Is it worth taking Triampur for weight loss? When to take the drug with caution. International nonproprietary name

Triampur (or Triampur Compositum) is part of the group of combined diuretics.

Pharmacological action of Triampur

Triampur is aimed at achieving hypotensive and diuretic effects.

The effect of the drug is due to the pharmacological properties of its constituents. active ingredients– hydrochlorothiazide and triamterene.

Hydrochlorothiazide belongs to the group of diuretics, whose action is based on reducing the reabsorption of sodium ions in the distal tubules. The substance also promotes the removal of potassium, sodium, water and chlorine ions from the body, while slowing down the process of excretion of calcium ions. Taking high doses of the drug entails increased excretion of bicarbonate from the body, which is explained by inhibition of carbonic anhydrase.

The action of Triamterene is aimed at enhancing the excretion of water and sodium ions from the body and reducing the excretion of hydrogen and potassium ions. In addition, the drug is able to slow down the process of exchange of sodium ions for hydrogen and potassium ions in the distal tubules.

Triampur is characterized by rapid absorption in the gastrointestinal tract. The maximum therapeutic effect, according to the instructions for Triampur, is achieved 4 hours after administration.

Release form

Triampur is available in the form of round tablets yellow color. The edges of the tablets are beveled and there is a mark on one side. Quantity: 50 pcs. The tablets are packaged in glass bottles.

Indications for use of Triampur

Medical reviews about Triampur allow us to call the drug effective therapeutic agent used in the treatment arterial hypertension and edema syndrome of various origins (including heart failure, nephrotic syndrome and liver cirrhosis).

Contraindications

The instructions for Triampur warn of the presence of a number of contraindications for use. Before you start using them, you should familiarize yourself with the list below:

• anuria;
• renal failure in chronic form;
• acute glomerulonephritis;
• hepatic coma and precoma, as well as others severe violations liver functioning;
• disturbances in the metabolic process of electrolytes that cannot be corrected. These include hyponatremia, hyperkalemia, hypokalemia, hypercalcemia;
• hypovolemia;
• pregnancy and lactation period;
• allergy to sulfonamides.

Also, before you start using Triampur, you should consider a number of precautions, according to which the drug is recommended to be taken with caution for the following types of ailments:

• impaired renal or liver function;
• urolithiasis disease;
• gout;
• diabetes;
• deficiency (or suspicion of it) folic acid. In particular, with a disease such as liver cirrhosis caused by excessive alcohol consumption;
• risk of developing acidosis;
• age up to 18 years (effect of Triampur on children's body not installed).

Instructions for use of Triampur

It is recommended to take the tablets orally, some time after eating, with water and without chewing. During the use of Triampur, it is necessary to monitor the replenishment of fluid deficiency in the body.

The dosage of the medicine is selected by the doctor individually for each patient, however medical reviews about Triampur they call average dosages.

• For edema, the initial dose should be from 2 to 4 tablets, which should be taken in the morning and at lunch. Subsequently, the dose is adjusted based on the degree of dehydration of the body. The maintenance dosage of Triampur in this case is one tablet per day, which is best taken in the morning. Another option is two tablets, which should be taken every other day, but both should be taken on the same day (one in the morning and one at lunch). As prescribed by the doctor, the dose can be increased to 4 tablets per day (two in the morning and in the afternoon);
• For arterial hypertension, the initial dose of Triampur is two tablets in the morning and at lunch. If necessary, the dosage can be reduced to 2 tablets per day (the dosage regimen is the same);
• With concomitant therapy during the treatment of heart failure with cardiac glycosides, the minimum dose of Triampur is 2 tablets per day. It is allowed to increase the dosage to 4 tablets per day (2 in the morning and at lunch);
• When kidney function decreases, the maximum permissible dose Triampur and drug analogues per day is 1 tablet.

Side effects when taking Triampur

The use of Triampur can cause wide range side effects . It is necessary to notify your doctor if any of the adverse reactions described below occur:

• vomiting, nausea, diarrhea, pain and stinging in epigastric region, constipation, dryness in oral cavity, thirst. In rare cases, symptoms of hemorrhagic pancreatitis and acute cholecystitis may appear;
• increased drowsiness, uncoordinated movements, fatigue, headache, irritability;
• muscle weakness, muscle tension, cramps calf muscles;
• rapid heartbeat, disturbances heart rate and regulation of blood circulation, dizziness, fainting, decreased blood pressure;
• an increase in the blood urea and creatinine content, which is temporary, a violation of the concentration of sodium, chlorides, magnesium, potassium in the body, an increase in the concentration uric acid in the blood, which can lead to the formation urinary stones and gout attacks, increased blood sugar levels;
• various visual impairments, worsening myopia;
• leukopenia, agranulocytosis, aplastic anemia, megaloblastic anemia, hemolysis;
• allergic reactions in the form of urticaria, skin itching, systemic lupus erythematosus, fever, anaphylactoid reactions, the appearance of icteric coloring of the mucous membranes, sclera and skin. In rare cases, pulmonary edema may occur.

Triampur and analogues

Drug analogues include drugs such as:

• diazide;
• Apo-Triazide;
• Triamtel;
• Vero-Triamtezid.

Storage conditions

Sincerely,

General characteristics. Compound:

Pharmacological properties:

Indications for use:

Important! Get to know the treatment

Directions for use and dosage:

Features of application:

Side effects:

Interaction with other drugs:

Overdose:

Storage conditions:

List B. At a temperature not exceeding 30°C. Keep out of the reach of children! Shelf life: 3 years. Do not use after the expiration date stated on the package.

Vacation conditions:

On prescription

Package:

50 tablets in a clear glass bottle with a polyethylene stopper. 1 bottle in a cardboard box along with instructions for use.

"Triampur" is a combined remedy, the effect of which is explained by the action of the components included in it. It has diuretic and hypotensive properties. It contains hydrochlorothiazide, which is a diuretic with medium potency and at the same time a substance that helps preserve potassium.

Composition and release form of the drug "Triampur"

The instructions inform you that one tablet of the drug contains

active ingredients consisting of:

Hydrochlorothiazide in the amount of 12.5 mg,

Triamterene - 25 mg;

excipients:

Lactose monohydrate;

Potato starch;

Polividone K25;

Highly dispersed silicon dioxide;

Sodium starch glycolate;

Magnesium stearate.

The tablets are packaged in bottles of 50 pieces.

Indications for use of the drug "Triampur"

The instructions indicate the use of the drug for arterial hypertension of various origins (chronic heart failure, kidney pathology, liver disease).

Quite often in practice, the drug "Triampur" is prescribed to children under one year of age as a diuretic for

Contraindications

Not allowed to be used for:

Hypersensitivity;

Kidney failure;

Acute glomerulonephritis;

Severe liver dysfunction;

Electrolyte metabolism disorders that cannot be corrected: hypokalemia, hyperkalemia, hypercalcemia, hyponatremia;

Hypovolemia.

Method of use of the drug "Triampur"

The instructions instruct you to swallow the drug after meals, do not chew it and take it with a small amount of liquid. Doses are determined by the doctor for each patient individually. For adults and children weighing more than 50 kg approximate therapeutic dose-2-4 tablets - two doses/day. As maintenance therapy - one tablet/day.

Pregnancy and lactation period

The medicine should not be used during pregnancy, and should be discontinued during treatment. breast-feeding.

Interaction with other drugs

Antihypertensive and diuretic tricyclic antidepressants, vasodilators, phenothiazines stimulate the hypotensive effect; and NSAIDs, on the contrary, weaken it.

The drug "Triampur" (the instructions emphasize this) weakens the effect of anti-gout, antidiabetic drugs, adrenaline and norepinephrine. But it enhances the toxic effect of lithium, the side effects of salicylates on the central nervous system, curare-like relaxants, glycosides, and cytostatics.

Side effects

"Triampur" can cause negative impacts in the nervous system with symptoms of ataxia, drowsiness, headache, nervousness, etc.

In the cardiovascular system, its use sometimes causes changes in ECG, heartbeat, lowering blood pressure, etc.

Side effects in the gastrointestinal tract manifest themselves in the form of nausea, vomiting, diarrhea, sometimes epigastric pain, and in some cases jaundice, etc.

IN exchange process substances are possible

Electrolyte imbalance, metabolic acidosis;

Increased levels of cholesterol, glucose, triglycerides;

Dehydration, hypovolemia, etc.

Prescription of the drug "Triampur" for children: reviews

Having analyzed a large number of reviews on the use of the drug "Triampur" in children under one year of age, we can come to the following conclusion. In the overwhelming majority of cases with ICP in children, this drug has proven to be very effective remedy. There is a significant amount positive feedback mothers to use this medicine in treating children. But since this drug has a fairly large number of contraindications, as well as an equally large number of possible negative effects, then it should be used only after being prescribed by a doctor. When the first signs of side effects appear, you should immediately consult a doctor.

How effective is the use of a medicine such as Triampur Compositum for weight loss? Reviews talk about the possibility of quickly losing weight without much effort. But the drug does not have direct indications for weight loss; isn’t this dangerous for health?

What is Triampur Compositum?

The drug "Triampur Compositum" is classified as a diuretic, a medication that has diuretic properties and is intended to be removed from the body. excess liquid. Their direct effect is aimed at the kidneys and inhibiting the reabsorption of sodium ions in the renal canals, due to which excess water is removed from the body.

In general, diuretics are used to combat edema, normalize kidney function, and lower blood pressure. Such drugs can also be used for poisoning, since they have the property of binding and removing toxins.

Indications for use

Direct indications for use, according to the instructions, are:

• swelling caused by heart disease, impaired kidney or liver function;
• excess potassium in the body;
• increased blood pressure;
• the presence of vegetative-vascular dystonia.

With diseases of the heart and diuretic system, sodium accumulates in the body, which contributes to the occurrence of swelling. Excess sodium also constricts blood vessels, which increases blood pressure and causes headaches. Triampur Compositum removes excess sodium from the body along with fluid, which quickly reduces blood pressure and eliminates swelling.

In case of poisoning, the main impact is on the kidneys, which cannot cope with large amounts of toxins. Taking Triampur Compositum helps remove toxic substances. The drug is quickly absorbed into the blood, so the result from taking it occurs after one to two hours, while the effect of the drug continues throughout the day.

How to take Triampur Compositum?

The method of using Triampur Compositum depends on the indications and body weight. If you weigh more than 50 kilograms, two tablets are usually prescribed twice a day, in the morning and at lunch. Treatment is completed by reducing the dosage and taking first one tablet at a time, and then one tablet per day.

When used simultaneously with medications for hypertension, heart disease or poisoning, Triampur Compositum is taken in an amount of no more than two tablets per day.

For swelling, the remedy is taken in the morning and at lunch, one or two tablets at a time, depending on the intensity of the problem. Availability kidney diseases involves taking no more than one tablet per day.

Triampur Compositum is prescribed by a doctor, who also determines the dosage of the drug and the duration of its use. At long-term use In no case should you suddenly stop using it; you must gradually reduce the dose, otherwise problems with fluid excretion and kidney function may occur.

"Triampur Compositum" for weight loss

Triampur Compositum is often used by athletes. The drug is especially often used in sports that require strict weight control, such as equestrianism or gymnastics. Bodybuilders often use this product to remove “excess” water from the body.

Triampur Compositum is used and ordinary people when you need to quickly get rid of several extra pounds in anticipation important event. And indeed, rapid weight loss is observed - in a few days you can lose up to 3-5 kilograms. However, do not forget that body weight decreases due to the removal of fluid, the lack of which can provoke health problems. In addition, there are many contraindications to taking the drug.

Contraindications for use

Despite the effectiveness of Triampur Compositum, there are certain contraindications to its use, in particular:

• hypersensitivity to the components of the drug, which becomes a direct contraindication for use;
• severe liver or kidney damage, glomerulonephritis ( inflammatory process in the kidneys), anuria (urinary retention), hepatic coma;
• increased concentration of potassium in the body;
• hypovolemia (decrease in total blood volume and imbalance in its constituent elements and plasma);
• gout;
• pregnancy, since the medicine easily penetrates the placental barrier and negatively affects the fetus;
• breastfeeding, as taking the product may harm the baby.

Side effects

Triampur Compositum should not be taken on an empty stomach, as this may cause nausea, vomiting or diarrhea. In some cases, taking the drug may be accompanied by side effects, such as:

• fast fatiguability;
• nervousness;
• voltage;
• dry mouth:
• headache;
• thirst;
• blurred vision;
• heart rhythm disturbance;
• muscle cramps or weakness;
• diarrhea or constipation;
• allergic reactions.

Adverse reactions in most cases are caused by improper use of the drug. This may be taken on an empty stomach, combined with other medications, or used with obvious contraindications. The occurrence of any adverse reaction requires immediate discontinuation of the drug until the provoking cause is determined.

Interaction of Triampur Compositum with other drugs

Triampur Compositum should be taken with extreme caution in combination with other medications. So simultaneous use with diuretics, hypertension, sedatives or vasodilators may provoke sharp decline blood pressure.

Combination with painkillers can negatively affect the kidneys, reducing glomerular filtration. In addition, by reducing the absorption of certain substances in the gastrointestinal tract, the concentration of potassium in the blood may increase.

The combination with cardiovascular diseases contributes to the emergence of potency. It is highly undesirable to take Triampur Compositum in combination with drugs containing lithium, as this can cause toxic damage to the body. Simultaneous use with adrenaline-containing drugs reduces the effectiveness of the latter.

What should you pay special attention to?

When deciding to take Triampur Compositum, you should pay attention to the following points:

• You should not take the drug if you are prone to the formation of kidney stones, since colloid imbalance due to taking Triampur can lead to changes in the kidney parenchyma and the formation of stones;
• in case of diabetes mellitus, Triampur can cause hyperglycemia and increased blood glucose;
• taking the drug is undesirable if there is a lack of folic acid, which can be observed in liver cirrhosis or alcohol abuse;
• at long-term use"Triampura" it is advisable to periodically check the concentration of potassium in the blood; diuretics can also provoke hypomagnesemia and an increase in calcium in the blood plasma;
• taking medication for gout may increase the level of urea in the blood;
• taking Triampur Compositum may slightly change some test results, in particular blood tests, thyroid examination, bilirubin level;
• When taking Triampur, it is advisable to avoid using complex equipment and driving a car, since a violation of the motor reaction may be observed.

Overdose

An overdose of Triampur Compositum may be accompanied by symptoms such as:

• a sharp decrease in blood pressure;
• dehydration and electrolyte imbalance, accompanied by nausea and weakness;
• asthenia, prolonged diuresis, increased fatigue, cardiac dysfunction, breakdown;
• dizziness and kidney failure;
• diuretic intoxication.

As such, there is no treatment for overdose. It is necessary to stop taking the drug. To improve your health as quickly as possible, it is recommended to induce vomiting or take Activated carbon, which will prevent the absorption of drug components into the blood.

So is it worth taking Triampur for weight loss? Reviews about it, of course, indicate its effectiveness this method, but the presence of serious contraindications and the likelihood of side effects casts doubt on the advisability of this method of weight loss. Still, Triampur Compositum is not intended for weight loss and cannot guarantee health safety.

Reviews

Anastasia Orlova, 27 years old, Kostroma:

I have known for a long time that diuretics help with weight loss. Therefore, when I needed to lose weight quickly, I decided to take Triampur Compositum. Within a week of use, body weight decreased by 3 kg. Of course, this can hardly be called healthy weight loss and it is clear that adipose tissue there is no impact, but how emergency method taking Triampur may be useful.

Sofia Becker, 33 years old, Kaliningrad:

I don’t have any particular problems with weight, but my “headache” was swelling; in the mornings a swollen woman with “bags” under her eyes would look at me from the mirror. Because of this, I even had to wake up for work 2-3 hours earlier in order to somehow get myself in good shape. The pharmacist at the pharmacy advised me to take Triampur Compositum when I shared my sorrows with her. I took it for two weeks, and gradually reduced its use in the third or fourth week. The drug really helped at least, so far there is no swelling, although the amount of liquid I consume remains the same.

Elena Korobova, 29 years old, Saratov:

I took Triampur Compositum on the advice of a friend who is actively involved in fitness and often visits the gym. According to her stories, many of those who play sports and watch their figure take this drug for quick drying. I took the medicine for three weeks, during which time the volumes really decreased - the waist became narrower and the stomach became smaller. I think that it is advisable to take the drug in combination with strength loads so that the results are maintained. I think I’ll decide to take the product again as soon as it appears free time for regular trips to the gym.

Marina Saenko, 26 years old, Tomsk:

I lost weight with Triampur; my colleagues’ craze for this drug had an effect, and they praised it as some kind of miracle remedy. My impressions of it are extremely contradictory - on the one hand, the product cannot be called ineffective, the weight actually decreases by several kilograms, but on the other hand, there is a completely uncomfortable state; personally, throughout the entire use, I was constantly accompanied by extreme thirst and severe weakness. Despite the effectiveness of the drug, I would not recommend its use to anyone.

Olga Mayer, 31 years old, Volgograd:

I once took Triampur Compositum as prescribed by a doctor. The drug is really good and helped a lot in treating my disease. However, I did not notice any weight loss from taking it. It may be good for eliminating edema, but it’s probably not worth taking as a means of losing weight. Before prescribing it, the doctor carefully examined me and monitored my health throughout the course, since there were no contraindications and side effects. of this medicine so many.

Raisa Pyanzina, 30 years old, Perm:

I heard that Triampur Compositum helps you lose weight quickly, and since I don’t have time to go to the gym, I decided to use this tool. Almost from the very first days I noticed that I began to get tired faster and often felt dizzy. By the end of the week of treatment, I almost constantly felt weak in my body, and I was also very tired of endless trips to the toilet, although I drank very little water. After taking the drug for a week and a half, I stopped using it, because no amount of beauty is worth such a mockery of one’s health.

Irina Dubravina, 32 years old, Lipetsk:

I took Triampur Compositum for the purpose of losing weight for two weeks. During this time I managed to lose almost 4 kg. But after I stopped taking the drug, the weight returned quite quickly. Just two weeks later, my 4 kg returned. That's why I don't consider Triampur suitable method weight loss. Rather, you can consider it an “ambulance” when 2-3 kg prevents you from getting into your favorite dress. In addition, the use of the drug is accompanied by increased urination and constant thirst, which does not contribute to good health at all.

Video

Trade name of the drug:

Triampur compositum ®

International nonproprietary name:

Dosage form:

pills

Compound

1 tablet contains:
active substances: triamterene 25,000 mg, hydrochlorothiazide 12,500 mg;
Excipients: lactose monohydrate 63,000 mg, potato starch 20.725 mg, povidone K 25 3.900 mg, magnesium stearate 1.300 mg, colloidal silicon dioxide 0.975 mg, sodium carboxymethyl starch 2.600 mg.

Description: yellow, round tablets with a score on one side and beveled edges.

Pharmacotherapeutic group:

ATX code C03EA01.

Pharmacological properties

Indications for use

Contraindications

Carefully– diabetes mellitus, gout, patients with impaired liver and/or kidney function, folic acid deficiency (in patients with liver cirrhosis).

Directions for use and doses

Orally, without chewing, with a drink a small amount water after eating. For edematous syndrome, the initial dose is determined by the severity of water-electrolyte metabolism disorders and is usually 1 tablet 2 times a day after meals, then it is possible to increase the dose to the maximum daily (4 tablets per day): 2 tablets after breakfast and 2 tablets after lunch.
When compensating for edema, they switch to maintenance therapy, 1-2 tablets every 1-2 days.
For arterial hypertension - the initial dose is 1 tablet per day (in the morning, after breakfast), then the dose is gradually increased. Maximum daily dose– 4 tablets.
In patients with impaired renal function (creatinine clearance - 30-50 ml/min.), the maximum daily dose is 1 tablet.

Side effect

From the digestive system: nausea, vomiting and sometimes diarrhea (when taking the drug before meals), pain and discomfort in the epigastric region, colicky abdominal pain, constipation, dry mouth, thirst, in isolated cases - hemorrhagic pancreatitis, and in the presence of gallstones - acute cholecystitis.
From the central nervous system: uncoordinated movements, drowsiness, feeling tired, headache, nervousness.
From the musculoskeletal system: muscle tension, muscle weakness, calf muscle cramps.
From the outside of cardio-vascular system: palpitations, decreased blood pressure, irregular heart rhythms and dysregulation of blood circulation with dizziness, confusion or a tendency to faint. Due to large loss of fluid and a decrease in circulating blood volume when using the drug in high doses and/or copious discharge urine, blood clots may form, embolism may develop, and in rare cases, convulsions, confusion, vascular collapse and acute renal failure.
From the side of metabolism: temporary increase in the concentration of nitrogen-containing substances excreted by the kidneys (urea, creatinine) in the blood (mainly at the beginning of treatment), disturbances in water-electrolyte balance, mainly a decrease in the content of sodium, magnesium, chlorides in the blood, a decrease or increase in potassium content (with prolonged continuous use of the drug), hypercalcemia, decreased glucose tolerance. An increase in the level of uric acid in the blood is possible, which may lead to gout attacks in some particularly predisposed patients, and the formation of urinary stones may occur. In sensitive patients, depending on the total dose of the drug taken, an increase in blood lipids may be observed. Due to an increase in the concentration of glucose in the blood, a latent form may appear or an existing form may worsen. diabetes mellitus. The drug may contribute to the accumulation of non-volatile acids in the blood (metabolic acidosis).
From the organs of vision: visual disturbances, worsening of existing myopia or decreased tear production.
From the hematopoietic system: aplastic anemia, leukopenia, thrombocytopenia, agranulocytosis, megaloblastic anemia with a previous deficiency of folic acid in the body, hemolysis resulting from the appearance in the blood of autoantibodies to the active substance hydrochlorothiazide with simultaneous use of methyldopa.
Allergic reactions: skin redness, itchy skin, urticaria, systemic lupus erythematosus, photoallergic exanthema, fever, hypersensitivity reactions (anaphylactoid reactions), severe inflammation of the blood vessels and non-bacterial inflammation of the kidney tissue (aseptic interstitial nephritis). In isolated cases, suddenly developing pulmonary edema with symptoms of shock has been described. The reason for this is probably an allergic reaction of patients to the active substance hydrochlorothiazide.
Others: icteric coloration of the skin, mucous membranes and sclera.

Overdose

Interaction with other drugs

Medicines that bind intensively to blood proteins ( indirect anticoagulants, clofibrate, non-steroidal anti-inflammatory drugs) enhance the diuretic effect of the drug.
Hypotensive effect vasodilators, barbiturates, phenothiazines, tricyclic antidepressants, ethanol enhance.
Triampur enhances the neurotoxicity of salicylates, weakens the effect of oral hypoglycemic drugs, norepinephrine, epinephrine and anti-gout drugs, enhances the effects (including side effects) of cardiac glycosides, the cardiotoxic and neurotoxic effects of lithium, the effect of curare-like muscle relaxants, reduces the excretion of quinidine.
When taken simultaneously with methyldopa, the risk of hemolysis increases. Cholestyramine reduces the absorption of Triampur.
Chlorpropamide when taken simultaneously with Triampur can lead to severe hypokalemia.
When combined with non-steroidal anti-inflammatory drugs, acute renal failure may develop.

special instructions

Release form

Storage conditions

Store at a temperature not exceeding 25°C.
Keep out of the reach of children.

Best before date

5 years.
Do not use after the expiration date stated on the package.

Conditions for dispensing from pharmacies

On prescription.

Legal entity in whose name the RU was issued: