Modern antidepressants. Antidepressants: which ones are better. Group of tricyclic antidepressants

People who feel depressed and are unable to cope with it need help, which can be provided by certain medications, including over-the-counter antidepressants.

Strictly speaking, self-medication with antidepressants is not the best idea, because the patient cannot take into account all the factors and features pharmacological treatment what self-assignment does prescription drugs dangerous to health. But sometimes it is impossible to see a doctor for some reason, but help is still needed. What can be done in this case?

Most effective ways solutions to the problem are the support of relatives and the help of a specialist (psychologist, psychotherapist or psychiatrist, depending on the person’s condition and the cause of the illness). Apathy, indifference and lack of positive emotions are character traits depression. Sometimes it is difficult to overcome the overwhelming hopelessness, so drug treatment is required.

Each person experiences stress and depression differently. Depression can be accompanied by various manifestations:

  • irritability;
  • loss of appetite;
  • sleep disturbance;
  • anxiety;
  • apathy;
  • fear;
  • yearning;
  • tearfulness;
  • skin rashes;
  • disruption digestive system;
  • allergy.

In addition, it may appear increased sweating, tachycardia and even shortness of breath. If there are three or more signs, you should consult a doctor, who, after examination and clarification of the circumstances, will recommend which drug is most suitable.

Most psychoactive drugs should be taken according to a special regimen, dosages should be strictly observed, first gradually increasing them, then decreasing them using the same method. Many medications have a cumulative effect, requiring time for them to take effect and time for the patient to feel well without them.

But in cases where only the first signs of the disease are observed, over-the-counter antidepressants, more weak drugs with less side effects, are quite appropriate.

Important! Whether a prescription is required to use the drug or not, a strict rule must be followed - only a doctor can prescribe the drug. The doctor determines the dosage and duration of the course.

The main difference between medications that are freely dispensed in pharmacies is that they are intended for mild degree depression, or subdepression - a short-term decrease in mood.

The composition of the products may be different; they differ from each other in chemical formula, main active substances and additional components.

What they have in common is a minimal number of side effects and contraindications. As a rule, antidepressants without a doctor's prescription are based on plants. But even if the composition includes artificially synthesized chemical elements, their concentration makes the drug harmless.

Strong antidepressants without prescriptions are a myth. MAOIs, tricyclics, SOZS and other neurotransmitter retake inhibitors are not sold without a special document from a psychiatrist.

What drugs can be purchased without a prescription?

The list of such funds is quite extensive. Medicines that can lift your mood, reduce irritability, improve sleep and restore appetite are not necessarily powerful. You can change your condition for the better with the help of mild antidepressants and sedatives. plant based.

Below are the medications that are most popular.

Deprim

Herbal remedy based on St. John's wort herb extract. Additional components are stabilizers. Preservatives and fillers are intended for the production of solid dosage forms. Also contains lactose and calcium dihydrate.

The drug normalizes functionality nervous system, improves sleep and mood due to substances contained in the plant:

  1. A phloroglucinol derivative, hyperforin, is a powerful inhibitor of a group of neurotransmitters. It is a strong anxiolytic and antidepressant that activates receptor potential ion channels. In addition, the element has antibiotic properties and is active against strains of staphylococcus resistant to methicillin. It is also able to remove inflammation.
  2. Another substance, hypericin, improves the functioning of the autonomic and nervous systems. Affects dopaminergic structures, converting this hormone into norepinephrine. Thanks to the element, mild and moderate depression can be easily cured.

A significant advantage of the drug Deprim is the combination of high safety and effectiveness and low cost. The price for a pack of medicine containing two blisters of 15 tablets is 250 rubles.

It is prescribed in the following cases:

  • emotional exhaustion;
  • chronic fatigue;
  • depression;
  • weather dependence;
  • mood swings during menopause.

The composition is prescribed for oral administration. The dosage is 1-3 tablets three times a day, depending on age. The therapeutic effect is observed 10 days after the start of use. General course treatment - a month.

Contraindications for use are as follows:

  • age up to 6 years;
  • depression with suicidal tendencies;
  • intolerance to components.

In most cases, the drug is well tolerated, but if the dosage is exceeded, side effects may develop in the form of dyspeptic disorders and allergies.

Important! Deprim should not be combined with cyclosporine and theophylline. It is strictly forbidden to drink alcohol during treatment.

In addition to Deprim, drugs such as Negrustin, Gelarium and a number of others have been created based on St. John's wort. Doctors emphasize that there have been no reliable and large-scale studies on the effectiveness and side effects of these herbal medicines.

Persen

This mild antidepressant is on the list of medications most often prescribed by psychiatrists. It contains three types of plant extracts:

  • Melissa;
  • valerian;
  • peppermint.

Available in tablet form, it acts as an antispasmodic, quickly eliminates irritability and calms. In addition, the drug provides complete sleep without causing daytime drowsiness. The effectiveness of the composition is due to valerian, which contains alkaloids and essential oils. The plant relieves vasospasm and nervous excitement.

Melissa is an antispasmodic and antidepressant, which also has anxiolytic and immunomodulatory properties. The natural substance not only calms and restores a stable emotional state, but also fights viruses and germs. The plant improves appetite and helps eliminate signs of toxicosis during pregnancy.

Terpenoids and menthol, which are contained in mint, have a beneficial effect on emotional background and relieve headaches.

The leaves are used during menopause and for stress as a sedative. The substance also helps prevent anorexia, protects against infections and inflammatory processes.

Persen is indicated when there is no need to use potent drugs; it is used in the following cases:

  • neuroses;
  • when withdrawing sedatives;
  • disorders in the autonomic nervous system;
  • during menopause;
  • for the prevention of pathologies in people with poor resistance to stress.

The medicine is well tolerated, there are very few side effects. These include allergic manifestations and constipation when long-term use. It is contraindicated for the following conditions and diseases:

  • lactose and fructose intolerance;
  • the presence of stones in the gall bladder and kidneys;
  • pregnancy;
  • lactation period;
  • reduced arterial pressure.

Also not prescribed for children under 12 years of age. The dosage is 2-3 tablets in several doses per day. For insomnia, you should take the medication an hour before going to bed. The course of treatment should last no more than 90 days. The average cost of a package with 40 tablets is 300-400 rubles.

For reference! Persen can enhance the effect of antihypertensive, hypnotic and analgesic compounds, so dose adjustments are required.

Novo-Passit

This medication contains whole list medicinal herbs with different properties:

  1. Hawthorn. This plant began to be used in medical purposes back in the 16th century. It was originally intended as an astringent for diarrhea. Later, its ability to purify the blood and have a beneficial effect on blood vessels was discovered. The plant contains flavonoids and hydroxycinnamic acids, which explains its functions as a cardiotonic,
  2. St. John's wort is a natural antidepressant from the Malpighiaceae genus. This perennial shrub in extract form is effective for anxiety disorders, improves emotional well-being, and eliminates depression and depression. It is often used in therapeutic complexes for alcohol, drug and drug addiction.
  3. A plant of the passionflower family, passionflower contains glycosides, saccharides, and amino acids. It has been used in sedatives for a very long time. Helps with sleep disorders, seizures and even epilepsy. Eliminates fear and nervousness, effective for irritability. In combination with hawthorn it has an enhanced effect.
  4. Hops belong to the genus of flowering hemp plants. Contains anthocyonides, catechins, phenolcarboxylic acids. It is considered a mild sedative, which is slightly inferior to the potency of valerian. Suppresses the activation of chemical carcinogens and prevents angiogenesis. Hops also prevents the development of tumors.
  5. Medicinal essential oil herbaceous lemon balm - another natural antidepressant and anxiolytic. The plant is able to fight viruses and bacteria and protects against infections. In addition, it stimulates immune mechanisms and helps strengthen the body. The herb increases appetite and performance, improves mood.
  6. A flowering plant of the Adoxaceae family, elderberry disinfects, relieves inflammation and helps in the treatment of gout and rheumatism. The spectrum of its action is quite extensive. Elderberry copes well with pain of various etiologies, removes anxiety, fear and apathy. In addition, it is suitable for improving metabolism and treating skin pigmentation disorders.

In addition to plants, the preparation contains the main active substance– guaifenesin. This element is considered a mucolytic, which helps evacuate secretions in respiratory diseases. But in combination with herbs, it exhibits sedative properties and eliminates feelings of melancholy and depression.

Indications for the use of Novo-Passit are as follows:

  • neurasthenia;
  • migraine;
  • mental stress;
  • syndromes during menopause;
  • sleep disorders;
  • functional disorders of neuroendocrine regulation;
  • fatigue;
  • decreased performance and attention.

The list of contraindications is short. This is myasthenia gravis and intolerance to any of the components of the medication. It is also not prescribed to children under 12 years of age. Therapy for alcoholism and serious pathologies of the digestive system should be carried out under supervision.

It cannot be said that this is the cheapest drug; the cost varies between 300-330 rubles. for 300 ml of syrup and 170-200 rubles. for 10 tablets.

For reference! Novo-Passit should be taken with caution in case of epilepsy and after head injuries. In such cases, the doctor adjusts the duration and dosage regimen.

When used simultaneously with muscle relaxants, the following side effects may occur: muscle weakness. Also reduces exposure hormonal contraception, which must be taken into account when receiving.

Afobazole

This drug is more likely to be an anxiolytic with a neuroprotective effect that protects cells from damage. It has a dual effect on the nervous system. At the same time relieves anxiety and depression and stimulates memory, emotions and motor skills.

Its functions are based on that. that it prevents changes in receptors that occur during the activity of gamma-aminobutyric acid, an inhibitory neurotransmitter. The result is a sedative and muscle relaxant effect.

A distinctive feature of the medication is that, according to the manufacturer, it helps to get rid of excessive suspiciousness and uncertainty, while memory and concentration remain within normal limits.

The first result is observed already on the fifth day of treatment, and the full therapeutic effect appears after 4 weeks and lasts for another 14 days after discontinuation of the drug.

The medication is well absorbed and distributed throughout systems where it binds to protein compounds. It is also quickly eliminated from the body, which virtually eliminates complications after an overdose. Its price for 690 tablets is 350-400 rubles.

Indications for the use of Afobazole are as follows:

  • anxiety states of various etiologies;
  • mental disorders;
  • neuroses;
  • disorders of the autonomic and vascular system;
  • premenstrual syndrome;
  • menopause period;
  • alcoholism treatment;
  • irritability associated with quitting smoking.

Do not take the drug during pregnancy and lactation. Do not prescribe the medicine if you are hypersensitive to its components. It is also contraindicated for children. Adverse reactions are associated with intolerance to the substances included in the composition and are expressed in allergic manifestations and dysfunctions of the digestive system.

The optimal dosage is 10-30 mg per day, divided into three doses. The course of treatment lasts 4 weeks, but in some cases the doctor may extend it to 3 months.

If there is a need to take medicine while breastfeeding, lactation will have to be abandoned. With simultaneous consumption of alcohol, the toxic effect on brain cells increases, and the therapeutic properties of the drug are leveled.

The pharmaceutical industry offers a huge list of effective treatments for depression. If depression has just begun to manifest itself, over-the-counter antidepressants based on herbal ingredients. But even such safe compounds should be prescribed by a doctor, as they can also cause adverse reactions and have contraindications.

Important! Even with mild emotional disorders, the help of a specialist (psychotherapist or psychiatrist) should not be avoided. If the cause is not identified, taking the most effective medications will be useless or even harmful.

Many people at the slightest stressful situations they grab pills without even really understanding whether they can be taken or what will happen after that.

It is necessary to understand that anxiety states differ from neuroses, and depression differs from mental disorders. And only a doctor can deal with the patient’s problems and help eliminate them without negative consequences.

Ask an expert a question in the comments

Every second resident of the metropolis suffers from depression. To treat this disease, psychiatrists or neurologists prescribe special medicines. Many patients are interested in whether it is possible to buy strong antidepressants without a doctor's prescription. It is important to note that to purchase powerful tool appointment is mandatory, because they have a lot of contraindications. There are mild medications that can help cope with the symptoms of a nervous disorder and are available without a prescription.

Indications for the use of antidepressants

Before buying anti-depression pills without a prescription at the pharmacy, it is important to make sure that the problem requires drug therapy. Perhaps a person only needs to eliminate the factors that provoke the development of symptoms of the disease. Experts recommend reviewing your lifestyle, avoiding stress, and getting more rest before starting to take the pills. People with strong depressive disorders Over-the-counter medications are not suitable. This category of patients definitely needs specialist consultation and comprehensive treatment.

All antidepressants have side effects and contraindications, so before using them it is important to consult a neurologist or psychiatrist. The drugs have different chemical compositions, structures, and different ways of affecting the body. The same medicine can affect different patients differently, so you should not treat depression with medications yourself. Especially it concerns chronic forms mental illness.

If you need to reduce the susceptibility of the nervous system to external stimuli, you can use mild antidepressants without prescriptions. Such medications significantly improve a person’s quality of life without causing serious harm to health. They can be used for the following pathological conditions:

  • pain of an unspecified nature;
  • anorexia;
  • sleep disturbance, appetite disturbance;
  • bulimia;
  • groundless anxiety;
  • attention disorder;
  • chronic fatigue;
  • alcohol addiction;
  • irritability;
  • drug addict.

Antidepressants without a prescription, plant-based

Herbal medications for depression are considered the safest. They will help with stress, nervous exhaustion, various phobias, appetite and sleep disorders. Herbal medicines for depression without prescriptions do not have a negative effect, they have a gentle effect on the body. Before taking any tablets or capsules, you should carefully read the composition, indications, side symptoms and instructions for use.

Novo-passit

This remedy is one of the most popular antidepressants based on natural ingredients. The composition of the herbal preparation includes extracts of the following herbs:

  • hop;
  • St. John's wort;
  • hawthorn;
  • Melissa;
  • valerian.

This mild antidepressant is especially popular among office workers, for whom the state of permanent stress and continuous time pressure has become habitual. Novo-Passit helps cope with menopausal syndrome, neurocirculatory dystonia, irritability, migraine, increased nervousness, neurasthenia, and normalizes sleep. The drug provides a stable sedative effect. You can buy the Medicine in the form of tablets or syrup. The price varies from 200 to 600 rubles.

Before starting to use the drug without a prescription, it is worth studying the contraindications. These include the following:

  • myasthenia gravis;
  • age up to 12 years;
  • allergy to components:
  • liver diseases;
  • epilepsy;
  • traumatic brain injuries;
  • acute diseases digestive tract;
  • alcoholism;
  • brain diseases.

If you do not follow the instructions, taking Novo-Passit may cause problems with concentration, drowsiness, nausea, and cramps. Tablets are taken 1 pc. three times daily with an interval of 4–6 hours. It is allowed to double the dosage if the patient has serious condition. During development side symptoms drink ½ tablet at a time. The syrup is taken three times a day, 5–10 ml. If the patient does not tolerate the antidepressant well, then the single dose is reduced to 2.5 mg.

Persen

Another popular drug based on natural ingredients, which can be bought without a prescription from a doctor. Especially for patients with interrupted sleep, insomnia, and early awakenings, there is a separate form of the drug - Persen night. The standard version of the drug has a mild effect. The antidepressant is available in tablet form and contains lemon balm extract, peppermint, valerian. The medicine provides a pronounced antispasmodic, sedative effect, and fights increased excitability. The cost of tablets is 195–250 rubles.

Persen is effective for different types disorders of the nervous system. Indications for the use of tablets are as follows:

  • neuroses for which potent therapy is not necessary;
  • vegetative-vascular dystonia;
  • insomnia;
  • prevention of psychosomatic manifestations in people exposed to stress.

While taking pills, patients may develop constipation, allergic reactions, bronchospasm, peripheral edema. Before you start using Persen, you should familiarize yourself with the contraindications. These include the following:

  • fructose or lactose intolerance;
  • cholangitis;
  • glucose-galactose malabsorption;
  • cholelithiasis;
  • age up to 12 years;
  • arterial hypotension;
  • lactation period;
  • pregnancy;
  • gastroesophageal reflux disease.

Persen involves the use of the drug orally, regardless of food intake. The tablets must be washed down with water. Adults and adolescents over 12 years of age are recommended to use them 2-3 times a day, 1 pc. For insomnia, take 2-3 tablets 30-60 minutes before bedtime. You can't drink more than 12 pieces. per day to avoid drug overdose. The course of therapy should not exceed 1.5 months. In case of an overdose, the patient may develop weakness, lethargy, tremors of the limbs, nausea, and dizziness. Intoxication with Persen has not previously been recorded.

Neuroplant

This natural remedy With minimum quantity contraindications helps improve mood and increase performance. Neuroplant is available without a doctor's prescription. The drug contains ascorbic acid, St. John's wort extract. Taking Neuroplant helps improve the patient’s psycho-emotional state and mood and provides an antidepressant effect. It is recommended to take pills for depression, pain of unknown origin, anxiety, psycho autonomic disorders Oh. Price – from 340 rubles.

Before you start taking Neuroplant, it is important to familiarize yourself with the contraindications. These include the following:

  • taking HIV protease inhibitors (Ciclosporin or Indinavir);
  • increased photosensitivity;
  • age under 12 years.

Tablets are taken 1 pc. 2–3 times a day, depending on the patient’s condition. The course of therapy is not limited in time due to the comparative safety of the drug. While taking Neuroplant, the following side symptoms are possible:

When considering cheap antidepressants without prescriptions, it is worth noting this remedy. Leuzea extract has a general tonic, adaptogenic, stimulating, strengthening effect on the body, improves mood, and increases performance. The medicine is available in the form of tincture and dragee. An antidepressant is produced using dry extract of rhizomes safflower leuzea. The cost of the drug is from 90 rubles.

Before you start taking tinctures or tablets, you should familiarize yourself with the indications. Leuzea extract is effective for the following conditions:

  • asthenia;
  • overwork (intellectual or physical);
  • decreased performance;
  • premenstrual syndrome;
  • vegetative-vascular disorders;
  • period of convalescence (recovery of the body after serious illness).

Although the drug has a natural composition and is sold from pharmacies without a prescription from a doctor, it has a stimulating effect on the nervous system and has a large number of contraindications. These include the following:

  • pregnancy;
  • lactation period;
  • chronic pathologies liver or kidneys;
  • arterial hypertension;
  • sleep problems;
  • arrhythmia;
  • spicy infectious diseases;
  • increased nervousness;
  • epilepsy;
  • alcoholism;
  • hypersensitivity to components;
  • age under 12 years.

It is important to note that the maral root contained in this antidepressant often provokes the development of side symptoms. The following side effects may occur while taking Leuzea Extract:

  • increased blood pressure (blood pressure);
  • dyspeptic disorders;
  • insomnia;
  • headache;
  • increased irritability.

Instructions for using the medicine depend on the chosen form:

  • Liquid extract in alcohol is taken 20-30 drops 2-3 times every day. You can dilute the medicine with water. The course of therapy is no more than 1–1.5 months.
  • Tablets or dragees are taken with food, 2-3 pieces up to 2 times daily. The course of treatment is no longer than 1 month.
  • Homemade tincture drink 100 ml before meals in the morning and at lunch. To prepare it, brew 1 gram of dry roots with 1 cup of boiling water, boil in a water bath for 15 minutes, and cool. The course of therapy is 2–3 weeks.

Synthetic antidepressants without a prescription

In addition to natural drugs, you can buy synthetic tranquilizers at the pharmacy without a prescription from a doctor. They also have a gentle effect on the patient’s body, but contain active chemical substances. Light tranquilizers can be used to correct minor nervous disorders. Before starting to use antidepressants, you should study the instructions for use, contraindications and composition of the drug.

Glycine

Among inexpensive and effective over-the-counter antidepressants, these tablets are the most famous. Glycine is especially popular among students and schoolchildren during exam periods. Packaging price: 17–40 rubles. The product is produced on the basis nonessential amino acid, which activates metabolic processes in the body. Glycine helps cope with aggressiveness, increased nervousness, and psycho-emotional stress. The drug activates brain activity, reduces the severity of autonomic disorders.

The antidepressant has virtually no contraindications, except for hypersensitivity to the components. During pregnancy and lactation, women can take Glycine only after consulting a doctor. Among the side symptoms, only allergic reactions are indicated in the annotation. The dosage and method of using the tablets are selected individually. For sleep disturbances, take 1 tablet at night. To improve performance, with lesions of the central nervous system (central nervous system) and psycho-emotional stress drink 1 piece. 2–3 times daily. The course of therapy is 2–4 weeks.

Afobazole

This antidepressant is characterized by low toxicity and mild action. Afobozol is available from pharmacies without a prescription. It is a selective non-benzodiazepine tranquilizer (anxiolytic). The antidepressant does not affect benzodiazepine receptors, but acts on sigma-1 receptors in the brain. Taking the drug helps improve memory, control emotions, fine motor skills, and sensory perception. The drug demonstrates effectiveness in a wide variety of pathological conditions. Afobazol is available in tablets. Package price: 375–450 rubles.

Before you start taking an antidepressant, you should familiarize yourself with the indications. Afobazole is effective for the following violations:

  • anxiety states;
  • asthenic neuroses;
  • premenstrual syndrome in women;
  • VSD (vegetative-vascular dystonia);
  • NCD (neurocircular dystonia);
  • sleep disorders;
  • withdrawal syndrome in the treatment of tobacco addiction;
  • neurasthenia;
  • alcohol withdrawal(alcohol withdrawal syndrome).

The product is relatively safe and is available from pharmacies without a prescription, but has many contraindications. These include:

  • allergy to components;
  • age under 18 years;
  • galactosemia (galactose intolerance);
  • pregnancy;
  • period breastfeeding;
  • intolerance to monosaccharides;
  • lactase deficiency.

While taking an antidepressant, patients may develop side symptoms. Afobazole often provokes the following conditions:

  • itching of the skin;
  • hives;
  • sore throat;
  • rhinitis;
  • headache;
  • sneezing;
  • nausea;
  • vomiting;
  • dermatitis.

According to the instructions, the antidepressant is taken after meals. A single dose of the drug is 10 mg, a daily dose is 30 mg. Drink Afobazol 1 tablet up to 3 times daily. The course of therapy is 2–4 weeks. The effect of the antidepressant is observed after 20 days of use. Individually daily dosage and the duration of taking the tablets may increase. Treatment with Afobazole is recommended to be coordinated with a specialist.

Tenoten

This drug belongs to the group of nootropics. Tenoten is a homeopathic remedy in the form of lozenges with a pronounced antidepressant effect. The drug contains affinity-purified antibodies to the brain-specific protein S-100. Tenoten has anti-anxiety, neuroprotective, sedative and antihypoxic effects. The tablets help cope with psycho-emotional overloads and support the body in case of disorders cerebral circulation and intoxication.

Indications for the use of an antidepressant are nervous disorders, increased irritability, autonomic disorders. Tenoten is available from pharmacies without a prescription and has virtually no contraindications or side effects. This remedy can be used to treat nervous disorders in children, nursing mothers and pregnant women. The cost of the drug is from 200 rubles per package.

The drug is taken orally, regardless of the period of food intake. The Tenoten treatment regimen for depression is as follows:

  • 1–2 pills at a time;
  • no more than 4 doses per day;
  • The course of therapy is calculated individually from 1 to 3 months.

Fenotropil

Another good over-the-counter antidepressant is this drug, which belongs to the group of nootropics. Phenotropil helps improve mood, increase the body's resistance, regulate the processes of inhibition and excitation in the cerebral cortex, activate mental activity, and increase tissue resistance to hypoxia. Phenotropil has no contraindications (except for hypersensitivity to the components). The cost of this product starts from 500 rubles per package.

The medicine should be taken for disorders of the nervous system. Indications are depressive disorders, which are accompanied by the following symptoms:

  • apathy;
  • sleep problems;
  • lethargy;
  • violation of metabolic processes;
  • problems with cerebral circulation.

Phenotropil is taken orally with a large volume. clean water. It is recommended to take the medicine in the morning. Maximum daily dose antidepressant – 750 mg. An adult patient can take 100–300 mg at one time. A course of treatment depressive states– up to three months. In some cases, you can extend the time of use of capsules by 30 days. In order to improve performance, Phenotropil is taken 100–200 ml in the morning. The course of therapy in this case is 15 days.

Neurofulol

Another remedy for depression, which can be bought without a prescription from a doctor, is widely used for neurotic and mental disorders. Neurofulol contains the following substances:

  • amino acids (methionine and tryptophan);
  • magnesium;
  • B vitamins.

An antidepressant helps support the functioning of the nervous system. Indications for use of the medicine are as follows:

  • chronic fatigue;
  • panic attacks;
  • phobias;
  • neurotic disorders;
  • depressive states;
  • digestive disorders caused by stress;
  • anxiety states;
  • sleep problems.

Taking Neurofulol helps to increase performance, improve the mental endurance of the body, the general well-being of the patient and normalize the activity of the central nervous system. The drug has almost no contraindications, except for hypersensitivity to the components. No side symptoms are observed during therapy with this antidepressant, so it is sold without a prescription. The price of the drug starts from 800 rubles per package.

It is recommended to drink Neurofulol 1 pill 3 times a day after meals. The interval between doses of the medicine should not exceed 8 hours. The course of therapy is 3 weeks. Depending on the specific case, the dosage and duration of treatment can be adjusted by a specialist. If there is no effect or side symptoms develop, you should consult a doctor for advice.

Video

Our modern life sometimes presents a lot unpleasant surprises. Stress, worry, and anxiety have become constant companions of humans. When the next turmoil unsettles the calm, everyone begins to think about the reception sedatives and stimulants. What to choose? What medicine for depression can you buy at a pharmacy without a prescription? Are such medicines dangerous?

The fight against depression is a common part of modern life.

Many people mistakenly believe that these two groups of medications act the same during stress. But it's not that simple. Going to the pharmacy for suitable drug, arm yourself with some knowledge of pharmacology.

Tranquilizers

Translated from Latin, the word “tranquilizer” means “calm.” These are psychotropic medications that are used to treat many diseases. These drugs were first synthesized in the middle of the last century. And the term “tranquilizers” came into medical use in 1956. These drugs are often called “anxiolytics.”

Tranquilizers are medications that relieve symptoms of fear and anxiety in a person. They stabilize the emotional background without negatively affecting the ability to think and memory.

The main effect of these drugs is anxiolytic (anti-anxiety). Thanks to this, the patient’s feelings of anxiety, fear are relieved, anxiety and emotional tension are reduced.


Interactions between drugs and tranquilizers

Medicines also have additional therapeutic effects:

  • sleeping pills (fighting insomnia);
  • sedative (reduce anxiety);
  • anticonvulsant (relief of spasms);
  • muscle relaxant (muscle relaxation).

Tranquilizers successfully help combat increased suspiciousness, obsessive thoughts, stabilize the state of the autonomic system, normalize blood circulation and lower blood pressure. But medications at this level are not able to help a person get rid of hallucinations, delusional states and affective disorders. Other drugs combat this – neuroleptics.

Types of anxiolytics

The list of tranquilizers is regularly updated, so there is no clear classification of such drugs. The most common tranquilizer drugs, the list of which belongs to the class of benzodiazepanes. They are divided into the following types:

  1. With a pronounced anxiolytic effect. Lorazepam and Phenozepam are considered the strongest.
  2. With moderate effect. These tranquilizers include: Clobazam, Oxazepam, Bromazepam and Gidazepam.
  3. With a pronounced hypnotic effect. These include Estazolam, Triazolam, Nitrazepam, Midazolam and Flunitrazepam.
  4. With anticonvulsant effect. The most common drugs that work to relieve convulsions are Clonazepam and Diazepam.

Neuroleptics. Antipsychotic drugs or antipsychotics. These medications are classified as psychotropic tranquilizers. They are used to treat various mental, neurotic and psychological diseases.

Modern doctors are ambivalent about prescribing such drugs - antipsychotics provoke frequent development dangerous side effects.

When prescribing antipsychotic medications, it is recommended to use new generation atypical antipsychotics. They are considered the most gentle and safe for health.


What are neuroleptics

The list of antipsychotic drugs without prescriptions is not as long as that of antidepressants and tranquilizers. The following antipsychotics can be freely purchased in pharmacies: Olanzapine, Chlorprothixene, Trifftazine, Thioridazine, Seroquel.

Do I need a prescription for tranquilizers?

Benzodiazepane tranquilizers are drugs that can be purchased in pharmacies strictly according to a prescription. These drugs cause dependence (reduced effectiveness) and addiction (mental and physical). New generations of anxiolytics can be purchased without a prescription. This:

Daytime tranquilizers. In my own way medicinal composition Daytime anxiolytics are similar to benzodiazepanes, but have a more gentle effect. In daytime tranquilizers, the anti-anxiety effect predominates, and the hypnotic, sedative and muscle relaxant effect is minimally expressed. A person taking such medications does not change the usual rhythm of life.


Features of tranquilizers

New generation anxiolytics. The obvious advantages of such drugs include the absence of addiction syndrome (as with benzodiazepane drugs). But their expected effect is much weaker, and side effects (problems with the gastrointestinal tract) are often noted.

List of tranquilizers without prescriptions

Titles Indications
Phenazepam Conditions accompanied by irritability, fear and tension
Atarax Anxiety, psychomotor agitation, increased irritability
Zoloft Depression of various types, panic disorders, obsessive-compulsive disorder, post-traumatic conditions, social phobias
Paxil Depressive states of any direction and development, stressful and post-traumatic conditions accompanied by nervousness and anxiety, phobias
Etifoxine Elimination of fear and anxiety, internal stress, persistent depression of mood due to somatic diseases, mild depression
Tofisopam Neuroses, neurosis-like states, decreased activity, apathy, stress, emotional trauma, PMS, moderate psychopathic manifestations
Rudotel Psychovegetative and psychosomatic disorders, manifestations of fear, anxiety, insomnia, irritability, neurotic conditions
Selnak Anxiety-asthenic disorders, neurasthenia, complex adaptation, generalized anxiety states
Afobazole Irritability during the fight against smoking, neurasthenia, adaptation period, alcohol withdrawal, chronic somatic diseases
Tenoten Neuroses and neurosis-like disorders, psychosomatic diseases, stress disorders, moderate central nervous system damage, irritability
Deprim Emotional and psychovegetative disorders, climacteric syndrome, PMS, depression, low mood, fears, anxiety, depressive symptoms

Antidepressants

Antidepressants are medications designed to combat the symptoms of depression. Depression– a mental disorder accompanied by a drop in mood, a decrease in intellectual abilities and motor skills.

A person in a depressed state cannot adequately assess his personality and often suffers from somatovegetative disorders (loss of appetite, muscle weakness, chronic fatigue, insomnia, lethargy, absent-mindedness, etc.).

Antidepressants not only stop such manifestations. Some of these medications even help fight smoking and bedwetting. They work as painkillers for pain of a chronic (protracted) nature.


Conditions for prescribing antidepressants

New generation antidepressants are considered the most effective. They relieve depressive symptoms subtly, delicately, without causing side effects or addiction.

Types of antidepressants

All drugs in this group are divided into two large categories:

Thymiretics. Stimulating agents. They are used in the fight against depression, which is accompanied by a depressed state of personality and pronounced depression.

Thymoleptics. Drugs with pronounced sedative properties. Such antidepressants minimize anxiety, have a relaxing effect, restore healthy sleep and relieve psycho-emotional states. Thymoleptics do not affect the state of the central nervous system in any way (they do not have a depressing effect on it).

Thymoleptic antidepressants are effective in the treatment of depressive conditions that occur with manifestations of agitation and irritability.


Features of taking antidepressants (compatibility with food)

Antidepressants are also divided into types that differ in the mechanism of action:

  1. Stopping neuronal uptake of monoamines. These include non-selective agents (blocking the uptake of norepinephrine and serotonin). These are tricyclic antidepressants: Maprotelin, Fluvoxamine, Reboxetine, Amizol, Melipramine.
  2. Monoamine oxidase inhibitors ( MAO-B inhibitor and MAO-A). These are: Transamine, Autorix, Nialamid, Moclobemide, Pirlindol.

Antidepressants are also divided into:

  • medications with a sedative-stimulating effect (Pyrazidol, Imipramine);
  • drugs with obvious psychostimulating effects (Moclobemide, Transamine, Fluoxetine, Nialamid);
  • drugs that have a sedative effect (Trazadone, Amitriptyline, Tianeptine, Pipofezin, Mirtazaline, Paroxetine, Maprotiline).

The most widespread are antidepressants with a blocking effect on the uptake of monoamines. These medications are the most effective healing effect observed after 2-3 weeks of use.

Do I need a prescription?

A prescription for purchasing antidepressant medications from pharmacies will only become necessary in the following cases:

  1. Exacerbation of the disease.
  2. Treatment of severe and long-term depression.
  3. If an atypical course of the disorder is observed.

Treatment of mild forms of depression can be carried out with the help of medications sold freely in pharmacies (over-the-counter). Antidepressants without prescriptions, the names of which are presented below, are new generation drugs.


New generation antidepressants “saw the light” in 2000

Modern drugs have an undeniable advantage over previously produced antidepressants. They give much fewer side effects, are not addictive, and have a quick healing effect on the body. The new generation of drugs can be combined with simultaneous administration other medicines.

List of antidepressants without prescriptions

Titles Indications
Maprotiline Menopausal, neurotic, psychogenic, endogenous and involutional depression, exhaustion, neurotic states, psychomotor retardation
Prozac Bulimia/anorexia nervosa, obsessions, thoughts, obsessive-compulsive disorder, psychogenic depressive states, emotional overload, PMS
Paxil Depressive states of all types (the drug is approved for use in children over 7 years old), suicidal thoughts
Deprim Chronic fatigue, emotional overload, nervous exhaustion, decreased ability to work, apathy, lethargy, irritability
Azafen Asthenodepressive manifestations, depression accompanied by anxiety and irritability, alcohol withdrawal, PMS, depression in somatic diseases
Amitriptyline Manic-depressive psychosis, bulimia/anorexia nervosa, enuresis, anxiety, insomnia
Mirtazapine Loss of interest in life, depression, accompanied by increased anxiety, apathy, lethargy, sleep problems
Herbal preparations
Leuzea extract Anxiety, low mood, apathetic neurosis-like states, decreased general tone, lethargy, chronic fatigue, impaired concentration, low mood
Ginseng tincture Severe nervous exhaustion, loss of tone, increased fatigue, low performance, hypotension, fatigue
Schisandra tincture Neurasthenic conditions, loss of tone, decreased ability to work, depressive symptoms, hypotension
Persen High nervous excitability, depressive symptoms, insomnia, irritability, anxiety, suspiciousness
Novo-Passit Neurasthenic manifestations, increased anxiety, insomnia, chronic fatigue, lethargy, decreased ability to work

At least you can buy anti-depression pills without a prescription at any pharmacy. Despite all the safety of antidepressants and tranquilizers, do not get carried away with self-medication! IN mandatory prior consultation with a doctor is required. It is absolutely forbidden to take such medications for a long time! Do not forget about the long lists of contraindications for such products. Take care of your body.

The question of what antidepressants are may be relevant even for healthy people. Most often, these medications are prescribed for depression and subdepression. Subdepression is a depressed state Bad mood, which lasts from several hours to several weeks. Subdepression is not clinical disorder, but nevertheless causes discomfort and may well be corrected with medication.

Depression can go away on its own without outside help, especially if it appears as a reaction to some painful event in life. But often depression, hopelessness, sadness, weakness and powerlessness are difficult to experience, and it is quite normal to seek help in this case.

A competent psychologist or psychotherapist can help by finding the cause of depression and working through its source. At the same time, it makes sense to take antidepressants that will help you stay afloat and cope productively with psychological difficulties.

The term depression comes from the Latin word “deprimo,” which means “to suppress.”

One of the most significant reasons for the formation of depression is stress or a traumatic event, or prolonged exposure to a psychologically difficult situation. This condition can affect any person, regardless of gender and age.

Christopher McKenney

And the symptoms can be both emotional and physical:

  • irritability and tension;
  • melancholy and despondency;
  • guilt and lack of interests;
  • slow thinking and difficulty concentrating;
  • restlessness and anxiety;
  • fear.

The physiological signs include the following:

  • sleep disturbance;
  • lack of appetite;
  • changes in taste and olfactory sensations;
  • sexual disorders;
  • violation of peristalsis;
  • pain in the chest and head;
  • increased heart rate and increased sweating.

If a person exhibits several signs, we can talk about the development of depression.

Important! Such symptoms are characteristic of other diseases. It is strictly not recommended to make a diagnosis on your own and uncontrollably take any antidepressants or tranquilizers.

There are at least 15 types of depressive disorders and three stages of their development. Diagnosis is a complex process using questionnaires and multi-level diagnostic criteria. Based on the results of this analysis, the psychiatrist decides whether to prescribe drug treatment, and if so, which drugs to use.

What are antidepressants

Subdepression or bad mood can be corrected physical activity, psychological training or even a change of environment. But the severe degree of the disease can only be treated in integrated approach, including modern antidepressants.

Pharmacological agents are intended to reduce symptoms and curb suicidal tendencies. They affect the nervous system at the chemical level.

The human brain consists of neurons - structural cells, which are excited by an electrical impulse, processing and collecting information using signals throughout life.

Data transmission is carried out by neurotransmitters - special substances, each of which transmits only certain electrochemical impulses from neuron to neuron or to other tissues. Scientists do not know exactly the entire list of neurotransmitters, but this moment Reliable medicine knows 30 types of such substances.

At least three of them are related to depression: serotonin, norepinephrine and dopamine. A decrease in their concentration leads to a depressed state. The mechanism of action of antidepressants is aimed at regulating the volume of mediators and restoring impaired chemical composition intercellular substance.

Mauro Perucchetti

Until the 50s of the last century, potent opiates and amphetamines were used as such drugs. But their composition had serious side effects, which led scientists to question and ostracize the drugs. Later it was noticed that the anti-tuberculosis drugs Isoniazid and Iproniazid also affect the mood of patients.

Interesting! The French scientist J. Deley in 1952 proved the positive effectiveness of Isoniazid not only in the treatment of tuberculosis, but also for getting rid of depression.

And by the 60s, a new generation of stimulating antidepressants had already appeared, which were characterized by reduced adverse reactions and enhanced basic properties.

How do antidepressants work?

One of the main sources of development of a depressed state is considered to be a lack of monoamines for reactions in synapses. Deficiency of serotonin and dopamine has a particularly negative effect. According to the mechanism of action, antidepressants are able to block the breakdown of these elements or prevent reverse neuronal uptake.

The most important enzyme that carries out metabolic processes through oxidation - it is a dependent amine oxidase. It metabolizes endogenous and exogenous neurotransmitters and hormones, thus maintaining their constant concentration and preventing the entry of toxic elements into the body.

Substances involved in the oxidative process are called substrates. They come in the following types:

  • dopamine;
  • serotonin;
  • norepinephrine;
  • adrenalin;
  • histamine;
  • phenylethylamine;
  • tryptamine

Antidepressants increase the concentration of neurotransmitters in synapses, thereby regulating their balance and enhancing their actions. Research has shown that these drugs have other effects. In particular, they reduce the activity of the hypothalamus, pituitary gland and adrenal glands, which manifests itself under stress.

Mauro Perucchetti

Some medications act as antagonists of inotropic glutamate receptors, which reduces the toxic effects of the aliphatic carboxylic amino acid.

For reference! There is information about the effect of drugs on receptors that regulate pain, which indicates analgesic properties.

In addition, they reduce the concentration of tachykinin neuropeptides, which are responsible for the secretion and motility of the digestive system. But the main function of drugs is to fight depression.

Who should not take antidepressants

TO general contraindications For all groups the following conditions and diseases are included:

  • increased excitability;
  • convulsions and seizures;
  • fainting and confusion;
  • decompensated kidney and liver damage;
  • hypotension;
  • circulatory and coagulation disorders;
  • thyrotoxicosis;
  • age up to 12 years.

During pregnancy, many medications should be avoided, but there are blood pressure medications that are safe for pregnant and lactating women. In addition, it is not recommended to take tricyclics and MAOIs in the following cases:

  • heart pathologies;
  • arterial hypertension 3 degrees;
  • glaucoma;
  • ulcers in the stomach;
  • urethral atony;
  • lactation period;
  • prostatic hypertrophy.

Additional contraindications to taking SSRIs are psychotic-type depression (especially with pronounced suicidal tendencies), alcohol and chemical poisoning.

Classification

In psychiatric practice, it is customary to divide drugs into several groups. Here is the most convenient classification of antidepressants to use.

Monoamine oxidase inhibitors

Such agents can be non-selective and selective. Non-selective drugs constitute the first generation group. Their properties include suspending the activity of deamination enzymes that remove amino groups from molecules in serotonin, norepinephrine and dopamine. The category includes the following medications:

  1. Iprazide is a drug with atropine-like, hypotensive, sympatholytic effects. Used in psychiatry for the treatment of moderate and mild depression, with circular psychosis. It is also able to reduce pain in vascular pathologies and have a positive effect in atherosclerosis and angina. Available in the form of tablets or dragees. The dosage is 0.025-0.05 g 304 times a day. As the condition improves, the dose is gradually reduced to 0.01-0.025. The course of treatment is 2 months.
  2. Nialamide is a derivative of isonicotinic acid, an inhibitor of monoamine oxidase, eliminating lethargy, lethargy, and anxiety in depression. The therapeutic effect appears 1-2 weeks after the start of treatment. The duration of the course is long - from 1 month to six months. Helps with various pain syndromes associated with damage to nerve endings. Dosage – 50-75 mg per day, divided into 2 doses. In an amount of 50-200 mg per day, it is effective in the treatment of alcoholism.
  3. Tranylcypromine is a drug from the group of antidepressants with a non-selective effect on MAO. Increases the concentration of neurotransmitters, but can provoke the development of a hypertensive crisis, so patients with arterial hypertension it should be prescribed with caution. Dosage – 5-10 mg/day initially, every 2-3 days the amount is increased by 5-10 mg to a maximum of 40-60 mg per 24 hours. Upon reaching therapeutic effect the dose is reduced in the same order.

Drugs of this classification of psychotropic drugs are not combined with anti-cold, analgesic and anti-hypoglycemic compounds, which is associated with inactivation of hepatic fermentation.

Important! While taking it, you must follow a special diet - with the exception of foods containing tyramine and tyrazine (cheeses, smoked meats). This is required to prevent the risk of developing myocardial infarction and hypertensive crises.

Non-selective inhibitors are highly toxic and cause side effects from the digestive, nervous and vascular systems. May have a negative (suppressive) effect on sexual and reproductive functions, form manic episodes in patients with a certain predisposition.

The second group of MAO inhibitors is selective, much better tolerated, and does not require a special diet. Side effects of antidepressants are reduced, as is the risk of drug interactions. But their activity is somewhat weaker. The category includes the following drugs:

  1. Moclobemide, which is prescribed for depressed conditions of various etiologies. The average daily dosage ranges from 300 to 600 mg.
  2. Bethol – strong remedy reverse action, increasing the concentration of monoamines. Suitable for the treatment of reactive and neurotic conditions, manic and depressive syndrome, schizophrenia, alcoholism. The composition is available in several forms and can be used either orally (30-150 mg/day), parenterally (up to 400 mg/day) or as infusions. To avoid causing insomnia, it is used during the daytime.
  3. Selegeline is similar in structure to ephedrine, but differs in its mechanism of action. It is prescribed to increase the volume of monoamines and for parkinsonian syndromes. The peculiarity of the drug is that it can enhance the effect of levopoda, which is not typical for other drugs in the group.

Despite the fact that side effects are reduced, allergic reactions and digestive disorders may occur. In some cases, patients complained of tachycardia and trembling of the fingers after taking it.

Important! IN Lately Pharmacology offers drugs with a milder effect on the body. But psychiatrists do not completely abandon the use of MAOIs.

SSRIs

This group of drugs is called selective serotonin reuptake inhibitors or SSRIs; they began to be used only in the second half of the last century and quickly gained some popularity.

The main feature is that they are able to delay the reuptake of monoamine, ensuring its optimal concentration. The drugs are easily tolerated, provide reduced anticholinergic side effects, relieve anxiety, nervous disorders, phobias and panic of various etiologies.

During the studies, secondary pharmacological properties of medications were also noted. In particular, they inhibit the retake of norepinephrine and dopamine, to a no less significant extent, and each representative of the group has individual properties. The list includes the following drugs:

  1. Fluoxetine improves mood, relieves feelings of hopelessness and fear, feelings of frustration and suffering. At the same time, it does not have a negative effect on the heart and has a fairly high bioavailability - about 60%. It combines a rapid antidepressant effect with a stimulating one. The dosage is 20 mg/day at a time, if necessary, the amount is increased, but not more than 80 mg/day.
  2. Paroxetine is an anti-anxiety drug that exhibits agonism at norepinephrine receptors. When taken, the duration and quality of sleep quickly improves, and the manifestations of phobic disorders and depressive disorders decrease. The medication is considered the safest of the entire group. The optimal therapeutic dose is 20 mg per 24 hours, preferably taking tablets in the morning.
  3. Citalopram is a composition that does not provide a sedative reduction in irritability and anxiety and has a slight ability to bind to histamine, adrenergic and cholinergic receptors. It carries out the process of capturing serotonin directly in the brain. The medicine does not affect the liver and kidneys, and does not cause weight gain. The average daily dosage is 20-60 mg per 24 hours. At serious violations in the work of the heart, the amount is halved.

Even the most reduced adverse reactions can cause dyspeptic disorders and allergic manifestations when taking SSRIs. In the last trimester of pregnancy, a violation of the embryonic development of the fetus may be detected. Cases of sexual and reproductive dysfunction have been observed.

Important! The occurrence of side effects varies for each patient. It depends on the general condition, accompanying pathologies, severity of the underlying disease.

Mauro Perucchetti

Antidepressants with tertiary formula

The mechanism of action of this group of medications is similar to the activity of selective serotonin inhibitors. The difference is that they also interfere with the retake of norepinephrine, thereby increasing the concentration of the transmitter. Previously, these medications were prescribed for particularly severe disorders: suicidal and psychotic manifestations. But with the advent of representatives of the new generation, this need has disappeared.

A group of tricyclic antidepressants is intended for the treatment of depression of various etiologies and helps with sleep disorders. In addition, drugs in this category are characterized by analgesic activity, which implies a strong analgesic effect.

As a rule, tricyclic antidepressants are inexpensive and are widely available in pharmacies. The disadvantages include the following factors:

  • teratogenicity;
  • severe consequences of overdose;
  • a large number of adverse reactions;
  • presence of cross-resistance.
  • an extensive list of contraindications.

The products got their name thanks to a chemical formula that includes three cycles of activity.

Their action is based on participation in biological processes and metabolism of substances responsible for inhibition and excitation reactions in the brain.

Within the group, it is customary to distinguish two subclasses:

  1. Tertiary amines are tricyclics. They have more pronounced stimulating activity and less anti-anxiety properties. They carry out a retake of only one neurotransmitter.
  2. Secondary amines tricyclics. They have increased sedation, but also give more side effects and provide the capture of both serotonin and norepinephrine. There is also an atypical subclass that has a similar formula, but the antidepressant effect for them is not the main one.

There are several main and most used drugs of the general category:

  1. Amitriptyline, which has pronounced anticholinergic and antihistamine properties. At certain dosages it is also capable of stimulating and providing a psychic-energizing effect. It eliminates anxiety, internal tension, and feelings of fear. Used to treat phobias, childhood enuresis, anorexia and neuroses. It is often used to prevent migraines. Start taking 50-75 mg per day, gradually increasing the dose to 300 mg per day. Cancellation should also be done in stages.
  2. Imipramine, which is considered one of the first tricyclic antidepressants. In connection with his high efficiency has been used for a long time, despite the invention of new generation products. Its therapeutic value is especially high in the treatment of recurrent depression. The composition helps improve mood and reduce inhibition. Initial dosages are 75-100 mg, with the addition of 25 mg daily, the amount is increased to 250 mg per day. The course of treatment is 6 weeks, after which the dose is reduced.

According to statistics, 7 out of 10 patients were able to return to stable calm state after taking tricyclics. But the remaining 3 did not feel any improvement, which may be due to a long course of therapy. Many people are not suitable for long-term treatment due to poor tolerance to medications.

Important! These drugs are not tranquilizers, so the idea that they can be addictive should be considered erroneous.

When using medications in this group, it is important to observe the dosage and frequency of administration. In some cases, interruption of therapy is fraught with withdrawal syndrome, which is expressed in adverse reactions:

  • violation of peristalsis: constipation;
  • blurred vision;
  • tachycardia;
  • difficulty swallowing;
  • narrowing of the esophagus;
  • confusion;
  • cardiotoxic effect;
  • allergy.

Emergence negative reactions limits the use of formulations, especially in outpatient practice. However, tricyclics are currently effective for treating depression.

All types of antidepressants are divided according to the principle of action or the type of neurotransmitters they affect. For each person, you can choose the most optimal option that matches your condition. But only a psychiatrist can prescribe. All drugs have their pros and cons, a list of contraindications and side effects, but they are united by one rule - you cannot suddenly refuse therapeutic regimen and it is strictly forbidden to self-medicate.

Ask an expert a question in the comments

Depression is not uncommon for modern people. But with such a diagnosis, few people rush to see a psychotherapist, preferring to take antidepressants sold without a prescription.

Can depression be treated with over-the-counter antidepressants, and how to choose the best one? effective drug?

When do you need antidepressants without a prescription?

Before choosing an antidepressant, you need to make sure whether you really need to fight your condition by medication or it is enough to eliminate the factors that cause depression. Before using antidepressants, experts recommend minimizing stress, reviewing your lifestyle, and normalizing your rest and work schedule.

It should immediately be noted that for people with severe depressive disorders, antidepressants sold in pharmacies without a prescription are not suitable. Anti-depression medications have a lot of side effects, and their use and dosage should be selected by a doctor on a strictly individual basis.

Antidepressants have different composition and the chemical structure and methods of their effect on the body are very different. After all, depression is different - and the same drug in the same dosage can lead to recovery in some patients, while in others, on the contrary, it can lead to a worsening of the condition. Therefore, using antidepressants without a prescription is very imprudent if the depressive state is already in the nature of a mental illness and not a temporary nervous disorder.

Note! Usually available without a doctor's prescription sedatives, amino acids, metabolic drugs, “weak” tranquilizers and nootropics. It is impossible to buy strong antidepressants at a pharmacy without a prescription.

If a person just needs to reduce the nervous system’s reaction to nervous stimuli and improve their mood, then “mild” antidepressants will undoubtedly help improve the quality of life. In addition, such drugs help with the following conditions:

  • For pain that is of an uncertain nature;
  • For appetite and sleep disorders;
  • At frequent attacks groundless anxiety;
  • For chronic fatigue;
  • In the treatment of alcohol and drug addiction;
  • For attention disorders;
  • In the treatment of anorexia and bulimia.

Antidepressants without a prescription have a very limited list, but all of them do not have side effects on the body and it is almost impossible to get poisoned by them.


Herbal antidepressants

It is better to start treating mild nervous disorders with medications plant origin– such antidepressants can be easily purchased without a prescription at any pharmacy. Herbal antidepressants also help with anxiety and depression that appear during stress and anxiety. Here is the top list of the best over-the-counter herbal antidepressants.

List of Russian herbal medicines, mild antidepressants, for the treatment of depression, with the name, description of the action of the drug and the average selling price in the pharmacy:

Name Action Price (at the beginning of 2019)
Neurofulol Eliminates neurotic disorders (chronic fatigue), relieves anxiety, fights various phobias. 950 rub.
Doppelherz neurotonic It has a mild antidepressant effect, improves sleep quality, and improves mood. Used in the treatment of mild and moderate severity, to eliminate states of chronic anxiety and pronounced neurotic reactions. 350-450 rub.
Valerian tincture Removes strong nervous tension, used in severe nervous exhaustion. 30-60 rub.
Novo-passit Used to relieve stress and neurasthenia.
Relieves irritability, nervous excitability, has sedative effect. They are the most popular among managers, accountants and other office workers. 400-800 rub. (depending on packaging)
Leuzea extract Improves mood, increases performance, and has a general tonic effect. 110-140 rub.
St. John's wort extract (Deprim, Neuroplant, Negrustin, Gelarium) Improves mood, regulates sleep, treats anxiety and mild depression. 210-360 rub. (depending on the drug)

Note! Doctors say that most people who take antidepressants do not suffer from nervous system problems. Most often, people themselves give themselves a “depression mindset” and then try to recover from the contrived condition.

The following herbal remedies also help get rid of depression:

  • Infusion of immortelle and– improve sleep, relieve the feeling of overwork;
  • – increases stress resistance, is used to treat mild depressive conditions;
  • , oregano,– mild antidepressants that have virtually no side effects;
  • – has a calming effect on the nervous system.

All of these herbal preparations are used for mild to moderate degrees of depression and differ soft effect, can be used for sleep disorders, anxiety, and restlessness. An exceptional advantage of herbal antidepressants is that you can buy them cheaper than other drugs of the same effect.

Synthetic antidepressants

Synthetic drugs for the treatment of mild types of depression help relieve nervousness, reduce anxiety and restlessness, and normalize sleep. Such drugs include metabolites, nootropics, and tetracyclics.

Antidepressants synthetic origin(Russia). Top list of the best synthetic over-the-counter antidepressants:

Name Action Price (at the beginning of 2019)
Glycine Has a calming effect, relieves aggression, improves emotional state. Thanks to soft action, the drug is recommended for teenagers for use during exams, sessions, etc. 70-90 rub.
Zyban Relieves irritability, attacks of anxiety, anger, improves mood and overall well-being. Used successfully in the treatment of tobacco and alcohol addiction to suppress nervousness. 1200-4500 rub. (depending on packaging).
Ludiomil (maprotiline) Treats most types of depression, reduces irritability and anxiety. Good pills for the treatment of anorexia and stress due to exhaustion during weight loss. 1100 rub.
Amitriptyline Renders sedative effect, an analgesic effect for neurological pain, treats depression, phobias, and nocturnal enuresis in children. 110 rub.
Anafranil (clomipramine) Treats depression of various etiologies, neurotic disorders, phobias, panic attacks. 670 rub.
A nootropic drug that has a strong antidepressant effect. It has almost no contraindications or side effects. 230 rub.
Used to eliminate symptoms of depression and neurasthenia. 470 rub.

In neighboring countries there is a list of drugs for depression that have the same effect:

  • Ukraine: Mirtazapine (300-500 UAH), Venlaxor (250-480 UAH), Paroxin (200-550 UAH), Fluoxetine (40-50 UAH);
  • Belarus: (80-100 Belarusian rubles), Chaga extract (1.24-2.5 Belarusian rubles), Apilak (3-4 Belarusian rubles), (1-2.5 Belarusian rubles) .

There are a large number of synthetic antidepressant drugs, but only a few of them are available without a doctor's prescription. On some forums you can find a whole list of such drugs (for example, Prozac, Sonocaps, Metralindole, etc.), but all of these drugs are quite potent and powerful antidepressants, and you cannot buy them at a pharmacy without a prescription without breaking the law.


How to take antidepressants correctly

Antidepressants that can be purchased without a prescription have a lasting effect in eliminating nervous conditions. But this does not mean that they can be used uncontrollably long time without serious consequences.

Many drugs in this series have contraindications and side effects. The most common contraindications to taking antidepressants include:

  • Age under 18 years;
  • Pregnancy and breastfeeding;
  • Individual intolerance to the components of the drug.

But each antidepressant also has its own contraindications, which should be taken into account when choosing a medication.

People often mistakenly think of antidepressants as “vitamins” for the brain, which they take to improve their mood and overall well-being, so they can be taken without harming their health. But this is not true - taking antidepressants is limited to a certain period.

Weak antidepressants, available without a prescription, can be taken for 2-3 months, because... Treatment with such drugs is long-term, and the effect of taking it usually occurs after 6-8 weeks from the start of use. You can use drugs from the lists above.

The compatibility of antidepressants with other medications should also be taken into account. Thus, a combination of tranquilizers and antidepressants can lead to increased side effects and a slowdown in metabolism, and antidepressants in combination with sympathomimetics can cause.

Many people do not feel what they think is the desired effect after taking antidepressants without a prescription. Reviews from such patients indicate that the drugs do not help cope with depression and are ineffective. But usually the problem is that a certain medicine is not suitable for this person or is used in the wrong dosage. Therefore, to select the right drug, it is better to seek help from a doctor.