Unienzyme tablets instructions for use. Unienzyme with MPS: what it is, instructions for use. Use for liver dysfunction
P N012401/01-191207Tradename: Unienzyme ® with MPS
Dosage form:
film-coated tabletsCompound:
Each film-coated tablet contains:
Active substances: fungal diastase (1:800) - 20 mg, papain (6000 U/mg) - 30 mg, simethicone - 50 mg, activated carbon - 75 mg, nicotinamide - 25 mg.
Excipients: microcrystalline cellulose, lactose, acacia gum, sodium benzoate, gelatin, colloidal silicon dioxide, talc, magnesium stearate, sodium carmellose.
Tablet shell: castor oil, shellac, calcium carbonate, charcoal, colloidal silicon dioxide, sucrose, acacia gum, gelatin, sodium benzoate, talc, carnauba wax, beeswax.
Inscription on the tablets: titanium dioxide
Description:
Black, oval-shaped, film-coated tablets with "UNICHEM" written in white on one side. Inhomogeneity of color is allowed.
Pharmacotherapeutic group:
digestive enzyme agentATX code: A09AA02
Pharmacological properties
Papain and fungal diastase are digestive enzymes that facilitate the digestion and absorption of proteins, fats and carbohydrates in the body. Simethicone has a carminative effect: it impedes the formation and promotes the destruction of gas bubbles, facilitates the removal of gases from the intestines, thereby reducing bloating, nausea, as well as pain and discomfort caused by flatulence.
Activated carbon is an adsorbent. Absorbs gases and toxins produced by indigestion. Nicotinamide (vitamin PP) has a regulating effect on digestive processes.
Indications for use
Pathological conditions accompanied by impaired exocrine function of the pancreas: chronic pancreatitis, pancreatectomy, condition after irradiation (as part of complex therapy). Flatulence, incl. in the postoperative period. Dyspepsia caused by unusual foods or overeating.
Contraindications
Hypersensitivity to the components of the drug, acute pancreatitis, exacerbation of chronic pancreatitis, children under 3 years of age.
Directions for use and doses
Inside. 1 tablet 1-2 times a day after meals.
Side effect
Allergic reactions, redness of the skin.
special instructions
During pregnancy and lactation, the drug should be used with caution under medical supervision.
Release form
10 tablets per aluminum foil strip.
2 strips along with instructions for use are placed in a cardboard box.
Or 2 strips along with instructions for use are placed in a cardboard box.
5 packs are placed in a cardboard box.
Storage conditions
At a temperature not exceeding 25 ° C in a dry place, protected from light.
Keep out of the reach of children.
Best before date
3 years. Do not use after the expiration date stated on the package.
Conditions for dispensing from pharmacies
Over the counter.
Manufacturer
Uniquem Laboratories Ltd.
Ind. Eria, Meerut Road, Ghaziabad 201 003, India
Representative office in the Russian Federation
119180, Moscow, st. B. Yakimanka, 31/18, office 408
In this article you can read the instructions for use of the drug Unienzyme with MPS. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Unienzyme in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Unienzyme analogues in the presence of existing structural analogues. Use for the treatment of pancreatitis, flatulence, dyspepsia in adults, children, as well as during pregnancy and lactation. Composition of the enzyme preparation.
Unienzyme with MPS- a digestive enzyme preparation with a component that reduces flatulence.
Papain and fungal diastase are digestive enzymes that facilitate the digestion and absorption of proteins, fats and carbohydrates in the body.
Simethicone complicates the formation and promotes the destruction of gas bubbles, facilitates the removal of gases from the intestines, thereby reducing bloating, nausea, pain and discomfort caused by flatulence.
Activated carbon adsorbs gases and toxins produced during digestive disorders.
Nicotinamide (vitamin PP) normalizes gastrointestinal motility.
Compound
Fungal diastase + Papain + Simethicone + Activated carbon + Nicotinamide + excipients.
Pharmacokinetics
The therapeutic effect of the drug is the combined effect of its components, so pharmacokinetic studies are not possible.
Indications
- as part of complex therapy of conditions accompanied by impaired exocrine function of the pancreas (chronic pancreatitis, liver disease);
- dyspepsia;
- flatulence (including in the postoperative period), a feeling of fullness in the stomach, nausea, belching caused by unusual food or overeating.
Release forms
Film-coated tablets.
Instructions for use and dosage regimen
The drug is prescribed orally, 1 tablet 1-2 times a day after meals. The tablets should be swallowed without chewing and washed down with plenty of water.
The duration of treatment is determined by the doctor depending on the nature of the disease.
Side effect
- allergic reactions;
- vomit;
- diarrhea;
- arrhythmia;
- hypotension;
- redness of the skin (especially the face and neck).
Contraindications
- acute pancreatitis;
- acute gastrointestinal diseases (stomach and duodenal ulcers);
- children under 7 years of age;
- hypersensitivity to the components of the drug.
Use during pregnancy and breastfeeding
The drug should be prescribed with caution during pregnancy and lactation (breastfeeding).
Use in children
Contraindicated in children under 7 years of age.
special instructions
The patient should be informed that if their health worsens or side effects occur, they should consult a doctor.
Drug interactions
There may be an increase in the need for insulin and oral antidiabetic drugs due to the presence of nicotinic acid in the drug.
Activated carbon can partially adsorb drugs, so the break between taking Unienzyme and taking other drugs should be at least 2 hours.
Analogues of the drug Unienzym
The drug Unienzyme with MPS has no structural analogues for the active substance. The drug contains a unique combination of active ingredients in its composition.
Analogs by pharmacological group (enzyme preparations and antienzymes):
- Abomin;
- Azopt;
- Aprotex;
- Aprotinin;
- Aerus;
- Brinzolamide;
- Gastenorm forte;
- Hemicellulase;
- Hyaluronidase;
- Gordoks;
- Diacarb;
- Digestal;
- Dorzopt;
- Iruksol;
- Karipazim;
- Contrikal;
- Kosopt;
- Creon;
- Lidaza;
- Longidaza;
- Mezim;
- Mezim forte;
- Let's take a look;
- Normoenzyme;
- Pangrol;
- Panzim forte;
- Panzinorm;
- Panzinorm forte;
- Pancreazim;
- Pancreatin;
- Pancreatin forte;
- Panolesis;
- Pancitrate;
- Papain;
- Penzital;
- Ribonuclease;
- Ronidaza;
- Sulbactam sodium;
- Trasylol;
- Trascolan;
- Trypsin;
- Trusopt;
- Ferestal;
- Festal;
- Festal N;
- Phlogenzyme;
- Chymopsin;
- Chymotrypsin;
- Tserezim;
- Elaprase;
- Enzistal;
- Enterosan;
- Hermital.
If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.
The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!
Unienzyme is a combined enzyme preparation containing a special component that reduces flatulence. The active components of Unienzyme are the main enzymes necessary for the complete and high-quality digestion of food. Thanks to this, Unienzyme compensates for the lack of activity or quantity of natural digestive enzymes produced by the human body and, thereby, improves the digestion of food with subsequent complete absorption of nutrients. Complete digestion of food under the influence of the enzymes of the drug Unienzyme also leads to the normalization of stool, eliminating the problem of constipation or diarrhea.By normalizing digestion, Unienzyme relieves the painful symptoms that develop when this process is disrupted. Thus, Unienzym effectively eliminates bloating, belching, a feeling of abdominal fullness, and also eliminates dyspepsia.
Release form and manufacturer
Unienzyme is available in a single dosage form - film-coated tablets. Full name of the drug – Unienzyme with MPS(UNIENZYME with MPS), where MPS is an abbreviation for a component that reduces flatulence. MPS stands for methylpolysiloxane - the chemical name of one of the components of the drug. However, the abbreviation “MPS” is often omitted from the name of the drug, and it is simply called Unienzyme. That is, Unienzym and Unienzym with MPS are two variants of the name of the same drug.Unienzyme is produced by the Indian pharmaceutical corporation UNICHEM Laboratories, Ltd., whose distributor in Russia is Transatlantic International CJSC. The tablets have a sugar coating, colored black. The shape of the tablets is oval. On one side, on a black field, there is a white inscription “Uniquem”. Tablets are available in packs of 20 or 100 pieces.
Compound
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- fungal diastase – 20 mg;
- papain – 30 mg;
- simethicone (methylpolysiloxane - MPS) - 50 mg;
- activated carbon – 75 mg;
- nicotinamide (vitamin PP) – 25 mg.
The auxiliary components of Unienzyme include the following substances:
- microcrystalline cellulose;
- acacia powder;
- calcium hydrogen phosphate;
- gelatin;
- talc;
- magnesium stearate;
- carmellose sodium;
- shellac;
- sucrose;
- titanium dioxide;
- Castor oil;
- calcium carbonate ;
- charcoal;
- sodium benzoate;
- wax;
- carnauba wax.
Action and therapeutic effects
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1. Proteolytic (efficient digestion of proteins).
2. Amylolytic (effective breakdown of starch and complex carbohydrates).
3. Lipolytic (effective digestion of fats).
4. Adsorbent (binds and removes toxic substances from the intestinal lumen).
5. Laxative (eliminates constipation and normalizes stool).
6. Reducing the process of gas formation.
All of these effects are due to the active components of the drug. Unienzyme tablets contain two digestive enzymes - fungal diastase and papain. Moreover, the maximum activity of these enzymes is observed at a pH of 5, and such acidity is observed immediately after eating. That is why the digestive enzymes papain and diastase begin to act in the stomach, and not just in the intestines, unlike other enzyme preparations.
Fungal diastasis is not a complete copy of the human one, produced by the pancreas. This diastase (amylase) is obtained from the fungi Aspergillus oryzae, which are grown on nutrient media. Unlike the pancreatic enzyme (human), fungal diastase contains two types of amylase. This gives diastase pronounced abilities to digest starch.
Fungal diastase is capable of breaking down starches in both the stomach and intestines. In addition, it is capable of breaking down and digesting a wide range of starch variants, unlike natural human pancreatic amylase. It is this effect of Unienzyme - excellent digestion of carbohydrate foods rich in starches (for example, potatoes and flour products) - that is called amylolytic.
Papain is a substance that is obtained from the fruit of the papaya plant. This enzyme helps digest protein structures, including those that are difficult to digest, such as milk casein. Moreover, papain works in an acidic and alkaline environment, therefore it acts both in the stomach and intestines. This is why this enzyme can be used in both hyperacid and hypoacid conditions. The enzymatic action of papain is similar to human pepsin. However, pepsin is not able to work in an alkaline environment, so the spectrum of action of papain is much wider.
Simethicone, or methylpolysiloxane (MPS), is an anti-foaming surfactant. By reducing the tension of gas bubbles in the intestine, they combine into relatively large bubbles, which are removed naturally or are sorbed by activated carbon contained in Unienzyme. Due to this action of simethicone in Unienzyme, bloating is eliminated and discomfort caused by flatulence is relieved.
Simethicone is not absorbed into the blood from the intestines - this substance is excreted unchanged from the body along with feces. In combination with digestive enzymes, simethicone relieves symptoms of increased gas formation, relieves bloating and belching. It is thanks to the combined action of simethicone and digestive enzymes that Unienzyme can be used for the treatment of various diseases that are accompanied by flatulence, belching, insufficiency of digestion or spasms of the large intestine.
Activated carbon in Unienzyme provides a sorbent effect, binding and removing various toxic substances from the intestinal lumen. Charcoal effectively absorbs not only toxins, but also gases, relieving the symptoms of flatulence. Activated carbon in combination with simethicone and digestive enzymes in Unienzyme significantly increases the overall effectiveness of the drug.
Nicotinamide (or vitamin PP) belongs to the B vitamins. Nicotinamide takes part in the digestion of carbohydrates, including starch. In addition, this substance is a necessary component for the normal functioning of intestinal microflora. Also, two very important substances are formed from Nicotinamide in the human body - nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), which take part in almost all biochemical reactions. NAD and NADP are special physiologically active forms of substances that act as coenzymes of many enzymes that catalyze biochemical transformations during metabolic processes.
Indications for use
Unienzyme tablets with MPS are used to eliminate digestive disorders and absorption of nutrients in the gastrointestinal tract. Indications for the use of Unienzyme are the following pathological conditions:- Dyspeptic symptoms provoked by unusual types of food or overeating (for example, belching of air, nausea, feeling of fullness in the stomach, abdominal discomfort, etc.).
- Dyspeptic symptoms due to various diseases.
- Gastritis with low acidity and low pepsin activity in gastric juice.
- Insufficiency of digestive enzymes produced by the pancreas, for example, in chronic pancreatitis, removed pancreas, liver pathology or condition after irradiation, etc.
- Flatulence of any origin, including after surgery.
- As a preparatory tool for obtaining a clear image during ultrasound, gastroscopy or radiography of the abdominal organs.
Unienzyme (tablets) – instructions for use
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Since Unienzym contains strictly dosed components, it is taken according to a certain schedule. There is no need to accurately calculate the individual dosage according to the activity of the enzymes included in the composition, or depending on the type of pathology. For any digestive disorders caused by diseases, or overeating and unusual food, adults and children over 7 years old take Unienzym 1 tablet 1 - 2 times a day.
The duration of treatment is determined by the severity of the condition. For example, in the complex treatment of various diseases of the digestive system, Unienzym is taken in courses of 2–3 weeks in order to normalize the process of food digestion. In general, if there is a deficiency of digestive enzymes, drugs from the Unienzyme group are taken for a long time - often for years. But to eliminate the consequences of banal overeating, it is enough to take Unienzym for several days so that the digestion process is completely normalized, and everything eaten is well absorbed.
As a prophylactic measure to prevent flatulence, Unienzym is taken immediately before the upcoming feast for one to two days. It is also enough to take the drug for 24 hours as a preparation for instrumental examinations of the abdominal organs (ultrasound, gastroscopy, radiography).
If you feel worse while using Unienzyme or if side effects occur, you should stop taking the pills and consult a doctor. The presence of activated carbon in the preparation can give the stool a black color.
Patients who have suffered from gastric or duodenal ulcers in the past and currently have diabetes mellitus, gout or liver failure should be careful when using the drug, carefully monitoring their health status.
Overdose
An overdose of Unienzyme tablets was never detected during the entire period of use of the drug.Interactions with other drugs
Interactions with other drugs were also not detected with Unienzyme.Use during pregnancy
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All of the listed digestive disorders, as well as their painful symptoms, are perfectly eliminated by Unienzyme. This medicine can be used during pregnancy, like any other enzyme preparation. However, in the situation of pregnant women, the duration of treatment should be minimized. For example, if after two days of using the pills the woman’s condition has returned to normal, then the drug should be discontinued. Thus, you can take the drug to eliminate the symptoms of dyspepsia periodically throughout pregnancy. The dosage of Unienzyme for pregnant women is exactly the same as for all adults - 1 tablet 1 - 2 times a day after meals.
Unienzym is especially good at relieving bloating in the early months of pregnancy, and also eliminates constipation and belching in the later stages. The instructions for use, which the manufacturer includes in each package of Unienzym, indicate that the drug should be used with caution in pregnant women. This phrase means that full clinical trials of the drug on pregnant women have not been conducted for obvious ethical reasons. And without the results of such studies, not a single manufacturer has the right to write that the drug is approved for use by pregnant women. However, when limited clinical trials involving healthy volunteers (in this case, pregnant women) did not reveal a negative effect of the drug on the condition of the fetus and the pregnant woman, this means that the instructions are allowed to write about the possibility of careful use of the drug.
Unienzyme for children (instructions for use)
For various digestive disorders in children over 7 years old, Unienzyme can be used. The drug perfectly eliminates bloating, belching, abdominal discomfort and stool disorders. Moreover, Unienzyme can be used in children both for the treatment of a functional state (for example, overeating) and for the treatment of serious diseases of the digestive tract (for example, pancreatitis or hepatitis).Most often, children experience unpleasant symptoms of digestive disorders after eating a large amount of not very healthy food at holidays, friends’ birthdays, etc. In addition, digestive disorders in children often occur when the child eats a heavy meal after several hours of abstaining from food (for example, on the road, etc.). Unienzyme will perfectly eliminate these functional digestive disorders and relieve the child of unpleasant symptoms such as bloating, belching, a feeling of fullness in the stomach, etc.
To eliminate the symptoms of digestive disorders, children over 7 years old take Unienzyme in the same way as adults - one tablet 1 - 2 times a day, immediately after meals.
Contraindications
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- Acute pancreatitis or exacerbation of chronic pancreatitis.
- Diseases of the gastrointestinal tract in the acute phase.
- Hypersensitivity, intolerance or allergic reaction to any component of the drug.
- Age under 7 years.
- Peptic ulcer of the stomach and duodenum in the past, or an exacerbation stage in the present.
- Diabetes.
- Gout.
- Liver failure.
Side effects
Since Unienzyme contains several components, the amounts of which are carefully balanced, it is generally well tolerated in most cases. The range of side effects of the drug is very narrow. Thus, the side effects of Unienzyme include allergic reactions, as well as redness of the skin, most often on the face or neck.High dosages of Unienzyme can cause severe redness of the skin, itching and abdominal pain, as well as exacerbation of stomach or duodenal ulcers. Also, when taking the drug in high doses, it is possible to develop nausea, vomiting, a feeling of severe heating of the extremities, dry skin, arrhythmia and headache as side effects.
Analogs
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Thus, analogues of Unienzyme include the following enzyme drugs:
Unienzyme (with MPS) – reviews
Almost all reviews about the drug Unienzyme are positive. On various forums and specialized platforms for reviews, there was not a single statement about the drug that was negative or contained a negative assessment. That is, all the people who left reviews after using the drug were satisfied with it. Some patients identified, from their point of view, any shortcomings, while another part of the people did not even find individual shortcomings in the drug. However, even the shortcomings that some people believe could not affect the overall positive assessment of Unienzyme.
So, according to most people who have used Unienzyme, it is a kind of 3 in 1 remedy, since it contains an adsorbent, digestive enzymes and an anti-bloating component. For this reason, many people consider it a universal drug that combines the advantages of three effective and necessary drugs - activated carbon, Festal or Mezim, and Espumisan (simethicone is the active ingredient of this drug against colic and flatulence). This is why people believe that one Unienzyme is enough to replace all three of the above drugs.
According to patient reviews, Unienzyme is an excellent, complex and well-balanced drug that can replace several medications needed to eliminate a “storm in the stomach.” However, some people note that in case of severe overeating, one tablet of Unienzyme is not enough to eliminate the digestive problem. In such a situation, patients increase the dosage and take 2 to 3 tablets. This increased dosage perfectly eliminates the consequences of excess in eating, especially if the food eaten was fatty, high-calorie and heavy.
Unienzyme (with MPS) – price
The drug Unienzyme is produced in India and imported to Russia. The cost of the drug depends on the price of the wholesale batch and the cost of taxes during customs clearance. That is why the price of the drug from different purchased batches may differ. When Unienzyme is imported into Russia, differences in its final cost in pharmacy chains are due to storage and transportation costs. The estimated cost of a package of 20 Unienzyme tablets in Russian pharmacy chains is 60 – 92 rubles.The last update of the description by the manufacturer was 03/15/2005
Filterable list
ATX
Pharmacological group
Nosological classification (ICD-10)
Composition and release form
10 pcs per strip; in a cardboard pack 10 or 2 strips; or in a cardboard pack 2 strips; There are 5 packs in a large cardboard box.
Description of the dosage form
Tablets are black, oval, sugar-coated, with the inscription “Uniquem” in white on one side.
pharmachologic effect
pharmachologic effect- carminative, enzymatic, improves digestion.Papain and fungal diastasis- digestive enzymes of non-animal origin that facilitate digestion and absorption of proteins, fats and carbohydrates in the body.
Simethicone has a carminative effect. It hinders the formation and promotes the destruction of gas bubbles, facilitates the removal of gases from the intestines, thereby reducing bloating, nausea, as well as pain and discomfort caused by flatulence.
Activated carbon is an adsorbent. Absorbs gases and toxins produced by indigestion.
Nicotinamide (vitamin PP) has a regulating effect on digestive processes.
Indications of the drug Unienzyme ® with MPS
Pathological conditions accompanied by impaired exocrine function of the pancreas: chronic pancreatitis, pancreatectomy, condition after irradiation (as part of complex therapy).
Flatulence, incl.
Dyspepsia caused by unusual foods or overeating.
Contraindications
Hypersensitivity to the components of the drug, acute pancreatitis, exacerbation of chronic pancreatitis.
Use during pregnancy and breastfeeding
During pregnancy and breastfeeding, it should be used with caution and under medical supervision.
Side effects
Allergic reactions, redness of the skin.
Directions for use and doses
Inside, after meals, 1 tablet. 1-2 times a day.
Storage conditions for the drug Unienzyme ® with MPS
In a dry place, protected from light, at a temperature not exceeding 25 °C.Keep out of the reach of children.
Shelf life of the drug Unienzyme ® with MPS
3 years.Do not use after the expiration date stated on the package.
Synonyms of nosological groups
ICD-10 rubric | Synonyms of diseases according to ICD-10 |
---|---|
K30 Dyspepsia | Fermentative dyspepsia |
Hyperacid dyspepsia | |
Putrid dyspepsia | |
Dyspepsia | |
Dyspepsia | |
Dyspepsia of nervous origin | |
Dyspepsia in pregnant women | |
Fermentative dyspepsia | |
Putrefactive dyspepsia | |
Drug-induced dyspepsia | |
Dyspepsia caused by diseases of the gastrointestinal tract | |
Dyspepsia caused by impaired gastrointestinal motility | |
Dyspeptic symptoms during pregnancy | |
Dyspeptic syndrome | |
Dyspeptic disorder | |
Gastric dyspepsia | |
Delayed gastric emptying | |
Slow digestion | |
Idiopathic dyspepsia | |
Acid dyspepsia | |
Upper gastrointestinal motility disorder | |
Indigestion | |
Nervous dyspepsia | |
Non-ulcer dyspepsia | |
Feeling of heaviness in the stomach after eating | |
Postprandial functional dyspepsia | |
Fermentation processes in the intestines | |
Stomach upsets | |
Gastrointestinal disorders | |
Digestive disorders | |
Gastrointestinal disorders | |
Stomach upset | |
Digestive disorder | |
Digestive disorders in infants | |
Symptoms of dyspepsia | |
Putrid dyspepsia syndrome | |
Putrefactive dyspepsia syndrome in young children | |
Digestive insufficiency syndrome | |
Non-ulcer dyspepsia syndrome | |
Toxic dyspepsia | |
Functional dyspepsia | |
Functional digestive disorders | |
Chronic dyspepsia | |
Chronic episodes of dyspepsia | |
Essential dyspepsia | |
K86.1 Other chronic pancreatitis | Exacerbation of chronic pancreatitis |
Recurrent pancreatitis | |
Pancreatitis with exocrine insufficiency | |
Chronic pancreatitis | |
Chronic pancreatitis | |
K86.9 Disease of the pancreas, unspecified | Pancreatic disease |
Insulitis | |
Pancreatic coma | |
Functional disorders of the pancreas | |
R14 Flatulence and related conditions | Bloating |
Bloating | |
Severe flatulence | |
Gases in the postoperative period | |
Degassing of the intestines before diagnostic studies | |
Degassing of the intestines before x-ray examination | |
Gas retention | |
Excessive formation and accumulation of gases in the gastrointestinal tract | |
Sour belching | |
Flatulence | |
Flatulence with increased gas formation in the gastrointestinal tract | |
Flatulence in infants | |
Flatulence in newborns | |
Flatulence caused by fatty or unusual foods | |
Flatulence caused by diseases of the gastrointestinal tract | |
Belching | |
Feeling bloated | |
Feeling of fullness in the stomach | |
Increased gas formation | |
Increased gas formation in the gastrointestinal tract | |
Increased formation and accumulation of gases in the gastrointestinal tract | |
Increased gas formation and accumulation of gases in the gastrointestinal tract | |
Feeling of fullness in the epigastrium | |
Feeling of fullness in the stomach | |
Feeling of heaviness in the stomach | |
Z51.0 Radiotherapy course | Adjunct to external beam radiotherapy |
Local X-ray irradiation | |
Radiation therapy | |
Cerebral edema associated with radiation therapy | |
Damage due to radiation therapy | |
Radiotherapy | |
Z72.4 Inappropriate diet and unhealthy eating habits | Dyspepsia caused by unusual foods or overeating |
Long-term diet therapy | |
Long-term or low-calorie diets | |
Gastrointestinal disorders caused by poor diet | |
Inadequate nutrition | |
Irregular eating | |
Unbalanced diets | |
Binge eating | |
Food poisoning | |
Errors in diet | |
Dieting | |
Following a strict diet | |
Special diets |
Unienzyme is a combined enzyme preparation that contains a special component to reduce flatulence. The complex of its active substances constitutes a set of the most necessary enzymes for proper digestion. Therefore, by replenishing the deficiency of those enzymes that the body produces to digest food or by enhancing their activity, the drug helps improve the digestive process with subsequent complete absorption of the nutrient.
Thus, providing digestion with the full effect of its enzymes, the drug Unienzyme normalizes stool and eliminates the problems of both constipation and diarrhea. Also, by putting the digestive process in order, the drug can relieve a person from bloating, belching and a feeling of heaviness in the stomach, as well as eliminate dyspepsia.
Release form and composition
The drug is produced exclusively in the form of coated tablets.
The active components in the composition of the drug are:
- Fungal diastase 20 milligrams – a necessary enzyme for digesting food;
- Papain 30 milligrams – a necessary enzyme for digesting food;
- Simethicone 50 milligrams – has a laxative effect;
- Activated carbon 75 milligrams - ensures binding of toxic substances;
- Nicotinamide 25 milligrams – regulates the digestive process, as well as normalizes it and significantly improves it.
Excipients in the composition of the drug are represented by the following substances:
- Microcrystalline cellulose;
- Lactose;
- Acacia powder;
- Calcium hydrogen phosphate;
- Gelatin;
- Talc;
- Magnesium stearate;
- Carmellose sodium;
- Shellac;
- Sucrose;
- Titanium dioxide;
- Castor oil;
- Calcium carbonate;
- Charcoal;
- Sodium benzoate;
- Wax;
- Carnauba wax.
Those who suffer from lactose intolerance should pay attention to the fact that the drug contains it in its composition.
Action of Unienzyme
Often, for various reasons, the digestive process in the human body is disrupted. The drug Unienzyme is a drug that can eliminate these disorders, since it has a number of pharmacological effects necessary for this.
Therapeutic effects of Unienzyme tablets:
- The proteolytic effect promotes efficient protein digestion;
- The amylolytic effect promotes the effective breakdown of starches and complex carbohydrates;
- The effect of lipolytic action contributes to the effective digestion of fats;
- The effect of the adsorbent action promotes the binding and removal of toxic substances from the intestinal lumen;
- The laxative effect helps eliminate constipation and normalize stool;
- The effect of reducing gas formation.
Each of these effects is due to the action of the active components included in the drug. In addition, the tablets contain digestive enzymes, the action of which begins directly in the stomach, unlike those drugs whose enzymes are activated only in the intestines. This is achieved due to the properties of these enzymes to exhibit maximum activity in such an acidic environment, which is observed immediately after eating.
Fungal diastasis , however, cannot be called completely identical to that produced by the pancreas. It is grown on a nutrient medium and contains more than one type of amylase, unlike the real enzyme. This gives it a pronounced ability to digest starches. In addition, it is capable of breaking them down both in the stomach and in the intestines, and it can digest a wide range of starchy varieties.
Papain– a substance of plant origin isolated from papaya fruits. Its task is to digest protein structures, and it copes with this quite successfully, working in both acidic and alkaline environments. Therefore, its effect extends to both the stomach and intestines. Its action as an enzyme is similar to pepsin, which is produced by the body. However, pepsin does not work in an alkaline environment, which means that papain has great potential.
Simethicone– This is a surfactant that eliminates foaming. It helps eliminate bloating in the abdomen and relieves the state of discomfort that provokes flatulence. The substance leaves the body without being absorbed into the blood and maintaining an unchanged appearance. Its elimination occurs in the feces. Combined with those digestive enzymes that are part of Unienzyme, simethicone helps eliminate the symptoms of excessive gas formation, which helps get rid of belching and abdominal bloating.
Activated carbon , which is part of the drug is able to ensure adsorption in the intestinal lumen, since it can bind and remove all toxins and gases present there, which significantly alleviates the symptomatic condition of flatulence.
Nicotinamide or vitamin PP, taking part in the breakdown of carbohydrates and starchy foods, is also one of the necessary components that helps normalize the functionality of the intestinal microflora. In addition, several important substances for the human body are formed from it, taking part in almost all biochemical processes in the body.
Unienzyme instructions
The drug Unienzyme can be purchased at any pharmacy without a doctor's prescription. In order to independently understand the recommendations for its use, it is a good idea to carefully study the instructions that accompany each package of the drug. It contains complete and reliable information on taking the drug and its indications, as well as all contraindications and side effects.
Unienzyme indications
The drug Unienzyme is used to eliminate disorders of the digestive process and improve the ability of the gastrointestinal tract to absorb nutrients from food taken. When the following pathological conditions occur in the body, indications for the use of the drug Unienzyme become in demand.
So, the drug is indicated for use:
- For dyspeptic symptoms caused by an unusual type of food or as a result of overeating in the form of belching air, nausea, a feeling of fullness in the abdomen, as well as discomfort in it;
- For dyspeptic symptoms, the background of which is various diseases;
- For gastritis with low acidity and low activity of pepsin, which is part of gastric juice;
- In case of insufficiency of any digestive enzyme produced by the pancreas, for example, if the patient suffers from chronic pancreatitis, or this organ has been removed, or liver pathology, as well as a condition after irradiation, etc.;
- For flatulence of any origin, including after surgery;
- As a preparatory tool for obtaining a clear image during ultrasound examination, as well as for gastroscopic or radiographic examination of the digestive organs.
Unienzyme contraindications
The use of the enzyme preparation Unienzyme is contraindicated if the following pathological or physical conditions occur:
- In case of acute pancreatitis or exacerbation of its chronic form;
- For diseases of the gastrointestinal tract during an exacerbation;
- In case of hypersensitivity, intolerance or allergic reaction to any component of the enzyme preparation.
- Children under seven years of age.
This list of contraindications to the use of the drug is called absolute. In addition to this list of contraindications, there are also relative contraindications, in which the tablets can still be taken with some caution and under close medical supervision.
Relative contraindications:
- With peptic ulcer of the stomach and duodenum in the past, or at the stage of exacerbation at the present time;
- For diabetes mellitus;
- For gout;
- For liver failure.
Unienzyme application
The drug Unienzyme should be taken orally immediately after meals. The tablet should be whole; it should be swallowed and washed down with half a glass of water. It is allowed to use natural fruit juice or milk instead of water when drinking the drug. Mineral water is also suitable for these purposes.
Due to the content of strictly dosed components in the drug, it must be taken using a certain scheme. However, there is no need to make calculations to calculate the individual dosage, since any digestive disorders, be it overeating, unusual food, or symptoms of a serious illness, require taking Unienzyme one tablet twice a day. This dosage regimen applies to both children from seven years of age and adults.
Determining the duration of taking the drug depends on the severity of the patient's condition. If it is necessary to carry out complex therapy for any disease of the digestive tract, Unienzyme can be taken as a course of treatment for about a month. And if you just need to eliminate the consequences of excessive food intake, the drug is taken only for a few days until the digestive process is completely normalized and everything eaten is absorbed.
If the patient experiences a constant lack of digestive enzymes, then the enzyme preparation Unienzyme can be taken for a long time.
The drug is also used for prophylactic purposes. For example, if a festive feast is expected, then it is advisable to take pills for two days before it. This measure will help prevent flatulence.
Also, before conducting various studies of internal organs, you need to take the drug the day before.
If you feel worse or have side effects while taking Unienzyme, you should immediately stop taking the tablets and consult a doctor.
We should not forget about the activated carbon included in the preparation, which can color stool in a dark color in order to protect yourself from unnecessary anxiety.
Those patients who suffer from diabetes, gout or liver failure should approach taking the drug with caution, trying to promptly monitor their health status. The same applies to those who have suffered a peptic ulcer in any part of the gastrointestinal tract.
Unienzyme during pregnancy
During pregnancy, a woman is often plagued by digestive disorders, for which there are more than enough reasons. These include changes in physiology and malfunctions in the functioning of organs such as the liver, pancreas, and stomach.
In addition, a pregnant woman reacts sensitively to every change in the diet, to the quality composition of products, as well as to ordinary overeating. Therefore, so often pregnant women suffer from bloating, flatulence, constipation, as well as belching and heartburn.
Unienzyme will cope perfectly with each of the listed digestive disorders, as well as the manifestation of their painful symptoms. During pregnancy, it is not prohibited to take it, like any other enzyme-acting drug. However, the duration of treatment with the drug should be minimized. As soon as the woman’s condition has improved, the drug must be discontinued immediately. The use of the drug periodically throughout pregnancy is allowed, since the woman should not experience suffering from indigestion.
The usual dosage regimen for the drug is 1 tablet twice a day immediately after meals.
Unienzyme for children
The drug Unienzyme can be used to treat children after they reach the age of seven, eliminating various disorders of the digestive process. It is advisable to take the drug when a small patient is bothered by bloating in the tummy, belching or discomfort in the abdominal cavity, as well as when the stool is disturbed.
The enzyme preparation can be prescribed as a treatment for functional disorders (overeating) and in the treatment of diseases of the gastrointestinal tract (pancreatitis, hepatitis).
In order to eliminate the symptoms of disorders in the digestive process, children over seven years of age, as well as adults, are prescribed one tablet twice a day immediately after meals.
Overdose of Unienzyme
There have never been any reports of overdose in all the years that the drug has been used.
Side effects
Having a balanced quantitative composition of several components, Unienzyme is well tolerated. The list of its side effects is very small. However, side effects of the drug can manifest themselves in the form of allergic reactions and redness of the skin, especially in the face and neck.
Drug interactions
No noteworthy information about drug interactions with the enzymatic drug Unienzyme when taken concomitantly with other drugs has been identified.
Unienzyme analogues
The drug Unienzyme has no synonyms among other enzyme preparations on the domestic pharmaceutical market. Only its analogues can be purchased in the pharmacy chain. This means that there is simply no other drug that can boast of having the enzymes that Unienzyme has. Analogues of the drug also contain enzymes as active ingredients, but they are different and have only a similar principle of action to the drug Unienzyme.
10,000 and Panzinorm forte 20,000 in tablet form;
Unienzyme price
The drug Unienzyme is of foreign origin, and is produced in India and then imported to Russia. Therefore, its cost depends on many factors, such as the price of the wholesale batch, taxes, and customs clearance. Thus, the price of a drug supplied to a pharmacy from different wholesale batches may differ. After the drug has already been imported into the country, the difference in price may arise from the costs of storing the drug, as well as its transportation should be taken into account here.
However, the drug is relatively inexpensive and has good affordability for buyers. The approximate price range for a package of Unienzim tablets, which contains 20 pieces, ranges from 60 to 90 rubles.