Urticaria Tavegil or Suprastin which is better. Therapeutic properties of the drug "Cetrin". The use of suprastin in childhood

According to statistics, in every second household at least 6 allergens can be detected. About 50% of the population reacts to at least one allergen developed countries, and pet lovers and fashionistas who prefer white gold jewelry are at risk. This is probably why antihistamines occupy the top steps of the pharmacy sales rankings. Let's take a short look at two popular drugs Suprastin and Tavegil, which are prescribed for allergies.

What is the difference?

Despite the fact that both drugs belong to the group of antiallergic drugs, they have different composition. Suprastin contains chloropyramine, and Tavegil - clemastine.

Suprastin is produced in Hungary by the pharmaceutical plant EGIS in the form of:

• tablets 0.025 g,
• solution for injection 20 mg/ml.

Tavegil is produced by the Swiss pharmaceutical company Novartis in similar dosage forms with clemastine dosage:

• in tablets of 1 mg,
• in ampoules of 1 mg/ml.

Histamine is released from mast cells during a reaction to substances that are irritating or foreign to our body, which causes symptoms of hay fever, redness of the skin and inflammation of the mucous membranes. This reaction, initially developed in the process of evolution as a protective one, in our “allergenic” times becomes the cause chronic diseases and even bronchial asthma. Tavegil or Suprastin, as well as a number of other antihistamines help combat this.

Medicines do not affect the production of histamine, but block its binding to molecular cellular H1 receptors. This interrupts the chain of allergen-induced reactions and stops the development of characteristic symptoms.

Difference from new generation antihistamines

There are several generations of drugs of this kind:

The first generation of H1 blockers, due to their high solubility in fat, penetrates the blood-brain barrier well. Due to their less specific action, these substances bind not only to histamine, but acetylcholine and serotonin receptors of brain cells. This determines their sedative effect. In addition, they can cause other effects, for example, anxiolytic, antiemetic, anesthetic.

The second generation of H1 blockers was developed to make them more specific, prolong the effect and do not cause drowsiness. Nowadays, this group of drugs is the most popular in the practice of treating allergies.

Representatives latest generation antihistamine free side effects 1st and 2nd generation drugs: they do not cause sedation, are highly effective and have reduced toxicity to the heart.

Which is more effective and stronger?

Both drugs in question belong to 1st generation antihistamines and have similar effects. However, there is also a difference between Suprastin and Tavegil. Suprastin is used to treat emergency conditions due to its availability, rapid relief of symptoms, low toxicity and compatibility with other antihistamines. In Russia it is included in the list of vital drugs, and in western medicine does not apply.

Tavegil and other clemastine-containing brands are widely used throughout the world. There they are classified as over-the-counter medications. Antihistamine effect This medicine lasts approximately 2 times longer than Suprastin, and the hypnotic effect is less pronounced. It is believed that clemastine best relieves symptoms such as itching.

One of the first placebo-controlled studies, conducted in Danish clinics, compared the results of treatment allergic rhinitis in 155 patients. Clemastine was prescribed 1 mg 2 times a day. Patients underwent rhinoscopy and the course of active rhinitis was recorded. Clemastine resulted in statistically significant improvement compared with placebo and was well tolerated.

However, in clinical practice There are cases of allergy to clemastine itself. In addition, it has a proven fetotoxic effect (absolutely not during pregnancy!).

Because the if necessary long-term treatment addiction to H1 blockers occurs, there is a tactic of alternating them. Thus, Suprastin can be replaced with Tavegil or another drug of a similar kind. However, without established diagnosis can't be proper treatment Therefore, the information on our website is not a substitute for professional medical advice.

What is the price?

The instructions for Tavegil say that adults need to take it 2 times a day, one tablet. The course of treatment usually does not exceed a week, so a total of 14 pieces will be required. A package (20 pcs.) costs between 200 and 230 rubles.

Suprastin should be taken 3 or 4 times a day. However, despite the fact that the course requires 2 times more pills, its price is approximately 2 times lower.

Allergies are a common disease. Every third person has an immune response in the form of allergic reaction.

On pharmaceutical market There are many antiallergic drugs, but Suprastin takes the leading place.

The second most important is Tavegil. Let's consider both means and compare their effectiveness.

Antihistamines - what are they?

It can only be treated by taking antihistamines. Histamine is a substance that calm state the body is excreted in small quantities. When a foreign agent (allergen) enters, the hypothalamus is activated, producing a large number of histamine.

Are developing unpleasant symptoms- itching, lacrimation, sneezing, urticaria.

Free histamine leads to tissue swelling, bronchospasms and lowers blood pressure - as a result, anaphylactic shock develops.

To avoid running this pathological process, you need to take antihistamines. By suppressing the formation of free histamines, antihistamines reduce the manifestations of allergies, reducing symptoms to zero.

About drugs

These drugs are first generation antihistamines. Characteristic feature Antiallergic drugs of this type are blocking H1 receptors and cholinergic muscarinic receptors.

Features of Tavegil and Suprastin:

1. Overcoming the blood-encephalitis barrier, have an effect on the central nervous system. IN in rare cases may provoke agitation of the psychomotor system.
2. Call sedative effect – apathy and drowsiness develop. Constipation, arrhythmia and dry mucous membranes - others side effects from taking the drug.
3. The effect of taking the medicine visible immediately, but the effect of the drug is short-lived (up to 5 – 6 hours).
4. Duration of treatment more than 10 days addictive.
5. Use with caution for stomach ulcers.

In order to give a complete answer about which of the presented drugs is better, you need to familiarize yourself with each of them in detail.

Analyze all positive and negative actions and choose the most suitable option.

Suprastin – antihistamine, which became the first allergy medicine. Suprastin has been produced since 1937, during which time a large number of other antihistamines, but the effectiveness of taking Suprastin has remained to this day.

The main active ingredient is chloropyramine hydrochloride. The dosage of one tablet is 25 mg; there are no other dosages of Suprastin.

The drug not only has antiallergic properties, but also eliminates itching.

The medication is available in tablet form and in the form of injection solutions. The tablets have antispasmodic, anti-edematous and anti-inflammatory effects.

Taking tablets is indicated for the following diseases:

• conjunctivitis and rhinitis caused by pollen and pet dander;
• use of chemical substances;
• acute or chronic eczema;
• insect bites;
• auxiliary effect against viral and bacterial infections.

Injections are administered both intravenously and intramuscularly when acute development pathology. The injection is given only by a medical professional.

Suprastin replaces Diphenhydramine in lytic mixture.

Medical properties:

1. Pharmacological properties– blocker of histamine and m-choline blocking receptors.
2. Pharmacokinetics– metabolized in the liver and excreted in the urine.
3. Overdose accompanied by symptoms such as hallucinations, seizures, ataxia and loss of coordination.

You can purchase Suprastin at any pharmacy chain. The drug is not a prescription and is included in the list of vital drugs. average price for Suprastin in tablet form 130 - 180 rubles.

Tavegil is an antihistamine. Distinctive feature lies in the duration of the effect and the absence of sedation.

Tavegil is a drug that appeared recently, which is a derivative of Clemastine. The active ingredient is clemastine hydroforumate.

Available in three forms - tablets, syrups and solutions for injection.

Despite the fact that the product is young, Tavegil has proven itself with positive side. The drug has wide range actions and is used in the following immune processes:

• weeping eczema;
• and contact dermatitis;
• angioedema;
• hives;
• post-vaccination allergic reactions;
• as preparation before vaccination.

Unlike Suprastin, Tavegil is not used in a lytic mixture. Since the drug contains lactose, Tavegil should be limited to persons suffering from galactose deficiency and glucose-galactose malabsorption.

Medical characteristics:

• active ingredient per tablet contains 1.34 mg;
• pharmacological action – H1 receptor blocker, prevents the development of smooth muscle contraction;
• pharmacokinetics - absorbed from the gastrointestinal tract, excreted in urine and in small quantities in breast milk;
• Using the drug in excess of the norm by 300 times leads to a decrease in the ability to conceive.

The drug is over-the-counter, the cost is from 200 to 250 rubles for 10 tablets.

Suprastin and Tavegil - who is stronger

Having the same result, first-generation antihistamines differ from each other not only in the active substance, but also in a number of other differences.

The differences between the drugs are presented in the table below.

When choosing between two antihistamines, you should consult your doctor. It is the specialist who will select not only medicinal product, but will also write correct scheme treatment to avoid side effects and overdose.

Features of admission in childhood

Children's age is a limitation in the techniques of many medical supplies, including antihistamines.

Features of the reception are presented in the table.

Every year the number of people susceptible to allergies is growing. The need for special antihistamines is increasing. One of the most famous and widespread antiallergic drugs is Suprastin. His high efficiency and quite low price provide high demand. Most people prefer it as a time-tested drug. But are there others more modern analogues Suprastina? What can replace this remedy?

Replacing Suprastin: why and why?

Suprastin is a first generation antihistamine produced in Hungary. Main active ingredient- chloropyramine.

Indications for use are various shapes allergies: urticaria, itching, seasonal rhinitis, conjunctivitis, dermatitis, eczema, Quincke's edema, food allergy or allergies from insect bites. In addition to its main use, it is often used for general relief of the patient’s condition.

The sedative property of Suprastin is its main disadvantage - it actively affects the central nervous system and can cause side effects such as drowsiness, dizziness, and general fatigue. Thus, driving a car or being active work activity sometimes turn out to be simply impossible. Unpleasant side reactions make you want to learn more about Suprastin and its analogues.

So, what can replace Suprastin? The main analogs of Suprastin come in tablets, but some of them are also available in the form of syrup and special solutions. Below is a list of possible remedies.

Diazolin

Diazolin is a cheap and popular analogue of Suprastin, which has an antiallergic effect and reduces swelling of the mucous membranes. Does not have a strong effect hypnotic effect, penetrating into the central nervous system only slightly. It has mild anesthetic properties. Is used for combination treatment bronchial asthma. Unlike its predecessor, it does not help with treatment viral diseases. It is not a direct analogue of Suprastin and contains another active ingredient.

Basics active substance: mebhydrolin.

Indications for use:

• seasonal allergies;
• itching from insect bites;
• hay fever;
• eczema;
• conjunctivitis.

Side effects:

• may lead to dysfunction gastrointestinal tract;
• from the central nervous system may cause: dizziness, decreased reaction speed, drowsiness or hyperactivity;
• Often the use is accompanied by dry mouth.

Contraindicated for children under 3 years of age, people with diseases of the gastrointestinal tract, and women during pregnancy and lactation.

The price of the drug varies from 55–80 rubles.

Chloropyramine

Chloropyramine – inexpensive drug, blocking histamine receptors. Has sedative properties and mild antispasmodic effect. The effect occurs after 1–2 hours, the duration of the effect is 4–6 hours. In small doses, it can be used in children from 1 month.
Main active substance: chloropyramine.

When to use:

• dermatological diseases: eczema, dermatoses, contact dermatitis, itchy skin;
• allergic reactions: seasonal allergies, hay fever, conjunctivitis, urticaria.

Since chloropyramine is a direct analogue of Suprastin, it has the same side effects:

• drowsiness;
• dizziness;
• dry mouth;
• tachycardia;
• difficulty urinating.

Contraindications are:

• pregnancy;
• lactation;
• bronchial asthma.

Release form: tablets and solution for injection.

Subrestin

Subrestin – antihistamine sedative. It has antiallergic, antiemetic and antispasmodic effects. Approved for use in children, in small dosages starting from 1 month.

Basic active ingredient: chloropyramine.

Side effects and contraindications are the same as for Suprastin.

Approximate price: 115 rub.

Tavegil

Tavegil is an antiallergic drug, a modern competitor to Suprastin. Fights allergies without causing a calming effect. Reduces swelling, itching and has anesthetic properties. Can be prescribed to children from 6 years of age.

The main active substance of Tavegil: clemastine.

Indications for use:

• skin diseases: eczema, dermatosis, contact dermatitis;
• reactions to insect bites and medications;
• hay fever;
• anaphylactic shock;
• allergic swelling;
• serum sickness;
• prevention of allergic diseases.

Side effects:

• dry mouth;
• nausea, dizziness, headache;
• hearing and visual impairment;
• breathing problems;
• difficulty urinating;
• cardiopalmus.

Tablets and injections are available commercially. The cost of the drug depends on the packaging; for 10 tablets the approximate price is 150 rubles.

Loratadine

Loratadine belongs to the second generation of antihistamines. It has a rapid and prolonged effect, with no sedative effect. Has virtually no effect on the central nervous system. Adverse reactions are rare: dry mouth or vomiting. Can be used by children from 2 years of age. Do not use during pregnancy or breastfeeding, with caution in case of liver failure.

Basics active substance: loratadine.

Indications for use:

• allergic reactions of various origins;
• dermatological diseases: skin itching, eczema, dermatoses.

With enormous potential, this drug is cheaper than many other drugs: from 35–50 rubles.

Tsetrin

Cetrin is a second generation antihistamine. Reduces the severity of allergic reactions and has an anti-inflammatory effect. Does not affect the functioning of the central nervous system, but its effectiveness is lower than that of Suprastin. Cetrin is prescribed by a doctor as prophylactic for the treatment of allergies. It can prevent the risk of developing allergic reactions. Suitable for children over 6 years old. Available in syrup and tablets.

Active ingredient: cetirizine.

Main indications for use:

• seasonal and year-round rhinitis;
• swelling;
• hives;
• skin allergic diseases.

The cost of packing tablets is 10 pcs. - 155–165 rub. syrup price - 120 rub.

Quantity available funds the similar spectrum of action is quite large. A cheap or expensive analogue of Suprastin may have the same side effects, while obviously differing in price. Expensive drugs- not necessarily always good. And direct cheap analogues contain the same main component as Suprastin, so you shouldn’t be afraid of them. You need to choose, taking into account specific individual needs, characteristics of the body and doctor’s recommendations.

A comparative article of two first-generation allergy drugs, which will answer which is better - Suprastin or Tavegil for various diseases. Features of the use of each drug.

An allergic reaction is an immune response that results in the production of an excess amount of the substance histamine in the body, which leads to the development of allergy symptoms. Both Tavegil and Suprastin act on the principle of blocking free histamine, which in turn helps relieve symptoms of hypersensitivity, but nothing more.

They cannot influence the cause of the allergy in any way. Both drugs belong to the first (with pronounced sedative effect) generation of antihistamines. It turns out that the drugs are interchangeable? Not everything is so simple, the issue should be understood in more detail.

What is the difference between Suprastin and Tavegil - comparison table

Brief instructions for use of drugs

Below we will consider the basic rules for taking medications.

Blocks the production of histamine and increases cell resistance to its effects.

1. In tablet form. Adult patients take 1 t. 2 times a day, children 6-12 years old - half as much.
2. In solution form. Adults - 1 ampoule 2 times a day. Children over one year old - at the rate of 0.025 mg per kilogram of weight.

Side effects

• Reactions from the nervous system (cephalalgia, dizziness, lethargy, decreased reaction speed and drowsiness),
• reactions from the gastrointestinal tract (dyspepsia),
• shortness of breath, suffocation, increased blood pressure.

special instructions

Not recommended for persons of character professional activity which is associated with the need high speed reactions, people with liver pathologies. If a mild immune reaction is observed, preference is given to the tablet form of release.

Suprastin

The method of action on the body is identical to Tavegil.

Pills:

• Adults - 1 t. 3-4 rubles/day,
• children from 6 to 12 years old - half a tablet 3 times a day,
• children from one to six years - half a tablet 2 times a day.
• At the age of one month to one year - a quarter of a tablet twice a day.

IM solution (strictly under the supervision of a physician):

• Adults - 1-2 ml;
• 6 - 14 years - 0.5-1 ml;
• 1 - 6 years - 0.5 ml;
• up to 1 year - 0.25 ml.

Side effects

• Dyspepsia, psychomotor agitation,
• often - drowsiness, decreased blood pressure,
• side effects are also possible excretory system, musculoskeletal system, hematopoietic system, etc.

special instructions

Use with caution in diseases of the gastrointestinal tract, including the liver and gall bladder, it causes severe drowsiness and has a sedative effect, therefore it is categorically not suitable for some categories of patients.

Tavegil or Suprastin - which is better for specific problems

Now let's look at the features of using drugs for various diseases.

Chicken pox

Chickenpox is herpetic lesion thickness of the dermal layer, during which painful papules develop on the surface of the skin. They itch painfully due to irritation of receptors located in the epidermis.

To relieve itching, “heavy artillery” is not required. Suprastin is enough.

For allergies

Depends on the nature of the process. At emergency conditions(Quincke's edema, anaphylactic shock) the use of either of the two drugs in the form of an injection solution is indicated.

For long-term relief of mild allergy symptoms, Tavegil is more suitable, because its effect lasts up to 12 hours, which is longer than Suprastin.

How to take Tavegil and Suprastin for allergies?

According to dosage. Tavegil - one tablet twice a day, children are prescribed half the dosage. Suprastin - a tablet or half a tablet (for children under six years old) twice a day. For patients under one year of age, take a quarter of a tablet twice a day.

For psoriasis

Psoriasis affects the deep layers of the skin, causing a secondary allergic reaction. Since the process can be described as complex and difficult, therefore, in the composition complex treatment antihistamines are used.

Second generation drugs have the best effect.

In the case of using first-generation antihypertensive drugs, the effectiveness will be approximately the same, but the effect of Tavegil is longer.

Other diseases

During breastfeeding and pregnancy

The issue is resolved individually with the attending physician during a face-to-face consultation.

For babies

Only Suprastin is suitable.

Brief summary

Which is better - Tavegil or Suprastin? To summarize, we can draw the following conclusions:

• Both drugs are quite effective for the treatment of acute pathologies, both act in the same ways.
• Both drugs are not suitable for use in the acute phase of the asthmatic process.
• Suprastin is suitable for early treatment young patients: it is acceptable to take a pharmaceutical drug from the age of one month. Tavegil is prescribed from one year of age.
• Tavegil has a less sedative effect than Suprastin.
• Tavegil has a prolonged effect: its effect lasts up to 8-12 hours.
• Both drugs are not intended for long-term use. The maximum period is a week. IN exceptional cases in consultation with the treating specialist, it is permissible to use Tavegil for almost three weeks.
• Both drugs give quick effect(10-30 minutes).

Is it possible to take Tavegil and Suprastin together?

There is no point in this. Therapeutic effect will not become stronger, an overdose may develop.

Cheap analogues of drugs:

• Diazolin.
• Diphenhydramine.

Allergy medications, such as Tavegil and Suprastin, despite the same generation and similar therapeutic effect, differ in quite a lot. However, choose your own pharmaceutical not worth it. The choice of treatment is the prerogative of the doctor. “Amateur action” with a high degree of probability will not lead to the desired results and the situation may worsen.

As soon as a person experiences an allergic relapse to any components or agents, immediately after therapy the question arises: “What Tavegil is better or Suprastin? Each of these medicines is not only excellent in its characteristics and components in its composition, but also has common pharmacological properties. Each of the drugs can cause adverse reaction in each individual case. There are some incompatibilities of the components with the composition of other drugs. Therefore, when self-medicating, you should not prescribe the dosage of antihistamines to yourself.

Which is better Tavegil or Suprastin - description of drugs

To better understand what effect Suprastin has on children and adults, and how Tavegil can affect, you should first study the main characteristics of both drugs.

Table 1. Review of two antiallergic drugs “Tavegil” and “Suprastin”

What properties do the two drugs have in common?

When you need to find the answer to the question: “Which is better, Tavegil or Suprastin?”, then it will not hurt to know them general properties, is it true that they are analogues of each other. Experts say that these two medications can replace one or the other in therapy to eliminate an allergic reaction. But they are not direct analogues of each other.

Table 2. General Tavegil and Suprastin

How do Tavegil and Suprastin differ from each other?

Suprastin has been around for a long time, compared to Tavegil. It was created 80 years ago (in 1937). For such long period The pharmaceutical industry has developed and commercialized more than one antihistamine. But Suprastin is still used effectively.

Table 3. Miscellaneous Tavegil and Suprastin

Indications and contraindications for use

Both medications also have their own indications and contraindications, although they overlap with each other.

Table 4. When to use and when not to use Tavegil or Suprastin

Instructions for use

Before use, you need to understand whether Tavegil or Suprastin is better for allergies in terms of natural elimination from the body. In the liver, clemastine is converted into metabolites if Tavegil is taken. They are removed by the liver by 45-65% from the body, the rest is removed by the urinary system. Suprastin is excreted more fully and quickly, especially in children under 5-6 years of age.

Good to know: It is important that medications not only have a healing effect, but are also excreted well from the body. That is why dosages and a certain frequency of administration are prescribed.

Table 5. Instructions for use of Tavegil and Suprastin

Average prices

If you are looking for answers to the question: “Which is better Tavegil or Suprastin?” V price category search, then Suprastin tablets can be found cheaper than Tavegil. The same applies to injection ampoules. Suprastin syrup is not produced. But there are powders that are approximately the same in price as the cost of tablets. The manufacturers of both drugs are different. Russian companies, as well as enterprises operating in the CIS countries.

Table 6. Approximate prices in Russia

It is no coincidence that Tavegil and Suprastin are in greatest demand among doctors and patients. You can also add an antiallergic drug such as Claritin to them. Their effectiveness lies in the fact that they can relieve allergy symptoms as quickly as possible, preventing swelling, nasal congestion or rash from developing.

Another reason for its popularity is the availability of some drugs for use at any age. Children, almost from birth, are allowed to be given Suprastin, for example. Tavegil and Claritin also relieve spasms and swelling no worse when the disease shows its allergenic nature.