Why do children need calcemin? Effect on the ability to drive a vehicle. Directions for use and doses

Calcemin is a well-known vitamin and mineral complex used for the prevention and treatment of diseases of the musculoskeletal system. Calcemin is necessary during pregnancy and lactation, as well as during intensive growth of children.

Pharmacological action of Calcemin

Calcemin contains: calcium, zinc, boron, manganese, copper, vitamin D. Calcium is included in the composition bone tissue. With its help, the body ensures normal vascular permeability, heart automaticity, interneuronal and neuromuscular conduction. Calcium plays an important role in the contraction of skeletal and smooth muscles, as well as in the process of blood clotting.

In Kalcemin, calcium is represented by carbonate and citrate salts. Calcium carbonate contains elemental calcium. Under the influence of calcium citrate, the drug is absorbed regardless of the condition gastrointestinal tract and stages of digestion, with long-term use reduces the risk of stone formation in urinary tract In addition, the activity of parathyroid hormone decreases.

Calcium is absorbed in the gastrointestinal tract and excreted through feces, sweat and urine. The speed of calcium excretion depends on the presence of calbindin in intestinal cells. The more it is, the faster calcium is removed from the body.

Reviews of Calcemin indicate that vitamin D included in the complex normalizes the absorption of calcium and promotes its participation in the construction, and necessary cases, and bone tissue regeneration. Vitamin D absorption occurs in small intestine. Then it enters the plasma of lymph and blood, and from there to the liver, adrenal glands, bones, myocardium, muscles and adipose tissue. Vitamin D is excreted through bile into the intestines, where it is again partially absorbed and then converted into inactive metabolites.

Zinc is one of the components that make up more than two hundred enzymes that take part in the synthesis of nucleic acids responsible for gene expression. In addition, these enzymes are involved in protein synthesis, cell growth and repair, and contribute to normal activity alkaline phosphatase(ALP). Absorption of zinc occurs in the intestines, and excretion occurs in the urine (from two to ten percent) and in feces (ninety percent).

Copper in Calcemin is necessary for participation in the synthesis of elastin and collagen; it reduces bone demineralization. Partial absorption occurs in the small intestine. The main part in the form of insoluble compounds is removed from the body with feces. Eighty percent of absorbed copper is excreted through bile, sixteen percent through the walls of the gastrointestinal tract, and about four percent through urine. The remaining small amount comes from sweat.

Manganese helps normalize the synthesis of glycosaminoglycans, thus helping to produce components of bone and cartilage tissue. Duplicates the calcium-sparing effect of vitamin D. Ninety-five percent is excreted in bile.

Boron in Kalcemin affects the activity of the produced thyroid gland parathyroid hormone, which, in turn, is involved in the metabolism of calcium, phosphorus, magnesium, colecalciferol, vitamin D. It is very quickly absorbed by the gastrointestinal tract, ninety percent is excreted in the urine.

Release form

Calcemin is available in the form of tablets containing 250 milligrams of elemental calcium or 500 milligrams of Calcemin Advance.

Indications for use of Calcemin

According to the instructions, Kalcemin is prescribed for the prevention of diseases of the musculoskeletal system, including osteoporosis, as well as in for preventive purposes with weakened periodontium and teeth. Insufficient intake from food essential vitamins and minerals, the drug is used to replenish them.

According to reviews, Kalcemin is useful for children during intensive growth. In addition, Calcemin is prescribed during pregnancy and breastfeeding to maintain the required level of vitamins and minerals. The drug is often taken by women during menopause.

The drug is also indicated for patients taking medications belonging to the groups of immunosuppressants and glucocorticosteroids.

Many patients who took the enhanced formulation of the drug give good feedback about Calcemin Advance. With its help, the healing of fractures improves, and the deficiency of microelements and calcium in adolescents is compensated. The drug is used both for the treatment and prevention of osteoporosis.

Directions for use and dosage

According to the instructions, Kalcemin is allowed to be taken by children aged five years and older. The drug is taken either before meals or during meals. The dose of the drug for children from five to twelve years old is one tablet once a day. Children over twelve years of age and adults are prescribed Calcemin one tablet twice a day. The duration of treatment is determined individually for each patient; the duration of taking the drug is not limited.

Calcemin Advance is approved for use in children aged twelve years and older. The dose of the drug for adults and children is one tablet twice a day with meals. It is also possible to prescribe the drug after the twentieth week of pregnancy. The dose is the same as usual - one tablet twice a day.

Sometimes the drug with increased content components are taken to increase the content of calcium and mineral salts in the body. In this case, it is recommended to take one tablet of Calcemin Advance per day.

Side effects

According to the instructions for Kalcemin side effects may occur due to overdose or hypersensitivity to the components of the drug. Nausea, vomiting, flatulence, hypercalcemia, hypercalciuria, and sometimes allergic reactions may occur.

Contraindications for use

Calcemin is prohibited when kidney stone disease, hypercalcemia, hypersensitivity, hypercalciuria. If, according to indications, the drug is needed for children under five years of age, it is prescribed under strict medical supervision.

Conditions and shelf life

Calcemin is stored in a dry, dark place, out of reach of children, at room temperature. The shelf life, subject to the above conditions, is three years.

Calcemin is a phosphorus-calcium metabolism regulator from the German pharmaceutical company Bayer AG. Preparations based on this mineral have been used in medicine since the time of Hippocrates. This macronutrient supports a number of essential functions body: structural, neuromuscular, enzyme, signaling. The problem of combating osteoporosis is no less age-related. This systemic disease bone loss, characterized by a decrease in their mineral density (BMD) and damage to tissue structures at the micro level, leads to an increase in bone fragility and an increased risk of fractures. According to statistics, more than 30% of women aged 65 years and older have had a fracture. According to experts, prevention of this disease with calcium supplements is advisable even for women whose BMD values ​​are normal. Against the background of use drug therapy the risk of bone fractures is reduced by 10% or more, and in patients with vitamin D deficiency - by 30%. Calcemin is a third-generation drug, one tablet of which contains 250 mg of elemental calcium (in the form of calcium citrate and calcium carbonate), as well as vitamin D, zinc, manganese, copper and boron. Due to such a significant concentration of calcium, the drug can be taken at any time, without being tied to meals. Calcium citrate provides high bioavailability medicine for diseases of the gastrointestinal tract that impair absorption, and also significantly reduces the risk of urolithiasis with prolonged pharmacotherapy.

Even if you use Calcemin alone, this will be enough to reduce pain syndrome in the spine and normalization of bone mineral density in patients with postmenopausal osteoporosis. The drug is well tolerated and practically does not cause any unwanted side effects. adverse reactions. The microelements included in its composition have the most positive effect on cartilage tissue, which makes possible use Calcemin for osteochondrosis, osteoarthrosis, traumatic injuries individual parts of the musculoskeletal system, as well as to normalize phosphorus-calcium metabolism in older people (mainly in women during menopause). The drug is also in demand during pregnancy, as aid in the treatment of periodontal diseases, in children's and adolescence during active growth. When using Calcemin, you should not go beyond the doses specified by the manufacturer, because V otherwise Excess calcium may inhibit absorption into digestive tract other essential macro- and microelements. The drug is taken one tablet twice a day (persons under 12 years old - once a day). Optimal time intake - before meals or during meals, although this, as noted above, is not of fundamental importance. It is best to take the tablet with water or juice. Duration of treatment - up to 1 month with the possibility of extending the course in consultation with the doctor.

Pharmacology

A combined preparation containing calcium, vitamin D 3, osteotropic minerals that regulate calcium metabolism. The pharmacological effect of the drug is determined by the properties of its constituent components.

Calcium is involved in the formation of bone tissue, reduces resorption and increases bone density, prevents diseases of the musculoskeletal system, and helps strengthen bone tissue and joints. Calcium citrate ensures calcium absorption regardless of functional state Gastrointestinal tract, which is applicable for the treatment of patients with reduced secretory function Gastrointestinal tract, as well as during treatment with drugs to reduce secretion; reduces the level of bone resorption markers, which indicates a slowdown in the processes of bone tissue destruction; regulates the content of parathyroid hormone, which leads to improved regulation of calcium homeostasis; does not increase the content of oxalates and calcium in the urine, therefore does not cause the formation of kidney stones; does not block the absorption of iron, which reduces the risk of developing iron deficiency anemia.

Colecalciferol (vitamin D 3) regulates the exchange of calcium and phosphorus in the body, participates in the formation of the bone skeleton, helps maintain bone structure, enhances the absorption of calcium in the intestines and the reabsorption of phosphorus in the renal tubules.

Zinc promotes the synthesis of sex hormones, which prevents the destruction of bone tissue.

Manganese is involved in the formation of proteoglycans, which improves the quality of bone tissue and forms the protein matrix of bone tissue.

Copper is involved in the synthesis of collagen and elastin, which are part of bone and connective tissue, which affects the processes of bone mass formation.

Boron reduces excessive activity of parathyroid hormone, improves calcium absorption, reduces the risk of developing colecalciferol deficiency, and helps prevent osteoporosis.

Pharmacokinetics

Release form

Film-coated tablets white, oval, biconvex, with a notch on one side.

Excipients: soy polysaccharide - 10 mg, sodium lauryl sulfate - 5 mg, colloidal silicon dioxide - 3.9 mg, croscarmellose sodium - 28 mg, microcrystalline cellulose - 199.45 mg, stearic acid - 35 mg, magnesium stearate - 10 mg.

Shell composition: hypromellose - 11.71 mg, triacetin - 2.53 mg, mineral oil - 1.27 mg, sodium lauryl sulfate - 4 mcg, titanium dioxide - 7.03 mg, magnesium silicate - 5 mg.

30 pcs. - polyethylene bottles high density(1) - cardboard packs.
60 pcs. - bottles made of high-density polyethylene (1) - cardboard packs.
120 pcs. - bottles made of high-density polyethylene (1) - cardboard packs.

Dosage

The drug is taken orally.

Adults and children over 12 years of age are prescribed 1 tablet. 2 times/day during meals.

Children aged 5 to 12 years are prescribed 1 tablet. 1 time/day during meals.

From the 20th week of pregnancy and throughout the entire period breastfeeding 1 tablet is prescribed. 2 times/day.

Minimum duration of use of the drug for the treatment of osteoporosis in the composition complex therapy in adults it is 3 months, for the prevention of osteoporosis in adults - 1 month, for calcium and microelements deficiency in children and adults - 2-3 months. Increasing the duration of use of the drug is possible only after consultation with a doctor.

A second course of taking the drug is possible 1 month after the end of treatment.

Overdose

In case of an overdose of the drug, hypervitaminosis D, hypercalcemia and hypercalciuria may develop.

Symptoms: loss of appetite, thirst, polyuria, dizziness, fainting states, constipation, nausea and vomiting. With long-term use in high doses - calcification of blood vessels and tissues.

Treatment: it is necessary to reduce the dose or stop using the drug. In case of accidental overdose, induce vomiting and rinse the stomach. Symptomatic therapy is indicated.

Interaction

At simultaneous use The drug Kalcemin ® with vitamin A reduces the toxicity of vitamin D 3 .

Phenytoin, barbiturates, and glucocorticoids reduce the effectiveness of vitamin D 3 .

Laxatives reduce the absorption of vitamin D 3 .

Glucocorticoids, hormonal contraceptives for systemic use, levothyroxine impairs the absorption of calcium ions.

When used simultaneously with tetracycline, the interval between doses should be at least 3 hours, with bisphosphonates and sodium fluoride - at least 2 hours (their absorption is impaired).

At joint use the drug Calcemin ® with cardiac glycosides increases the toxicity of the latter (monitoring of ECG and clinical condition is necessary).

When used simultaneously with thiazide diuretics, the risk of developing hypercalcemia increases; with furosemide and other “loop” diuretics, the excretion of calcium by the kidneys increases.

Calcemin ® should not be used simultaneously with calcium channel blockers.

Side effects

From the outside digestive system: nausea, vomiting, flatulence, diarrhea, constipation.

Metabolism: hypercalcemia and hypercalciuria.

Allergic reactions: itching, rash, urticaria.

Indications

The drug should be prescribed with caution in cases of benign granulomatosis, simultaneous use of cardiac glycosides and thiazide diuretics, pregnancy, and lactation.

Features of application

Use during pregnancy and breastfeeding

During pregnancy and lactation, the use of the drug should be agreed with a doctor.

The daily dose should not exceed 1500 mg of calcium and 600 IU of vitamin D 3 . Hypercalcemia, which develops against the background of an overdose during pregnancy, can cause mental and mental defects. physical development in the fetus.

In lactating women, it should be taken into account that colecalciferol and its metabolites are excreted with breast milk Therefore, it is necessary to take into account the intake of calcium and vitamin D 3 from other sources.

Use for renal impairment

The use of the drug is contraindicated when renal failure severe, urolithiasis.

Use in children

The use of the drug in children under 5 years of age is contraindicated.

special instructions

When using the drug, you should not exceed the recommended dose, because increased consumption calcium can inhibit the intestinal absorption of iron, zinc and other essential minerals.

Impact on the ability to drive vehicles and operate machinery

Calcemin Advance is a complex drug that helps correct the level of phosphorus-calcium metabolism in the blood plasma. The medicine is prescribed to adults and children for complex treatment and prevention of musculoskeletal diseases. Instructions for use of Calcemin Advance will allow you to familiarize yourself in detail with the pharmacological action of the drug.

Calcemin Advance is combination drug, which contains micro- and macroelements, vitamins; pharmachologic effect due to the properties of the components included in its composition:

• Calcium increases the density and resection of bone tissue, participates in its formation, reduces resorption, and helps strengthen joints and bone tissue. Calcium citrate normalizes calcium absorption regardless of the state of the gastrointestinal tract, which allows the drug to be taken by patients with reduced secretory function of the gastrointestinal tract; reduces the level of bone tissue markers, which indicates a slowdown in the processes of its destruction; regulates calcium levels and, accordingly, prevents the formation of kidney stones; promotes the absorption of iron, thereby significantly reducing the risk of developing IDA, regulates the content of parathyroid hormone in the blood, which improves the regulation of calcium homeostasis.
• Colecalciferol (vitamin D 3) regulates and replenishes the metabolism of calcium and phosphorus, effectively affects the strengthening of bone structure, affects the reabsorption of phosphorus in the renal canals and the absorption of calcium in the intestine.
• Zinc helps strengthen bone tissue and has a beneficial effect on the synthesis of sex hormones.
• Magnesium promotes the formation of muscle and bone tissue. Magnesium and zinc are necessary for the human body for the process of synthesizing organic bone matrix.
• Copper regulates the process of collagen synthesis, providing positive impact on the formation of bone mass.
• Manganese forms the matrix of bone tissue, participates in the formation of proteoglycans, thereby improving the strength of bone tissue.
• Boron improves calcium absorption, reduces the activity of parathyroid hormone, reduces the risk of developing colecalciferol deficiency, and prevents the development of osteoporosis.

Release form

Dosage form: tablets.

Tablet color: pink.

Shape: biconvex, oval, lined on one side.

Type of packaging: polyethylene bottle, each packed in a cardboard pack.

The drug is available in 3 dosages: 30, 60, 120 pcs. in each bottle.

Composition of the drug

Active substances in one tablet:

• calcium (calcium carbonate, calcium tetrahydrate);
• colecalciferol (vitamin D 3);
• magnesium (magnesium oxide);
• zinc (zinc oxide);
• copper (copper oxide);
• manganese (manganese sulfate);
• boron (sodium borate decahydrate).

Excipients:

• core: maltodextrin, sodium lauryl sulfate, soy polysaccharide, stearic acid, croscarmellose sodium, microcrystalline cellulose;
• shell: mineral oil, hypromellose, titanium dioxide, triacetin, magnesium silicate, aluminum varnish (Red No. 40) – 0.315 mg; aluminum varnish (Yellow No. 6) – 0.078 mg, aluminum varnish (Blue No. 1) – 0.05 mg.

Instructions for use

Calcemin Advance has several indications for use. Doctors prescribe it for the complex treatment of diseases of the musculoskeletal system and for preventive purposes.

The medicine does not relieve inflammatory process, pain, does not provide antimicrobial effect, does not help with fever, it has a different mechanism of action - it provides the body essential microelements and vitamins.

• therapy and prevention of osteoporosis;
• treatment of many diseases of the musculoskeletal system;
• improved consolidation of fractures and injuries;
• long-term use of immunosuppressants;
• treatment of bone resorption;
• menopause period;
• lack of calcium;
• preventive measures in dentistry;
• replenishment of trace elements and minerals during the period increased need(development of the musculoskeletal system, fractures, pregnancy, lactation).

Before you start taking the drug, you need to consult a specialist.

Calcemin Advance for children

Indications for use of the medicine for children:

• deficiency of vitamins and microelements;
• diseases of the musculoskeletal system;
• injuries, fractures, etc.

The dosage of the drug is determined by a specialist after a comprehensive examination.

Pregnancy and lactation

During pregnancy or lactation, Calcemin Advance can be taken only as prescribed by a doctor. It is prohibited to exceed the dosage of the drug prescribed for this period, since an excess of calcium in the body of a pregnant woman negatively affects the development of the fetus - leads to hypercalcemia, syndrome aortic stenosis, epilepsy. The fetus may also experience developmental delay and lack of growth.

When breastfeeding, it is worth considering that the components of the drug enter the baby’s body, so it is recommended to take the drug under the supervision of a specialist.

Drug interactions

Calcemin Advance can reduce the effectiveness of certain drugs: antibiotics, antiviral agents, fluorides, phosphates, diuretics, antacids, while reducing the amount of absorbed calcium. If you use several drugs at the same time, including Calcemin Advance, you need to notify your doctor.

Also, due to the use of orlistan, ion exchange salts and laxatives, the absorption of vitamin D3 can be significantly reduced. It is recommended to take a break of several hours between doses. Phenytoin, carbamazepine, barbiturates, and vitamin A can interfere with the absorption of vitamin D3.

Contraindications

This complex drug has some contraindications. Before purchasing it, be sure to read the instructions. The drug Calcemin Advance has absolute and relative contraindications.

TO absolute contraindications relate:

• vitamin D hypervitaminosis;
• hypercalciuria;
• hypercalcemia;
• severe history of renal failure;
• sarcoidosis;
• tuberculosis;
• intolerance to the components of the drug;
• age up to 12 years;
• urolithiasis disease;
• allergies to peanut butter, soy.

Relative contraindications (conditions/diseases in the presence of which the prescription of a medicine requires caution and specialist supervision):

• pregnancy and lactation;
• renal failure.

Dosage

The dosage of Calcemin Advance depends on the etiology of the disease. Complex remedy taken during meals. Before taking the drug, you should read the leaflet, which recommends the dosage regimen for Calcemin Advance:

• osteoporosis (prevention): 1 table. – once a day, use – 2 months;
• osteoporosis (as part of complex treatment): 2 times a day – 1 tablet, duration – 3 months;
• replenishment of calcium deficiency, improvement of consolidation of traumatic fractures: once a day, 1 tablet, use – 2 months.

Side effects

Most often, Calcemin Advance has no side effects, but with individual intolerance to the components, sensitivity, or prolonged use of the drug, some side effects may develop:

• headache;
• allergic reactions - redness, rashes, hives, dry skin;
• from the gastrointestinal tract - increased gas formation, abdominal pain, nausea, lack of appetite, feeling of heaviness in the stomach;
• changes in blood and urine test parameters - hypercalciuria and hypercalcemia.

Price

Calcemin Advance tablets are sold in dosages - 30, 60, 120 pcs. packaged. If the treatment lasts several months, the manufacturer offers significant savings when purchasing 60 or 120 tablets. packaged. This complex drug can be purchased in a pharmacy chain, in an online store and ordered from a catalog.

Cost of Calcemin Advance in chain pharmacies (average prices):

Analogs

Structural analogues in the main active substance the drug Calcemin Advance does not have. However, on pharmaceutical market There are many similar medicines based on vitamins and microelements.

• Vitrum Osteomag (tablets). Manufacturer: Unifarm Inc. (USA). The drug has differences in composition, but is used when the same problems occur as Kalcemin Advance: osteoporosis, calcium deficiency, vitamin D3, for therapeutic and prophylactic purposes. Contraindicated under the age of 12 years and hypersensitivity body to the components of the drug. Available in tablet form: price from 378 rubles.
• Calcium-D3 Nycomed (chewable tablets). Manufacturer: Nycomed Pharma AS (Norway). Contains a comprehensive list of contraindications, as well as age restrictions. The drug is based on calcium, produced in the form of chewable tablets: 30 pieces, price from 221 rubles.

Cheap analogues of Calcemin Advance:

Complivit calcium D3 (chewable tablets). Manufacturer: Pharmstandard-UfaVITA (Russia). The drug is in the same pharmacological group as Calcemin Advance, but it contains only two active ingredients. Indications for use contain the same points. Sold in form chewable tablets: 30 pieces, price from 138 rubles.

Overdose

An overdose of the drug can lead to hypervitaminosis, hypercalciuria, hypercalcemia.

Symptoms of drug overdose: loss of appetite, headache, dizziness, thirst, polyuria, nausea, vomiting, constipation, fatigue, muscle weakness, bone pain, fainting, coma, mental disorders, urolithiasis, rarely - cardiac arrhythmias.

Long-term use of calcium can provoke calcification of soft tissues and inflammation of the kidneys.

Treatment of overdose. If signs of overdose are detected, you must immediately reduce the dose or stop using the drug. If an overdose is caused by accidental circumstances, induce vomiting and rinse the stomach. IN special cases carry out symptomatic therapy.

Name:

Calcemin

Pharmachologic effect:

Mineral and vitamin complex. Calcium, which is part of the drug, is a building component for bone tissue, regulates the permeability of the vascular wall, is involved in the regulation of conductivity in synapses and neuromuscular junctions, is involved in the contractile activity of skeletal and smooth muscles, and is a necessary component for the blood clotting process. Calcium is presented in the preparation as carbonate and citrate salts. Calcium carbonate contains maximum amount elemental calcium. Calcium citrate reduces the dependence of the process of calcium bioavailability on the state of the gastrointestinal mucosa and prevents stone formation in urinary system even in case long-term use, reduces excess production of parathyroid hormone.

Vitamin D (cholecalciferol) promotes adequate calcium absorption and is involved in the processes of regeneration and bone tissue building.

Zinc is integral component various enzymes of the body (more than 200 types) that synthesize proteins and nucleic acids. It also provides gene expression, regeneration and cell growth. Positively affects the activity of the enzyme alkaline phosphatase.

Manganese promotes the synthesis of substances that are components of bone and cartilage tissue(glycosaminoglycans). Potentiates the calcium-sparing ability of vitamin D.

Copper is involved in the formation of elastin and collagen. Helps stop the phenomenon of demineralization of bone structures.

Boron normalizes hormone activity parathyroid gland– parathyroid hormone. The latter is involved in the metabolism of calcium, cholecalciferol, phosphorus, and magnesium. Influence at mineral metabolism parathyroid hormone does not depend on the supply of vitamin D3.

Calcium is absorbed from the gastrointestinal tract and eliminated from the body in urine, sweat and feces. Calcium absorption is possible due to the activity of calbindin, an enzyme in the intestinal mucosa. The biosynthesis of calbindin directly depends on calcitriol, a metabolite of vitamin D.

Vitamin D is absorbed quickly from the intestines. Penetrates into bones, liver, adrenal glands, adipose tissue, heart muscle. When vitamin D is excreted in the bile, it is reabsorbed. Partially transformed into inactive metabolites.

Zinc is eliminated by the kidneys (10%) and intestines (90%).

Copper is partially absorbed from the intestine, the rest is eliminated unchanged or in the form of insoluble complexes. 80% of the administered copper is excreted in the bile, 16% in the intestines, 4% in the kidneys, and a very small amount in the sweat glands.

After absorption from the intestine, boron is excreted by the kidneys (90%).

Indications for use:

· prevention of osteoporosis and other diseases musculoskeletal system,

· prevention of dental and periodontal diseases,

· replenishing the deficiency of vitamins and minerals in case of insufficient amounts in the diet,

· children – during the period of intensive growth,

· pregnant and lactating women.

Method of application:

For children over 12 years old and adults – 1 tablet, 2 r/s. Children from 5 to 12 years old – 1 tablet 1 r/s. Tablets are taken before meals or during meals. The duration of therapy is determined individually; there are no time restrictions. Pregnant and nursing mothers are prescribed 1 tablet 2 times a day. The drug is prescribed no earlier than 20 weeks of pregnancy.

Adverse events:

More often observed in case of drug overdose (hypersensitivity reactions to calcemin components, nausea, flatulence, vomiting, hypercalciuria, hypercalcemia).

Contraindications:

hypersensitivity reactions (allergic) to the components of the drug,

hypercalciuria,

hypercalcemia,

· kidney stone disease.

During pregnancy:

Not contraindicated during pregnancy and breastfeeding.

Interaction with other drugs:

Calcemin should not be used together with calcium antagonists.

Overdose:

There are no reports of cases of calcemin overdose. If the dose has been exceeded, it is prescribed symptomatic treatment(gastric lavage, administration drink plenty of fluids, eating foods low in calcium).

Release form of the drug:

Tablets containing 250 mg of elemental calcium, white, capsule-like, with a notch on one side. The tablets are packaged in a polyethylene bottle. The bottle contains 30, 60, 120 tablets.

Storage conditions:

Shelf life – 3 years at a temperature of 25-30°C. Keep away from light. Keep out of reach of children.

Compound:

Active ingredients: calcium citrate 842 mg, calcium carbonate 202 mg, cholecalciferol 50 IU, copper 0.5 mg, zinc 2 mg, boron 50 mcg, manganese - 5 mg.

Inactive Ingredients: microcrystalline cellulose, magnesium stearate, acacia, sodium lauryl sulfate, croscarmellose sodium, starch, cottonseed oil, calcium phosphate, gluten, sodium citrate, stearic acid, hydroxypropylcellulose, maltodextrin, sugar, hydroxypropylmethylcellulose, titanium dioxide, gelatin, tocopherol, polyethylene glycol.

Additionally:

Children under 5 years of age may only use the drug according to strict indications. Children of this age should take the drug only under the supervision of a doctor.

Drugs with similar effects:

Immunovit Quertin Ascozin Retinol acetate Wolvit

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Calcemin is a vitamin-mineral complex.

Pharmacological action of Calcemin

Calcemin is a vitamin-mineral complex that includes calcium, vitamin D, zinc, manganese, boron, and copper.

Calcium is an important element for bone tissue, it regulates permeability vascular wall, conductivity in neuromuscular junctions, synapses, takes part in the contraction of smooth, skeletal muscles, in the process of blood clotting. In the Kalcemin complex, calcium is represented by citrate and carbonate salts. Calcium carbonate contains a large number of elemental calcium. Calcium citrate reduces the dependence of the state of the gastrointestinal mucosa and the bioavailability of calcium.

Vitamin D is included in the Calcemin complex to ensure better absorption of calcium; it is also involved in the construction of bone tissue and its regeneration.

Zinc is part of various body enzymes that produce nucleic acids and proteins; it ensures gene expression, cell growth and regeneration, and stimulates the activity of the alkaline phosphatase enzyme.

Manganese helps the production of cartilage and bone tissue components and provides the calcium-sparing effect of vitamin D.

Copper takes part in the synthesis of collagen and elastin, and inhibits the demineralization of bone structures.

Boron restores the activity of parathyroid hormone, produced by the thyroid gland and involved in the metabolism of calcium, magnesium, vitamin D, and phosphorus.

Release form

Kalcemin is produced in the form of tablets containing elemental calcium 250 mg and 500 mg - Kalcemin Advance.

Indications for use

Calcemin according to the instructions is used for the prevention of osteoporosis and other diseases of the musculoskeletal system, for the prevention of periodontal disease, dental diseases, to replenish the deficiency of minerals and vitamins in a poor diet.

There are good reviews about Kalcemin, which is given to children during a period of intensive growth. Calcemin is prescribed during pregnancy and lactation to maintain sufficient levels of minerals and vitamins in the body.

Calcemin Advance is prescribed to women during menopause and to patients taking glucocorticosteroids and immunosuppressants.

There are also good reviews about Kalcemin with an enhanced composition, used to improve the consolidation of fractures, to compensate for the deficiency of calcium and microelements in adolescents, for the prevention and treatment of osteoporosis of various origins.

Instructions for use of Calcemin

According to the instructions, Calcemin is prescribed for children over 12 years of age, for adults, 1 tablet twice a day. Children 5-12 years old. – 1 tablet once a day. Take vitamins during or before meals. The duration of therapy is determined individually; there are no time limits.

Calcemin during pregnancy is prescribed one tablet two times a day. The drug is prescribed only after the 20th week of pregnancy. During pregnancy, Calcemin with more high content calcium and other components are used with caution.

Calcemin Advance is prescribed to adults and children over 12 years of age. 1 tablet twice a day, take vitamins with meals.

If Calcemin Advance is prescribed to compensate for the deficiency of mineral salts and calcium, it is taken 1 tablet per day.