Quinic acid benefits and harms. Contraindications to the use of the component. And at the end of the large list of positive factors, we can note

Last years, taking into account the difficult environmental situation and the quality of many products, we are trying to healthy image life, take care of your health, and special attention deserves excess weight, which many struggle with, but not always successfully. In their quest to lose weight, people are ready to do anything and often undertake the most risky experiments. Some time ago, the public was stirred up by the idea that another panacea for excess weight had been found - green coffee. Indeed, green and black coffee beans contain chlorogenic acid, an ester of caffeic acid. It is chlorogenic acid that is one of the best antioxidants; it is involved in the normalization digestive processes and can prevent the appearance of excess weight. By knowing which foods contain chlorogenic acid and consuming those foods daily, you can reduce your risk of becoming overweight, but it pays to become more familiar with chlorogenic acid.

The benefits and harms of chlorogenic acid

Chlorogenic acid, what is it, is a question that interests many. First of all, this is a crystalline substance with a melting point of 210 degrees, and it is not possible to speak unequivocally about the benefits of this compound for the body, so scientists are still continuing their research, the results of which can shed light on how chlorogenic acid affects natural processes , occurring in the human body. First of all, this substance is famous for preventing the appearance of excess weight, but this depends, first of all, on the quality of the coffee itself. Chlorogenic acid also affects other vital processes:

  • Considering the fact that chlorogenic acid is good antioxidant, it can be assumed that it is capable of influencing mutagenic activity, preventing the appearance malignant tumors. It should also be assumed that the acid prevents the formation of blood clots, since dead blood bodies do not stick to the walls of blood vessels, which makes them elastic and healthy.
  • As a result, by consuming foods rich in chlorogenic acid, a person has a healthy appearance, young skin, beautiful hair And good vision. In this case, the human body is well supplied with blood and receives a sufficient amount of vital oxygen. It is also believed that a cup of green coffee can reduce arterial pressure, but this is still only an assumption. If you know where chlorogenic acid is found, you can, by consuming enough of the substance, lower your blood sugar levels, which is especially important for patients with diabetes. Chlorogenic acid is also a good preventive measure for cardiovascular diseases.
  • In addition to the above useful properties, it should be noted that chlorogenic acid has unique antibacterial and antivirus properties and promotes wound healing, softens irritation, strengthens muscle tissue and affects the condition of the skeleton. By participating in the cleansing processes of the body, chlorogenic acid, which also has a diuretic effect, helps normalize the functioning of the liver and other human organs.
  • Chlorogenic acid affects the course of pregnancy, but in this case the norms of its consumption should be coordinated with doctors so that the benefit does not turn into harm.

Do not forget that even the most beneficial substances can both help a person and harm him, and chlorogenic acid is no exception. You should not treat it as a panacea for all diseases, and especially when it comes to losing weight. Consuming a large number of substances, and by abusing caffeine, you can significantly harm your body, since the circulatory and nervous system may fall into disrepair. As a result, you can get the opposite effect - blood vessels become clogged, mental processes are disrupted, and most importantly, excess weight appears, which the person initially tried to fight. Thus, if you decide to lose weight and choose green or other coffee for this, try to move more and eat right. The benefits and harms of chlorogenic acid are a question for specialists; the main thing is not to abuse it and often seek advice from professionals.

Foods containing chlorogenic acid

No matter how many opinions exist, the benefits of chlorogenic acid in moderate doses are obvious, so it’s worth knowing what foods contain it in order to get enough of it. The main supplier of chlorogenic acid, as we have already found out, is coffee, and it is sufficient in roasted coffee beans, but green coffee still deserves special attention, which underlies the production of various biologically active additives used for weight loss. It should be noted that, taking advantage of the growing consumer demand for these active substances, buyers are often offered something that is not exactly what they would like, therefore, when starting to take such supplements, it is worth consulting with an endocrinologist and nutritionist.


In addition to coffee, other food products can become suppliers of chlorogenic acid to the human body. They do not contain as much substance as green coffee, but regular consumption of them in food can meet the body's needs. Suppliers of chlorogenic acid are artichokes and barberries; chicory, potatoes and eggplants are also rich in the substance. You can also compensate for the lack of chlorogenic acid by consuming sunflower seeds and other foods. Chlorogenic acid is found in sufficient quantities in the leaves of blueberries and sorrel, and it is also found in apples. Depending on growing conditions, apples can contain from 5 to 50% chlorogenic acid. It should be remembered that, just like coffee beans, apples contain beneficial substances, including chlorogenic acid, in the peel, so do not peel the skin, and remember that apples that have undergone long-term storage, useful substances you won't find it either.

Chlorogenic acid- an ester of caffeic acid with one of the stereoisomers of quinic acid.

Sometimes the term “chlorogenic acids” refers to all products of esterification of quinic acid with caffeic acid. Among monoesters, four isomers are possible, of which 3-caffeoylquinic (isochlorogenic), 4-caffeoylquinic and 5-caffeoylquinic acids actually occur. Chlorogenic acid is sometimes called 3-caffeoylquinic acid due to variations in the order of numbering of the carbon atoms in quinic acid.

Properties

It is colorless crystals with a melting point of 206-210 C. Easily soluble in water and ethanol, sparingly soluble in diethyl ether, insoluble in chloroform. Alkaline solution turns green in air, hence the name of the acid. The peaks of the UV spectrum are 240, 298 and 325 nm. In UV light it produces blue fluorescence.

Spreading

Widely distributed in nature, found in significant quantities in coffee beans, as well as sunflower seeds, blueberry leaves, white poplar, chicory roots. It was first discovered in 1893 by A. S. Famintsyn in sunflower seeds by a qualitative microchemical reaction in a section of the cotyledons. It is formed exclusively in plants and some microorganisms.

Receipt

Biosynthesis

Can form in plants in various ways. In particular, in tobacco and buckwheat the synthesis proceeds according to the following scheme:

Available chemical synthesis with preliminary protection of the carboxyl and hydroxyl groups of the starting components - quinic and cinnamic acids.

Biological role

Role in plants

Participates in the process of plant respiration. The role of chlorogenic acid in combination with phenoloxidase in the oxidation of amino acids, peptides and proteins was shown by A.I. Oparin in 1921. It is a regulator of plant growth processes and plays a role in ensuring plant immunity against phytopathogenic fungi and viruses. Takes part in stimulating the fertilization process fruit plants due to inhibition of the enzyme that destroys the phytohormone auxin - β-indolylacetic acid oxidase.

Pharmacological properties

Mainly due to its strong antioxidant effect. Its antioxidant activity is 27 times higher than that of the flavonoid naringenin, but inferior to ferulic and caffeic acid.

Inhibits the biosynthesis of leukotrienes by blocking lipoxygenases that oxidize arachidonic acid.

Reduces the level of malondialdehyde in the blood plasma and in low-density lipoproteins. By reducing the sensitivity of LDL to oxidation, it may reduce the risk of cardiovascular disease.

Enzymatically oxidized forms exhibit antiviral activity against herpes pathogens. Extracts rich in chlorogenic acid inhibited the expression of HIV reverse transcriptase. Active against strains of Escherichia coli and Staphylococcus aureus.

Hypoglycemic, hypocholesterolemic, hepatoprotective, and antitumor effects were noted.

It causes the taste-modifying effect of artichoke extract - if you rinse your mouth with it, within 4-5 minutes substances of different tastes are perceived as equally sweet.

Write a review of the article "Chlorogenic acid"

Notes

Literature

  • Deineka V. I., Khlebnikov V. A., Sorokopudov V. N., Anisimovich I. P.// Chemistry of plant raw materials: journal. - 2008. - No. 1. - pp. 57-61.
  • Zelepukha S.I.. - Kyiv: Naukova Dumka, 1973. - 192 p.
  • Levitsky A. P., Vertikova E. K., Selivanskaya I. A. Chlorogenic acid: biochemistry and physiology // Microbiology and biotechnology: journal. - 2010. - No. 2. - P. 6-20.
  • Chumakov S. S. ABOUT possible mechanisms stimulation of fertilization of fruit plants // Scientific journal of KubSAU: journal. - 2012. - No. 83(09).
  • Shapovalova I. E, Fedyakina Z. P.// Modern problems and ways of their solution in science, transport, production and education. - 2013.
  • Suruku B. . - 2011.

Excerpt characterizing Chlorogenic acid

Only by allowing an infinitely small unit for observation - the differential of history, that is, the homogeneous drives of people, and having achieved the art of integrating (taking the sums of these infinitesimals), can we hope to comprehend the laws of history.
The first fifteen years of the 19th century in Europe represented an extraordinary movement of millions of people. People leave their usual occupations, rush from one side of Europe to the other, rob, kill one another, triumph and despair, and the whole course of life changes for several years and represents an intensified movement, which at first increases, then weakens. What was the reason for this movement or according to what laws did it occur? - asks the human mind.
Historians, answering this question, describe to us the actions and speeches of several dozen people in one of the buildings in the city of Paris, calling these actions and speeches the word revolution; then they give detailed biography Napoleon and some persons sympathetic and hostile to him, they talk about the influence of some of these persons on others and say: this is why this movement occurred, and these are its laws.
But the human mind not only refuses to believe in this explanation, but directly says that the method of explanation is not correct, because with this explanation the weakest phenomenon is taken as the cause of the strongest. The sum of human arbitrariness made both the revolution and Napoleon, and only the sum of these arbitrarinesses tolerated them and destroyed them.
“But whenever there have been conquests, there have been conquerors; every time there were revolutions in the state, there were great people,” says history. Indeed, whenever conquerors appeared, there were wars, the human mind answers, but this does not prove that conquerors were the causes of wars and that it was possible to find the laws of war in the personal activity of one person. Every time, when I look at my watch, I see that the hand has approached ten, I hear that the gospel begins in the neighboring church, but from the fact that every time the hand comes to ten o’clock when the gospel begins, I I have no right to conclude that the position of the arrow is the reason for the movement of the bells.
Every time I see a steam locomotive moving, I hear the sound of a whistle, I see the opening of a valve and the movement of the wheels; but from this I have no right to conclude that the whistle and movement of the wheels are the causes of the movement of the locomotive.
The peasants say that a cold wind blows in late spring because the oak bud is unfurling, and indeed, every spring a cold wind blows when the oak tree is unfurling. But although the reason for the cold wind blowing when the oak tree unfurls is unknown to me, I cannot agree with the peasants that the cause of the cold wind is the unfurling of the oak bud, only because the force of the wind is beyond the influence of the bud. I see only the coincidence of those conditions that exist in every life phenomenon, and I see that, no matter how much and in what detail I observe the hand of a clock, the valve and wheels of a locomotive and the bud of an oak tree, I do not recognize the reason for the bell, the movement of the locomotive and the spring wind . To do this, I must completely change my point of observation and study the laws of the movement of steam, bells and wind. History should do the same. And attempts to do this have already been made.
To study the laws of history, we must completely change the subject of observation, leave kings, ministers and generals alone, and study the homogeneous, infinitesimal elements that lead the masses. No one can say how much it is possible for a person to achieve an understanding of the laws of history through this way; but it is obvious that on this path only lies the possibility of grasping historical laws and that on this path the human mind has not yet put one millionth of the effort that historians have put into describing the acts of various kings, generals and ministers and in presenting their considerations on the occasion of these acts .

The forces of twelve languages ​​of Europe rushed into Russia. The Russian army and population retreat, avoiding a collision, to Smolensk and from Smolensk to Borodino. The French army, with ever-increasing speed, rushes towards Moscow, towards the goal of its movement. The strength of its swiftness, approaching the target, increases, just as the speed of a falling body increases as it approaches the ground. A thousand miles away is a hungry, hostile country; There are dozens of miles ahead, separating us from the goal. Every soldier of the Napoleonic army feels this, and the invasion is approaching by itself, by sheer force of swiftness.
In the Russian army, as they retreat, the spirit of bitterness against the enemy flares up more and more: retreating back, it concentrates and grows. There is a clash near Borodino. Neither one nor the other army disintegrates, but the Russian army immediately after the collision retreats just as necessarily as a ball necessarily rolls back when it collides with another ball rushing towards it with greater speed; and just as inevitably (although having lost all its strength in the collision) the rapidly scattering ball of invasion rolls over some more space.
The Russians retreat one hundred and twenty versts - beyond Moscow, the French reach Moscow and stop there. For five weeks after this there is not a single battle. The French don't move. Like a mortally wounded animal, which, bleeding, licks its wounds, they remain in Moscow for five weeks, doing nothing, and suddenly, without any new reason, they run back: they rush onto the Kaluga road (and after the victory, since again the battlefield remained behind them at Maloyaroslavets), without entering into a single serious battle, they run even faster back to Smolensk, beyond Smolensk, beyond Vilna, beyond the Berezina and beyond .
On the evening of August 26, both Kutuzov and the entire Russian army were sure that battle of Borodino won. Kutuzov wrote to the sovereign in this way. Kutuzov ordered preparations for a new battle in order to finish off the enemy, not because he wanted to deceive anyone, but because he knew that the enemy was defeated, just as each of the participants in the battle knew it.
But that same evening and the next day, news began to arrive, one after another, about unheard-of losses, about the loss of half the army, and a new battle turned out to be physically impossible.
It was impossible to give battle when information had not yet been collected, the wounded had not been removed, shells had not been replenished, the dead had not been counted, new commanders had not been appointed to replace the dead, people had not eaten or slept.
And at the same time, immediately after the battle, the next morning, the French army (due to that rapid force of movement, now increased as if in the inverse ratio of the squares of the distances) was already advancing by itself on the Russian army. Kutuzov wanted to attack the next day, and the whole army wanted this. But in order to attack, the desire to do so is not enough; there needs to be an opportunity to do this, but this opportunity was not there. It was impossible not to retreat to one transition, then in the same way it was impossible not to retreat to another and a third transition, and finally on September 1, when the army approached Moscow, despite all the strength of the rising feeling in the ranks of the troops, the force of things demanded so that these troops march for Moscow. And the troops retreated one more, to the last crossing and gave Moscow to the enemy.
For those people who are accustomed to thinking that plans for wars and battles are drawn up by commanders in the same way as each of us, sitting in his office over a map, makes considerations about how and how he would manage such and such a battle, questions arise as to why Kutuzov didn’t do this and that when retreating, why he didn’t take up a position before Fili, why he didn’t immediately retreat to the Kaluga road, left Moscow, etc. People who are used to thinking like this forget or don’t know those inevitable conditions in which the activities of every commander in chief always take place. The activity of a commander does not have the slightest resemblance to the activity that we imagine, sitting freely in an office, analyzing some campaign on the map with a known number of troops, on both sides, and in a certain area, and starting our considerations with what someday famous moment. The commander-in-chief is never in those conditions of the beginning of some event in which we always consider the event. The commander-in-chief is always in the middle of a moving series of events, and so that never, at any moment, is he able to think through the full significance of the event taking place. An event is imperceptibly, moment by moment, cut into its meaning, and at every moment of this sequential, continuous cutting of the event, the commander-in-chief is in the center of a complex game, intrigue, worries, dependence, power, projects, advice, threats, deceptions, is constantly in the need to respond to the countless number of questions proposed to him, always contradicting one another.
Military scientists tell us very seriously that Kutuzov, much earlier than Filey, should have moved troops to the Kaluga road, that someone even proposed such a project. But before the commander-in-chief, especially in Hard time, there is not just one project, but always dozens at the same time. And each of these projects, based on strategy and tactics, contradicts one another. The commander-in-chief's job, it would seem, is only to choose one of these projects. But he cannot do this either. Events and time do not wait. He is offered, let’s say, on the 28th to go to the Kaluga road, but at this time Miloradovich’s adjutant jumps up and asks whether to start business with the French now or retreat. He needs to give orders now, this very minute. And the order to retreat takes us off the turn onto the Kaluga road. And following the adjutant, the quartermaster asks where to take the provisions, and the head of the hospitals asks where to take the wounded; and a courier from St. Petersburg brings a letter from the sovereign, not allowing the possibility of leaving Moscow, and the rival of the commander-in-chief, the one who undermines him (there are always such, and not one, but several), offers new project, diametrically opposed to the plan for access to the Kaluga road; and the forces of the commander-in-chief himself require sleep and reinforcement; and the venerable general, bypassed by a reward, comes to complain, and the inhabitants beg for protection; the officer sent to inspect the area arrives and reports the exact opposite of what the officer sent before him said; and the spy, the prisoner and the general doing reconnaissance - all describe the position of the enemy army differently. People who are accustomed to not understanding or forgetting these the necessary conditions activities of any commander-in-chief, present to us, for example, the position of the troops in Fili and at the same time assume that the commander-in-chief could completely freely resolve the issue of abandoning or defending Moscow on September 1, whereas with the position of the Russian army five miles from Moscow this issue could not have arisen . When was this issue resolved? And near Drissa, and near Smolensk, and most noticeably on the 24th near Shevardin, and on the 26th near Borodin, and on every day, hour, and minute of the retreat from Borodino to Fili.

Nowadays, more and more new ways to lose weight appear on the Internet. Some sources offer unusual exercises, others offer new substances and drugs that help in this difficult field.

One of these substances, actively introduced by manufacturers, is chlorogenic acid in diet pills or green coffee, which contain it. In the short period of time that it has been heard by those losing weight, many opinions and studies have already appeared that confirm or refute its benefits. Although it is not possible to understand the reality of this or that opinion.

A chemistry course will tell us what it is: chlorogenic acid is one of the organic acids contained in plants. Organic acids are weak in their action, therefore they do not harm the body when consumed naturally, that is, not in tablets and concentrates.

Like other organic acids, it is not capable of affecting acid-base balance and, from this point of view, safe. True, to confirm that this is indeed a fat-burning acid, it is necessary to conduct a series of experiments sponsored by non-manufacturers of this dietary supplement. There is no clear information about this acid yet: manufacturers say one thing, many independent experiments say something completely different.

Chlorogenic acid: benefits and harms

So, from everything said above, we can conclude that there is no harm from consuming such acid in plants (not tablets). Concentrated forms of this acid can have a detrimental effect on the liver because it is foreign to the body and the liver will detoxify it. Too much of it at once can lead to poisoning and you need to be careful with this.

As for the benefits, numerous studies confirm the presence of a common beneficial effects chlorogenic acid on the body. This substance is an antioxidant. This means that it helps reduce the amount free radicals oxygen in the skin, which leads to a slowdown in the aging process and general improvement the body's resistance to stress. In addition, the antimutagenic effect of acid has been proven, which will protect against the development cancer diseases. It also prevents sticking blood cells in vessels, which reduces the likelihood of blood clots and has a general positive impact on cardiovascular system. Some sources attribute antimicrobial and antibacterial effect. Of course, consuming chlorogenic acid does not guarantee the absence of all of the above problems, but it still makes a certain contribution to the general condition.

The presence of a fat-burning function has so far been confirmed only by studies of manufacturers of drugs with acid. They explain this effect by saying that acid reduces the proportion of glycogen used to replenish energy reserves, resulting in the body using fats. Here you can argue: the storage of glycogen does not stop, this means that all the carbohydrates (and without them it is impossible) that we ate turned into glycogen - this is also a kind of fat that is not used by the body. This means that with the use of chlorogenic acid, some fat reserves begin to be used and others are deposited. This is fraught with metabolic disorders, which can subsequently lead to diabetes mellitus. In addition, this entire process occurs in the liver, which also cannot but affect its functioning. Therefore, if the mechanism of action of the acid is really this, you need to be very careful with it.

According to one study, the use of chlorogenic fat-burning acid promotes weight loss of up to 10% of the initial value.

What foods contain chlorogenic acid for weight loss? The main source of this acid is considered. In its peel the concentration of the substance reaches 70%. It is also found in eggplants, apples, strawberries, potatoes, sorrel, barberries and other products that appear on our table every day. Although, its content in the latter is much lower.

(and microbes, too, by the way) came to humanity after centuries of ignorance. Today science is one of the most invested industries in the world. We have learned to synthesize biologically active ingredients, manage your own eating habits and get the most out of your food.

One of the most important components that we can get from food (or synthetically) is quinic acid. It is found in abundance in berries, fruits, and their derivatives. How is quinic acid useful and what happens to the body when it is deficient?

general characteristics

Quinic acid (C 7 H 12 O 6) is a monobasic polyhydroxyascorbic acid. This is a crystalline substance that is found in abundance in quinine bark, plants, coffee beans, berries and fruits. There is another way to extract the quinine component (in addition to biological synthesis) - hydrolysis of chlorogenic acid. The component is used in traditional/folk medicine and homeopathy.

Brief historical background

The substance was isolated by the German organic chemist Hoffmann in 1790. The scientist isolated quinic acid from the bark of the cinchona tree (a genus of plants from the madder family). Later studies were carried out that confirmed the presence in plants.

Young plant shoots contain about 14% quinic acid (based on the weight of the resulting dry raw material).

Organic compounds are found in the following products: tobacco, apples, cranberries, unprocessed coffee beans. According to scientists Kochman and Sanbur (authors of “Isolation of Quinic Acid from Fruits”), quinic acid is most easily obtained from fruit and berry fruits. The approval is based on the ability of both the organic and synthetic components to dissolve under the influence of lead compounds.

Useful properties of the substance

After research confirming beneficial effect quinic acid per person, among adherents healthy eating a real excitement began, which subsided over time, and then simply came down to zero. What really happened?

Indeed, the component is capable of normalizing temperature human body(movement to normal occurs from both excessively low and high performance), which is so important for infectious or bacteriological diseases. Instead of stuffing yourself with pills, you can try eating quince, grapes or drinking real black. If you supply the body with the required concentration of the substance, the temperature will actually stabilize.

This effect is observed with one-time symptoms that are not associated with serious diseases, but are provoked, for example, by the weather, problems at work, or the first stage of a cold.

It is useful to introduce products with quinic acid during the recovery period after illness (regardless of severity, nature, age and other factors). The substance will help the body start the process of rapid regeneration, restore the balance of microflora and become a kind of “support” for depleted internal organs.

What else is quinine useful for:

  • speeds up metabolism;
  • increases salivation;
  • improves the secretion of gastric juice;
  • copes with stomach/intestinal disorders and others unpleasant pathologies abdominal cavity;
  • relieves headaches/migraines;
  • restores and promotes normal functioning of the nervous system;
  • helps remove the symptoms and root cause of gout/fever;
  • normalizes the level (removes excess from the body, reduces the level of harmful fats in the blood);
  • enhances the effect of medications when radiation sickness and malaria.

All organic acids (including quinic acid) have a beneficial effect on the level of digestibility. The body will absorb better and faster nutrients, which will have a beneficial effect on skin condition, energy metabolism and general health.

Interaction with other chemical components

Interacts with caffeic acid, resulting in the formation of chlorogenic acid. The substance has a pronounced antioxidant effect, oxidizes arachidonic acid, reduces the level harmful components in blood plasma and reduces the risk of heart/vascular diseases. Also, chlorogenic acid acts as a kind of protector against the human papillomavirus, coli And Staphylococcus aureus.

When interacting with alkaline foods, it changes structure and turns into quinic acid salts (in this process, the formation of calcium salt). After contact with oxygen, the substance breaks down into 3 components: and, quinone.

Contraindications, shortages and side effects

A lack of quinic acid in the body leads to noticeable weakness, decreased performance and the formation of symptoms similar to severe food poisoning. Also, an excess of the substance is fraught with loss of coordination, dizziness, and frequent uncontrollable fainting. The exact opposite effect of excessive concentration of quinic acid is overexcitation. The person does not feel the need to eat, drink or sleep. Noticeably a sharp decline brain activity. After the phase of active wakefulness, a long loss of strength occurs and a decrease in all indicators that were previously off scale.

People with poor health ( genetic pathologies, treatment period serious illnesses, temporary decrease in immunity) may be affected by quinic acid. The substance can cause hearing loss and visual impairment. In the worst case scenario, drinking acid will cause cardiac arrest.

  • food consumption ( balanced diet minimizes the risk of deficiency or excess of various substances);
  • fatty subcutaneous layer (helps reduce acid levels).

Quinic acid and body beauty

Normal concentrations of the substance help normalize blood levels. If there is less glucose, then the body begins to use subcutaneous fat to ensure energy metabolism. The result is a reduction in fat (even in the most problematic areas) and gradual weight loss.

Weight and body fat will decrease methodically. It is impossible to burn a certain fat at a certain point in the body. Volumes will be lost in the same quantity and at the same pace.

Quality of life and human health directly depends on weight. Extra body fat indicate health problems. Quinic acid will partially help cope with this problem, but get real result only possible through rational nutrition and physical activity.

Consumption of quinic acid from organic products (fruits and berries) can practically not harm the body. Dosage and individual contraindications must be observed to avoid adverse effects. Synthetic acid, which is produced on an industrial scale, must be consumed with caution. Before taking it, undergo diagnostics and consult with a doctor so as not to harm your own beauty and health.

Interaction with the human body

The daily dose of the substance is 250 milligrams. This indicator is calculated for healthy person with the optimal percentage muscle tissue and fat. If the body mass index differs from normal (in any direction), then the amount of substance consumed must be adjusted. People who suffer from overweight 500 milligrams of quinic acid will be enough, for people with a minimum percentage of fat - 150.

For any deviations from the norm, you should consult a doctor. Find out the cause of abnormal weight, eliminate it and discuss with your doctor the need to consume some organic components and completely/partially avoid others.

To cover daily norm organic component It is enough to eat 1-2 handfuls of seasonal berries and a few fresh fruits. The body especially needs quinic acid when:

  • disorders of the psycho-emotional state, depression, nervous disorder;
  • elevated body temperature (if tests and examination do not find another root cause of abnormal temperature);
  • a certain list of diseases gastrointestinal tract regardless of the stage and cause of development (regulated by the treating doctor).

Contraindications to the use of the component

There are only 2 contraindications: allergic reaction on the substance and the presence of abdominal diseases.

Why is quinic acid desirable for some gastrointestinal pathologies, but prohibited for others? It depends on the nature of the disease, its stage and general condition patient. Each person’s body is unique, therefore it forms individual preferences and requests (including for chemical compounds). After examination, diagnosis, and therapeutic manipulations, the attending doctor receives full picture the needs of the individual patient's body. At serious pathologies The gastrointestinal tract at the acute stage excludes most foods containing quinic acid from the diet. They can aggravate the course of the disease and lead to disastrous consequences.

Methods for industrial extraction of the component

Modern science has 2 possible options: biological and synthetic.

Biological method

The bark is removed from the cinchona tree, then it is soaked for several days in a cold filtered container. It is important that the liquid does not contain harmful components or additional impurities, as this may affect the final result. After soaking, lime milk is added to the container. The resulting liquid is filtered and then evaporated. After simple manipulations, the liquid turns into a kind of liquid syrup. From this syrup naturally crystallized quinine-calcium salt is released. The crystals are affected, after which they change state of aggregation to liquid. Quinic acid is evaporated from the resulting liquid, placed in a special container and allowed to harden. After cooling, the substance returns to the state of pure crystals (without additional “unnecessary” compounds).

Lime milk (calcium hydroxide) – Chemical substance in the form of a white powder. The element performs a binding function and acts as a basis for the preparation of concrete, Bordeaux mixture (solution copper sulfate), food additives, soil fertilizers, whitewashing of premises, disinfectants oral cavity. Lime milk can also reduce water hardness.

Synthetic method

The synthetic method is simpler and faster. Organic acid is released during the hydrolysis of chlorogenic acid.

Hydrolysis is the process of decomposition of a complex substance under the influence of liquids.

During hydrolysis, we obtain synthetic quinic acid, the characteristics of which are identical to organic ones. The substance is able to dissolve in liquids. Under influence cold water the substance dissolves instantly, but dissolution in ether or hot liquid will take an indefinite amount of time. The melting point of the acid is 160°C; when heated to 220°C, the component turns into quinine.

Quinine is a white powder obtained from the bark of the cinchona tree. Used as medication. It has a pronounced bitter taste and specific smell.

Chlorogenic acid is a complex extract, or more precisely, an ester of caffeic acid with a stereoisomer of quinine acid. Sometimes this term refers to any product of esterification of quinic acid. It is generally accepted that maximum amount Chlorogenic acid is found in green coffee that is not processed or roasted.

Chlorogenic acid for weight loss: benefit or harm?

The main property that has made this acid famous is weight loss. Coffee contains large amounts of chlorogenic acid. It is found in both green coffee beans and roasted beans.
But what causes weight loss? Experts believe that carbohydrate metabolism is the main point of the application. In other words, chlorogenic acid activates the process of storing glucose, which comes in the form of glycogen (an energy source contained in the liver). As soon as we need calories, it turns back into simple glucose molecules. Fat “reserves” remain untouched, and until all the glycogen is spent, the body will not break down lipids and carbohydrates. So, excess fat is very easily stored, but getting rid of it is difficult. Chlorogenic acid converts fat into accessible view source of calories, blocks the release of glucose, forces the body to spend fats, and then carbohydrates, which promotes weight loss.
Chlorogenic acid has only been under the radar of scientists for a year, so it is difficult to talk about 100% lasting results. Useful actions:

  • reduces blood sugar levels;
  • has a positive effect on carbohydrate metabolism;
  • normalizes lipid levels;
  • provides beneficial influence on the cardiovascular system;
  • removes toxins;
  • has a mild laxative effect;
  • prevents the development of obesity.


We all know a phrase familiar from childhood: “Coffee is very harmful.” However, this statement does not coincide with reality. Scientists believe that only chronic overdose caffeine can be harmful to health, but normal doses will not lead to anything bad.

Chlorogenic acid for slimness: where it is found, how to purchase

As we have already said, the substance in maximum doses found in green coffee extract. Tablets with chlorogenic acid are sold in pharmacies and online stores. Buying them today is not a problem. Which purchasing option to choose is up to you. You can consult a pharmacist and buy a dietary supplement that contains chlorogenic acid at a pharmacy, or you can order online.

Unique chlorogenic acid in coffee

Regular roasted coffee beans contain approximately 7%. But if we take green coffee beans for example, this figure increases to 10%. IN modern dietary supplements Green coffee extract (extract) is used, where the concentration of the substance exceeds 40%. Advantages:

  • reduces blood sugar levels;
  • stabilizes insulin levels;
  • speeds up metabolism;
  • converts fat into energy.

Therefore, it is so important, before buying a treasured jar of the additive, to study its composition, to see what percentage is contained in the product. Choose dietary supplements that no longer contain any weight loss stimulants. Green coffee V pure form will not harm your health, but various impurities can negatively affect its condition.


Contraindications for use:

  • anxiety disorders;
  • IBS (irritable bowel syndrome);
  • glaucoma;
  • osteoporosis;
  • hypertension.