What tests are needed for eco. Preparing a man for the IVF procedure. Tests for IVF: gynecological examination

Quite a complex method of conceiving a child.

Analyzes

Therefore, before moving on to it, it is necessary to do examinations. They include taking tests. These studies will be an indicator of a woman’s health. Since the upcoming event requires healthy condition organism, then the number of studies is quite large.

You should also be aware of the time frame during which IVF tests are valid.

Since a thorough examination of the female body is necessary, there are mandatory procedures. And also if any pathologies are detected, there are recommended tests for IVF. They need to be taken for a more accurate diagnosis of a particular disease or deviation from the norm. You should know that IVF puts quite a serious strain on the body. Therefore, it is better to identify everything at the preparatory stage possible risks and be prepared for any complications or refuse the procedure.

Tests for IVF need to be taken not only by the woman, but also by the man. After meeting the couple and studying the previous examination, the doctor prescribes necessary procedures both man and woman. You should know that there is a certain period when IVF tests are valid. Suitability may vary from person to person. Therefore, when planning this event, it is worth remembering this.

Research for two

List of tests for IVF for two partners:

1. Blood test for AIDS, syphilis, HbsAg, HCV and herpes. These results are valid for 3 months.
2. Microscopy of the genital organs. Valid for one month.
3. Examination for the presence in the body of infections such as chlamydia, herpes, ureaplasma, mycoplasma. results this survey valid for 1 year.
4. The doctor will also ask you to provide the couple with a previous examination.

For a man

List of tests for IVF that the husband must undergo:

1. First of all, he needs a morphology and MAR test. Exist certain recommendations that must be observed before the study. A man should abstain from sexual activity before taking a spermogram. The minimum period is 2 days, and the maximum is 7. One week before the test, you need to avoid baths, saunas and drinking drinks containing alcohol.
2. If necessary, according to indications, the doctor prescribes a consultation with an andrologist.
3. Karyotype. Also prescribed according to the patient's indications.

For the wife

Tests before IVF that the wife must undergo:

Additional examinations of the female body

There is also a list of tests for IVF that can be prescribed to a woman according to her indications. Passing them is not mandatory. But it is recommended to implement them. Since IVF is a serious burden on a woman’s body. This is due to hormonal stimulation of the body. This procedure may cause complications in female body. Especially if at the time of its implementation there are failures of any systems. Therefore, it is better to undergo a thorough examination and then decide to undergo IVF. Below is a list of procedures that the doctor may additionally prescribe:

1. Visit to a geneticist, karyotyping.
2. Hysteroscopy.
3. Laparoscopy.
4. Examination of the uterus.
5. Survey fallopian tubes.
6. Examination of the female body for the presence of antibodies such as antisperm and antiphospholipid.
7. The doctor can also give a referral to specialists if the woman has indications. This must be done to confirm or refute a particular diagnosis.

Since there are cases when a couple really wants to have a child and turns a blind eye to what is possible for the woman’s body. However, there is a possibility that existing diseases will worsen after the procedure. Or new ones will arise. Pregnancy itself is a test for the body. And IVF, due to hormonal stimulation, poses a double threat. Therefore, all factors must be taken into account women's health, ranging from age to examination results.

Conclusion

Now you know what tests you need to take for IVF. We also indicated the validity period of the results of a particular study. We hope that the information in the article was useful to you.

• Evgeniya

  I would like to express my deep gratitude to Irina Gennadievna Torganova. If it weren’t for her, I would hardly have decided on this procedure. I just trusted the doctor, and she told me what to do and how to do it. Sometimes it even seemed like you were left with no choice. But that's not true. Irina Gennadievna simply did not give either time or reason for doubt. I had IVF in September 2016. Despite the fact that I was already 40 years old at that time, and the man was 56, everything worked out on the first try and in a fresh protocol. The pregnancy was very easy. My Treasure has already grown up (we are 1 year and 7 months old) and weighs 17.5 kg and 89 cm. We will grow a little more and will definitely come to thank all the clinic staff. Thanks to all the staff of the clinic and good luck to those who are now on the path to their happiness or still doubt whether to undergo the procedure.

• Irina

  We would like to express our deep gratitude to the entire team of the clinic For Birth. After an unsuccessful IVF attempt at another clinic, we decided to go to this clinic under compulsory medical insurance. Unfortunately the first attempt was unsuccessful. But we didn’t give up, we still had cryoshkas. Thanks to Irina Gennadievna Torganova, the cryo protocol was successful. In March 2018, we welcomed a wonderful son and daughter. You are doing a miracle! And give the happiness of being parents! God bless you!!!

• Vita

  You know, I can confidently say that Zarozhdenie employs first-class specialists who value and love their work and care about their patients. I had the chance to meet this clinic in 2017. Before, I couldn’t even think that something like this was possible. I’m not a small girl, I’ve turned 30, I’ve heard about eco, but I haven’t gone into details. But 30 years crept up unnoticed, and my husband and I have been living for 5 years. We were also overtaken by a conversation about children. After talking, we realized that we were both ready for procreation. Apparently, at that time fate laughed very loudly, because at the hospital they told me something like “uh, no, my dear, you won’t be able to have children anymore.” I am a positive person by nature and not at all an alarmist. Therefore, having thought about this phrase sensibly, I went directly to Origin, it so happened that it turned out to be the closest at that time, and I just needed a paid clinic. It was there that they told me everything in detail about the eco procedure, about the additions and varieties. The next day I already dragged my husband there. He listened to everything and agreed. Our doctor: Mazur Sergey Ivanovich. Very cool, gives his best to work. I am so glad that after all the torment we found a way out and are now waiting for the birth of our baby.

• Anna

  Origin in Moscow – best clinic, which came across my path. Let me start with the fact that in the struggle for the opportunity to have children, I was far from alone. medical center and not in just one clinic. I went through all possible and impossible procedures and studies. Was treated and traditional medicine, in Russia and abroad, I even went to holy places and kissed the relics. The effect is zero. Mine first ex-husband actively supported me in everything, and then abandoned me and went to live with a colleague who was pregnant by him. I decided not to give up, but to keep trying. Finally, it was time for IVF. The first attempt in one very famous center in Moscow is a flyby. The second attempt is there - a flight. The third attempt, on the advice of a friend in Ivanovo, was a success, and the fourth in Zazrozhdenie was a success. Finally, I sighed calmly, I will have children!

• Tatiana

  Contacted your clinic after long-term treatment from infertility. It was a huge blow for my husband to find out that he was the reason that I couldn’t get pregnant. But the doctors at your center performed a miracle! They restored the husband’s faith in himself and, through the Ixi procedure, conception still occurred. Heartfelt thank you for our newborn son!

• Faith

  I tried to get pregnant for five years. By all measures, my husband and I were absolutely healthy. As a result, a diagnosis was made - idiopathic infertility. The doctors at your center decided to carry out eco + ixi procedures. My husband and I were thoroughly prepared and everything went smoothly. top level. I got pregnant with twins and now we are happy parents. Low bow to you!

Since 2016, infertility has been included in the number of cases subject to compulsory health insurance. Thus, citizens can receive an expensive IVF procedure, fully paid for from the compulsory medical insurance fund. Besides insurance policy You must have a medical certificate declaring the couple infertile and a completed health examination sheet for both partners. What types of tests and studies need to be taken before IVF for both men and women? What is the compulsory medical insurance survey sheet used for, what data is entered into it? What is the complete list of tests and studies that need to be taken for the IVF procedure under compulsory medical insurance? We will answer these questions in this article.

Regulatory framework for IVF under compulsory medical insurance

At the end of October 2012, the Russian government decided to include IVF in the free state medical care program. Since 2013, in vitro fertilization has been financed through mandatory funds. health insurance. The state is interested in increasing the birth rate and is ready to help childless families who want to have offspring. These intentions are confirmed in the relevant regulations:

• Order of the Ministry of Health of the Russian Federation dated August 30, 2012 No. 107n “On the procedure for using assisted reproductive technologies, contraindications and restrictions on their use” is still the main document for preparing for the procedure in vitro fertilization. According to this order:
  • not only registered married couples, but also civil partners, as well as single women have the right to treatment of infertility using ART;
  • for admission to the IVF procedure, a diagnosis of “infertility” and a conclusion about the ineffectiveness of the treatment are required;
  • a basic list of tests for partners has been established. Based on their results, couples with the highest probability of pregnancy are determined - they are the first to receive the right to pay for IVF under compulsory medical insurance.
• Order of the Ministry of Health of Russia N 565n dated August 12, 2013 “On approval of the list of types of high-tech medical care“- in accordance with it, the list of causes of infertility subject to IVF treatment was expanded, including HIV infection;
• The program has been operating in Russia since 2015 and guarantees state aid in the treatment of infertility for everyone with a compulsory medical insurance policy.

In accordance with the regulatory legal acts listed above, a patient who has received a referral for IVF is included in the waiting list in order of priority and has the right to choose a clinic - public or private - from the list of participants in the program. Moreover, in case of failure, the citizen can be included in the queue again for a repeat procedure.

What types of infertility does IVF treat?

The first step to obtaining a referral for an IVF procedure is to establish a diagnosis of infertility. Gynecologist antenatal clinic or a paid clinic prescribes necessary examinations to find out the cause of a woman’s infertility. Such examinations include:

• Studying hormonal levels body (the level of eight hormones is determined);
• Ultrasound of the uterus and ovaries;
• Laparoscopy and hysterosalpingography - to check the condition of the fallopian tubes;
• Hysteroscopy - examination of the inner surface of the uterus.

A man’s fertility is checked using laboratory tests such as a Kruger spermogram, a general urine test, and also mandatory check hormonal levels. Once the diagnosis is made, a course of treatment lasting up to two years is carried out. If pregnancy has not occurred during this period, the attending physician gives recommendations for the use of ART. His vote is taken into account by the commission of the Infertility Treatment Center, which can refer the couple to the clinic for this procedure. To be referred for IVF by Compulsory medical insurance necessary is not only a confirmed diagnosis, but also a conclusion about the ineffectiveness of the forms of therapy already performed.

With the increase in the number of protocols, the effectiveness of IVF increases: the first time, pregnancy occurs in 33% of women aged 25-40 years, after the second procedure - in 48%, and after the third - in 54% of women. Pregnancy ends with a successful birth in 80-85% of cases, and in 31% happy couples Twins and even triplets are born.

Diagnosis of infertility unknown origin placed in approximately 15% of cases. In such a situation, the couple may be offered IVF treatment, especially if there is no effect from other treatment methods, since in some married couples there is actually a kind of block that prevents fertilization. In 2017, the following diagnoses are indications for IVF: female infertility(with code name according to ICD-10):

• Obstruction of the fallopian tubes - N 97.1;
• Uterine pathologies - N 97.2;
• Diseases cervical canal- N 97.3;
• Insufficient quantity or low mobility of sperm in a partner - N 97.4;
• Ovarian cystosis - E 28.2;
• Congenital ovarian dysfunction - E 28.3;
• Impaired ovarian function as a result of treatment - E 89.4;
• Endometriosis - N 80;
• Uterine leiomyoma - D 25.

Modern medicine has a fairly large arsenal of drugs used to treat infertility. At the same time, it is necessary to understand that the choice therapeutic method primarily due to the reasons that led to infertility. It is worth remembering that an extract from the antenatal clinic containing a diagnosis of “infertility” indicating the ICD-10 code is the first document in the list necessary papers to undergo the IVF procedure.

Compulsory medical insurance examination sheet

To prepare for IVF, both partners receive an examination sheet - a form with full list necessary tests. They must identify whether there are factors in the couple’s health that would make the IVF procedure impossible or would sharply reduce its effectiveness. Indicators of reproductive capacity of partners are first on the list. For a woman, this is the level of AMH in the blood - the so-called Anti-Mullerian hormone. It shows how many active eggs capable of fertilization the expectant mother has. Currently in Russia there are no legal restrictions for IVF based on age - the ability to conceive is indicated by normal level AMH (1-2.5 ng/ml). An indicator of male reproductive ability is a spermogram. If she detects sperm pathology, then in order to conceive she will need an expensive ICSI procedure, the costs of which are not covered by compulsory health insurance funds. The commission's decision will obviously not be in favor of this couple.

An example of the influence of the AMH indicator on admission to the IVF procedure

1. Patient N, age 28 years. AMH level is 8 ng/ml. This exceeds the norm by 2.5 times and indicates hidden pathology, exacerbation of a chronic disease or exhaustion of the nervous system.
2. Patient S, age 35 years. AMH level - 0.3 ng/ml. This is almost 3 times lower than normal and is not enough for effective fertilization.
3. Patient R, age 41 years. AMH level - 1.8 ng/ml. This is quite normal. For mammography and karyotyping, which are mandatory for patients of this age category, no pathologies were found.

Thus, highest probability Despite her age, patient R can receive a referral for IVF.

The second block of research is lab tests for determining infectious diseases: test for the presence of antibodies to pathogens in the blood and collection of smears from the external genitalia. These procedures are included in the list of mandatory for both partners.

The third block of the examination concerns the somatic status of the woman - how healthy she is to bear and give birth to a child. This includes fluorography, ECG, general blood test, urine test, examination by a therapist, etc. In total, a woman needs to undergo up to 30 years before the IVF procedure. various studies. This can be done in a short time in paid clinic- convenient, but expensive. It's best to contact your area's insurance agent and find out which necessary procedures You can't do it for free in the region. By combining tests in a paid clinic with free procedures under your insurance policy, you can undergo a full medical examination within 1.5-2 months. Analysis results from short term actions are entered into the examination sheet later than anything else - before visiting a therapist. He, the last of all specialists, has the right to vote in assessing a woman’s ability to bear a child.

List of analyzes and studies and their validity periods

Before planning a pregnancy, it is necessary to undergo a series of examinations and tests, which will allow you to identify and solve existing problems at the preparatory stage. The standard list of tests and studies carried out as part of the IVF procedure under compulsory medical insurance is presented in the table below.

Table - Examinations and tests required for IVF in 2017

The next step after taking the tests is to contact the Ministry of Health commission at the city or regional Infertility Treatment Center. Add to list necessary documents The application includes an extract from the medical history indicating the diagnosis and methods of treatment, an extract about the health status of the patient and her partner with all the results of the examination, a copy of the insurance policy, copies of passports, as well as an application requesting referral for treatment using ART. If the commission, which has the voting right, agrees to this, the patient is put on the waiting list. After this, all that remains is to wait for a referral for a procedure that gives the woman a chance to become a mother.

If a married couple decides to use the in vitro fertilization service, they are recommended to undergo a thorough medical examination, which will allow you to assess the condition of the body of both the expectant mother and the expectant father. Laboratory and instrumental tests for IVF make it possible to identify diseases of an infectious and non-infectious nature, which is extremely important before the onset of physiological pregnancy.

The outcome of in vitro fertilization largely depends on how thoroughly the body of a woman and a man was examined. Modern medical diagnostic procedures are aimed at identifying hormonal and other disorders. During a joint medical consultation, both spouses can receive a list of referrals for medical diagnostic procedures.

Patients who will soon use one of the reproductive methods are recommended to undergo general laboratory tests before IVF, such as determining Rh antibodies, blood type and Rh factor. These measures are necessary in order to avoid an immune conflict in the future between the maternal body and the developing fetus. Medical reproductive specialists highlight a list of necessary laboratory tests, which they recommend that every patient undergo without fail.

The primary task for reproductive specialists is to assess the hormonal levels of the expectant mother. Based on the information received, medical specialists draw conclusions about the causes of infertility, as well as options for selecting an in vitro fertilization protocol.

From 3 to 5 days menstrual cycle, every woman is recommended to undergo a laboratory test to check the level of gonadotropic hormones. These hormones include:

1. Luteinizing hormone. The main function of this biological compound is the stimulation of estrogen production in the female body. When the concentration of this hormone reaches peak values, the process of maturation and release of the egg (ovulation) begins in the female body.
2. Follicle stimulating hormone. This compound is produced in the pituitary gland. It is under the influence of this hormone that follicles form and mature in women, and spermatogenesis also occurs in the male population.
3. Prolactin. The site of prolactin production is the anterior pituitary gland. When a woman is pregnant, this biologically active compound is synthesized by the cells of the lining of the uterus.
4. Estradiol. In terms of activity, this compound occupies a leading position in the woman’s body. The site of estradiol production is the placenta, adrenal cortex and ovaries.
5. Somatotropic hormone. Synthesized by the cells of the anterior pituitary gland, somatotropin is a catalyst for the growth of the entire organism.

Starting from the 20th to 25th day of the menstrual cycle, every woman is recommended to take a blood test to measure progesterone levels. This substance is produced by the corpus luteum of the ovary and is responsible for normal course pregnancy. It is progesterone deficiency that leads to premature or spontaneous termination of pregnancy at different stages.

Very important point preparation for the implementation of in vitro fertilization is to assess the condition of the thyroid gland. If we talk about the role of this anatomical formation in the female body, then under its leadership everything is regulated metabolic processes. When assessing the condition of the thyroid gland, the patient undergoes laboratory tests to determine the level of hormones such as T4, T3, free T4, and thyroid-stimulating hormone.

Before using one of the in vitro fertilization algorithms, the expectant mother is recommended to examine her body for sexually transmitted infections. The presence of infectious agents in the body entails serious consequences both for the patient’s body and for the body of the future fetus. Many of the listed pathogens lead to the formation of anomalies and malformations of the fetus. Medical specialists are interested in laboratory data regarding the presence or absence of such infectious pathogens:

• Gonococci;
• Chlamydia;
• Mycoplasmas;
• Ureaplasma;
• Gardnerella.

In addition, the patient is prescribed such additional tests for IVF according to the protocol:

• Laboratory tests of a smear of vaginal flora for the degree of purity;
• Coagulogram;
• Testing for antibodies to hepatitis C and B;
• Test for syphilis and HIV;
• Cytological examination of smears from the cervical canal;
• Analysis for the level of antibodies to toxoplasma and rubella virus.

If according to the results bacteriological research pathogens of infectious and inflammatory diseases were found in vaginal smears, then the implementation of in vitro fertilization is possible only if complex treatment with subsequent recovery.

If a woman has previously undergone any laboratory or instrumental examination before IVF, she must provide the results to a reproductive specialist. The most valuable research results include:

• Hysterosalpingography images;
• Hysteroscopy;
• Ultrasound examination of the pelvic organs, abdominal cavity and retroperitoneal space;
• Magnetic resonance imaging of the brain, which has data on the condition of the pituitary gland and sella turcica;
• Results of laparoscopic examination of the fallopian tubes (if performed);
• Ultrasound of the mammary glands.

For men

Assessing the health of the future father is an equally important point in preliminary preparation for in vitro fertilization. As mandatory diagnostic procedures, the following list of tests for IVF according to the protocol is distinguished:

• Blood test for Rh factor;
• Determination of blood group;
• Test for antibodies to hepatitis C and B;
• Wasserman reaction (test for syphilis);
• Determination of antibodies to HIV.

Also a mandatory study is a spermogram, during which the quantitative and high-quality composition seminal fluid. It is thanks to this study that it is possible to assess the potential male body to conceiving a child.

Before delivery biological material, the man is advised to refrain from ejaculating for 4 days. It is important to remember that the period of abstinence should not be less than 2 or more than 7 days. If this period is prolonged, then spermatozoa with low motor activity will be detected in semen samples.

On the eve of the delivery of biological material, it is strictly forbidden to visit saunas and steam baths, drink alcohol and even smoke. If necessary, the attending physician may ask the expectant father to undergo a series of semen tests, which are carried out over 30-90 days.

To exclude infectious and inflammatory diseases, along with a general clinical analysis of blood and urine, a man is prescribed a study of urethral smears for urogenital infections. The list of potentially dangerous pathogens corresponds to that indicated in studies for women.

In addition to the above methods of examining the body, before in vitro fertilization, the preparatory stage involves compliance with the following additional conditions:

1. Examination of blood samples for prothrombin levels.
2. Assessment of blood glucose concentration.
3. Collecting a family history, which includes information about various pathologies By female line. The diseases of interest are diabetes and malignant neoplasms.
4. Conducting a general urine test, which includes assessing the levels of leukocytes, protein and glucose.
5. Biochemical study of blood samples.
6. Compiling a list of all infectious and non-infectious diseases suffered in childhood.

Enough important information for medical specialists are the timing of menopause and the nature of the course of labor in the mother of a woman who is preparing for in vitro fertilization.

In addition, it is recommended that each patient, before implementing assisted fertilization techniques, be brought into proper condition. oral cavity. We are talking about eliminating infectious and inflammatory foci in the mouth, which are potential sources of pathogens.

If necessary, medical specialists can expand the list of mandatory studies before performing IVF.

Genetic

A particularly important point in preliminary preparation for the implementation of in vitro fertilization is the genetic diagnosis of both spouses. This study allows you to assess the state of the genetic material of the future mother and father, as well as identify the risk of transmission hereditary diseases from parents to offspring. Genetic studies before in vitro fertilization are recommended in the following cases:

• Previously, there were cases of unsuccessful implantation of ready-made embryos, and there was also a frozen pregnancy;
• There are no common children;
• Each spouse is over 35 years old;
• There is asthenozoospermia or oligospermia in the spermogram of the expectant father;
• There are cases of transmission of hereditary diseases.

The most valuable genetic studies include:

• HLA typing;
• Laboratory test to detect hereditary diseases such as galactosemia, cystic fibrosis, spinal amyotrophy, as well as phenylketonuria;
• Karyotyping of both spouses.

Genetic research methods can reduce the risk of developing genetic and hereditary diseases in the unborn fetus. The purpose of this type of research is shown by married couples who have already encountered unsuccessful attempts to implant ready-made embryos.

If one of the spouses already has physical and mental healthy child, then genetic studies are assigned only to the second spouse. During genetic diagnostics, medical specialists evaluate the structure and condition of chromosomes, since their anomalies lead to intrauterine mutations and miscarriage.

The so-called HLA typing is laboratory method histocompatibility assessment. If the diagnostic results of the expectant mother and father contain matching loci, then there is a high risk that the immune system expectant mother will reject the fruit. If such results are present, the couple is recommended to have a face-to-face consultation with an immunologist.

Validity periods

Along with the question of what tests are needed for IVF, future parents are interested in the validity period of the results obtained. These numbers directly depend on the type of medical diagnostic procedure. The relevance of the results is as follows:

1. Vaginal smears, urinalysis, general clinical analysis blood, blood biochemistry, coagulogram - 10 days;
2. Bacteriological examination of urogenital smears - 30 days;
3. Cytological examination of a smear, PCR from the cervical canal, fluorography, colposcopy with biopsy - 1 year;
4. Analysis for syphilis and HIV - 3 months;
5. Determination of blood group and Rh factor - indefinitely;
6. Conclusion of an endocrinologist and therapist - six months;
7. Spermogram and a woman's hormonal background - individually.

After the statute of limitations for the tests has expired, the couple needs to update the research results.

List (video)

Preparation for the in vitro fertilization procedure involves numerous examinations aimed both at identifying the cause of infertility and at eliminating factors that could become a contraindication to IVF. Scroll mandatory tests is recorded in one of the main documents regulating ART in Russia - the Order of the Ministry of Health “On the procedure for using ART.”

The order was adopted in 2013, since then no changes have been made to the list of tests, so the 2015 list is also relevant in 2016 - for receiving or joining the program. All studies are divided into two groups: to identify indications for the use of ART and to determine contraindications. We list them, indicating the average cost in Moscow clinics and laboratories.

Research to determine the causes of infertility and indications for ART

1. Blood test for group and Rh factor (from 550 rubles).

2. Assessment of endocrine status; First of all, studying hormonal levels. Blood is donated for hormones on days 3-5 of the cycle, with the exception of progesterone and estradiol, which are donated on days 20-22 ( best option– a week after ovulation). The day before the test, it is important to eliminate smoking, alcohol and emotional stress, and give up physical activity and from taking certain medications (their list is discussed with your doctor). Blood is donated on an empty stomach, in the morning.

• follicle-stimulating hormone;
• luteinizing hormone;
• estradiol;
• growth hormone;
• prolactin;
• thyroid hormones (T1-T4 and TSH);
• progesterone.

Addendum to laboratory research are instrumental - transvaginal ultrasound for examination of the uterus and ovaries.

average cost analysis to determine the level of one hormone – 550 rubles. Many clinics offer comprehensive programs for studying the female hormonal profile (from 5,000 rubles)

3. Assessment of pipe patency. This is done primarily by carrying out instrumental studies– laparoscopy and hysterosalpingography.

4. Study of the condition of the endometrium. The main method is, which involves examining the inner surface of the uterus and biopsy ( diagnostic curettage) with histological examination.

Identification of contraindications

Contraindications to in vitro fertilization - both absolute and relative - are general diseases, therefore, everyone who plans to join the ART program needs to do an ECG, fluorography, ultrasound of the abdominal cavity, thyroid gland and pelvis, get an opinion from a therapist and specialists, if any chronic diseases. Women over 35 should have mammography results, and women under 35 should have breast ultrasound. In addition, you need to undergo a number of tests.

1. Analysis for the presence of antibodies. A number of diseases, not presenting a danger in normal situation, during pregnancy can have serious Negative influence for the fruit. Blood tests for the presence of antibodies to the following diseases(from 550 rub.):

• herpes virus;
• toxoplasmosis;
• rubella.

2. Blood for HIV, syphilis, hepatitis. The cost of one analysis is from 500 rubles. Some laboratories offer comprehensive programs, including determination of HIV, hepatitis, and syphilis in the blood. Price – from 1700 rub.

3. Clinical and biochemical tests blood, which allow us to identify common diseases, work disorders individual organs. The price is from 700 rub. for clinical analysis up to 5500 for advanced biochemistry.

4. to assess blood clotting (1200-3500 rubles, depending on the set of indicators).

5. Flora smear to assess the cleanliness of the vagina and the absence (or content of normal quantity) microorganisms such as:

• yeast;
• Trichomonas;
• streptococci, staphylococci;
• gonococci;
• coli.

The cost of the study itself starts from 500 rubles, you will have to pay separately for collecting the material (from 400 rubles)

6. Examination for the presence of urogenital infections and chronic infectious diseases, which involves taking a smear. The doctor collects biomaterial from the mucosa, after which it will be studied PCR methods or RIF. Before taking a smear, it is important to abstain from sexual intercourse and not to use vaginal tablets, suppositories, douching. This method reveals:

It makes sense to pass comprehensive study, since it involves taking one smear for all indicators. average price complex – from 3200.

7. General urine test to assess kidney function and the absence of infection in bladder(from 200 rub.)

8. Colposcopy with (from 1200 RUR)

If abnormalities are detected in the tests, do not panic. Most contraindications are relative, that is, you can join the program after eliminating factors that could affect negative impact. For example, in the absence of antibodies to rubella, vaccination is recommended, three months after which you can begin the IVF procedure.

List of studies for men

The list of tests required for IVF has also been compiled for men. Most of them are the same as the “female” version, but there are some peculiarities. Like women, they need to receive fluorography results and a physician’s report. In the list of laboratory tests:

• blood test for Rh factor and group;
• antibodies to HIV and hepatitis;
• test for syphilis;
• urogenital infections – necessary tests the same as for women;
• smear on flora from the urethra;
• determination of antibodies to the diseases listed above in the blood;
• . If it is detected, another test is prescribed - an antiglobulin reaction. Basic cost – from 1500 rubles.

Tests after IVF

After unsuccessful IVF are appointed additional examinations to identify reasons

The first test that a woman needs to take after the in vitro fertilization procedure is , which is taken approximately two weeks (sometimes on the 12th day) after the transfer took place. Its results allow us to conclude whether pregnancy has occurred or the attempt was unsuccessful.

After a failure, it is first of all important to find out its reasons, so that when you try again, you can minimize the effect. negative factors and increase the chances of a favorable outcome. Therefore, it is possible that the doctor will prescribe additional research. Their list might look like this:

1. An analysis for the presence of antiphospholipid antibodies, which is prescribed to diagnose diseases of the immune system.
2. Detection of antibodies to hCG. The reason for their formation in the body is not fully understood, but the mechanism of action is known: antibodies disrupt the binding of receptors corpus luteum And human chorionic gonadotropin, which leads to changes in hormonal levels and termination of pregnancy.
3. to determine histocompatibility antigens in both spouses.
4. Immunogram for studying cytotoxic cells.
5. Extended hemostasiogram with determination of lupus coagulant, D-dimer and other criteria.
6. Detecting chromosomal abnormalities by studying.

Unlike those listed above, these tests are not mandatory and are prescribed at the discretion of the doctor only after an IVF attempt (or several attempts) has failed.

Validity periods

Each analysis has an “expiration date”. It refers to the period during which the research data is considered valid and relevant. If more time has passed since the test, you will have to take the tests again to receive a quota or enter the compulsory medical insurance program. Let's list the deadlines.

One month:

• flora smears;
• blood tests for biochemistry and clinical;
• Analysis of urine;
• hemostasiogram.

Three months:

• blood for syphilis and hepatitis;
• blood for HIV.

Six months:

• ELISA (antibodies to rubella, toxoplasmosis, genital herpes);
• PCR (urogenital infections);
• spermogram.

One year:

• smear for oncocytology;
• hormonal studies;
• fluorogram;
• electrocardiogram;
• data from pipe patency studies;
• Ultrasound and mammography.

There are no expiration dates and tests for group and Rh factor, as well as karyotyping, are performed once.

Mandatory examinations before IVF

Where to get tested

Analyzes that are required to participate in compulsory medical insurance programs and to obtain a quota, you can take it for free, with a referral from a local therapist or from a gynecologist from a antenatal clinic. This option is inconvenient because it requires a lot of time, since most studies are done by appointment. You will have to very carefully and accurately calculate the timing of the tests so that they are all valid by the time you submit the documents for IVF.

The second option is convenient, but expensive: paid tests at the clinic where the procedure will be performed, or in independent laboratories. Many clinics today offer comprehensive programs, the cost of which may include consultations with specialists. The average cost of the complex is from 30,000 rubles per spouse, it does not include instrumental manipulations and some actions for collecting material (for example, a smear for oncocytology).

Finally, the third option is a combination of free and paid analyzes. It makes sense to carry out some studies in the laboratory upon referral from the antenatal clinic (for example, general tests blood and urine, biochemistry). Others, especially complex ones and requiring special equipment, can be done in a paid clinic.