Rinza side effects. Rinza - anti-cold remedy

Drug for symptomatic therapy acute respiratory diseases.

Drug: RINZA ®


Active substance: comb. drug
ATX code: N02BE51
KFG: Drug for symptomatic treatment of acute respiratory diseases
Reg. number: P No. 015798/01
Registration date: 06/28/04
Owner reg. cred.: UNIQUE PHARMACEUTICAL Laboratories (India)


DOSAGE FORM, COMPOSITION AND PACKAGING

?Pills round, flat, Pink colour with dark pink and white flecks, with beveled edges and a dividing line on one side.

Excipients: colloidal silicon dioxide, crimson dye 4R, corn starch, povidone (K-30), sodium methylhydroxybenzoate, magnesium stearate, purified talc, sodium starch glycolate, purified water.

10 pieces. - blisters (1) - cardboard packs.
10 pieces. - blisters (2) - cardboard packs.
10 pieces. - blisters (10) - cardboard packs.


The description of the drug is based on the officially approved instructions for use.

Pharmachologic effect:

The combined agent has antipyretic, analgesic, alpha-adrenergic stimulating, vasoconstrictor and antihistamine effects, eliminating the symptoms of a “cold”. Caffeine stimulates the psychomotor centers of the brain, enhances the effect of analgesics, eliminates drowsiness and fatigue, increases physical and mental health. mental performance, shortens reaction time, temporarily reduces fatigue and drowsiness. Paracetamol - non-narcotic analgesic; blocks COX, mainly in the central nervous system, affecting the centers of pain and thermoregulation; has analgesic and antipyretic effects. Phenylephrine is an alpha-adrenergic agonist with a moderate vasoconstrictor effect. Chlorphenamine is a H1-histamine receptor blocker. Constricts nasal vessels, eliminates swelling and hyperemia of the mucous membrane of the nasal cavity, nasopharynx and paranasal sinuses nose; reduces exudative manifestations, suppresses the symptoms of allergic rhinitis.


Indications:

Feverish syndrome ("colds" and infectious diseases); Sinusitis, rhinorrhea ( acute rhinitis, allergic rhinitis).


Contraindications:

Hypersensitivity, severe atherosclerosis coronary arteries, arterial hypertension (severe course), diabetes (severe), pregnancy, lactation, childhood(up to 6 years). With caution. Glucose-6-phosphate dehydrogenase deficiency; liver and/or renal failure, angle-closure glaucoma, prostatic hyperplasia; congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndromes), arterial hypertension, thyrotoxicosis, diabetes mellitus, COPD (pulmonary emphysema, Chronical bronchitis), simultaneous administration MAO inhibitors and beta-blockers.


Side effects:

Allergic reactions ( skin rash, itching, urticaria, angioedema), nausea, epigastric pain; anemia, thrombocytopenia, agranulocytosis. Increased excitability, dizziness, increased blood pressure, difficulty falling asleep. Mydriasis, accommodation paresis, increased intraocular pressure, dry mouth; urinary retention. At long-term use in large doses - hepatotoxic effect, hemolytic or aplastic anemia, methemoglobinemia, pancytopenia; nephrotoxicity (renal colic, glycosuria, interstitial nephritis, papillary necrosis).Overdose. Symptoms: paracetamol (when taken over 10-15 g) - pallor skin, loss of appetite, nausea, vomiting, toxic hepatitis, up to the development of hepatonecrosis, increased activity of “liver” transaminases, increased prothrombin time. Treatment: symptomatic, gastric lavage, administration of SH-group donors and precursors for the synthesis of glutathione - methionine 8-9 hours after an overdose and N-acetylcysteine ​​- after 12 hours.


Directions for use and dosage:

Orally, adults - 1-2 tablets with an interval of 4-6 hours. Maximum daily dose- 12 tablets. Children over 6 years old - 1 tablet every 4 hours; The maximum daily dose is 5 tablets for no more than 7 days.


Special instructions:

During the treatment period, indicators are monitored peripheral blood And functional state liver. During the treatment period, you should not take sleeping pills and anxiolytic drugs (tranquilizers). Do not take with other drugs containing paracetamol. If symptoms do not go away within 5 days, you should consult a doctor. During the treatment period, it is necessary to refrain from drinking ethanol (possible development of hepatotoxic effects), driving vehicles and other potentially potentially dangerous activities. dangerous species activities that require increased concentration and speed of psychomotor reactions.


Interaction:

Enhances the effects of MAO inhibitors, sedatives, ethanol. Ethanol enhances sedative effect antihistamines. Antidepressants, antiparkinsonian and antipsychotic drugs, phenothiazine derivatives increase the risk of developing urinary retention, dry mouth, and constipation. GCS increase the risk of developing glaucoma. Paracetamol reduces the effectiveness of uricosuric drugs. Chlorphenamine simultaneously with MAO inhibitors, furazolidone can lead to hypertensive crisis, agitation, hyperpyrexia. Tricyclic antidepressants enhance the adrenomimetic effect of phenylephrine; simultaneous administration of halothane increases the risk of developing ventricular arrhythmia. Reduces hypotensive effect guanethidine, which in turn enhances the alpha-adrenergic stimulating activity of phenylephrine.

On average, people get colds 2-3 times a year. It is especially easy to catch a cold in the autumn-winter period. How to deal with the disease? Among large quantity medicines occupies a worthy place Rinza. How and whether it can be taken during pregnancy and children, how to drink the powder, what are the indications, contraindications for taking the drug, are there any inexpensive analogues? Details are in our article.

Indications for use of Rinza

What does it help with? Rinza? It, according to the instructions for use, is prescribed for the first symptoms of ARVI, influenza and other colds and infectious diseases.

Here is a list of indications for which Rinza is prescribed:

  • antipyretic,
  • psychostimulating,
  • antihistamine,
  • analgesic.

Rinza, according to the instructions, helps with:

  • pain (headaches, dental, muscle and joint pain),
  • acute rhinitis, sinusitis, rhinopharyngitis,
  • burns and injuries,
  • neuralgia, myalgia, arthralgia.

For those for whom the use of tablets is various reasons impossible, analogues are prescribed in a different form (say, powder).

Contraindications for use

The instructions for use clearly indicate that Rinza and Rinzasip are contraindicated during pregnancy and for children.

Here is a list of other contraindications in the form:

  • sensitivity to the components of the drug,
  • hypertension,
  • atherosclerosis,
  • severe form of diabetes mellitus,
  • taking tricyclic antidepressants, MAO inhibitors, medications containing the same components as in Rinze(if these or other drugs are indicated, you should consult a doctor).
  • liver and kidney failure,
  • glaucoma,
  • prostatic hyperplasia,
  • diabetes,
  • thyrotoxicosis, etc.

During the course of treatment with Rinz, it is not advisable to drive vehicles or perform work with increased concentration attention, where a quick psychomotor reaction is required.

Side effects can be observed from:

  • central nervous system (dizziness, difficulty falling asleep or increased excitability),
  • cardiovascular system (increased blood pressure, tachycardia),
  • digestive system (vomiting, nausea, dry mouth, epigastric pain, impaired liver function),
  • vision (increased intraocular pressure, mydriasis, accommodation paresis),
  • hematopoietic system (anemia, agranulocytosis, aplastic anemia, thrombocytopenia, methemoglobinemia, hemolytic anemia, pancytopenia),
  • urinary system (urinary retention, papillary necrosis of the kidneys),
  • respiratory system (bronchial obstruction).

Overdose: in acute cases, nausea, vomiting, diarrhea, and increased sweating may occur; observed in chronic cases severe violations liver functions,

Composition of Rinza tablets and powder

1 tablet Rinses contains basic and additional substances.

Here is a list of the main ones:

  • 10 mg phenylephrine hydrochloride,
  • 30 mg caffeine,
  • 2 mg chlorphenamine maleate.

List of additional substances:

  • magnesium stearate,
  • sodium methyl parahydroxybenzoate,
  • corn starch,
  • sodium carboxymethyl starch,
  • colloidal silicon dioxide,
  • povidone (K-30),
  • talc,
  • crimson dye.

Release form: tablets and powder.

Instructions for use of Rinza tablets

Pills Rinza taken orally. The instructions say that a single dose for adults and children over 15 years of age is 1 tablet. (maximum – 2, but no more than 4 pieces per day). The frequency of administration is 3-4 times a day. Take within 5 days.
Drink 1.5 hours after meals with the required amount of water.

Rinzasip

  • Taken orally. Adults drink a sachet 3-4 times a day. Intervals between doses are 4-6 hours.
  • Take no more than 4 sachets per day for 5 days.
  • A packet of powder dissolves in a glass hot water; After stirring, drink (adding honey and sugar if desired).

Instructions for children

  • According to the instructions, children under 15 years old this drug not written out. A child who has reached this age is prescribed 1 sachet 3-4 times a day (no more than 4 pieces). The interval between doses is 4-6 hours.
  • The course of treatment is no more than 5 days.
  • The powder is poured warm water, dissolve and give to the child.

Rinza Lorsept

Rinza Lorcept: antiseptic, lozenges (with lemon, orange, blackcurrant flavor).

  • Shown: locally in ENT practice for infectious and inflammatory diseases of the oral cavity and pharynx (pharyngitis, tonsillitis, laryngitis, hoarseness, etc.) and in dentistry (for thrush, gingivitis, stomatitis).
  • Action: anesthetic, anti-inflammatory, analgesic, antifungal, bactericidal;
  • Side effects: expressed by allergic reactions.
  • In case of overdose: There may be vomiting, diarrhea, nausea.
  • Application: for adults, dissolve one tablet every 2-3 hours (no more than 8 tablets per day).
  • A course of treatment- 5 days.

The effect is noticeable in initial stages diseases. If symptoms do not go away after 3 days, you should contact the clinic.

There are no indications for use by children or during pregnancy. Cannot be consumed Rinzu If you are particularly sensitive to the components of the drug, exceed the dose indicated in the instructions. Drink with caution in case of epilepsy, cardiac conduction disorders, shock, liver dysfunction, patients with diabetes mellitus, with a hypocaloric diet.

Rinza Hotsip with vitamin C

  • Shown: for the symptomatic treatment of colds, flu, ARVI, colds, accompanied by fever, impaired nasal breathing, headache, runny nose, sneezing and lacrimation, with inflammation of the paranasal sinuses.
  • Action: analgesic, antipyretic, analgesic, vasoconstrictor, anti-inflammatory.
  • Not shown: at hypersensitivity to the components of the drug, high blood pressure, tachycardia, thyrotoxicosis, severe liver or kidney dysfunction, hyperthyroidism, diabetes, heart disease.
  • In case of overdose: vomiting, nausea, anorexia, abdominal pain, sweating, hepatonecrosis may develop.
  • Side effects: Rinza well tolerated, but in some cases side effects expressed by dry mouth, impaired visual accommodation, urinary retention, increased excitability (more often in older people); rarely side effects include nausea, vomiting, abdominal pain, tremor, insomnia, headache, convulsions, allergic reactions, leukopenia, renal colic, heart rhythm disturbances.
  • Application: By diluting the powder Rinses in a glass of hot water, drink the solution 3 times a day with an interval of at least 4 hours. The course is 5 days. In case of renal dysfunction, the interval between doses is increased to 8 hours.

It is necessary to be treated as soon as the first signs of the disease appear. It is better to avoid alcohol, which enhances the sedative effect Rinza, which is dangerous when driving and operating machinery.

To treat colds, ARVI and flu in children, parents strive to use effective and safe drugs. Medicines that contain several components that gently relieve different symptoms diseases are very popular. Read our article on how to treat children with Rinza.


Release form

Several multi-component remedies against influenza and colds are produced under the Rinza brand. These are “Rinza” tablets, packets of powder for preparing the “Rinzasip” drink and “Rinzasip for children”.

"Rinzasip-kids" has raspberry flavor, powder for adults – tastes of blackcurrant, lemon and orange.


Compound

Each Rinza tablet contains 30 mg of caffeine, 500 mg of paracetamol, 10 mg of phenylephrine hydrochloride and 2 mg of chlorphenamine maleate.

Caffeine is a natural psychostimulant that is found in many common drinks - coffee, tea, cola. In the body, caffeine stimulates the central nervous system, due to which it is included in medications for headaches and migraines.

Paracetamol is a well-known substance used in means to reduce body temperature and cold combination drugs. Phenylephrine hydrochloride has a vasoconstrictor effect, and chlorphenamine maleate has an antihistamine effect. Together, they quickly relieve the symptoms of flu and colds, alleviating the condition of the sick person.



Corn starch, magnesium stearate, talc and Ponceau 4R crimson dye are used as auxiliary components in the tablets.

One sachet of powder for children contains 100 mg of ascorbic acid, 280 mg of paracetamol, and 10 mg of pheniramine maleate. As is known, ascorbic acid is a source of vitamin C, and pheniramine maleate is an antiallergic agent.

Additionally in baby powder add:

  • natural coloring and flavoring;
  • sucrose and aspartame sweetener for taste, since ascorbic acid is very acidic;
  • Magnesium citrate, which promotes cellular energy.


The hot drink powder for children over 15 years of age has a different composition: it contains caffeine and is fortified with vitamin C and appropriate flavorings and sweeteners. In addition, an adult drink made from one packet contains much more paracetamol - 750 mg.


Operating principle

Rinza tablets have an antipyretic and analgesic effect due to the paracetamol content. The antiallergic effect of chlorphenamine also helps relieve edema, including those caused by seasonal allergies, for example, on the pollen of some plants. Caffeine stimulates the central nervous system, causing a surge of energy and improving overall health.


Children's "Renzasip" contains ascorbic acid, which is a source of vitamin C and quickly helps improve the child's condition.

Indications

Rinza preparations, regardless of the form - tablets or powder - are used to treat colds, acute respiratory infections, ARVI, influenza, including if these diseases occur with increased body temperature, fever, chills, headache and joint pain, strong current or nasal congestion. “Rinza” and “Rinzasip-kids” help with colds or allergic rhinitis.


At what age is it prescribed?

“Rinza” tablets and powder for preparing the “Rinzasip” drink are used in the treatment of children over 15 years of age. For children over 6 years old, use Rinzasip-Kids powder with raspberry flavor.

Doctors do not recommend giving children half or a quarter of a Rinza tablet, or part of the powder from an adult package, because they contain caffeine, which is not recommended for children due to its effect on the central nervous system. Secondly, it is difficult to determine the dosage of the drug, which can lead to symptoms of side effects or overdose.

If the child is already 5 years old, if other treatment is not possible, you can give him the Rinzasip-Kids drink. For a 3-year-old child, the dosage of paracetamol contained in the drink will be very high.

If the child is small and there are no medications with special pediatric dosages on hand, there is no need to give him adult medications. This can worsen the baby's condition.


Contraindications

There are absolute and relative contraindications to the drugs “Rinza”, “Rinzasip” and “Rinzasip-kids”.

Thus, children's powder is not used to treat children under 6 years of age, or if the child has an individual sensitivity to one or more components of the drug. It is prohibited to take “Rinza” by children who have severe liver and kidney dysfunction. In addition, Rinzasip Kids is not given to children with certain blood diseases.



Under no circumstances should Rinza-Kids be given to children who are already taking medications containing paracetamol, since one package contains a dose of this substance, the excess of which may result in an overdose.

TO relative contraindications relate:

  • diabetes mellitus - due to the content of sucrose, fructose, and sweeteners in the preparation;
  • stomach or duodenal ulcer;
  • some liver diseases;
  • taking medications that may adversely affect the function of the drug.


The drugs "Rinza" and "Rinzasip", approved for use from 15 years of age, are not given to children with diabetes mellitus, high blood pressure. The drug is prescribed with caution to children suffering from bronchial asthma, certain blood diseases, and renal failure.

Side effects

Among the possible side effects of the drug, the manufacturer lists allergic reactions– such as rashes and hives. The child may complain about headache, nausea, dry mouth.

These symptoms do not appear in all children, but only in in rare cases. As a rule, the reason is individual sensitivity to the components or excess dosage.

But whatever the reason, if parents notice one or more listed symptoms, even if they do not associate their appearance with taking the medicine, it is better to seek medical help.



At long-term treatment drug clinical tests can reveal anemia - insufficient level of hemoglobin in the blood, leukopenia - a decrease in the level of leukocytes in the blood, and other disorders.

Instructions for use

Rinza Kids is very easy to use for children. The powder from one package must be dissolved in 200 ml, which is equal to one standard glass of water.

Instructions for using powder for preparing a drink for children contain the following recommendations.

Children from six to ten years old can be given a drink from one package no more than twice a day, children from 10 to 12 years old - one package three times a day. From 12 years old, you can take one packet up to four times a day.

In this case, the interval between doses is at least 4 hours, A general course treatment is no more than five days in a row.

Rinza – combination drug for the treatment of acute respiratory diseases and relief of their main symptoms. Eliminates aches, pain in muscles, throat, joints, headaches, and has an antipyretic effect. In addition, Rinza helps relieve swelling of the mucous membranes and nasal congestion. Eliminates the feeling of drowsiness, increases performance. All this is achieved thanks to the content of Rinza (and this is the form in which the drug is produced): paracetamol (500 mg), caffeine (30 mg), phenylephrine hydrochloride (10 mg), chlorphenamine maleate (2 mg). As aids Rinza uses colloidal silicon dioxide, povidone, sodium methyl parahydroxybenzoate, talc, magnesium stearate, corn starch, crimson dye (Ponceau 4R), sodium carboxymethyl starch (type A).

Dispensed without a doctor's prescription.

Rinza tablets are round in shape, with beveled edges, flat, pinkish in color, with dark pink and. On one side with a dividing line. Available in 10 tablets per blister in a cardboard package or 2 blisters of 10 tablets in a cardboard package.

Indications for use and treatment

Rinza is recommended for the treatment of colds, flu, acute respiratory viral infections and the relief of accompanying symptoms: headaches, elevated temperature, sore throat, nasal congestion. The drug is also prescribed for people over 15 years of age. In older people, taking the drug is not recommended. You need to take Rinza 1 tablet 3-4 times a day, but no more than 4 tablets a day. The course of treatment can last up to five days. Do not exceed the dose indicated in the instructions.

Contraindications and side effects

You cannot combine Rinza with other products that contain the same components as Rinza.

Rinza should be used with caution when bronchial asthma, Gilbert's syndrome, Dubin-Johnson syndrome, Rotor syndrome, as well as with hepatic or renal failure, prostate, angle-closure glaucoma.

Side effects

While taking Rinza, side effects such as difficulty falling asleep, increased blood pressure, increased excitability, dizziness, nausea, vomiting, dry mouth, renal colic, nephritis, increased intraocular pressure, allergic reactions, itchy skin, rash, urticaria.

Storage conditions

The drug should be stored in a cool, dry place, out of reach. Shelf life – 3 years.

Description of the drug

Compound

Active:

  • 750 mg paracetamol;
  • 200 mg vitamin C;
  • 30 mg caffeine;
  • 20 mg pheniramine maleate.

Auxiliary:

  • orange:
  • citric:
  • blackcurrant:

Price

    • Hot drink 1 RINZASIP® with vitamin C helps eliminate the main symptoms of colds and flu. Thanks to the composition of the drug ascorbic acid, the product helps restore protective forces body to fight disease.

      Description of the drug

      The drug RINZASIP® with vitamin C has 3 different tastes: orange, lemon, blackcurrant.

      RINZASIP® Orange Powder with Vitamin C has a light orange to orange hue. There are white and orange inclusions. Blackcurrant powder for preparing a hot drink has a color from pinkish-red to pink. Red and white flecks may be present. Lemon powder – light yellow to yellow color with white and yellow splashes.

      Compound

      The composition of RINZASIP® with vitamin C (1 sachet, 5 g) includes the following substances.

      Active:

      • 750 mg paracetamol;
      • 200 mg vitamin C;
      • 30 mg caffeine;
      • 10 mg phenylephrine hydrochloride;
      • 20 mg pheniramine maleate.

      Auxiliary:

      • orange: 200.0 mg citric acid, 40.0 mg sodium saccharinate, 500.0 mg sodium citrate, 3062.5 mg sucrose, 7.5 mg sunset yellow coloring (E110), 150.0 mg orange flavor;
      • citric: 200.0 mg citric acid, 40.0 mg sodium saccharinate, 500.0 mg sodium citrate, 3136.0 mg sucrose, 1.0 mg yellow quinoline dye (E104), 83.0 mg lemon flavor;
      • blackcurrant: 200.0 mg citric acid, 40.0 mg sodium saccharinate, 500.0 mg sodium citrate, 2915.0 mg sucrose, 4.0 mg azorubine dye (E122), 166.7 mg Tutti Frutti fruit flavoring, 66.7 mg raspberry flavour, 66.7 mg blackcurrant flavour.

      Price

      The price of RINZASIP® with vitamin C in different pharmacies in Russia may vary slightly. The cost mainly depends on the region in which the product will be sold. You can get acquainted with the average market prices. Find out the specific cost of RINZASIP® with vitamin C, get up-to-date information You can find out about the availability of the product and where to buy it cheaper in pharmacy chains throughout Russia.

    • According to the instructions for medical use RINZASIP® with vitamin C, the drug must be taken orally. The contents of 1 sachet should be poured into a glass, pour hot boiled water and stir until completely dissolved. If desired, you can add honey or sugar. Children over 15 years of age and adults can take 1 sachet up to 4 times a day. The interval between doses should be 4–6 hours. Maximum dose– 4 sachets per day. If symptoms persist, you should see your doctor again.

    • RINZASIP® powder with vitamin C is prescribed as part of symptomatic treatment colds, flu, ARVI (febrile and pain syndromes, rhinorrhea). The combined agent has analgesic, antipyretic and antihistamine action. Thanks to this, it eliminates the main symptoms of colds and flu. The product contains a non-narcotic analgesic paracetamol, which has antipyretic and analgesic effects.

      Pheniramine helps eliminate itching in the throat, eyes and nose, relieve hyperemia and swelling of the mucous membranes of the nasal cavity, paranasal sinuses and nasopharynx. Caffeine enhances the analgesic effect of paracetamol 2. Phenylephrine produces moderate vasoconstrictor effect, and also helps reduce swelling and redness of the mucous membranes of the paranasal sinuses and upper respiratory tract. Ascorbic acid strengthens the immune system and increases the body's resistance to exposure negative factors external environment.

      • Hypersensitivity to the components of the drug RINZASIP® with vitamin C for colds;
      • severe atherosclerosis of the coronary arteries, portal hypertension;
      • pregnancy;
      • simultaneous use of analogues of RINZASIP® powder with vitamin C (i.e. products with the same active ingredients);
      • lactation period;
      • simultaneous use of monoamine oxidase inhibitors, tricyclic antidepressants, beta-blockers and discontinuation of their use less than 2 weeks ago;
      • children's age (up to 15 years);
      • fructose intolerance;
      • isomaltose/sucrose deficiency;
      • glucose-galactose malabsorption;
      • alcoholism.