Vilprafen analogues for genital infections. Side effects after using the medication. Prices for the drug and main analogues

"Vilprafen" is a broad-spectrum antibiotic from the macrolide group. It has a bacteriostatic effect, slowing down the reproduction and growth of bacteria. It has a bactericidal effect at high concentrations in the body of the source of inflammation. Active against gram-negative and gram-positive microorganisms. The maximum effect occurs within an hour after taking the drug. It is quickly absorbed from the gastrointestinal tract; bioavailability is not affected by the time of taking the drug. About 15-20% of the active substance josamycin binds to plasma protein and is quickly distributed throughout the organs and tissues of the body (except the brain). The therapeutic effect lasts for a long time at the active treatment level. The highest concentrations of the active substance are distributed in the tear fluid, tonsils, lungs, and sweat glands. It is excreted primarily in bile. The daily dose of Vilprafen for adults is usually 1-2 g in two or three doses. On the recommendation of a doctor, the dose may be increased. The average course of treatment is prescribed individually and can last from 5 to 21 days. Treatment is not prescribed in conjunction with other antibiotics, as they help reduce the antibacterial effect. During the lactation period and pregnancy, treatment is possible, but only under the supervision of the attending physician.

Indications for use

infectious diseases of the lower parts of the upper respiratory tract: chronic or acute bronchitis, pneumonia;
infectious diseases of ENT organs: paratonsillitis, tonsillitis;
infectious diseases of the upper respiratory tract: sinusitis, otitis, pharyngitis, laryngitis.
in the complex treatment of diphtheria;
infectious diseases of the genital and urinary tract: prostatitis, urethritis, epididymitis and so on;
whooping cough;
infections due to burns, wounds, accompanied by infectious foci of inflammation;
with hypersensitivity to penicillin in the treatment of scarlet fever;
chronic gastritis, duodenal and gastric ulcers caused by Helicobacter pylori bacteria;
psittacosis;
in case of hypersensitivity to penicillin, treatment of lymphogranuloma venereum, syphilis, gonorrhea;
infectious diseases of the oral cavity (in dental treatment);
infections of soft tissues, skin: abscesses, boils, erysipelas, felon, acne and so on:
with dacryocystitis, blephalit.

Possible adverse reactions

with individual tolerance to the constituent components, allergic reactions are possible in the form of itching, urticaria, bullous dermatitis, Steven-Johnson syndrome;
purpura is extremely rare;
discomfort in the gastrointestinal tract, constipation, nausea, colitis;
minor hearing impairment that resolves after discontinuation of the antibiotic;
symptoms of liver dysfunction.

Contraindications

intolerance to the constituent components of the antibiotic, in particular josamycin;
in severe forms of liver disease;
hypersensitivity to drugs belonging to the macrolide group;
children whose body weight is less than ten kilograms.

In case of renal failure, treatment is carried out on the basis of preliminary laboratory tests.

Analogues of "Vilprafen"

"Erythromycin"
A medicine from the group of macrolide antibiotics. Prescribed for treatment

erythrasmas;
diphtheria;
with trachoma;
legionnaires' diseases;
whooping cough;
syphilis, gonorrhea;
scarlet fever;
amoebic dysentery;
brucellosis;
bronchitis, pneumonia;
for conjunctivitis in infants;
infectious diseases of the urinary tract, including pregnant women;
infectious diseases of the respiratory tract and ENT organs;
with uncomplicated chlamydia;
for infections of mucous membranes, skin, soft tissues:
a prophylactic against streptococcal infections and infectious postoperative complications.

Not prescribed during the lactation period and during simultaneous treatment with other antibiotics.

"Clarithromycin"
Belongs to a group of synthetic antibiotics from the macrolide group.

Indications for use

Chronical bronchitis;
inflammatory and infectious diseases of the ENT organs and respiratory tract;
infections of soft tissues, skin, mucous membranes of the eyes;
prophylactic for immune deficiency syndrome;
otitis, sinusitis;
ulcer of the stomach, duodenum with confirmation of Helicobacter pylori bacteria:
other mycobacterial infections.

Treatment is contraindicated in the first trimester of pregnancy, in case of individual sensitivity to the constituent medicinal components, severe liver failure. Also analogues of “Vilprafen” are the following antibiotics; "Azithromycin"; "Roxithromycin"; "Spiramycin"; "Midecamycin"; "Roxolit"; "Midecamycin acetate"; ",Roxyhexal"; "Elrox" "Roxeptin" All drugs have approximately the same indications for treatment, contraindications, and possible side effects. Only the attending physician should decide to replace Vilprafen with any other analogue. Self-medication is dangerous to health, since the chronic and concomitant diseases of each individual patient are taken into account.

Vilprafen Solutab is the trade name of the macrolide antibiotic josamycin, which is used primarily for the treatment of bacterial pathologies of the ENT organs. Over time, it was also discovered that this drug has a much broader effect, which led to a significant expansion of indications for use.

Characteristics of Vilprafen

Vilprafen Solutab has a good bacteriostatic effect due to its ability to inhibit the functioning of the 50S ribosomal subunit of microbes. This leads to the inability of further reproduction of pathogenic bacteria, as well as a decrease in their resistance to the body’s immune response.

It acts on staphylococci, streptococci, neisseria, pneumococci, corynebacteria, mycoplasma, chlamydia, treponema and rickettsia.

The pharmacological properties of josamycin are special. The drug molecules are well absorbed when taken orally. Vilprafen Solutab is not used for intramuscular or intravenous administration. Antibiotic particles accumulate precisely in inflamed tissues, where their concentration can exceed the amount of the drug in the blood several times. Vilprafen is excreted from the body mainly by the kidneys in an unchanged state, which makes it possible to use it for infections of the genitourinary system.

Vilprafen Solutab is prescribed for the following conditions:

When using Vilprafen, side effects are rarely observed. Sometimes allergic reactions of varying severity occur (however, much less frequently than when prescribing beta-lactam antibiotics).

Cases of transient increases in the concentration of bilirubin and liver enzymes in peripheral blood, the development of toxic hepatitis, hearing loss, general fatigue and the appearance of edema of the lower extremities have been described.

The drug has a fairly small list of contraindications, which includes individual intolerance to the components of the drug, impaired renal function, pregnancy and lactation in women.

Also, neonatologists do not recommend prescribing Vilprafen during the newborn period of a child.

Vilprafen Solutab is prescribed to adults 500-1000 mg 2-3 times a day, depending on the severity of the pathology. For children, the antibiotic dosage must be individually calculated based on their age and body weight. Their usual daily dose is 50 mg/kg. The duration of treatment is from 5 to 14 days.

Vilprafen's analogs

Azithromycin, like Vilprafen analogue, is an antibacterial agent from the group of macrolide antibiotics. The drug is a representative of the azalide subclass, which introduces several features into the pharmacological characteristics of the antibiotic.

The drug has a bacteriostatic effect, like josamycin. The mechanism of action of these medications is also identical. However, the spectrum of sensitivity to azithromycin is somewhat narrower. This antibiotic has a more pronounced ability to accumulate in inflamed tissues of the body, in which its therapeutic concentration remains for up to 72 hours. This allows you to reduce the frequency of administration and course of antibiotic treatment.

As with other analogues of Vilprafen, the indications for prescribing azithromycin are almost identical. Azithromycin, as one of the safest and most effective antibiotics, is today included in treatment protocols for all antibacterial pathologies of the respiratory system and ENT organs.

It is given preference in cases of ineffectiveness of penicillins, or the presence of hypersensitivity to beta-lactam drugs (in addition to penicillins, this also includes cephalosporins, monobactams, carbapenems).

Azithromycin is also included in combination therapy for peptic ulcers to eradicate Helicobacter pylori infection.

Azithromycin should not be prescribed for the following conditions:

individual intolerance to the drug;
liver failure;
the presence of a congenital tendency to cardiac tachyarrhythmias.

During pregnancy, azithromycin is prescribed in cases where it cannot be replaced with a drug with a safer profile. In case of renal failure, it is necessary to carefully select the dosage of the drug based on glomerular filtration rates. It is advisable to monitor the concentration of the antibiotic in the blood plasma.

Azithromycin is prescribed to adults 500 mg once a day. Most pathologies require a 3-day course of therapy, but it can be continued if necessary. For children, a special form of antibiotic has been developed in the form of syrup, which also simplifies the dosage of the drug.

If we are talking about analogues of Vilprafen, then it is necessary to talk about Klacida. This drug also belongs to the group of macrolide antibiotics. Its active ingredient is clarithromycin. Like other representatives of this class of medications, Klacid has a bacteriostatic effect. But unlike josamycin, this drug does not have an effective effect on pathogens of urogenital infections.

However, Klacid inhibits almost the entire spectrum of mycoplasma and Helicobacter infections.

In the body, clarithromycin accumulates in affected tissues, but is eliminated much faster than azithromycin. At the same time, the drug shows the greatest effectiveness at neutral acidity. Therefore, to treat Helicobacter pylori infection, it must be combined with drugs that would reduce the production of gastric juice (proton pump inhibitors are most suitable).

In modern recommendations, clarithromycin is of greatest importance as a treatment for mycobacterial, legionella and Helicobacter pathologies. It is also used for bacterial infectious processes of the respiratory system and ENT organs.

Klacid is contraindicated for use if the patient has the following conditions:

allergies to macrolide drugs;
ventricular tachyarrhythmias or a high risk of their development;
hypokalemia;
liver failure;
simultaneous use of ticagrelor after myocardial infarction;
use of colchicine.

The most common side effects that occur when taking Klacid are:

transient increase in the concentration of bilirubin and liver enzymes in the blood plasma;
allergic reactions of varying severity;
the addition of a secondary bacterial, viral or fungal infection;
development of cardiac tachyarrhythmia;
inhibition of hematopoiesis (with clinical symptoms of anemia, internal or external hemorrhages, secondary infections);
toxic effect on the central nervous system (headache, dizziness, parasthesia);
functional disorders of the digestive system (nausea, vomiting, feeling of heaviness in the abdomen, loss of appetite, diarrhea).

It is not recommended to use the drug during lactation and pregnancy.

The course of treatment depends on the etiology of the bacterial process. For Helicobacter pylori infection, the course of treatment lasts at least 14 days, for most diseases of the respiratory system - 3-7, and for mycobacterial infection - from 10 days.

Amoxicillin is an antibacterial agent belonging to the group of synthetic penicillins. Unlike penicillin, this drug has a pronounced bactericidal effect. Its molecules are capable of disrupting the integrity of the cell membranes of pathogenic pathogens, which leads to their death and lysis.

The drug has an active effect on staphylococci, streptococci, pneumococci, corynebacteria, Haemophilus influenzae, clostridia, listeria, salmonella, shigella, Escherichia coli, Proteus, Klebsiella, Moraxella. This allows the antibiotic to be used for a wide range of bacterial infections of the respiratory and digestive systems.

When taken orally, the drug is partially absorbed. The therapeutic concentration of amoxicillin is maintained for 3-4 hours after administration. This determines the frequency of antibiotic use 3 times per day.

Amoxicillin is used for bacterial pathologies of the respiratory system (tracheitis, bronchitis, community-acquired pneumonia), ENT organs (otitis, sinusitis, pharyngitis, tonsillitis), intestinal infections (salmonellosis, shigellosis), cholecystitis, urethritis, cystitis and for the prevention of complications after surgical interventions. .

When prescribing amoxicillin, allergic reactions (rash with severe itching, dyspeptic disorders, Quincke's edema or anaphylactic shock) occur more often than with other analogues. Therefore, before prescribing, it is imperative to check with the patient whether he has previously had hypersensitivity reactions to beta-lactam antibiotics (penicillins, cephalosporins, monobactams and carbapenems).

In addition, the following side effects occur:

sleep disturbance;
headache and dizziness;
dyspeptic disorders;
toxic hepatitis and jaundice of the skin;
inhibition of hematopoiesis.

Despite the presence of these side effects, amoxicillin is considered a safer antibacterial drug than macrolides.

It is allowed to be used as a substitute for Vilprafen during pregnancy. However, it also has its drawback - many strains of bacteria have developed resistance to its action. What is best in each specific situation should be decided by a qualified doctor.

Amoxicillin is prescribed in the form of tablets for adults and syrup for children under 6 years of age.

Video

The video talks about how to quickly cure a cold, flu or acute respiratory viral infection. Opinion of an experienced doctor.

Characteristics of Vilprafen

It acts on staphylococci, streptococci, neisseria, pneumococci, corynebacteria, mycoplasma, chlamydia, treponema and rickettsia.

Vilprafen Solutab is prescribed for the following conditions:

When using Vilprafen, side effects are rarely observed. Sometimes allergic reactions of varying severity occur (however, much less frequently than when prescribing beta-lactam antibiotics).

Cases of transient increases in the concentration of bilirubin and liver enzymes in peripheral blood, the development of toxic hepatitis, hearing loss, general fatigue and the appearance of edema of the lower extremities have been described.

The drug has a fairly small list of contraindications, which includes individual intolerance to the components of the drug, impaired renal function, pregnancy and lactation in women.

Also, neonatologists do not recommend prescribing Vilprafen during the newborn period of a child.

Vilprafen's analogs

It is given preference in cases of ineffectiveness of penicillins, or the presence of hypersensitivity to beta-lactam drugs (in addition to penicillins, this also includes cephalosporins, monobactams, carbapenems).

Azithromycin is also included in combination therapy for peptic ulcers to eradicate Helicobacter pylori infection.

Azithromycin should not be prescribed for the following conditions:

individual intolerance to the drug;
liver failure;
the presence of a congenital tendency to cardiac tachyarrhythmias.

However, Klacid inhibits almost the entire spectrum of mycoplasma and Helicobacter infections.

Klacid is contraindicated for use if the patient has the following conditions:

allergies to macrolide drugs;
ventricular tachyarrhythmias or a high risk of their development;
hypokalemia;
liver failure;
simultaneous use of ticagrelor after myocardial infarction;
use of colchicine.

The most common side effects that occur when taking Klacid are:

transient increase in the concentration of bilirubin and liver enzymes in the blood plasma;
allergic reactions of varying severity;
the addition of a secondary bacterial, viral or fungal infection;
development of cardiac tachyarrhythmia;
inhibition of hematopoiesis (with clinical symptoms of anemia, internal or external hemorrhages, secondary infections);
toxic effect on the central nervous system (headache, dizziness, parasthesia);
functional disorders of the digestive system (nausea, vomiting, feeling of heaviness in the abdomen, loss of appetite, diarrhea).

It is not recommended to use the drug during lactation and pregnancy.

In addition, the following side effects occur:

sleep disturbance;
headache and dizziness;
dyspeptic disorders;
toxic hepatitis and jaundice of the skin;
inhibition of hematopoiesis.

Despite the presence of these side effects, amoxicillin is considered a safer antibacterial drug than macrolides.

Amoxicillin is prescribed in the form of tablets for adults and syrup for children under 6 years of age.

Video

The video talks about how to quickly cure a cold, flu or acute respiratory viral infection. Opinion of an experienced doctor.

What is the drug "Vilprafen 1000"? You will find the answer to this difficult medical question in the materials of this article. Also from it you will learn about how this medication should be taken, what it is intended for, whether it has side effects and contraindications, what can replace it, etc.

Composition, packaging and release form of the medical product

The drug "Vilprafen 1000" can be purchased at the pharmacy in the form of dispersible white tablets (they may also have a yellowish tint). They have an oblong shape with a score and the inscription “IOSA” on one side, with the number “1000” on the other. It should also be noted that this product has a sweetish taste and aroma of strawberries.

The active substance of the drug "Vilprafen 1000" is josamycin. As for the auxiliary components, these include aspartame, hyprolose, colloidal silicon dioxide, microcrystalline cellulose, sodium docusate, strawberry flavor and

The drug is sold in blisters of 5 tablets, placed in a cardboard box.

Pharmacological action of the drug

What is the drug "Vilprafen 1000"? The instructions for use of this medicine contain information that this drug is an antibiotic belonging to the macrolide group.

The mechanism of action of the medication in question is associated with a disruption of protein synthesis in microbial cells. This effect occurs due to the reversible binding of the active substance to the 50S ribosomal subunit.

In therapeutic volumes, this drug can have a bacteriostatic effect, slowing down the reproduction and growth of bacteria. If high concentrations are created at the site of inflammation, a bactericidal effect is possible.

The drug "Vilprafen 1000" shows particular activity against gram-positive and gram-negative microorganisms. However, it does not affect enterobacteria in any way. In this regard, this drug cannot negatively affect the state of the gastrointestinal microflora.

In some cases, the drug remains active in case of resistance to erythromycin, as well as other macrolides.

Pharmacokinetics of the drug

How long does it take for Vilprafen 1000 to be absorbed? The instructions for this product state that after ingestion, the active element of the drug is quite quickly absorbed from the digestive tract. However, food intake does not affect its bioavailability in any way.

The highest concentration of the drug is achieved approximately an hour after oral administration. At a dosage of 1 g, the maximum concentration is about 2-3 μg/ml.

The active substance of the drug is distributed quite well throughout the tissues and internal organs (with the exception of the brain). In this case, the medication creates concentrations that exceed plasma concentrations and remain at a therapeutic level for quite a long time.

High concentrations of josamycin are observed in the tonsils, lungs, saliva, tears and sweat. The medicine easily passes through and is also secreted in breast milk.

Josamycin (the active substance of the drug) is metabolized in the liver. In this case, active metabolites are formed.

The drug is excreted primarily in bile. But excretion with urine does not exceed 10%.

Indications for use of the medicine

In what cases should Vilprafen 1000 be used? We will look at reviews of this medication a little later. Now I would like to tell you that this medicine is prescribed only for infectious and inflammatory diseases that were caused by microorganisms sensitive to the drug:

Contraindications to the use of the medication

In what cases should Vilprafen Solutab 1000 not be used? Reviews from experts say that this medication has the following contraindications:

children with low body weight (less than 10 kg);
severe liver dysfunction;
hypersensitivity to the active substance;
hypersensitivity to antibiotic drugs belonging to the macrolide group.

Medicine "Vilprafen 1000": instructions for use of the drug

The dosage of this drug should be determined only by the attending physician and only on an individual basis.

For adults and adolescents over 14 years of age, the usual amount of this product is 1-2 g. It is recommended to take it in 2-3 doses. If necessary, the dose can be increased (for example, up to 3 g per day).

The daily dose for children whose body weight is at least 10 kg is prescribed based on the calculation of 40-50 mg per kg of weight. The medication must be taken 2-3 times a day.

A child weighing 20-40 kg is given 500-1000 mg twice a day (half or a whole tablet dissolved in water).

Children weighing more than 40 kg are prescribed 1000 mg (that is, one tablet) twice a day.

How long should I take Vilprafen (1000 mg)? The duration of treatment with this remedy is determined only by the doctor (usually it is 5-21 days, depending on the severity and nature of the infection).

Scheme of anti-Helicobacter therapy (treatment of stomach ulcers)

Now you know how to take Vilprafen Solutab 1000. If you need anti-Helicobacter therapy, then this medication is prescribed in a volume of 1 g twice a day for 1-2 weeks. In this case, the drug should be combined with other drugs in their standard doses (“Famotidine”, “Omeprazole”, “Omez”, “Omez D”, etc.).

The dispersible drug can be taken orally in a variety of ways. The tablets are swallowed whole (with water) or pre-dissolved in 20 ml of water. In the latter case, the resulting suspension must be thoroughly mixed before administration.

Side effects after using the medication

Analogues of "Vilprafen 1000", as well as the drug in question, can cause a number of undesirable reactions. The most commonly observed side effects are:

Digestive tract: stomach discomfort, abdominal discomfort, nausea, diarrhea, stomatitis, vomiting, constipation, pseudomembranous colitis and
Allergy: urticaria, exudative erythema multiforme, Quincke's edema, Stevens-Johnson syndrome).
Biliary tract and liver: jaundice, liver dysfunction.
Sense organs: dose-dependent transient hearing impairment.
Other: purpura.

Interaction with other medications

Since bacteriostatic antibiotics may reduce the antimicrobial effect of bactericidal antibiotics, their combined use should be avoided.

Representatives of the macrolide group noticeably slow down the elimination of xanthines. This may lead to symptoms of intoxication.

When josamycin is used concomitantly with astemizole or terfenadine, the risk of life-threatening arrhythmias may increase.

There are reports of increased vasoconstriction as a result of the combined use of macrolide antibiotics and ergot alkaloids.

Co-administration of cyclosporine and josamycin causes an increase in the level of cyclosporine in the blood and also increases the risk of nephrotoxicity.

When using digoxin and josamycin together, the level of the former in the blood may increase.

Special instructions for the use of the drug "Vilprafen 1000"

In case of severe and persistent diarrhea, it is necessary to keep in mind the possibility of developing life-threatening pseudomembranous colitis (while taking josamycin).

In patients with renal failure, therapy is recommended taking into account the results of laboratory tests.

It is necessary to take into account the possibility of cross-resistance to various antibiotics belonging to the macrolide group (bacteria resistant to treatment with antibiotics related in chemical structure may be resistant to josamycin).

Cost and analogues of the drug

The price of the drug in question is not very high. So, for 10 tablets of the drug you will have to pay about 150 Russian rubles. Agree, this is a fairly low cost, considering the effectiveness of the drug “Vilprafen 1000”. You are unlikely to find cheaper analogues in pharmacies.

If the medication in question is contraindicated for you, then it can be replaced with one of the following medications: Midekamycin, Roxithromycin, Spiramycin, Clarithromycin, Azithromycin or Erythromycin. These drugs are similar in active substance. This medication has no so-called structural analogues.

Vilprafen 500 is an antibiotic familiar to many people. However, the medicine is not suitable for some patients, and they want to choose high-quality analogues. However, before buying them, you need to find out in more detail what Vilprafen 1000 and other antibacterial medications are.

In this article we will look at the cheapest analogues of Vilprafen.

More information about the drug Vilprafen

Recently, society has been getting sick more and more often, which means we have to constantly deal with various medications. Vilprafen is considered one of the most popular of its kind. Its main element is a macrocyclic 16-membered lactone ring.

A high bacterial effect is achieved through a special process of inhibition of protein synthesis in all cells of the microorganism. When it comes to the development of high concentration inflammation, the medicine is bactericidal. To do this, it interacts with the 50S subunits of ribosomal membranes.

The main active substance in the drug is josamycin. Typically, the medication is prescribed to people suffering from the following diseases:

Thus, the medicine has a wide range of uses.

Instructions for use

The drug is prescribed in 1 g dose. three times a day. Duration of use depends on specific situations, The exact duration of therapy is prescribed by the doctor. The tablets should be taken during meals with plenty of water.

The drug is available in two forms: tablets and suspensions (for children).

It is important to note that the drug is highly acid-resistant. Due to this, there is almost no harm to the gastrointestinal tract. The main disadvantage of the drug is its cost.

The average price of a medicine ranges from 470 to 720 rubles. Therefore, many people try to find cheap analogues of Vilprafen.

Contraindications

Before purchasing, be sure to read the contraindications:

Doctors do not recommend using the pills for pregnant women. The only exceptions are those cases when this risk is justified. Therefore, if such situations arise, you need to choose gentle analogues for pregnant women.

Side effects of Vilprafen

In practice, there have been almost no cases where Vilprafen led to the development of side symptoms. It is usually well tolerated by patients. Dysbacteriosis, urticaria or stomach upset may occur. When taking a large amount, hearing loss may occur, which goes away after discontinuation.

List of cheap analogues of Vilprafen

(from 91 rub.);
Clarithromycin 500 (from 103 rub.);
Erythromycin 500 (from 112 rub.);
Roxithromycin 500 from 121 rubles;
Midecamycin 400 (Macropen) from 262 rub.
Flemoxin Solutab from 220 rub.
from 100 rub.
Klacid from 400 rub.

Vilprafen or Vilprafen Solutab - which is better?

Many people wonder which is better: Vilprafen or Vilprafen Solutab. To answer this, you should take a closer look at the differences.

Both drugs have a common active ingredient - josamycin and almost the same name. However, this does not mean that they are completely identical. There are two main differences:

Both medications are available in tablet form and are manufactured in Holland. The price of these tablets reaches 550-600 rubles, when regular Vilprafen costs about 500 rubles. Therefore, purchasing a product with a double dose of josamycin is almost 30% more profitable.

Vilprafen or Flemoxin - which is better?

Patients often compare these two drugs, wanting to find the highest quality and most effective. But to understand which product is in the lead, you need to carefully read Flemoxin.

Flemoxin Solutab is a drug based on a semi-synthetic antibiotic of the amoxicillin group of penicillins. It fights well against various microorganisms. There is a high-quality analogue of Flemoklav, which is capable of fighting bacteria that produce beta-lactose.

The drug is easily soluble in water and has high resistance to acidic environments. According to experts, it is considered one of the safest. The drug rarely provokes the development of side effects. Widely used to treat children, pregnant women and women during lactation.

Flemoxin is prescribed for the treatment of diseases of the following systems:

digestive;
urinary;
respiratory;
skin diseases.

When comparing two medications, you need to highlight the main differences:

Sharing

Both drugs are strong antibiotics, so your doctor rarely prescribes them at the same time. The reason for this is the fact that with a common union, the effectiveness of everyone decreases. Therefore, such experiments are not recommended.

It is difficult to say which drug should be preferred. Much depends on specific situations; the doctor must decide the choice independently, based on the diagnosis and tests of the patient.

Amoxiclav or Vilprafen – what to choose?

Amoxiclav is an antibiotic whose active ingredient is amoxicillin.

Indications for use:

Amoxiclav has a wide range of uses. Can be safely prescribed to pregnant women. However, before using it, you should carefully read the contraindications:

After a detailed study, two main differences can be identified:

Vilprafen temporarily stops the growth of the infection, but does not kill it. But its analog acts more efficiently, destroying the pest.
Price. Amoxiclav will cost several times less, its cost does not exceed 150 rubles.

Due to the occurrence of adverse reactions, the simultaneous use of drugs is prohibited. They can be combined, but only a day after consuming one of them. This can be done after consulting a doctor.

Vilprafen or Azithromycin

Azithromycin is effectively used to treat a number of complications and belongs to the group of macrolides. Available in three forms: powder, tablets and capsules. The main active ingredient is azithromycin dihydrate.

The drug is used to treat:

skin diseases;
respiratory tract;
peptic ulcer;
genitourinary system.

It is especially popular due to its effectiveness and safety. However, it has a number of side effects:

headache;
drowsiness;
development of anorexia;
insomnia;
sense of anxiety;
vision problems.

To avoid them, you must strictly adhere to the indicated dosage.

Contraindications:

kidney dysfunction;
children under 12 years of age;
people weighing up to 45 kilograms;
individual intolerance.

Pregnant women should use the drug with caution. The price of the drug does not exceed 150 rubles.

Vilprafen or Klacid - which is better?

Klacid is an antibiotic produced in the form of tablets and powder. Its active ingredient is clarithromycin. The medicine belongs to the group of macrolides. Qualitatively kills bacteria, even rare strains. Although there is an infection that he is not able to cope with - a gram-negative bacterium. In this case, it is necessary to use other tablets.

Indications for use:

development of infection in the respiratory tract;
conjunctivitis;
ENT diseases;
treatment of skin diseases;
ulcerative formations in the gastrointestinal tract.

The medicine can hardly be called cheap. Its cost can reach from 360 to 900 rubles.

Contraindications:

Before use, you should carefully read the instructions. Klacid does not combine well with many drugs. The tablets should be used with extreme caution by pregnant and lactating women.

Children under one year of age should also not be given this medicine. It is dangerous to prescribe such a strong antibiotic on your own; you should consult a pediatrician or therapist.

Side effects:

When comparing two antibiotics, you must take into account that each of them has its own active ingredient. So the drugs work in their own way. Many are sure that Klacid is less effective. In practice, this is confirmed, especially since the price of the medicine is clearly too high.

Each of the drugs presented has its own characteristics, advantages and disadvantages. Therefore, you can choose them only on the recommendation of a specialist.

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