Phlebodia side effects. Phlebodia is an effective angioprotective drug based on diosmin

Phlebodia is a venotonic drug from the group of angioprotectors.

The instructions for use for phlebodia 600 state that the drug helps cope with painful sensations in area lower limbs, swelling, cramps.

Tablets are used during treatment varicose veins veins, chronic venous insufficiency. The medicine increases the tone of blood vessels and veins, normalizes capillary permeability, as well as the process of lymph outflow.

The medicine is released in the form of tablets for oral administration.

Diosmin is an active component of tablets and belongs to the group of angioprotectors and microcirculation correctors. Excipients are silicon, cellulose, talc, iron oxide, beeswax.

pharmachologic effect

The use of tablets will provide the following positive therapeutic effects:

• Angioprotective effect.
• Reduce the stretching of veins and increase their tone, reduce stagnation of venous blood.
• The use of the drug has positive effect per condition lymphatic capillaries, eliminates swelling, improves drainage, normalizes lymphatic pressure.
• Anti-inflammatory effect.
• Antioxidant effect.
• Improving microcirculation, normalizing capillary permeability.

The drug also thins the blood, reduces the risk of leukocytes adhering to the inner wall of blood vessels and the formation of blood clots.

Pharmacokinetics of the drug

The medicine is coated, which dissolves after taking the tablet. Absorption of diosmin occurs from the gastrointestinal tract. The maximum concentration of the active substance in the blood is reached 8-9 hours after taking the tablet, the drug begins to act after 4-5 hours. The medicine retains its therapeutic effect for 3.5 days.

Excretion is carried out along with urine, feces and bile.

Indications and contraindications

Indications for the use of tablets are complex therapy of the following diseases:

• Development of chronic lymphovenous insufficiency.
• The drug can also be used for thrombophlebitis
• Elimination of symptoms of acute hemorrhoids.

After surgery, the drug is used for prophylactic purposes as an auxiliary element of therapy.

The medicine is contraindicated for use during therapy in persons under 18 years of age, during the first 12 weeks of pregnancy, during lactation, or with intolerance to the active or auxiliary components of the tablets.

Dose

The dosage of the drug is determined by a phlebologist or angiosurgeon after a face-to-face consultation and necessary research. Unless a different dosage regimen is prescribed, the tablets should be taken in the morning before the main meal. The daily dose is 1 tablet (600 mg). The minimum course of admission is 60 days. IN further doctor may recommend extending treatment with tablets after a short break.

If the patient has missed one or more tablets, do not use double dose medicines. Further administration of the drug should be carried out according to the usual regimen.

No information is provided regarding overdose. Presumably, the risk of adverse reactions may increase.

It is important for expectant mothers to know how to take phlebodia 600 during pregnancy. The dose of the drug is prescribed by a phlebologist or gynecologist after an oral interview and identification of all alarming symptoms. The drug can be taken from the 12th week of pregnancy, taking into account the balance of benefits and possible risks.

During lactation, it is recommended to refrain from using diosmin-based medications.

Side effects

The drug is well tolerated. In rare cases, the following has been reported:

• Development of gastric disorders: flatulence, acidity disorders, stool disorders.
• Moderate headache.
• Allergic manifestations.

The described adverse reactions are transitory in nature and go away on their own after stopping treatment or adjusting the dose of the drug. If any other negative reactions from the body develop during therapy, you should stop taking the pills and consult a doctor.

The simultaneous use of tablets with alcohol may increase the risk of developing unwanted side effects.

Price

The cost of the drug phlebodia 600 is determined depending on the supplier and the pharmacy network that dispenses the drugs:

• Tablets No. 15 – 580-650 rub.
• Tablets No. 30 – 850-970 rub.

Patients who have received information about how much this medicine costs are wondering: is it possible to find a replacement if necessary? You can discuss with your doctor the possibility of taking the following analogue drugs: Phlebofa, Vazoket, Venolek.

You can buy phlebodia 600 tablets in Moscow without a doctor's prescription. Manufacturers of the drug: pharmaceutical companies Innotera Shuzi and Innotera Laboratories, located in France.

It is impossible to completely cure varicose veins, but it is quite possible to alleviate the condition. One of the effective medications is Phlebodia 600.

Release form and composition

The drug is produced by the manufacturer in the form of tablets. They are sealed in a blister of 15 pieces and then packed in a cardboard box. The box may contain one or two blisters. The tablets themselves are round, biconvex, and pink in color.

Main active ingredient The medication is diosmin. It is contained in the drug at a dosage of 600 mg. The substance diosmin enters the blood two hours after administration.

The maximum concentration of Phlebodia 600 in the blood is achieved approximately 5 hours after administration. In addition, Phlebodia tablets contain talc, colloidal silicon dioxide, MCC, and stearic acid.

Indications for use

When should you take the drug? Tablets are indicated for the following health problems:

• varicose veins;
• lymphovenous insufficiency of the lower extremities chronic type;
• microcirculation disorders.

The drug is also used for pelvic varicose veins.

For varicose veins, Phlebodia 600 is prescribed one tablet once a day. How to take the medicine? The tablets should be taken in the morning on an empty stomach. The course of treatment is 1-2 months, depending on the complexity of the disease. In case of severe varicose veins, which is accompanied by symptoms of lymphovenous insufficiency, the drug should be taken for 4 months.

In the presence of varicose veins complicated by trophic ulcers, the course of treatment can be extended to six months.

If for some reason you miss a dose, you do not need to take double the dose, just continue taking the pills the next day at your usual dose.

Operating principle

Phlebodia 600 has good feedback thanks to its quick effect. Within two hours the drug begins to act, and its effectiveness lasts up to 96 hours. One more unique property The drug is a combination of angioprotector and venotonic action. When it enters the body, it has the following effects on it:

• increases vein tone;
• eliminates stagnation of venous blood;
• is improving lymphatic drainage;
• reduces the permeability of venous walls;
• improves blood microcirculation;
• adhesion of leukocytes to the venous wall decreases;
• the drug has an anti-inflammatory effect.

Contraindications and side effects

Contraindications to taking Phlebodia 600 include:

• presence of allergies;
• chronic kidney and liver diseases.

The person taking the medicine must be at least 18 years of age. In addition, the drug should not be used by nursing women, as well as in the first trimester of pregnancy. In the 2nd and 3rd trimester, the medicine can be taken only if it has been prescribed by the attending physician.

While taking Phlebodia 600, the following side effects may occur:

• headache;
• dyspeptic disorders (heartburn, nausea, abdominal pain, flatulence, diarrhea);
• allergic reactions.

If you experience any symptoms while taking the drug side effects, you should immediately stop taking it and consult your doctor.

Analogs

There are many analogues of Phlebodia 600, but they are all inferior to the drug in various respects.

Phlebodia how much to take

Among the methods of treating varicose veins and chronic venous insufficiency (CVI) in last decades All higher value acquires conservative pharmacotherapy.

One of the most effective areas of therapy is the use of flavonoids - angioprotective and venotonic substances, which:

• strengthen the fibrous matrix of the venous walls;
• increase the contractility of muscle cells in veins;
• activate lymphatic drainage;
• strengthen blood capillaries, preventing the “effusion” of fluid from surrounding tissues.

Diosmin preparations, including Phlebodia 600, occupy one of the key positions in the pharmacotherapy of diseases of the venous and lymphatic systems.

Phlebodia 600 is a drug designed to increase the tone of small-caliber veins, improve lymphatic drainage and venous outflow of blood

The pharmacological properties of Phlebodia 600 were established back in 1978, at which time it began to appear on sale, first in Europe. Since then, numerous studies and observations have been carried out on groups of patients taking Phlebodia, which made it possible to establish high efficiency and drug safety.

The active substance of "Phlebodia" is a semi-synthetic (synthesized from natural raw materials of citrus plants) flavonoid diosmin, of which there are 600 mg per tablet. This is the standard recommended daily dose of diosmin for CVI. Auxiliary ingredients of "Phlebodia" are: cellulose MK, talc, stearic acid, silicon dioxide. The shell contains hypromellose, macrogol 400 stearate, wax, E904, E1520, E171, red cochineal A (E124), E172.

Phlebodia with varicose veins:

1. Increases the tone of small-diameter veins without producing a vasoconstrictor effect on the arteries.
2. Increases the reactivity of venous muscle cells to norepinephrine and, accordingly, their contractility.
3. Strengthens the walls of capillaries and reduces their permeability.
4. Improves lymphatic drainage and relieves swelling of the legs.
5. Partially blocks the inflammatory response and reduces venous pain:

• reducing the ability of leukocytes to attach to the endothelium of the vein and their migration to nearby tissues;
• inhibiting synthesis free radicals and prostaglandins.

1. Inhibits the synthesis of thromboxanes, reducing thrombus formation.

Leg pain, swelling and heaviness gradually decrease, spider veins on the skin dissolve and become rarer

Clinical studies have recorded significant reductions in the manifestations of CVI (edema, venous pain, convulsions, sensory disturbances) in at least 85% of patients at various stages of the disease. There was a pronounced positive trend trophic ulcers(in 67% of observed cases - complete healing, in 25% - a reduction in the area of ​​ulcers by at least half).

• symptoms caused by venous and lymphatic insufficiency (heaviness in the legs, venous pain, cramps, swelling, trophic disorders);
• as part of complex treatment for hemorrhoids.

• allergy to substances in the medication (usually to the dye “Red Cochineal A”);
• breastfeeding (there is no information on the effect of the drug in milk on the child).

Possible side effects:

• allergies (usually urticaria);
• heartburn, nausea, stool disorders;
• vegetative-vascular symptoms – headache, episodes of dizziness (rare).

While taking Phlebodia 600, the following side effects may occur: allergic reactions

How to take Phlebodia for varicose veins

In the absence of complications of CVI (thrombophlebitis, trophic ulcers), it is recommended to take Phlebodia 600 for 2 months. In complicated cases, the duration of treatment is determined by the doctor: for example, for trophic ulcers, the course of treatment can last up to six months. Regardless of the severity of CVI, the daily dose is 1 tablet of 600 mg.

It is advisable to take Phlebodia with meals, which reduces the likelihood of heartburn and nausea.

Note: the pharmacy chain sells “Flebodia” cream-gel containing diosmin, positioned as a cosmetic product produced by JSC “Dzintars”. You can also try.

“Phlebodia” for varicose veins of the pelvis

In women, dilatation of the internal veins of the small pelvis of greater or lesser severity is quite common. Varicose veins of the pelvis are often masked gynecological diseases, manifested by constant pelvic pain, menstrual irregularities, pain when gynecological examination and during sexual intercourse. Pain also bothers postmenopausal women. Ultrasound allows diagnosing the dilation of the pelvic veins. The diagnostic criterion is an increase in the diameter of the main veins of the small pelvis.

It is also important to note that this drug does not treat the manifestations of varicose veins, it only eliminates the symptoms of venous insufficiency and maintains the condition of the vascular walls

Clinical studies of the use of "Phlebodia" standard scheme(1 tablet per day for 2 months) showed a marked decrease in the diameter of the dilated pelvic veins and an increase in the flow rate in them in 75–84% of patients, regardless of the stage of the disease, as well as a subjective improvement in well-being. For varicose veins of the pelvic veins during periods of exacerbation, it is advisable to undergo a course of treatment that includes venotonics - including Phlebodia 600. And reasonable physical activity and performing a set of therapeutic exercises should become the rule of the patient’s life.

Pregnancy is not a contraindication to taking Phlebodia 600. Harmful influence for almost 40 years of use of the drug has not been recorded on a pregnant child or on the condition of a pregnant woman. 2-3 weeks before giving birth, Phlebodia is stopped and not resumed while the woman is breastfeeding.

special instructions

"Phlebodia" can be prescribed for placental insufficiency, for the prevention of bleeding during contraception using intrauterine device, as well as after surgery to remove varicose veins.

What is better for varicose veins - Troxevasin or Phlebodia? Troxevasin has a slightly different spectrum of action - it is an antiplatelet agent. It is used both as a venotonic and for resolving blood clots and hematomas, preventing the formation of blood clots (trauma, thrombophlephitis). Can be used both internally and topically. The appropriateness of using Troxevasin is determined by the doctor. Joint use is also possible: “Phlebodia” internally, “Troxevasin” gel externally.

Analogues of "Phlebodia 600" are two-component venotonics (diosmin + hesperidin): "Detralex", "Venarus", as well as tracing paper with "Phlebodia" - "Phlebofa" (RF) with a minimum excipients and without dyes. All these drugs have a similar mechanism of action and comparable effectiveness. "Phlebofa" is a good alternative for people with intolerance to the excipients of "Phlebodia 600".

Phlebodia 600 is sold freely, without a prescription. Price 30 tablets from 940 rubles or from 252 hryvnia. “Flebofa” in Russia costs about 900 rubles.

Reviews of Phlebodia 600 are positive from both doctors and patients. Many patients indicate that the above analogues are better suited for them. This is a matter of individual tolerance and personal preference, since therapeutic effect“Phlebodia 600” and “Detralexa”, “Venarusa”, “Phlebofa” are almost the same.

Phlebodia 600

Description current as of 02/04/2017

• Latin name: Flebodia 600
• ATX code: C05CA03
• Active ingredient: Diosmin (Diosmin)
• Manufacturer: Innothera Chouzy (France)

Compound

Granulated diosmin (the main active substance of the drug), which corresponds to purified anhydrous – 600 mg.

• talc;
• colloidal silicon dioxide;
• stearic acid;
• microcrystalline cellulose;
• dye mixture – red cochineal (Ponceau 4R), titanium dioxide, propylene glycol, red and black iron oxide;
• opaglos 6000 – palm and beeswax, gum lacquer, 95% ethanol.

The protective covering film consists of:

Release form

Biconvex tablets round shape, covered with a pink shell (protective film type Sepifilm 002). In cross-section they appear as a gray-brown core with a surrounding light mantle. Packaged in 15 pieces per blister, cardboard box, one or two strip packaging.

Pharmacological action

The main effects of the drug are aimed at the venous bed:

• reduces the distensibility of veins;
• tones the vascular wall;
• strengthens the wall of capillaries, significantly preventing the possibility of their damage;
• relieves to a certain extent venous stagnation;
• increases microcirculatory resistance;
• reduces the permeability of venous capillaries.

The phlebotonic effect of the active component is dose-dependent, that is, the manifestations of the biological effect are directly proportional to the amount of the drug taken.

Phlebodia also affects lymphatic vessels– significantly increases the frequency of capillary contractions, thereby increasing their functional capacity (lymphatic drainage increases), reduces lymphatic pressure, and expands the density of the vascular bed.

The drug improves blood supply to the skin, as it promotes facilitated diffusion of oxygen and perfusion in the epidermal integument, and has a stimulating effect on the microcirculatory bed.

Separately, it should be noted that Phlebodia affects active ingredients biological nature:

• enhances the vasoconstrictor effects of adrenaline, norepinephrine;
• prevents the release of free radical elements, prostaglandins and thromboxanes;
• reduces the adhesion of leukocytes to the walls of the venous bed;
• reduces the amount of free superoxide anions;
• reduces redistributive migration of whites blood cells into paravenous tissues.

Phlebodia tablets are quickly absorbed from the gastrointestinal tract (taken orally). It is detected in plasma after two hours, and the maximum concentration of the drug in the blood is observed five hours after using the drug.

Diosmin is evenly deposited both in the vena cava and in the subcutaneous veins. vascular bed lower extremities or in other tissues. The active components are excreted mainly through the kidneys (about 80 percent of a single dosage), to a lesser extent with feces (about 11 percent) and bile (2.4 percent).

Indications for use

• chronic venous insufficiency;
• varicose veins of the saphenous veins of the lower extremities;
• feeling of heaviness in the legs, especially in the evening;
• initial stages of development of hemorrhoids or hemorrhoidal crisis;
• prevention and treatment of lymphatic insufficiency;
• burning in the lower extremities in a horizontal position;
• microcirculation disorders;
• increased fragility capillaries.

Contraindications

• intolerance, hereditary idiosyncrasy or individual hypersensitivity to constituent components medicine;
• lactation period breastfeeding for young mothers;
• age category under 18 years.

Side effects

The medicine Phlebodia is usually well tolerated, providing a maximum therapeutic effect without side effects. However, in clinical practice some qualified specialists Such undesirable reactions have been described as:

Such side effects do not require treatment and go away on their own after a short break in conservative therapy.

Instructions for use Phlebodia 600 (Method and dosage)

The tablets are used orally, regardless of food intake, physical activity and periods of wakefulness. The treatment regimen is prescribed individually by the attending physician or a qualified pharmacist, but it usually follows one of the three most tested methods.

If the medicine is used in the treatment of varicose veins or chronic insufficiency of the venous bed of the lower extremities, then daily dosage The drug is 1 tablet per day. The course depends on the pathophysiological stage of the disease: the initial stages of development require taking the drug for two months, and later stages - three to four months. In the presence of trophic changes in the skin (necrotic ulcers, like extreme degree development of pathology) the course is extended to six months. They will recur, treatment may be every two to three months.

The instructions for Phlebodia 600 during exacerbation of hemorrhoidal inflammation of the venous cavities of the rectum are much easier to remember. Prescribed 2-3 tablets per day for a week for relief acute condition. Further, if necessary, the course is extended with one tablet per day for two to three months.

During the second and third trimester of pregnancy, the drug helps get rid of chronic lymphovenous insufficiency if taken 1 tablet once a day. It is recommended to undergo a therapeutic course under the supervision of qualified specialists, that is, when inpatient treatment. Sanitation should be stopped two to three weeks before birth, which should be reported to the attending physician.

Overdose

Symptoms increased concentration The drug has not been registered in blood plasma.

Interaction

No significant effects reported when used together medicines with Phlebodia tablets.

Terms of sale

The drug is on free sale, that is, it is dispensed at pharmacy kiosks without presenting a prescription form.

Storage conditions

Tablets should be stored in a dry place, out of reach of young children. age category, at room temperature up to 27 degrees Celsius. Do not leave the medicine exposed to direct or reflected sunlight.

Best before date

special instructions

When treating an acute hemorrhoidal crisis, you should be observed by a proctologist and conduct regular additional studies, since the drug may not have its pharmaceutical effect immediately, which is fraught with deterioration and progression pathological process up to the prolapse of inflamed venous cavities from the rectum. In the absence of a rapid effect, therapy is supplemented with specialized drugs with hemodynamic and tonic effects.

Synonyms

Analogues of Phlebodia 600

Angio-protectors are a large group pharmacological drugs, the action of which is aimed at strengthening the walls of the macro- and microcirculatory bed, preventing venous stagnation and vascular insufficiency, pathophysiological effect on lymphatic vessels and biologically active substances that regulate these indicators.

So, besides Phlebodia tablets, such drugs as Vasoket, Diosmin, Diovenor are widely used. The range of their applications is in many ways similar to Phlebodia, but the price of analogues can vary greatly. For example, Vasoket costs almost twice as much in the territory Russian Federation, which is explained by the pharmacokinetic properties of the drug.

Separately, it should be noted such a drug as Detralex from the group of venotonic drugs based on diosmin. On pharmaceutical forums, users often argue which is better, Detralex or Phlebodia 600, because the indications for use, pharmaceutical action and therapeutic course of administration are practically no different. The secret lies in the unique technology of industrial processing of the main active substance in Detralex tablets. Micronization ensures more complete and rapid absorption of the drug from the gastrointestinal tract, thus, the maximum plasma concentration is observed within three to four hours after oral administration. Detralex also undergoes a longer period of biotransformation with the formation of phenolic acids, due to which its half-life is slightly more than eleven hours.

Phlebodia during pregnancy

The drug participated in clinical studies for teratogenicity, where it showed negative result, that is, no harmful effect on the developing fetus and the body of the expectant mother was identified. However, to avoid unwanted manifestations or accidental involution, a course of treatment is prescribed only after the twelfth week, when the initial shoots of vital tissues and organs have already formed.

Reviews of Phlebodia 600 during pregnancy from patients confirm the positive therapeutic effect of conservative treatment. Unpleasant sensations associated with congestion in the venous bed are significantly reduced, which contributes to an easier course of pregnancy. Also, satisfied mothers note an improvement in blood circulation in the skin, the skin looks healthier and more natural after the treatment.

Reviews about Phlebodia 600

Reviews of Phlebodia for hemorrhoids confirm the excellent pharmacological effect of the drug. The pathophysiological effect of the drug allows for relatively short time conservatively treat inflammation of hemorrhoidal cavities even in the most advanced stages. The tablets also help mitigate the impact of acute crises, which has a positive effect on the general condition of the body.

Expectant mothers who undergo treatment for chronic lymphovenous insufficiency during pregnancy are also completely satisfied with the drug. Phlebodia allows you to get rid of the unpleasant sensations that inevitably accompany venous stagnation, which greatly facilitates the physiological pregnancy of a child. Separately, it should be noted that due to more active blood supply skin and venotonic effect, Phlebodia has a cosmetic effect on the woman’s body.

Reviews from doctors who use the drug Phlebodia in their clinical practice characterize the drug on the good side, because the pharmaceutical effect occurs relatively quickly. Among similar angioprotectors, tablets take second place in this parameter. Also rare is the development of side or adverse reactions, which also resolve without special drug intervention, gives one hundred form points over any other venotonic agent of general therapeutic action.

Price Phlebodia 600, where to buy

The price of Phlebodia 600 in the Russian Federation is rubles for a small package (one contour blister - 15 tablets). A medicine designed for a longer therapeutic course (30 tablets in a double cell package) can be purchased in rubles.

In Ukraine, such pills for hemorrhoids can be bought a little more expensive. For example, big set Phlebodia (30 tablets) costs almost 300 hryvnia, and a small one costs hryvnia.

Phlebodia 600

Release forms

Storage: 15-25C (room temperature)

Shelf life: 36 months.

Instructions for phlebodia 600

Phlebodia 600 (active ingredient - diosmin) is an original venoprotector from the French pharmaceutical company Laboratory Innotek International. The drug has a venotonic effect (dose-dependently increases their tone, reduces distensibility, prevents venous stagnation), accelerates the outflow of lymph, thereby ensuring the implementation of the drainage function (tons and increases the frequency of contraction of the muscular membrane of the lymphatic capillaries, increases their functional activity, reduces pressure in the lymphatic bed) , stimulates blood flow in the capillary bed (dose-dependently increases vascular resistance, reduces the permeability of capillary walls), prevents the adhesion of leukocytes to the walls of veins and inhibits their movement into paravenous tissue, improves the diffusion of molecular oxygen and promotes oxygenation of skin tissue. In addition to this, phlebodia 600 exhibits an anti-inflammatory effect, enhances the vasoconstrictor effect of catecholamines, blocks the reproduction of free radicals, the synthesis of inflammatory mediators and allergic reactions of prostaglandins and thromboxane. The drug is quickly absorbed from the gastrointestinal tract and enters the systemic circulation in therapeutically significant concentrations within 2 hours from the moment of administration. The maximum concentration of the active substance in the blood plasma is observed 5 hours after administration. The drug is evenly distributed and accumulates throughout the walls of the vena cava and superficial veins of the legs, as well as, to a lesser extent, in the internal organs (kidneys, liver, lungs). The accumulation of phlebodia 600 and its metabolites in the vessels of the venous bed reaches its highest level at 9 hours after oral administration and persists for 4 days. The main part of the drug is excreted by the kidneys, the remaining amount is excreted through the intestines.

Phlebodia 600 is available in tablet form. Before starting a course of medication, you should consult a specialist. At varicose veins with localization of the pathological process in the veins of the lower extremities, as well as with swelling, pain and cramps resulting from chronic lymphovenous insufficiency, the drug is taken on an empty stomach, 1 tablet per day.

The duration of treatment is usually 2 months. For acute hemorrhoids (or exacerbation of chronic) phlebodia 600, take 2-3 tablets per day with meals for 1 week. If for some reason a dose of the drug is missed, you should not compensate for the omissions by taking additional doses (pharmacotherapy continues as usual at the same doses). Treatment of acute hemorrhoids should be comprehensive (in other words, not based on one drug). If the clinical effect is not sufficiently pronounced, the patient should be referred to additional examination and make adjustments to treatment.

The effectiveness of Phlebodia 600 has been demonstrated in a number of clinical studies, the largest of which involved about 7,000 thousand patients. Within this study Participants took 1 tablet of the drug per day (in acute cases - 2 tablets). Patients were subjected to medical examination before and at the end of the first month of treatment. In general, observation lasted for 2 months. Study participants were instructed to avoid other phlebotonics and to avoid significant adjustments to their lifestyle and routine habits (including dietary preferences and physical activity level). Received upon completion clinical trial The results made it possible to state the high therapeutic effectiveness of phlebodia 600 and determine the optimal ways to use the drug. The drug showed its best side, surpassing its competitors in the pharmacological “niche”. Thus, with the use of phlebodia 600, more than 80% of positive outcomes were obtained, while for other venotonics this indicator did not exceed 40%. It was noted that the effectiveness of therapy depends on its duration. Thus, received by the end of the first month of the drug course good results provided that you continue to take the drug, they transform into excellent results.

Phlebodia 600

The drug for the treatment of varicose veins Flebodia 600 is prescribed for poor circulation and swelling of the lower extremities; it has anti-inflammatory and venotonic effects. It can be prescribed during pregnancy (during the second and third trimester), for the prevention of lymphovenous insufficiency, as well as for the treatment or prevention of hemorrhoids.

Preparation Phlebodia 600

Phlebodia tablets are intended for the treatment and prevention of varicose veins, a disease in which elasticity is reduced. venous vessels, thinning of their walls occurs, leading to venous stagnation and vascular insufficiency. The disease affects not only the lower extremities, but also the vessels of the rectum. This form is called hemorrhoids. The drug restores vascular tone, improves blood circulation, and has an anti-inflammatory therapeutic effect.

Composition and release form

Release form Phlebodia 600 is a round, convex, film-coated tablet for oral administration. Packaged in contour cells of 15 pieces, two cells per package. Each tablet contains 600 mg of diosmin - active active substance drug. Auxiliary components and their percentage in the composition of the medicinal product:

Pharmacodynamics and pharmacokinetics

The pharmacological effect of Phlebodia is directed towards the venous bed and is caused by the active substance diosmin. It strengthens vascular walls veins and capillaries, reduces their permeability, prevents venous insufficiency. Acts on lymphatic vessels, increasing the frequency of capillary contraction, reducing lymphatic pressure. The phlebotonic effect manifests itself in proportion to the amount of the drug taken.

Phlebodia tablets are absorbed gastrointestinal tract, the maximum concentration of the main component in the blood plasma is observed five hours after administration. Diosmin is evenly distributed in the vena cava, subcutaneous vascular bed of the legs, and other tissues. Metabolized by the kidneys, about 80% of a single dose taken. It has virtually no systemic effects on other organ systems.

Indications for use

The medicine Phlebodia 600 is prescribed as part of the complex therapy of venous diseases, with lymphatic insufficiency. The use of the drug is practiced in the following conditions:

• varicose veins of the lower extremities;
• swelling and feeling of heaviness in the legs;
• chronic venous insufficiency;
• symptoms of hemorrhoids;
• increased fragility of capillary vessels, expressed in the appearance of vascular networks on the skin.

Phlebodia 600 – instructions for use

Phlebodia tablets are taken orally, regardless of meals or time of day. The treatment regimen is selected by the doctor in accordance with the diagnosis, stage of the disease, manifestation of symptoms and individual characteristics the patient's body. The manufacturer indicates the following treatment regimens in the instructions for use:

• varicose veins and chronic venous insufficiency: 1 tablet per day, for 1-2 months at the initial stage, 3-4 months during periods of exacerbations and advanced stage diseases;
• for exacerbations of hemorrhoids: 2-3 tablets per day during the first week, then - one tablet until symptoms disappear completely.

special instructions

Phlebodia tablets for varicose veins may not have a quick effect during exacerbation of an acute hemorrhoidal crisis. To avoid aggravation of the condition and prolapse of inflamed nodes from the rectum, you should undergo treatment under the supervision of a proctologist, who, if necessary, will supplement the therapy with hemodynamic and tonic drugs. Do not take during the first trimester of pregnancy.

During pregnancy

During the second and third trimesters of pregnancy, Phlebodia is prescribed to prevent lymphovenous insufficiency. The duration of the course is determined by the specialist caring for the patient; therapy is carried out in a hospital setting under the supervision of doctors. The maximum daily dose of the drug is 1 tablet per day. Admission is stopped no later than 2-3 weeks before the expected date of birth.

Drug interactions

The drug Phlebodia is well tolerated by the body and does not have a systemic effect on the activity of the substances of other drugs. With complex drug therapy for varicose veins and treatment of hemorrhoids, immunomodifying and anti-inflammatory drugs are prescribed along with the drug. According to expert reviews, no significant negative effects or consequences of co-administration were identified.

Phlebodia and alcohol

To avoid negative consequences, it is better to avoid drinking alcohol during the treatment period. Joint simultaneous administration is strictly prohibited. However, you should take into account the time factor during which you should not take Phlebodia tablets after drinking alcohol:

• men: 18 hours before and 8 hours after drinking alcohol;
• women: 24 hours before and 14 hours after drinking alcohol.

Phlebodia 600 is a medicine that supports vein tone, made on the basis of granulated diosmin. Diosmin is a semi-synthetic flavonoid, the raw material for the production of which is an extract of the plant Teucrium gnaphalodes from the genus Dubrovnik, which grows wild in Iberian Peninsula. An analogue of diosmin is hesperidin. Both drugs, in addition to the treatment of varicose veins, are also used in the treatment of hemorrhoids.

Instructions for use

A remedy for the treatment of vein diseases Phlebodia 600 - instructions for use are provided for the purpose of familiarization by patients before starting therapy and prevention. It must be read before starting a course of treatment with this drug so that it is convenient and safe to use.

Pharmacological effect

The effect of the drug is to reduce the distensibility of the veins, have a tonic effect on the vascular walls, strengthen the walls of the capillaries and reduce the likelihood of injury, eliminate congestion in the veins, as well as increase the resistance of the microcirculatory bed, i.e. improves lymphatic drainage.

When taking Phlebodia 600, venous capillaries become less permeable, and veins become much less distensible. The drug can also remove or reduce inflammatory processes and promotes better skin saturation and subcutaneous tissue oxygen. It also has a vasoconstrictor effect, especially in combination with adrenaline and norepinephrine. Thanks to Phlebodia 600, the synthesis of free radicals and the production of thromboxane and prostaglandins are blocked. This is why the condition of the veins improves and reduces the risk of blood clots, which pose a real danger to everyone internal organs– heart, lungs, brain.

Composition and release form

The active ingredient is granulated diosmin (anhydrous purified diosmin).

The composition of the medicine, in addition to the main active ingredient, includes: talc, colloidal silicon dioxide, stearic acid, microcrystalline cellulose.

Shell: protective film type Sepifilm 002 (hypromellose, microcrystalline cellulose, macrogol stearate 400), dyes - mixture of type Sepiperse AP 5523 (dioxypropane, hypromellose, titanium dioxide, red cochineal (Ponceau 4R), black iron oxide, red iron oxide), Opagloss 6000 (palm and beeswax, gum lacquer, ethyl alcohol 95%).

Phlebodia 600 - tablets, convex on both sides, round in shape, covered with a pink coating.

The blister contains 15 tablets of a remedy for varicose veins. There can be 1, 2 or 4 blisters in a cardboard box. Weight of 1 tablet – 600 mg.

Indications for use

Varicose veins in the legs, as well as lymphovenous insufficiency, impaired microcirculation, increased fragility of microcapillaries, a feeling of heaviness in the legs, burning in the legs when lying down are the most common situations when it is worth taking Phlebodia 600.

In addition, the medicine can help with hemorrhoids, since this problem is also directly related to the disorder venous circulation in the rectal area.

Contraindications

Pregnancy and breastfeeding, since the effect of Phlebodia 600 in pregnant and lactating women has not been studied, although in exceptional cases at severe forms varicose veins, the doctor may prescribe the drug to a pregnant woman, but the medicine should not be taken without a doctor’s recommendation, because its effect on the fetus and expectant mother not researched. The effects of taking Phlebodia 600 in lactating women are also unknown (this applies to both the effect on the woman’s body and possible consequences for the composition of milk and the health of the baby feeding on it).

Various forms of fermentopathy, idiosyncrasy and allergies associated with intolerance to the components of the drug.

Dosage

Varicose veins and discomfort in the legs. In this case, you need to take 1 tablet per day for two months. The medicine is taken every morning on an empty stomach, washed down with a tablet a small amount water.

Haemorrhoids. Treatment lasts a week. You should take 2-3 tablets per day. This is done while eating.

Overdose

There is no information about the symptoms of a drug overdose. Mouth random intake large quantity tablets, you need to rinse the stomach and give the patient enterosorben (activated carbon, Enterosgel).

Side effects

Despite the fact that in most patients taking the drug does not cause any unusual sensations or deterioration in health, during treatment with Phlebodia 600 in exceptional cases the following are possible:

• bad breath, nausea and other gastrointestinal disorders;
• manifestations of allergies - swelling, itchy skin, skin rashes;
• the appearance of dizziness and headaches.

In these cases, you need to take a break from taking the medicine so that the unpleasant symptoms go away. You may need medical advice. It will make sure that the patient does not have any contraindications to taking the drug, for example, allergies, or change the treatment regimen to a more suitable one in each specific case. It is undesirable to neglect visiting a doctor if side effects occur, because otherwise the harm from using the medicine may exceed the beneficial effect.

special instructions

Before you start using the drug, as well as if side effects occur during treatment with Phlebodia 600, you should visit a doctor. In addition, consultation with a physician is necessary in cases where the effect of taking the drug does not occur. In these cases, the treatment regimen may need to be adjusted to achieve required result and improving human health.

Storage: terms and conditions

The storage temperature of the drug should not exceed 25 - 30ºС. The medicine should not be stored for more than 3 years. The place where the medicine is stored should be out of the reach of children.

Release from pharmacies

A prescription is not required when purchasing the drug.

Price

The drug is widely available for people suffering from varicose veins. The following medication packages are available:

1. 15 tablets (1 blister) - costs from 519 to 584 rubles;
2. 30 tablets (2 blisters) – cost ranges from 894 to 900 rubles;
3. 60 tablets (4 blisters) - priced from 1600 to 1662 rubles.

Phlebodia 600 can be ordered from online pharmacies, as well as purchased in all regular pharmacies in the country.

Analogues of the drug Phlebodia

Vasoket, Phlebofa, Diovenor 600, Diosmin are drugs containing the same main active ingredient as Phlebodia 600.

Other drugs for the treatment of varicose veins are alprostan, agapurin, betaver, aescin, betaserc, vasaprostan, vasonit, etamzilat, aescusan, venolek, antistax, anavenol, ascoturin, troxevasin, troxegel, phleboton.

The most famous analogue of Phlebodia 600 in terms of active substance is Diovenor, which also contains 600 mg of diosmin

Just like Phlebodia 600, it is taken every morning, 1 tablet for varicose veins, and a course of 3 tablets is taken daily if the drug is prescribed for the treatment of hemorrhoids. In addition, Diosven containing 500 mg of diosmin is often purchased instead of Phlebodia 600. It is also a remedy for the treatment of hemorrhoids and varicose veins, taken according to a regimen similar to Phlebodia 600.

Phlebodia 600 - instructions for use

The drug "Phlebodia 600" is one of the most popular medications, aimed at improving the condition of the veins, as evidenced by numerous reviews from specialists. It is used in the treatment various stages varicose veins, as well as hemorrhoids - diseases associated with stagnation of venous blood and pathological expansion of veins. This medicine is aimed at combating the main cause of venous stagnation, has a venotonic effect, strengthens the walls of blood vessels and increases their elasticity. The Gorzdrav pharmacy provides the opportunity to purchase this drug at a favorable price.

Components and description of the drug

The composition of the venotonic "Phlebodia" includes an active substance called Diosmin, which provides the medicinal properties of the drug. Diosmin is included in the medication in the amount of 600 mg, hence the name “Phlebodia 600”.

Diosmin as an active ingredient medicinal substance, performs the following functions:

• increased venous tone;
• stimulating blood circulation;
• reduction of venous stagnation;
• improvement of capillary resistance;
• beneficial influence for lymph outflow;
• improving blood supply to tissues;
• prevention of inflammatory processes.

The composition of the drug also includes additional components: microcrystalline cellulose, talc, stearic acid, as well as silicon dioxide, which complement the active substance Diosmin.

The release form of this medication is tablets, they have a rounded shape. convex view and covered with a pink shell. The shell contains a mixture of dyes, beeswax, propylene glycol and titanium dioxide. The tablet form ensures ease of use of the medicine. One package of Phlebodia 600 can contain from one to two blisters with tablets (15 pieces each). The packaging itself is cardboard, and instructions for using the medicine are also included.

The manufacturer recommends storing the medicine in a place protected from direct sunlight. The storage temperature should not exceed 30 degrees plus, as the drug may lose its properties and will not be suitable for use. The medicine can be stored for no more than 3 years, otherwise the manufacturer does not guarantee the expected effect. The country of release of the medicine is France.

When is it appointed?

The angioprotective properties of the drug, which are provided by the active substance Diosmin, determine the scope of application of this drug.

Indications for use of Phlebodia 600 may be as follows:

• the presence of varicose veins in the legs;
• chronic venous insufficiency;
• haemorrhoids.

The medicine effectively acts on blood vessels, increasing their elasticity and preventing excessive distensibility. In drug therapy for varicose veins and hemorrhoids, the main goal is to increase the tone of the veins, since weakened vessels are prone to pathological expansion under the influence of high blood pressure blood. As a result deoxygenated blood accumulates in deformed vessels, causing pain and swelling of the lower extremities. Diosmin, as the main component of the drug, improves blood circulation and stimulates lymph circulation, eliminating swelling and bursting pain in the legs. Diosmin also reduces the distensibility of veins, prevents venous congestion, regulates oxygen saturation of tissues, strengthens capillaries and fights inflammation. IN complex treatment Phlebodia 600 tablets contribute quite quick deliverance from painful and uncomfortable symptoms of varicose veins, as well as worsened hemorrhoids.

This remedy is also successfully used in the postoperative period for excision of pathologically altered veins. The drug helps prevent bleeding after surgery and rehabilitation therapy.

The maximum effect from Phlebodia, presented in the wide range of the Gorzdrav pharmacy, will be achieved if you follow all the doctor’s recommendations regarding the treatment of dilated veins:

• diet;
• use of external venotonic agents;
• normalization of blood flow through regular exercise.

A course of treatment

Drug treatment using Phlebodia 600 is part of the complex therapy of venous insufficiency, prescribed by a doctor after diagnostics and an accurate diagnosis. The dosage and duration of the therapeutic course are determined by the attending physician depending on the specific disease and general condition patient. The instructions for the tablets contain information about how long and in what quantity to take them in various cases:

• with exacerbation of hemorrhoids. The tablets must be taken daily for 7 days. The recommended daily dosage is 2 to 3 tablets, which should be taken with meals. The drug helps reduce venous congestion in hemorrhoidal veins, helps reduce pain and fights inflammation. If a week after use, the symptoms of hemorrhoids do not disappear or decrease, it is necessary to consult a doctor and adjust the treatment;

• for venous insufficiency and varicose veins. It is recommended to take 1 tablet daily, preferably before breakfast. The duration of the course depends on the severity of the disease and the stage of its development: at initial stages varicose veins therapy lasts 2 months; in severe cases, you will have to take the pills for up to 4 months; if there are trophic ulcers on the legs, the duration of taking the medicine is up to 6 months. If necessary, treatment is repeated after a break of 2-3 months.

As a result of systematic intake of the venotonic “Phlebodia 600”, the veins acquire the necessary tone, after which they become less susceptible to stretching and various damages. Accordingly, the symptoms caused by blood stagnation disappear. The Gorzdrav pharmacy provides the opportunity to buy the drug at an affordable price.

Cautions and possible body reactions

Almost any medicine has its contraindications and possible side effects. Therefore, before using the medicine "Phlebodia 600", you should consult with your doctor, who will prescribe the most effective treatment for the patient, taking into account all possible contraindications.

What contraindications does the drug have, the active component of which is Diosmin? Key warnings to consider before taking it include:

• childhood. This medication is not recommended for use before reaching 18 years of age;
• lactation period. The components included in the medicine can affect the child through mother's milk;

• first trimester of pregnancy. It is not recommended to take the pills before the 12th week of pregnancy;
• allergy to the components of the tablets. An individual negative reaction of the body to Diosmin or other components of the medication is a significant contraindication to taking this drug.

The instructions for the tablets also describe possible side effects associated with taking this drug: allergic reactions, gastrointestinal disorders, headaches. Side effects, provided that the dosage has not been exceeded and the rules for taking the drug are followed, occur quite rarely.

This medication does not provide negative impact when combined with other medications, however, before starting treatment, you should inform your doctor about all medications used. You can buy it, like any other medicine, at the Gorzdrav pharmacy.

Information for expectant mothers

Phlebodia 600 has no contraindications for the treatment of venous insufficiency in pregnant women after the end of the first trimester. Its safety has been confirmed clinical studies, as the abstract says. It is recommended to take one tablet per day, starting from the 2nd trimester of pregnancy. It is necessary to stop the course of drug therapy at least 14 days before the expected date of birth.

During pregnancy, the problem of varicose veins often arises. This is due to the fact that the load on the legs and pressure in the pelvic area increases, and the elasticity of the veins decreases due to hormonal changes. As a result, weakened veins in the legs expand and blood stagnates in them, causing swelling and pain.

In order for blood to circulate normally, it is necessary to maintain vascular tone; for this, vitamin supplements, such as “”, as well as, are prescribed.

“Phlebodia” is characterized by such important qualities during pregnancy as:

• safety;
• efficiency;
• ease of use (convenient form).

Received the drug positive reviews pregnant women who, with its help, got rid of unpleasant symptoms venous insufficiency during pregnancy. At correct use this medicine does not have a negative effect on the well-being of patients, including pregnant women. It can be purchased at the nearest Gorzdrav pharmacy. It is the Gorzdrav pharmacy that provides high-quality medicines at a competitive price.

Sometimes “Phlebodia” is compared with the drug “Ascorutin”, which according to its pharmacological group belongs to vitamins and vitamin-like drugs, since the action of both drugs is aimed at strengthening blood vessels, but this is not entirely correct. To find out why Ascorutin cannot be a replacement for Phlebodia 600, you should understand the features of its composition and functions.

"Ascorutin" is often used to prevent vein diseases, providing an antioxidant effect. Dosage form: film-coated tablets. Vitamins "Ascorutin" are aimed at strengthening the walls of capillaries and reducing their permeability. The composition of the vitamin product “Ascorutin” includes the following components:

• ascorbic acid, which thins the blood;
• rutin, which reduces capillary fragility.

These active components provide the beneficial effect of the drug "Ascorutin" on vascular system. "Ascorutin" involves prescribing as part of complex anti-varicose therapy for initial stages varicose veins or for its prevention. However, it is worth considering that Ascorutin is not a venotonic agent and can only be used as an addition to the main treatment. You can also purchase it at the Gorzdrav pharmacy.

Before taking Ascorutin medicinal purposes, you should consult your doctor, as it is necessary to take into account its interaction with other drugs.

Patients' opinions

Venotonic "Phlebodia" has positive reviews from both specialists and patients. Below are some reviews from people who are satisfied with the results of treatment with its use:

Catherine:“In the second half of pregnancy, I experienced great discomfort from pain in my legs and severe swelling, veins began to appear. The doctor prescribed me to drink Phlebodia, and I heard good reviews about these pills. I bought the drug at the Gorzdrav pharmacy. After about three weeks, a noticeable result appeared, my legs stopped hurting, and blue veins no longer appeared";

Tatiana:“Veins in my legs have been a long-standing problem of mine. Only after Phlebodia do I feel real improvement. I tried different tablets and ointments, but this drug really relieves unpleasant symptoms for a long time. There are similar tablets that cost a little less, but they take longer to use”;

Marina:“I was prescribed this drug after surgery. The bluish veins on my leg bothered me very much; surgery was impossible, after which the doctor advised me to take a course of medication 2 times a year. Looking at the photo after the problem veins were removed, I understand that no new ones appeared, and the unpleasant sensations disappeared. Now I regularly buy these tablets at the Gorzdrav pharmacy;

is a product of a French company that has firmly established itself in the Russian pharmacy market. An angioprotector drug to solve problems with varicose veins.

Phlebodia 600 - a remedy for varicose veins

Release form and composition of Phlebodia 600

The medicine Phlebodia 600 is available in tablets coated with a pink film coating. The package contains 1-2 blisters (15 tablets each).

One unit of the product contains 600 mg of the main active ingredient (diosmin) and a number of auxiliary components:

• stearic acid;
• colloidal silicon dioxide;
• microcrystalline cellulose;
• talc.

Packaging of Phlebodia 600 tablets

The drug is available in pharmacies without a prescription and remains usable for 3 years from the date of release. It must be stored in a place inaccessible to children at a temperature of no more than 30˚ C.

Price and analogues

Phlebodia 600 is a foreign product, which affects its cost. At the same time, there are several Russian analogues this product at a more reasonable price.

If necessary, Phlebodia 600 can be replaced by a cheap or equal Russian drug. The most obvious competitor to this drug is the inexpensive but effective Venozol.

Indications Phlebodia 600

Phlebodia is a concomitant medication and is used as one of the components of a complex therapeutic effect, allowing:

• eliminate lymphovenous insufficiency of the legs;
• restore impaired microcirculation;
• ensure the elimination of symptoms of hemorrhoids in the acute stage.

Phlebodia 600 is used to treat lymphovenous insufficiency of the legs

pharmachologic effect

Phlebodia 600 is one of the angioprotective agents, that is, it has a beneficial effect on the cardiovascular system.

This applies in particular to:

• reducing the distensibility of veins, toning them (the severity of the effect is determined by the dosage);
• preventing the occurrence stagnation in the veins;
• increasing the frequency of contraction of the capillaries of the lymphatic system
• increasing the tone and functional density of lymph vessels;
• lowering blood pressure;
• improvement of microcirculation;
• stimulating the process of blood supply to organs and replenishing insufficient intensive oxygen supply;
• relieving inflammation;
• inhibition of free radical production.

After entering the gastrointestinal tract, the drug is detected in the plasma after 2 hours, after which its concentration increases for another 3 hours. In this case, its uniform distribution and accumulation occurs in tissues and organs (mainly in the walls of the saphenous veins of the legs and vena cava).

The accumulation process is completed in approximately 9 hours, and the effect lasts approximately 3.5 days. A significant part of the drug (about 80%) is excreted through the kidneys.

Instructions for use Phlebodia 600

Use the product only after consultation with a specialist. It is intended for internal use.

For varicose veins of the legs and chronic manifestations of lymphovenous insufficiency (expressed in edema, pain syndromes and convulsions) the patient requires 1 tablet daily. He drinks it in the morning on an empty stomach. Full course treatment will last about 2 months.

If hemorrhoids worsen, the dosage regimen changes: you need to drink 2-3 tablets per day (one unit of medication with each meal). The duration of the therapeutic effect in this case is no more than a week.

In case of exacerbation of hemorrhoids, you need to take 2-3 tablets a day

Hemorrhoids should be treated using several medications at once. If such an effect does not bring the desired results, then it is necessary to undergo a specialized examination and adjust the therapy.

People with hypersensitivity require a break during the therapeutic course to relieve:

• heartburn;
• headache and stomach pain;
• feelings of nausea.

If any of the above phenomena worsens, you should immediately visit a specialist and get qualified help from him.

Contraindications and side effects.

Contraindications to the use of Phlebodia 600 include:

• excessive sensitivity to the components of the drug;
• lactation period;
• age less than 18 years;
• the first three months of pregnancy.

On early stages It is contraindicated to take Phlebodia 600 during pregnancy

When the drug was used by women during pregnancy in the second or third trimester, no side effects were observed. However, the drug can only be used as prescribed by a specialist, since this action poses a certain risk for the child.

No symptoms associated with overdose or concomitant use of the drug with other drugs were identified. There was also no effect of the drug on the ability to drive a car or other vehicle.

What's better?

The difference between medications of similar action and composition can be large.

To make an error-free choice, you have to answer a number of questions:

• what the drug contains in addition to the active substance;
• how to take the chosen medicine;
• what price will you have to pay for the medicine at the pharmacy.

The instructions that come with all of them help you understand this partly. medicines, but it's better to have accurate representation about how a certain remedy works.

Phlebopha or Phlebodia?

The speed of action of the drug Phlebofa is slightly higher than that of Phlebodia, since after 2 hours from the moment of administration its concentration in the blood already reaches its maximum. It also surpasses its French counterpart in price.

It should be taken several times a day before or after meals, with the maximum size daily dose cannot exceed 1800 mg.

Phlebofa is more expensive than Phlebodia 600

According to research results, it was revealed that, unlike Phlebodia, Phlebopha does not have a negative effect on the child that a woman is carrying, therefore this remedy can be taken safely during pregnancy.

Detralex or Phlebodia 600?

In general, the effect obtained from taking Detralex and Phlebodia 600 is very similar, so the priority of one of these drugs is determined by the individual needs of the patient.

The cost of these drugs, when purchasing a package of 30 tablets, differs little, so this parameter can not be taken into account when comparing.

Troxevasin and Phlebodia?

Troxevasin (in tablet form) is degraded primarily in the liver. Then, along with bile and urine, it is excreted from the body. Phlebodia puts a similar load on the kidneys. Therefore, here you need to decide which organ is healthier and able to withstand treatment with such drugs.

Troxevasin puts stress on the liver

Availability renal failure makes it impossible to take both medications. Also, Troxevasin is not suitable for people suffering from stomach and intestinal ulcers.

The only group of patients for whom the use of Troxevasin will definitely be preferable are allergy sufferers. In addition, it is prescribed not from the age of 18, but from the age of 15.