The best antidepressants without prescription names. Modern antidepressants: names. Antidepressants without a prescription: names

Sooner or later modern man faces the need to purchase antidepressant drugs used in complex treatment from depressed emotional state. Antidepressants are “called upon” to serve a person to lift mood, create a positive emotional background and ultimately relief from depression.

When is a doctor's prescription required for antidepressants?

The dosage and daily regimen of medication is prescribed, of course, by the doctor. Only qualified specialist will be able to assess the true state of your psyche, accurately calculate and schedule medication doses. Compliance with the recipe when treating depression is one of the components of success in the fight against depression.

A prescription for purchasing antidepressant drugs is required only in the following cases:

• exacerbation of the disease;


• treatment of the most severe forms depression;


• at atypical form course of the disease.

The most effective in treating severe forms of depression are moclobemide, phenelzine, isocarboxazid and tranylcypromine. Phenelzine, isocarboxazid and tranylcypromine are time-tested drugs, but have been used since the 50s of the 20th century and have many side effects. Moclobemide is a new generation medicine, with a faster effect and fewer associated negative reactions.

Mild antidepressants of a new generation. What's special?

A mild form of depression can be “corrected” with the help of drugs for which pharmacies do not require a prescription. New generation antidepressants, as a rule, do not cause as much harm to the body as drugs produced in the last century. Modern “over-the-counter” antidepressants are fundamentally different from heavy medications and drugs of the older generation.

Advantages of modern antidepressants:

• faster effect on the body and elimination of depression;


• fewer side effects;


• opportunity simultaneous administration with many other medications;


• absence of significant addiction to the action of the drug.

List of mild antidepressants available without prescription (15 drugs)

Over-the-counter antidepressants are divided into: various groups according to the degree and type of their impact. Let us list the main groups and the drugs included in them.

Let's start the list by listing antidepressants stimulating action.

1. Maprotiline
Drug name: Maprotiline.
Analogs: Ludiomil, Ladiomil, Flexyx.
Indications: endogenous, involutional, psychogenic and neurotic depression, exhaustion, somatogenic, latent, menopausal depression.
Action: reducing apathy, improving mood, relieving psychomotor retardation.
Side effects: headache, lethargy, drowsiness, hearing loss, hallucinations, tachycardia, arrhythmia, vomiting, nausea, dry mouth, urticaria, swelling, weight gain, sexual disorders, stomatitis. Contraindications: epileptic disease, kidney disease, liver disease, pregnancy.

2. Prozac
Drug name: Prozac.
Analogs: Fluoxetine, Prodel, Profluzak, Fluval.
Indications: depression, bulimia nervosa, obsessive-compulsive disorders (obsessive thoughts and actions).
Action: relieves emotional overload, obsessive thoughts; will soften anorexia nervosa; eliminates premenstrual disorders; reduce anxiety and panic.
Side effects: at the beginning of treatment and with increasing doses - anxiety, drowsiness, headache, nausea. Rarely - convulsions. Possible skin rashes, pain in muscles, joints, fever
Contraindications: hypersensitivity, pregnancy, lactation.

3. Paxil
Drug name: Paxil.
Analogs: Rexetine, Adepress, Actaparoxetine, Plizil, Paroxetine hydrochloride hemihydride, Sirestill.
Indications: depression of all types in adults and children 7-17 years old.
Action: in the first weeks of use, symptoms of depression are reduced and suicidal thoughts are eliminated. Prevents relapses of depression.
Side effects: drowsiness, insomnia, loss of appetite, tachycardia, nausea, constipation, seizures, sweating.
Contraindications: hypersensitivity to paroxetine and the components of the drug. Pregnancy, lactation.

4. Deprim
Name of the drug: Deprim.
Analogues: Gelarium hypericum, Doppel-Hertz Nervotonic.
Indications: syndrome chronic fatigue, depression, emotional exhaustion, decreased ability to work.
Action: increased performance, mental and physical activity, normalization of sleep. Side effects: dry mouth, changes in performance gastrointestinal tract, fast fatiguability.
Contraindications: children under 6 years of age. Individual intolerance. It should be taken with special caution during pregnancy and lactation.

Along with medications chemical origin, in the fight against depression can be taken herbal preparations. Antidepressants of herbal etiology are herbal infusions that can be purchased at a pharmacy or prepared at home.

5. Leuzea extract
Name of the drug: Leuzea extract (Raponticum safflower).
Indications: as a complex therapy.
Action: general tonic effect, increased performance, improved mood, increased appetite.
Side effects: headache, irritability, increased blood pressure, allergic reaction, insomnia.
Contraindications: hypersensitivity, epilepsy, chronic disorders sleep, acute period infectious diseases.

6. Ginseng tincture
Name of the drug: Ginseng tincture.
Indications: hypotension, increased fatigue, overwork.
Action: increased performance, decreased fatigue, increased blood pressure.
Side effects: insomnia, headache, diarrhea, nausea, nosebleeds.
Contraindications: hypertension, children under 16 years of age, hyperfunction of the thyroid gland.

7. Schisandra tincture
Name of the drug: Schisandra tincture.
Indications: hypotension, neurasthenia, depression.
Action: stimulates the central nervous system, increases blood pressure, improves visual acuity.
Side effects: overexcitation of the central nervous and cardiovascular systems.
Contraindications: insomnia, high blood pressure, acute infectious diseases.

Let's take a closer look at the class of antidepressants sedative effect.

8. Azafen
Drug name: Azafen.
Indications: asthenodepressive syndrome, anxiety-depressive state, alcoholic depression, endogenous depression, exogenous depression, depressive states for chronic somatic diseases.
Action: elimination of anxiety and depression, manifestations of senile depression, smoothing out the negative state caused by long-term use of antipsychotics.
Side effects: nausea, vomiting, headache, dizziness.
Contraindications: hypersensitivity, myocardial infarction, ischemic disease hearts, diabetes, pregnancy, acute infectious diseases.

9. Persen
Name of the drug: Persen.
Indications: bad dream, irritability, increased nervous excitability.
Action: sedative and antispasmodic effect.
Side effects: allergic reaction. At long-term use- constipation.
Contraindications: increased sensitivity to the components of the drug, arterial hypotension. Children under 3 years old (tablets), children under 12 years old (capsules)

10. Mianserin
Drug name: Mianserin.
Indications: Depression of various origins.
Action: improves sleep, reduces nervous excitability. Side effects: drowsiness, hypokinesia, convulsions.
Contraindications: manic syndrome, pregnancy, lactation period, childhood(up to 18 years old).
Liver and kidney failure.

11. Amitriptyline
Drug name: Amitriptyline.
Indications: manic-depressive psychosis, bulimia nervosa, childhood enuresis.
Action: sedative effect, antidiuretic effect for bedwetting, analgesic effect.
Side effects: drowsiness, disorientation, excitability, hallucinations, fatigue, tachycardia, nausea, vomiting, weight gain.
Contraindications: epilepsy, intestinal obstruction, angle-closure glaucoma, pregnancy, breastfeeding.

12. Mirtazapine
Drug name: Mirtazapine.
Indications: depressive states, early awakening from sleep, loss of interest, anxious depression.
Action: restoration of the ability to have pleasure, adjustment of sleep, elimination of suicidal thoughts.
Side effects: drowsiness, dizziness, unusual dreams, tachycardia, nausea, diarrhea, decreased libido, dry mouth, increased appetite.
Contraindications: hypersensitivity to the components of the drug, epilepsy, organic brain damage.

13. Novo-passit
Name of the drug: Novo-passit.
Indications: neurasthenia, “manager” syndrome, migraine, eczema of psychological etiology.
Action: sedative, relieving nervous excitability of premenstrual and menopause, eliminating anxiety.
Side effects: allergic reactions, dizziness, drowsiness, slight decrease in muscle tone.
Contraindications: hypersensitivity to the components of the drug, children (up to 12 years), alcoholism, epilepsy, diseases, brain injuries.

14. Hawthorn tincture
Name of the drug: Hawthorn tincture.
Indications: nervousness, cardiovascular diseases, menopause, increased level cholesterol.
Action: calming effect on nervous system, normalization of heart activity, decreased excitability during menopause.
Side effects: allergic reactions, itching, urticaria.
Contraindications: pregnancy, lactation, individual intolerance, children under 12 years of age.

15. Valerian tincture
Name of the drug: Valerian tincture.
Indications: insomnia, migraine, hysteria, increased excitability, spasms of smooth muscles.
Action: calming, antispasmodic, choleretic, normalizing effect for the gastrointestinal tract.
Side effects: decreased performance, drowsiness, depression.
Contraindications: individual intolerance.

Contraindications for over-the-counter antidepressants

Antidepressants sold without a prescription have beneficial influence to eliminate neurotic conditions of various etiologies. But this does not mean at all that you can take these drugs for a very long time and without negative consequences. Many antidepressant medications that are freely available in pharmacies may have a number of contraindications. These “prohibitions” apply to almost all antidepressants: individual intolerance to the components of the drug; pregnancy; breastfeeding period; children under 18 years of age.

It must be said that each antidepressant drug, along with the contraindications listed above, may also have its own, unique to this medicine. Chemical composition And clinical use of these medications may vary. The search for new pharmacological compounds to combat depression in medical science does not stop.

First medications, leading the fight against depression, began to be prescribed to patients in the 50s of the 20th century. The drug iproniazid is at the origins of antidepressants. Currently, there are about 125 drugs with antidepressant effects in pharmacology. Be careful when choosing antidepressants!

No matter how much you would like to get rid of mental problems on your own, this is not always possible. Depression is a disease that requires consultation and treatment from a specialist. Today the most effective means in the fight against it are modern antidepressants.

Some people categorically do not accept taking medications and either do not receive treatment at all or resort to drugs traditional medicine. There are also people (mostly hypochondriacs) who look for non-existent depression and drink great amount strange pills. The vast majority of citizens simply try to take a pill (the one that someone recommended or showed in an advertisement) as soon as possible, drowning out mental discomfort.

Due to problems in the healthcare system, many are turning to self-help and self-medication, which, undoubtedly, can be a very dangerous activity. Not seeking help from a doctor when it is necessary and looking for problems when there are none is equally wrong and harmful to health.

Therefore, in the treatment of depression it is immediately necessary dot all the pointsi:

1. If observed short and shallow depression, such forms as subdepression, domestic or seasonal depression(“depressive” seasons – autumn and spring), as well as anxiety, low mood, apathy, drowsiness, decreased ability to work, you can try to cope with the problem yourself.

If psychological methods the fight against depression is ineffective, you should contact the pharmacy. There without a doctor's prescription You can buy mild antidepressants.

1. If depression heavy, deep, long lasting(lasts continuously for more than 2 weeks), accompanied by somatic problems, panic attacks, obsessive fears, thoughts about death and other complex symptoms, you should definitely and as soon as possible contact a psychiatrist or psychotherapist.

Clinical depression is treated in an inpatient or outpatient setting. The doctor prescribes medications that are not available in pharmacies without a prescription.

The sooner you take treatment for depression, the less likely that she's out of trouble psychological plan will turn into a mental illness.

What are they, modern antidepressants?

The name “antidepressant” speaks for itself - these are drugs for depression, although they are also prescribed for:

• anxiety disorders,
• panic attacks,
• phobic disorders,
• bulimia nervosa and anorexia,
• alcohol, drug addiction,
• bronchial asthma and many other diseases.

Antidepressants is a type of psychotropic medication.

Psychotropic drugs are medications that affect the mental, emotional and behavioral spheres of the individual. In addition to antidepressants, psychotropic drugs also include neuroleptics, tranquilizers, psychostimulants and other types.

How do antidepressants work? They affect neurotransmitters(biologically active chemical substances, through which they are transmitted nerve impulses in the human body), which are also called “hormones of happiness”, namely on:

• serotonin,
• norepinephrine,
• dopamine

Roughly speaking, an antidepressant blocks the collapse of “happiness hormones”, which physiologically causes the occurrence of depression. By influencing serotonin, norepinephrine and dopamine, the antidepressant fights depression.

Antidepressants were first created in 1954. To date four generations of antidepressants:

Nowadays, doctors most often prescribe drugs third generation, fourth generation antidepressants are not yet very popular and widespread.

Psychotropic drugs are available only by prescription, are used for at least six months, the dosage is determined by the attending physician and changes during the treatment process.

Over-the-counter antidepressants

Mild antidepressants are mostly natural, vegetable origin. Of course, there are also tetracyclic and SSRI drugs. Here are some of them:

• Maprotiline/Lyudiomil,
• Prozac/Fluval/Prodep/Profluzac/Fluoxetine,
• Zyban/Nousmoke/Wellbutrin,
• Paxil/Sirestill/Rexetine/Plizil/Adepress.

As of today price The range of these drugs is wide, from approximately $0.50 to $90.

Concerning herbal antidepressants , then ancient healers and healers knew about them. Until the middle of the last century, that is, until the moment when synthetic psychotropic drugs, used herbal:

• opiates,
• amphetamines,
• bromides,
• barbiturates,
• alkaloids.

Today, many of them are not used in the treatment of depression or are completely prohibited.

Modern natural antidepressants made from such plants:

• St. John's wort,
• valerian,
• motherwort,
• Melissa,
• peppermint,
• hop,
• elder,
• hawthorn,
• ginseng,
• lemongrass,
• immortelle and many others.

These herbs are used to make alcohol tinctures, extracts, and, of course, tablets. The price of such drugs is relatively low.

Perhaps the most the best remedy, the effectiveness of which in the treatment of depression has been proven by numerous clinical trials and time - St. John's wort tincture.

St. John's wort- This high grass with the little ones yellow flowers. It grows as a weed in the temperate climate of the Northern Hemisphere and is familiar to many from childhood. You don’t even have to look for a tincture from this plant in a pharmacy, but make it yourself by collecting this herb in a meadow or field.

St. John's wort is used in the manufacture of such over-the-counter antidepressants How:

• Novo-Passit,
• Negrustin,
• Deprim,
• Persen.

These and other herbal preparations also help with insomnia, irritability, stress, fatigue, low mood, loss of strength, decreased concentration and memory, physical pain unknown origin, loss of performance and also strengthen the immune system.

Although even today drugs from medicinal herbs, in the fight against severe depression without antidepressants latest generation You just can't get by!

If you yourself or someone close to you is faced with the problem of depression, these books will help:

1. Danny Penman, Mark Williams “Mindfulness. How to find harmony in our crazy world”
2. Dmitry Kovpak, Leonid Tretyak “Depression. Modern approaches to diagnosis and treatment”
3. Tatyana Trofimenko “Depression without rules”
4. Margit Dahlke, Rüdiger Dahlke “Dark Night” of the Soul. Healing from depression”
5. Charles G. Elliott, Laura L. Smith

Antidepressants - These are medications that improve mood and eliminate anxiety and irritability. Most often, doctors prescribe them for chronic stress or .

When there are disturbances in the emotional background in the body, not only the activity of the nervous system changes, but also the production of substances responsible for good mood and a calm perception of reality.

Since ancient times, plant materials (motherwort, valerian, eleutherococcus, lemongrass, etc.) have been used as agents that have a beneficial effect on the human psyche. And in the 20th century, synthesized tablets appeared that regulated the level of neurotransmitters (serotonin, norepinephrine, dopamine), substances on which a person’s emotional mood depends.

Antidepressants have become so firmly established that they are even glorified in modern show business. For example, the latest hit of the Chelyabinsk rap group “Triagrutrika” is called “Antidepressant”. And some foreign music channels annually compile their top list of antidepressant songs.

So the group name pharmacological drugs, so accurately reflects their action that it finds its application in cultural areas of human life. This appears to be related to how the drugs work and their ability to elevate mood.

Mechanism of action

The secret of our emotional life is revealed by the biochemical theory; its deterioration is based on processes that reduce the amount of nutrients in the human body.Antidepressants are able to normalize chemical metabolism in brain cells, regulate the level of serotonin, dopamine and norepinephrine, hormones responsible for a person’s good mood.

These drugs, depending on their action, can block the uptake of neurotransmitters by neurons or increase their concentration (production by the glands of the brain or adrenal glands).

Indications for use

• neuroses;
• phobias (fears);
• increased anxiety;
• chronic depression;
• prolonged stress;
• panic states;
• anerexia or bulimia;
• sexual dysfunctions;
• affective disorders;
• giving up drugs, alcohol, nicotine.

Patient reviews of taking antidepressants are varied. Sometimes when they are discontinued, symptoms or symptoms reappear in patients; also, some drugs are not used in women using a diet for weight loss, as they can contribute to excess weight gain.

Therefore, it is very important to choose suitable drug and carefully study its side effects. Only after weighing all the pros and cons at an appointment with a doctor (neurologist, psychotherapist, psychiatrist) can you go to the pharmacy to purchase an antidepressant.

Classification

1. Thymiretics , stimulate the activity of the nervous system.
2. Thymoleptics , medications with a pronounced sedative (calming) effect.
3. Indiscriminate actions (Melipramine, Amizol).
4. Electoral actions (Flunisan, Sertraline, Fluvoxamine, Maproteline, Reboxetine).
5. Monoamine oxidase inhibitors (Transamine, Autorix).
6. Selective (Coaxil, ).
7. Lungs antidepressants (Doxepin, Mianserin, Tianeptine) gently improve sleep and mood, and have a beneficial effect on a person’s perception of reality.
8. Strong antidepressants (Imipramine, Maprotiline, Amitriptyline, Paroxetine) actively and quickly eliminate the manifestations of depression, but have a number of pronounced side effects.

The most popular antidepressants without prescriptions

Names and prices:

Alcohol tinctures have a mild antidepressant effect:

• maralia root, immortelle, rhodiola rosea (relieves feelings of fatigue, apathy);
• Livezes, raise the overall tone of the body;
• ginseng, promotes vigor and activity;
• lures, stimulates performance;
• mint, valerian, motherwort, normalize sleep, relieve nervous tension.
  The average prices for these products in pharmacies range from 50 to 100 rubles.

Tricyclic antidepressants are used to treat persistent and prolonged depression.

List of drugs:

Despite the powerful effect in treatment mental disorders tricyclic drugs have a number of pronounced side effects, medical research show that because of them, more than 30% of patients stopped taking these drugs without completing the course of treatment. This prompted pharmacists to create new drugs without side effects that negatively affect the digestive, renal systems and metabolic processes in the body, as well as drugs that do not cause “withdrawal syndrome”.

New generation antidepressants (list of the best drugs) :

Before you start taking any antidepressant, it is important to know:

Video:

Today, depression affects not only adults, but also children and adolescents. Many specialist studies and a huge number of articles and books have been devoted to this disease and methods of combating it. If translated from “scientific” into ordinary language, depression is a loss of strength and desire to live. Symptoms of this disease are apathy and constant anxiety and fatigue, lethargy and gloom.

Modern pharmacology offers the latest generation of antidepressants to combat this disease. How many generations of thymoleptics (also called drugs that work against depression) exist today, what do they have in common and how do they differ from each other, what is their mechanism of action? These and other questions will be discussed in the article presented to your attention.

What are antidepressants?

Thanks to which you can relieve symptoms and even prevent depressive conditions. The main mechanism of their action is aimed at adjusting the biochemical activity of the human brain. its components constantly interact with each other through special substances - neurotransmitters. According to one theory, depressive disorders occur when the brain, due to various reasons, the level of any mediator or biogenic amine decreases significantly: dopamine, norepinephrine or serotonin. Antidepressants of the latest generation, like all previous ones, have a regulating and corrective effect on the biochemical processes of the brain by changing the concentration of one or another biogenic amine.

What are they needed for?

In addition to the fact that modern antidepressants help cope with the symptoms of depression, they are often used to get rid of the following problems:

• various pains of unknown origin;
• appetite or sleep disturbances;
• severe fatigue or loss of strength;
• nervousness or feelings of constant tension;
• attacks of nervousness or anxiety;
• problems concentrating or remembering.

Generations of antidepressants

Before considering how many generations of drugs against depression have been created to date, we need to remember that antidepressants were discovered only in the middle of the 20th century. Today, depending on the time of invention and the beginning of use in clinical practice, as well as from the action of antidepressants, it is customary to distinguish four generations of these drugs.

First generation drugs

The first generation, discovered in the 50s of the last century, is represented by cyclic tricyclic thymoleptics (TCAs). These include the following medicines: “Amitriptyline” (antidepressant, the very first one discovered) and its derivatives, as well as the drugs “Nefazodone”, “Anafranil” and “Melipramine”. These compounds block the reuptake of norepinephrine, thereby increasing its concentration. However, TCAs blocked not only norepinephrine (norepinephrine), but also all other neurotransmitters that came in their way, which led to a large number unpleasant side effects, especially such as sharp increase blood pressure and increased heart rate. Drugs in this group are quite toxic, and the likelihood of an overdose when using them is very high, which is why they are used so little in the treatment process depressive disorders Today.

In addition, the first generation includes drugs that are no longer used today and contain irreversible monoamine oxidase inhibitors (MAOIs) - Iproniazid, Tranylcypromine, Isocarboxazid. Their action is based on the suppression of activity nerve endings neurons of the brain, resulting in increased concentrations of serotonin and norepinephrine.

Second generation drugs

The second generation, unlike the first, has a more selective, but also weaker effect on neurotransmitters and the neurons themselves. It includes tetracyclic irreversible (MAO-B) and reversible (MAO-A) monoamine reuptake inhibitors, represented by drugs such as Lerivon, Ludiomil, Pyrazidol and a number of others. Due to the fact that many quite serious side effects occurred when taking them, as well as due to interaction with different drugs and unpredictability of effects, drugs in this group are used extremely rarely. It is quite difficult to find antidepressants from the group of monoamine reuptake inhibitors in pharmacies. But in some cases they are found under other trade names. So, experts say that the drug “Lyudiomil” is the same tablets “Maprotiline”, the price, manufacturer and country are just different.

Third generation

Modern researchers have found that about 30 mediators are involved in the functioning of the brain and nervous system, but only three of them are “involved” in depression: serotonin, dopamine and norepinephrine (norepinephrine). The third generation includes selective serotonin reuptake inhibitors (SSRIs), represented by the most commonly used modern antidepressants such as Zoloft, Citalopram, Prozac, Cipralex, Paroxetine, Plizil and many others. These medications do not block all mediators, but only one - serotonin. In terms of their potency, they are inferior to first-generation drugs, but they have significantly fewer side effects than any other predecessors. All SSRI drugs are very effective and should be tolerated approximately equally by patients. However, each of us has our own body individual characteristics, and it is because of them that the number and strength of side effects will vary in each specific case. Doctors say the most common unpleasant consequences Third generation medications include insomnia, dizziness, nausea and anxiety.

SSRI drugs are quite expensive. Thus, for the fairly well-known and widely used drug “Citalopram”, the price in pharmacies, depending on the brand under which it is released, can vary from 870 to 2000 rubles.

Fourth generation antidepressants

These usually include drugs from the SSRI group (selective serotonin and norepinephrine reuptake inhibitors). These are the latest generation antidepressants, such as Cymbalta, Milnacipran, Remeron, Effexor, which block the uptake of both norepinephrine and serotonin. The drugs Zyban and Wellbutrin do not interact with serotonin, but retain dopamine and norepinephrine. The development of drugs belonging to this group began only in the mid-90s of the last century, and every year more and more new drugs appear.

Doctors cannot say unequivocally that it is in this group that there is the most best antidepressant, this is basically impossible, since for the treatment of various types of depressive disorders, medications are selected individually, taking into account the health characteristics of each patient.

Popular modern thymoleptics

Knowing about the serious impact of drugs in this group on the nervous system, it is necessary to remember that all possible - both positive and negative - consequences can be predicted and mitigated only by a qualified specialist - a doctor. Taking into account all the individual characteristics and having made a diagnosis, it is the doctor who will be able to prescribe exactly those antidepressants that can best help in your particular case, with minimal side effects. If any problems arise while taking the prescribed medication, it is the attending physician who will be able to adjust or change the treatment regimen. Today, most practitioners recommend drugs from the group of drugs to patients with depressive disorders. selective inhibitors reuptake of serotonin and norepinephrine, the effective effects of which have been tested in practice. Medicines such as Milnacipran, Fluxen (Fluoxetine), Duloxetine, Velaxin (Venlafaxine) are the most typical and widely used antidepressants of the latest generation. Let's consider the most popular thymoleptics in the treatment of depressive disorders.

Medicine "Flucosetine"

This drug is one of the first representatives of the SSRI group; it combines both antidepressant and stimulant effects. The medicine "Fluxen", also known as the antidepressant "Fluoxetine", helps reduce anxiety and tension, eliminates feelings of fear and improves mood. Its most effective use, according to practicing psychotherapists, is in cases of asthenic depressive disorders with apathy, as well as depression varying degrees heaviness and obsessive states. This medicine is also used in the treatment of bulimia. The antidepressant Fluoxetine was first registered in 1974 in the USA, and in last decade it came out on top in sales in the UK, only under a different name trade name- Prozac. In Russia, this medicine is widely used, and many practicing doctors confirm that they prescribe it or its generics to patients for various depressive conditions.

The drug "Paroxetine"

This is the most powerful representative of the group of selective inhibitors of selective serotonin uptake, widely used in the treatment of anxiety states and depression. Today there are drugs active substance of which paroxetine is, there are quite a few. This and Russian drug"Adepress" from "Veropharm", the medicine "Plizil" from the Croatian company Pliva, the Hungarian tablets "Rexetine" from and many others. Regardless of the name of the drug "Paroxetine", reviews of it from both patients and doctors are mostly positive.

The drug "Wellbutrin"

Better known as "Zyban" or "NoSmoke". The active ingredient in all three drugs is bupropion hydrochloride, which increases the amount of dopamine and norepinephrine in the brain. Medicines with this active ingredient not only relieve symptoms of depression, but also help overcome emotional consequences quitting nicotine. This medication improves mood and increases performance. Reviews from those who got rid of nicotine addiction with the help of drugs such as Wellbutrin, KnowSmoke and Zyban, they talk about high efficiency these drugs during the period of smoking cessation.

Medicine "Cymbalta"

A drug of the fourth generation of antidepressants, which is an inhibitor of the reuptake of norepinephrine and serotonin, simultaneously carrying out a slight uptake of dopamine. This drug, the active ingredient of which is duloxetine, has a rather high speed of action compared to other antidepressants. According to reviews from both doctors and patients, a clear antidepressant effect appears by the end of the first - beginning of the second week of use. In addition, this drug is characterized by uniform action throughout the entire time of its use. However, there is a group of patients, according to whose reviews the effect of this medicine, if it occurs, is very weak. As already mentioned, the individual characteristics of the course biochemical reactions quite often lead to the fact that one or another medication prescribed by a doctor may not have the expected result.

What is the price?

Today it is quite difficult to talk about prices for medicines. This is due to the fact that currency market is extremely unstable, and new antidepressants for the most part come to us from foreign manufacturers, whose prices are presented in euros. That is why the table below presents the minimum and maximum prices in rubles, since it is simply impossible to average them. Some of the drugs that were received earlier are still sold at the old prices, while new ones are much more expensive.

If you carefully look at the table, you will notice that it does not contain second-generation drugs, namely MAOIs (monoamine reuptake inhibitors). It's not a mistake. The thing is that these antidepressants, which have big amount unpleasant side effects and incompatibility with many drugs, are practically not used in European countries. In the USA, the medications “Isocarboxazid”, “Ugenelzin” and “Tranylcypromine” are used quite rarely, and in our country the drug “Nialamide” is used. All of the above medications are available only under the supervision of psychiatrists.

This table clearly shows that the price for “classical” tricyclic antidepressants is significantly lower than for newer drugs from the SSRI and SSRI groups. Thus, it is not possible to talk about the high availability of effective antidepressant drugs for the majority of the population. However, your doctor can help you choose a less expensive drug with similar properties, the so-called generic.

Interaction with other drugs

Antidepressants can interact with other medications, even those that seem absolutely safe and familiar to us. The most active in this regard are tricyclic thymoanaleptics and monoamine oxidase inhibitors, but drugs from the SSRI and SSRI groups practically do not interact with other medications. In any case, if your doctor prescribes you any medications against depression, be sure to find out whether you can combine them with the use of other medications, dietary supplements, and even teas and herbal decoctions.

Strange as it may sound, many people who need to take thymoleptics due to various reasons, they ask how often you can combine the use of “hot” drinks and pills for depression. The answer to this question is quite simple: do you want to risk your mental and physical health, and maybe even life, try it! The fact is that both alcohol and antidepressants have a serious effect on the central nervous system and the brain, and such double pressure can negatively affect both the “flight control center” itself, that is, the brain, and the organs and systems subordinate to it. Whether or not it is worth combining is a decision that you and only you can make.

Instead of a conclusion

You shouldn’t think and rack your brains about which antidepressants are better and more effective. If you feel that each new day is becoming more difficult to live than the previous one, that you don’t have enough strength even for the simplest and most mundane things, contact a specialist! The doctor will be able to diagnose your disease and prescribe necessary treatment by choosing the medications that are most suitable for you. These may not only be antidepressants. The arsenal of today's medicine is quite extensive: different kinds psychotherapy, physical exercise and acupuncture, breathing practices and physiotherapeutic procedures.