinemia NOS (R77.1)
monoclonal gammopathy (D47.2)
non-engraftment and graft rejection (T86. -)

D89.0 Polyclonal hypergammaglobulinemia. Hypergammaglobulinemic purpura. Polyclonal gammopathy NOS
D89.1 Cryoglobulinemia.
Cryoglobulinemia:
. essential
. idiopathic
. mixed
. primary
. secondary
Cryoglobulinemic(s):
. purpura
. vasculitis
D89.2 Hypergammaglobulinemia, unspecified
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
D89.9 Disorder involving the immune mechanism, unspecified. Immune disease NOS