ACC - instructions for use. How to drink ACC effervescent tablets, powder or cough syrup for adults and children. How to use ACC for cough correctly

ACC refers to mucolytic drugs that are prescribed for diseases respiratory tract. This drug increases the viscosity of bronchial secretions, has an expectorant effect and is, moreover, an antidote for poisoning with aldehydes, phenols and paracetamol. With the onset of the autumn season, the risk of colds increases, and the amount of vitamins in the body decreases. Why is the risk of catching a cold so great with the onset of cold weather and is it worth taking ACC?

Respiratory diseases

Respiratory tract infections are the most common and acute diseases that are observed on an outpatient basis. They are treated as common cold, and acute respiratory viral diseases. Rhinitis, laryngotracheitis, epiglottitis, bronchitis are prominent representatives of this group. Such infections are divided into diseases of the upper and lower respiratory tract. The upper ones include diseases of the nasal cavity - nasal passages, sinuses, larynx, pharynx. Diseases of the lower respiratory tract affect the bronchi and usually appear after inflammation of the nasopharynx.

Causes of respiratory tract infections

Diseases arise due to viruses entering the human body. They are often transmitted with a cough, i.e. If there is a sick person in your environment, the risk of infection is very high. And if you have a decrease in immunity, then this is generally favorable conditions for disease progression. In autumn and winter, our body is weakened, and there is a decrease in immunity.

In general, the risk can be observed not only in autumn and is influenced by following reasons: stress, excess sweet and fatty foods, wrong image life, smoking and alcohol, lack of sleep. In the fall, the holiday season ends for many people, workdays begin, and as a result, stress and lack of sleep, which is why the peak of decreased immunity and increased morbidity occur in the fall. And the airborne transmission mechanism infectious diseases promotes mass distribution in the shortest possible time.

Symptoms of diseases

Respiratory diseases are accompanied by various symptoms, which depend on the specific infection. The disease is accompanied by difficulty breathing, swelling of the inflamed area, and is often accompanied by mucous discharge. Diseases of the lower respiratory tract are accompanied by painful sensations in the throat and cough. At first the cough is usually dry, and then wet, sometimes it can provoke vomiting.

And although all diseases are successfully treated on an outpatient basis, the situation should not be left to chance, since many of them are advanced stage can lead to serious complications.

Traditional and non-traditional methods of treatment

Respiratory tract diseases, like any other diseases, are treated by two methods: the first (traditional) is prescribed to you by a doctor, the second (folk) we usually inherit. It is worth noting that, given the factor in the development of complications, you should not focus on self-medication and, as an option, it is worth combining traditional methods with traditional ones. Of course, after consulting your doctor first.

For lower respiratory tract infections, a number of drugs are usually prescribed to thin the mucus and have expectorant properties.

Types of medications prescribed for respiratory diseases:

1. – aimed at liquefying sputum and improving its fluidity without increasing volume. They reduce increased secretion of sputum due to their effect on goblet cells of the bronchial mucosa. These include direct-acting mucolytics that destroy complex chemical compounds as part of sputum. This includes drugs of the thiol group (which includes ACC), enzymes, and drugs with a different origin.
2. Mucolytics are not direct action change the composition of mucus and reduce its production, some reduce the adhesiveness of the gel layer.
3. Mucokinetics accelerate the release of mucus from the bronchial tree. This group includes many cough syrups (Lazolvan, Flavamed, Ambroxol, etc.)

Features of receiving ACC

ACC, as already mentioned, is a direct-acting mucolytic and its action is aimed at thinning sputum and reducing its secretion. This drug is prescribed for all diseases associated with the accumulation of sputum in the bronchial tree, namely: bronchitis, including obstructive, tracheitis, bronchial asthma, cystic fibrosis, laryngitis, sinusitis, exudative otitis media.

The active substance, acetylcysten, is almost immediately absorbed from the gastrointestinal tract, and maximum action achieved in 1-3 hours. The drug is approved for children from the 10th day of life. It is acceptable to take during pregnancy and lactation, but only under the supervision of a doctor.

It is worth noting that self-administration of any cough medications may interfere with correct positioning diagnosis, so they should be taken only after consulting a doctor.

Finally, a video is offered for viewing, which presents doctor’s advice regarding the prevention of respiratory organs:

Description of the dosage form

Effervescent tablets, 100 mg: round flat-cylindrical white, with the smell of blackberries. There may be a faint sulfuric odor. Reconstituted solution: colorless transparent with blackberry scent. There may be a faint sulfuric odor.

Granules for preparing a solution for oral administration (orange): homogeneous, white, without agglomerates, with the smell of orange.

Syrup: transparent, colorless, slightly viscous solution with a cherry odor.

pharmachologic effect

Pharmacodynamics

Acetylcysteine ​​is a derivative of the amino acid cysteine. Has a mucolytic effect, facilitates the discharge of sputum due to its direct effect on rheological properties sputum. The action is due to the ability to break the disulfide bonds of mucopolysaccharide chains and cause depolymerization of sputum mucoproteins, which leads to a decrease in its viscosity. The drug remains active in the presence of purulent sputum.

It has an antioxidant effect based on the ability of its reactive sulfhydryl groups (SH groups) to bind to oxidative radicals and thus neutralize them.

In addition, acetylcysteine ​​promotes the synthesis of glutathione, an important component of the antioxidant system and chemical detoxification of the body. The antioxidant effect of acetylcysteine ​​increases the protection of cells from the damaging effects of free radical oxidation, which is characteristic of an intense inflammatory reaction.

At prophylactic use acetylcysteine ​​there is a decrease in the frequency and severity of exacerbations bacterial etiology in patients with chronic bronchitis and cystic fibrosis.

Pharmacokinetics

Absorption is high. Rapidly metabolized in the liver to form a pharmacologically active metabolite - cysteine, as well as diacetylcysteine, cystine and mixed disulfides. Bioavailability when taken orally is 10% (due to the presence pronounced effect first pass through the liver). Tmax in blood plasma is 1-3 hours. Communication with blood plasma proteins is 50%. Excreted by the kidneys in the form of inactive metabolites (inorganic sulfates, diacetylcysteine). T1/2 is about 1 hour, impaired liver function leads to an extension of T1/2 to 8 hours. Penetrates the placental barrier. Data on the ability of acetylcysteine ​​to penetrate the BBB and be released from breast milk are missing.

Indications of the drug ACC ®

For all dosage forms

respiratory diseases accompanied by the formation of viscous, difficult to separate sputum:

Acute and chronic bronchitis;

Obstructive bronchitis;

Tracheitis;

Laryngotracheitis;

Pneumonia;

Lung abscess;

Bronchiectasis;

Bronchial asthma;

Chronic obstructive pulmonary disease;

Bronchiolitis;

Cystic fibrosis;

acute and chronic sinusitis;

inflammation of the middle ear (otitis media).

Contraindications

For all dosage forms

hypersensitivity to acetylcysteine ​​or other components of the drug;

peptic ulcer stomach and duodenum in the acute stage;

hemoptysis, pulmonary hemorrhage;

pregnancy;

period breastfeeding;

children under 2 years of age.

For effervescent tablets, 100 mg, additionally

lactase deficiency, lactose intolerance, glucose-galactose malabsorption.

Carefully: history of gastric and duodenal ulcers; bronchial asthma; obstructive bronchitis; hepatic and/or renal failure; histamine intolerance (should be avoided long-term use drug, because Acetylcysteine ​​affects histamine metabolism and may lead to signs of intolerance such as headache, vasomotor rhinitis, itching); varicose veins veins of the esophagus; adrenal gland diseases; arterial hypertension.

For granules for preparing a solution additionally

sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose deficiency.

Carefully: history of gastric and duodenal ulcers; arterial hypertension; varicose veins of the esophagus; bronchial asthma; obstructive bronchitis; adrenal gland diseases; liver and/or kidney failure; histamine intolerance (long-term use of the drug should be avoided, since acetylcysteine ​​affects the metabolism of histamine and can lead to signs of intolerance, such as headache, vasomotor rhinitis, itching).

Extra for syrup

Carefully: history of gastric and duodenal ulcers; bronchial asthma; liver and/or kidney failure; histamine intolerance (long-term use of the drug should be avoided, since acetylcysteine ​​affects the metabolism of histamine and can lead to signs of intolerance, such as headache, vasomotor rhinitis, itching); varicose veins of the esophagus; adrenal gland diseases; arterial hypertension.

Use during pregnancy and breastfeeding

Data on the use of acetylcysteine ​​during pregnancy and breastfeeding are limited. The use of the drug during pregnancy is possible only if the expected benefit to the mother outweighs the potential risk to the fetus.

If it is necessary to use the drug during lactation, the issue of stopping breastfeeding should be decided.

Side effects

According to WHO unwanted reactions classified according to their frequency of occurrence as follows: very common (≥1/10); often (≥1/100,<1/10); нечасто (≥1/1000, <1/100); редко (≥1/10000, <1/1000); очень редко (<1/10000); частота неизвестна — по имеющимся данным установить частоту возникновения не представлялось возможным.

Allergic reactions: uncommon - skin itching, rash, exanthema, urticaria, angioedema, decreased blood pressure, tachycardia; very rarely - anaphylactic reactions up to shock, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome).

From the respiratory system: rarely - shortness of breath, bronchospasm (mainly in patients with bronchial hyperreactivity in bronchial asthma).

From the gastrointestinal tract: uncommon - stomatitis, abdominal pain, nausea, vomiting, diarrhea; heartburn, dyspepsia (except syrup).

From the senses: infrequently - tinnitus.

Others: very rarely - headache, fever, isolated reports of bleeding due to a hypersensitivity reaction, decreased platelet aggregation.

Interaction

For all dosage forms

With the simultaneous use of acetylcysteine ​​and antitussives, sputum stagnation may occur due to suppression of the cough reflex. Therefore, such combinations should be selected with caution.

Simultaneous administration of acetylcysteine ​​with vasodilating agents and nitroglycerin can lead to increased vasodilatory effects.

When used simultaneously with antibiotics for oral administration (including penicillins, tetracyclines, cephalosporins), they may interact with the thiol group of acetylcysteine, which can lead to a decrease in their antibacterial activity. Therefore, the interval between taking antibiotics and acetylcysteine ​​should be at least 2 hours (except for cefixime and loracarbene).

Upon contact with metals and rubber, sulfides with a characteristic odor are formed.

Directions for use and doses

Inside, after meal.

Mucolytic therapy

Adults and children over 14 years of age: 2 tables each effervescent 100 mg 2-3 times a day or 2 packs. ACC ® granules for the preparation of a solution of 100 mg 2-3 times a day, or 10 ml of syrup 2-3 times a day (400-600 mg acetylcysteine ​​per day).

Children from 6 to 14 years old: 1 table each effervescent 100 mg 3 times a day or 2 tablets. effervescent 2 times a day, or 1 pack. ACC ® granules for preparing a solution 3 times a day or 2 packs. 2 times a day, or 5 ml of syrup 3-4 times a day or 10 ml of syrup 2 times a day (300-400 mg of acetylcysteine ​​per day).

Children from 2 to 6 years old: 1 table each. effervescent 100 mg or 1 pack. ACC ® granules for the preparation of a solution of 100 mg 2-3 times a day, or 5 ml of syrup 2-3 times a day (200-300 mg acetylcysteine ​​per day).

Cystic fibrosis

For patients with cystic fibrosis (an inborn error of metabolism with frequent bronchial tract infections) and a body weight of more than 30 kg, if necessary, the dose can be increased to 800 mg of acetylcysteine ​​per day.

Children over 6 years old: 2 tables each effervescent 100 mg or 2 packs. ACC ® granules 100 mg for solution 3 times a day, or 10 ml syrup 3 times a day (600 mg acetylcysteine ​​per day).

Children from 2 to 6 years old: 1 table each. effervescent 100 mg or 1 pack. ACC ® granules 100 mg for solution, or 5 ml syrup 4 times a day (400 mg acetylcysteine ​​per day).

Effervescent tablets should be dissolved in 1 glass of water and taken immediately after dissolution; in exceptional cases, the ready-to-use solution can be left for 2 hours.

Granules for oral solution (orange) should be dissolved in water, juice or iced tea and taken after meals.

Additional fluid intake enhances the mucolytic effect of the drug. For short-term colds, the duration of use is 5-7 days.

For chronic bronchitis and cystic fibrosis, the drug should be taken for a longer period of time to achieve a preventive effect against infections.

ACC ® syrup is taken using a measuring syringe or measuring cup contained in the package. 10 ml of syrup corresponds to 1/2 measuring cup or 2 filled syringes.

Using a measuring syringe

1. Open the bottle cap by pressing on it and turning it counterclockwise.

2. Remove the cap with the hole from the syringe, insert it into the neck of the bottle and press in until it stops. The stopper is designed to connect the syringe to the bottle and remains in the neck of the bottle.

3. Insert the syringe tightly into the stopper. Carefully turn the bottle upside down, pull the syringe plunger down and draw the required amount of syrup. If air bubbles are visible in the syrup, press the plunger all the way, then refill the syringe. Return the bottle to its original position and remove the syringe.

4. The syrup from the syringe should be poured onto a spoon or directly into the child’s mouth (into the cheek area, slowly, so that the child can swallow the syrup properly); the child should be in an upright position while taking the syrup.

5. After use, rinse the syringe with clean water.

Instructions for patients with diabetes: 1 effervescent tablet corresponds to 0.006 XE; 1 pack ACC ® granules for the preparation of a solution of 100 mg corresponds to 0.24 XE; 10 ml (2 scoops) of ready-to-use syrup contains 3.7 g of D-glucitol (sorbitol), which corresponds to 0.31 XE

Overdose

Symptoms: acetylcysteine, when taken at a dose of up to 500 mg/kg, did not cause any symptoms of intoxication. In case of an erroneous or intentional overdose, phenomena such as diarrhea, vomiting, stomach pain, heartburn and nausea may occur. Children may experience hypersecretion of sputum.

Treatment: symptomatic.

special instructions

When working with the drug, you must use glass containers and avoid contact with metals, rubber, oxygen, and easily oxidized substances.

Severe allergic reactions such as Stevens-Johnson syndrome and Lyell's syndrome have been very rarely reported with the use of acetylcysteine. If changes occur in the skin and mucous membranes, you should immediately consult a doctor and stop taking the drug.

In patients with bronchial asthma and obstructive bronchitis, acetylcysteine ​​should be prescribed with caution under systemic monitoring of bronchial patency.

You should not take the drug immediately before bedtime (it is recommended to take the drug before 18:00).

Impact on the ability to drive vehicles and operate machinery. There is no data on the negative effect of the drug in recommended doses on the ability to drive vehicles or use machinery.

Special precautions when disposing of unused medicinal products. There is no need for special precautions when disposing of unused drug.

Extra for syrup

The use of the drug should be avoided in patients with renal and/or liver failure to avoid additional formation of nitrogenous compounds.

1 ml of syrup contains 41.02 mg of sodium. This must be taken into account when using the drug in patients on a diet aimed at limiting sodium intake (reduced sodium/salt).

Release form

Effervescent tablets, 100 mg.

When packaging Hermes Pharma Ges.m.b.H., Austria: 20 tablets. effervescent in a plastic or aluminum tube. 1 tube of 20 tablets. effervescent in a cardboard box.

Granules for solution for oral administration (orange), 100 mg. 3 g granules in bags made of a combined material (aluminum foil/paper/PE). 20 packs in a cardboard box.

Syrup, 20 mg/ml. In dark glass bottles, sealed with white caps with a sealing membrane, child-resistant, with a protective ring, 100 ml.

Dosing devices:

Transparent measuring cup (cap), graduated at 2.5; 5 and 10 ml;

Transparent dosing syringe, graduated at 2.5 and 5 ml with a white piston and an adapter ring for attaching to the bottle.

1 fl. together with dosing devices in a cardboard box.

Manufacturer

Effervescent tablets

1. Hermes Pharma Ges.m.b.H., Austria.

2. Hermes Arzneimittel GmbH, Germany.

Granules for preparing a solution

Registration certificate holder: Sandoz d.d., Verovškova 57, 1000 Ljubljana, Slovenia.

Manufactured by: Lindopharm GmbH, Neustrasse 82, 40721 Hilden, Germany.

Syrup

Pharma Wernigerode GmbH, Germany.

Marketing authorization holder: Sandoz d.d. Verovškova 57, Ljubljana, Slovenia.

Many pathologies of the respiratory organs are accompanied by a painful cough. Moreover, regardless of whether it is dry or wet, the patient tries to get rid of this unpleasant symptom as soon as possible. In pharmacies you can find many medicines that will help cure a cough in a short time, including ACC. The medication can be prescribed for both dry and productive cough. ACC with a dry cough increases the volume of mucus produced and promotes its removal, and with a wet cough it helps to easily remove mucus from the respiratory organs.

General characteristics of the drug

The pharmaceutical industry produces the drug ACC in several doses and forms. There is also a long-acting drug that cannot be taken more than 2 times a day.. In pharmacies you can find the following forms of the drug:

• soluble cough tablets;
• solution for inhalation;
• powder, which when diluted in water produces a drink;
• sweet syrup. This form of medication is convenient to prescribe for the treatment of cough in a small child;
• solution for intravenous and intramuscular injections.

The active component of these dosage forms is acetylcysteine. In addition, each type of drug differs in some auxiliary components. Thus, the granules, among other things, contain citrus flavoring, the soluble tablets contain blackberry flavoring, and the syrup contains cherry flavoring.

ACC can be prescribed for both non-productive and wet coughs. The acetylcysteine ​​contained in the drug promotes the rapid removal of sputum from the bronchi and lungs. When taking ACC, the patient must drink a lot, in this case the effect of the drug is enhanced, and the sputum is cleared well.

The effect of this drug has not yet been fully studied.. Acetylcysteine ​​has a pronounced mucolytic, expectorant and antioxidant effect. Recent studies have shown that this substance can effectively remove toxic substances from the body. However, ACC is most often used for wet and dry coughs to facilitate sputum discharge. This medication is able to thin thick mucus and then gently remove it from the respiratory organs. Among other things, acetylcysteine ​​has a mild anti-inflammatory effect.

ACC can be prescribed for the treatment of both adults and children of various ages. In the latter case, the required dose is calculated by the attending physician.

Indications

When taking ACC for a cough, you can notice a positive result just an hour after the initial dose. Most often, doctors prescribe granules for making a solution and original soluble tablets to patients with cough. Such medications are considered more convenient to use. You can start taking one or another form of the drug only on the recommendation of a doctor, since they have different effects on the respiratory organs.

Syrup with acetylcysteine ​​will quickly help eliminate cough in chronic lung pathologies, and a special solution for inhalation is very effective for laryngotracheitis.

The drug is prescribed by doctors for pathologies of the respiratory organs, which are accompanied by various types of cough, namely:

• bacterial and viral pneumonia;
• bronchitis of various types;
• cystic fibrosis and asthma;
• various types of sinusitis;
• otitis.

ACC for bronchitis and pneumonia is prescribed only as part of complex therapy. In this case, in addition to ACC, antibiotics and medications of other groups are often prescribed.

Most often, ACC is prescribed for a productive wet cough. This medication can also be used for unproductive coughs, but only if the patient has already taken medications to thin out too thick sputum. The viscous mucus in the respiratory organs has already liquefied, and the cough has become productive. Otherwise, ACC will have no effect on an exhausting dry cough.

For dry coughs, people are usually prescribed ACC Long, but only in combination with drugs that help thin the mucus.

When prescribing ACC for children with a dry cough, you should immediately tell the parents that the treatment will give a noticeable result if the drinking regime is observed, and in addition to this drug, the child will take syrups based on licorice root or medications containing ambroxol.

Contraindications

Not all cases can be treated with ACC. It is contraindicated to take the medication if:

• pulmonary hemorrhages;
• coughing up sputum mixed with blood;
• chronic renal failure;
• septic;
• hepatitis;
• special sensitivity to the ingredients in the drug.

During pregnancy and breastfeeding, the drug can be prescribed only in special cases when there is no alternative. In this case, the expected benefit for the expectant mother should be higher than the possible harm to the child.

Side effects

ACC may have certain side effects. When treated with this medication, there is a high likelihood of the following disorders:

• there may be persistent headaches and constant tinnitus;
• heartburn, constant nausea and bowel disorders;
• increased heart rate and decreased blood pressure.

The annotation for ACC Long contains information that there may be allergic reactions that look like a skin rash.

How to take the medicine

The dosage of ACC depends not only on the person’s age and the severity of the disease, but also on the type of drug. All types of ACC have a certain daily dosage.

ACC 100 can be given to children almost from birth. Children under 2 years of age are prescribed a medicine of 50 mg three times a day. A soluble 100 mg tablet is divided in half and then diluted in 0.5 cups of water.

From 2 to 5 years old, the child drinks the medicine 4 times a day, a single dose is 100 mg. Children over 6 years old drink ACC 200 three times a day.

ACC Long can be prescribed to patients over 14 years of age. The daily dose is 600 mg, taken at a time. The effervescent tablet is dissolved in water and drunk immediately after meals.

You need to understand that if the prepared medicine could not be drunk for some reason, then it should be taken no later than a couple of hours after dilution. If more time has passed, then prepare a fresh medicinal drink.

ACC 200 can only be taken in the form of an aqueous solution. It is prescribed to children who are already six years old. You can consume 2 sachets per day, which are previously diluted in warm water. Adolescents over 14 years of age and adult patients consume a whole sachet of pre-diluted drug three times a day.

The powder for the solution can be diluted in water, iced tea, your favorite juice or cooled compote. The powder for preparing the solution is poured with clean water up to the line marked on the bottle, and then mixed well, after closing the lid. After taking the medicine, be sure to drink enough water or other drink, in which case the effectiveness of the treatment will be higher.

If ACC does not help with cough at all for 4-5 days, then you need to consult a doctor; the dose may need to be adjusted. The minimum course of treatment is 5 days, but if necessary, therapy can last up to six months.

Infants can dilute ACC in water and then give it through a bottle with a nipple.

Features of treatment for pregnant women

During pregnancy, women's immunity is greatly reduced, which is why the incidence of respiratory infections increases. To treat pregnant women, doctors select medications that will not have a negative effect on the fetus. The effect of ACC on pregnant women has not yet been fully studied, but based on the fact that it is prescribed to infants, expectant mothers can also take this medicine. The dose of medication for this group of patients is determined by the doctor.

If alarming symptoms appear while taking the drug, stop treatment and contact a medical facility.

ACC is a highly effective remedy for wet and dry coughs, which can also be purchased at a low price. The form and dose of the medicine is selected by the doctor individually, but more often they prescribe soluble tablets and packaged powder for preparing a healing drink.

The composition of the drug ACC 200 includes the active ingredient acetylcysteine (200 mg), as well as additional components: sodium bicarbonate, citric anhydride, ascorbic acid, mannitol, sodium citrate, saccharin, lactose anhydride, flavoring.

Release form

ACC 200 is produced in effervescent tablets, white, round, flat, with a score line on one side. They have a blackberry aroma. Contained in packages of 4, 20, 25 pcs.

pharmachologic effect

The product has a mucolytic effect. Due to the fact that the structure of the molecule contains acetylcysteine ​​sulfhydryl groups, the disulfide bonds of acidic mucopolysaccharides of sputum are broken. As a result of this process, the viscosity of the mucus decreases. ACC 200 also demonstrates activity in patients with purulent sputum.

If acetylcysteine ​​is used for prophylactic purposes, in patients who suffer from cystic fibrosis and chronic , the severity and frequency of exacerbations decreases.

Pharmacokinetics and pharmacodynamics

After internal administration, the drug is rapidly absorbed. Metabolism in which the metabolite is formed - and other metabolites, passes through the human liver.

Bioavailability when taken internally is 10%, binding to plasma proteins is 50%. The highest concentration is observed after 1-3 hours. It is excreted in the urine, the half-life is 1 hour.

Indications for use

The use of ACC 200 is indicated in the following cases:

• for diseases of the respiratory system, if viscous sputum is formed, which is difficult to separate (acute / chronic / obstructive bronchitis, bronchiectasis, cystic fibrosis, pneumonia, , );

Contraindications

It is contraindicated to take tablets in the following cases:

• high sensitivity to acetylcysteine ​​or other drug ingredients;
• period of exacerbation ;
• pulmonary hemorrhage;
• hemoptysis;
• lactose intolerance, lactase deficiency;
• glucose-galactose malabsorption;
• child's age up to 2 years.

This medicine is used with caution in case of duodenal ulcer and a history of histamine intolerance. The medicine is also carefully prescribed to people with varicose veins of the esophagus, obstructive bronchitis, diseases of the adrenal glands, liver failure and, arterial hypertension .

Side effects

The following side effects may occur while taking the drug:

• nervous system: noise in ears, ;
• the cardiovascular system: decrease, ;
• digestion: , nausea, vomiting, ;
• allergic reactions: isolated manifestations – bronchospasm , skin rash;
• other reactions: isolated manifestations – bleeding.

Effervescent tablets ACC 200, instructions for use (Method and dosage)

The instructions for use of ACC 200 stipulate that the medicine, like the powder, is prescribed to patients over 14 years of age, 200 mg two to three times a day.

Patients from 6 to 14 years old take 1 tablet twice a day.

Children aged 2 to 5 years should take half a tablet of ACC 200 two to three times a day.

Patients with cystic fibrosis after 6 years are advised to take 1 tablet. 3 times a day, children under 6 years of age are prescribed the drug at the rate of 400 mg of acetylcysteine ​​per day. If the patient's weight exceeds 30 kg, the dose, if necessary, is increased to 800 mg per day.

If colds are being treated, the course of treatment lasts 5-7 days.

Before taking the medicine and after, you need to drink plenty of fluids to enhance the mucolytic effect of the drug. You need to take the drug after meals.

The method of diluting the tablets is the same as the method of using the powder. They need to be dissolved in half a glass of water and the solution should be drunk immediately.

Overdose

If an overdose of the drug occurs, nausea, stomach pain, , . No dangerous or severe manifestations have been observed so far.

Interaction

It should be borne in mind that when taking ACC 200 and other cough suppressants simultaneously, dangerous mucus stagnation may develop due to the fact that the cough reflex is suppressed. Therefore, such drugs must be combined carefully.

Acetylcysteine ​​may enhance vasodilatory effects if you take these drugs at the same time.

There is a synergism between acetylcysteine ​​and bronchodilators.

Acetylcysteine ​​is not compatible pharmaceutically with (penicillins, cephalosporins, ,) and proteolytic.

When taken simultaneously, acetylcysteine ​​reduces the absorption of tetracycline, cephalosporins, and penicillins. Therefore, you need to take such drugs at intervals of at least two hours.

If acetylcysteine ​​comes into contact with rubber or metals, sulfides are formed, which have a characteristic odor.

Terms of sale

ACC 200 can be purchased without a prescription.

Storage conditions

Keep away from children, away from moisture and light, store at a temperature of no more than 30 degrees. The tube should be tightly closed after removing the tablet.

Best before date

Store for 3 years.

special instructions

If ACC 200 is prescribed to patients with bronchial asthma and obstructive bronchitis, it is necessary to do this carefully and constantly monitor bronchial patency.

If any side effects develop, you should stop treatment and consult a doctor.

If necessary, dissolve the drug using glass containers.