Chloramine treatment instructions for use. Guidelines for the use of chloramine for disinfection purposes

CHLORAMIN B (Сhloraminum B)- the most famous and widely used disinfectant, it is a white or slightly yellowish crystalline powder with a faint odor of chlorine.
Soluble in water (1:20), more soluble in hot water. Dissolves in alcohol (1:25), forming cloudy solutions. Contains 25 - 29% active chlorine.
Chloramine solution acts as an antiseptic and deodorizing agent. It also has spermicidal properties. Also used for treatment infected wounds(rinsing, wetting tampons and napkins with a 1.5 - 2% solution), hand disinfection (0.25 - 0.5% solution), non-metallic instruments. For disinfection of care items and secretions for typhoid, paratyphoid, cholera and other infections intestinal group and at droplet infections(scarlet fever, diphtheria, influenza, etc.) use 1 - 2 - 3% solution, for tuberculosis infection - 5% solution.
Disinfection with Chloramine B are sometimes used with activated solutions by adding ammonia, sulfate or ammonium chloride, which increases the bactericidal properties of the solutions.
Store chloramine B in a well-closed container in a cool place, protected from light.

Consumption rate of Chloramine for ready-made solutions:

When applied to indoor surfaces (floors, walls, etc.), sanitary equipment (baths, sinks, etc.), sanitary transport, wipe with a rag soaked in a solution of the product, or irrigate with a hydraulic remote control, automax, or sprayer. The consumption rate of the product solution when wiping is 150 ml/m2 surface, when using a solution with detergent– 100 ml/m2, during irrigation – 300 ml/m2 (hydraulic control panel, automax), - 150 ml/m2 (Quasar type sprayer). The laundry is soaked in a container with a solution of the product at a consumption rate of 5 l/kg of dry laundry. Cover the container tightly with a lid. After disinfection is completed, the laundry is washed and rinsed. Tableware freed from food residues, laboratory dishes, and dishes containing secretions are completely immersed in the product solution. The solution consumption rate is 2 l. for 1 set of tableware.
Packing rate 15 kg (50 bags of 300.0 g each in a bag)

Shelf life: 5 years, non-activated solutions - 15 days, activated solutions of the product are used immediately after preparation.

WWW . DEZSREDSTVA . RU reference and information Internet catalog p. 21

INSTRUCTION No. 04/09

on the use of disinfectant

"Chloramine B 99.9"

(“Jiaxing Grand Corporation”, China)

in medical and preventive institutions, infectious foci, in public utility and trade enterprises, in transport, in children's institutions, education, culture, recreation, sports, penitentiary and social security

INSTRUCTION No. 04/09

on the use of disinfectant "Chloramine B 99.9"

(Jiaxing Grand Corporation, China)

in medical and preventive institutions, infectious foci, in public utility and trade enterprises, in transport, in children's institutions, education, culture, recreation, sports, penitentiary and social security

The instructions were developed: at the Testing Laboratory Center of the State Unitary Enterprise "Moscow City Disinfection Center" (SUE MGCD), the Testing Laboratory Center of the Federal State Institution "RNIITO named after. R.R. Vreden Rosmedtekhnologii"; FSUE "SSC Applied Microbiology" (FSUE "SSC PMB").

Authors: N.P. Sergeyuk., Yu.G. Suchkov, M.P. Munitsyna, M.A. Tarabrina, K.A. Shestakov, A.N. Kochetov (State Unitary Enterprise MGCD), A.G. Afinogenova, A.V. Semenov, M.A. Bichurina, N.P. Ovchinnikov (FSI "RNIITO named after R.R. Vreden Rosmedtekhnologii"); V.N. Gerasimov, M.V. Khramov (FGUN "SSC PMB").

1. General information.

1.1. Means "Chloramine B 99.9" is a white or slightly yellowish crystalline powder with a chlorine odor, containing active substance sodium salt of benzenesulfonic acid chloramide (99.9%, but not less than 99.5%). The content of active chlorine in the product is not less than 25.0%. Solubility in water is not less than 20 g / 100 ml.

It is used in the form of activated, non-activated solutions and powder.

The shelf life of the product in unopened manufacturer's packaging is 6 years; The shelf life of non-activated solutions is 15 days (if stored in a cool, dark place in a closed container). Activated solutions of the product are used immediately after preparation.

1.2 Remedy "Chloramine B 99.9" has antimicrobial effect against bacteria (including Mycobacterium tuberculosis), viruses, fungi of the genus Candida, dermatophytes, pathogens of particularly dangerous infections - anthrax, plague, cholera, tularemia.

1.3.Remedy "Chloramine B 99.9" according to the parameters of acute toxicity according to GOST 12.1.007-76 it belongs to class 3 moderately hazardous substances when administered into the stomach, class 4 low-hazard substances when applied to the skin and according to the degree of volatility, moderately toxic when administered parenterally, has a local irritant effect on the skin and a pronounced effect on the mucous membranes of the eyes; has a sensitizing effect.

Working solutions in the form of vapors do not cause irritation to the respiratory system, with a single exposure they do not have a local irritating effect on the skin, with repeated exposures they cause dryness and flaking of the skin, and if they come into contact with the eyes they cause mild irritation.

When used by irrigation, working solutions, as well as activated solutions, cause severe irritation to the respiratory system and eyes.

The maximum permissible concentration of chlorine in the air of the working area is 1 mg/m3.

1.4. Means "Chloramine B 99.9" intended for:

Disinfection of indoor surfaces, hard furniture, sanitary equipment, rubber mats, shoes made of plastic and rubber, linen, dishes, toys, patient care items, medical products, medical waste, including dressings (cotton-gauze bandages, tampons etc.), linen and products medical purposes single use; cleaning material, secretions from bacterial infections (including tuberculosis) and viral etiology, candidiasis and dermatophytosis, especially dangerous infections (anthrax, plague, cholera, tularemia) when carrying out final, current and preventive disinfection in infectious foci, medical institutions, in clinical, microbiological, virological laboratories, children's institutions, on sanitary transport,

Carrying out general cleaning in medical and preventive care and children's institutions;

Preventive disinfection at communal facilities (hotels, hostels, hairdressers, public toilets), cultural, recreational, sports institutions (sports and cultural-health complexes, swimming pools, cinemas, offices, etc.), sanitary checkpoints, social security institutions and penitentiary institutions; catering and trade enterprises,

Applications by the population in everyday life.

2. Preparation of working solutions

2.1. Means "Chloramine B 99.9" used in the form of non-activated and activated solutions with ammonium salts or ammonia.

2.2. Working solutions of the product are prepared in enamel, glass or polyethylene containers by stirring the powder in water until completely dissolved in accordance with the calculations given in tables 1 and 2.

Table 1

Preparation of non-activated solutions of the product "Chloramine B 99.9"

Note: for more rapid dissolution products should use heated water

up to 50-60 0 C.

To give cleaning properties to working solutions of the product "Chloramine B 99.9" You can add synthetic detergents approved for use in medical institutions in an amount of 0.5% (5 g/l of solution or 50 g/10 l of solution).

2.3. Activated solutions of the product are prepared by adding an activator (one of the ammonium salts - ammonium chloride, sulfate, ammonium nitrate or ammonia) to its working solutions. The ratio of the amount of ammonium salt and the amount of active chlorine in the working solution is 1: 2, and the ratio of ammonia and the amount of active chlorine is 1: 8. Activated solutions are used immediately after preparation. When preparing activated solutions of the product "Chloramine B 99.9" use the calculations given in table. 2.

table 2

Preparation of activated solutions of the product "Chloramine B 99.9"

3. Using ChloramineB99.9"

3.1. Solutions of the product are used to disinfect indoor surfaces (floors, walls, doors, hard furniture, etc.), sanitary equipment (bathtubs, sinks, etc.), rubber mats, cleaning materials, linen, tableware, laboratory utensils, and tableware. for secretions, toys, patient care items, medical products made of corrosion-resistant metals, glass, plastics, rubber, secretions (sputum, feces, etc.), sanitary transport.

It is allowed to use solutions of the product "Chloramine B 99.9" with the addition of synthetic detergents approved for use in medical institutions in an amount of 0.5% (5 g/l solution or 50 g/10 l solution).

Disinfection of objects is carried out by wiping, irrigation, immersion, soaking and falling asleep. Modes for disinfecting objects with solutions of the product "Chloramine B 99.9" are given in table. 3-12.

3.2. Indoor surfaces (floors, walls, etc.), sanitary equipment (baths, sinks, etc.), ambulance vehicles are wiped with a rag soaked in a solution of the product or irrigated with a hydraulic remote control, Automax, or Quasar-type sprayer. The consumption rate of the product solution when wiping is 150 ml/m2 of surface, when using a solution with detergent - 100 ml/m2, when irrigation - 300 ml/m2 (hydropult, automax), - 150 ml/m2 (spray type "Quasar"). After disinfection is completed, sanitary equipment is washed with water and the room is ventilated.

3.3. The laundry is soaked in a container with a solution of the product at a consumption rate of 5 l/kg of dry laundry. Cover the container tightly with a lid. After disinfection is completed, the linen is washed and rinsed.

3.4. The cleaning material is soaked in a solution of the product, after disinfection is completed, rinsed and dried.

3.5. Tableware freed from food residues, laboratory dishes, and dishes containing secretions are completely immersed in the product solution. The solution consumption rate is 2 liters per 1 set of tableware. The container is closed with a lid. After disinfection, the dishes are washed with water until the smell of chlorine disappears.

3.6. Disinfection of patient care items and toys is carried out by irrigation, wiping or immersion in a solution of the product. After disinfection is completed, they are washed with water until the smell of chlorine disappears.

3.7. Rubber mats are disinfected by wiping with a rag soaked in a solution of the product, or by immersing in a solution of the product. Shoes made of plastic and rubber are immersed in the product solution, preventing them from floating. After disinfection is completed, they are washed with running water and dried.

3.8. Disinfection of medical devices is carried out in plastic or enamel (without damaging the enamel) containers, closed with lids.

Medical products, immediately after their use, are completely immersed in a container with a solution of the product, filling the channels and cavities of the products with the help of auxiliary means (electric pumps, syringes, pipettes), while removing air bubbles. Detachable products are processed in disassembled form. Products with locking parts are immersed open, having previously made several working movements with them in the solution for better penetration of the solution into hard-to-reach areas of the products. The thickness of the layer of product solution above the products must be at least 1 cm.

After disinfection, metal and glass products are washed under running water for 3 minutes, and rubber and plastic products - for at least 5 minutes.

3.9. The sputum collected in a container is poured with a solution of the product (at a ratio of 1 part sputum: 2 parts solution) and mixed thoroughly.

3.10. Liquid secretions and feces infected with bacteria of especially dangerous infections are disinfected by adding (dissolving) powder of the product in a ratio of 10:1 (volume/weight), thoroughly mixing and subsequent exposure for 120 minutes. When infected liquid discharge and feces with anthrax spores, they are filled with a 10.0% activated solution of the product in a ratio of 1:1 (volume/weight), mixed thoroughly and kept for 120 minutes.

3.11. Disinfection (neutralization) of medical waste of classes B and C of medical institutions, including infectious diseases departments, dermatovenerological, TB and mycological hospitals, as well as laboratories working with microorganisms of pathogenicity groups 1-4 (including especially dangerous infections), is carried out taking into account the requirements of Sanitary rules and regulations SanPiN 2.1.728-99 “Rules for the collection, storage and disposal of waste from medical institutions.”

Used dressings, napkins, cotton swabs, single-use underwear are immersed in a separate container with product solutions. Upon completion of disinfection, the waste is disposed of.

Disinfection of single-use medical devices is carried out in plastic or enameled (without damaging the enamel) containers, closed with lids. When disinfecting, products are completely immersed in the product solution. Detachable products are immersed in the solution in disassembled form. Products with locking parts are immersed open, having previously made several working movements with them in the solution for better penetration of the solution into hard-to-reach areas of the products. During soaking (disinfection soaking), the channels and cavities must be filled (without air pockets) with a solution. The thickness of the mortar layer above the products must be at least 1 cm.

After disinfection is completed, the products are removed from the container with the solution and disposed of.

Containers for the collection and disposal of medical waste are treated by wiping according to the appropriate infection regimes.

3.12. Disinfection regimes for various objects in outbreaks of cholera and tularemia are given in Table 10.

3.13. Disinfection regimes for various objects in plague foci are given in Table 11.

3.14. Disinfection regimes for various objects in anthrax outbreaks are given in Table 12.

3.15. When carrying out general cleaning in medical-prophylactic and children's institutions, they are guided by the regimes presented in table. 13.

3.16. Sanitary transport for transporting infectious patients is treated in the regimes recommended for the corresponding infections, and for infections of unknown etiology - in the regimes recommended for viral infections(Table 5). Regular preventive treatment of sanitary transport is carried out according to the regimes presented in Table 3.

3.17. In hotels, hostels, clubs and other public places, various objects are disinfected according to the regimes indicated in Table 3.

3.18. In bathhouses, hairdressing salons, swimming pools, sports complexes, sanitary inspection rooms, when carrying out preventive disinfection, the treatment of objects is carried out according to the regimes recommended for dermatophytosis (Table 9).

3.19. In everyday life, the product is used in accordance with the household label.

Table 3

Modes for disinfecting objects with non-activated solutions of the product
"Chloramine B 99.9" for bacterial (except tuberculosis) infections

(BCB) is a white or slightly yellowish powder with a faint odor of chlorine. Contains up to 30% active chlorine. It can be stored at home for years without reducing its activity. Unlike bleach, chloramine does not destroy fabrics and paints.

For use in the form of a solution of 0.2% -10% concentration for disinfection of brushes, tableware, etc.

Preparation of the solution

To prepare chloramine solutions, the following quantities of the drug are required:

Precautions when working with chloramine

When working with chloramine and especially its activated solutions, it is necessary to protect the respiratory system with a RU-60 respirator. The work is performed in a robe, rubber gloves, and an apron. Guidelines developed at the All-Union Scientific Research Institute of Disinfection and Sterilization. The instructions for the use of chloramine for disinfection purposes dated December 24, 1947, from the moment these guidelines were approved, shall be considered no longer in force.

General information

Chloramines include a number of organic compounds, having a common chemical formula RSO 2 NH 2 (R - means radical), in which one or both hydrogen atoms located at nitrogen are replaced by chlorine. A distinction is made between chloramine B, if the starting product is benzene, and chloramine T, if toluene is used for this.

Domestic chloramine used for disinfection purposes is called chloramine B, belongs to the group of monochloramines and has the formula: C 6 H 5 SO 2 N(Na)C1*3H 2 . He is sodium salt benzene sulfonic acid chloramide, has the form of a white fine-crystalline powder. Typically contains 26% active chlorine, maintaining this amount of chlorine for a long time at proper storage.

Chloramine B is highly soluble in water at room temperature. Its solutions do not spoil or discolor fabrics.

Chloramine has high activity against gram-negative and gram-positive microorganisms, starting from 0.2%. Since active chlorine binds with organic substances, the concentration of solutions under practical conditions is increased to 0.5-1-2-3-5%. Hot solutions of chloramine have a higher disinfecting effect.

The bactericidal and virucidal properties of chloramine solutions are increased by the addition of ammonium compounds (ammonia, ammonium sulfate or ammonium chloride), which act as an activator. Activated chloramine solutions quickly lose active chlorine, so they are used immediately after preparation.

Chloramine is stored in a dark glass container with a well-fitted stopper or, even better, with a ground-in stopper, in a wooden container or in a tin container coated on the inside with asphalt varnish, as well as in polyethylene bags. When storing chloramine, avoid direct exposure to light and moisture.

Chloramine and solutions prepared from it are checked from time to time for the content of active chlorine in them; This establishes the loss of active chlorine and the correct preparation and storage of solutions.

Find something else interesting:

CHLORAMINE B

Name (Latin)

Composition and release form

It is the sodium salt of benzenesulfonic acid chloramide, available in the form of a white to light yellow crystalline powder with a faint odor of chlorine. The content of active chlorine in the product should be in the range from 24% to 27%. Produced in plastic bags of 100 - 500 g, transport packaging - bags up to 30 kg.

Pharmacological properties

The drug has an antimicrobial effect against bacteria (including Mycobacterium tuberculosis), viruses (including HIV) and parenteral pathogens viral hepatitis), fungi of the genus Candida, dermatophytes, pathogens of particularly dangerous infections - anthrax, plague, cholera. According to the parameters of acute toxicity, according to GOST 12.1.007-76 it belongs to class 3 of moderately hazardous substances when introduced into the stomach, moderately toxic when parenteral administration, low-hazard in terms of volatility, in powder form has a pronounced local irritant effect on the skin and mucous membranes of the eyes and a weak sensitizing effect, carcinogenic and cocarcinogenic effects have not been detected.

Indications

For disinfection of indoor surfaces, sanitary equipment, linen, dishes, toys, patient care items, medical products, cleaning materials for bacterial (including tuberculosis) and viral infections (including hepatitis with parenteral transmission and HIV infection ) etiology, dermatophytosis, candidiasis, especially dangerous infections (anthrax, plague, cholera) during final, current and preventive disinfection in infectious foci, medical institutions, children's institutions, communal facilities, enterprises Catering, in everyday life, during general cleaning in medical and preventive care and children's institutions.

Doses and method of administration

For disinfection - used in the form of non-activated and activated solutions with ammonium salts or ammonia in a concentration of 0.5 - 5%. Working non-activated solutions are prepared by stirring it in water until completely dissolved in accordance with the calculations given in the table:

The time for disinfecting objects with non-activated solutions of Chloramine B for infections of bacterial (except tuberculosis) etiology ranges from 0.5 to 5 hours, depending on the object and the method (wiping or irrigation, immersion or soaking) of disinfection. For household disinfection: dissolve 4 tablespoons (50 g) in 5 liters of water. Use the resulting solution to treat indoor surfaces (floors, walls, doors, etc.). Wipe sanitary equipment (baths, sinks, toilets, etc.) twice with a rag soaked in the product solution. Immerse dishes, toys, patient care items, and linen in the solution for 60 minutes. To disinfect linen contaminated with secretions and cleaning material, use a solution prepared at the rate of 2 tablespoons of product per 1 liter of water. After treatment, rinse linens and cleaning materials, wash dishes, toys, and care items with running water until the smell of chlorine disappears.

Side effects

If the rules are followed, no dilutions are observed.

Contraindications

Increased sensitivity to the drug.

special instructions

Avoid contact of product with eyes and skin. Carry out all work with rubber gloves.

Storage conditions

In a cool, dry, dark place, out of reach of children, away from medicines, food and petroleum products, explosives and flammable substances. Shelf life: 5 years. The shelf life of non-activated solutions is 15 days (if stored in a cool, dark place in a closed container). Activated solutions are used immediately after preparation.

I APPROVED
Head of the Main Sanitary and Epidemiological Directorate of the USSR Ministry of Health
V. E. KOVSHILO
October 21, 1975

METHODOLOGICAL INSTRUCTIONS
ON THE USE OF CHLORAMINE FOR DISINFECTION PURPOSES

I. General information

1. Chloramines include a number of organic compounds having the general chemical formula RSO2NH2 (R means radical), in which one or both hydrogen atoms located at nitrogen are replaced by chlorine. They are distinguished if the starting product is benzene, and chloramine T if toluene is used for this.

2. Domestic chloramine used for disinfection purposes is called chloramine B, belongs to the group of monochloramines and has the formula: C6H5SO2N(Na)Cl x 3 H2O. It is a sodium salt of benzene sulfonic acid chloramide and has the appearance of a white fine-crystalline powder (sometimes yellowish tint). Typically contains 26% active chlorine, retaining this amount of chlorine for a long time if properly stored (loss of active chlorine during the year does not exceed 0.1%).

3. Chloramine B is highly soluble in water at room temperature. Its solutions retain active chlorine for 15 days and can be prepared for future use. They do not spoil or discolor fabrics.

4. Chloramine has high activity against gram-negative and gram-positive microorganisms, starting from 0.2%. Since active chlorine binds with organic substances, the concentration of solutions under practical conditions is increased to 0.5-1-2-3-5%. Hot solutions of chloramine (50-60°) have a higher disinfecting effect.

5. The bactericidal and virucidal properties of chloramine solutions are increased by the addition of ammonium compounds (ammonia, ammonium sulfate or ammonium chloride), which act as activators. Activated chloramine solutions quickly lose active chlorine, so they are used immediately after preparation.

6. Store chloramine in a dark glass container with a well-fitted stopper or, even better, with a ground stopper, in a wooden container or in a tin container coated on the inside with asphalt varnish, as well as in polyethylene bags. When storing chloramine, avoid direct exposure to light and moisture.

7. Chloramine and solutions prepared from it are checked from time to time for the content of active chlorine in them; This establishes the loss of active chlorine and the correct preparation and storage of solutions.

II. Preparation of chloramine solutions

8. Working solutions of chloramine are prepared by stirring it until completely dissolved in water, preferably heated to 50-60°.

9. To prepare chloramine solutions, the following quantities of the drug are required:

10. Activated solutions of chloramine are prepared by diluting, first of all, a weighed amount of chloramine in cold or hot (50-60°) water until completely dissolved, followed by adding an activator (ammonium chloride, sulfate, ammonium nitrate) in an amount equal amount active chlorine in solution, and 8 times less ammonia is added. Activated chloramine solutions are used immediately after preparation.

11. To prepare 1 or 10 liters of activated solution you need:

III. Application of chloramine solutions

12. Solutions of chloramine in different concentrations used for disinfection of intestinal and droplet infections of bacterial and viral etiology, tuberculosis, and fungal diseases.

14. For these infections, chloramine solutions are used for wiping or irrigating surfaces and soaking disinfected objects, as well as in some cases, for filling selections.

Disinfection regimes for various objects for the listed infections are presented in Table. 1-5.

Table 1

REGIMES FOR DISINFECTION WITH CHLORAMINE OBJECTS IN FOCI OF INTESTINAL AND DROPLET INFECTIONS OF BACTERIAL ETIOLOGY

table 2

REGIMES FOR DISINFECTION OF OBJECTS IN FOIMS OF MICROSPORIA, TRICHOPHYTIA AND FAVUS

Table 3

REGIMES FOR DISINFECTION OF OBJECTS IN FOIMS OF VIRAL HEPATITIS AND ENTEROVIRAL INFECTIONS

Table 4

REGIMES FOR DISINFECTION OF OBJECTS WITH ACTIVATE SOLUTIONS OF CHLORAMINE IN FOCI OF TUBERCULOSIS

Note: According to the instructions for carrying out current and final disinfection for tuberculosis N 744-68, the use of non-activated chloramine solutions in foci of tuberculosis is not recommended.

Table 5

MODES FOR DISINFECTION OF OBJECTS WITH ACTIVATE SOLUTIONS OF CHLORAMINE FOR ANTHRAX

IV. Precautions when working with chloramine

When working with chloramine, and especially its activated solutions, it is necessary to protect the respiratory system with a RU-60 respirator. The work is performed in a robe, rubber gloves, and an apron.

The instructions for the use of chloramine for disinfection purposes dated December 24, 1947, from the moment these guidelines were approved, shall be considered no longer in force.