Acc for children must be diluted with hot water. Traditional and non-traditional methods of treatment. Side effects of ACC

Respiratory diseases have always occupied and continue to occupy a leading position among diseases in children. Their main pathogenetic feature is disruption of the ciliated epithelium, which leads to disruption of mucociliary clearance. This is mainly due to increased sputum production or its excessive viscosity.

What is mucociliary clearance and why is it needed?

Mucociliary clearance (MC) is a protective mechanism, without which the normal functioning of the respiratory system is impossible. MK also performs immune and cleansing functions. Along with bronchial secretions, foreign particles and microorganisms that can lead to serious illnesses. If the sputum is viscous, there is a decrease in mucus transport, which reduces local immunity.

These conditions subsequently lead to impaired breathing and gas exchange in the lungs.

When inflammation occurs in the respiratory system overeducation mucus and changes in its rheological properties. As a result, a cough appears, which is designed to clear the airways of excess secretions.

What is a cough?

Cough is a real protective mechanism for restoring the patency of the respiratory tract. But it is worth noting that a productive cough can only be with normal physiological rheological properties of sputum, that is, with good viscosity and quantity.

Due to this cleaning mechanism bronchial tree medications are used that have a direct effect on the secretion. These drugs are usually called bronchosecretolytics, or mucolytics.

Cough medicines

On this moment Secretomotor drugs based on the herbs thermopsis, marshmallow, and potassium iodide are used less and less. These trends are due to the fact that these drugs have many side effects and do not always have a beneficial effect on general state organism.

Mucolytics

Mucolytic drugs are used quite widely for acute respiratory infections. infectious diseases, such as bronchitis, tracheitis, pneumonia, as well as chronic diseases respiratory system(bronchial asthma (BA), chronic obstructive pulmonary disease (COPD), hereditary and congenital diseases bronchopulmonary tract).

Mucolytics are divided into 3 groups:

Ambroxol derivatives;
Acetylcysteine preparations ( ACC effervescent pills, powders, granules);
Carbocisteine preparations.

To date, proteolytic enzymes are not used as mucolytics, because they can damage lung tissue and the walls of the bronchi, which can lead to severe complications in the form of bronchospasm, allergic reactions.

Preparations of the acetylcysteine group

Medicines from this group are now quite popular and well-known representative is ACC. The acetylcysteine molecule is unique because it has a very fast and lasting effect. This effect is achieved by acting directly on sputum.

Effects of acetylcysteine

Acetylcysteine contains in its structure sulfhydryl reactive groups that can break the disulfide bonds of sputum, which leads to its dilution and better elimination when coughing. In this case, the effect of secretion of sialomucins by goblet cells of the mucous membrane occurs, which disrupts the attachment of bacteria to the latter. An increase in mucus secretion promotes the dissolution of fibrin, which is deposited on the surface of the ciliated epithelium of the bronchial mucosa. The activity of the drug applies to any type of sputum, be it purulent sputum or serous-mucous.

How to take ACC?

For adults and adolescents over 14 years of age, acetylcysteine is prescribed in a dosage of 400-600 mg per day. The dose is divided into 2-3 doses.

A fairly wide variety of release forms is available in ACC drug. It is designed to be taken orally 2-3 times a day. It is produced in the form of tablets, powders of 100 and 200 mg, and in the form of extended-release tablets of 600 mg for once a day. Granules are also available in a dosage of 600 mg for preparing a solution.

Pharmacokinetics

ACC begins to act within half an hour after taking the drug. It lasts for 4 hours. After ingestion, acetylcysteine is completely absorbed by the gastric and intestinal mucosa. However, the bioavailability of the substance is quite low due to its passage through the liver. Here the formation of active metabolites of cysteine, diacetylcysteine and cystine occurs, which have their positive effect.

Acetylcysteine binds to blood plasma by 50%. After 1-3 hours the maximum concentration is reached active substance in blood.

Pharmacodynamics

Acetylcysteine is excreted from the body through urine. Mostly inactive metabolites are excreted. Typically the entire process takes about 8 hours due to hepatic biotransformation.

Side effects

Sometimes acetylcysteine can excessively thin the sputum, thereby causing the effect of flooding the lung. This condition often develops with impaired urinary function and a weak cough. In young children, suction may be used to remove excess mucus from the airways. Large doses ACC for cough may cause a decrease in prothrombin time.

Interactions with other drugs

Acetylcysteine is never prescribed together with antitussive drugs. Such an appointment can lead to stagnation of sputum and the development of complications. Acetylcysteine enhances the effect of nitroglycerin when used together, so you need to remember this effect.

ACC has the ability to reduce the absorption of cephalosporins, tetracyclines, and penicillins. It is for this reason that it is recommended to take these medications 2 hours after taking ACC.

Contraindications

It is not advisable to use ACC for hemoptysis.

Antioxidant effect of acetylcysteine

The SH group in the drug is capable of neutralizing free radicals(SR). The antioxidant effect of ACC is manifested even when prescribed in small dosages. This effect occurs not only at the biochemical, but also at the biological level.

Diseases of the respiratory tract are always accompanied by increased oxidative reactions, as a result of which an excessive amount of SR is formed, affecting the tissues and cells of the body in an unfavorable negative way, forming oxidative stress. Oxidative stress additionally damages the bronchial walls and mucous membranes. The drug has a protective effect on cells and does not allow SR to exert its destructive impact. Due to the provision this effect ACC also has an anti-inflammatory effect.

Examples of the use of acetylcysteine as an antidote

In addition, the drug also has a detoxifying effect and can be taken for poisoning with paracetamol, aldehydes, and phenols. In 1990, D. Mattin described the case of a 32-year-old patient who was poisoned large dose arsenic. The administration of demercaprol and other detoxification measures were ineffective. The patient's condition worsened every hour. After 27 hours of unsuccessful fight against poisoning, ACC was introduced. Within 24 hours the patient began to recover, and a few more days later he was discharged in satisfactory condition.

In this article you can find instructions for use medicinal product ACC. Reviews of site visitors - consumers of this medicine, as well as opinions of specialist doctors are presented. using ACC in your practice. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogs of ACC, if available structural analogues. Use for the treatment of bronchitis and dry cough in adults, children, as well as during pregnancy and lactation. Various forms of release of the drug for thinning sputum.

ACC- mucolytic drug. The presence of sulfhydryl groups in the structure of the acetylcysteine molecule promotes the rupture of disulfide bonds of acidic mucopolysaccharides of sputum, which leads to a decrease in the viscosity of mucus. The drug remains active in the presence of purulent sputum.

With the prophylactic use of acetylcysteine, there is a decrease in the frequency and severity of exacerbations in patients with chronic bronchitis and cystic fibrosis.

Compound

Acetylcysteine + excipients.

Indications

respiratory diseases accompanied by increased formation of viscous mucus that is difficult to separate (acute and chronic bronchitis, obstructive bronchitis, pneumonia, bronchiectasis, bronchial asthma, bronchiolitis, cystic fibrosis, laryngitis);
acute and chronic sinusitis;
otitis media.

Release forms

Powder or granules for making syrup 100 mg.

Syrup 100 ml.

Effervescent tablets 100 mg, 200 mg, 600 mg long.

Solution for injection ACC injection - 100 mg and 300 mg in 1 ml.

Instructions for use and dosage

Powder or effervescent tablets

Adults and adolescents over 14 years of age are recommended to prescribe the drug 200 mg 2-3 times a day (ACC in the form of granules for the preparation of an oral solution / orange / 100 mg and 200 mg), or 200 mg 3 (ACC in the form of granules for preparing a solution for oral administration 200 mg) or 600 mg 1 time per day (ACC in the form of granules for preparing an oral solution 600 mg).

Children aged 6 to 14 years are recommended to take 100 mg 3 times a day or 200 mg 2 times a day (ACC in the form of granules for oral solution / orange / 100 mg and 200 mg), or 200 mg 2 times a day (ACC in the form of granules for the preparation of a solution for oral administration 200 mg).

There is not enough data on the dosage of the drug in newborns.

For cystic fibrosis, children over 6 years of age are recommended to take the drug 200 mg 3 times a day (ACC in the form of granules for preparing an oral solution /orange/ 100 mg and 200 mg or ACC in the form of granules for preparing an oral solution 200 mg ).

Children aged 2 to 5 years - 100 mg 4 times a day (ACC in the form of granules for the preparation of an oral solution / orange / 100 mg and 200 mg).

For patients weighing more than 30 kg with cystic fibrosis, if necessary, the dose can be increased to 800 mg per day.

For sudden short-term colds, the duration of use is 5-7 days. At chronic bronchitis and cystic fibrosis, the drug should be used for a longer period of time to prevent infections.

The drug should be taken after meals. Additional fluid intake enhances the mucolytic effect of the drug.

Rules for preparing the drug

ACC in the form of granules for the preparation of a solution for oral administration /orange/ 100 mg and 200 mg: 1/2 or 1 sachet (depending on the dose) dissolved in water, juice or iced tea and taken after meals.

ACC in the form of granules for the preparation of a solution for oral administration 200 mg and ACC in the form of granules for the preparation of a solution for oral administration 600 mg: 1 sachet is dissolved with stirring in 1 glass hot water and drink it hot if possible. If necessary, you can leave the prepared solution for 3 hours.

Syrup

Adults and adolescents over 14 years of age are prescribed 10 ml of syrup 2-3 times a day (400-600 mg of acetylcysteine).

Children aged 6 to 14 years - 5 ml of syrup 3 times a day or 10 ml of syrup 2 times a day (300-400 mg of acetylcysteine).

Children aged 2 to 5 years are prescribed 5 ml of syrup 2-3 times a day (200-300 mg of acetylcysteine).

For cystic fibrosis, children over 6 years of age are recommended to take the drug 10 ml of syrup 3 times a day (600 mg of acetylcysteine); children aged 2 to 6 years - 5 ml of syrup 4 times a day (400 mg of acetylcysteine).

For short-term colds, the duration of use is 4-5 days. For chronic bronchitis and cystic fibrosis, the drug should be used for a longer period of time to prevent infections. For long-term illnesses, the duration of therapy is determined by the attending physician.

The drug is taken orally after meals. Additional fluid intake enhances the mucolytic effect of the drug.

ACC syrup is taken using a measuring syringe or measuring cup contained in the package. 10 ml of ACC syrup corresponds to 1/2 measuring cup or 2 filled syringes.

Using a measuring syringe

1. Open the bottle cap by pressing on it and turning it counterclockwise.

2. Remove the cap with the hole from the syringe, insert it into the neck of the bottle and press in until it stops. The stopper is designed to connect the syringe to the bottle and remains in the neck of the bottle.

3. It is necessary to insert the syringe tightly into the stopper. Carefully turn the bottle upside down, pull the syringe plunger down and draw required amount syrup (ml). If air bubbles are visible in the syrup, press the plunger all the way and then refill the syringe. Then return the bottle to its original position and remove the syringe.

4. The syrup from the syringe should be poured onto a spoon or directly into the child’s mouth (into the cheek area, slowly, so that the child can swallow the syrup). While taking the syrup, the child should be in an upright position.

5. After use, rinse the syringe with clean water.

Ampoules for injections

Adults are prescribed intravenously or intramuscularly at 300 mg (1 ampoule) 1-2 times a day.

Children aged 6 to 14 years are prescribed IV or IM 150 mg (1/2 ampoule) 1-2 times a day.

For children under 6 years of age, oral therapy is preferred, however, if indicated and parenteral administration is necessary, the daily dose is 10 mg/kg body weight.

For children under 1 year of age, intravenous administration of the drug is possible only for health reasons in a hospital setting.

The duration of therapy is determined individually.

In case of chronic bronchitis and cystic fibrosis, the use of ACC INJECT for a long time can be combined with oral administration of the drug to prevent infections.

The mucolytic effect of acetylcysteine increases with increased fluid intake.

Rules for injections

With intramuscular injection when performing a shallow injection and in the presence of hypersensitivity A slight and quickly passing burning sensation may occur, so it is recommended to administer the drug to patients in a lying position and deep into the muscle.

For intravenous administration, the first dose must be diluted with 0.9% sodium chloride solution or 5% dextrose solution in a 1:1 ratio. The drug should, if possible, be administered by infusion.

IV injections should be administered slowly (over 5 minutes).

Side effect

headache;
noise in ears;
stomatitis;
diarrhea;
vomit;
heartburn;
nausea;
drop in blood pressure;
tachycardia;
development of pulmonary hemorrhage as a manifestation of a hypersensitivity reaction;
bronchospasm (mainly in patients with a hyperreactive bronchial system with bronchial asthma);
skin rash;
hives.

Contraindications

peptic ulcer and duodenum in the acute phase;
hemoptysis;
pulmonary hemorrhage;
pregnancy;
lactation period (breastfeeding);
children under 2 years of age (the drug is in the form of granules for the preparation of a solution for oral administration /orange/ 100 mg and 200 mg, syrup and ACC 200);
children under 6 years of age (the drug is in the form of granules for the preparation of a solution for oral administration, 200 mg);
children under 14 years of age (the drug in the form of granules for the preparation of a solution for oral administration 600 mg and ACC Long);
hypersensitivity to acetylcysteine and other components of the drug.

Use during pregnancy and breastfeeding

Due to insufficient data, the use of the drug during pregnancy is contraindicated.

For syrup: use of the drug during pregnancy is possible only if the expected benefit to the mother outweighs the potential risk to the fetus.

If it is necessary to use the drug during lactation, the issue of stopping breastfeeding should be decided.

Use in children

Contraindicated for children under 2 years of age (the drug in the form of granules for the preparation of an oral solution /orange/ 100 mg and 200 mg, syrup and ACC 200), up to 6 years of age (the drug in the form of granules for the preparation of an oral solution 200 mg) , up to 14 years (the drug in the form of granules for the preparation of a solution for oral administration 600 mg and ACC Long).

special instructions

For bronchial asthma and obstructive bronchitis acetylcysteine should be prescribed with caution under systematic monitoring of bronchial patency.

Severe allergic reactions such as Stevens-Johnson syndrome and Lyell's syndrome have been very rarely reported with the use of acetylcysteine. If changes in the skin and mucous membranes occur, the patient should immediately stop taking the drug and consult a doctor.

When dissolving the drug, it is necessary to use glass containers and avoid contact with metals, rubber, oxygen, and easily oxidized substances.

You should not take the drug immediately before bedtime (the preferred time of administration is before 18.00).

During development side effects the drug should be discontinued.

ACC (in the form of granules for the preparation of solution for oral administration / orange / 100 mg and 200 mg) 100 mg corresponds to 0.24 XE, 200 mg - 0.23 XE.

Impact on the ability to drive vehicles and operate machinery

Information about the effect of the drug on the ability to drive vehicles and potentially engage with others dangerous species activities requiring increased concentration attention and speed of psychomotor reactions are absent.

Drug interactions

At simultaneous use acetylcysteine and antitussives may cause dangerous mucus stagnation due to suppression of the cough reflex (use the combination with caution).

When taking ACC with vasodilators and nitroglycerin simultaneously, the vasodilator effect may be enhanced.

There is a synergism between acetylcysteine and bronchodilators.

ACC is pharmaceutically incompatible with antibiotics (penicillins, cephalosporins, erythromycin, tetracycline and amphotericin B) and proteolytic enzymes.

Acetylcysteine reduces the absorption of cephalosporins, penicillins and tetracycline, so they should be taken orally no earlier than 2 hours after taking acetylcysteine.

Upon contact of acetylcysteine with metals, rubber, sulfides are formed with a characteristic odor.

Analogues of the drug ACC

Structural analogues of the active substance:

N-AC-ratiopharm;
N-acetylcysteine;
Acestine;
Acetylcysteine;
Acetylcysteine SEDICO;
Acetylcysteine solution for inhalation 20%;
Acetylcysteine solution for injection 10%;
Mukobene;
Mucomist;
Mukonex;
N-AC-ratiopharm;
Fluimucil;
Exomyuk 200.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.

Let's talk about an effective tool that is gaining more and more popularity among specialists and patients - acc.

Features of the composition

The drug is available in the following dosages: one hundred, two hundred and six hundred milligrams. ACC Long has a longer duration of action - 12 hours; it can be taken no more than twice a day.

Effervescent tablets are easy to use and are therefore the most popular form

The drug is available in the following forms:

effervescent pills;
inhalation mixtures;
granules for making syrup;
solution for injection.

The main component of ACC is acetylcysteine, which is a derivative of cysteine.

Each form of the drug is distinguished by the presence of various auxiliary components. Let's talk in more detail about each form.

Syrup

The drug contains the following additional components:

carmellose sodium;
cherry flavor;
sodium benzoate;
sodium hydroxide.

Tablet form

ACC tablets contain the following components:

Powder

The powder used to obtain medicinal solution, includes the following components:

ACC provides beneficial effect on the mucous membrane of the respiratory tract, and also helps remove mucus from the lungs in a short time

You need to take it along with drinking plenty of fluids, which will speed up the effect.

Indications for use

The drug is prescribed for the following diseases:

What is the secret of the drug?

The tablets have the following unique properties:

mucolytic property. If you say in simple words, the use of the drug leads to a change in the consistency of sputum. Essentially changing chemical structure sputum. It increases in volume and liquefies, which in turn leads to its easier detachment from the walls of the bronchi and better expectoration. Local restoration of protection of the entire respiratory system also occurs. The accumulation of sputum causes a cough, so when it is separated, the cough goes away. The drug effectively fights sputum of both mucous and purulent nature;
antioxidant and detoxifying abilities. Experimentally It has been proven that in acute respiratory viral diseases, taking ACC helps alleviate clinical symptoms;
enhancing the effect of antibacterial therapy. Thanks to the medicine, antibiotics better penetrate the bronchial mucosa.

The drug begins to act within one hour

Effect

Within an hour or even half an hour, the tablets begin to act. The effect lasts for four hours, if it is a prolonged form of the drug, then the result will last for a day.

Already from the first day, the tablets will show their results, and if they are taken for three days, the maximum effect will be achieved.

Cautions

In what cases should the drug not be used? It is contraindicated to drink the drug in the following cases:

pulmonary hemorrhage;
pregnancy and lactation;
renal failure;
peptic ulcer;
hepatitis;
hypersensitivity to any component of the drug.

Cough treatment with acc should not be carried out without prior advice from a doctor.

The body of each person is individual, so the following side effects may occur:

headache;
noise in ears;
nausea, vomiting;
stomatitis;
heartburn;
tachycardia;
allergic reactions in the form of rash and itching;
hypotension.

Admission rules

Each type of drug has its own daily dose.

Is it possible to give medicine to treat cough in children? From birth, doctors prescribe ACC with a dosage of one hundred milligrams. If we talk about a prolonged drug, then it can be used from the age of 14.

The dosage prescribed by the specialist must be strictly observed.

The tablet should be dissolved in warm water and drunk after meals. If you forget to drink the drug, then the solution should not be consumed after two hours.

The powder from which the solution is made can be added not only to water, but also to tea, juice or compote.

Analogues

There are cheap analogues this tool. These include the following popular analogues:

Cough in children

Children's ACC comes in three forms: effervescent tablets and granules for syrup, as well as solution. In the course of twenty clinical trials the safety of the main component for the treatment of children has been proven.

Don't hope that cough will go away yourself, immediately contact your pediatrician

Thanks to the convenient dosage, as well as good taste the drug has found its niche in the treatment of childhood diseases.

Overdose

Overdose occurs in the following cases:

if you use adult forms for children;
exceeding the average therapeutic dosage;
accumulation of a medicinal substance in the body;
long-term use;
metabolic disorder in the liver.

special instructions

As mentioned earlier, the period of pregnancy and lactation is a contraindication for use; however, during this period the drug can be used under medical supervision.

You should not take the medicine together with antitussive drugs that suppress the cough reflex.

Reviews

Victoria, 30 years old: “My daughter fell ill with the flu, which was complicated by the development acute bronchitis. I didn't know what to do with my wet cough. We contacted family doctor, who recommended the remedy ACC. Before that, I had only heard about this remedy, but had never tried it.”

Reviews from patients suffering from dry cough undoubtedly indicate the effectiveness of the ass.

Anna, 35 years old: “I give my children only proven drugs, so before buying the medicine, I started researching the instructions, which pleasantly surprised me. Having decided to buy the product, we began to use it. I was so glad when I saw the result and the relieved condition of my child.”

Galina, 25 years old: “I fell ill with tracheitis, which was accompanied by a strong dry cough. My friend tried ACC on herself and zealously recommended it to me too. I decided to buy effervescent pills that tasted like lemonade. I dissolved one tablet in a glass warm water and took it throughout with an expectorant. To my joy, the cough went away.”

Georgiy, 40 years old: “I developed a dry cough, which bothered me because I work with people. I don’t like to be treated, and if I do take medications, it’s those that quickly have an effect. Acc helped a friend, so I decided to try it. The next day the cough did not completely go away, but it became much milder. This prompted me not to stop and take the product further, after just three days unpleasant symptom passed.”

So acc is effective remedy in the treatment of cough in both children and adults. Ask your doctor about this drug and see for yourself how effective it is!

Comments

We take it for dry cough, bronchitis and other infections with cough. It helps very well to thin out mucus if the cough is dry, and it begins to subside on the second day of use. And the Long form is just a fairy tale. How much water should 200g of powder be dissolved in? Natalya’s child doesn’t finish her dose, but what is it?

Drink acc long It's been five days already. The cough doesn't go away. Here's a Gerbion saw - super. I think I'll go buy it tomorrow.

I’ve been taking it for three days now along with Lazolvan. A wet cough has turned into a dry one, not coughing at all.

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ATTENTION! All information on the site is for informational purposes only and does not claim absolute accuracy. medical point vision. Treatment must be carried out by a qualified doctor. By self-medicating, you can harm yourself!

How to use ACC for cough

The drug "ACC" (in Russian, more often called ACC), is prescribed for coughs in the treatment of colds various types. In addition, the drug is prescribed in the presence of allergic cough spasms; it has several release forms and dosage options, the choice of which depends on the age and weight of the patient. “ACC Long” has the longest duration of action, the effect of which lasts for 12 hours. The latest variation of the drug is taken only twice a day.

For which cough should I take Acc, dry or wet?

Cough spasms can be either productive, in which sputum is produced, or dry, most often manifested in the initial stage colds. Initially, the drug is positioned by manufacturers as a remedy for wet cough, which helps remove mucus from the respiratory system and makes breathing easier. However, “ACC” also helps with dry cough, bringing it to the productive stage.

IN medical practice it is customary to prescribe this medicine V various forms for the following ailments:

pneumonia;
different types of bronchitis, in particular obstructive, chronic and acute;
bronchiectasis;
sinusitis of various nature;
otitis, against the background of which a cough spasm occurs;
broncholitis;
laryngotracheitis;
muvoviscidosis.

It is worth considering that clinical benefit from this drug is only possible if it is used to treat ailments included in the list of those listed above. Thus, you should not try to stop a cough spasm with the help of “ACC” on your own. If the drug does not give any effect, then, most likely, the disease does not belong to its action profile.

How does the medicine work?

The drug "ACC" is considered an excellent way to combat sputum that occurs in the cavity of the respiratory tract, lungs and bronchi due to various kinds infectious lesions. Sputum while trying to natural causes come out, provokes a cough, and often this substance turns out to be too viscous and dense, which leads to too strong adhesion to the bronchi. With the help of "ACC" it is possible not only to completely establish, but also to advance the process of sputum discharge from the respiratory organs and its removal to the outside.

The main component of the drug is a cysteine derivative; this amino acid directly affects the structure of sputum, changing its consistency. The mucus increases in its condition, easily detaches from the bronchi and is naturally removed from the respiratory tract. Due to the removal of sputum, the healing process occurs, and the protective reactions of the mucous membranes are restored.

It is noteworthy that the action of “ACC” is aimed at eliminating not only ordinary mucous sputum, but also that which has already appeared purulent formations. The drug is often used in combination with antibacterial drugs, since it facilitates the penetration of the latter into the mucous part of the respiratory organs. It is important to maintain a two-hour interval between medications. Besides active action for sputum, cough medicine has antioxidant properties; accordingly, acetylcysteine significantly facilitates the course of any viral infection.

In fact, the drug eliminates the symptoms characteristic of severe flu, while simultaneously fighting cough spasms.

Instructions for use of tablets and powder ACC (acc) for dry cough

The correct dosage of the drug is calculated based on the type of disease for which therapy is being carried out, the age and weight of the patient. In addition, the dosages of “ACC” for dry cough are different for children and adults. When treating such a serious illness as cystic fibrosis, the daily dose of the drug is no more than 800 mg, provided that the patient’s weight exceeds 30 kg. The duration of therapy can be very long and last at least 3-6 months. Treatment should be carried out only under the supervision of a doctor and taking into account the use of a complex of drugs.

For the treatment of dry cough spasm in other respiratory diseases for people over 14 years of age, a dosage of 400 to 600 mg of the drug in the form of tablets or powder consistency is indicated at one time. If there is too much acute course illness, then taking medications under the supervision of a doctor lasts at least a week. For a chronic illness, a dry cough can be treated with tablets or ACC powder for about six months.

According to the instructions for use, unless otherwise prescribed by a doctor, the drug is taken immediately after meals as an expectorant. The method of taking the medicine is as follows: the powder or a certain number of tablets are dissolved in ½ glass of water or tea and drunk immediately.

Medicines for children are taken according to a different scheme, and here important point is the type of drug relative to the dosage of the active component in it:

"ACC 100" is approved from birth for the treatment of dry cough in infants. The dosage for children under 2 years of age is 50 mg three times a day, then the dosage is increased to 100 mg in four doses, and after six years this medication should be taken at a dosage of 600 mg per day, which should be divided into three doses.
"ACC 200" is permitted only for children over 6 years of age, and the use of the medicine is permitted only in the form of a solution. Do not use more than two sachets of powder dissolved in water at any one time. For adolescents aged 14 years and over, the number of sachets is increased to three, which is equal to the adult dosage.
"ACC Long" is allowed only after 14 years of age, daily dosage of this type of drug should not exceed 600 mg, and the patient must receive it in one dose. The tablet dissolves in water and is taken orally immediately after meals. The duration of storage of the solution does not exceed half an hour, in otherwise the tablet must be re-dissolved for a new solution.

Children's cough syrup Ass

To treat cough in children, manufacturers produce a special form of the drug “ACC” in the form of a syrup, the administration and tolerability of which is much easier than a solution obtained from tablets or powder. The medicine in this form is convenient because it is ready for use and does not require additional actions on breeding.

The syrup dosage is calculated using a measuring cup, and it depends on the age and, accordingly, the weight of the child. In particular, 5 ml of the drug is equal to one quarter of a glass.

If the child’s age ranges from 2 to 6 years, then 5 ml should be taken no more than three times a day. After 7 years, the number of doses increases to 3-4, or it is permissible to take 10 ml at a time, but twice a day. After 15 years, the daily dose is 10 ml 3 times a day. The drug also contains a special syringe for easy dosage calculation. Its use is very convenient for treating very young children.

Contraindications and side effects

Like any medicine, ACC for cough has its contraindications, non-compliance with which can lead to side effects. According to the instructions developed by the manufacturers of the medicine, it is prohibited for use in the following cases:

coughing up bloody mucus;
bleeding in the lungs;
fructose intolerance at the genetic level;
individual intolerance to the main component of the medication and other substances in its composition;
renal failure, various liver diseases, especially hepatitis;
the presence of a peptic ulcer.

As side effects when taking this drug It is customary to consider such phenomena as various allergic reactions, rapid heartbeat, heartburn, general disruption of the gastrointestinal tract, which manifests itself in the form of diarrhea and vomiting, headaches and tinnitus.

Allergic reactions are typical in the presence of individual intolerance to substances in the drug; in this case, immediate discontinuation of the drug is required due to the risk of angioedema. In other cases, the study did not identify any situations in which taking it would pose a risk. human life. If any signs of side effects appear, you should immediately stop taking the drug and consult a doctor to adjust the treatment regimen.

The drug "ACC" is successfully used to treat various ailments, accompanied by dry and productive cough. The drug and its dosage should be prescribed only by a doctor after diagnosis.

During seasonal colds, children also often get sick. A common symptom is a cough, either dry or wet. It affects schoolchildren, adult children, as well as very young children, infants or those who have just started kindergarten.

A painful cough first irritates the throat, it is dry and rough, like a bark. A nonproductive cough gives way to an obstructive one, and sputum begins to be produced.

The soreness and pain in the chest disappear, wheezing and gurgling appear, and the child tries to cough up the mucus in the throat. Then the time has come to take the ACC drug, but it is important to know about the side effects.

ACC is a mucolytic, that is, a medicine that removes sputum. In addition, the drug has expectorant properties. In addition, it reduces inflammation and removes toxins. The main active ingredient here is acetylcysteine, and the drug is produced in Germany and Slovenia.

The instructions for use of ACC describe in detail the action of the product. It says there active ingredients destroy chemical bonds in the molecules of a viscous liquid, crushing them into small particles.

The mucolytic destroys mucopolysaccharide, sulfhydryl, mucoprotein bonds in sputum, and also depolymerizes them. In addition, the drug binds and neutralizes free radicals and fights bronchial inflammation.

In addition to effectively removing sputum, the product activates the formation and secretion of bronchial secretions. It destroys the purulent mucus of the sputum substance in the nasopharynx, paranasal sinuses, eustachian tube, as a result of which inflammation is neutralized, toxins and other harmful substances. Thanks to it, the ciliary activity of the epithelium of the bronchopulmonary system increases significantly.

The mechanism of action of acetylcysteine on the bronchial glands and alveolar cells leads to the dilution of sputum and its more intensive removal from the respiratory tract. As a result, cough of any origin gradually goes away.

The more intensely a person coughs, the faster the disease will recede.

Indications

There are many types of cough, and it changes every few days. For two weeks colds A dry cough and a wet, barking, paroxysmal, short single cough from an obsessive sore throat may appear.

A doctor will be able to accurately determine the type, cause and characteristics of a child’s cough during a personal examination. After listening to the patient, he must question him in detail, find out when the cough began, under what circumstances, whether there are any accompanying phenomena, in particular, temperature, what exactly is bothering the child.

Formation of thick and viscous mucus in the lungs

It usually appears first barking cough, it is dry, heavy, sometimes tearing at the throat. Often the child wheezes and loses his voice. After 3 or 5 days, the cough takes a productive form, that is, sputum begins to separate. Pain and soreness in chest pass, coughing up mucus begins.

If a doctor listens to a patient and detects wheezing in the lungs, similar to the collapse of large and medium-sized bubbles, as well as heavy, extended exhalations, harsh breathing, this indicates the formation of thick and viscous sputum in the lungs. Then it is necessary to prescribe a drug based on acetylcysteine.

ACC is prescribed to a patient if one of several diagnoses has been made:

Pneumonia.
Exacerbation bronchial asthma.
Laryngitis, tracheitis.
Bronchiolitis.
Bronchitis, simple or obstructive.
Cystic fibrosis of the lung.
Otitis.
Sinusitis.
Paracetamol poisoning.
Postoperative prophylaxis to avoid respiratory complications.

The drug is prescribed for diseases of the respiratory tract with the release of thick sputum. As a rule, all these diseases are in the acute stage.

Contraindications and side effects of the drug

Side effects when children take ACC, there are different types:

skin itching;
nausea;
vomit;
diarrhea;
headache;
bronchial spasms;
heartburn;
noise in ears;
inflammation of the mucous membranes of the mouth and pharynx;
tachycardia.

For newborns, the restrictions are very strict due to their inability to cough normally.

The doctor will prescribe ACC for the baby only if there is a vital need. In this case, both parents and the doctor need to monitor him very carefully so that the child does not choke.

As for contraindications, the medicine should not be given to children who meet at least one of the following factors:

duodenal ulcer or stomach ulcer, currently exacerbated;
bronchial asthma;
tendency to pulmonary bleeding;
hypersensitivity to constituent components medicines;
coughing up blood;
disease of the adrenal glands, liver, kidneys.

It is forbidden to start taking ACC during antibiotic therapy. The antibiotic may cause undesirable consequences, which will have to be eliminated with symptomatic therapy. The drug also enhances the effect of bronchodilators.

Due to the mucolytic activity of the drug simultaneous administration antitussives and the use of such devices is impossible due to the mutual opposition of these groups of drugs.

Nothing should interfere with the passing sputum, so it is dangerous to suppress cough reflexes during treatment. In addition to all this, it is important to remember that it is necessary to closely monitor children who do not yet know how to cough on their own.

It turns out that ACC should not be given to children with damage to the lungs, digestive and excretory systems. The drug is incompatible with antibiotics and antitussive medications. Give to infants with caution.

Manufacturers made sure that different situations and a certain form of the drug is suitable for different children. Therefore, ACCs are produced in several different variations:

Powder (granules) – for preparing a hot drink. You need to drink it without waiting for it to cool down. Can be used as a base plain water, and tea, juice, herbal decoction. If you plan to drink the prepared liquid gradually, deadline storage should not exceed 3 hours. It is better to take ACC after meals, it is advisable to drink more liquid. For children from 2 to 6 years old, take 1 sachet of powder twice a day; at the age of 7–14 years, the same dose is suitable, only 4 times a day; you can change to the option of taking the drug twice a day, two sachets at a time. Teenagers over 14 years old will have to drink up to 6 packets per day.
Syrup is finished form medication, accompanied by a dosage syringe or measuring cup. It is necessary to calculate the dose of syrup, taking into account that the capacity of the syringe is 5 mg, which is equal to 100 ml. If you measure it with a glass, then this dose will take up a quarter of its volume.
Effervescent tablets are a convenient form of medication in a compact package (tube). The tablet dissolves quickly in water at room temperature; you can warm it up a little. But be sure to drink the solution right away. At one time, children 2-6 years old take one tablet 2-3 times a day, children over 6 but under 14 - four times a day, adult teenagers can take the medicine up to 6 times.
Injections are used extremely rarely, especially for children. Exception - severe conditions, the patient is in the hospital. The solution is further diluted with dextrose (5%) or sodium chloride (0.9%) in equal proportions. For every kilogram of a child’s weight, 10 mg of medication is required. As a rule, such therapy does not last longer than 10 days.

The drug has 4 convenient forms and is dosed according to the instructions. Some options have special aids dosing.

Rules for receiving ACC, existing analogues

To therapeutic effect did not keep you waiting, and there were no side effects, you need to strictly follow general rules, which are suitable for all forms of the drug:

When preparing the next dose of the medicine, you are allowed to use only glass containers. Metal and rubber containers are not suitable for these purposes.
It is not recommended to take ACC before bedtime. It is best that the last dose is taken at 6 pm.
It is important to drink a lot of water. Excess fluid will help remove mucus faster and make it easier to expectorate.
Acute forms of respiratory tract diseases are treated for about a week, but if necessary, the pediatrician will extend the course to 10 days.
For asthmatics during therapy with acetylcysteine it is indicated constant control bronchial conduction, since there is a high probability of adverse reactions.
Children, sick diabetes mellitus, should include ACC in their insulin treatment plan. The instructions for the drug contain all the detailed data for diabetics.

The price of ACC in Russian pharmacies varies depending on the form of release:

effervescent tablets - 130-220 rubles;
granules – 150–200 rubles;
syrup – 250–300 rubles.

After the prices are announced, the question naturally arises: do ACCs have analogues, preferably cheaper ones? There are several such tools:

Fluimucil - injection solution will cost 120 rubles. per package, and effervescent tablets cost about 170 rubles.
Abrol is a syrup based on ambroxol, also available in tablets. The price varies between 100–150 rubles.
Mukosol - carbocisteine in syrup, costs 150–200 rubles.
- most cheap analogue, available in lozenges, costs about 30 rubles. Made from marshmallow.
Bromhexine is an inexpensive syrup from Latvia priced at 125 rubles. per bottle.
Gedelix - available in syrup, active substance– ivy extract. Cost in pharmacies is 350 rubles.

Having such an excellent alternative, you can seriously save money, and the variety of release forms will make any medication convenient.

Video about children's cough medicines:

ACC for dry cough is traditionally prescribed by doctors because the active substance acetylcysteine has a mucolytic effect.

Pharmaceutical companies manufacture various dosage forms so that a patient of any age can use this medicine to transform a non-productive cough into a productive form.

When discussing whether it is possible to drink ACC for a dry cough, you need to know that this active substance changes the structure of the viscous secretion. It normalizes the content of protein, immunoglobulins, glycoproteins, enzymes in sputum, suppresses the growth of microorganisms, reducing the percentage of their waste products. This effect of acetylcysteine allows you to change the characteristics of cough and relieve inflammatory process occurring in the respiratory system.

Why does the medicine help?

ACC is recommended for the treatment of dry cough by therapists and pediatricians who know exactly whether or not this active substance can be used for diseases of the respiratory system. Acetylcysteine is a substance that began to be actively used to treat cough at the beginning of the 21st century. It is a derivative derived from the amino acid cysteine, which is found in many foods containing proteins. Cysteine is involved in processes responsible for tissue formation and detoxification of the body. The presence of this amino acid in the body allows the destruction of mucus in respiratory tract. It accelerates the healing processes of the respiratory system, activating the production of leukocytes and lymphocytes.

If a person takes a single dose of ACC for any cough, dry or wet, he will feel relief after the active substance is absorbed in the intestines into the plasma and reaches the liver. The necessary metabolic changes occur there, converting acetylcysteine into the amino acid cysteine, and it naturally enters into various biochemical reactions leading to sputum production.

The amino acid quickly breaks down, and its remains are excreted from the body through excretory system 3 hours after taking the medicine.

This ability of the active substance to be quickly eliminated from the body makes it possible to answer positively the question of parents about whether ACC can be used for children with a dry cough. Doctors often recommend it to children over 2 years of age when other medications for dry cough do not help get rid of it.

When does the drug help?

A preparation using an amino acid involved in natural metabolic processes, brings significant benefits to a weakened body. This explains why manufacturers recommend taking ACC for dry or wet cough if sputum is difficult to separate and chest pain occurs.

On a note! The medicine works effectively for any respiratory diseases. The active substance allows you to remove purulent sputum at lung abscess or pneumonia when other medications are ineffective.

ACC is prescribed to prevent attacks of bronchial asthma, because it allows patients to breathe freely better than all other drugs. In this case, there is a decrease in the frequency of attacks. If a chronic disease does worsen, its course passes without the addition of opportunistic microflora, which significantly alleviates the person’s condition.

People who have suffered complications from an acute respiratory viral infection in the form of a dry cough and difficulty breathing use this remedy. After a short course of treatment, they fully recover from the disease.

If your doctor recommends this medicine, then there is no need to doubt whether you can drink ACC for a dry cough. This drug is recommended by the manufacturer to treat this symptom. It can be taken for such diseases and pathological conditions respiratory organs, such as:

bronchitis of any form;
inflammatory processes in the trachea;
lung abscess;
pneumonia;
COPD

The ability of the active substance to normalize secretions secreted by the respiratory system allows one to take ACC not only for the treatment of dry cough, but also to normalize the condition of inflammation maxillary sinus and middle ear. The inclusion of this medicine in complex therapy allows you to speed up the recovery process for these diseases.

On a note! Medicine can be taken long term for cystic fibrosis and other pathologies associated with poor sputum production and respiratory disorders.

How do patients feel about this medicine?

All patients taking ACC leave only positive reviews about this active substance for dry cough. A drug synthesized from an amino acid is considered the most safe drug, forcing the body to stimulate processes leading to recovery.

Pediatricians prescribe the medicine in a minimal dose to children suffering from complications after ARVI. It can be syrup or powder diluted in water. The resulting drink has a pleasant taste, and the children agree to drink it throughout the course of treatment. The drug gives a good expectorant effect, and the cough goes away within a few days after starting treatment.

Many parents use it constantly for children when they develop a non-productive form of cough. They note that after using this remedy, the cough always becomes moist, and the child’s condition improves.

Adult patients turn to ACC treatment after unsuccessful attempts treat dry cough with other medications. People taking this medicine indicate receiving quick results in the most difficult cases. Many consumers like that ACC does not fight the cough reflex, but effectively removes phlegm. When using it, the cough may intensify, which means the beginning of active separation of sputum from the bronchi.

Those who traditionally use this remedy like the form of the drug. Quickly dissolving granules in bags allow you to prepare a drink that is pleasant to drink after a meal. Other users of this medication like the tablet form. Effervescent tablet does not contain sugar. The manufacturer tried to give it the taste of a mineral drink. It can be used to treat people suffering from diabetes.

When to stop taking the drug

Acetylcysteine is well tolerated by the body in the doses recommended by the manufacturer. It perfectly removes phlegm, speeding up recovery. Despite the fact that the active substance is an amino acid, its excess in the body can lead to side effects. Allergic reactions occur no more often than 1 case in 1000, but if they occur, you should stop taking the medication and inform your doctor.

Important! Pathological reactions from the respiratory system are observed in 1 in 10,000 patients. This may be shortness of breath or bronchospasm, which is often observed in people with bronchial asthma.

Some patients with the same frequency of cases experience complications in the functioning of the digestive organs. They appear after taking dosage form heartburn, nausea, vomiting, diarrhea. To reduce the chance of side effects in digestive system, the medicine is taken after meals.

The ACC drug has complete contraindications. It should not be taken if intolerance to the active substance or other components of the drug is detected.

acute ulcerative gastritis;
bleeding from the lungs;
fructose intolerance.

The active substance accumulates in all fluids and penetrates the placental barrier. It should not be taken by women during pregnancy or nursing mothers.

With prolonged use, the drug may cause allergic reaction, because it participates in the metabolic processes of histamine. Most often this causes itchy skin.

Its ability to thin mucus can cause a runny nose. From long-term use the adrenal glands suffer, and the esophageal veins dilate. Therefore, patients forced long time taking ACC should be done under medical supervision.

Acetylcysteine passed clinical trials, and its capabilities are still being studied by scientists. It is easily tolerated by the body daily dose 500 mg per 1 kg of weight. With an intentional overdose, the side effects of gastrointestinal tract, which stop after the active substance is completely removed from the body. Fatal poisoning The effects of this remedy can only occur when a person takes a huge dose of the drug in one go. This will amount to several dozen packages at once, which cannot be done in everyday life.