What pills can be used to treat reflux? Effective methods of treating esophagitis. Possible treatment regimens

In the treatment of gastroesophageal reflux disease, antacids, histamine receptor blockers, proton pump inhibitors and prokinetic drugs are used.

The use of a specific group of drugs depends on the age of the patient, the stage of the pathological process, and the severity of symptoms. Next we will describe how to treat reflux esophagitis and what pills the doctor prescribes.

Antacids

– a group of drugs whose purpose is to neutralize excess acidity of gastric juice through chemical reactions. Most modern drugs contain magnesium, calcium, and aluminum in the form of chemical compounds. The mechanism of action is based on these substances.

In addition to the main components, the composition may contain excipients that have the following effects:

  • laxative;
  • antispasmodic;
  • anesthetic (anaesthetic) and others.

Antacids are classified on the:

  • absorbable (systemic);
  • non-absorbable (non-systemic).

The difference between them is that systemic ones have the ability to be absorbed into the blood, while non-systemic ones do not.

Systemic antacids

These drugs are also used for reflux esophagitis. Their positive side is the speed of onset of the therapeutic effect; patients note the elimination of heartburn within a few minutes.

On the other hand, the effect of using these drugs is quite short-lived. In addition, gastroenterologists describe the phenomenon of rebound after discontinuation of absorbable drugs. It consists in the fact that when the intake of the active substance into the body is stopped, the synthesis of hydrochloric acid (HCl) by the parietal cells of the stomach increases.

Another disadvantage is the formation of carbon dioxide during the chemical neutralization of hydrochloric acid. This leads to distension of the stomach, which provokes new gastroesophageal reflux.

Excessive absorption of the active substance into the blood can cause a shift in the acid-base balance towards alkalization (alkalosis).

Among the drugs in the group of non-systemic antacids are:

  • Rennie;
  • Bourget mixture;
  • sodium bicarbonate;
  • calcium carbonate;
  • magnesium oxide and others.

With long-term use of calcium-containing products, constipation and the formation of kidney stones may occur, and when combined with dairy products, nausea, vomiting, and bloating may occur.

Non-systemic antacids

They differ from systemic ones in the slower onset of the therapeutic effect. However, the non-absorbable group lasts much longer than the absorbed drugs.

Non-systemic drugs do not have the rebound phenomenon, do not form carbon dioxide when neutralizing hydrochloric acid, and generally have fewer side effects.

According to their composition, they are divided into:

  • containing aluminum phosphate (Phosphalugel);
  • magnesium-aluminum products (Alumag, Almagel, Maalox);
  • calcium-sodium (Gaviscon);
  • containing aluminum, magnesium, calcium (Talcid, Rutacid).

In addition, there are combination medications, the most popular of which are magnesium-aluminum combinations. Almagel A includes anesthesin, which adds an analgesic effect to the drug.


Simethicone is also added to the main substance, which is used in the treatment of bloating (flatulence). Such remedies include Gestid, Almagel Neo. Other drugs are also used to treat reflux esophagitis in adults.

Histamine receptor blockers

Histamine (H2) receptor inhibitors have the ability to suppress the secretion of hydrochloric acid by the parietal cells of the stomach. This is a fairly old group of drugs, which is now used only in certain categories of patients.

This is due to the fact that they cannot provide 100% control over the production of hydrochloric acid, since its production, in addition to histamine, is also regulated by gastrin and acetylcholine. Also, H2 blockers have the rebound phenomenon, which was described above.

In addition, the effect of their use decreases with each repeated dose (tachyphylaxis). Tachyphylaxis appears on the third day of daily use of the medicine. As a result, histamine receptor blockers cannot be used for very long-term treatment of reflux esophagitis.

It is worth noting that the above phenomena manifest themselves in each person individually.

There are several generations of this group:

The most effective drug Based on the degree of inhibition of hydrochloric acid secretion, Famotidine (trade name Kvamatel) is considered. The relatively low incidence of side effects and economic factors also support it.

3rd generation drugs may be indicated for the treatment of gastroesophageal reflux disease in patients who do not experience tachyphylaxis.

Proton pump inhibitors

What other medications help with reflux esophagitis? Proton pump blockers (PPIs, Na/KATPase inhibitors) are a group of drugs aimed at inhibiting the secretion of HCl (hydrochloric acid) by acting on the parietal cells of the stomach. Unlike H2 blockers, PPIs allow complete control of secretion through dosage adjustment.

PPIs are considered effective and are used in gastroduodenitis with high acidity, peptic ulcer of the duodenum and stomach.

When taken orally, the active substance of the drug dissolves into the bloodstream, then into the liver, after which it enters the membranes of the main cells of the gastric mucosa. Further, as a result of complex physicochemical interactions, cells stop secreting hydrochloric acid, thereby reducing the acidity level (PH) of gastric juice.

There are up to 7 generations of PPIs, but they are all identical in their mechanism of action, differing only in the speed of onset of the effect (slightly) and the speed of elimination of the active substance from the body.

The most famous and the most commonly used PPI drug is Omeprazole(Omez). It belongs to the first generation of proton pump inhibitors and is considered the best in terms of price-quality ratio.

There are also widespread drugs for reflux esophagitis, such as:

In case of long-term use of large dosages, the risk of fractures of the limbs and spine increases, and there is a risk of developing hypomagnesemia (decreased magnesium levels in the blood).

Prokinetics

Prokinetics are a group of drugs that normalize gastrointestinal motility. They are divided into several subgroups according to their mechanism of action, but the most popular are representatives of dopamine receptor blockers (D2).

In the treatment of gastroesophageal reflux disease, they are used due to their ability to eliminate pathological reflux of gastric contents into the esophagus, and prokinetics generally have a positive effect on the peristalsis of the stomach and intestines.

A representative of the first generation is Metoclopramide (Cerucal), it is also classified as an antiemetic. This is a fairly old medicine, which is gradually fading into the background after the advent of the 2nd generation of prokinetic agents ( Domperidone, Domrid, Motilium).

The difference between the first and second generations is that the latter have fewer side effects. This is achieved due to the fact that 2nd generation dopamine receptor blockers have the ability not to penetrate the blood-brain barrier. Therefore, they do not cause spasms of the muscles of the face and eyes, protrusion of the tongue and others. Also, the 2nd generation practically does not provoke fatigue, headaches, weakness, or noise in the head.

How to treat reflux esophagitis? Drugs Itopride (Itomed, Primer) also included in the subgroup of D2 receptor blockers, but in addition it is capable of inhibiting acetylcholinesterase. This increases the amount of the mediator acetylcholine, which is necessary to improve gastrointestinal motility.

Antibiotics and vitamins in the treatment of GERD

Antibacterial drugs, that is, antibiotics, are not prescribed for reflux esophagitis. Their target is bacteria that cause an inflammatory response. In the case of GERD, inflammation is caused only by the reflux of acidic stomach contents into the alkaline environment of the esophagus.

Macrolide antibiotics(Azithromycin, Clarithromycin), which are used for the eradication of Helicobacter pylori (type B gastritis, peptic ulcer) have a positive effect on gastric motility, reducing the number of gastroesophageal refluxes. But their use is not indicated in the treatment of reflux esophagitis.


Vitamins for reflux esophagitis

Multivitamin complexes may be prescribed ( Duovit, Aevit, Vitrum, Multi-Tabs). Their use helps prevent hypovitaminosis and increase the protective and regenerative functions of the body.

Useful video: tablets for reflux esophagitis

Treatment regimen

When treatment is carried out for reflux esophagitis, what medications to take - we figured it out, now it is important to know how to do it. The frequency of administration, dosage and choice of medications is carried out by the attending physician after a face-to-face consultation. Self-medication can lead to a worsening of the disease, a decrease in quality of life, and irreversible consequences.

To eliminate the neutralization of hydrochloric acid in the first few days, systemic ( Rennie) or non-systemic antacid drugs ( Phosphalugel, Almagel). In case of intense pain, it is more rational to use Almagel A.

From the first day, the use of proton pump inhibitors is indicated ( Omeprazole, Omez) course for 4-6 weeks. During this period, the doctor adjusts the dose, selecting the optimal minimum dosage for a particular person. It is worth noting that PPIs are considered the main component of treatment for GERD in adults.

The last link is prokinetic drugs ( Domperidone) course for several weeks to reduce the number of gastroesophageal refluxes.

In some cases, the use of H2 blockers is allowed ( Famotidine) instead of proton pump inhibitors. This is basic information on the topic of treatment of reflux esophagitis, the most effective medications.

Reflux esophagitis is a disease that requires mandatory comprehensive drug treatment, which includes lifestyle adjustments, maintaining a therapeutic diet, and the use of medications and remedies prepared according to traditional recipes. In severe cases of the disease, surgery is prescribed. When prescribing treatment for reflux esophagitis, the gastroenterologist selects the drugs, relying on data on the causes and symptoms of the disease.

The duration of treatment for reflux esophagitis depends on its form. Therapy of the non-erosive form lasts 4 weeks. What medications to prescribe and in what dosage is decided by a specialist depending on the stage of the disease. In addition to drug therapy, it is possible to take decoctions and infusions of herbs and diet therapy. For the erosive form, treatment increases to 8 weeks and includes the use of hydrochloric acid production blockers, healing and hemostatic (if necessary) substances.

In case of complications, concomitant diseases or old age, the patient undergoes therapy for up to 12 weeks. If treatment is successful, prophylactic use of medications is recommended to achieve remission within six months.

Treatment regimens

  1. One drug is prescribed, without taking into account the symptoms and complexity of the disease. This scheme is not beneficial and in most cases has no effect.
  2. The second method involves following a certain diet and using antacids. Depending on the stage of inflammation, substances of varying effectiveness are prescribed.
  3. The third method is based on the primary relief of symptoms by taking proton pump blockers. The second priority is to take prokinetic medications.

The classic scheme consists of four stages, depending on the stage of tissue damage:

  • In the first degree, with mild symptoms, it is recommended to take prokinetic drugs and antacids.
  • The second degree requires maintaining a healthy diet and includes the use of acid blockers.
  • In cases of severe inflammation, proton pump inhibitors, H-2 blockers and prokinetics are prescribed.
  • The fourth degree cannot be treated with medication and requires surgical intervention.

Medicines used for treatment

Therapy for inflammation of the esophagus involves the use of several groups of drugs. At different stages of the disease, medications are used comprehensively in different combinations and dosages.

Prokinetics

The active substance affects the muscular activity of the digestive organs and normalizes the tone of the esophageal sphincter. Restoring the normal functioning of the esophagus promotes the rapid movement of food and helps cleanse the mucous membrane. This group includes Itopride, Domperidone, Motilium. The latter is prescribed in the presence of vomiting and nausea. Ganaton helps relieve symptoms in a week, heals in three weeks and has no side effects.

Proton pump inhibitors

Drugs that help reduce the production of hydrochloric acid by mucosal cells. They are used to relieve severe symptoms of inflammation and relieve pain. Fast-acting substances with minimal side effects.

The course of therapy is prescribed by a specialist, since long-term use can lead to bone fragility and affect kidney function. The main drugs included in the group: Omeprazole, Lansoprazole, Pantoprazole.

N-2 blockers

They have a similar effect to PPIs, the action occurs due to the blocking of histamine receptors. The production of hydrochloric acid is suspended, which makes it possible to alleviate the condition of the esophagus and stomach.

The fifth generation of such medicines has been developed. The most effective are Ranitidine and Famotidine. Abrupt cessation of use can lead to a short-term increase in symptoms of the disease.

Alginates and antacids

For esophagitis, for successful treatment, medications are prescribed that neutralize the effect of acid on the esophagus. Antacids are recommended to be taken in liquid form. The duration of the medicine is 10-15 minutes. The course of therapy is a maximum of two weeks, since the products contain magnesium and aluminum. This group includes Phosphalugel, Almagel, Maalox.

Alginates have a milder effect, so they are prescribed during pregnancy. The composition includes alginic acid, which after administration forms a protective layer on the surface of the mucosa.

Cytoprotectors

Increases the degree of protection of the mucous layer of the esophagus and stomach during. The tablets help improve blood flow, increase the secretion of protective mucus, lower acidity levels, and promote the healing of erosion sites. The most well-known drugs are Misoprostol and Dalargin.

Use of antibiotics for esophagitis

For the phlegmous type of esophagitis, antibiotics are prescribed to relieve inflammation in adult patients and relieve pain. With prolonged therapy, it can develop, so it is recommended to take antifungal agents together.

Use of other medications

Ursosan reduces the possibility of tissue damage from gastric juice due to the destruction and removal of bile acids. Trimedate helps reduce reflux and increases the rate at which food passes through the esophagus.

Symptomatic therapy

If reflux developed against the background of another disease or the pathology appeared as a complication of esophagitis, symptomatic treatment is carried out:

  • For neurological and psychological problems, it is necessary to consult a doctor of the required profile. Sedatives, etc. may be prescribed.
  • For gastric ulcers, antibacterial drugs are prescribed. De Nol helps neutralize the effect of Hilicobacter pylori, improves blood circulation in the walls of the stomach, and alleviates unpleasant signs of the disease.
  • When immunity decreases, immunomodulators are prescribed.

Therapy also includes the use of vitamin complexes with a high content of macroelements to improve the general condition of the body.

Treatment approaches

Depending on the stage of tissue damage, the presence of complications, etc., a suitable treatment method is selected.

The first involves taking medications for esophagitis of varying activity in several stages:

  1. Maintaining a therapeutic diet and using antacids.
  2. Use of H-2 blockers or prokinetic drugs.
  3. Comprehensive use of PPIs and prokinetics.

The second technique is carried out in three approaches:

  1. Prescribed to relieve symptoms.
  2. Taking inhibitors for five days to relieve discomfort.
  3. Use tablets only during exacerbation of the disease.

The third technique consists of:

  1. For minor inflammation, a short-term course of antacids or acidity blockers and adherence to nutrition and diet.
  2. For the treatment of stage II, a long course of PPIs or acid blockers and prokinetics. Diet therapy is also indicated.
  3. Stage III requires the use of a complex of blockers and PPIs or prokinetics. Instructions for use show the maximum permitted doses.
  4. If previous prescriptions have not brought any effect, surgical intervention is necessary.

Maintenance therapy

Drug treatment of esophagitis is the most effective. After undergoing therapy, it is necessary to adhere to a certain lifestyle and undergo a six-month course of maintenance treatment for reflux.

Using maintenance therapy, following a diet, changing your regimen and some habits, and using traditional medicine will help avoid relapse and the disease will not cause inconvenience in the future.

Reflux esophagitis is an inflammation of the esophageal mucosa due to the backflow of stomach and duodenal contents into it. Prescribing adequate treatment is important to prevent dangerous complications.

Symptoms associated with reflux cause serious discomfort to the patient and significantly impair the quality of life. With reflux, not only heartburn and pain occur, but also the risk of developing adenocarcinoma of the esophagus.

Signs of reflux esophagitis

Gastric juice has a low pH value, which indicates that it is acidic. Its entry into the alkaline environment of the esophagus causes symptoms of pain and discomfort in the area of ​​the xiphoid process or epigastrium.

Reflux disease manifests itself with frequently recurring symptoms:

  • Heartburn after eating, especially after eating fatty or hot foods, coffee and alcoholic drinks.
  • Sour belching or regurgitation of air, feeling of nausea.
  • Lump in throat, difficulty swallowing.
  • Chest pain after eating.

Symptoms of this disease are noticeably worse when a person lies down after eating.

Principles of treatment

The causes of reflux and its treatment are inextricably linked, and therapy should be comprehensive:

  • First of all, the mode of physical activity and nutrition are normalized. It is necessary to eat meals fractionally and in small volumes.
  • The next component of therapy is the use of medications that reduce the severity of symptoms. Their reception is carried out situationally. For example, for heartburn, patients are prescribed tablets and suspensions with an antacid effect (Phosphalugel, Almagel, Maalox, etc.).
  • There are medications used for basic treatment. Reflux esophagitis requires the prescription of antisecretory drugs (Omeprazole, Pantoprazole, etc.). Gastroenterologists recommend taking prokinetics (Cerucal, Domperidone).
  • The doctor with esophagitis due to reflux should also try to cure the accompanying imbalance of intestinal microflora. For this, probiotics and eubiotics are used, for example Hilak forte.

These medications should be taken for no more than two weeks. These medications are taken frequently during the day: up to 3-4 times. This is due to the fact that the therapeutic effect after taking the drug lasts no more than 4–6 hours.

For pain

In case of severe pain, you should take Almagel A with an anesthetic effect. This product has a more pronounced effect than just Almagel.

Medicines for pain relief and healing of mucous membranes with erosions: Drotaverine, Solcoseryl, sea buckthorn oil, Actovegin, pantothenic acid.

Sorbents

In the drug treatment of reflux esophagitis, it is necessary to use adsorbents. This group of drugs has a therapeutic effect by binding bile acids and other aggressive components of gastric or duodenal contents.

In addition, such drugs reduce the severity of clinical manifestations of esophageal reflux by forming a film-like substance. These medications should be taken according to the situation, but not longer than a week.

For nausea

In case of severe nausea and vomiting, the patient can be given Cerucal injections. An injection with this compound inhibits the vomiting center and eliminates unpleasant symptoms. The dose of the medicine is average therapeutic, according to the instructions for the drug.

Basic treatment, main course

After the symptoms of esophageal damage subside, doctors prescribe basic therapy. It includes the use of antisecretory drugs. These drugs are effectively used for long-term treatment of pathology.

Reflux esophagitis can occur in two ways.

  1. With the formation of erosions.
  2. No mucosal defects.

Regardless of the form, reflux esophagitis should be treated with antisecretory agents. They are aimed at reducing acid formation in the stomach. The aggressive factor becomes weaker, the symptoms are eliminated, conditions are created for the healing of the mucous membrane of the organ in the presence of erosive defects.

Let's talk about the drugs that are most often used to treat esophagitis. The first line is proton pump inhibitors. These include:

  • Rabeprazole;
  • Lansoprazole;
  • Pantoprazole;

Any of these drugs is effective and efficient in the fight against acid aggression.

To cure the erosive variant, it is necessary to take proton pump inhibitors at least twice a day. The dosage must be adequate. It depends on the presence/absence of erosions. For example:

  • Omeprazole should be taken twice a day (morning, evening) 20 mg.
  • Lansoprazole is prescribed 30 mg, taken twice a day.

The dosage and frequency of administration are chosen only by the doctor, depending on the situation!

The form of reflux esophagitis without the formation of mucosal defects requires the following use of medications:

  1. The course of treatment lasts for a month.
  2. Proton pump inhibitors are taken once a day.
  3. The dosage of other drugs can be from 10 mg to 40 mg. The amount depends on the characteristics of the inflammatory process and is selected by the doctor.

The question of whether it is possible to replace drugs in this group with histamine blockers can only be answered by the attending physician, who will take into account the indications and contraindications.


Typical treatment regimens

  1. Single drug therapy. This scheme is far from the most effective, since individual symptoms are not taken into account.
  2. Dynamic therapy. Drugs of different strengths are prescribed depending on the intensity of the inflammatory process. Treatment involves a strict diet and taking antacids. If there is no effect, stronger medications that are similar in their principle of action are prescribed.
  3. The third scheme involves taking strong proton pump blockers. When severe symptoms go away, weak prokinetic agents begin.

Traditional methods and homeopathy

These two concepts should not be confused. Homeopathy is a complex of therapeutic effects based on the fact that like can be cured by like. That is, when using medications that cause the same changes that are observed during the disease, there is a chance of being cured or significantly alleviating the condition and symptoms. The homeopathic approach is not supported by all doctors, as there is a danger of causing serious complications.

Traditional methods are based on the principles of traditional medicine, but they use plants and their parts. For example:

  • Celery root. Drink juice on an empty stomach, 1 tbsp. spoon 30 minutes before meals.
  • Collection of herbs: chamomile flowers (1 teaspoon), wormwood (2 teaspoons), mint (2 teaspoons). Pour this mixture into 1 liter of boiling water. Then let it sit for two hours. The healing infusion is filtered. Take 1/2 cup 30 minutes before meals.
  • Dill seeds. Take 2 teaspoons of seeds and grind them. Brew with one glass of boiling water. Let it brew for 2-3 hours, filter. Take 1 tbsp. spoon 4 times a day.

Mainly used are drugs that reduce acid formation in the stomach.

With reflux esophagitis, damage to the tissues of the lower esophagus occurs due to acidic contents refluxed from the stomach. This is precisely what explains the unpleasant sensations that bother a person - discomfort, sour belching, coughing. Similar symptoms inherent in reflux can be caused by many reasons. Therefore, only a specialist should prescribe the optimal treatment tactics - what medications, their doses, duration of use. Self-medication is unacceptable.

Conducted medical studies have convincingly shown that in order to cope with reflux esophagitis, treatment with drugs must be combined with other measures - diet therapy, correction of the patient’s lifestyle. Only by eliminating the true causes of the disease can you achieve your goal - to prevent relapses of the disease and eliminate unpleasant sensations.

Principles of treatment of reflux esophagitis:

  • reducing the acidity of the stomach contents to acceptable parameters by prescribing appropriate medications;
  • optimal stimulation of motility of the structures of the digestive tract - strengthening their evacuation activity;
  • restoration and protection of the mucous membrane of the esophageal tube with medications.

The causes and treatment of the disease are closely interrelated - by eliminating the former through the influence of the latter, the patient improves his own well-being. However, it is not recommended to independently purchase from a pharmacy and take this or that remedy for reflux disorder. Without knowing the mechanism of formation of the pathology and the point of application of the pharmacological action of the drug, you can achieve the opposite result - the appearance of severe complications.

Stages of treatment

The treatment regimen for reflux disease involves taking medications in 2 stages:

  1. healing of existing mucosal defects, relief of inflammatory processes;
  2. restoration of full activity of the esophageal tube and its natural sphincters.

The first stage requires taking drugs from anti-inflammatory and antiulcer subgroups for at least 6–8 weeks. The duration of pharmacotherapy directly depends on the severity of symptoms and the degree of tissue damage.

At the second stage, the patient takes maintenance doses of medications in order to prevent possible relapses and maximize the restoration of organ health. In severe cases, a person may require lifelong maintenance therapy.

To date, specialists have developed several drug treatment regimens for reflux esophagitis, which include drugs with different mechanisms of action and duration of onset of the desired effect.

Antacids and alginates

The purpose of using representatives of this subgroup of pharmaceuticals is to quickly neutralize hydrochloric acid in the stomach area. In addition, against the background of their use, a larger volume of bicarbonates is produced, natural protectors of the mucous membrane of the digestive structures. They also bind bile pigments and inactivate pepsin.

In most cases, specialists give preference to non-systemic medications that contain aluminum or magnesium. Modern antacids:

  • Almagel
  • Phosphalyuge
  • Maalox

It is optimal to take them in liquid form, which allows for high-quality distribution over the entire surface of the mucosa.

Antacids are designed specifically to reduce the acidity of gastric contents. The list of contraindications to them is minimal, for example, individual intolerance to active or auxiliary components.

Proton pump inhibitors

Special cells of the digestive tract are responsible for the production of hydrochloric acid. To reduce their hyperactivity, which is the main cause of the symptom of sour belching, it is necessary to take drugs from the subgroup of proton pump inhibitors.

Representatives of this subgroup, for example, Omez, Rabeprazole, Pantoprozole, have the following pharmacological effects:

  • a significant decrease in the level of basal as well as stimulated release of hydrochloric acid;
  • restoration of the physiological activity of cells in the mucous membrane of the stomach and esophageal tube.

Experts point out the undoubted advantages of these drugs, including Omeza:

  1. rapid onset of the desired effect;
  2. not absorbed into the systemic circulation;
  3. a minimum list of side effects on the patient’s body.

The structural features of the drug Omez allow it to be used for a long time at the second stage of pharmacotherapy. Symptoms of bitterness in the mouth and discomfort in the epigastric region, characteristic of gastric reflux, appear much less frequently due to this.

H2-histamine receptor blockers

Effective medications for esophagitis that have already proven themselves to be the best among both specialists and patients are H2-histamine receptor blockers. Prominent representatives of the subgroup are Ranitidine, Famotidine, Cimetidine, Roxatidine.

Their use serves the same purpose as proton pump blockers - to effectively reduce the concentration of acid in the digestive juice. They directly affect H2-histamine receptors, preventing their active activity, due to which the production of hydrochloric acid is significantly reduced.

The most effective representatives of this subgroup of medications are Famotidine and Roxatidine. When using them, there is less likelihood of withdrawal syndrome.

The undoubted advantages of the drugs include:

  • rapid decrease in the production of hydrochloric acid in the stomach;
  • a significant slowdown in pepsin secretion;
  • the possibility of using minimal doses to achieve a therapeutic effect;
  • stimulating the gastric mucosa’s own defenses;
  • improving local blood supply to tissues and accelerating their epithelization.

For esophagitis in adults, H2-histamine receptor blockers are used quite often. However, the optimal dose and duration of administration should be prescribed only by the attending physician.

Subgroup of prokinetics

Tablets for reflux, the main purpose of which is to enhance antropyloric motor function, are representatives of the prokinetic subgroup. Due to the acceleration of evacuation of the esophageal bolus from the stomach, reflux into the esophageal tube is weakened. There is also a pronounced stimulation of the tone of the lower cardia - a muscle ring that normally blocks the entrance to the stomach. The initiation of esophageal self-cleaning is also formed.

Help to cure reflux:

  1. Cerucal, Raglan - have the ability to enhance motility and tone of the gastrointestinal tract structures, as well as sphincters
  2. Motilium, Domperidone - the absence of systemic effects is indicated among the advantages
  3. Ganaton is the newest generation of prokinetics, helps accelerate the epithelization of erosions, and is effective even with severe inflammation.

How to take prokinetics, their doses and duration of pharmacotherapy should be determined only by a specialist. If the disease is mild, it is quite possible to completely cure it.

Subgroup of gastroprotectors

Effective drugs for the treatment of reflux, of course, are gastroprotectors. Thanks to timely use, they have a beneficial effect on the tissues of the esophageal tube, since they are able to increase the protective functions of digestive mucus.

Symptoms of the disease disappear much faster if complex pharmacotherapy includes:

  • Cytotec
  • Cytotech
  • Venter
  • Ursofalk
  • Sucralfate

Symptomatic therapy

Sometimes an exacerbation of the disease occurs due to nervous shock and psycho-emotional overload. In this case, it is not possible to cope with the problem only with the help of the above medications. To treat reflux, specialized help from a psychotherapist is required.

If the symptoms of bolus reflux are combined with spastic impulses, it is enough to take an antispasmodic, for example, Duspatalin. After eliminating the hyperspasm of the smooth muscles of the intestinal loops, relief occurs.

If a person prefers homeopathy, it should be taken into account that with its help it is possible to cope only with the initial stage of the disease. In case of severe reflux, multicomponent pharmacotherapy is necessarily prescribed.

Esophagitis is a disease that is associated with the development of an inflammatory process in the esophageal mucosa. This pathology leads to burning pain behind the sternum, heartburn and increased salivation, and difficulty swallowing. Therefore, treatment of esophagitis involves comprehensive and effective treatment. This will avoid the development of peptic ulcers and perforation, esophageal stenosis, and Barrett's disease.

Features of therapy

How to treat inflammation of the esophagus? The treatment regimen is determined by the course of the disease (acute or chronic form), the nature of the inflammatory process (catarrhal, erosive, edematous, exfoliative, hemorrhagic, phlegmonous esophagitis). It should be aimed at eliminating the causes that provoked the development of esophagitis: smoking, excess weight, unbalanced diet, stressful situations, elimination of chemical and bacterial agents.

It is possible to cure the disease completely only with an integrated approach: the use of medications, the use of traditional medicine recipes and the transition to a gentle diet.

Treatment of acute esophagitis

If damage to the esophageal mucosa develops due to exposure to chemicals, then the patient needs urgent gastric lavage. In case of a mild form of the pathology, the attending physician may recommend refraining from eating for 2-3 days, taking antacids (Phosphalugel, Almagel) and H2-histamine receptor blockers (Famotidine, Ranitidine). This will reduce the acidity of gastric juice, preventing further irritation of the esophageal mucosa.

In severe cases of esophagitis, enteral nutrition and the use of enveloping and antacid agents may be required. If the patient shows signs of intoxication (weakness, dizziness, confusion, headache, nausea, drowsiness), then infusion therapy with detoxification drugs is recommended. If the inflammation is caused by infectious agents, then the prescription of broad-spectrum antibiotics is indicated.

If a patient develops a severe stricture of the esophagus (narrowing of the organ to critical values), which cannot be dilated, then urgent surgical intervention is necessary.

Therapy for chronic esophagitis

This form of the disease usually develops against the background of gastroesophageal reflux disease (GERD). Treatment of chronic esophagitis involves changing the patient’s lifestyle, following a strict diet and a special diet. During an exacerbation, it is recommended to eat warm pureed food, excluding from the diet foods that can increase irritation of the esophageal mucosa (spicy, fried, fatty, carbonated drinks, alcohol).

The patient should stop smoking and use drugs that can reduce cardiac tone (sedatives, prostaglandins, tranquilizers, theophylline). Dinner should be 2 hours before bedtime; after a meal, you should not take a horizontal position. Gastroenterologists recommend raising the head of the bed by 40 0 ​​to prevent the development of reflux at night. You should avoid wearing clothes that fit around your waist.

Drug treatment involves the following:


To increase the effectiveness of drug treatment, patients with GERD are prescribed physiotherapeutic treatment (mud therapy, electrophoresis of ganglion blockers, amplipulse therapy, balneotherapy). However, during the period of exacerbation or in severe cases of the disease, it is worth abandoning the listed methods.

Features of therapy for some morphological forms:

  • Treatment of erosive esophagitis involves the prescription of antacids, prokinetics, and proton pump inhibitors. To relieve pain, you can use antispasmodics (Drotaverine, Papaverine, Spazmolgon). The patient must adhere to a dietary diet. If complications develop, then surgical intervention is indicated;
  • Therapy of acute hemorrhagic lesions of the esophagus requires the administration of hemostatic treatment. Otherwise, a standard treatment regimen is used: antacids, proton pump inhibitors, prokinetics;
  • treatment of candidal esophagitis involves the prescription of antifungal agents (Nystatin, Ketoconazole, Fluconazole), for heartburn, antacids and proton pump inhibitors are indicated, for sleep disturbances - B vitamins, sedatives. The patient must take immunostimulating drugs (IRS-19, Ekhingin, Imudon). Particular attention should be paid to nutrition - spices, pearl barley, sweets, mushrooms, alcohol, coffee should be excluded, because the fungus actively grows and multiplies when these products are consumed;
  • Therapy of phlegmonous esophagitis and abscess requires special attention. Patients require parenteral nutrition, and are also prescribed blood substitutes, antibiotics, and detoxification drugs. Pustules must be drained. If phlegmon develops, surgical intervention is indicated.

Use of traditional medicine

Treatment of esophagitis with folk remedies involves the use of the following recipes:


Therapy with folk remedies is possible if the patient has no contraindications to its implementation.

Diet therapy

In case of esophagitis, special attention must be paid to the foods taken, because there is no specific diet for the pathology. When preparing a diet, the patient should carefully monitor the body’s reaction to each dish.

However, there is a general list of prohibited products:

  • fresh wheat bread;
  • Rye bread;
  • fatty fish and meats;
  • salted, fried, smoked and spicy dishes;
  • conservation;
  • margarine and lard;
  • pearl barley, millet and barley porridge;
  • legumes;
  • fermented milk products;
  • soups using meat, fish and mushroom broths;
  • fresh fruits (except bananas);
  • vegetables: tomatoes, radishes, eggplants, raw onions and garlic, radishes;
  • coffee and chocolate;
  • ice cream;
  • carbonated and alcoholic drinks;
  • hot spices (mustard, chili, wasabi).

Esophagitis is a disease that can be completely cured if you follow a daily routine, nutrition and medication. In the absence of complications such as stenosis, perforation, bleeding, the pathology has a favorable prognosis.