Why is aspirin dangerous and when is it necessary to use it? Instructions for use. What laboratory parameters should be monitored when taking Aspirin?

If we're talking about about a drug such as aspirin, then everyone can confirm its effective action. Scientifically, it is acetylsalicylic acid, which is used as an analgesic and antipyretic.

Due to its action, Aspirin has been the “Gold Standard” for many decades. So the popularity of its use is growing more and more, despite the inventions of new “brothers”, it still occupies a leading position.

For what symptoms and diseases is it taken:

• Probably no one will argue with this that one of aspirin is its antipyretic effect.
• It is also taken for dental, muscle, headache, etc. pain. But only if the pain is not critically exiled.
• In large doses it can relieve severe pain for injuries and even arthritis and others inflammatory diseases joints.
• Used to prevent cardiovascular diseases.
• It is also taken not only as a separate drug, but also combined with other medications.
• Often prescribed for gynecological diseases and even if the fetus is not carried to term during pregnancy
• There is also evidence of the positive effect of aspirin on the development of cataracts, heart attacks and thrombosis. Research has shown that it inhibits platelet function and prevents platelet aggregation.
• According to recent discoveries of Aspirin's actions on the body, a new level of its effects has been discovered, such as preventing cancer of the rectum, breast, lungs and prostate gland.

But under no circumstances should you self-medicate. Only the attending physician can prescribe it correct doses Otherwise, it can cause harm to the body.

How to take Aspirin correctly

Nothing, including aspirin, should be taken at will. Aspirin should come with instructions detailing the steps for its use. After all, the rules of use were made by various studies. And only in this way can you achieve the desired result from this drug.

Rules for using Aspirin:

• The first step is to consult a doctor to make sure that you need it for a particular disease.
• Only a doctor can prescribe the dosage of the drug. Otherwise, the body may receive more doses than necessary and will have to be treated for an overdose.
• For an adult (with fever and pain) a person should not take more than 4 aspirin tablets per day, and for children under one year old - 1 tablet, 2-4 years - 2 tablets.
• A single dose (for fever and pain) for an infant under one year old is 0.25 tablets, from 2 to 4 years old - 0.5 tablets, for an adult 1 tablet.
• The interval between doses of Aspirin should be more than 4 hours.
• Aspirin should not be taken with drinks that contain caffeine: tea, coffee, Coca-Cola, etc.
• It is best to protect the stomach with Aspirin or mineral water.

Aspirin is taken orally.

Steps to use Aspirin:

1. It should be taken into account that acetylsalicylic acid tends to irritate the gastric mucosa. Therefore, Aspirin should not be taken on an empty stomach - only after meals.
2. To reach best result Take an Aspirin tablet (capsule) with at least 1 glass of water so it will dissolve faster and begin to act.

For children, an Aspirin tablet can be pre-crushed and mixed with water and also washed down big amount water.

Side effects of Aspirin

There is not yet a single drug that is “ideal” and has no side effects, and Aspirin is also included in their composition.

Side effects with high doses of Aspirin:

• Aspirin can lead to development if you do not follow the rules of administration. This risk is especially high for those people who suffer from diseases. gastrointestinal tract.
• Also, in large doses, Aspirin can affect nervous system. Adverse reactions such as ringing, dizziness, and hearing loss may occur. But if the dose is reduced, the side effects will disappear.
• May cause hepatitis.
• Negatively affects the cardiovascular system.
• Under no circumstances should it be taken by people with blood diseases or by pregnant women in the third trimester.
• Choking and shock may occur in people with asthma and nasal polyposis.

More information about Aspirin can be found in the video.

Acetylsalicylic acid was first synthesized in the mid-19th century. For medical use, the drug was obtained in the laboratory of the German company Bayer AG in 1897. From here he began his victorious march, receiving the name “Aspirin”. The initial raw material for it was willow bark. Currently, aspirin is produced chemically. At first it was known only antipyretic effect medicines. Then, during the twentieth century, doctors discovered its new properties.

For a long time, aspirin was considered absolutely safe and was even recommended for preventive purposes. Today, doctors' opinions on this matter are divided. What are the benefits and harms of aspirin? How to use it and who should not be treated with acetylsalicylic acid? Is aspirin poisoning possible?

How does aspirin work?

Today, acetylsalicylic acid has been studied thoroughly. Accumulated great experience clinical trials. The medicine is one of the most important drugs and is included in the list of essential drugs both in Russia and according to WHO recommendations.

Such popularity is acetyl salicylic acid is explained by the fact that at a minimum side effects it has antipyretic, analgesic, anti-inflammatory, antirheumatic and antiplatelet effects. The drug belongs to the group of non-steroidal anti-inflammatory drugs. It suppresses the synthesis of thromboxanes and prostaglandins, and unlike other drugs from this group (diclofenac, ibuprofen), it does this irreversibly.

Acetylsalicylic acid is available in tablets; abroad - in powders and candles. Many drugs have been created based on salicylates. similar action. A large number of combination drugs are also produced: “Citramon”, “Askofen”, “Coficil”, “Acelysin”, “Asfen” and others.

Use of aspirin

Indications for the use of acetylsalicylic acid are:

How to take aspirin? For long-term treatment, the medicine must be prescribed by a doctor. Doses are selected individually, since the therapeutic range is quite wide.

Adult patients are prescribed from 40 mg to 1 g per dose. The daily dosage ranges from 150 mg to 8 g. Take aspirin 2-6 times a day, after meals. The tablets should be crushed and washed down with plenty of water or milk. To reduce the negative effects on the gastric mucosa when long-term treatment It is recommended to drink aspirin with alkaline mineral waters.

If the medicine is taken without the supervision of a doctor, then the duration of the course should not exceed 7 days as an analgesic and 3 days as an antipyretic.

Contraindications for use

Is aspirin harmful? Of course, like any medicine, it has its contraindications for use:

Use the medicine with caution in patients predisposed to accumulation uric acid in the body (gout). Even in small doses, aspirin delays the elimination of this substance, which can cause a gout attack.

Harm from aspirin

The medicine can also cause harm if the dosage is incorrect or as a result of interactions with other drugs. The negative effects of aspirin on the body are the following factors.

1. Salicylates attack the gastric mucosa and can cause ulceration.
2. A decrease in blood clotting under certain conditions leads to bleeding in the stomach and intestines, during surgical interventions, and during heavy menstruation.
3. Aspirin has a teratogenic effect on the developing fetus (causes deformities), therefore it is prohibited for use in pregnant women.
4. In acute viral diseases in children under 12–15 years of age, such as measles, smallpox, and influenza, treatment with aspirin may provoke hepatic encephalopathy(a disease that destroys liver and brain cells). The pathology was first described in the USA and was called Reye's syndrome.

Sometimes doctors prescribe Aspirin Cardio during pregnancy. This is usually done to reduce blood clotting or prevent heart disease. In this case, it is necessary to weigh the benefits of the medicine and possible harm from him in relation to mother and child.

It is prohibited to combine aspirin and alcohol. This combination is fraught stomach bleeding. But when hangover syndrome Aspirin is taken as a pain reliever and blood thinner; it is included in many pharmaceutical hangover remedies.

Acetylsalicylic acid can cause allergies such as bronchial asthma. The symptom complex is called the “aspirin triad” and includes bronchospasm, nasal polyps and salicylate intolerance.

The benefits of aspirin and the harm - what is more?

In the discussion on the benefits and harms of aspirin, various facts are voiced. Thus, according to studies conducted in the USA, regular appointment aspirin reduces the risk of developing:

• bowel cancer by 40%;
• prostate cancer by 10%;
• lung cancer by 30%;
• oncology of the throat and esophagus by 60%.

According to other data, in people aged 50 to 80 years, prone to heart disease, with regular use of acetylsalicylic acid, life expectancy is extended, and mortality from these diseases is 25% lower compared to the control group.

Cardiologists say that the benefits of taking aspirin for cardiovascular pathologies immeasurably greater than the possible harm. This largely applies to women during menopause, in whom the medicine improves blood circulation, reduces the likelihood of thrombosis and the risk of developing atherosclerosis.

At the same time, there are also alarming publications. According to a group of researchers in the United States, more than 16 thousand people die annually from uncontrolled use of aspirin. Finnish doctors have published data showing that taking acetylsalicylic acid doubles mortality after a cerebral hemorrhage (compared to those patients who did not take aspirin). Historian researchers have put forward a version that the high mortality rate from the Spanish flu in 1918 is associated with the massive use of aspirin in large doses (10-30 grams).

What is more in aspirin - benefit or harm? Like any medicine, acetylsalicylic acid should be used only if there are indications for its use. For a number of diseases: increased blood clotting, a tendency to thrombosis, cardiac dysfunction, taking aspirin for a long time is quite justified. The dose should be discussed with your doctor, who will also prescribe studies to monitor the side effects of the drug.

You should not take acetylsalicylic acid if there are contraindications: pregnancy, childhood up to 15 years, acute viral diseases with high temperature ulcerative lesions stomach and intestines. It is forbidden to combine the use of aspirin and alcoholic beverages, as this combination enhances the negative effect of the medicine on the gastric mucosa and can lead to ulceration and bleeding.

Aspirin is a widely used medicinal product from the group of non-steroidal anti-inflammatory drugs (NSAIDs), which has analgesic, antipyretic, antiplatelet and weak anti-inflammatory effects. Aspirin is used to normalize elevated body temperature, relieve pain syndrome various localization and origin (for example, headache, dental, joint, menstrual pain, neuralgia, etc.), and also as an anti-inflammatory agent for chronic diseases with a sluggish inflammatory process (for example, rheumatism, arthritis, myocarditis, myositis, etc.). Separately, it is worth stopping the use of Aspirin in low dosages(2 – 5 times lower dosage to relieve pain and reduce temperature) for the purpose of preventing thrombosis and embolism at a high risk of heart attacks, strokes, etc.

Types, names and forms of release of Aspirin

So, Aspirin is available in two dosage forms:
1. Tablets for oral administration;
2. Effervescent tablets for dissolution in water.

Effervescent tablets are produced under three commercial names - “Aspirin 1000”, “Aspirin Express” and “Aspirin C”, and are used to relieve pain. Aspirin effervescent tablets are currently available in two versions - containing only acetylsalicylic acid or acetylsalicylic acid + vitamin C. Accordingly, the drug with vitamin C is called "Aspirin C", and without it - simply "Aspirin 1000" and "Aspirin Express".

Tablets for oral administration are available in two varieties - for relief of pain, fever and for long-term use for the purpose of preventing thrombosis. Tablets for the relief of pain and fever are called regular Aspirin, and tablets for the prevention of thrombosis are called “Aspirin Cardio”.

Compound

• Effervescent tablets Aspirin 1000 and Aspirin Express - 500 mg of acetylsalicylic acid;
• Effervescent tablets Aspirin C – 400 mg of acetylsalicylic acid and 240 mg of vitamin C;
• Tablets for oral administration Aspirin – 500 mg;
• Aspirin Cardio tablets – 100 mg and 300 mg.

• Effervescent tablets Aspirin 1000, Aspirin Express and Aspirin C-sodium citrate, sodium carbonate, sodium bicarbonate, lemon acid;
• Tablets for oral administration Aspirin - microcrystalline cellulose, corn starch;
• Aspirin Cardio tablets - cellulose, corn starch, methacrylic acid and ethyl acrylate copolymer 1:1, polysorbate, sodium lauryl sulfate, talc, triethyl citrate.

Aspirin - recipe

In the recipe after the letters "Rp." the form of release of the drug is indicated (in this case, tablets - Tab.) and its name in quotation marks. After the name, the dosage is indicated in mg or g. After the letters "D.t.d." indicates the number of tablets that the pharmacist must give to the person upon presentation of this prescription. After the letter "S" it is indicated how the drug should be taken.

Therapeutic effect

• Analgesic effect;
• Antipyretic effect;
• Anti-inflammatory effect;
• Antiplatelet action.

In low dosages, Aspirin can reduce blood clotting and associated thrombus formation, providing an antiplatelet effect. This effect is achieved by suppressing the production of thromboxane A2, a substance that causes platelets to stick together.

In principle, in higher dosages, Aspirin also has an antiplatelet effect, but in these cases, in addition to it, the drug also has an analgesic, anti-inflammatory and antipyretic effect, which turns out to be a side effect and unnecessary when it is only necessary to suppress thrombosis.

Therefore, to achieve an isolated antiplatelet effect, Aspirin must be taken in small dosages, 100–300 mg per day. And to lower the temperature, relieve pain and reduce the inflammatory process, Aspirin is taken in higher dosages, 300 - 1000 mg per day.

Indications for use

Aspirin tablets, effervescent and for oral administration - indications for use

• Headache;
• Menstrual pain;
• Neuralgia;
• Lumbago, etc.

Aspirin effervescent tablets are indicated for use only for the relief of headaches or migraines.

It should be remembered that effervescent and regular Aspirin tablets can only relieve symptoms, but not cure the disease. Therefore, they can be used to normalize the condition in parallel with medications whose action is aimed at curing the disease.

Aspirin Cardio - indications for use

• Primary prevention of myocardial infarction in people at high risk of developing it (for example, with diabetes mellitus, hypertension, elevated level cholesterol in the blood, obesity, smoking, old age over 65 years);
• Prevention of recurrent myocardial infarction;
• Prevention of strokes;
• Prevention periodic violations cerebral circulation;
• Prevention of thromboembolism after surgical interventions on blood vessels(eg, coronary artery bypass grafting, arteriovenous bypass grafting, angioplasty, stenting and carotid endarterectomy);
• Prevention of deep vein thrombosis;
• Prevention of thromboembolism of the pulmonary artery and its branches;
• Prevention of thrombosis and thromboembolism during prolonged immobility;
• Unstable and stable angina;
• Non-atherosclerotic lesion coronary arteries(Kawasaki disease);
• Aortoarteritis (Takayasu's disease).

Instructions for use

Aspirin tablets for oral administration - instructions for use

Aspirin tablets should be taken orally after meals with plenty of water (at least 200 ml). The tablet can be swallowed whole, split into pieces, or chewed. Taking Aspirin before meals is not recommended, as this may cause discomfort and side effects from the digestive tract.

For pain of moderate and low intensity or elevated body temperature, it is recommended to take Aspirin 500–100 mg (1–2 tablets) 2–3 times a day. Maximum permissible single dosage is 1000 mg (2 tablets), and the daily dose is 3000 mg (6 tablets). For elderly people over 65 years of age, the maximum permissible daily dosage of Aspirin is 2000 mg (4 tablets). Between two consecutive doses of tablets, a break of at least 4 hours must be observed.

The duration of the course of using Aspirin for pain relief is a maximum of one week, and for reducing fever - three days. Aspirin cannot be used for longer than the specified period, since in this case the drug masks the symptoms of the disease and, thereby, does not allow it to be diagnosed in a timely manner and the necessary treatment to begin.

Aspirin effervescent tablets - instructions for use

Effervescent tablets can be taken regardless of food, since they contain substances that protect the gastric mucosa from the negative effects of acetylsalicylic acid.

If a person has a deficiency of glucose-6-phosphate dehydrogenase, taking Aspirin can provoke hemolytic anemia. Therefore, if you have this pathology, you must be careful when taking Aspirin, avoiding its use in large doses, during fever or acute infectious diseases.

The use of several painkillers in combination with Aspirin over a long period of time can provoke the development of kidney pathology. In addition, Aspirin can provoke gout attacks because it reduces the rate of excretion of uric acid from the body.

With long-term use for headaches, the development of “addiction headache” syndrome is possible, when symptoms appear immediately after discontinuation of Aspirin.

With long-term use of Aspirin, it is necessary to periodically take a general blood test, feces for occult blood and monitor liver function.

Impact on the ability to operate machinery

Overdose

Mild to moderate overdose of Aspirin is characterized by the following manifestations:

• Hearing impairment;
• Increased sweating;
• Headache;
• Confusion;
• Rapid breathing.

A severe overdose of Aspirin is manifested by the following symptoms:

• Very heat bodies;
• Respiratory depression;
• Pulmonary edema;
• Drop in blood pressure;
• Depression of the heart;
• Violation of water and electrolyte balance;
• Impaired kidney function up to failure;
• Increased or decreased blood glucose levels;
• Ketoacidosis;
• Noise in ears;
• Gastrointestinal bleeding;
• Bleeding disorders from prolongation of bleeding time to complete absence blood clot formation;
• Encephalopathy;
• CNS depression (drowsiness, confusion, coma and convulsions).

Interaction with other drugs

• Heparin and indirect anticoagulants(for example, Warfarin, Thrombostop, etc.);
• Thrombolytics (drugs that dissolve blood clots), anticoagulants (drugs to reduce blood clotting) and antiplatelet agents (drugs that prevent blood clots by preventing platelets from sticking together);
• Selective serotonin reuptake inhibitors (for example, Fluoxetine, Sertraline, Paroxetine, Citalopram, Escitalopram, etc.);
• Digoxin;
• Medicines to lower blood glucose levels (hypoglycemic agents) for oral administration;
• Valproic acid;
• Drugs from the NSAID group (Ibuprofen, Nimesulide, Diclofenac, Ketonal, Indomethacin, etc.);
• Ethanol.

It should be remembered that when taking Aspirin with anticoagulants, thrombolytics, antiplatelet agents, selective serotonin reuptake inhibitors and alcoholic beverages, the risk of bleeding and ulceration of the gastric mucosa increases. Taking Aspirin with other NSAIDs increases the risk of side effects and bleeding from the gastrointestinal tract.

In addition, Aspirin may reduce the therapeutic effect of the following medications:

• ACE inhibitors (Berlipril, Captopril, Lisinopril, Perindopril, etc.);
• Drugs that have the ability to remove uric acid from the body (Probenecid, Benzbromarone, etc.).

Aspirin for the prevention of cardiovascular diseases and cancer - video

Aspirin for children

IN developed countries In Europe and the USA, Aspirin has been prohibited for children under 15 years of age since the 80s of the last century, but in Russia there is no such ban. Therefore, the undesirability of using Aspirin in children under 15 years of age comes down solely to recommendations.

In order to reduce body temperature, relieve pain and reduce the severity of the inflammatory process for children under 15 years of age, it is recommended to use drugs containing ibuprofen or paracetamol, as they are safer.

Use during pregnancy

During the second trimester of pregnancy, Aspirin can be used only when absolutely necessary, when it is not possible to replace it with another drug, and the benefits to the mother clearly outweigh the risks to the fetus. Maximum permissible dosage Aspirin in the second trimester of pregnancy is 150 mg per day.

Aspirin passes into milk in small quantities, which does not cause any adverse reactions The child has. Therefore, when taking Aspirin in small dosages for a short period of time, there is no need to stop breastfeeding and switch the child to formula. However, if Aspirin is taken in high dosages or for a long period of time, breastfeeding should be stopped.

Aspirin for face against acne (mask with Aspirin)

• Cleanses the skin and removes blackheads;
• Reduces sebum production by skin glands;
• Tightens pores;
• Reduces inflammation on the skin;
• Prevents the formation of acne and pimples;
• Eliminates swelling;
• Eliminates acne marks;
• Exfoliates dead epidermal cells;
• Maintains skin elasticity.

Let's consider various options masks with Aspirin for various skin types:
1. For oily and very oily skin. The mask cleanses pores, soothes the skin and reduces inflammation. Grind 4 Aspirin tablets into powder and mix it with a tablespoon of water, add a teaspoon of honey and vegetable oil(olive, sunflower, etc.). Apply the resulting mixture to your face and rub in with massaging movements for 10 minutes, then rinse with warm water.
2. For normal to dry skin. The mask reduces inflammation and soothes the skin. Grind 3 Aspirin tablets and mix with a tablespoon of yogurt. Apply the finished mixture to your face, leave for 20 minutes and rinse with warm water.
3. For problematic skin with a lot of inflammation. The mask effectively reduces inflammation and prevents the appearance of new acne. To prepare the mask, several Aspirin tablets are crushed and poured with water to form a thick paste, which is applied directly to acne or pimples and left for 20 minutes, after which it is washed off.

Side effects

• Nausea;
• Vomit;
• Gastrointestinal bleeding (black stools, vomiting blood, occult blood in the stool);
• Anemia due to bleeding;
• Erosive and ulcerative lesions of the gastrointestinal tract;
• Increased activity of liver enzymes (AST, ALT, etc.).

• Dizziness;
• Noise in ears;
• Hearing impairment;
• Headache.

• Increased bleeding;
• Bleeding of various locations (nasal, gingival, uterine, etc.);
• Hemorrhagic purpura;
• Formation of hematomas.

• Skin rash and itching;
• Bronchospasm;
• Swelling of the nasal mucosa;

The benefits and harms of aspirin - video

Contraindications for use

• Ulcer of the stomach, intestines or esophagus;
• Hemorrhagic diathesis;
• Bronchial asthma provoked by taking other drugs from the NSAID group (Paracetamol, Indomethacin, Ibuprofen, Nimesulide, etc.);
• Thrombocytopenia (low platelet levels in the blood);
• Taking Methotrexate at a dosage of more than 15 mg per week;
• Severe renal or liver failure;
• Heart failure in the stage of decompensation;
• Ii III trimesters pregnancy;
• Breastfeeding period;
• Age under 15 years;
• Hypersensitivity to the components of Aspirin.

Aspirin analogues

So, analogues (in the understanding synonyms) of Aspirin in the form effervescent tablets and tablets for oral administration The following medicines are:

• Aspivatrin effervescent tablets;
• Aspinat tablets and effervescent tablets;
• Aspitrin tablets;
• Asprovit effervescent tablets;
• Acetylsalicylic acid tablets;
• Acsbirin effervescent tablets;
• Nextrim Fast tablets;
• Taspir effervescent tablets;
• Upsarin Upsa effervescent tablets;
• Fluspirin effervescent tablets.

• Aspivit effervescent tablets;
• Aspinat C effervescent tablets;
• Asprovit C effervescent tablets;
• Upsarin Upsa with vitamin C effervescent tablets.

• ASK-cardio;
• Aspicor;
• Aspinath Cardio;
• Acecardole;
• Acetylsalicylic acid Cardio;
• CardiAsk;
• Cardiopyrin;
• Thrombo Ass;
• Thrombogard;
• Thrombopol.

Aspirin - reviews

Almost all reviews of the use of Aspirin in face masks are positive (more than 95%), which is due to the excellent cosmetic effects of the drug. Women who have used Aspirin in this way note that the masks dry out the skin, eliminate inflammation, and completely remove small pimples, reduce large acne, remove blackheads and tighten pores. After a course of several masks, the skin becomes much better, cleaner and more beautiful, which, of course, appeals to women who leave positive feedback about the use of Aspirin.

More than 95% of reviews about Aspirin Cardio are also positive, which is due to a significant improvement in well-being while taking the drug, as well as normalization of heart function, which is felt not only subjectively, but is also confirmed by data from tests and examinations. In the reviews, many people note that Aspirin Cardio is safe for the stomach and well tolerated, which is also an advantage of the drug.

Paracetamol or Aspirin?

If we are talking about an adult, then to reduce the temperature it is recommended to first use Paracetamol, and if it turns out to be ineffective, then take Aspirin. It is not recommended to take Aspirin as a first-line treatment to reduce fever, since Paracetamol is safer and in many cases equally effective.

To thin the blood and as part of complex therapy for cardiovascular diseases and thrombosis, only Aspirin should be used. It is advisable to choose specialized drug Aspirin Cardio, but if it is impossible to purchase it, you can take it regular aspirin half or quarter of a tablet.

Which antipyretic is better for a child: aspirin or paracetamol - video

Joint use of Aspirin and Analgin for colds and flu

Thus, Analgin can cause anaphylactic shock or the almost complete disappearance of blood leukocytes, that is, conditions that quite often end in death. No less severe, but not as deadly, complications of taking Analgin are persistent hypothermia (low body temperature) and collapse. Due to the fairly high incidence of such side effects, Analgin has been banned for use as an antipyretic since the 60s in Europe and since the 70s in the USA. Routine use of Analgin for fever has not been recommended by WHO since 1991.

Aspirin can enhance negative effects Analgin, which makes this combination of drugs very dangerous. Therefore, if you have an elevated body temperature, you should not take Aspirin and Analgin at the same time.

Cardiomagnyl and Aspirin Cardio - what's the difference?

Aspirin and Aspirin Cardio – price

Aspirin is a drug that today has earned the recognition of millions of people. This pharmaceutical product has numerous healing properties. Influencing the human body, it has not only analgesic, but also anti-inflammatory, as well as antipyretic effects.

What are the indications for the use of aspirin?
This drug is usually used in the fight against various types pain. It can be taken both for headaches and for pain in the throat, muscles, back, and joints. Very often it is used by female representatives to combat pain during menstruation. Another indication for the use of this medication is considered to be elevated temperature body, which occurs against the background of colds or viral illnesses. Let us immediately draw the attention of all readers to the fact that this remedy can be taken only when necessary, as it tends to be addictive.
hay fever, allergies, bronchial asthma, nasal polyposis. This is explained by the fact that in the presence of these ailments, the effect of this medication can be significantly enhanced. As a result, it is quite possible to develop bronchospasm or bronchial asthma. In some cases, the development of allergic reactions was also noted.

If a child has a viral infection, then he should not be given aspirin, since this medication in this particular case can cause the development of Reine's syndrome.

How is this syndrome detected?
If it is present, the child experiences both vomiting and liver enlargement, as well as acute encephalopathy. WITH special attention This medication is prescribed to patients after operations. The fact is that it tends to have a suppressive effect directly on platelet aggregation. As a result, bleeding is quite possible, which will be very difficult to stop.

If the patient has very low excretion of uric acid, then he should also stop using aspirin. The fact is that this medication tends to further reduce this process. We should not forget that this drug, or rather its frequent or prolonged use, can lead to addiction, so it should not be used often.

ASPIRIN (also called acetylsalicylic acid) is by far the most famous analgesic, antipyretic and anti-inflammatory drug. Acetylsalicylic acid and other chemical derivatives of salicylic acid are commonly called common name- salicylates, which are one of the oldest medicines. Even in the distant past, various infusions of willow tree bark were used to treat infectious diseases, reduce pain, and lower body temperature. In 1838, scientists proved that it active substance- salicylic acid. In 1860 it was obtained synthetically for the first time.

For a long time, scientists have been searching for substances whose effectiveness is comparable to that of salicylic acid, but with less toxicity. A major discovery in the field of medicine and pharmacology was the production of acetylsalicylic acid by the French scientist C. Gerhardt. At the end of the 19th century, the German scientist F. Hofmann developed a technology for the production of aspirin. The well-known name of acetylsalicylic acid - aspirin, consists of two parts: a- (acetyl) and - spira (Spirea - Latin name plant from which salicylic acid was extracted).
This drug immediately gained wide popularity. It and substances similar to it in composition are used in the production of more than 400 drugs used for headaches and as an antipyretic. In the states, according to statistics, up to 20 tons of aspirin are consumed every year.

Aspirin is a combination drug, the effectiveness of which is achieved by the combination of the components included in the drug. It has an anti-inflammatory, antipyretic and analgesic effect, blocks platelet aggregation. Ascorbic acid stimulates redox chemical processes, carbohydrate metabolism, improves blood clotting, regenerative ability, increases the body's resistance to infectious diseases, reduces the need for certain vitamins (A, B). Satisfies the need for vitamin C in the body during fevers.
The drug is indicated:
- with feverish syndrome,
- for infectious diseases,
- for inflammatory phenomena;
- at pain of various origins (headache, toothache, migraine, neuralgia, etc.)
At internal use the drug is prescribed in the following dosages:
- Moderate dose at one-time dose for adults - 1-2 tablets 2-3 times a day, maximum daily dose - 8-10 tablets; interval at internal reception must be at least 4 hours.
- For children from 10 to 14 years old - no more than 1 tablet up to 3 times a day
- Children from 4 to 10 years old - 5-10 mg per kilogram of weight 3-4 times a day (for a child weighing up to 25 kg - a quarter of a tablet, for a child weighing more than 25 kg - half a tablet).
Aspirin is an effective, inexpensive and accessible drug (available without a prescription) that is of great importance in the treatment of various kinds diseases. The use of the drug must be carried out with strict adherence to all precautions.

Most likely, in our time you will not meet a person who has not had to take Aspirin (Acetylsalicylic acid) at least once in his life.
Aspirin is a non-steroidal anti-inflammatory drug (NSAID). It is believed that the name “Aspirin” is made up of two parts: “a” - from acetyl and “spira” - from Spiraea (this is the Latin name for the meadowsweet plant, from which salicylic acid was first chemically isolated).
For more than a century, Aspirin has been used in medicine as an antipyretic and analgesic. How often do we automatically drink an Aspirin tablet when we have fever and pain? This inexpensive and very effective drug is likely to be found in everyone’s family.

Use of Aspirin

Rules for using Aspirin

Contraindications and side effects

The next time you go to the pharmacy for that popular and familiar Aspirin, remember that self-medication can cause irreparable harm to your health. Be careful, do not be too lazy to re-read the instructions for the drug or consult a doctor.
Health to you!