What is tetracycline tablets 100 mg for? Tetracycline tablets: instructions for use, use of tetracycline. Daily and single dosage of tetracycline for children

Tetracycline ® is a natural antibiotic of the tetracycline group. The product has a wide spectrum of antimicrobial effects, but it also has a high risk of developing secondary resistance in bacteria and frequent undesirable effects from use.

Tetracycline has a pronounced bacteriostatic effect on pathogenic microorganisms, realized by suppressing protein synthesis by bacterial cells.

The activity of tetracycline extends to most gram-, gram+ bacteria, spirochetes, leptospira, rickettsia, some large viruses and protozoa.

Tetracycline tablets are absorbed by 65-75% after oral administration. At the same time, bioavailability when taken on an empty stomach is significantly higher than when consumed during meals or immediately after a meal.

The antibiotic binds well to plasma proteins and accumulates in tissues and organs in high concentrations; tetracycline is also detected in biological fluids (bile, ascitic, synovial, etc.) in significant bacteriostatic dosages.

Tetracycline penetrates the blood-brain barrier poorly, however, with meningitis, the antibiotic accumulates in significant quantities in the membranes of the brain and cerebrospinal fluid.

Also, the antibacterial agent is able to penetrate tumor tissues and accumulate in them in large doses.

A significant amount of the antimicrobial agent penetrates bone tissue and teeth; therefore, all tetracyclines are contraindicated in children under eight years of age (the only exception is the need for post-exposure prophylaxis of anthrax). The ban on the use of tetracyclines for the treatment of patients in this age category is due to the fact that they can disrupt the formation of bone tissue and teeth, change the color of teeth and slow down the growth of bones in length.

Since the active ingredient, tetracycline, penetrates the placenta barrier well, it is strictly contraindicated during pregnancy. This is due to the highly toxic and teratogenic effects of the antibiotic on the fetus. Tetracycline can lead to significant disruption of the development of the skeleton and teeth of the fetus. It is also not used during breastfeeding (the antibiotic can pass into breast milk and be excreted with it).

When taking tetracycline, it is necessary to take into account that the antibiotic is capable of forming insoluble complexes with calcium, magnesium and aluminum, so it is not taken with milk and antacids.

The medicine does not form active metabolites in the body and is disposed of in bile and urine. Due to enterohepatic circulation (reverse intestinal absorption), tetracycline is able to circulate in the body for a long time.

Pharmacological group of tetracycline ®

Tetracycline antibiotics.

Composition and release form tetracycline ®

Tetracycline hydrochloride tablets are sold in packs of 20 tablets, the antibiotic content in each tablet is 100 milligrams.

The antibiotic is produced in the form of tablets, eye ointment and skin ointment.

The cost of Russian-made tetracycline tablets is:

• Biokhimik ® Saransk -60 rubles;
• Biosynthesis ® – 80 rubles.

Tetracycline ointment:

• Tatkhimpharmpreparaty ® (eye ointment, 3 and 5 grams) - 45 and 75 rubles;
• Biosynthesis (skin ointment) -40 rubles.

Tetracycline ® prescription in Latin

Rp: Tetracyclini 0.1.

D.t. d. N 20 in tab.

S. 0.25 - 4 times a day after meals.

What does tetracycline ® help with?

The antibiotic is active against staphylococci (including strains capable of producing penicillinase), some streptococci, listeria, anthrax, clostridia, actinomycetes, Haemophilus influenzae, mycoplasma, chlamydia, pertussis, enterobacter, Escherichia coli, Klebsiella, salmonella, Shigella, Yersi niy, Vibrio cholerae, rickettsia, Brucella (in combination with streptomycin preparations).

If the patient is intolerant to penicillin drugs, tetracycline can be used for infections caused by gonococci, clostridia, and actinomycetes.

It can also be prescribed for the treatment of syphilis (effective against white treponema), inguinal and lymphogranuloma venereum.

Almost all beta-hemolytic streptococci of group A are resistant to the antibiotic, so tetracycline is not recommended for streptococcal angina.

Also, the medicine is not effective against pseudomonads, Proteus, serrations, bacteroides, and pneumococci.

Indications for use of tetracycline ®

An antibiotic can be used to treat infectious diseases:

• respiratory tract (tetracycline can be used for and caused by chlamydia, mycoplasma, Klebsiella and Haemophilus influenzae, and can also be used for);
• MPV (if the sensitivity of the pathogen is confirmed, tetracycline can be used in complex therapy);
• skin and pancreas (can be used to treat severe forms, as well as soft tissue infections);
  endocardium (caused by endocarditis that is sensitive to tetracycline);
• Gastrointestinal tract (dysentery, intestinal amebiasis, etc.).

Tetracycline can also be used to treat actinomycosis, brucellosis, anthrax (including the need for post-exposure prophylaxis), conjunctivitis, trachoma, gingivitis, stomatitis, pharyngitis, Rocky Mountain spotted fever, Q fever, syphilis, gonorrhea (if the pathogen is sensitive), tularemia, dysentery , typhus and relapsing fever, inguinal and venereal lymphogranulomata.

In some cases, it can be used to prevent postoperative complications.

For the treatment of severe diseases with a high risk of developing septic complications, tetracycline can be used in combination with other antibacterial agents.

For angina, tetracycline is currently not recommended for use due to the high level of resistance of group A beta-hemolytic streptococci to the antibiotic.

Contraindications to the use of tetracycline ®

The antibiotic is not prescribed to children under eight years of age and to patients with:

• individual intolerance to tetracycline drugs;
• impaired renal and/or liver function.

With caution, if absolutely necessary, an antibacterial agent can be used to treat patients with leukopenia.

An additional limitation to the use of tetracycline can be considered a significant increase in resistance to the drug. In this regard, the drug began to be used much less frequently than modern semi-synthetic analogs of tetracycline of the new generation (among modern tetracyclines, doxycycline-Unidox Solutab ® is most often used; minocycline ® preparations can also be used). Modern analogs are much easier to tolerate, are less likely to cause side effects from use, and resistance to them is less likely to develop.

Tetracycline ® during pregnancy and breastfeeding

Due to the fact that the antibiotic largely penetrates the placenta, and also has a pronounced embryotoxic and teratogenic effect on the fetus and can lead to the formation of congenital malformations (in particular, tetracycline leads to disruption of the formation of the baby’s skeleton and teeth), tetracycline is strictly contraindicated in pregnant women women.

Considering that the antibiotic can penetrate into breast milk and be excreted with it, it is also not used during breastfeeding. If the mother needs to take tetracycline, breastfeeding is stopped and the child is transferred to artificial feeding.

Dosage, method of use tetracycline ®

Tetracycline tablets should be taken with plenty of water.

For patients over eight years of age, the antibiotic is prescribed in a daily dose of 20 to 25 milligrams per kilogram of body weight, divided into four doses (every six hours). For adults, it is recommended to take 0.25 to 0.5 grams four times a day.

For the treatment of acne, tetracycline is prescribed in a daily dose of 500 to 2000 milligrams (depending on the severity of the disease), divided into two or four doses, with a gradual reduction in the dose to a maintenance dose (from 125 to 1000 milligrams), usually after three weeks. Further, an intermittent course or use of an antibiotic every other day may be indicated.

To treat brucellosis, the antibacterial agent is used in a daily dose of 2 grams (divided into 4 doses) for three weeks, in combination with streptomycin (intravenously) 1 gram twice a day for a week, and once a day for the remaining two weeks.

For uncomplicated forms of gonorrhea, the antibiotic can be used in an initial single dosage of 1500 milligrams, and then 500 milligrams four times a day for another four days.

For uncomplicated urethral infections of chlamydial etiology, as well as prostatitis, tetracycline can be used at a dose of 500 mg every six hours.

The duration of treatment is determined by the attending physician.

Side effects of tetracycline ®

Taking an antibiotic can lead to intestinal dysbiosis, dyspeptic disorders, abdominal pain, thrush, increased intracranial pressure, dizziness, loss of coordination, increased sensitivity to sunlight, the appearance of skin pigmentation, discoloration of tooth enamel, hypovitaminosis of B vitamins, allergic reactions, drug-induced pancreatitis, hepatitis, kidney damage.

Alcohol compatibility

Tetracycline preparations are incompatible with alcohol. Drinking alcohol significantly reduces the antibacterial activity of tetracycline and increases the load on the liver.

Tetracycline ® analogues

• Tetracycline ® is available under the trade names:
• Tetracycline-AKOS ® ;
• Tetracycline-Teva ® ;
• Tetracycline hydrochloride ® ;
• Tetraolean ® (combination drug with the macrolide oleandomycin);
• Oletetrin ® (combination drug with the macrolide oleandomycin);
• Polcortolone ® (aerosol with the synthetic glucocorticosteroid triamcinol);
• Imex ® (skin ointment).

Modern analogues:

• Minocycline ® ;

Tetracycline tablets ® - reviews

Due to the increasing resistance of microorganisms, the use of antibiotics is currently limited. However, tetracycline has positive reviews from doctors and patients in the treatment of severe forms of acne (new generation tetracycline analogues can also be used).

It is also noted that tetracycline remains highly effective against cholera, brucellosis, tularemia, inguinal and venereal lymphogranulomata.

Tetracycline is a bacteriostatic antibiotic. Instructions for use indicate that 100 mg tablets, 3% ointment for external use and 1% ocular ointment have a wide spectrum of antibacterial action. According to experts, this medication helps in the treatment of bronchitis, pneumonia, acne (pimples), blepharitis and conjunctivitis.

Release form and composition

Tetracycline is available in the following dosage forms:

1. film-coated tablets: pink, round, biconvex;
2. ointment for external use 3%: yellow, homogeneous (10 g or 15 g in aluminum tubes, one tube in a cardboard box);
3. eye ointment 1%: yellowish or yellowish-brown in color, homogeneous (2, 3, 5 or 10 g in aluminum tubes, one tube in a cardboard box).

Tetracycline tablets are packaged in blister packs of 20 pieces. The cardboard box contains 1 blister of tablets, as well as instructions for use of the drug.

Tablet composition: active ingredient: tetracycline – 0.1 g; auxiliary components: basic magnesium carbonate, calcium stearate, corn starch, gelatin, sucrose, tropeolin O, talc, dextrin, acid red dye 2C.

Composition of 1 g ointment for external use: active ingredient: tetracycline – 0.03 g; auxiliary components: ceresin, petroleum jelly, solid petroleum paraffin, sodium metabisulfite, anhydrous lanolin.

Composition per 1 g of eye ointment: active ingredient: tetracycline – 0.01 g; auxiliary components: petroleum jelly, anhydrous lanolin.

pharmachologic effect

Tetracycline is a broad-spectrum antibiotic. It has a bacteriostatic effect by suppressing the protein synthesis of pathogens. Active against aerobic gram-positive and gram-negative bacteria, anaerobic bacteria.

Also active against Rickettsia spp., Chlamydia spp., Mycoplasma spp., Spirochaetaceae. Pseudomonas aeruginosa, Proteus spp., Serratia spp., most strains of Bacteroides fragilis, most fungi, and small viruses are resistant to tetracycline.

Indications for use

What does Tetracycline help with? Indications for the use of this drug are as follows:

• endometritis;
• prostatitis;
• pneumonia, tracheitis, bronchitis, pleural empyema;
• pyelonephritis;
• syphilis, gonorrhea;
• tonsillitis, pharyngitis, otitis media;
• rickettsial diseases;
• whooping cough;
• furunculosis, acne, infected eczema, folliculitis;
• conjunctivitis, blepharitis;
• purulent soft tissue infections;
• cholecystitis;
• intestinal infections;
• trachoma;
• endocarditis;
• osteomyelitis;
• brucellosis.

Of the listed diseases, eye ointment is used, and tablets are used to treat serious infectious diseases. For which ointment can be used in each individual case, it is advisable to consult a doctor. It is often prescribed instead of eye drops.

Regarding Tetracycline tablets (for what and in what dose to use), it is also better to consult a specialist. In some cases it is prescribed, for example, for sore throat. In addition, experts sometimes recommend using Tetracycline for acne.

Instructions for use

Prescribed orally for adults - 250-500 mg every 6 hours. Children over 8 years old - 25-50 mg/kg every 6 hours. The maximum daily dose for adults when taken orally is 4 g.

• acne: 0.5–2 g per day in several doses. When the condition improves, which is observed after about 3 weeks, the dose of the drug is gradually reduced to a maintenance dose of 0.125–1 g per day. Adequate remission of the disease can be obtained by using tetracycline every other day or with intermittent treatment;
• uncomplicated endocervical, rectal and urethral infections caused by Chlamydia trachomatis: 0.5 g four times a day, course of treatment - at least 7 days;
• brucellosis: 0.5 g four times a day (every 6 hours) for 3 weeks; during the first week, intramuscular injections of streptomycin are additionally performed (1 g twice a day), during the second week streptomycin is administered once a day;
• syphilis: 0.5 g four times a day, the course of treatment is 15 (for early syphilis) or 30 (for late syphilis) days;
• uncomplicated gonorrhea: the initial dose is 1.5 g per day, then the drug is administered at 0.5 g four times a day for 4 days.

Ointment

Apply externally several times a day; if necessary, apply a loose bandage. Locally - 3-5 times a day.

Eye ointment 1%

Tetracycline in the form of an eye ointment is used topically. The drug is placed behind the eyelid. A single dose is a strip of ointment 0.5–1 cm long.

For trachoma, ointment is applied every 2–4 hours or more often for 1–2 weeks. With a decrease in inflammation, the frequency of use of Tetracycline is reduced to 2-3 times a day. The general course of treatment is 1–2 months. For blepharoconjunctivitis and blepharitis, the ointment is used 3-4 times a day. The course of treatment is 5–7 days.

For keratoconjunctivitis and keratitis, the frequency of use of the drug is 2–3 times a day, and the course of treatment is 5–7 days. If there is no improvement on the 3rd–5th day of therapy, you should consult a doctor.

For barley, eye ointment is applied at night. The duration of the course is until the signs of inflammation disappear.

Contraindications

In several pathological or physiological conditions of the patient’s body, taking Tetracycline tablets is contraindicated, these include:

• Pregnancy at any stage, as well as the period of breastfeeding (lactation period).
• Marked decrease in the functional activity of the liver or kidneys.
• Decrease in the number of white blood cells (leukopenia) in the blood.
• Systemic lupus erythematosus (autoimmune pathology).
• The patient's age is less than 12 years.
• Individual intolerance to tetracycline or auxiliary components of this drug.
• Mycoses (fungal infections) of various localizations in the body.

Before prescribing Tetracycline tablets, the doctor must rule out possible contraindications for the patient.

Side effects

Possible adverse reactions:

• CNS: headache, increased HF pressure, dizziness;
• allergies and immunopathological reactions: skin hyperemia, angioedema, maculopapular rash, systemic lupus erythematosus, anaphylactoid reactions, photosensitivity;
• urinary system: azotemia, hypercreatininemia;
• hematopoietic organs: hemolytic anemia, neutropenia, thrombocytopenia, eosinophilia;
• organs of the digestive system: dysphagia, increased sensitivity of the papillae of the tongue, dullness of hunger, diarrhea, glossitis, gastritis, hepatotoxic effect, pancreatitis, enterocolitis, vomiting, nausea, esophagitis, gastric and duodenal ulcers, increased activity of liver transaminases, dysbacteriosis;
• other: superinfection, hypovitaminosis B, discoloration of the enamel of baby teeth, candidiasis, stomatitis.

Children, pregnancy and breastfeeding

Tetracycline is contraindicated during pregnancy and lactation. Penetrates through the placental barrier. May cause long-term discoloration of teeth, enamel hypoplasia, and suppression of fetal skeletal bone growth. In addition, tetracycline can cause the development of fatty liver.

special instructions

During treatment with Tetracycline, it is necessary to limit insolation, as photosensitivity may develop. With long-term use of the drug, the function of the liver, kidneys and hematopoietic organs should be periodically monitored.

Tetracycline can mask the symptoms of syphilis, so if a mixed infection is likely, a serological test should be performed monthly (for 4 months). In children, during the period of tooth development, enamel hypoplasia and long-term staining of tooth enamel in a yellow-gray-brown color are possible.

This effect is due to the fact that tetracyclines interact with calcium and form stable complexes with it in any bone-forming tissue. To prevent hypovitaminosis during treatment with Tetracycline, it is advisable to additionally take brewer's yeast, vitamin K and B vitamins.

Drug interactions

The degree of absorption of the drug decreases when taking antacids, which include aluminum, calcium and magnesium, as well as medicines with iron and cholestyramine.

The use of the drug also reduces the effect of bactericidal antibiotics that interfere with cell wall synthesis.

Combination with Chymotrypsin leads to an increase in the active substance of Tetracycline and the duration of circulation.

The drug reduces the effect of estrogen-containing oral contraceptives and increases the likelihood of breakthrough bleeding. In combination with Retinol, the risk of increased intracranial pressure increases.

Analogues of the drug Tetracycline

Analogues are determined by structure:

1. Tetracycline-AKOS.
2. Tetracycline hydrochloride.
3. Tetracycline-LecT.

Vacation conditions and price

The average cost of Tetracycline (100 mg tablets No. 20) in Moscow is 58 rubles. Dispensed by prescription.

Store in a dry, dark place at a temperature not exceeding 15 C (eye ointment), 20 C (ointment for external use) or 25 C (coated tablets). Keep away from children. Shelf life – 3 years.

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Tetracycline is one of the most famous antibiotics. It began to be used a long time ago, but at the same time it is still relevant. It is mainly used for diseases affecting the digestive system.

Release form and mechanism of action

Tetracycline is produced in the form of film-coated tablets of 500, 250 and 125 mg.

Tetracycline is a broad-spectrum antibiotic. It inhibits protein synthesis in the bacterial cell, thereby stopping its growth.

The drug is effective against the following microorganisms:

• Gram-negative: Haemophilus influenzae, Klebsiella, the causative agent of borreliosis and brucellosis;
• Gram-positive: streptococcus, staphylococcus (including aureus), to the causative agents of anthrax and actinomycosis.

Indications for use

The drug is used in the following cases:

• (inflammation of the gallbladder);
• Urinary tract diseases;
• Diseases of the lower and upper respiratory tract;
• Subacute septic endocarditis (inflammation of the internal cavities of the heart);
• For diseases that are transmitted to humans from animals (tularemia, typhus and relapsing fever);
• To prevent complications during surgical interventions;
• For the treatment of diseases of the genitourinary system (including gonorrhea);
• The drug is also used to treat amoebic and bacterial dysentery, scarlet fever, whooping cough, trachoma, plague, and granuloma inguinale.

Directions for use and dosage

The tablets are taken orally, without chewing, half an hour or an hour before meals, with a sufficient amount of water.

Adults are prescribed 250 mg of the drug every 6 hours. The maximum daily dose is 2 g.

Side effects

• From the immune system: urticaria, anaphylactic shock, rash, itching, redness of the skin, angioedema, increased sensitivity to sunlight, possible development of systemic lupus erythematosus;
• From the liver: disruption of its function, hyperbilirubinemia, increased activity of liver transaminases;

If side effects occur, consult a doctor!

From the nervous system: increased intracranial pressure, cephalgia, dizziness;

• From the digestive system:, decreased appetite, changes in the mucous membranes of the gastrointestinal tract and mouth (, stomatitis, glossitis);
• Blood disorders: anemia, leukopenia, thrombocytopenia;
• From the genitourinary system: impaired renal function;
• Other effects: administration of the drug during the formation of teeth can cause a change in the color of their enamel. With prolonged use of Tetracycline, fungal diseases may occur.

Contraindications

• With increased sensitivity to Tetracycline and antibiotics of this series;
• It should also not be used in cases of severe renal and liver dysfunction;
• With leukopenia;
• Tetracycline is not prescribed to children under 8 years of age;
• During breastfeeding and pregnancy.

Interaction with other drugs

• You should not take Tetracycline simultaneously with drugs containing metal ions (calcium, manganese, magnesium, zinc, aluminum), since their mutual absorption decreases;
• When taken simultaneously with carbamazepine and barbiturates, the antimicrobial activity of Tetracycline is impaired;
• Combination with antibiotics from the group of penicillins and cephalosporins should be avoided;
• The drug can be combined with Streptomycin;
• It is prescribed with caution with drugs for the treatment of diabetes.

special instructions

Tetracycline is a broad-spectrum antibiotic with a bacteriostatic effect.

Bacteriostatic antibiotic from the tetracycline group. It disrupts the formation of a complex between transfer RNA and the ribosome, which leads to suppression of protein synthesis.

Active regarding:

• gram-positive microorganisms: Staphylococcus spp. (including Staphylococcus aureus, including penicillinase-producing strains), Streptococcus spp. (including Streptococcus pneumoniae), Listeria spp., Bacillus anthracis, Clostridium spp., Actinomyces israelii;
• gram-negative microorganisms: Haemophilus influenzae, Haemophilus ducreyi, Bordetella pertussis, most enterobacteria: Escherichia coli, Enterobacter spp., including Enterobacter aerogenes, Klebsiella spp., Salmonella spp., Shigella spp., Yersinia pestis, Bartonella bacilliformis, Vibrio cholerae, Vibrio fetus, Rickettsia spp., Borrelia burgdorferi, Brucella spp. (in combination with ).

Microorganisms resistant to tetracycline: Pseudomonas aeruginosa, Proteus spp., Serratia spp., most strains of Bacteroides spp. and fungi, viruses, group A beta-hemolytic streptococci (including 44% of Streptococcus pyogenes strains and 74% of Streptococcus faecalis strains).

After oral administration, up to 66% of the dose taken is absorbed. Binds to plasma proteins by 65%. Penetrates well into various organs and tissues, as well as biological fluids: bile, synovial, ascitic fluid, CSF (in the latter the concentration is 10–25% of that in blood plasma), accumulates in bone tissue and teeth, liver, spleen, tumors. Penetrates through the placenta and into breast milk. Not metabolized, excreted in urine and bile.

Indications for use

What do Tetracycline tablets help with? According to the instructions, the drug is prescribed for the treatment of infectious and inflammatory diseases caused by microorganisms sensitive to tetracycline:

• pneumonia, tracheitis, bronchitis, pleural empyema;
• purulent soft tissue infections;
• pyelonephritis;
• endocarditis;
• prostatitis;
• whooping cough;
• rickettsial diseases;
• osteomyelitis;
• furunculosis, acne, infected eczema, folliculitis;
• cholecystitis;
• intestinal infections;
• endometritis;
• syphilis, gonorrhea;
• trachoma;
• brucellosis;
• tonsillitis, pharyngitis, otitis media;
• acne (pimples).

The drug is also used to prevent postoperative infectious complications in surgery.

Instructions for use Tetracycline, tablet dosage

The tablets are intended for oral administration. They are taken 1 hour before meals or 2 hours after meals, not chewed and washed down with a sufficient amount of water.

According to the instructions for use, Tetracycline tablets are prescribed in dosages of 250-500 mg 4 times a day or 500 mg - 1 gram 2 times a day. The maximum dosage is 4 grams per day.

For children, Tetracycline is used depending on the child’s body weight - at the age of 8–18 years, tablets are prescribed at 6.25–12.5 mg/kg body weight\ 4 times a day or at 12.5–25 mg/kg body weight\ 2 times a day.

The average duration of therapy varies between 7-10 days. The doctor prescribes the dosage, regimen and duration of the course of therapy individually.

special instructions

During treatment with Tetracycline, it is necessary to limit insolation, as photosensitivity may develop.

With long-term use of the drug, the function of the liver, kidneys and hematopoietic organs should be periodically monitored.

The instructions warn that Tetracycline can mask the symptoms of syphilis - if there is a possibility of a mixed infection, a serological test must be performed monthly (for 4 months).

To prevent hypovitaminosis while using Tetracycline tablets, it is advisable to additionally take brewer's yeast, vitamin K and B vitamins.

Side effects

The instructions warn about the possibility of developing the following side effects when prescribing Tetracycline:

• From the digestive system: nausea, vomiting, anorexia, abdominal pain, diarrhea, constipation, dry mouth, glossitis, discoloration of the tongue, esophagitis, transient increase in the activity of liver transaminases, alkaline phosphatase, bilirubin concentration, residual nitrogen.
• From the side of the central nervous system: dizziness, headache.
• From the hematopoietic system: neutropenia, thrombocytopenia, hemolytic anemia.
• Allergic reactions: skin rash, itching, eosinophilia, Quincke's edema.
• Dermatological reactions: photosensitivity.
• Effects caused by chemotherapeutic action: candidal stomatitis, vulvovaginal candidiasis, intestinal dysbiosis.
• Other: hypovitaminosis of B vitamins.

Contraindications

It is contraindicated to prescribe Tetracycline tablets in the following cases:

• Hypersensitivity to tetracycline;
• Impaired liver and kidney function;
• During pregnancy and breastfeeding;
• Leukopenia;
• Mycoses (fungal infections);
• Systemic lupus erythematosus;
• Age up to 8 years.

In this case, after preliminary lavage of the stomach and intestines, as well as taking intestinal sorbents (activated carbon), symptomatic therapy is carried out in a medical hospital, since there is no specific antidote.

Analogues of Tetracycline tablets, price in pharmacies

If necessary, you can replace Tetracycline with an analogue of the active substance - these are the following drugs:

• Glycocycline,
• Imex,
• Tetracycline-AKOS and Tetracycline-LekT,
• Tetracycline hydrochloride.

When choosing analogues, it is important to understand that the instructions for use of Tetracycline tablets, price and reviews do not apply to drugs with similar effects. It is important to consult a doctor and not change the drug yourself.

Price in Russian pharmacies: Tetracycline tablets 100 mg 20 pcs. – from 51 to 72 rubles, Tetracycline with Nystatin 0.1+0.0222 10 tablets – from 59 to 81 rubles, according to 309 pharmacies.

Store in a dry, dark place at 25 °C. Keep away from children. Shelf life – 3 years.

Dispensing conditions from pharmacies are by prescription.

Antibiotic therapy is a common practice to eliminate pathogenic microorganisms. Most antibiotics with an improved pharmacological formula allow you to get rid of several types of microbes at once, without causing significant harm to the body.

Pharmacological activity

Tetracycline is a broad-spectrum antibiotic from the tetracycline group. The WHO Model List of Essential Medicines contains information about this antibacterial substance as one of the most important medicinal products. The list was compiled by experts from the World Health Organization.

Tetracycline tablets help against a number of diseases. The bacteriostatic effect is formed due to disruption of the formation of the complex between transport type RNA and the ribosome. The antibiotic helps eliminate gram-positive microorganisms:

Gram-negative life forms are also sensitive to the drug. Main representatives: Haemophilus influenzae, Haemophilus ducreyi, Bordetella pertussis, enterobacteria (Escherichia collie).

If the patient cannot tolerate the penicillin series of drugs, tetracycline is offered as an alternative.

Resistant to popular antibacterial agents: Pseudomonas aeruginosa, Proteus spp., Serratia spp., group A streptococci, viruses, fungal invasions.

Indications for antibiotic use

Tablets are prescribed extremely often. A wide range of influences and pronounced accessibility of the drug allow us to work with patients of different age groups suffering from various diseases. Main indications:

Tetracycline tablets help if the patient is prohibited from taking penicillin drugs. The analogue is relevant for the following forms of pathologies: syphilis, necrotizing gingivitis, anthrax, actinomycosis.

Possible contraindications

Antibiotic therapy helps get rid of pathogenic microorganisms, but the selection of drugs is sometimes associated with a number of difficulties. The highly effective and versatile antibiotic tetracycline cannot always be used. Main contraindications:

You should take an antibiotic with extreme caution if you have a history of allergic reactions. A preliminary consultation with the attending physician is recommended for adult patients. Self-medication is strictly prohibited.

Directions for use, key aspects of dosage

Tetracycline hydrochloride in tablet form is taken 1 hour before or 2 hours after meals. Take the tablet with plenty of liquid. Recommended dosages:

To eliminate inflamed pimples and in the fight against acne, 500 - 2000 mg/day is prescribed. Doses are divided. The maximum daily dose of the antibacterial drug is 4000 mg.

Increasing the recommended parameters is strictly prohibited.

Children over 8 years of age are prescribed the drug, and the dose is clearly calculated. Every 6 hours, 6.25-12.5 mg/kg is administered. After a course of antibiotic therapy, it is necessary to conduct a thorough examination of the child.

Side effects

How much to take the drug is decided solely by the attending physician, focusing on the characteristics of the patient’s body and the specifics of the problems that need to be dealt with. It is important to choose the minimum dose of the drug at which the maximum effect would be observed.

Such a clear calculation of the dose is important, since there is always a risk of side effects. And they usually arise against the background of an ill-chosen regimen for taking medicinal products. For long-term therapy, tetracycline lect is recommended to be supplemented with antifungal agents (for example, taken with nystatin). Main side effects:

By the way, tetracycline antibiotics are widely used in veterinary practice. They can be prescribed to a cat or dog when various infectious processes develop. The issue is resolved exclusively by the veterinarian.

Tetracycline with nystatin

Tetracycline with nystatin should be considered as a separate drug in demand in the modern pharmacological market. This is a combination product that has both antimicrobial and antifungal effects.

The main active ingredients are presented in almost the same amount, which makes the product more versatile and effective.

Pharmacological form - tablets. The medicinal product is relevant for diseases of the ENT organs, acne, pneumonia, bronchitis, otitis, cholecystitis. It is advisable to prescribe a new remedy for sexually transmitted diseases, intestinal infections, infectious processes localized in bones and joints.

Analogues of the drug

Tetracycline antibiotics are a whole range of various lyophysilates, capsules, ointments, suspensions for the total and local elimination of pathogenic microorganisms. The table shows analogues of drugs that can replace the popular tetracycline.