Antibiotics cephalosporins: names of cephalosporin drugs. Antibiotics cephalosporins of the latest generation 3rd generation cephalosporins in tablets and alcohol

Pharmacists around the world work every day to improve antibacterial drugs. This is due to the fact that pathogenic bacteria can develop immunity to medications. The most used today are 3rd generation cephalosporins. Antibiotics from this series have increased activity and can be used in the fight against the most complex infections.

Cephalosporins in tablets

Against streptococci and pneumococci, it is 3rd generation cephalosporins (in tablets or other dosage form) that have the highest activity. In addition, medications in this group affect gram-negative organisms and enterobacteria. But in the fight against staphylococci, cephalosporins are practically not used. The tablets have a fairly broad spectrum of action. They are used to treat the genitourinary system, respiratory system and gastrointestinal tract.

3rd generation cephalosporins are synthetic antibiotics. They have an improved molecular structure. Thanks to this, there are practically no side effects from the use of tablets. After an illness, the immune system works in full force, and interferon in the body is produced in normal quantities. In addition, cephalosporins have virtually no effect on intestinal function. Troubles such as dysbiosis and constipation are excluded. Tablets are not suitable only for people with individual intolerance to certain components.

Medicine "Pancef"

The drug is presented in the form of film-coated tablets. The mechanism of action is based on disruption of the synthesis of the cell wall of pathogenic microorganisms. The drug "Pancef" is used to treat diseases caused by aerobic and anaerobic microorganisms. Most often, tablets are used for inflammatory processes of the respiratory system. The drug is prescribed for pharyngitis, laryngitis, sore throat, sinusitis, etc. Less commonly, Pancef tablets are used to treat the urinary tract.

If we consider 3rd generation cephalosporins for children, then the drug “Pancef” is worth remembering first. After all, it can be prescribed to children older than 6 months. For babies who cannot chew, a suspension of granules is prepared. Adverse reactions practically do not occur. In rare cases, hives or slight skin itching may occur. The drug is contraindicated only during pregnancy and lactation. It should not be taken by people with sensitivity to certain elements of the drug.

Antibiotic "Suprax"

3rd generation cephalosporins are also available in pharmacies with this drug. The medicine is available in capsule form. The main active ingredient is cefixime. Auxiliary components are magnesium stearate, colloidal dioxide and carmellose calcium. Granules can be used internally or used to prepare a suspension. The mechanism of action of the drug is based on inhibition of the synthesis of the cell membrane of pathogenic bacteria. The positive effect of taking the medication occurs after 4 hours.

The drug can be prescribed to children up to one year old. The dosage is determined according to body weight. Children are prescribed 9 mg per 1 kg of weight per day. Adults, as well as children weighing over 50 kg, are given 400 mg of the drug per day. If adverse reactions occur, Suprax tablets should be replaced with another drug. A rash and itchy skin may occur on the body. Some patients experience individual intolerance to the drug, which is accompanied by dizziness and nausea. Suprax tablets should be prescribed with caution to elderly people, as well as to patients suffering from kidney disease.

Medication "Cefotaxime"

Some 3rd generation cephalosporins are used prophylactically after surgery. The drug "Cefotaxime" has a small number of side effects. Therefore, it is often used as a preventive measure. Rarely, patients experience nausea and headaches caused by individual intolerance to individual components of the drug.

Medicine "Cedex"

These are popular 3rd generation cephalosporins in tablets. The main active ingredient is ceftibutene. The excipients are sodium carboxymethyl starch, magnesium stearate, and microcrystalline cellulose. Zedex tablets have an excellent effect on microorganisms that have developed resistance to penicillins. The drug is almost completely absorbed in the stomach. Therefore, in most cases there are no side effects.

Cedex tablets are prescribed to children over 12 years of age to treat bacterial infections of the respiratory system. To achieve a good therapeutic effect, the drug is used for at least 5 days. In rare cases, the course must be repeated. Mild bacterial infections can be treated at home with Cedex. The drug can be prescribed during pregnancy. But patients who have pills are contraindicated. For patients with renal failure, the medication is prescribed in a reduced dosage.

Medicine "Spectracef"

A medicinal antibacterial agent, the main active ingredient of which is cefditoren. Additionally, croscarmellose tripolyphosphate, magnesium stearate are used, and 3rd generation cephalosporin antibiotics are used to treat infections of the respiratory system, as well as simple infections of the skin and subcutaneous tissue. Spectracef tablets do an excellent job of treating furunculosis and folliculitis.

Oral cephalosporins of the 3rd generation "Spectracef" are prescribed to patients over 12 years of age, 200 mg twice a day. In the most difficult cases, the dosage is doubled. In this case, the treatment period should not exceed 14 days. Most often, Spectracef tablets are prescribed for treatment in a hospital. Contraindications include only a severe allergic reaction to penicillins. Tablets can be prescribed to older people, as well as women during lactation.

3rd generation cephalosporins in powder form

Many patients, due to their physiological characteristics, cannot take pills. First of all, these are elderly people and preschool children. Children are most often prescribed 3rd generation cephalosporins in the form of a suspension. The price of such drugs is quite high. They are flavored, making it easier to take the antibiotic.

For older people, cephalosporins can be prescribed in the form of an injection solution. Such remedies are more effective and show good results much faster.

Medicine "Fortum"

An antibacterial drug belonging to the group of 3rd generation cephalosporins. The main active ingredient is ceftazidime. The excipients are carbon dioxide and sodium carbonate. The drug is presented in the form of a powder for preparing a solution. Most often, the antibiotic Fortum is prescribed for the treatment of severe infections in a hospital setting. The maximum daily dose is 6 g.

The drug can be prescribed to children older than two months. The dosage is determined based on body weight (30 mg per 1 kg). The antibiotic is administered three times a day. Depending on the form and complexity of the disease, the course of treatment can be 5-14 days.

The antibacterial agent "Fortum" is not prescribed to patients with renal failure. If an allergic reaction occurs, the drug is replaced. The medication can be prescribed to pregnant and lactating women. But preference should be given to more gentle treatment.

Means "Tizim"

Another broad-spectrum cephalosporin antibiotic, which is offered in pharmacies in powder form. The drug is indicated for severe infectious diseases; therapy is usually carried out in a hospital setting. The medication helps combat peritonitis and sepsis. Tizim is not used to treat mild respiratory tract infections.

The dosage of the antibacterial drug is determined individually by a specialist, based on the form and location of the infection. The daily intake for adults should not exceed 4 g. The medication can also be prescribed to babies up to one year old. In this case, the dosage is determined by the child’s body weight. Children are prescribed 30 mg per 1 kg of body weight per day. The medication can be used during pregnancy. The antibiotic "Tizim" is prescribed with caution to people with diabetes and renal failure.

This group of cephalosporins exhibits antipseudomonal activity for the first time. According to the antibacterial spectrum against gram-positive microbes, they are weaker than the drugs of the first 2 generations.

Cefotaxime (claforan). The most famous antipseudomonal cephalosporin. In addition, it can be used to treat infections caused by gram-negative pathogens such as anaerobes. The drug is prescribed 1.0 g 2 times a day intramuscularly or intravenously.

Ceftriaxone. The properties of the drug are close to claforan. Has a prolonged effect. Prescribed 1.0 g 1 time per day intramuscularly or intravenously.

Moxalactam. Practically no different from 3rd generation drugs. Prescribe 1.0 g 2 times a day intramuscularly or intravenously.

Ceftizoxime. The drug is prescribed 0.5 g intramuscularly or intravenously. Available in bottles of 0.5 g.

Oral cephalosporins 3rd generation.

Drugs of this generation have improved pharmacological characteristics. Their half-life has increased, which allows them to be prescribed 1-2 times a day. The antibacterial spectrum has expanded. Resistance to the action of b-lactamases produced by gram-negative microorganisms, with the exception of Pseudomonas aeruginosa, has increased.

Cefpodaxime. Penetrates well into the lungs and bronchi. Excreted in urine and bile. The drug is prescribed for bronchitis and pneumonia caused by atypical flora, otitis media and sinusitis. The usual dose for adults is 0.1 -0.2 g, 2 times a day. Available in tablets of 0.1 and 0.2 g.

Cefixime (cefspan) It has a wide spectrum of bactericidal action against some types of gram-positive bacteria and a number of gram-negative microorganisms. Accumulates in blood serum, urine and bile.

The drug is prescribed 0.2 g 2 times a day or 0.4 g 1 time a day.

The course of treatment is 7-10 days. Available in tablets of 0.2 and 0.4 g; in the form of a suspension – 10 mg/5 ml.

Cefprozil (cefzil). Widely used in children's practice. The main indications for prescribing the drug are otitis media, sinusitis, diseases of the upper and lower respiratory tract.

Adults are prescribed 0.25-0.5 g 1 or 2 times a day, children - at the rate of 15 mg/kg body weight. Available in tablets of 0.25 and 0.5 g, as well as in the form of a suspension - 125 or 250 mg/5ml.

Ceftibuten (cedex). Has the ability to quickly penetrate body tissues. One of the most effective cephalosporins for the treatment of chronic otitis media in children and acute sinusitis in adults.

Adults are prescribed 0.4 g once a day, children – at a rate of 9 mg/kg

body weight once a day, but not more than 0.4 g per day.

Available in capsules of 0.4 g. 5 capsules per package, as well as in powder form (7.5 g in a bottle) for preparing a suspension.

1st generation of cephalosporins.

Their spectrum of action is very wide and greater than that of previous generations. They are equally highly active against both (+) and gram(-) bacteria. They are effective in the presence of bacterial resistance to cephalosporins of other generations. Highly resistant to β-lactamases. Secondary resistance to fourth-generation drugs develops slowly. All IV generation drugs are administered only parenterally (IV or IM).

These include cefepime, cefpirome (Keyten), cefclidine, cefquin, cefosprom.

The main drug of this generation is cefepime (maxipim). Used as a reserve antibiotic in the treatment of severe hospital infections of various locations.

Carbapenems.

There are 2 generations of carbapenems known. The first generation includes: imipenem, the second generation includes meropenem.

Bactericidal preparations. They have a pronounced post-antibiotic effect. Highly active antibiotics. These are the most active antibiotics against gram(+) bacteria and bacteroids and are highly active against gram(-) (second only to fluoroquinolones.

The spectrum of their antibacterial action is ultra-wide, the widest among all antibiotics. The spectrum of antibacterial action of carbapenems is equal to 4 antibacterial drugs (for example, 3rd generation cephalosporin, aminoglycoside, metronidazole and ampicillin).

Natural resistance to carbapenems in chlamydia, mycoplasmas, mycobacterium tuberculosis, fungi, protozoa and methicillin-resistant staphylococci.

Secondary (induced) resistance of microorganisms to carbapenems develops rarely and slowly. Unlike all other β-lactam antibiotics, they are not destroyed by β-lactamases. Carbapenems are administered only parenterally (IV or IM), and drugs intended for IV administration can only be administered IV. Drugs intended for intramuscular administration can only be administered intramuscularly.

Carbapenems cannot be used with other β-lactam antibiotics (cephalosporins, penicillins, monobactams) due to antagonism.

Carbapenems are low-toxic drugs with a wide range of therapeutic effects.

Indications for use. Carbapenems are reserve antibiotics for the treatment of severe infections in patients when other antibiotics are ineffective. They are used for the following infections:

1. Intra-abdominal infection. Moreover, they can be a replacement for dual antimicrobial therapy (aminoglycoside + metronidazole)

2. Obstetric and gynecological infection.

3. Severe infections in newborns.

4. Complicated urinary infections.

5. Hospital-acquired pneumonia and lower respiratory tract infections.

6. Sepsis.

7. Infections in patients with neutropenia.

8. Meningitis. In this case, the drug of choice is meropenem, as it penetrates better into the brain and has less neurotoxicity.

Monobactams.

The entire group is represented by one synthetic β-lactam antibiotic, aztreonam (azactam).

Has a bactericidal effect. The spectrum of action is narrow. The drug affects gram(-) bacteria, including Pseudomonas aeruginosa. The spectrum of antibacterial action resembles aminoglycosides, but does not have the toxic effects of the latter. Secondary resistance to azactam develops slowly and rarely. Penetrates well into tissues, excluding the brain.

Azactam is administered intramuscularly or intravenously.

It is excreted from the body unchanged by the kidneys. In case of renal failure, the dose is reduced. Azactam is a low-toxic drug.

Azactam may be an alternative to aminoglycosides, because its toxicity is significantly lower.

It is used for sepsis, peritonitis, severe brain infection.

Related information.

Today our story is about medicines. Or rather, not about drugs in general, but about those of them that raise many questions and disputes. Of course, we will talk about antibiotics. And we will tell you about such a variety as 3rd generation cephalosporins in tablets.

Cephalosporins belong to a group of semisynthetic beta-lactam antibiotics derived from “cephalosporin C,” produced by the fungus Cephalosporium Acremonium. Chemically they are similar to penicillins. The bactericidal effect of beta-lactam antibiotics is based on inhibition of bacterial cell wall synthesis. They bind to specific cell proteins and result in an osmotically unstable cell membrane.

Traditionally, cephalosporins are classified into generations, from the first to the fifth, which correspond to the dates of release and, to some extent, their scope of action. However, it is more appropriate to distinguish such drugs according to their kinetic properties and spectrum of activity.

Oral cephalosporins, regardless of the generation to which they belong, have many common features. Let's look at them.

Pharmacokinetics

While kinetic parameters such as absorption and plasma half-life vary somewhat from one substance to another, all cephalosporins remain the same and are mostly eliminated by the kidneys. Therefore, in severe renal failure, it is recommended to reduce the dose of such drugs.

Indications for use

The main indications are the same for all oral cephalosporins. In outpatient practice, they are mainly used in the treatment of respiratory tract infections, including otitis media. These medications are also used for genitourinary infections.

Of course, the resistance of existing pathogens to certain antibiotics is important here. However, to date there is no convincing data showing that one of the oral cephalosporins is superior in practice to the other. In addition, all of their available forms are child-friendly.

Side effects

As a rule, cephalosporins are relatively safe drugs. On average, only about 10% of patients receiving oral cephalosporins reported adverse reactions. The most common ones are:

gastrointestinal symptoms, especially diarrhea;
nausea, vomiting and various abdominal symptoms;
cephalosporins can sporadically cause pseudomembranous enterocolitis;
skin reactions such as rash, urticaria, itching are observed in approximately 1% of patients;
less commonly, side effects include neurological symptoms, in particular headache, changes in hematological parameters and a slight increase in transaminases.

Allergic reactions to oral cephalosporins are rare, and only in people who are allergic to penicillin.

Like other antibiotics, 3rd and 4th generation oral cephalosporin tablets may reduce the effectiveness of oral contraceptives and vaccines. All oral cephalosporins can be prescribed to pregnant women if clearly needed.

On the one hand, third-generation cephalosporins have high stability against beta-lactamase. They also have good activity against E. coli. Also, pneumococci are usually sensitive to them. On the other hand, third-generation cephalosporins are often not very effective against staphylococci, so they are not very suitable, for example, for the treatment of skin and soft tissue infections.

The list of 3rd generation cephalosporins in tablets includes the following effective drugs:

"Cefetamet". This drug can be considered as a typical representative of third generation cephalosporins. Indications for its use, like other cephalosporins, are respiratory and urinary tract infections.

"Cefix". The product has the same antibacterial spectrum of action as Cefetamet. The drug is indicated for respiratory diseases of the throat, nose, ear, urinary tract infections and acute uncomplicated gonorrhea. According to various studies, its use is slightly more likely to cause side effects than other oral cephalosporins, in particular an increase in the incidence of diarrhea.

"Cefodox". This drug has the same antimicrobial spectrum as other third-generation cephalosporins. Indications for its use are respiratory and urinary tract infections, as well as uncomplicated gonorrhea. It should be borne in mind that anti-inflammatory drugs interfere with the absorption of the drug.

4th and 5th generation cephalosporins appeared relatively recently. A distinctive feature of the latest generations of beta-lactam antibiotics is that they are introduced into the body bypassing the digestive tract, that is, parenterally. This eliminates their interaction with intestinal microflora. That is why 5th generation cephalosporins in tablets are not currently produced.

The most widely used drugs of the newest generations include:

"Cefepime"- 4th generation cephalosporin for deep intramuscular use. If there is a threat to life, the patient is given an intravenous infusion of the drug.

"Zeftera"- bactericidal and water-soluble antibiotic of the cephalosporin series of the 5th generation. The drug is active against many microorganisms that are resistant to penicillin antibiotics. Contraindicated for persons under 18 years of age.

Oral cephalosporins of different generations are considered well-tolerated and effective drugs. A wide antibacterial spectrum of action and low risks of side effects allow their use in the treatment of various infections.

This section of the site contains information about drugs of the group - J01DD Third generation cephalosporins. Each drug is described in detail by specialists of the EUROLAB portal.

Anatomical-therapeutic-chemical classification (ATC) This is an international system for classifying medicines. The Latin name is Anatomical Therapeutic Chemical (ATC). Based on this system, all drugs are divided into groups according to their main therapeutic use. The ATC classification has a clear, hierarchical structure, which makes it easier to find the right drugs.

Each medicine has its own pharmacological action. Correctly identifying the right medications is a fundamental step for successfully treating diseases. In order to avoid undesirable consequences, before using certain medications, consult your doctor and read the instructions for use. Pay special attention to interactions with other medications, as well as conditions of use during pregnancy.

ATX J01DD Third generation cephalosporins:

Group drugs: Third generation cephalosporins

If you are interested in any other medicines and preparations, their descriptions and instructions for use, synonyms and analogues, information about the composition and form of release, indications for use and side effects, methods of use, dosages and contraindications, notes on the treatment of children with medicines, newborns and pregnant women, prices and reviews of medications, or you have any other questions and suggestions - we will definitely try to help you.

Whether you like it or not, every parent sooner or later faces the fact that their child is prescribed an antibiotic. Only mom and dad know how many tears, pain, sleepless nights and persuasion to take a pill are hidden behind this word “antibiotic”. However, whatever one may say, today they occupy one of the most important places in the life of any person, especially a child.

In this article I will talk about a group of broad-spectrum antibiotics that have proven themselves in the treatment of children, saving millions of lives every year for more than 50 years. This group of antibiotics is called cephalosporins.

I already wrote about the use of azithromycin and amoxiucillin in children in the article Antibiotics for children. Which antibiotic is best for children?

From 1964, when the first antibiotic from the cephalosporin group was obtained, until today there have been 5 generations of cephalosporins. I will tell you in detail about the use, dosages, give analogues of drug lists, and also give examples of calculating the dose of 1st, 2nd and 3rd generation cephalosporins. I will not talk about the fourth and fifth generation of cephalosporins, since the 4th generation is used only in injection form (injections), and there is no experience with the use of 5th generation cephalosporins in children.

1st generation cephalosporins

1st generation drugs act as an alternative to penicillin antibiotics. They have a good effect on bacterial diseases of the ENT organs and upper respiratory tract. The antibiotic is sensitive to streptococcal and staphylococcal flora (tonsillitis, sinusitis, tonsillitis, tracheitis, bronchitis, etc.). The only disadvantage of this generation is that first generation oral cephalosporins must be taken 3-4 times a day. If your child is older, then there will be fewer problems, but if you are very young, then certain difficulties may arise. In addition, now the entire civilized world is striving to reduce the frequency of taking medications. A single dose of the drug per day is considered ideal. Studies have shown that if a medicine must be taken 3-4 times a day, then a large percentage of patients simply do not comply with these prescriptions in full. For first-generation cephalosporins, this is, of course, a big minus, but low prices are, of course, a plus.

1st generation cephalosporins - list of drugs

Cephalexin;
Cefadroxil;
Lexin;
Ospexin;
Cefazex;
Cefazolin;
Reflin;
Cefazolin-Astrapharm;
Cefazolin-Bhfz;
Cefazolin-Darnitsa;
Cefazolin-Norton;
Cefazolin-Pharmex

This is a list of the most common 1st generation cephalosporins, which are found in the form of tablets, suspensions and injections.

For children, Cephalexin (Leksin) is prescribed at a rate of 25–50 mg/kg/day in 2–4 doses; if necessary, the daily dose can be increased to 75–100 mg/kg.

The release forms of cephalexin are in capsules of 250 and 500 mg, and in the form of a suspension of 5 ml/250 mg. An example of dose calculation for a 4 year old child weighing 20 kg. Take, for example, a moderate infection. 20 kg * at 50 mg/kg = 1000 mg/day. Divide all this by 4, it turns out that you need to take 250 mg of cephalexin 4 times a day. 5 ml/250 mg suspension or 1 capsule at a dosage of 250 mg 4 times a day.

2nd generation cephalosporins

The spectrum of action of cephalosporins of the second generation is wider than that of representatives of the first generation. Cefuroxime axetil is currently considered the main oral drug for the treatment of community-acquired respiratory infections, and it is the drug of choice for community-acquired pneumonia. 2nd generation cephalosporins have a low incidence of diarrhea when taken. Children can take from 6 months.

2nd generation cephalosporins - list of drugs for children

Zinacef;
Zinnat;
Yokel;
Abicephus;
Aksef;
Aksetin;
Auroxetil;
Bactilem;
Biofuroxime;
Euroxim;
Zocephus;
Kimacef;
Mikreks;
Spizephus;
Furoxef;
Cephur;
Cefoctam;
Cefumax;
Ephexia;
Cefuroxime-Bhfz;
Cefuroxime Kabi;
Cefuroxime-Credopharm;
Cefuroxime Mj;
Cefuroxime-Mip;
Cefuroxime-Norton;
Cefuroxime Sandoz;
Cefuroxime-Pharmex;
Cefutil.

As you can see, the list of 2nd generation cephalosporins is represented on the market by a huge number of analogues, which indicates the widespread use of these antibiotics.

The advantage of using 2nd generation cephalosporins is a reduction in the frequency of dosing to 2 times a day and a wider spectrum of action than 1st generation cephalosporins.

Release forms: tablets of 125 and 250 mg and suspensions of 5 ml/125 mg and 5 ml/250 mg.

The recommended dose of cefuroxime for children from 6 months to 2 years is 125 mg divided into 2 doses per day, from 2 to 12 years - 250 mg in 2 doses per day, for infections of the genitourinary system - 125 mg 2 times a day, over 12 years - 250–500 mg 2 times a day. Must be taken during or immediately after meals. For children who weigh less than 40 kg, a dose of 10 mg of cefuroxime per kilogram of the child's weight can be calculated, which will need to be divided into two doses.

The advantage of this group is a wider spectrum of action and half-life (it is enough to take once a day). A special feature of 3rd generation cephalosporins is their use for infections of the genitourinary system (cystitis, pyelonephritis, pyelitis, etc.). The most prominent representative of this generation among oral forms (tablets, capsules, suspensions) is cefixime (Suprax). Produced in capsules of 400 mg, 5 tablets on a blister. In syrup (suspension) 30 or 60 ml - 5 ml/100 mg. Of the injectables, the well-known and most common one is ceftriaxone. Available in powder form for injection in doses of 0.25, 05, 1 and 2 g.

3rd generation cephalosporins in tablets - list of drugs

All oral cephalosporins are presented in different release forms: tablets, syrups, suspensions, solutes. The main active ingredient is cefixime.

Suprax;
Ceforal;
Cefixime;
Cefik;
Cefix;
Flamifix;
Fixim;
Cephigo;
Fix;
Sorceph;
Loprax;
Ikzim;
Vinex;

All drugs on this list are presented in different dosages and forms of administration. The daily dose of cefixime for children from 6 months to 12 years is determined at the rate of 8 mg/kg/day in 1–2 doses; older children and adults take cefixime 400 mg 1 time per day. The duration of treatment depends on the severity of the infection and the child’s concomitant diseases.
Example of dose calculation: a 4-year-old child weighs 21 kg. This means 21*8= 168 mg per day. The result can be rounded to 170 mg. Knowing that there is a release form in the form of a syrup (suspension) of 5 ml/100 mg (5 ml of suspension contains 100 mg of cefixime), using elementary school arithmetic knowledge, we calculate that we need to take 8.5 ml. cefixime, which is equal to 170 mg per day.

3rd generation cephalosporins in ampoules (injectable cephalosporins)

Injectable cephalosporins are not entirely suitable for the topic of this article, but I could not ignore ceftriaxone, which is a bright and well-known representative of this generation of antibacterial drugs. Below I will give a list.

Ceftriaxone analogue in ampoules, domestic and imported

Avekson;
Alvobak;
Alcizon;
Auroxon;
Belcef;
Blicef;
Bresek;
Diacephus;
Denicef;
Xon;
Lendatsin;
Loraxone;
Maxon;
Medakson;
Norakson;
Oframax;
Parzeph;
Process;
Ratioceph;
Rotacef;
Rocephin;
Rumikson;
Terzef;
Torotseff;
Cefaxon;
Cephastus;
Cefgirin;
Cephogram;
Tsefodar;
Cefolife;
Cefort;
Cefotriz;
Ceftrax;
Ceftriaxone (If I write all the trade names with the combination of ceftriaxone, then my article will present one continuous list. I will list only the second parts of this combination: -Pliva, -Kabi, -Pfizer, -Bhfz, -Astropharm, -Darnitsa, -Credopharm, -Mip, -Norton, -Farmek).
Emsef;
Effectal;
Efmerin;

To be honest, I don’t even know why so many ceftriaxone analogues are registered in our country. Undoubtedly a good drug, and is widely used in the treatment of more than half of bacterial infections, however, having worked as a doctor for more than 35 years, I knew about a dozen names from this list, and used even fewer.
Dosage of the drug for children. Ceftriaxone can be used in children immediately after birth. Children over 12 years old - 1-2 g once a day or 0.5-1 g every 12 hours, the daily dose should not exceed 4 g. For newborns (up to 2 weeks) - 20-50 mg/kg/day. For infants and children under 12 years of age, the daily dose is 20-80 mg/kg. In children weighing 50 kg and above, doses of 1 to 2 g are used. A dose of more than 50 mg/kg body weight should be administered as an intravenous infusion over 30 minutes.

Sincerely, Skalitsky Alexander Igorevich