Comprehensive examination of the gastrointestinal tract. Gastrointestinal tract methods and features of direct examination of patients with diseases of the gastrointestinal tract Experimental and clinical methods for studying the gastrointestinal tract

State budgetary educational institution

higher professional education

"Omsk State Medical Academy"

Ministry of Health of the Russian Federation

Department of Propaedeutics of Internal Diseases

Laboratory and instrumental methods for diagnosing diseases of the gastrointestinal tract

S.S. Bunova, L.B. Rybkina, E.V. Usacheva

Study guide for students

UDC 616.34-07(075.8)
BBK 54.13-4ya73

This textbook presents laboratory and instrumental methods for diagnosing diseases of the gastrointestinal tract and outlines their diagnostic capabilities. The material is presented in a simple accessible form. The textbook contains 39 pictures, 3 tables, which will facilitate the assimilation of the material when working independently. The proposed textbook complements the textbook on propaedeutics of internal diseases. The presented test tasks are intended to consolidate the assimilation of the presented material.

This manual is intended for students studying in the following specialties: 060101 – General Medicine, 060103 – Pediatrics, 060105 – Medical and preventive medicine.

Preface
List of abbreviations

Chapter 2. Data from instrumental research methods for gastrointestinal diseases
1. Endoscopic research methods
1.1. Fibroesophagogastroduodenoscopy
1.2. Sigmoidoscopy
1.3. Colonoscopy
1.4. Enteroscopy
1.5. Capsule endoscopy
1.6. Chromoscopy (chromoendoscopy)
1.7. Diagnostic laparoscopy
2. X-ray research methods
2.1. Fluoroscopy (x-ray) of the esophagus and stomach
2.2. Computed tomography and multislice computed tomography of the abdominal organs
2.3. Survey radiography of the abdominal organs and study of the passage of barium through the intestines
2.4. Irrigoscopy
3. Ultrasound research methods
3.1. Ultrasound of the stomach
3.2. Ultrasound of the intestines (endorectal ultrasonography)
4. Functional diagnostic methods

4.2. Study of gastric secretion - aspiration-titration method (fractional study of gastric secretion using a thin probe)

Test tasks for self-study
Bibliography

Preface

Diseases of the gastrointestinal tract occupy one of the first places in the structure of morbidity, especially among young people of working age; the number of patients with pathologies of the digestive organs continues to increase. This is due to many factors: the prevalence of Helicobacter pylori infection in Russia, smoking, alcohol consumption, stress factors, the use of non-steroidal anti-inflammatory drugs, antibacterial and hormonal drugs, cytostatics, etc. Laboratory and instrumental research methods are an extremely important point in the diagnosis of gastrointestinal diseases tract, since they often occur latently, without obvious clinical signs. In addition, laboratory and instrumental methods for diseases of the esophagus, stomach and intestines are the main methods for monitoring the dynamics of the disease, monitoring the effectiveness of treatment and prognosis.

This textbook presents the diagnostic capabilities of laboratory and instrumental methods for diagnosing diseases of the esophagus, stomach and intestines, including general clinical and special laboratory research methods, endoscopic, radiological, ultrasound methods and methods of functional diagnostics.

Along with traditional studies that have become firmly established in practice, new modern methods for diagnosing diseases of the gastrointestinal tract were considered: quantitative determination of transferrin and hemoglobin in feces, determination of a marker of inflammation of the intestinal mucosa - fecal calprotectin, blood serum testing using the "GastroPanel", method diagnosing stomach cancer using a tumor marker in blood serum, modern methods for diagnosing Helicobacter pylori infection, capsule endoscopy, computed tomography and multislice computed tomography of the abdominal organs, ultrasound examination of the stomach and intestines (endorectal ultrasonography) and many others.

Currently, the potential of laboratory services has significantly increased as a result of the introduction of new laboratory technologies: polymerase chain reaction, immunochemical and enzyme immunoassays, which have taken a strong place on the diagnostic platform and allow screening, monitoring of certain pathologies and solving complex clinical problems.

Coprological research has not yet lost its importance in assessing the digestive capacity of the digestive system organs, for the selection of adequate enzyme replacement therapy. This method is easy to perform, does not require large material costs or special laboratory equipment, and is available in every medical institution. In addition, this manual describes in detail the main scatological syndromes.

For a better understanding of the diagnostic capabilities of laboratory and instrumental research methods and interpretation of the results obtained, the textbook presents 39 figures and 3 tables. The final part of the manual contains test tasks for self-preparation.

List of abbreviations

TANK - blood chemistry
BDS – major duodenal papilla
DPK - duodenum
ZhVP – bile ducts
ZhKB - cholelithiasis
Gastrointestinal tract – gastrointestinal tract
ELISA - linked immunosorbent assay
CT - CT scan
MSCT – multislice computed tomography
OAK - general blood analysis
OAM - general urine analysis
OBP – abdominal organs
p/z - line of sight
PCR – polymerase chain reaction
sozh – gastric mucosa
soe - erythrocyte sedimentation rate
Tf – transferrin in feces
Ultrasound - ultrasonography
FEGDS - fibroesophagogastroduodenoscopy
HP – Helicobacter pylori
Hb – hemoglobin in stool
NS1 – hydrochloric acid

Chapter 1. Data from laboratory research methods for diseases

1. Screening research methods

1.1. General blood analysis

1.2. General urine analysis

1.3. Blood chemistry

1.4. Examination of stool for worm eggs and protozoan cysts:

2. Special research methods

2.1. Stool research methods

2.1.1. Coprological research (coprogram)

Coprogram indicators Coprogram indicators are normal Changes in coprogram indicators in gastrointestinal diseases
Macroscopic examination
Amount of feces 100-200 g per day. When protein foods predominate in the diet, the amount of feces decreases, while vegetable feces increase. With a vegetarian diet, the amount of feces can reach 400-500 g. - Excretion of feces in a large volume (more than 300 g per day - polyfecal matter) is characteristic of diarrhea.
- A small volume of feces (less than 100 g per day) is characteristic of constipation.
Stool consistency Moderately dense (dense) - Thick consistency - with constant constipation due to excess water absorption
- Liquid or mushy consistency of stool - with increased peristalsis (due to insufficient absorption of water) or with abundant secretion of inflammatory exudate and mucus by the intestinal wall
- Ointment-like consistency - in the presence of a large amount of neutral fat (for example, in chronic pancreatitis with exocrine insufficiency)
- Foamy consistency - with enhanced fermentation processes in the colon and the formation of large amounts of carbon dioxide
Shape of feces
Cylindrical
- The form of stool in the form of “large lumps” - with a long stay of stool in the colon (hypomotor dysfunction of the colon in people with a sedentary lifestyle or who do not eat roughage, as well as in cases of colon cancer, diverticular disease)
- Shape in the form of small lumps - “sheep feces” indicates a spastic state of the intestines, during fasting, stomach and duodenal ulcers, a reflex nature after appendectomy, with hemorrhoids, anal fissure
- Ribbon or “pencil” shape - for diseases accompanied by stenosis or severe and prolonged spasm of the rectum, for rectal tumors
- Unformed feces - maldigestion and malabsorption syndrome. The Bristol Stool Form Scale (Fig. 1) is a medical classification of the forms of human feces, developed by Meyers Hayton at the University of Bristol, published in 1997.
Types 1 and 2 characterize constipation
Types 3 and 4 - normal stool
Type 5, 6 and 7 - diarrhea
SmellFecal (regular)- Long-term retention of feces in the colon (constipation) leads to the absorption of aromatic substances and the smell almost completely disappears
- During fermentation processes, the smell of feces is sour due to volatile fatty acids (butyric, acetic, valeric)
- Intensified putrefaction processes (putrefactive dyspepsia, decay of intestinal tumors) cause the appearance of a fetid odor as a result of the formation of hydrogen sulfide and methyl mercaptan
Color
Brown (when eating dairy foods - yellowish-brown, meat - dark brown). Ingestion of plant foods and some medications can change the color of stool (beets - reddish; blueberries, blackcurrants, blackberries, coffee, cocoa - dark brown; bismuth, iron color stool black)
- With obstruction of the biliary tract (stone, tumor, spasm or stenosis of the sphincter of Oddi) or with liver failure (acute hepatitis, cirrhosis of the liver), leading to a violation of the secretion of bilirubin, the flow of bile into the intestine stops or decreases, which leads to discoloration of stool, it becomes grayish-white, clayey (acholic feces)
- In case of exocrine pancreatic insufficiency - gray, since stercobilinogen is not oxidized to stercobilin
- Bleeding from the stomach, esophagus and small intestine is accompanied by the appearance of black stool - “tarry” (Melena)
- When bleeding from the distal parts of the colon and rectum (tumor, ulcers, hemorrhoids), depending on the degree of bleeding, the stool has a more or less pronounced red color
- In cholera, intestinal discharge is a gray inflammatory exudate with fibrin flakes and pieces of the colon mucosa (“rice water”)
- Dysentery is accompanied by the secretion of mucus, pus and scarlet blood
- Intestinal discharge with amoebiasis may have a jelly-like character, deep pink or red.
SlimeAbsent (or in scant quantity)- When the distal colon (especially the rectum) is affected, mucus occurs in the form of lumps, strands, ribbons or a glassy mass
- With enteritis, the mucus is soft, viscous, mixing with feces, giving it a jelly-like appearance
- Mucus covering the outside of formed stool in the form of thin lumps, occurs with constipation and inflammation of the large intestine
Blood
Absent
- When bleeding from the distal parts of the colon, the blood is located in the form of streaks, shreds and clots on formed stool
- Scarlet blood occurs when bleeding from the lower parts of the sigmoid and rectum (hemorrhoids, fissures, ulcers, tumors)
- Changed blood from the upper part of the digestive system (esophagus, stomach, duodenum), mixing with feces, colors it black (“tarry” feces, melena)
- Blood in the stool can be detected in infectious diseases (dysentery), ulcerative colitis, Crohn's disease, disintegrating colon tumors in the form of streaks, clots, up to profuse bleeding
Pus
Absent
- Pus on the surface of the stool is determined by severe inflammation and ulceration of the colon mucosa (ulcerative colitis, dysentery, disintegration of an intestinal tumor, intestinal tuberculosis), often together with blood and mucus
- Large amounts of pus without mucus are observed when opening paraintestinal abscesses
Leftover undigested food (lientorrhea)NoneSevere insufficiency of gastric and pancreatic digestion is accompanied by the release of undigested food residues

Chemical research

ReactionNeutral, less often slightly alkaline or slightly acidic- An acidic reaction (pH 5.0-6.5) is observed when iodophilic flora is activated, producing carbon dioxide and organic acids (fermentative dyspepsia)
- Alkaline reaction (pH 8.0-10.0) occurs with increased processes of protein putrefaction in the large intestine, activation of putrefactive flora that produces ammonia (putrefactive dyspepsia)
Reaction to blood (Gregersen reaction)NegativeA positive reaction to blood indicates bleeding in any part of the gastrointestinal tract (bleeding from the gums, rupture of varicose veins of the esophagus, erosive and ulcerative lesions of the gastrointestinal tract, tumors of any part of the gastrointestinal tract in the stage of decay)
Reaction to stercobilinPositive- The absence or sharp decrease in the amount of stercobilin in the feces (the reaction to stercobilin is negative) indicates obstruction of the common bile duct with a stone, compression by a tumor, stricture, stenosis of the common bile duct or a sharp decrease in liver function (for example, in acute viral hepatitis)
- An increase in the amount of stercobilin in feces occurs with massive hemolysis of red blood cells (hemolytic jaundice) or increased bile secretion
Reaction to bilirubinNegative, because the vital activity of the normal bacterial flora of the colon ensures the process of restoration of bilirubin into stercobilinogen, and then into stercobilinThe detection of unchanged bilirubin in the stool of an adult indicates a disruption in the process of bilirubin recovery in the intestine under the influence of microbial flora. Bilirubin can appear during rapid evacuation of food (sharp increase in intestinal motility), severe dysbiosis (syndrome of bacterial overgrowth in the colon) after taking antibacterial drugs
Vishnyakov-Triboulet reaction (for soluble protein)NegativeThe Vishnyakov-Triboulet reaction is used to identify a hidden inflammatory process. Detection of soluble protein in stool indicates inflammation of the intestinal mucosa (ulcerative colitis, Crohn's disease)

Microscopic examination

Muscle fibers:

With striations (unchanged, undigested)
- without striations (altered, overcooked)

None

Absent (or only a few in sight)

A large number of changed and unchanged muscle fibers in the feces ( Torheatorrhea) indicates a violation of proteolysis (digestion of proteins):
- in conditions accompanied by achlorhydria (lack of free HCl in gastric juice) and achylia (complete absence of secretion of HCl, pepsin and other components of gastric juice): atrophic pangastritis, condition after gastric resection
- with accelerated evacuation of food chyme from the intestines
- in case of violation of the exocrine function of the pancreas
- for putrefactive dyspepsia
Connective tissue (remnants of undigested vessels, ligaments, fascia, cartilage)
Absent
The presence of connective tissue in the stool indicates a deficiency of proteolytic enzymes of the stomach and is observed with hypo- and achlorhydria, achylia
Fat neutral
Fatty acid
Salts of fatty acids (soaps)
None
or meager
quantity
fatty salts
acids
Impaired digestion of fats and the appearance in the stool of large amounts of neutral fat, fatty acids and soaps is called Steatorrhea.
- with a decrease in lipase activity (exocrine pancreatic insufficiency, a mechanical obstruction to the outflow of pancreatic juice), steatorrhea is represented by neutral fat.
- if there is a violation of the flow of bile into the duodenum (a violation of the process of emulsification of fat in the small intestine) and if the absorption of fatty acids in the small intestine is impaired, fatty acids or salts of fatty acids (soaps) are found in the feces
Plant fiber (digestible) is found in the pulp of vegetables, fruits, legumes and grains. Indigestible fiber (the skin of fruits and vegetables, plant hairs, the epidermis of cereals) has no diagnostic value, since there are no enzymes in the human digestive system that break it down
Single cells in p/z
Occurs in large quantities during rapid evacuation of food from the stomach, achlorhydria, achylia, and with bacterial overgrowth syndrome in the colon (a marked decrease in normal microflora and an increase in pathogenic microflora in the colon)
Starch
Absent (or single starch cells)The presence of large amounts of starch in feces is called amilorrhea and is observed more often with increased intestinal motility, fermentative dyspepsia, less often with exocrine insufficiency of pancreatic digestion
Iodophilic microflora (clostridia)
Single in rare p/z (normally iodophilic flora lives in the ileocecal region of the colon)With a large amount of carbohydrates, clostridia multiply intensively. A large number of clostridia is regarded as fermentative dysbiosis
Epithelium
Absent or single cells of columnar epithelium in the p/zA large amount of columnar epithelium in the feces is observed in acute and chronic colitis of various etiologies
Leukocytes
Absent or single neutrophils in the p/z
A large number of leukocytes (usually neutrophils) are observed in acute and chronic enteritis and colitis of various etiologies, ulcerative necrotic lesions of the intestinal mucosa, intestinal tuberculosis, dysentery
Red blood cells
None
- the appearance of slightly changed red blood cells in the feces indicates the presence of bleeding from the colon, mainly from its distal parts (ulceration of the mucous membrane, disintegrating tumor of the rectum and sigmoid colon, anal fissures, hemorrhoids)
- during bleeding from the proximal colon, red blood cells are destroyed and are not detected by microscopy
- a large number of red blood cells in combination with leukocytes and cylindrical epithelium is characteristic of ulcerative necrotic lesions of the colon mucosa (ulcerative colitis, Crohn's disease with damage to the colon), polyposis and malignant neoplasms of the colon
Worm eggs
NoneEggs of roundworms, tapeworms, etc. indicate a corresponding helminthic infestation
Pathogenic protozoa
NoneCysts of dysenteric amoeba, lamblia, etc. indicate corresponding invasion by protozoa
Yeast cells
NoneFound in feces during treatment with antibiotics and corticosteroids. Identification of the fungus Candida albicans is carried out by culturing on special media (Sabouraud's medium, Microstix Candida) and indicates a fungal infection of the intestine
Calcium oxalate (oxalic lime crystals)AbsentThey enter the gastrointestinal system with plant foods and normally dissolve in the HCl of gastric juice to form calcium chloride. Detection of crystals is a sign of achlorhydria
Triple phosphate crystals
(ammonium phosphate magnesium)
NoneIt is formed in the large intestine during the breakdown of lecithin, nuclein and other products of protein decay. Triple phosphate crystals found in feces (pH 8.5-10.0) immediately after defecation indicate increased putrefaction in the colon

Scatological syndromes

Chewing deficiency syndrome

Mastication deficiency syndrome reveals insufficiency in the act of chewing food (detection of food particles in the stool, visible to the naked eye).

Causes of chewing deficiency syndrome:

  • missing molars
  • multiple dental caries with their destruction
The normal enzymatic activity of digestive secretions in the oral cavity is drowned out by waste products of pathogenic microflora. Appearance in the oral cavity abundant pathogenic flora reduces the enzymatic activity of the stomach and intestines, so insufficient chewing can stimulate the development of gastrogenic and enteral scatological syndromes.

Digestive insufficiency syndrome in the stomach (gastrogenic scatological syndrome)

Gastrogenic coprological syndrome develops as a result of impaired formation of hydrochloric acid and pepsinogen in the coolant.

Causes of gastrogenic scatological syndrome:

  • atrophic gastritis
  • stomach cancer
  • conditions after gastrectomy
  • erosions in the stomach
  • stomach ulcer
  • Zollinger-Ellison syndrome
Gastrogenic coprological syndrome is characterized by the detection in the feces of a large number of undigested muscle fibers (creatorrhoea), connective tissue in the form of elastic fibers, layers of digestible fiber and calcium oxalate crystals.

The presence of digestible fiber in feces is an indicator of a decrease in the amount of free HCl and impaired gastric digestion. During normal gastric digestion, digestible fiber is macerated (softened) by free HCl of gastric juice and becomes accessible to pancreatic and intestinal enzymes and is not found in feces.

Pancreatic digestive insufficiency syndrome (pancreatogenic scatological syndrome)

A true indicator of pancreatic digestive insufficiency is the appearance of neutral fat in the stool (steatorrhea), since lipases do not hydrolyze fats.

There are muscle fibers without striations (creatorrea), the presence of starch is possible, and polyfecal matter is characteristic; soft, ointment-like consistency; unformed feces; color gray; pungent, fetid odor, the reaction to stercobilin is positive.

Causes of pancreatogenic scatological syndrome:

  • chronic pancreatitis with exocrine insufficiency
  • pancreas cancer
  • conditions after pancreatectomy
  • cystic fibrosis with exocrine pancreatic insufficiency

Bile deficiency syndrome (hypo- or acholia) or hepatogenic scatological syndrome

Hepatogenic coprological syndrome develops due to the lack of bile ( acholia) or its insufficient supply ( hypocholia) in the KDP. As a result, bile acids that participate in the emulsification of fats and activate lipase do not enter the intestine, which is accompanied by impaired absorption of fatty acids in the small intestine. At the same time, intestinal motility, stimulated by bile, and its bactericidal effect are also reduced.

The surface of the stool becomes matte, granular due to the increased content of fat droplets, the consistency is ointment-like, grayish-white in color, the reaction to stercobilin is negative.

Microscopic examination reveals a large amount of fatty acids and their salts (soaps) - products of incomplete breakdown.

Causes of hepatogenic scatological syndrome:

  • diseases of the gallbladder (gallstones, obstruction of the common bile duct with a stone (choledocholithiasis), compression of the common bile duct and bile duct by a tumor of the head of the pancreas, severe strictures, stenosis of the common bile duct)
  • liver diseases (acute and chronic hepatitis, liver cirrhosis, liver cancer)

Syndrome of indigestion in the small intestine (enteral scatological syndrome)

Enteral coprological syndrome develops under the influence of two factors:

  • insufficiency of enzymatic activity of small intestinal secretions
  • decreased absorption of end products of hydrolysis of nutrients
Causes of enteral scatological syndrome:
  • mastication insufficiency syndrome gastric digestion insufficiency
  • insufficiency of separation or entry of bile into the duodenum
  • helminthic infestations of the small intestine and gallbladder
  • inflammatory diseases of the small intestine (enteritis of various etiologies), ulcerative lesions of the small intestine
  • endocrine diseases that cause increased intestinal motility (thyrotoxicosis)
  • diseases of the mesenteric glands (tuberculosis, lymphogranulomatosis, syphilis, lymphosarcoma)
  • Crohn's disease affecting the small intestine
  • disaccharidase deficiency, gluten enteropathy (celiac disease)
Scatological signs will vary depending on the cause of digestive disorders in the small intestine.

Colon indigestion syndrome

Causes of indigestion syndrome in the colon:

  • violation of the evacuation function of the colon - constipation, spastic dyskinesia of the colon
  • inflammatory bowel diseases (ulcerative colitis, Crohn's disease)
  • insufficiency of digestion in the large intestine, such as fermentative and putrefactive dyspepsia
  • massive intestinal damage by helminths, protozoa
With spastic dyskinesia of the colon and irritable bowel syndrome with constipation, the amount of feces is reduced, the consistency is dense, the feces are fragmented, in the form of small lumps, mucus envelops the feces in the form of ribbons and lumps, a moderate amount of cylindrical epithelium, single leukocytes.

A sign of colitis will be the appearance of mucus with leukocytes and columnar epithelium. With inflammation of the distal colon (ulcerative colitis), a decrease in the amount of feces is observed, the consistency is liquid, the feces are unformed, pathological impurities are present: mucus, pus, blood; sharply positive reaction to blood and Vishnyakov-Triboulet reaction; a large number of columnar epithelium, leukocytes and erythrocytes.

Insufficiency of digestion in the large intestine according to the type of fermentative and putrefactive dyspepsia:

  • Fermentative dyspepsia(dysbiosis, bacterial overgrowth syndrome in the colon) occurs due to impaired digestion of carbohydrates and is accompanied by an increase in the amount of iodophilic flora. Fermentation processes occur with an acidic pH environment (4.5-6.0). The stool is copious, liquid, foamy with a sour odor. Mucus mixed with feces. In addition, fermentative dyspepsia is characterized by the presence of large amounts of digestible fiber and starch in the feces.
  • Putrid dyspepsia more common in people suffering from gastritis with secretory insufficiency (due to the lack of free hydrochloric acid, food is not properly processed in the stomach). The digestion of proteins is disrupted, their decomposition occurs, and the resulting products irritate the intestinal mucosa and increase the secretion of fluid and mucus. Mucus is a good breeding ground for microbial flora. In putrefactive processes, feces have a liquid consistency, dark brown color, an alkaline reaction with a sharp, putrid odor and a large number of muscle fibers under microscopy.

2.1.2. Bacteriological examination of stool

Bacteriological examination of stool- sowing feces on nutrient media for the purpose of qualitative analysis and quantitative determination of normal intestinal microflora, as well as opportunistic and pathogenic forms of microorganisms.
Bacteriological culture of stool is used to diagnose intestinal bacterial overgrowth syndrome (intestinal dysbiosis), intestinal infections and monitor the effectiveness of their treatment:
  • quantitative assessment of microflora (bifido- and lactic acid bacteria, clostridia, opportunistic and pathogenic microflora, fungi) with determination of sensitivity to antibiotics and phages
  • identification of pathogens of intestinal infections (Shigella, Salmonella, Proteus, Pseudomonas, Yersinia enterocolitica, Campylobacter jejuni, E.coli, Candida, rotaviruses, adenoviruses)

2.1.3. Markers of damage to the intestinal mucosa:

A. examination of feces for occult blood (Gregersen reaction)
B. determination of transferrin (Tf) and hemoglobin (Hb) in feces

A. Examination of feces for occult blood (Gregersen reaction):

Hidden blood is blood that does not change the color of stool and is not detectable macroscopically or microscopically. The Gregersen reaction for detecting occult blood is based on the property of blood pigment to accelerate oxidative processes (chemical study).

A positive fecal occult blood reaction can occur when:

  • erosive and ulcerative lesions of the gastrointestinal tract
  • tumors of the stomach and intestines in the decay stage
  • infestations by helminths that injure the intestinal wall
  • rupture of varicose veins of the esophagus, cardia of the stomach, rectum (liver cirrhosis)
  • blood entering the digestive tract from the mouth and larynx
  • impurities in the stool of blood from hemorrhoids and anal fissures
The test allows you to determine hemoglobin in a minimum concentration of 0.05 mg/g of stool; positive result within 2-3 minutes.

B. Determination of transferrin (Tf) and hemoglobin (Hb) in feces(quantitative method (iFOB)) - identification of lesions of the intestinal mucosa. This test is much more sensitive than the fecal occult blood test. Transferrin persists for a longer time than hemoglobin in feces. An increase in transferrin levels indicates damage to the upper intestine, and hemoglobin indicates damage to the lower intestines. If both indicators are high, then this indicates the extent of the damage: the higher the indicator, the greater the depth or affected area.

These tests are of great importance in the diagnosis of colorectal cancer, as they can detect cancer both in the early stages (I and II) and in later stages (III and IV).

Indications for the determination of transferrin (Tf) and hemoglobin (Hb) in feces:

  • bowel cancer and suspicion of it
  • screening for colorectal cancer - as a preventive examination for people over 40 years of age (once a year)
  • monitoring the condition of the intestine after surgery (especially in the presence of a tumor process)
  • intestinal polyps and suspicion of their presence
  • chronic colitis, including ulcerative colitis
  • Crohn's disease and suspicion of it
  • examination of first- and second-degree family members who have been diagnosed with cancer or intestinal polyposis

2.1.4. Determination of a marker of inflammation of the intestinal mucosa - fecal calprotectin

Calprotectin is a calcium-binding protein secreted by neutrophils and monocytes. Calprotectin is a marker of leukocyte activity and inflammation in the intestine.

Indications for the determination of calprotectin in feces:

  • detection of acute inflammatory processes in the intestines
  • monitoring of inflammation activity during treatment for inflammatory bowel diseases (Crohn's disease, ulcerative colitis)
  • differential diagnosis of organic intestinal diseases from functionally caused ones (for example, irritable bowel syndrome)
2.1.5. Determination of Clostridium difficile antigen (toxin A and B) in stool- used to identify pseudomembranous colitis (against the background of long-term use of antibacterial drugs), in which the causative agent is this microorganism.

2.2. Blood serum examination using GastroPanel

"GastroPanel" is a set of specific laboratory tests that can detect the presence of coolant atrophy, assess the risk of developing stomach cancer and peptic ulcers, and determine HP infection. This panel includes:

  • gastrin-17 (G-17)
  • pepsinogen-I (PGI)
  • pepsinogen-II (PGII)
  • specific antibodies - immunoglobulins class G (IgG) to Helicobacter pylori
These indicators are determined using enzyme-linked immunosorbent assay (ELISA) technology.

Intragastric pH measurements are presented in Table 2.

Table 2. Intragastric pH-metry indicators
Gastric body pH hyperacid state normoacid
state
hypoacid
state
anacid
state
basal period <1,5 1,6-2,0 2,1-6,0 >6,0
after stimulation <1,2 1,2-2,0 2,1-3,0 3,1-5,0
(very weak reaction)
>5,1
pH of the antrum of the stomach alkalization compensation decreased alkalizing function subcompensation for alkalization decompensation of alkalization
basal period >5,0 - 2,0-4,9 <2,0
after stimulation >6,0 4,0-5,9 2,0-3,9 <2,0

4.2. Study of gastric secretion– aspiration-titration method (fractional study of gastric secretion using a thin probe).

The technique includes two stages:

  1. Study of basal secretion
  2. Stimulated secretion assay
Study of basal secretion: the day before the study, medications that inhibit gastric secretion are discontinued, and after a 12-14-hour fast in the morning, a thin gastric tube (Fig. 39) is inserted into the antrum of the stomach. The first portion, consisting of completely removed stomach contents, is placed in a test tube - this is the fasting portion. This portion is not taken into account when studying basal secretion. Then every 15 minutes the gastric juice is removed. The study is continued for an hour - thus, 4 portions are obtained, reflecting the level of basal secretion.

Study of stimulated secretion: parenteral stimulants of gastric secretion (histamine or pentagastrin - a synthetic analogue of gastrin) are currently used. So, after studying secretion in the basal phase, the patient is injected subcutaneously with histamine (0.01 mg/kg of the patient’s body weight - submaximal stimulation of the parietal cells of the coolant fluid or 0.04 mg/kg of the patient’s body weight - maximum stimulation of the parietal cells of the coolant fluid) or pentagastrin (6 mg /kg of patient's body weight). Gastric juice is then collected every 15 minutes. The resulting 4 servings within an hour constitute the volume of juice in the second phase of secretion - the phase of stimulated secretion.

Physical properties of gastric juice: normal gastric juice is almost colorless and odorless. Its yellowish or greenish color usually indicates an admixture of bile (duodenogastric reflux), and a reddish or brownish color indicates an admixture of blood (bleeding). The appearance of an unpleasant putrefactive odor indicates a significant disruption of gastric evacuation (pyloric stenosis) and the resulting putrefactive breakdown of proteins. Normal gastric juice contains only a small amount of mucus. An increase in mucus impurities indicates inflammation of the coolant, and the appearance of food residues in the resulting portions indicates serious disturbances in gastric evacuation (pyloric stenosis).

Normal gastric secretion indicators are presented in Table 3.

Table 3. Indicators of gastric secretion are normal
Indicators Normal values
Determination of clock voltage –
amount of gastric juice
produced by the stomach within an hour
Basal secretion phase: 50-100 ml per hour
- 100-150 ml per hour (submaximal histamine stimulation)
- 180-220 ml per hour (maximum histamine stimulation)
Determination of flow rate HCl free. – amount of HCl,
released into the lumen of the stomach per hour and expressed in milligram equivalents
Basal secretion phase: 1-4.5 mEq/l/hour
Stimulated secretion phase:
- 6.5-12 meq/l/hour (submaximal histamine stimulation)
- 16-24 meq/l/hour (maximum histamine stimulation)
Microscopic examination of gastric juice Leukocytes (neutrophils) single in the field of view
Single cylindrical epithelium in the field of view
Slime +

Interpretation of research results

1. Clock voltage change:

  • an increase in the amount of gastric juice indicates hypersecretion (erosive antral gastritis, ulcer of the antrum or duodenum, Zollinger-Ellison syndrome) or a violation of the evacuation of food from the stomach (pyloric stenosis)
  • a decrease in the amount of gastric juice indicates hyposecretion (atrophic pangastritis, stomach cancer) or accelerated evacuation of food from the stomach (motor diarrhea)
2. Change in flow-hour of free HCl:
  • normoacid state (normoaciditas)
  • hyperacidity (hyperaciditas) - ulcer of the antrum or duodenum, Zollinger-Ellison syndrome
  • hypoacid condition (hypoaciditas) - atrophic pangastritis, stomach cancer
  • anacid state (anaciditas), or complete absence of free HCl after maximum stimulation with pentagastrin or histamine.
3. Microscopic examination. Detection of leukocytes, columnar epithelium and mucus in large quantities during microscopy indicates inflammation of the coolant. With achlorhydria (lack of free hydrochloric acid in the phase of basal secretion), in addition to mucus, columnar epithelial cells can also be found.

Disadvantages of the aspiration-titration method that limit its use in practice:

  • removal of gastric juice disrupts the normal working conditions of the stomach; it is of little physiological value
  • Some of the stomach contents are inevitably removed through the pylorus
  • secretion and acidity indicators do not correspond to actual ones (as a rule, they are underestimated)
  • the secretory function of the stomach increases, since the probe itself is an irritant of the gastric glands
  • the aspiration method provokes the occurrence of duodenogastric reflux
  • it is impossible to determine night secretion and the circadian rhythm of secretion
  • it is impossible to assess acid formation after eating
In addition, there are a number of diseases and conditions for which the insertion of a probe is contraindicated:
  • varicose veins of the esophagus and stomach
  • burns, diverticula, strictures, stenosis of the esophagus
  • bleeding from the upper gastrointestinal tract (esophagus, stomach, duodenum)
  • aortic aneurysm
  • heart defects, cardiac arrhythmias, arterial hypertension, severe forms of coronary insufficiency

Test tasks for self-study


Select one or more correct answers.

1. Special laboratory tests for gastrointestinal diseases

  1. scatological research
  2. general blood analysis
  3. blood serum examination using GastroPanel
  4. bacteriological examination of stool
  5. general urine analysis
2. Changes in the general blood test, characteristic of inflammatory bowel diseases (ulcerative colitis, Crohn's disease)
  1. neutrophilic leukocytosis
  2. thrombocytosis
  3. anemia
  4. erythrocytosis
  5. acceleration of ESR
3. Anemia in a general blood test can be observed with:
  1. gastric ulcer complicated by bleeding
  2. condition after gastric resection
  3. chronic duodenitis
  4. cancer of the cecum in the decay stage
  5. opisthorchiasis
4. Changes in the biochemical blood test due to malabsorption in the small intestine:
  1. hypoproteinemia
  2. hyperproteinemia
  3. hyperlipidemia
  4. hypolipidemia
  5. hypokalemia
5. Normal coprogram is characterized by:
  1. positive reaction to stercobilin
  2. positive reaction to bilirubin
  3. positive Vishnyakov-Triboulet reaction (for soluble protein)
  4. microscopy shows a small amount of neutral fat
  5. microscopy shows a small amount of digested muscle fibers
6. Signs of bleeding from a duodenal ulcer:
  1. acholic feces
  2. "tarry" stool
  3. Gregersen's strongly positive reaction
  4. anemia
  5. polyfecal
7. In a coprogram, macroscopic indicators are
  1. muscle fibers
  2. stool color
  3. reaction to stercobilin
  4. stool consistency
  5. reaction to bilirubin
8. In a coprogram, the chemical indicators are
  1. reaction to stercobilin
  2. connective tissue
  3. shape of stool
  4. reaction to bilirubin
  5. Gregersen reaction
9. In a coprogram, macroscopic indicators are
  1. amount of stool
  2. neutral fat
  3. vegetable fiber (digestible)
  4. leukocytes
  5. red blood cells
10. Steatorrhea is a sign
  1. ahilia
  2. appendectomy
  3. hyperchlorhydria
  4. exocrine pancreatic insufficiency
  5. normal coprogram
11. Causes of hepatogenic scatological syndrome
  1. cholidocolithiasis
  2. stomach tumor
  3. tumor of the head of the pancreas
  4. cirrhosis of the liver
  5. atrophic gastritis
12. Markers of damage to the intestinal mucosa
  1. Gregersen reaction
  2. transferrin in feces
  3. reaction to bilirubin
  4. hemoglobin in stool
  5. reaction to stercobilin
13. Methods for diagnosing Helicobacter pylori infection
  1. morphological study of biopsy samples of the gastric mucosa
  2. X-ray
  3. urease breath test with 13C-urea
  4. rapid urease test
  5. bacteriological
14. Endoscopic methods for diagnosing gastrointestinal diseases are
  1. fibroesophagogastroduodenoscopy
  2. irrigoscopy
  3. colonoscopy
  4. fluoroscopy of the stomach
  5. sigmoidoscopy
15. X-ray methods for diagnosing gastrointestinal diseases are
  1. irrigoscopy
  2. sigmoidoscopy
  3. enteroscopy
  4. computed tomography of the abdominal organs
  5. fluoroscopy of the stomach
16. Options for intragastric pH-metry
  1. short-term
  2. aspiration
  3. endoscopic
  4. X-ray
  5. daily allowance
17. Indicators of gastric secretion determined by aspiration-titration method
  1. gastrin-17
  2. hourly voltage
  3. determination of IgG antibodies to Helicobacter pylori
  4. flow-hour of free HCl
  5. pepsinogen-I
18. A large amount of broken down and undigested fat in the stool is called _____________

19. A large number of changed and unchanged muscle fibers in feces is called___________

20 A large amount of starch in feces is called ____________

Answers to test tasks

1. 1, 3, 4 6. 2, 3, 4 11. 1, 3, 4 16. 1, 3, 5
2. 1, 3, 5 7. 2, 4 12. 1, 2, 4 17. 2, 4
3. 1, 2, 4 8. 1, 4, 5 13. 1, 3, 4, 5 18. steatorrhea
4. 1, 4, 5 9. 2, 3, 4, 5 14. 1, 3, 5 19. creatororrhea
5. 1, 5 10. 4 15. 1, 4, 5 20. amilorrhea

Bibliography
  1. Vasilenko V.Kh., Grebenev A.L., Golochevskaya V.S., Pletneva N.G., Sheptulin A.A. Propaedeutics of internal diseases / Ed. A.L. Grebeneva. Textbook. – 5th edition, revised and expanded. - M.: Medicine, 2001 – 592 p.
  2. Molostova V.V., Denisova I.A., Yurgel V.V. Scatological research in health and pathology: educational and methodological manual / Ed. Z.Sh. Golevtsova. – Omsk: Publishing House Omsk State Medical Academy, 2008. – 56 p.
  3. Molostova V.V., Golevtsova Z.Sh. Methods for studying the acid-forming function of the stomach: educational manual. Supplemented and revised. – Omsk: Publishing House Om-GMA, 2009. – 37 p.
  4. Aruin L.I., Kononov A.V., Mozgovoy S.I. International classification of chronic gastritis: what should be accepted and what is in doubt // Pathology Archives. – 2009. – Volume 71 – No. 4 – P. 11–18.
  5. Roytberg G.E., Strutynsky A.V. Internal illnesses. Laboratory and instrumental diagnostics: textbook. – Moscow: Publishing house MEDpress-inform, 2013. – 816 p.
  6. Electronic library of Omsk State Medical Academy. Access mode: weblib.omsk-osma.ru/.
  7. Electronic library system "KnigaFond". Access mode: htwww. knigafund.ru
  8. Electronic library system of the 1st Moscow State Medical University named after. I.M. Sechenov. Access mode: www. scsml.rssi.ru
  9. Scientific electronic library (eLibrary). Access mode: http://elibrary.ru
  10. Journal of Consilium Medicum. Access mode: www. consilium-medicum.com

To identify gastrointestinal pathologies in modern medicine, various research methods are used. The latest equipment helps to obtain valuable information about human health; in many cases, diagnosis does not cause discomfort. An anomaly can be detected even in situations where there are no complaints or external signs of illness.

Indications for examination of the gastrointestinal tract

Examination of the gastrointestinal tract is the most important step in making a correct diagnosis, since pathologies are common in people of all ages and can lead to serious consequences. Indications for intestinal examination are:

A stomach check is prescribed in the following cases:

  • internal bleeding;
  • gastritis (acute or chronic);
  • pancreatitis;
  • malignant formations;
  • gallstones;
  • stomach or duodenal ulcers;
  • pain of unknown etiology;
  • nausea, dry or bitter mouth;
  • belching and heartburn;
  • pronounced narrowing of the upper part of the stomach or its underdevelopment.

Often the entire gastrointestinal tract is examined. This allows you to determine the coherence of the organs or deviations in functioning.

Methods for diagnosing diseases of the gastrointestinal tract

Thanks to modern techniques, defect detection is now possible with minimal error. Standard tests are offered in any clinic, but many consider the procedures difficult to access, which is why they seek help when the pathology is at a late stage of development. Often one diagnostic method is sufficient; in complex cases they are combined. How to examine internal organs?

Physical approach

External non-invasive procedures are called physical techniques. These include palpation, percussion, visual inspection and auscultation. When examining a person, the doctor notes the following factors:

  • dullness and roughness of the skin;
  • pallor of the integument and deterioration of its elasticity;
  • smoothness of the tongue or the presence of a white/brown coating on it.

If a person does not have problems with the gastrointestinal tract, these symptoms are unusual for him. The examination allows you to make a preliminary diagnosis. If one of the signs is detected, the doctor performs superficial or deep palpation. The specialist presses on the stomach, moving upward from the groin area. In a healthy person, the muscles do not tense too much and there is no pain. Deep palpation is carried out in the area of ​​discomfort.


A rectal examination is necessary to examine the anus and determine its functionality. The procedure is performed by a proctologist, assessing the presence of fissures, hemorrhoids, and polyps.

Analyzes and laboratory tests

Diagnostics in the laboratory is a necessary measure for all diseases. To check the stomach and intestines, a specialist prescribes tests:

  • general blood test (performed in the morning, on an empty stomach);
  • examination of stool for the presence of protozoa;
  • examination of stool for worm eggs;
  • microflora analysis (for dysbacteriosis);
  • coprogram (comprehensive check of stool for changes in color, smell, shape, presence of various inclusions).

Instrumental methods

To examine the stomach and intestines, various instruments are often used that can show part of the organ or completely visualize parts of the gastrointestinal tract. How can you check your stomach and intestines? The following methods are relevant for the examination:

Radiation diagnostics

Patients may be offered non-invasive radiation examinations to help make a diagnosis. These include the following methods:

Possible complications after procedures

Most examinations are completely harmless, but some are quite unpleasant and painful, such as endoscopy and colonoscopy. For this reason, rectal tube insertion is performed under local anesthesia or sedation. The risk of complications is small, but it is there.

The consequences of different types of diagnostics are presented in the table.

Type of examinationComplications
ColonoscopyThe probability of problems occurring is 0.35%. Perforation, bleeding, infection, and reaction to the anesthetic are possible.
Swallowing the capsuleIn the presence of gastrointestinal hemorrhage, the device will provoke its intensification; electromagnetic radiation can damage the pacemaker.
EndoscopyA safe procedure, but possible allergies to the anesthetic, injury to the walls with perforation and bleeding, aspiration pneumonia, and infectious diseases.
LaparoscopyDamage to the vessels of the anterior abdominal wall.
Radioisotope surveyAllergy to “illuminating” drugs.
IrrigoscopyPerforation of the intestine and release of contrast into the peritoneal cavity (extremely rare).
CTDizziness and nausea during the procedure; in people with hypersensitivity, itching at the site of skin puncture when contrast is administered.

Or they are at risk, very often they ask the question: how to check the stomach and intestines? There are a large number of diagnostic methods that are highly effective and allow you to accurately determine the disease.

Doctors quite often prescribe a colonoscopy.

If a patient experiences pathological changes in the intestines or stomach, then he must undergo an instrumental examination. Doctors in most cases recommend:

  1. Magnetic resonance imaging;
  2. PET scan;
  3. Computed tomography;
  4. Capsule endoscopy;

Using these methods, it is possible to examine the gastrointestinal tract, as well as determine the presence of diseases. Some research methods require the use of anesthesia, since the person will not be able to tolerate the intervention. The choice of a particular research method directly depends on the characteristics of the development of the disease and the preliminary diagnosis.

Features of PET scanning and computed tomography

PET scanning as an effective diagnosis.

Computed tomography and PET scans are often used to examine the large and small intestines.

Using these research methods, the affected organs are visualized.

During the diagnosis, the doctor receives an image on an x-ray or computer monitor.

Equipment used for diagnostics visualizes the condition of internal organs using methods such as magnetic fields, ultraviolet waves, and X-rays.

Thanks to the use of computer imaging, it is possible to obtain several multilayer images of the stomach and intestines, which greatly simplifies the process of studying the condition of these organs for the doctor.

Using this research method, not only the internal, but also the external contour is assessed. Before the scan, the patient receives a contrast agent. The drug can also be administered intravenously during a computed tomography scan.

During the diagnostic period, images are taken in a special camera. That is why, if a patient has claustrophobia, testing is not recommended. Also, diagnosis is not carried out if the patient is excessively obese. Virtual colonoscopy is one of the types of computed tomography.

When using this method, it is possible to obtain images that have a three-dimensional image. This diagnosis is quite informative in the presence of growths on the intestinal walls, the size of which is more than one centimeter.

PET diagnostics involves the use of radioactive sugar, which produces images of the large and small intestines. It is infused into the patient intravenously before the study.

To carry out diagnostics, positron emission equipment is used, which is equipped with a special table for positioning the patient. The duration of the study is on average half an hour.

If the doctor has previously diagnosed the patient with early oncology, then this method is not used to confirm the diagnosis. But, with its help, the level of abnormalities in the inflamed intestinal wall, which was previously identified by a tomogram, is checked.

In case of intestinal cancer, using this research method, the presence of metastases in the lymphatic system and nearby organs is checked. Thanks to the possibility of simultaneous use of computed tomography and a PET scanner, the doctor can compare the images and make the diagnosis as accurately as possible.

To get a more complete picture, the doctor very often prescribes a test.

This video will tell you what capsule endoscopy is:

Carrying out ultrasound and MRI

Ultrasound is one of the diagnostic methods.

To check the intestines and stomach for the development of cancer, ultrasound is used.

It is used for fairly large tumors. If the patient has early or polyps in the gastrointestinal tract, then this method is not used for diagnosis.

In some cases, ultrasound is used to determine metastases of intestinal cancer in other organs.

If a patient is preliminarily diagnosed with rectal cancer, then endorectal ultrasound is used to confirm this diagnosis. For this purpose, a special device is used, which is inserted into the patient through the rectum.

Endorectal ultrasound makes it possible to determine the extent of pathological foci and the presence of pathological processes in the rectum and neighboring organs.
Magnetic resonance imaging can be used to diagnose diseases of the stomach and intestines.

When it is carried out, images are obtained on the computer screen that display sections of the patient’s body. This research method uses radio waves and strong magnets. During the examination, the human body absorbs the energy that the image displays. Thanks to the presence of a special program in the tomograph, the template is converted into an image.

Before the test, a person is given a drug that contains gadolinium. The distribution of the substance throughout the patient’s body occurs in different ways, depending on the location of the disease.

This makes it possible to distinguish between healthy and diseased tissues of the stomach and intestines. Compared to computed tomography, magnetic resonance imaging provides clearer images. If the patient has renal failure, this diagnostic method is not used. To determine this, capsule endoscopy is most often used.

This research method is based on the use of a capsule that has a built-in wireless camera of the smallest possible size. Thanks to this device, it is possible to obtain photographs of the stomach and intestines. The video tablet makes it possible to examine hard-to-reach areas. Unlike endoscopy, this method examines the small intestine.

Ultrasound, magnetic resonance imaging and capsule endoscopy are highly effective diagnostic methods that are characterized by a minimum number of contraindications.

Features of laparoscopy and endoscopy

Laparoscope is a tool for performing laparoscopy.

If the diagnostic case is unclear, then laparoscopy is used.

Using this research method, the depth of damage to the stomach is determined. This method can be used for not only diagnostics, but also surgical interventions. Using laparoscopy, gastric cancer is determined, as well as the extent of spread to neighboring organs.

During the examination, a special instrument is used - a laparoscope. Initially, the patient is given anesthesia. After this, an incision is made, the dimensions of which range from 0.5 to 1 centimeter.

Through it, a device is inserted, with the help of which carbon dioxide is pumped into the stomach. Thanks to this, the organ is enlarged, which allows you to get the most detailed picture. Next, a laparoscope is inserted into the resulting space.

Standard laparoscopy does not make it possible to determine the presence of metastases in. For this purpose, laparoscopic ultrasonography is used, which makes it possible to examine the abdominal organs. For this purpose, special laparoscopic sensors are used. With their help, hard-to-reach areas are explored.

Laparoscopy is practically the only diagnostic method that can be used to determine metastases before surgery. Endoscopy is performed using a special device - an endoscope.

It has a small camera that connects to a computer screen. Using this method, the upper parts of the digestive tract are examined. The endoscope tube must be swallowed by the patient during the examination.

Before this, the throat is irrigated using anesthetics. This makes the coping process easier. During the study, the walls of the stomach are examined using a camera. The doctor views the captured images with a camera in the endocope eye.

This research method allows you to take a biopsy. In some cases, using an endoscope, a catheter is inserted and all ducts are filled with radiopaque contrast. This makes it possible to take an X-ray of the gastrointestinal tract.

A variety of research methods can be used to determine the condition of the stomach and intestines. They should only be selected by a doctor in accordance with the indications and individual characteristics of the patient.


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Patient complaints:

1. Appetite disturbance (increase, decrease, absence - anorexia),

2. Perversion of taste (addiction to inedible substances, aversion to certain foods).

3. Belching (with air, odorless or odorless gas, food, sour, bitter).

4. Heartburn (frequency, intensity).

5. Nausea.

6. Vomiting (in the morning on an empty stomach, after eating, brings relief or without effect).

7. Pain in the abdominal area (localization, intensity, character, localization, connection with food intake, stool, gas, frequency, irradiation).

8. Flatulence.

9. Diarrhea (character, color, smell, presence of mucus, blood, pus).

10. Constipation (duration, shape, color of stool).

11. Skin itching.

12. Losing body weight.

History of the disease:

1. Onset of the disease, probable causes of its occurrence.

2. Development (frequency of exacerbations, variability of symptoms).

3. Treatment provided (frequency of hospitalizations, duration, effectiveness, medications used - constantly, periodically).

Life story:

1. Past diseases (presence of viral hepatitis, jaundice).

2. Nature of nutrition (irregular, dry food, monotonous, rough food, abuse of spicy seasonings).

3. Heredity (presence of peptic ulcer or cholelithiasis in blood relatives).

4. Bad habits.

5. Family and living conditions

6. Allergies (food, drug, household, presence of allergic diseases).

7. Long-term use of hormones, non-steroidal anti-inflammatory drugs, anti-tuberculosis drugs.

Physical examination:

1. Inspection: yellowness of the sclera, skin, scratch marks, decreased skin and tissue turgor, spider veins, swelling in the legs; changes in the tongue (plaque, atrophy of the papillae, dryness, discoloration), oral mucosa, teeth; examination of the abdomen (participation in the act of breathing, shape, size, symmetry of both halves, the presence of hernial protrusions, expansion of the venous network).

2. Palpation (tension, local pain (in the gall bladder, navel, sigmoid colon, epigastric region) or throughout the abdomen, liver - enlarged, painful, not palpable, spleen - palpable, not palpable, Kehr, Shchetkin-Blumberg symptoms) .

3. Percussion (Ortner's symptom).

Laboratory research methods:

1. Clinical analysis of blood and urine.

2. Biochemical blood test: protein and its fractions, prothrombin, fibrinogen, bilirubin, cholesterol, alkaline phosphatase, transaminases, amylase, lipase, trypsin inhibitor.

3. Urine analysis for diastase, bile pigments.

4. Fecal analysis (macro- and microscopic examination, bacteriological, for occult blood, for helminth eggs).


5. Serological blood tests.

6. Duodenal sounding.

7. Fractional study of gastric juice.

Instrumental research methods:

1. Stomach and duodenum: fluoroscopy, gastroduodenoscopy.

2. Intestines: irrigoscopy, sigmoidoscopy, colonoscopy.

3. Liver, biliary tract and pancreas6 Ultrasound, cholecystography, computed tomography, scanning, liver puncture biopsy, laparoscopy.

Stage II. Identifying patient problems.

In diseases of the digestive system, the most common problems of patients (real or real) are:

· loss of appetite;

· abdominal pain of various localization (specify);

· nausea;

· burping;

· heartburn;

· bloating;

· skin itching, etc.

In addition to the patient’s real, already existing problems, it is necessary to identify potential problems, that is, complications that may arise in the patient due to insufficient care and treatment, and unfavorable development of the disease. For diseases of the stomach and duodenum, these may be:

Ø transition of an acute disease to a chronic one;

Ø perforation of the ulcer;

Ø penetration of the ulcer;

Ø gastrointestinal bleeding;

Ø development of pyloric stenosis;

Ø development of stomach cancer, etc.

Possible problems with intestinal diseases:

Ø intestinal bleeding;

Ø development of intestinal cancer:

Ø dysbacteriosis;

Ø hypovitaminosis.

For diseases of the liver, biliary tract and pancreas:

Ø development of liver failure;

Ø development of liver cancer;

Ø development of diabetes mellitus;

Ø development of hepatic colic, etc.

In addition to physiological problems, the patient may have psychological ones, for example:

Lack of knowledge about your disease;

Feeling of false shame during special intestinal examinations;

Ignorance of the principles of therapeutic nutrition for your illness;

Lack of understanding of the need to give up bad habits;

Lack of understanding of the need for systematic treatment and visiting a doctor, etc. .

After identifying problems, the nurse determines nursing diagnosis, For example:

Increased gas formation (flatulence) due to intestinal digestion disorders;

Pain in the epigastric region after eating due to the formation of ulcers in the stomach;

Loss of appetite due to liver disease;

Heartburn due to chronic inflammation of the gastric mucosa;

Skin itching caused by liver failure;

Diarrhea due to inflammatory disease of the small intestine, etc.

Stage III. Planning nursing care and care.

The nurse sets priorities, forms short- and long-term goals, makes nursing choices (independent, interdependent and dependent), develops a plan of care and determines the expected outcome.

Independent nursing interventions for diseases of the digestive system may include:

Monitoring blood pressure, pulse, body weight, daily diuresis and stool;

Skin and mucous membrane care;

Timely change of bed and underwear;

Control over the transfer of food to the patient;

Creating a comfortable position in bed;

Training the patient and his family members to determine blood pressure, pulse rate, and provide first aid in emergency conditions;

Conversations about taking medications correctly, following a diet, and eliminating bad habits;

Feeding in bed;

Providing care items;

Providing emergency care for an attack of hepatic colic, gastric bleeding.

Interdependent nursing interventions:

Serving a heating pad and ice pack;

Preparing the patient and collecting biological material for laboratory tests;

Preparing the patient and accompanying him for instrumental types of examination;

Assist the doctor during abdominal puncture.

Dependent Nursing Interventions:

Timely and correct administration of medications prescribed by a doctor.

Stage IV. Implementation of the nursing intervention plan.

When implementing a nursing intervention plan, it is necessary to coordinate the actions of the nurse with the actions of other health care workers, the patient and his relatives, according to their plans and capabilities. The action coordinator is the nurse.

V stage. Evaluating the effectiveness of nursing interventions.

Efficiency assessment is carried out:

Ø by the patient (the patient’s reaction to nursing intervention);

Ø as a nurse (achieving the goal);

Ø by regulatory authorities (correctness of the nursing diagnosis, determination of goals and drawing up a plan for nursing interventions, compliance of the performed manipulations with the standards of nursing care).

Evaluating the effectiveness of the results allows you to:

§determine the quality of care;

§identify the patient’s response to nursing intervention;

§find new problems for the patient, identify the need for additional help.


Contrast studies of the gastrointestinal tract

The gastrointestinal tract (GIT) is often the object of contrast-enhanced X-ray examination. X-ray examination of the stomach, esophagus and small intestine is carried out on an empty stomach, the patient is prohibited from drinking and smoking on the day of the examination. In the case of severe flatulence (gas in the intestines), which interferes with the study in patients with colitis and constipation, more thorough preparation is necessary (see page 19).

The main contrast agent for examining the gastrointestinal tract is aqueous suspension of barium sulfate. Barium sulfate is used in two main forms. The first form is a powder mixed with water before use. The second form is a ready-to-use suspension for special x-ray studies. In clinical practice, two levels of barium concentration are used: one for conventional contrast, the second for double contrast.

For routine examination of the gastrointestinal tract, an aqueous suspension of barium sulfate is used. It has the consistency of semi-thick sour cream and can be stored in a glass container in a cool place for 3-4 days.

To conduct a double contrast study, it is necessary that the contrast agent has a high degree of dispersion and concentration of barium sulfate particles with a low suspension viscosity, as well as good adhesion to the gastrointestinal mucosa. To do this, various stabilizing additives are added to the barium suspension: gelatin, carboxymethylcellulose, flax seed mucilage, starch, marshmallow root extract, polyvinyl alcohol, etc. Ready-to-use, finely dispersed barium suspension of high concentration is produced in the form of finished preparations with various stabilizers, astringents, flavorings additives: barotrast, baroloid, barospers, micropack, mixobar, microtrust, novobarium, oratrast, skiabarium, sulfobar, telebrix, hexabrix, hitrast and others.

NB! Barium preparations are contraindicated in cases of suspected perforation of the gastrointestinal tract, since their entry into the abdominal cavity leads to severe peritonitis. In this case, water-soluble contrast agents are used.

A classic X-ray examination necessarily includes three stages:

Study of the relief of the mucous membrane;

Study of the shape and contours of organs;

Assessment of tone and peristalsis, elasticity of the walls.

Now contrasting only with barium suspension is gradually giving way to double contrasting with barium suspension and air. Double contrast is in most cases much more effective and is considered as a standard method for X-ray examination of the gastrointestinal tract. Inflating the examined part of the gastrointestinal tract with air helps to identify wall rigidity and uniform distribution of a small amount of barium suspension, which coats the mucous membrane with a thin layer. Contrasting only with barium is justified in elderly and debilitated patients, in the postoperative period and for special purposes - for example, when studying the motility of the gastrointestinal tract.

NB! With double contrast, as a rule, drugs are used to relax the muscles of the gastrointestinal tract (atropine, aeron; glucagon and buscopan, which paralyze motility). They are contraindicated for patients suffering from glaucoma and prostate adenoma with urination problems.

X-ray symptoms of various pathologies of the digestive tract can be grouped into ten main syndromes.

1. Narrowing of the lumen (deformation) of the esophagus, stomach or intestines occurs in a large group of pathological processes. This syndrome can be caused by both pathological processes emanating from the wall of the esophagus, stomach or intestines, and diseases of adjacent organs, as well as some developmental anomalies (malformations). Narrowing of the lumen often occurs after surgical interventions on the esophagus, stomach and intestines. The cause of narrowing of the lumen (spasm) of any part of the digestive canal can also be cortico-visceral and visceral-visceral disorders.

2. Expansion of the lumen(deformation) esophagus, stomach or intestines may be limited to a part of the organ (local) or involve the entire organ (diffuse) and reach varying degrees of severity. The expansion of the lumen of the organ is often combined with a significant accumulation of contents, usually gas and liquid.

3. Filling defect can occur in any part of the digestive tract and can be caused by various diseases of the organs or the presence of contents in their lumen.

4. Barium depot(niche) often occurs in pathological processes accompanied by organ destruction (ulcer, tumor, actinomycosis, syphilis, tuberculosis, erosive gastritis, ulcerative colitis), local bulging of the wall (diverticulum) or its deformation (related process, scar changes, consequences of injury or surgery interventions).

5. Changes in the relief of the mucous membrane- a syndrome, the timely detection of which contributes to the early recognition of many diseases of the esophagus, stomach and intestines. Changes in the relief of the mucous membrane can be manifested by thickening or thinning of folds, excessive tortuosity or straightening, immobility (rigidity), the appearance of additional growths on the folds, destruction (breakage), convergence (convergence) or divergence (divergence), as well as complete absence (“bare plateau") folds. The most informative image of the relief of the mucous membrane is obtained on images under double contrast conditions (barium and gas).

6. Impaired wall elasticity and peristalsis usually caused by inflammatory or tumor infiltration of the organ wall, a nearby process or other reasons. It is often combined with a decrease in the lumen of the organ in the affected area or its diffuse expansion (atony, paresis), the presence of pathological relief of the mucous membrane, a filling defect or barium depot (niche).

7. Violation of position- displacement (pushing, pulling, tugging) of the esophagus, stomach or intestines can occur as a result of damage to the organ itself (scarring ulcer, fibroplastic form of cancer, gastritis, colitis) or be a consequence of pathology in adjacent organs (heart defects, tumors and cysts of the mediastinum, abdominal cavity and retroperitoneal space, aneurysm of the thoracic or abdominal aorta). Violation of the position of the esophagus, stomach or intestines can be observed with certain anomalies and malformations, as well as after surgical interventions on the organs of the thoracic and abdominal cavities.

8. Accumulation of gas and fluid in the intestines accompanied by the formation of single or multiple horizontal levels with gas bubbles above them - Kloiber bowls. This syndrome is detected mainly when mechanical intestinal obstruction, developing as a result of narrowing of the intestinal lumen due to tumors, cicatricial changes in the intestinal wall, volvulus, intussusception and other reasons, as well as dynamic intestinal obstruction, which occurs reflexively during various pathological processes in the abdominal cavity and retroperitoneal space (appendicitis, pancreatitis, peritonitis).

9. Free gas and/or fluid (blood) in the abdominal cavity or retroperitoneum is detected in certain diseases (gastric or duodenal ulcer, ulcerative colitis, acute appendicitis) and injuries (closed abdominal trauma, penetrating wound, foreign body) accompanied by a violation of the integrity of the wall of a hollow organ. Free gas in the abdominal cavity can be detected after blowing out the fallopian tubes and surgical interventions (laparotomy).

10. Gas in the wall of a hollow organ can accumulate in the lymphatic crevices of the submucous and serous membranes of the stomach, small or large intestine in the form of small thin-walled cysts (pneumatosis cystoides), which are visible through the serous membrane.

Esophageal examination

The essence of the method: the method is simple, painless, but its information content and diagnostic value are several times inferior fibrogastroscopy- endoscopic examination of the esophagus and stomach. The most common indication for using the method is the patient’s fear and active reluctance to undergo fibrogastroscopy if there are certain complaints. Then an X-ray contrast study is performed, but if there is the slightest doubt or suspicion of pathology, endoscopy is performed.

Indications for the study: The main indication for the study is swallowing disorders (dysphagia), detection of hilar lymphadenopathy, tumors and mediastinal cysts. Besides:

Anomalies of the aortic arch and its branches,

Chest pain of unknown origin,

Foreign body in the pharynx and esophagus,

Mediastinal compression syndrome,

Bleeding from the upper alimentary canal,

Determination of the degree of heart enlargement, especially with mitral defects,

Suspicion of cardia failure or esophageal achalasia,

Suspected hiatal hernia.

Conducting research: The examination is carried out with the patient standing. The patient is asked to drink

barium suspension, and then stand next to the X-ray machine; the doctor adjusts the position of the device depending on the patient’s height. Next, the patient is asked not to move for a few minutes and told when the study is completed.

There are no contraindications to the study. There are no complications.

Preparing for the study: not required.

It must be carried out by a qualified radiologist, the final conclusion based on all data on the patient’s condition is made by the clinician who referred the patient for the study - a gastroenterologist, surgeon, oncologist, cardiologist.

Examination of the stomach and duodenum

The essence of the method: X-ray of the stomach allows you to clarify the position, size, contours, relief of the walls, mobility, functional state of the stomach, identify signs of various pathologies in the stomach and its localization (foreign bodies, ulcers, cancer, polyps, etc.).

Indications for the study:

Abdominal abscess;

Kidney amyloidosis;

Aspiration pneumonia;

Stomach ache;

Gastrinoma;

Gastritis is chronic;

Gastroesophageal reflux disease;

Hernia of the white line of the abdomen;

Hiatal hernia;

Dumping syndrome;

Benign stomach tumors;

Difficulty swallowing;

Foreign body of the stomach;

Ovarian cystoma;

Nephroptosis;

Liver tumors;

Acute gastritis;

Belching, nausea, vomiting;

Stomach polyps;

Portal hypertension;

Postoperative hernia;

Umbilical hernia;

Stomach cancer;

Ovarian cancer;

“Small signs” syndrome;

Zollinger-Ellison syndrome;

Decreased blood hemoglobin level (anemia);

Stomach ulcer.

Conducting research: the patient drinks a barium suspension, after which fluoroscopy, survey and targeted radiography are performed in different positions of the patient. The evacuation function of the stomach is assessed by dynamic radiography during the day. X-ray of the stomach with double contrast- a technique for contrast X-ray examination of the condition of the stomach against the background of its filling with barium and gas. To perform a double-contrast x-ray, the patient drinks a barium sulfate slurry through a tube with perforated walls, which allows air to enter the stomach. After massaging the anterior abdominal wall, barium is evenly distributed throughout the mucous membrane, and air straightens the folds of the stomach, allowing a more detailed examination of their relief.

Contraindications, consequences and complications: There are no absolute contraindications for X-rays of the stomach. Relative contraindications include pregnancy, ongoing gastric (esophageal) bleeding; as well as such changes in the lumbosacral spine that will not allow the patient to spend the necessary time lying on his back on a hard surface.

Preparing for the study: , i.e., exclude or limit dairy products, sweets, baked goods, carbonated water, cabbage, etc. The diet should contain lean meat, eggs, fish, and a small amount of water-based cereals. For constipation and flatulence, a cleansing enema is given in the morning on the day of the study, and if necessary, the stomach is washed.

Decoding the research results

Duodenal examination

The essence of the method: relaxation duodenography- contrast radiography of the duodenum in its relaxed state, artificially induced by drugs. The technique is informative for diagnosing various pathological changes in the intestine, head of the pancreas, and final sections of the bile duct.

Indications for the study:

Gastrinoma;

Duodenitis;

Small intestine cancer;

Zollinger-Ellison syndrome;

Bile duct strictures;

Duodenal ulcer.

Conducting research: In order to reduce intestinal tone, an injection of an anticholinergic agent is performed, then a portion of warm barium suspension and air is introduced through an intranasal probe installed into the lumen of the duodenum. Radiographs are performed under single and double contrast conditions in direct and oblique projections.

Preparing for the study: patients whose stomach and intestinal functions are not impaired do not require any special preparation. The only condition that must be met is not to eat 6–8 hours before the procedure. Patients suffering from any pathology of the stomach and intestines, and elderly people are recommended to begin to adhere to Diet to reduce gas, i.e., exclude or limit dairy products, sweets, baked goods, carbonated water, cabbage, etc. The diet may contain lean meat, eggs, fish, and a small amount of water-based cereals. For constipation and flatulence, a cleansing enema is given in the morning on the day of the study, and if necessary, the stomach is washed.

Decoding the research results should be carried out by a qualified radiologist, the final conclusion based on all data on the patient’s condition is made by the clinician who referred the patient for the study - a gastroenterologist, surgeon, oncologist.

Small intestine examination

The essence of the method: X-ray recording of the progress of contrast through the small intestine. By radiography of the passage of barium through the small intestine

Diverticula, strictures, obstructions, tumors, enteritis, ulcerations, disturbances of absorption and motility of the small intestine are detected.

Indications for the study:

Kidney amyloidosis;

Femoral hernia;

Crohn's disease;

Hernia of the white line of the abdomen;

Dumping syndrome;

Benign tumors of the small intestine;

Malabsorption;

Interintestinal abscess;

Inguinal hernia;

Postoperative hernia;

Umbilical hernia;

Small intestine cancer;

Celiac disease;

Enteritis;

Enterocolitis.

Conducting research: X-ray contrast examination of the small intestine is carried out after ingestion of a barium suspension solution. As the contrast moves through the small intestine, targeted radiographs are taken at intervals of 30–60 minutes. Radiography of the passage of barium through the small intestine is completed after contrasting all its sections and entering the barium into the cecum.

Preparing for the study: patients whose stomach and intestinal functions are not impaired do not require any special preparation. The only condition that must be met is not to eat 6-8 hours before the procedure. Patients suffering from any pathology of the stomach and intestines, and older people, already 2-3 days before the procedure, it is recommended to start following a diet that reduces gas formation, i.e. exclude or limit dairy products, sweets, baked goods, sparkling water, cabbage, etc. etc. The diet may include lean meat, eggs, fish, and a small amount of water-based cereals. For constipation and flatulence, a cleansing enema is given in the morning on the day of the study, and if necessary, the stomach is washed.

Decoding the research results should be carried out by a qualified radiologist, the final conclusion based on all data on the patient’s condition is made by the clinician who referred the patient for the study - a gastroenterologist, surgeon, oncologist.

Colon examination

X-ray examination of the large intestine is performed by two (or one might say three) methods: X-ray of the passage (passage) of barium through the large intestine And irrigoscopy(regular and double contrast).

X-ray of barium passage through the large intestine The essence of the method: a radiocontrast study technique performed to assess the evacuation function of the large intestine and the anatomical relationships of its parts with neighboring organs. X-ray of the passage of barium through the large intestine is indicated for prolonged constipation, chronic colitis, diaphragmatic hernia (to determine whether the colon is interested in them).

Indications for the study:

Appendicitis;

Hirschsprung's disease;

Crohn's disease;

Hernia of the white line of the abdomen;

Diarrhea (diarrhea);

Intestinal obstruction;

Megacolon;

Interintestinal abscess;

Nonspecific ulcerative colitis;

Perianal dermatitis;

Postoperative hernia;

Colon cancer;

Seronegative spondyloarthritis;

Irritable bowel syndrome;

Chronic appendicitis.

Conducting research: the day before the upcoming test, the patient drinks a glass of barium sulfate suspension; An x-ray examination of the large intestine is performed 24 hours after barium ingestion.

Preparing for the study: no special preparation is required.

Decoding the research results should be carried out by a qualified radiologist, the final conclusion based on all data on the patient’s condition is made by the clinician who referred the patient for the study - a gastroenterologist, surgeon, oncologist.

Irrigoscopy

The essence of the method: Unlike the passage of barium in the natural direction of movement of masses in the intestine, irrigoscopy is performed by filling the large intestine with a contrast agent using an enema - in a retrograde direction. Irrigoscopy is performed to diagnose developmental anomalies, cicatricial narrowings, tumors of the large intestine, chronic colitis, fistulas, etc. After tightly filling the large intestine with a barium suspension, the shape, location, length, distensibility, and elasticity of the intestine are studied using an enema. After bowel movement from the contrast suspension, organic and functional changes in the wall of the colon are examined.

Modern medicine uses irrigoscopy with simple contrast of the colon(using barium sulfate solution) and irrigoscopy with double contrast(using a suspension of barium and air). Tight single contrast allows you to obtain an x-ray image of the contours of the colon; irrigoscopy with double contrast reveals intraluminal tumors, ulcerative defects, inflammatory changes in the mucosa.

Indications for the study:

Abdominal abscess;

Anal itching;

Anococcygeus pain syndrome ( coccydynia);

Appendicitis;

Femoral hernia;

Hirschsprung's disease;

Rectal prolapse;

Haemorrhoids;

Hernia of the white line of the abdomen;

Diarrhea (diarrhea);

Benign tumors of the small intestine;

Benign ovarian tumors;

Gastrointestinal bleeding;

Ovarian cystoma;

Intestinal obstruction;

Megacolon;

Interintestinal abscess;

Lightning acne;

Nephroptosis;

Liver tumors;

Inguinal hernia;

Perianal dermatitis;

Rectal polyps;

Postoperative hernia;

Pseudomucinous ovarian cystoma;

Anal cancer;

Liver cancer;

Cancer of the uterus;

Colon cancer;

Small intestine cancer;

Cervical cancer;

Ovarian cancer;

Birth injury;

Uterine sarcoma;

Vaginal fistulas;

Rectal fistulas;

Seronegative spondyloarthritis;

Irritable bowel syndrome (IBS);

Chronic appendicitis.

Conducting research: The patient is placed on an inclined table and a plain radiography of the abdominal cavity is performed. Then the intestines are filled with a barium solution (an aqueous suspension of barium sulfate heated to 33–35 °C). In this case, the patient is warned about the possibility of a feeling of fullness, pressure, spastic pain or the urge to defecate and is asked to breathe slowly and deeply through the mouth. To better fill the intestine, during irrigoscopy the tilt of the table and the position of the patient are changed, and pressure on the abdomen is made.

As the intestine straightens, targeted radiographs are taken; after complete tight filling of the lumen of the colon - a survey radiography of the abdominal cavity. The patient is then escorted to the toilet to have a bowel movement naturally. After removal of the barium suspension, a survey X-ray is again performed to assess the relief of the mucosa and the evacuation function of the colon.

Double-contrast barium enema can be performed immediately after simple barium enema. In this case, the intestine is dosed with air.

Contraindications, consequences and complications: irrigoscopy is not performed during pregnancy, general severe somatic status, tachycardia, rapidly developing ulcerative colitis, or suspected perforation of the intestinal wall. Extra Caution when performing irrigoscopy it is required in case of intestinal obstruction, diverticulitis, ulcerative colitis, loose stool mixed with blood, cystic pneumatosis intestinalis.

NB! factors that can distort the results of irrigoscopy may be:

Poor bowel preparation

The presence of barium residues in the intestines after previous studies (radiography of the small intestine, stomach, esophagus),

The patient's inability to retain barium in the intestines.

Preparing for the study: Before irrigoscopy, a thorough bowel preparation is carried out, including a slag-free diet, cleansing enemas in the evening and in the morning until the waters are clear. Dinner on the eve of irrigoscopy is not allowed.

NB! In case of bleeding from the gastrointestinal tract or ulcerative colitis, administering enemas and taking laxatives before irrigoscopy are not allowed.

Decoding the research results should be carried out by a qualified radiologist, the final conclusion based on all data on the patient’s condition is made by the clinician who referred the patient for the study - a gastroenterologist, surgeon, proctologist, oncologist.

Examination of the liver (gallbladder and bile ducts), pancreas

Cholegraphy and cholecystography

The essence of the method: Holegraph?I- X-ray examination of the biliary tract by intravenous administration of hepatotropic radiopaque agents secreted by the liver with bile. Cholecystography- a technique for X-ray contrast examination of the condition of the gallbladder, performed to determine the position, size, shape, contours, structure and functional state of the gallbladder. Cholecystography is informative for identifying deformities, stones, inflammation, cholesterol polyps, gall bladder tumors, etc.

Indications for the study:

Biliary dyskinesia;

Cholelithiasis;

Calculous cholecystitis;

Gallbladder cancer;

Chronic cholecystitis;

Chronic acalculous cholecystitis.

Conducting research: cholegraphy performed on an empty stomach. Beforehand, the patient is recommended to drink 2–3 glasses of warm water or tea, which reduces the reaction to the procedure, and 1–2 ml of a radiopaque substance is administered intravenously ( allergy test), if there is no reaction after 4–5 minutes, pour in the remaining amount very slowly. Typically, a 50% solution of bilignost (20 ml) warmed to body temperature, or similar products, is used. For children, the drugs are administered at a dose of 0.1–0.3 g per 1 kg of body weight. Radiographs are taken 15–20, 30–40 and 50–60 minutes after injection with the patient in a horizontal position. To study the function of the gallbladder, targeted photographs are taken with the subject in a vertical position. If the images do not show the bile ducts 20 minutes after the administration of the radiocontrast agent, 0.5 ml of a 1% solution of pilocarpine hydrochloride is injected under the skin to cause contraction of the sphincter of the common bile duct.

Before cholecystography A survey x-ray of the right half of the abdominal cavity is taken. After x-raying, several photographs of the gallbladder are taken in different projections with the subject being examined in vertical and horizontal positions. Then the patient is given the so-called “ choleretic breakfast"(2 raw egg yolks or 20 grams of sorbitol in 100–150 ml of water), after which after 30–45 minutes (preferably serially, every 15 minutes), repeat images are taken and the contractility of the gallbladder is determined.

Contraindications, consequences and complications: cholegraphy and cholecystography are contraindicated in case of serious dysfunction of the liver, kidneys, cardiovascular system and hypersensitivity to iodine compounds. Side effects when using bilitrast, they are observed infrequently and are of a very moderate nature. They can be expressed in the form of a feeling of heat in the head, a metallic taste in the mouth, dizziness, nausea, and sometimes slight pain in the abdomen.

Preparing for the study: 12–15 hours before cholecystography, the patient takes bilitrust(organic iodine compound) or other contrast agent ( cholevid, yopagnost, telepac, bilimin etc.) in a dose of 1 g per 20 kg of body weight, washed down with water, fruit juice or sweet tea. Contrast agents (organic iodine compounds) can be taken by the patient not only orally, but also administered intravenously, less often through a tube into the duodenum. The night before and 2 hours before the examination, the patient cleanses the intestines with an enema.

Decoding the research results should be carried out by a qualified radiologist, the final conclusion based on all data on the patient’s condition is made by the clinician who referred the patient for the study - a gastroenterologist, surgeon, oncologist, hepatologist.

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