What is a sedative state? Review of sedatives: what kind of pills are there for nerves and stress? Herbal sedatives: list

To suppress internal anxiety, agitation and irritability, doctors prescribe sedatives. What is sedative action? Simply put, these are medications that calm the nervous system. They allow you to overcome neuroses and other disorders that worsen the quality of life and negatively affect your mood.

What drugs have a sedative effect?

The action of sedatives is aimed at stimulating the calm activity of the nervous system and reducing the excitation of impulses in the brain.

Such funds perform important functions for humans:

  • Promotes rapid falling asleep and deep, uninterrupted healthy sleep.
  • Reduce internal anxiety.
  • Regulate the functioning of the central nervous system.
  • Help enhance the properties of certain medications (painkillers and sleeping pills).

For the most part, sedatives do not cause side effects, addiction, and do not have a negative impact on the functioning of internal organs and systems. The advantage of such drugs is that they are well tolerated by almost everyone who takes them. It is precisely because of this positive effect that a sedative acts on a person that it is often used in therapy for the elderly and pregnant women.

Drugs with a sedative effect are prohibited from being taken by people who, during their course of taking them, continue to work with dangerous goods, machinery, or are engaged in activities related to driving a car.

Sedatives may have a minor effect on the functioning of the musculoskeletal system. Otherwise, doctors give preference to these sedative drugs, even if there are other strong drugs in modern pharmacology.

When should you take sedatives?

Tablets with a sedative effect are now available in a large selection in pharmacies. When should you resort to their help? The nervous system of a healthy person should be in a state of balance. Under the influence of negative internal or external factors, it is disrupted, and the person becomes emotionally hot-tempered, cannot control himself and even sometimes be aware of his actions.


To establish a balance for such disorders, sedatives are prescribed. They allow you to improve the quality of life of both the patient and his immediate circle. Various factors can provoke neurosis, stress or similar feelings.

These include:

  1. Problems at work or school.
  2. Passing exams or reports.
  3. Conflict in the family or at work/school.
  4. Overwork and insomnia.

In most cases, a mild sedative, which can be purchased at a pharmacy without a prescription, helps. In more complex and serious situations, the prescription of a potent medication with the desired sedative effect is done by a qualified specialist.

Classification of sedative drugs

In addition to the fact that drugs with a sedative effect are potent and mild, they are also divided according to the nature of their origin.

When classifying, the following main groups of funds are distinguished:

  1. Bromides containing potassium and sodium.
  2. Herbal medicines.
  3. Combined herbal medicines.


The active component of the first category of sedatives is bromine anion. The main form of release of such products is solutions and mixtures. This was done in order to reduce their irritating effect on the gastrointestinal tract.

The work of bromides is aimed at activating the processes of impulse inhibition in the cerebral cortex. A large dose of such a sedative can cause convulsions, and a toxic dose (causing pathological changes in the body) provokes coma. These sedatives are eliminated primarily through the kidneys within 12 days, and their effect lasts exactly the same amount of time.

Sedative preparations of plant origin are made on the basis of valerian, peony, motherwort and passionflower. They relax the body, allowing you to achieve peace of mind and tranquility. Such medications are produced in the form of tablets, capsules, alcohol tinctures, dry raw materials in disposable bags or general packaging. This does not affect the strength of their action.

Combined sedatives are those that simultaneously contain a complex of active ingredients. Their effect on the body is stronger than other anti-anxiety medications.

When and how to take bromides?

Bromides are synthetic sedatives that are prescribed at the initial stage of hypertension, for insomnia, for hysteria and neuroses.

Indications for the use of these sedatives may also be complex therapy carried out in the treatment of epilepsy.

It is necessary to use these drugs with a sedative effect according to the following scheme:

  • Inside and before meals.
  • Dosage no more than 1 gram per single dose.
  • The frequency of daily dosages is 3-4 times.

IMPORTANT! Regular cleansing of the intestines, rinsing the mouth, and water procedures will help minimize the side effects from taking bromides. To enhance the effect of the properties of the drug, you should limit your consumption of table salt.

The dosage in each case is selected individually for the patient and depends on the reasons for the prescription. After the first use of such a sedative, there will be no noticeable result. The medicine has a cumulative effect, so you can feel its effect after at least 3-4 days. The total duration of the bromine-containing course is 2-3 weeks.

Bromides with a potassium compound, which have a sedative effect, can also be produced in the form of powder and tablets. The liquid form of release with various dosages is used mainly for use in children. The drops are mixed with any fruit syrup and given to the child. To reduce the irritating effect of bromides on the intestines, the doctor may additionally prescribe reparants (substances that stimulate the regeneration of the gastric lining).

Plant-based sedatives: indications and course of treatment


Herbal medicines can be compared in their properties and effects to the simultaneous intake of caffeine and bromide.

The main indications for the use of these sedatives are:

  • Insomnia.
  • Hysteria.
  • Neurosis.
  • Arrhythmia in a mild form.
  • Cardioneurosis.

Also, preparations based on a plant that has a calming effect are actively used in the complex treatment of angina pectoris or hypertension. The prescribed dosage of sedatives depends on the age of the patient and the severity of his condition. The sedative effect becomes noticeable within a few minutes after administration.

The course of application depends on the plant on which the medicine is based:

  1. On valerian: the duration of the course does not exceed 10 days. 3-5 doses are allowed per day.
  2. On motherwort: 3-4 doses during the day, 30-50 drops at a time. You should take the medicine before meals. To brew dry raw materials, 1 tbsp is enough.
  3. On medicinal peony: the course of treatment is about 20-30 days. Single dosage: 30-40 drops 3-4 times a day.
  4. On passionflower (passion flower): taken no more than 4 times a day. When released in tablets - 1 or 2 pcs., in syrup - 5-10 ml.

If there are contraindications or personal intolerance to any herbal-based sedative, you should stop taking it.

The choice of sedatives is large enough to find an analogue that is suitable for its sedative effect. Preparations based on valerian can enhance the properties of sleeping pills, tranquilizers or neuroleptics.

List of sedatives

To relieve psychomotor agitation, the patient may be prescribed sedatives, which act much more efficiently and quickly. This mechanism of operation became possible due to the content of several plant sedates in their composition.

The list of such sedative drugs includes:

Corvalol based on valerian and mint. It also contains alcohol and phenobarbital.

Novo-passit

Persen

Valocormid based on valerian, lily of the valley, sodium bromide, menthol and belladonna.

This is an incomplete list of names of such drugs. They differ in component composition, price and strength. These sedative drugs are widely used in modern medicine.

What is glycine and how to use it?


Glycine is an amino acid that is actively involved in many processes occurring in the human body. It belongs to drugs with a sedative effect. Its advantage lies in the ease of penetration into almost all tissues and fluids of the body; it also reaches the brain without problems.

This medicine has the following effects:

  1. Improves metabolic processes of the central nervous system.
  2. Eliminates depressive moods.
  3. Relieves irritability.
  4. Helps you fall asleep quickly.
  5. Improves blood supply to the brain.

The sedative properties of this drug have been proven over the years. It is actively prescribed to suppress hyperactive actions, for neuroses, psycho-emotional stress, sleep problems and decreased mental activity. It is used in complex therapy for recovery from traumatic brain injuries, encephalopathy and ischemic stroke. These sedatives affect the tone of the sympathetic nervous system.

IMPORTANT! It is prohibited to take glycine if you are personally intolerant to the drug component.

The release form of glycine is tablets. The maximum daily dosage of a sedative is 0.3 grams. It should be divided into equal parts into 2-3 daily doses. The duration of the course is no more than 1 month. To be effective, the tablets should be dissolved under the tongue until they disappear completely.

Side effects of sedatives

Drugs that have a sedative effect on the human body can sometimes cause side effects when taken. The list of drugs of this kind is quite wide, but has not been fully studied.

Therefore, when prescribing sedatives, their use should be taken seriously. You should be in constant contact with your doctor in order to identify developing pathologies in a timely manner. In each case, their action can be completely different.

Common side effects are:

  • Decreased concentration and attention.
  • Increased lethargy and apathy.
  • Drowsiness.
  • Decreased speed of mental activity.
  • Slowing of motor reactions.
  • Constipation or stomach upset.
  • Dry mouth.
  • Headache.

In most cases, taking sedatives does not distract a person from their daily routine and allows them to fully control themselves, be aware of their actions and go to work. They take medications at night, which has virtually no effect on daytime activity.

Simultaneous use of antisedatives and sedatives is not allowed.

Who prescribes sedatives?

Having figured out what kind of sedative effect this is, you should know who to contact to prescribe such drugs. You can get a prescription for strong sedatives, which are otherwise not available in pharmacies, by contacting a psychiatrist or psychotherapist. Their specificity is working with mental illnesses, nervous disorders and disorders. These medical professionals are responsible for determining the severity of symptoms of the disease and prescribing sedative medications to treat it.

For mild disorders, you can seek help from a psychologist. In addition to psychological assistance, he can recommend medications with a mild sedative effect. This specialist does not make appointments, as he is not a medical professional. This means that his appointments are advisory in nature.

Price of sedatives


The price of sedative bromides varies from 20 rubles to 300. The cost depends on the volume of the package purchased and the strength of the drug.

In conclusion about sedative medications

Drugs that can sedate the nervous system have recently found widespread use. This is due to the rather “nervous situation” in modern society, as well as the safety and virtual absence of contraindications for sedatives. They rarely cause side effects, which means that they are well tolerated by almost all patients, including children.

The most popular prescription drugs are sedatives of plant origin, as well as glycine. Their effect is quite mild, so they are not used as an independent method of treatment for serious disorders, but are an important component of complex therapy.

Important! Self-medication using sedative medications is unacceptable. Appointments must be made by a specialist.

What do we do when we are nervous? We look for valerian or validol in the medicine cabinet. These are the most popular sedatives and are used everywhere. “Sedatives” translated from French means “calming”, and this is the main task of such drugs. They depress the central nervous system, relieve irritability and nervousness, and bring peace. Today, many new generation sedatives have appeared. Perhaps it's time to forget about valerian and try something more effective?

Sedatives - list

What does it mean – a new generation sedative? This is a combination drug that combines antihistamine, sedative and relaxation properties. Typically, such medicines are of mixed origin, where plant extracts are combined with advances in the chemical industry. Such drugs include:

  1. Nobrassite, where guaifenesin is combined with extracts of valerian, passionflower, lemon balm, hawthorn and other plants.
  2. Combination drugs include the well-known Corvalol, Validol and. The first two drugs contain a-bromoisovaleric acid ester, sodium salt of phenobarbital, peppermint oil in an alcohol solution. The latter is menthol dissolved in isovaleric acid. This is an excellent sedative, proven over the years.

Bromine-based sedatives

Sedative drugs based on bromine and bromine salts began to be used in the nineteenth century. This substance inhibits the reactions of the central nervous system, due to which the process of excitation is inhibited and nervousness goes away. Today, bromine preparations are still used; camphor bromide, sodium bromide and potassium bromide are used in combination with plant extracts and sold separately. One of the advantages of such drugs is the concomitant antihistamine effect. The downside is that bromine is poorly excreted from the body, and therefore quickly accumulates in tissues. An overdose can cause complications, so long-term use of such drugs is not recommended.

List of herbal sedatives

In folk medicine, flowers, roots and leaves of plants have long been used as a sedative. Their alkaloids and esters have a mild tonic and relaxation effect, promote deep and sound sleep without provoking it, like sleeping pills. Plants with pronounced sedative properties include:

  • valerian;
  • St. John's wort;
  • passionflower;
  • kava-kava;
  • mint;
  • Melissa;
  • hawthorn;
  • peony root.

In modern medicine, drugs based on them are actively used. We can say that the best sedative is a sedative of plant origin. As a rule, it acts mildly, is not addictive, and has few contraindications. Herbal preparations that use optimal combinations of herbs and extracts include:

  • Persen;
  • Novopassit;
  • Deprim;
  • Dormiplant;
  • Life 600;
  • Stressplant;
  • Negrustin;
  • Tsirkulin and others.

But even such seemingly harmless medications must be prescribed by a doctor. St. John's wort is contraindicated for pregnant women, valerian - epileptics, other herbs also have specific uses.

Magnesium-based sedatives

A lack of certain macro- and microelements in the body can provoke a nervous disorder. This primarily applies to magnesium deficiency. It is not surprising that often, as a sedative, doctors recommend starting to take this element along with B vitamins, which have a general strengthening effect on the body and support the activity of the nervous system. Such drugs include Magne B6 and others.

Sedatives have been used for a long time to treat diseases of the nervous system. The mechanism of their action is a regulatory effect on the brain - inhibition of excitation processes and activation of inhibition. These drugs have moderate sedative and anti-anxiety effects. This group of drugs does not have a hypnotic effect, but they facilitate the onset and promote deeper and more restful sleep. Well tolerated by patients without any serious side effects. Do not cause addiction, physical or psychological dependence. They enhance the effect of certain groups of drugs, such as painkillers, sleeping pills and others that have a calming effect on the nervous system.

Due to the beneficial effects of sedatives and the minimum of adverse reactions to them, these drugs are widely used in everyday medical practice, especially in the treatment of elderly people.

According to the classification, there are several groups of sedatives, the leading of which are herbal medicines. We'll talk about them below.

Valerian preparations

Valerian root reduces the excitability of the central nervous system and has a mild antispasmodic effect.

The roots and rhizomes of valerian contain many active substances that have medicinal properties such as reducing the excitability of the central nervous system and reducing spasm of smooth muscles (antispasmodic effect).

Indications for taking valerian preparations are insomnia, increased nervous excitability, and neurocirculatory dystonia.
Available in various dosage forms:

  • tincture with 70% alcohol - recommended doses for adults are 20-30 drops 3-4 times a day;
  • thick valerian extract in the form of tablets or capsules - 0.02–0.04 g (1–2 tablets) 3–4 times a day;
  • capsules containing a hydrophilic complex of valerian (Valevigran), take 1-2 capsules 2-3 times a day 30 minutes before meals;
  • dry raw materials in filter bags and in a common pack - used for brewing tea and preparing a decoction (2 teaspoons of crushed dry raw materials are poured into 200 ml of cold water and boiled for 5 minutes, then filtered), recommended doses - 15–30 ml (1 –2 tablespoons) 3-4 times a day.

A contraindication to taking valerian preparations is only the patient’s individual hypersensitivity to them.
It is generally well tolerated by patients. In some, extremely rare cases, drowsiness, increased fatigue, etc. are observed.

Paeonia officinalis preparations

Indications for taking peony medications are neurasthenia, sleep disorders, and neurocirculatory dystonia.
Available in tincture form in 100 ml bottles. It is recommended to take 30–40 drops of tincture 3 times a day. The course of treatment is long – 3–4 weeks.

Contraindicated in case of individual hypersensitivity.
The only side effects that should be noted are the occurrence of allergic reactions in case of hypersensitivity to this drug.

Motherwort preparations


Motherwort preparations not only soothe, but also to some extent reduce blood pressure.

The herb of this medicinal plant includes substances that, in addition to a moderate sedative, also provide.

They are used for neuroses, increased nervous excitability, neurocirculatory dystonia, as well as in the early stages of hypertension.
They are produced in the form of an infusion in bottles of 25 and 50 ml, as well as in the form of dry raw materials in a total pack weighing 50 and 100 g.

It is recommended to take the tincture 3-4 times a day, 30-50 drops before meals. An infusion is prepared from dry raw materials: 15 g of crushed herbs are poured with 150–200 ml of water at room temperature and placed in a water bath. Heat over low heat for 15 minutes, stirring occasionally. Strain and squeeze. Take 15 ml (1 tablespoon) 3-4 times a day before meals.

Motherwort preparations are contraindicated if the patient's body is hypersensitive to them.
Possible side effects are drowsiness, increased fatigue, dizziness. However, they are extremely rare.

Passionflower extract (passion flower) – Alora preparation

The components of the drug reduce the excitability of the central nervous system, producing a sedative effect. While taking the drug, patients' mood improves, manifestations of anxiety and mental stress decrease, and sleep quality improves. In addition, Alora also has an anticonvulsant effect.

Indications for taking this drug are:

  • neurasthenia and depression;
  • anxiety states;
  • psycho-emotional stress;
  • increased irritability;
  • sleep disorders;
  • post-infectious asthenia syndrome.

It is also used in the complex treatment of pathological conditions such as hypertension, cerebral vascular crises.

Available in the form of tablets and syrup.
Tablets are taken 3-4 times a day, 1-2 pieces before meals. In case of sleep disorders - 2-3 tablets 1 hour before planned sleep. The duration of treatment is determined individually and depends on the initial severity of the patient’s condition and his response to the therapy.

The syrup is taken 1-2 teaspoons (this is 5-10 ml) three times a day before meals. To improve the quality of sleep - 2 teaspoons (10 ml) an hour before bedtime.

Alora is contraindicated in case of hypersensitivity to the components of the drug, as well as during pregnancy and lactation.
When taking the drug in recommended doses, the development of any undesirable effects is unlikely. Allergic reactions are extremely rarely diagnosed.

In case of severe organic pathology of the digestive tract, the drug is used with caution. Alora has not been tested on pregnant or lactating women, so possible negative effects on the fetus and infant are unknown. The drug in syrup form is not recommended for use by patients because it contains sucrose. When treated with this drug, working with dangerous machinery and driving vehicles should be avoided. It is also not recommended to drink alcohol during the treatment period.

Combination drugs

Most sedative herbal preparations contain several active ingredients at once - due to this, their positive effects are potentiated and the expected effect is achieved faster.

Dormiplant

Contains dry extracts of valerian root and lemon balm leaves. It has a calming effect on the body as a whole, and also improves falling asleep and quality of sleep. Indications for use are a state of nervous overstrain and sleep disturbances arising from this background. Take the drug 2 tablets 30 minutes before bedtime - for the purpose of normalization. For anxiety conditions - 2 tablets 2-3 times a day. Take the tablets without chewing, with water. The duration of treatment is determined individually. Contraindications: depressive conditions, as well as hypersensitivity to the components of the drug. Side effects are rare. Nausea, headache, dizziness, drowsiness, confusion, intestinal spasms, and allergic reactions are possible. Of the special instructions, it should be noted that experimental studies of the drug have not been conducted on pregnant and lactating women, therefore there is no data regarding the safety of taking it during these periods. Since side effects include confusion and drowsiness, caution should be exercised when taking Dormiplant by persons whose work involves driving vehicles or operating heavy machinery.

Menovalen

Capsules containing lipophilic complexes of valerian (50 mg) and peppermint (25 mg). Has a mild sedative effect. Helps you fall asleep quickly. It is used for mild neuroses, manifested by nervous overexcitation, decreased concentration, feelings of anxiety and restlessness, and sleep disturbances. Take 1 capsule three times a day half an hour before meals or 1-2 capsules an hour before bedtime. Adverse reactions are extremely rare, develop with prolonged use of the drug, and are reversible. These are side effects from the central nervous system, characteristic of the entire group of sedatives, as well as a decrease in blood pressure, a feeling of palpitations and compression behind the sternum, heart rhythm disturbances, nausea, vomiting, heartburn, abdominal pain, constipation, bitterness in the mouth and pain in the right hypochondrium, allergic reactions. It is not recommended to take Menovalen during pregnancy and breastfeeding.


Novo-passit

It contains valerian extract, St. John's wort herb and guaifenesin. In addition to the hypnotic and antidepressant effects of medicinal herbs, guaifenesin also has an anti-anxiety and smooth muscle relaxing effect. Indications for taking this drug are standard - like all sedatives. Available in the form of tablets and oral solution. Recommended doses: 1 teaspoon (5 ml) or 1 tablet orally 3 times a day. If necessary, the dose can be doubled. The interval between taking the drug should not be less than 4 hours. Contraindications are hypersensitivity to the components of Novo-passit, epilepsy and myasthenia gravis. Side effects are similar to those of other sedatives. While taking Novo-passit, it is not recommended to be exposed to ultraviolet rays for a long time. Use with caution in persons with severe liver dysfunction. The safety of the drug during pregnancy and lactation is unknown. When taking the drug, absent-mindedness and a decrease in the speed of reactions are possible - patients should refrain from activities that require high concentration and coordination of actions.

Persen and Persen forte

Contains extracts of valerian, lemon balm and peppermint. Available in the form of tablets and capsules. Properties, indications, contraindications and side effects are standard. Recommended doses of Persen: 3-4 tablets three times a day, for sleep disorders - 3-4 tablets an hour before bedtime. Persen Forte take 2 capsules 2 times a day or 2 capsules 1 hour before bedtime. Taking the drug does not depend on food intake. Tablets/capsules should be swallowed whole with a small amount of water. The course of treatment is not limited. Of the special instructions, it should be noted that this drug contains lactose - it is contraindicated in patients with lactose. During pregnancy and lactation, Persen is used after a benefit/risk assessment.


Persen cardio

Available in the form of capsules containing extracts of passionflower herb and hawthorn leaves and flowers. The mild sedative effect of passionflower in this preparation is combined with the cardioprotective (improves heart function) effect of hawthorn. It is used for vegetative-vascular dystonia, increased nervous excitability, functional disorders of the heart, and neuroses. It is recommended to take 1 capsule orally once a day. If necessary, the dose can be doubled. The drug should be taken before meals with water. Duration of treatment – ​​at least 1.5 months. Persen cardio is contraindicated in case of individual hypersensitivity to its components, as well as during pregnancy and lactation. Side effects are standard. Contains lactose - should not be taken by persons intolerant to this substance. There are no data on safety during pregnancy and lactation. During treatment with this drug, it is not recommended to work with serious machinery or drive vehicles.

Relaxil

The composition and properties are similar to Persen. Available in capsules. It is recommended to take 2 capsules 2 times a day or 1 hour before bedtime.

Sedavit

Contains a complex of plant extracts (valerian, hawthorn, St. John's wort, mint, hop cones), pyridoxine and nicotinamide. Available in the form of tablets and oral solution. The active substances of medicinal plants have sedative, anti-anxiety, cardioprotective effects, reduce feelings of fear and mental stress. Vitamins normalize metabolism in nervous tissue. Indications are conditions of constant neuropsychic overstrain, neurasthenia, neurocirculatory dystonia, asthenic syndrome, stage 1 hypertension, menopausal syndrome, etc. Tablets are used 2 pieces 3 times a day. Swallow whole with liquid. If necessary, the single dose can be increased to 3 tablets. If adverse reactions from the nervous system occur, reduce the dose to 1 tablet at a time. The solution is taken 1 teaspoon (5 ml) orally 3 times a day. The dose can be increased to 10 ml per dose. Contraindications to taking the drug are: hypersensitivity to the components of the drug, bronchial asthma, spasmophilia, arterial hypotension, myasthenia gravis, severe liver pathology, diabetes mellitus that cannot be corrected. Side effects occur in isolated cases, they are standard. Persons with hereditary pathologies of carbohydrate metabolism are not recommended to take this drug, since it contains lactose and sorbitol. While taking Sedavit, you should not expose your skin to prolonged exposure to ultraviolet rays.

Sedariston


Passionflower preparations soothe, improve mood and improve sleep.

Available in the form of drops containing alcoholic extracts of St. John's wort, valerian and lemon balm, and capsules consisting of dry extracts of St. John's wort and valerian. The effects, side effects, indications and contraindications are similar to those of previously described drugs with similar composition. Recommended doses of drops: 20 drops. three times a day before or 2 hours after meals, first diluted in liquid. The recommended daily dose of the drug in capsule form is 4 pieces (2 capsules twice a day or 1 capsule 4 times a day) - before meals, with plenty of liquid.

Sedasen and Sedasen forte

Contains dry extracts of valerian, mint and lemon balm. The “forte” form differs from the simple one by containing 2.5 times more valerian extract. We will not repeat ourselves regarding the properties, indications, effects and side effects of these drugs - they are standard. It is recommended to take 1-2 capsules 2-3 times a day or 1 hour before bedtime, swallowing the capsule whole and drinking plenty of liquid. The duration of treatment varies, ranging from several weeks to 12 months. If no improvement in the patient's condition is observed within 2 weeks of taking the drug, treatment should be reconsidered.

Sedafiton

Tablets containing thick extracts of valerian, motherwort and hawthorn. Has a sedative and cardioprotective effect. A single dose for an adult is 1–2 tablets, the maximum daily dose is 6 tablets.

Trivalumen

Capsules containing dry extracts of valerian, peppermint, hops and bean tree. It has sedative, hypnotic and a number of other, less pronounced properties that are not related to the nervous system. Does not cause addiction, does not depress psychomotor functions, and does not impair work ability. Used for insomnia due to nervous and mental fatigue, neurocirculatory dystonia of the cardiac type (accompanied by palpitations, increased heart rate, arterial hypertension, pain in the heart), decreased appetite.

It is recommended to take 1 capsule 2-3 times a day or 1-1.5 hours before bedtime. Duration of treatment is 1–2 weeks. After 10 days, the course of treatment can be repeated. In the vast majority of cases, the drug is well tolerated. If recommended doses are exceeded, side effects such as drowsiness, lethargy, weakness, decreased ability to work and the ability to concentrate, and decreased blood pressure may develop.

Contraindicated in case of increased individual sensitivity, cholelithiasis, hypotensive conditions, depression. It is not recommended to use this drug when working with serious machinery or driving vehicles.

Listed above are the most commonly used sedatives of plant origin in medical practice. We draw your attention to the fact that even taking into account the safety of this group of drugs, if you develop symptoms for which they are indicated, you should not self-medicate, but should immediately seek qualified medical help - only under this condition will the prescribed treatment bring maximum results !

Which doctor should I contact?

To prescribe herbal sedatives, you can contact a neurologist. In addition, they are used in their practice by therapists, pediatricians, cardiologists, gynecologists, and psychiatrists.

The modern rhythm of life suggests that a successful person does not have the opportunity to relax or fully rest. Constant stress, tension, psychological overload and lack of sleep cause the development of pathological processes in the body. Insufficient sleep can also lead to a nervous breakdown. Such symptoms appear especially often in women and people with a hereditary predisposition. Sedative medications help to cope with such a serious condition.

How sedatives work

Sedatives are all medications that are taken to calm and stabilize the central nervous system. Inhibition of processes in the central nervous system has a complex effect:

  • The level of aggression decreases;
  • Irritability disappears;
  • The patient does not feel excessive sensitivity;
  • Heart rate decreases;
  • Sweating decreases;
  • Spasmodic pain recedes.

During treatment, you need to check the compatibility of medications with other medications taken, since the components included in the composition can enhance each other and cause an overdose.

Mild sedatives are available without a doctor's prescription. As a rule, these are dietary supplements or homeopathic remedies. More serious medications are sold only by prescription, and some of them are approved for use only in a hospital setting under the supervision of a specialist.

Indications for use

Sedatives of varying intensity are prescribed to adults and children when diagnosing nervous system disorders.

For adults

Most often, the underlying factors for taking sedative medications are:

  • Rapid irritability;
  • Headaches, the etiology of which is not related to other diseases;
  • Lack of control over emotions;
  • Outbursts of aggression, rage;
  • Sleep disturbance, regardless of the cause of the symptom.

Drugs for sedation are prescribed to people for diseases accompanied by severe itching, burning, pain, that is, in situations where the human body cannot relax in order to rest.

For children

Every parent knows that children are very active. Normally, morning mobility decreases towards daytime sleep, when the child is tired physically and from the impressions received. The same thing happens after lunch. However, in some cases symptoms such as:

  • Anxiety;
  • Tearfulness;
  • Hyperactivity without a break for sleep;
  • Hysterics;
  • Capricious behavior.

If manifestations are not observed often, there is no need to worry - this may be a reaction to the parents’ reluctance to please any whim or a consequence of severe fatigue. But when symptoms appear every day, you need to consult a doctor, as they indicate improper development of the central nervous system.

Sedatives help stabilize the central nervous system and ensure that the child has proper rest. Naturally, these drugs are much gentler than products for adults, but you should not abuse them.

Pregnant

  • Severe anxiety about the health of your baby;
  • Late insomnia;
  • Strong emotionality or impulsiveness at any time;
  • Nervousness caused by lack of vitamins;
  • Constant bad mood.

Many medications can harm the unborn child, so treatment of a pregnant woman with medications throughout the entire period of gestation is carried out only when there is a real risk to the health of the mother or fetus. Typically, pregnant women are prescribed herbal teas, aromatherapy and other methods of finding harmony with their condition.

Sedatives

Medicines are produced in the form of tablets, capsules, drops, and tinctures. A common side effect of drugs in any form and with any composition is mild due to a slowdown in the rhythm of the cerebral cortex. Despite the fact that sedatives are not classified as sleeping pills, they speed up the process of falling asleep due to a decrease in the excitability of the central nervous system.

Regardless of the reasons, it is not recommended to prescribe yourself sedatives - this is done only by a doctor after a comprehensive examination, identifying the cause of the disease, selecting the optimal treatment and focusing on the current state of the body. In addition, if tablets or infusions were previously prescribed to get rid of neurosis or neurasthenia, this does not mean that they will be suitable for treatment next time.

Sleeping pills

Sleeping pills are necessary for patients who suffer from various sleep disorders. The intensity is selected according to the etiology of insomnia and the complexity of its development. Strong sleeping pills are prescribed in rare cases and are available only with a prescription.

Pharmacy kiosks offer a variety of medications to stabilize sleep, with sedative effects of varying strength. Most of them are based on herbal ingredients, but there are completely synthetic formulations for people prone to allergic reactions. Each drug has its own characteristics:

  • Speed ​​of falling asleep;
  • Duration of action;
  • Age restrictions;
  • Recommendations and contraindications;
  • Compatibility with other drugs;
  • Reasons for admission.

Some patients need sleeping pills to get rid of insomnia as a pathological condition, while others need a fast-acting remedy to quickly get used to changing time zones, while others just need to “survive” the flight. Only a neurologist or somnologist will help you choose a medicine after diagnosing the disease and a detailed study of the symptoms.

You also need to understand that some sedatives have a cumulative effect, others are addictive, and an overdose can be fatal. Therefore, you must approach this treatment method with caution, consult your doctor before visiting the pharmacy and strictly follow the dosage prescribed in the instructions. If for some reason the product does not help, you should choose a drug based on other active ingredients.

Sedatives available without a doctor's prescription


In many cases, nervousness and excessive excitability indicate the development of pathological processes, such as:

  • Hormonal disbalance;
  • Disturbances in the functioning of the cardiovascular system;
  • Mental disorder;
  • Diseases of internal organs.

If you ignore these prerequisites and take medicine “for nerves,” there is a chance that the disease will be detected only at a late stage of development, when treatment becomes difficult. For this reason, it is not recommended to take over-the-counter medications to calm nervousness without prior examination. But if such a decision is nevertheless made, it is necessary to study the issue in detail in order to understand what can be expected from taking sleeping pills.

Medicines classified as sedatives have a short list of side effects that are rare. They are not addictive, have an additional analgesic effect, extremely rarely lead to an overdose, and are sold without a prescription. Most often they are used for nervousness, migraines associated with difficult life situations - problems at work, passing exams.

Before buying any sedative, you should read the list of indications, contraindications, and side effects. Particular attention should be paid to compatibility with other drugs. If any existing contraindications are detected, another drug should be chosen.

Sedatives

All sedatives and sleeping pills, as well as some dietary supplements and homeopathic remedies, have a sedative effect. If the problems are not very pronounced, are associated with temporary difficulties or general weakening of the body, for example, after surgery, you can choose names that are not medications.

Taking serious sedatives comes with a number of risks, as they have a long list of side effects and are addictive. Only a specialist can prescribe treatment.

Herbal sedatives

Medicines consisting only of herbal components are among the safest. They are prescribed for treatment for children under 12 years of age, as well as for women during pregnancy and lactation. Taking herbal medications can reduce the negative effect on the kidneys, liver, pancreas, that is, all those organs that “suffer” when treating any disease with medications.

When choosing this method of treatment, it is necessary to take into account that products based on plant extracts are not suitable for everyone. Each of them has its own list of contraindications, the most significant of which are individual intolerance and allergic reaction to the components included in the composition. Therefore, when purchasing even the safest product, according to reviews, you need to carefully read the instructions and make sure that it is suitable for your specific case.

The list of the most effective drugs for patients who do not require strong sedatives includes:


Available in the form of a sachet for brewing or a more effective alcohol tincture. The product normalizes sleep, reduces spasms in the intestinal area, and reduces nervous excitability. It is not recommended to use in large doses, as there is a risk of reducing heart rate.


The medicinal plant, known scientifically as passionflower incarnate, is used to stabilize sleep phases. Preparations based on passionflower relieve convulsions, have a mild analgesic effect, and suppress excessive excitability of the central nervous system. A tincture of passionflower incarnate is prescribed to people with neurasthenia, depression, unreasonable anxiety and sleep disorders.

A well-known folk sedative that even pregnant women are allowed to take throughout their entire period. Motherwort tea has a mild calming effect and makes it easier to go to sleep. An alcohol tincture is prescribed by a doctor, setting a strict course of administration, as it has a more pronounced sedative effect.


Peony-based medicinal tincture is most effective for recovery after a nervous breakdown. It is prescribed to people with pronounced vegetative-vascular dystonia, as well as to neurasthenics. Peony extract can be seen in most existing herbal antidepressants.

Combined herbal remedies

Medicines containing several different herbal components are classified as combined sedatives. They are very popular because they are more effective than regular decoctions and infusions, but they are also sold without a prescription. However, the list of contraindications for such drugs is longer - this must be taken into account when choosing a treatment.

Phytosed

Alcohol soothing infusion based on motherwort. The list of auxiliary components includes lemon balm, sweet clover, and hops. Coriander gives the composition a special smell. Sometimes Phytosed is found in pharmacies in the form of capsules.

Prescribed for minor sleep disturbances, slight nervousness and increased fatigue at the end of the day.

The main advantage of the medicine is a short list of contraindications:

  • Pregnancy;
  • Lactation period;
  • Allergy to components;
  • The need to drive a vehicle.

Take Phytosed one teaspoon up to 4 times a day for a month. Be sure to take the last dose immediately before bedtime. After a month, you should take a break of at least three weeks. Then you can repeat the treatment as prescribed by your doctor.

Phytosedan 1-3


Drugs of the same name with different labels are based on motherwort, but differ in excipients:

  • 1 – oregano, valerian, thyme;
  • 2 – valerian, peppermint, licorice extract, hops;
  • 3 – sweet clover is added to the composition of Phytosedan 1.

The herbal mixture is produced in the form of packaged collection or already packaged sachets. Tea bags are brewed according to the instructions. Otherwise, take 2 large spoons of the composition for 250 ml of boiling water and keep in a water bath for a quarter of an hour. Then take 100 ml up to 4 times a day.

Phytosedan is prescribed for the treatment of VSD, migraines, neurosis and the consequences of menopause. Contraindications – hypersensitivity to the components. Allergic rashes are rarely observed.

Persen

The medicine is based on herbal ingredients such as medicinal lemon balm, valerian and peppermint. Pharmacy kiosks offer the following dosage options:

  • Persen containing valerian 50 ml;
  • Persen Forte with 125 mg of active ingredient.

Persen is prescribed for irritability and depression. Ideal for people exposed to severe stress at work. The drug stabilizes sleep and allows you to rest well, so it is recommended to take it mainly before bed. In difficult cases, take 1-2 tablets up to three times a day for two months.

Person has more contraindications than similar herbal medicines:

  • Fructose intolerance;
  • Hypotension;
  • Pathology of the gallbladder;
  • The period of bearing a child and breastfeeding;
  • Age up to three years.

The annotation for the medicine warns that allergies and constipation may appear as negative manifestations of prolonged treatment. In these cases, you must stop taking it and consult a doctor to select an analogue.

Novo-Passit

Another popular herbal sedative, available in tablet or tincture form. The main composition includes lemon balm, valerian and hops. Auxiliary elements include elderberry, hawthorn extract, guaifenesin and passionflower.

Doctors prescribe Novo-Passit as an anti-anxiety remedy for pronounced neuroses, unreasonable fears and experienced shocks. A positive effect is observed for insomnia, migraine, and psychological dermatosis.

The rich and non-standard composition causes a long list of contraindications:

  • Age up to 12 years;
  • Severe allergic reactions to the components of the drug;
  • Liver pathologies;
  • Dysfunction of the gastrointestinal tract;
  • Epilepsy;
  • Myasthenia.

An overdose or prolonged use of the drug can result in such negative consequences as nausea, drowsiness, dizziness. According to the instructions, take 1 tablet three times a day. If syrup is purchased, 5 ml is enough for one use.

Dormiplant

Tablets of German origin have an extremely simple composition:

  • Melissa extract;
  • Ethanol;
  • Valerian.

It is prohibited to treat children under 6 years of age, persons sensitive to the components, as well as women pregnant and during breastfeeding. It is recommended to take Dormiplant with caution in patients with suspected renal dysfunction.

Ethanol, which is part of the composition, reduces the rate of reactions, therefore, during therapy it is recommended to avoid dangerous work and driving a vehicle.

Among the negative manifestations of long-term treatment, a mild allergic reaction is noted.

One course of treatment lasts about two weeks. At this time, drink 2 tablets half an hour before going to bed and immediately after breakfast.

Alvogen Relax

The Spanish drug is rarely prescribed in Russia due to its high price. However, it has a wide range of indications for use:

  • Frequent stress;
  • Anxiety;
  • Migraine;
  • Mild sleep disturbances;
  • The so-called manager syndrome.

For all its usefulness, Alvogen Relax has only two contraindications - taking other sedative medications and hypersensitivity of the components. The only side effects noted were an allergic reaction due to individual intolerance.

There are two dosage regimens. For stressful situations, you will need to drink Alvogen Relax three times a day, one capsule. To treat insomnia, two capsules at night are enough. It is recommended to drink at least 100-150 ml of water immediately during administration.

Alcohol solutions

Unlike brewing sachets, alcohol solutions have a pronounced sedative effect. They help you quickly relax and slow your heart rate. They are mainly prescribed to hypertensive patients. Most medications are produced in the form of drops that must be dissolved in plain water or washed down.

Despite the quick effect of use, alcohol solutions are not popular because they have a number of significant contraindications. In some cases they are addictive. Most medications containing ethanol negatively affect the speed of reactions, so they should not be used by people with a dangerous profession.

Valocordin

Take Valocordin for neuroses, mild sleep disorders, heart problems, and anxiety.

Long-term use of Valocordin causes drowsiness, depression, rhinitis, conjunctivitis. In difficult cases, diathesis and problems with coordination of movements are diagnosed. Take the medicine only according to the instructions or as recommended by a doctor, without exceeding the course of treatment.

Corvalol

An herbal medicine that has been successfully used as a cardiac sedative for decades. It is based on peppermint. Among the auxiliary components are phenobarbital and ethyl bromisevalerate.

The drug is allowed to be taken for arterial hypertension, VSD, and mild neuroses. Many patients noted that treatment with Corvalol allows them to get rid of intestinal spasms.

The medicine is available in drops or tablets. In the first case, use is contraindicated for children under 3 years of age, and the tablets are prescribed for treatment only in adults. At the same time, drops still remain the predominant form, since they act faster and cause less harm to the liver and kidneys.

Corvalol is not prescribed for:

  • Carrying a child;
  • Breastfeeding;
  • Brain diseases
  • When liver or kidney failure is diagnosed;
  • During partial median myotonia.

Among the consequences of treatment are dizziness, allergic reactions, a significant slowdown in heart rate, and drowsiness. The medicine may be addictive.

Green drops

Drops from the manufacturer MosPharm are better known as “Kremlin” drops, since during the Soviet Union they were popular among officials. Their composition is based on valerian, belladonna, levomenthol and lily of the valley.

Zelenin drops are considered an effective medicine for diseases such as:

  • Intense renal colic;
  • Neurosis;
  • Significant decrease in appetite.

The unusual composition leads to the fact that Kremlin drops have a long list of contraindications. The main ones include the period of pregnancy and breastfeeding, age up to 18 years, various ophthalmological diseases, suspicion of myocardial infarction, gastric ulcer, prostate problems, etc.

With long-term use, addiction may develop and many side symptoms may appear.

Valosedan

The main active component of Valosedan is rhubarb. Valerian, hops and hawthorn have additional effects. Available only in the form of a mixture.

Take the drug for mild nervous disorders or as part of combination therapy. With its help you can get rid of arterial hypertension at an early stage of development and cure insomnia.

The standard side symptoms are dizziness and drowsiness, which disappear if you reduce the dose or completely interrupt treatment. An overdose is represented by the consequences of pronounced alcohol intoxication.

The medicine does not have any special contraindications, except for individual intolerance to the components. When prescribing treatment during breastfeeding, it is necessary to temporarily transfer the child to artificial nutrition.

Valocormid

Treatment with Valocormid should be treated with caution, as it has a long series of contraindications:

  • Glaucoma;
  • Breathing problems;
  • Myocarditis and endocarbitis;
  • Cardiosclerosis;
  • Intolerance to components.

Patients with severe liver or kidney failure are advised to find a safer means of therapy.

Valocormid causes symptoms such as headache, allergies, nausea and vomiting, arrhythmia, myasthenia gravis. During treatment, the dosage is strictly observed, since belladonna tincture is classified as a potentially dangerous component.

Valoserdin

Valoserdin therapy is not carried out:

  • During pregnancy;
  • During breastfeeding;
  • Patients under 18 years of age;
  • With diagnosed liver and/or kidney dysfunction.

Negative consequences of use are slight dizziness or slight drowsiness. With prolonged therapy, clinical reactions such as rhinitis, depression, and impaired coordination of movements are observed.

Sedariston


A medicine based on St. John's wort, lemon balm and valerian is prescribed for the following diagnoses:

  • Increased irritability;
  • Decreased concentration;
  • Nervous excitement;
  • Vegetative dystonia.

Sedariston is contraindicated for people with intolerance to the components, as well as for patients in a state of depression and with depressed central nervous system function. In addition, simultaneous use with certain antiviral, antiepileptic drugs, as well as blood thinning drugs is prohibited.

Long-term therapy causes many negative consequences from the nervous system, gastrointestinal tract, and mental stability. Local manifestations and general disorders are often diagnosed.

Nervoflux

A soft tea based on lavender, lemon balm, pomerand and licorice roots. Allows you to relax with mild sleep disorders and increased nervous excitement.

It has no contraindications or side effects. The consequences of an overdose have not been identified.

Apply Nervoflux up to 3-4 times a day, one cup at a rate of 1 teaspoon of the mixture per glass of hot water.

Bromides

Already from the name it is clear that the main active component of the medicinal group is bromine. It helps slow down processes in the brain, stabilizing the overall nervous state of the body.

Bromine is an inexpensive component, so most drugs based on it are classified in the budget segment. The main disadvantage of therapy is the risk of developing bromism, that is, bromine poisoning, accompanied by rhinitis, cough, allergic rashes, and excessive lacrimation.

Adonis bromine

Anti-stress tablets with the auxiliary spring glycoside adonis. Adonis Bromine significantly reduces the heart rate, so it is contraindicated for angina pectoris and bradycardia. Additional contraindications include age under 18 years, diagnosis of a stomach ulcer, as well as bearing a child or breastfeeding.

Take Adonis Bromine three times a day, one tablet according to the course determined by your doctor.

Bromcamphor


A medicine with an additional active component camphor is prescribed for the following diagnoses:

  • Tachycardia;
  • Labile pressure;
  • Mild parasomnia;
  • Neurosis.

Bromcamphor is contraindicated for children of preschool age, as well as for people with a pronounced allergic reaction to the components of the drug. Caution should be exercised when treating patients with renal and liver dysfunction. Special side effects of long-term use include severe lethargy and dyspepsia.

Other groups

Magnesia

  • Increased excitability;
  • Pain in the uterus;
  • Smooth muscle spasms.

A low dosage will have a sedative effect. As the dose increases, a hypnotic effect is observed. An overdose leads to poisoning, which only calcium chloride will help to cope with.

Phenibut

A strong sedative based on nootropic acid is prescribed for treatment extremely rarely. It is usually used during surgery to enhance anesthesia. In addition, it is used to control psychopathy disorders. Rarely used to treat complex forms of insomnia and neuroses.

Negative symptoms of treatment include dizziness, allergic reaction, and increased anxiety. The maximum course of treatment is 3 weeks.

Afobazole

The tablets are contraindicated for women who are pregnant, breastfeeding, children and adolescents under 18 years of age, as well as people with intolerance.

Therapy according to the course does not cause side effects. Long-term treatment or overdose can cause allergies. The maximum allowed course of treatment is 1 month.

Tenoten

Anti-anxiety lozenges that do not cause drowsiness or inhibited reactions are popular due to their effectiveness and convenient release form. They successfully cope with depression, irritability, stress, and VSD. In some cases, they are prescribed as a prophylactic agent.

Contraindications are limited to age under 18 years, intolerance to components. No side effects were detected even with an overdose. The maximum recommended course of treatment is 3 months when taking up to 4 tablets per day.

Noxiron

A sleeping pill that helps stabilize sleep throughout the night. It works approximately half an hour after administration. A special feature of Noxiron is its compatibility with other sedatives.

Side effects are rare. As a rule, these are allergic rashes, rhinitis, sneezing. The danger of the drug is that it is addictive with long-term treatment.

Homeopathic remedies

Homeopathic medicines are not classified as medicines because they are based on natural ingredients and sweeteners. Some doctors agree that the therapeutic effect of homeopathic remedies is based on self-hypnosis. Despite this, you should not abuse the drugs, as they have their side effects and can negatively affect the function of the kidneys and liver.

Calm down

The release form of the drug is tablets. Their use is relevant in a state of increased nervous excitability according to the instructions for use. Contraindications to treatment:

  • Pregnancy, lactation;
  • Intolerance to components;
  • Age up to 18 years.

The effect of taking it is cumulative. The course of treatment is determined for a specific case, but on average lasts from 1.5 to 2 months. During therapy you will have to stop drinking alcoholic beverages.

Allora

A mild sedative, the effect of which is based on passionflower extract in the composition. Allora is prescribed for severe stress, depression, and insomnia.

The medicine is contraindicated in children under three years of age, as well as in patients with severe sensitivity to plant components. Allora is incompatible with other sedatives and sedatives. During treatment, complete abstinence from alcohol is recommended.

Nervochel

Doctors prescribe the drug as a mild sedative for menopause or developing parasomnia. Children under 3 years of age are not allowed to use Nervochel; however, treatment during pregnancy and breastfeeding is allowed, subject to constant supervision by specialists.

Neurosed

Neurosed helps cope with menopause and increased nervous excitability. It stabilizes sleep and improves the quality of rest.

The dangers of sedatives

All medications, including those available without a doctor’s prescription, have their own list of contraindications, indications for use, side effects, and compatibility with other medications. The doctor makes the appointment according to the current state of health and medical history. It is very difficult to choose a medicine on your own, and improper treatment, a long course or exceeding the dose cause side effects, including death.

If there is a need to take sedatives, it is better to consult a doctor to identify the nature of the disease and prescribe appropriate therapy. This approach will allow you to choose effective treatment and reduce the number of possible side effects.

In modern society it is difficult to live without such means. Almost everyone experiences stressful days: tests, exams, problems at work and in the family, important events, etc.

Sedatives make a person less irritable and more restrained, cope with mood swings, help get rid of anxiety and fall asleep easier.

Doctors often prescribe sedatives in the treatment of any disease, since patients are too worried about their illness and experience severe stress as a result. Before planned surgical operations, a person is also prescribed sedatives.

What medications have a sedative effect?

The following groups of drugs that have a sedative effect are distinguished:

  • tranquilizers;
  • bromides (sodium and potassium salts of hydrobromic acid);
  • sleeping pills;
  • antipsychotics;
  • barbiturates;
  • 1st generation antihistamines;
  • Z-drugs;
  • some antidepressants;
  • natural herbal remedies.


Tranquilizers have a fairly strong sedative effect. In addition, they have anticonvulsant, muscle relaxant, anxiolytic (relieves anxiety), hypnotic and hypnotic (decreases attention) effects.

The use of these drugs is unsafe, as they can be addictive, so a person cannot prescribe them for himself.

Barbiturates are very popular; they are included in Corvalol, Valocardine, and Barboval. But these drugs are also unsafe and can be addictive; they must be taken with caution.

Bromides are widely known bromine-based medications that are good for insomnia and irritability. They are relatively safe, but when accumulated in the body they cause bromism.

Bromism manifests itself in lethargy, lethargy, memory loss, apathy, and decreased libido in men. Skin rashes and itching may occur. The most famous drugs from the bromide group are “Bromcamphor”, “Bromenval”, “Potassium bromide”, “Sodium bromide”.

Antidepressants

Medications such as antidepressants work to reduce or prevent depression. They act on mediators responsible for mood and depression, regulating their concentration in the body.

There are currently three groups of antidepressants: tricyclic antidepressants (TCAs), monoamine oxidase inhibitors, and selective serotonin uptake inhibitors. It is the first group, the drugs of which were synthesized in the 1950s, that provide a pronounced sedative effect.

The most famous tricyclic antidepressants with a pronounced sedative effect: Amyltriptyline, Imipramine, Nortriptyline.

Tricyclic antidepressants increase the amount of serotonin and noripinephrine in the brain. But, at the same time, they block other mediators, which is why they can cause many side effects. Antidepressants of the second and third groups are more modern, have a stimulating effect on the brain, rather than a calming one, and adverse reactions to them rarely occur.

There are also antidepressants that do not belong to any of the listed groups, since their composition and mechanism of action are different. Some of these antidepressants have a calming effect (eg, Trazodone).

Antihistamines

Antihistamines block H1 receptors, relieving the symptoms of an allergic reaction. Medicines in this group are divided into first- and second-generation antihistamines and modern active metabolites. First generation antihistamines have many side effects, one of which is sedation.

The most well-known and used antihistamines:


  • "Diphenhydramine" is a potent drug, sometimes prescribed as a sleeping pill. Often causes side effects;
  • “Diazolin” - the sedative effect is weaker than that of “Diphenhydramine”, in some cases it can even cause excitement in the central nervous system;
  • "Suprastin";
  • "Pipolfen";
  • "Fenkarol" - antihistamines with low antiallergic activity, act as a sedative without a pronounced sedative effect. Used during the period of development of addiction to other sedatives and antiallergic drugs.

Second generation drugs are antihistamines, which have virtually no sedative effect. These include “Semprex”, “Trexil”, “Fenistil”, “Gistalong”. Active metabolites are the most modern medicines, such as “Cetrin”, “Telfast”. These antihistamines act without sedation. They are perfect for people who need to focus their attention on something.

Natural remedies

Medicines based on valerian, lemon balm and motherwort are used as a mild sedative during periods of minor stress, insomnia, and neurosis.

Valerian preparations, although of plant origin, can cause depression of the central nervous system in case of overdose, which is expressed in decreased performance, a depressed state.

Therefore, you should not adhere to the opinion that the more you drink the medicine, the better it will work. Always follow the dosage.

Combination preparations such as “Novopassit”, “Passifit”, “Persen”, “Fitorelax” are also made on a plant basis. They do not act as strongly on the central nervous system as antidepressants or tranquilizers, but they can be purchased at any pharmacy without a prescription from a doctor.

Side effects

Whatever drug you choose, you need to remember that each of the sedatives has side effects. Therefore, before you start taking any remedy, you should read the instructions.