Mycoplasma pneumonia. Mycoplasma pneumoniae, IgG antibodies, quantitative, blood Diagnostic titer of antibodies for mycoplasma pneumonia

Description

Determination method Immunochemical (enzyme-linked immunosorbent) analysis.

Material under study Blood serum

Home visit available

Indicator of current or past Mycoplasma pneumoniae infection.

Mycoplasma pneumoniae is a common etiological agent of atypical pneumonia in children and adults. The proportion of mycoplasmosis among acute respiratory diseases that occur predominantly in the upper respiratory tract is 5 - 6% of the total number of patients, and in acute pneumonia - from 6 to 22% of all patients with pneumonia.

Mycoplasma pneumoniae is also associated with non-respiratory diseases, such as meningitis, encephalitis, pancreatitis, Stevens-Johnson syndrome, etc. IgG antibodies specific to Mycoplasma pneumonia appear later than IgM antibodies and persist for a much longer period (more than a year ).

IgM antibodies specific for Mycoplasma pneumonia appear soon after the onset of the disease, reaching peak levels after 1 to 4 weeks, then decline to undetectable levels over several months. A significant increase in IgG levels in consecutive samples taken at least 2 weeks apart may indicate ongoing infection or reinfection, even in the absence of IgM antibodies. Immunity is not stable, and cases of re-infection are possible.

Literature

Guide to infectious diseases with an atlas of infectious pathology. Edited by Yu.V. Lobzina, S.S. Kozlova, A.N. Uskova. www.infectology.spb.ru, St. Petersburg. 2000
Encyclopedia of Clinical Laboratory Tests, ed. N. U. Titsa. Publishing house "Labinform" - M. - 1997 - 942 p.
Materials for reagent kits.

Indications for use

Diagnosis of Mycoplasma pneumoniae infection.

Interpretation of results

Interpretation of research results contains information for the attending physician and is not a diagnosis. The information in this section should not be used for self-diagnosis or self-treatment. The doctor makes an accurate diagnosis using both the results of this examination and the necessary information from other sources: medical history, results of other examinations, etc.

The results are given in the following terms: “negative”, “doubtful”, “positive”. If the result is positive, the value of the positivity coefficient is displayed.*

Positive result:

current infection or reinfection with Mycoplasma pneumoniae.
past infection with Mycoplasma pneumoniae.

Negative result:

no infection.
early period of infection or long-term periods after infection.

* Positivity ratio (PR) is the ratio of the optical density of the patient's sample to the threshold value. CP - positivity rate is a universal indicator used in high-quality enzyme immunoassays. CP characterizes the degree of positivity of the test sample and can be useful to the doctor for the correct interpretation of the result obtained. Since the positivity rate does not correlate linearly with the concentration of antibodies in the sample, it is not recommended to use CP for dynamic monitoring of patients, including monitoring the effectiveness of treatment.

Answers:

Good afternoon, Maria. Because IgG antibodies to chlamydia pneumonia were not detected by ELISA, then you have not encountered it before. The detection of IgG antibodies to mycoplasma indicates that you have previously encountered it. To know whether you have it now, whether it is causing problems that require treatment, you need to undergo further examination and visit a doctor in person. Be healthy!

2011-01-18 16:32:16

Irina asks:

Hello, please tell me. I took tests and I have mycoplasma pneumonia IgG-3.02 IgM-1.63 The doctor said that this infection is transmitted only sexually and my husband and I need to be treated. And I read that this infection is also transmitted by airborne droplets. And if My mother lives with us, does she also need treatment? And I also have Escherichia coli Staphilococcus aureus Enterococcus faecalis/ She prescribed treatment according to the 1st day regimen - Sumomed 500 mg in the morning and evening. 2nd day - in the morning 3rd day in the morning 4th day morning 5th day in the morning. Fluzak 2nd day and 5th day. And I need Terzhinan suppositories. Tell me, is the treatment prescribed correctly? I want to get pregnant, but the doctor said that it’s impossible with mycoplasma. Thanks in advance for your answer

Answers Sergienko Alena Nikolaevna:

Hello, you need to do a culture to test the sensitivity of mycoplasma to antibiotics and then it will be treated. Regarding infection, the truth is on your side.

2011-01-17 19:25:31

Irina asks:

2014-02-06 17:14:50

Olga, 24 years old, asks:

Hello. I am worried about frequent colds (about 5 per year), periodically sore throat with redness of the back wall. Diagnosis of chronic tonsillitis. There is no sore throat, there is no high temperature, the plugs are not visible, on the third wash everything is clean, the tonsils are not large. The temperature lasts for about a year at 36.9-37.2. It rises throughout the day, mostly around lunchtime, but very rarely in the morning.
Examined
1. General blood test, for about two years the ESR has been increased from 20 to 35, with the norm being no more than 15. Sometimes leukocytes are slightly elevated (10 with the norm being up to 9)
2. Biochemistry is normal.
Rheumatoid factor is normal
C-reactive protein is normal
ASLO up to 500 at a rate of 0.01-200
There was a decrease to 200 with complex treatment (washing the tonsils, rinsing, antibiotics, bacteriophages), then an increase again.
3. Blood test for sterility is normal
4. Antibodies to antigens of opisthorchis, echinococcus, toxocar, trichinella IgG negative
5. Antibodies to cytomegalovirus IgG positive (93.8)
(indicators less than 0.5 negative
more than 1.0 positive)
6. Antibodies to cytomegalovirus IgM negative
7. Antibodies to the nuclear antigen of the Epstein-Barr virus IgG positive (32.10) (indicators less than 5 are negative; more than 20 are positive); Antibodies to the capsid protein of the Epstein Barr virus IgM negative.
8. PCR diagnostics
DNA of candida albicans, chlamydia pneumonia, streptococcus pneumonia, mycoplasma pneumonia, streptococcus pyogenes was not detected in the scraping.
9. A swab from the throat revealed staphylococcus aures 1*10 to 5 degrees
10. Antibodies to toxoplasmosis IgG and IgM negative
11. hormones T3, T4 free, TSH sensitive normal
12. Immunoglobulins G, M, E normal
13.Urine analysis is general and according to Nechiporenko the norm
14. Stool analysis norm
15. Ultrasound of the abdominal cavity, kidneys, thyroid gland, lymph nodes, mammary glands is normal
16. ECHO of the heart is normal, ECG is a moderate change in the myocardium
17. CT scan of the chest without pathologies
18. Consultations with a gynecologist, cardiologist, dentist, infectious disease specialist, rheumatologist, endocrinologist - everything is normal.
TELL! QUESTION
*Is there a test to determine the function of the tonsils?
* One doctor suggests removing tonsils based on the indications of ASLO, others advise waiting and treating.
* Is prolonged fever typical for tonsillitis? *Could it be related to decreased immunity?
WHAT OTHER Examinations would you recommend?

Answers Vasquez Estuardo Eduardovich:

Hello Olga.
The tests and the condition you described indicate a chronic inflammatory process with the beginning of a weakening of the immune system.
Answering your questions:
Is there a test to determine the function of the tonsils? - there are no specific ones, and we don’t see the feasibility.
Different doctors - different opinions and ways of fighting, there is no problem with that. We would agree with the second opinion.
Is prolonged fever typical for tonsillitis? - answer incl. Regarding immunity, we have already written to you above.
Now we don’t think any examinations are necessary, and we also don’t insist on asking your doctor. Examinations will be needed only periodically and at the direction and initiative of the treating physician.

2013-03-01 18:52:53

Daria Statinova asks:

Answers Shapoval Olga Sergeevna:

Hello, Daria. Considering the existing complaints of discharge and burning, associated pain and menstrual irregularities, most likely there is an untreated ureaplasma infection, identified back in 2009. There is a tactic when ureaplasma is actually identified as a conditionally normal component of the microflora of the genital tract (in 20% of women its healthy carriage is determined). In this case, treatment is not prescribed. However, if a woman has any complaints from the genitourinary system, a chronic inflammatory process, infertility, a complicated pregnancy, cervical erosion, treatment is definitely required. Although ureaplasma was not found in your tests, this is not a reason to calm down. Did you take the test correctly (do not use any antibiotics or vaginal suppositories for 2-3 days, it is better to take it on the 2-3rd day after the end of your period using PCR from the cervical canal and urethra, do not urinate 2 hours before taking the smear). I recommend repeating the ureaplasma PCR in another laboratory. But the identified EBV may indeed be the cause of the development of chronic fatigue syndrome, which you clearly have. I recommend adding vitamin therapy (B vitamins, vitamin C) and adaptogens (for example, echinacea) to the treatment complex. This syndrome most often develops in a group of people whose lives are subject to constant stress (think about how to reduce this factor), whose work is associated with computer radiation, who have insufficient physical activity (a wide choice of sports and relaxation techniques), and who are negatively disposed towards future life prospects (create positive motivation yourself or with the help of various psychotherapeutic techniques). Optimize your sleep and rest patterns, balance your diet, select adequate, interesting physical activity, and the treatment process will be more intense. Physiotherapeutic techniques also work well: healing massage, oxygen baths and cocktails, exercise therapy. As you can see, the range is quite wide and the best option is to think about undergoing spa treatment and then normalizing your daily schedule.

2012-01-19 06:05:05

Leila asks:

Good afternoon, I’m planning a pregnancy, I took PCR tests for infections in 2 laboratories, everything was negative. I took an ELISA test for infections and only mycoplasma was detected, IgG 0.512 when the norm was 0.318. Do I need treatment before pregnancy? By the way, 2-3 weeks before the test I got sick, had a runny nose and cough, but it went away in 2 weeks.
I haven’t passed Title M yet.
And is it necessary to examine the child (I have a 2-year-old son) to see if he can also have this infection. A year ago, when my son was suffering from bronchitis, he was tested for mycoplasma pneumonia and the result was negative.
Thank you!

Answers Consultant at the medical laboratory "Sinevo Ukraine":

Good afternoon, Leila. You have not been diagnosed with mycoplasma itself, but only class G antibodies to it. Those. There is no reason to talk about the presence of infection now. Test results are always evaluated in conjunction with clinical data; in addition, in order to have grounds to confirm a mycoplasma infection, re-test IgG to mycoplasmas in the same laboratory 2-3 weeks after the first test. If there is no increase in antibody titer, forget about the fact that you have been diagnosed. Be healthy!

2011-07-07 01:58:50

Ksenia asks:

Hello. I have been worried about a temperature of 37.0-37.3 for 10 months. First we treated pneumococcus 10 in 6. It was cured, but the temperature did not drop. I was tested for all infections, mycoplasma pneumonia was found to be positive by PCR, and by ELISA the indicators were IgG-14 (normal up to 10), IgA-22.3 (normal up to 10). Treated with vilprofen for 10 days. A month later I took a PCR test - negative, ELISA IgG-23, IgM-5.5. The temperature does not go away. The condition improved slightly after taking vilprofen. In addition to the temperature, persistent tonsillitis, pharyngitis, enlarged submandibular lymph nodes, and a strong reaction to cold are of concern. The swab from the throat is different, then streptococci SPP 10 in 6, then Nysseria 10 in 5. The tonsils were washed, I go to physio, the inflammation is relieved a little, but nothing completely goes away, there is a constant sore throat and sore throat. ENT says it can’t give a temperature, the throat is normal. Kidneys hurt from time to time. Ultrasound - grade 1 echogenicity of the parenchyma, all other urine tests, biochemistry are normal. The urologist says there is nothing wrong. Question: is it necessary to treat mycoplasma further and take antibiotics? there are symptoms, or you can wait and get tested again to see if the titer drops. Can she pass on her own, are these indicators high and what are they talking about? Thank you.

Answers Markov Igor Semenovich:

Hello, Ksenia. Mycoplasma (like pneumococcus before) has nothing to do with your temperature and does not need treatment. 2. The use of antibiotics is contraindicated for you. 3. Low-grade fever is associated with a chronic bacterial infection in the kidneys, which is confirmed by urine culture. Further treatment is an autovaccine prepared from bacteria isolated during bacterial culture.

2011-01-20 08:30:08

Elena asks:

Good afternoon I am 26 years old. I hope very much for your help. I have had a sore throat for 3 years (soreness, burning, rawness, lately mostly in the morning), constant fatigue (+ I have been taking antidepressants for 1.5 months, Valdoxan). There is a reflux disease (poor sphincter function, increased acidity). Currently I am working and studying.

I was tested 3 times for EBV+mycoplasma pneumonia+chlamydia pneumonia+cytomegalo virus. I got sick with the herpes virus.

How to treat EBV? I have taken antibiotics 7-8 times over the past 3 years. But they said nothing is prescribed against the virus and this is the first time they are encountering such a case when active EBV is detected several times. Diagnosis: infectious mononucleosis. 3 years and no treatment?! The cervical lymph nodes and the lymph nodes near the left breast are enlarged. I contacted ENT doctors and infectious disease specialists. What other specialist can I contact? What is the prognosis in such a situation?

The possibility of malignant formations is very scary.

Analyzes 07/08/2010

CMV IgM- neg 0.39 (ref CMV IgG- pos >
Analyzes 05.10.2010

Analyzes 12/16/2010
Chlamydia pneumonia IgA pos 46.395 (neg Chlamydia pneumonia IgM neg 0.19 (neg Chlamydia pneumonia IgG pos 198.222 (neg Mycoplasma pneumonia IgA pos 13.429 (pos >12) EIU
Mycoplasma pneumonia IgM pos 1.523 (pos>1.1) S/CO
Mycoplasma pneumonia IgG pos 216.356 (pos >45) EIU
HIV Ak+Ag neg 0.42 (ref CMV IgM- neg 0.348 (ref CMV IgG- pos >

I would be very grateful for your quick response.
Thank you in advance,
Elena

Answers Consultant at the medical laboratory "Sinevo Ukraine":

good day, Elena! And all this time you were treated only based on the results of these tests? Have you never conducted a PCR study? If this is the case, then it’s a shame, but you were treated incorrectly. If you continue to carry out repeated courses of antibacterial therapy, then not only your throat will begin to hurt. So, judging by the test results, you are a lifelong carrier of CMV and HSV type 1. These viruses will remain in your body forever; you cannot get rid of their presence. Most of the time, viruses sleep and do no harm. Occasionally, they can be activated and lead to the appearance of a rash, ARVI symptoms, etc. Before blaming a herpes virus infection, you need to reliably check its activity. This is very simple to do; you just need to use the PCR method to analyze blood (CMV, HSV 1), urine and saliva (CMV) for viral DNA. If there is DNA of viruses, go to a face-to-face appointment with an infectious disease specialist and carry out adequate antiviral therapy under his guidance. If there is no DNA of viruses, then the viruses are dormant, do not cause harm, and do not require treatment. You have not yet encountered HSV 2, you are not a carrier of this virus, the positive result obtained during the first study was a false positive. If you had a primary infection with HSV 2 then, you would now have IgG antibodies to this virus in your blood. And you see for yourself that you don’t have them. Now about VEB. Judging by the test results, you are really familiar with this virus, but if I were you, I would not say that you have been suffering from infectious mononucleosis for three years now. Let's figure it out. So, you have IgG antibodies to EBV nuclear antigen (EBNA IgG) in your blood. But antibodies of this class are usually detected in the blood only 1–3 months after the onset of infectious mononucleosis. Even after recovery, low titres of these antibodies in the blood remain for life. You do not have IgM to the capsid antigen (VCA) of EBV, and they are the marker of acute infection. Since there are no antibodies of this class, then there can be no talk of acute EBV infection (infectious mononucleosis). As for IgG to the capsid antigen (VCA), at a threshold level they can also be detected in the blood throughout life, after appearing in the blood in the first weeks after infection. And finally, IgM and IgG to early antigens (EA) are usually detected in the acute period of mononucleosis and circulate for about 2-3 months. Their longer circulation indicates a transition to a chronic form. In any case, you additionally need to conduct a PCR test of blood and saliva for EBV DNA. Only the presence of EBV DNA in your biological fluids can serve as confirmation of the activity of the process caused by EBV and serve as a reason for treatment (antiviral). In addition, I advise you to carry out a comprehensive diagnosis of dysbiosis, which you probably had before and significantly worsened after multiple courses of antibiotic therapy. Until you restore the local immunity of the mucous membranes and their normal composition of microflora, problems with your throat will not leave you. Be healthy!

2010-12-28 21:23:26

Elena asks:

Good afternoon I am 26 years old. I hope very much for your help. I have had a sore throat for 3 years and constant fatigue (I have been taking antidepressants for the 3rd week). I was tested 3 times for EBV+mycoplasma pneumonia+chlamydia pneumonia+cytomegalo virus. I got sick with herpes virus 1/2. HSV 2 is said differently, one doctor reported that infection has occurred. the second said that she was not infected. Perhaps there was an increase in the HSV 2 IgM titer due to viral replication, since HSV 2 IgG was absent in repeated tests, or on the verge.

How to treat EBV? I have taken antibiotics 7-8 times over the past 3 years. But this is an antibacterial treatment. But they said nothing is prescribed against the virus and this is the first time they are encountering such a case when active EBV is detected several times. What should I do, no one can help me. I visited a lot of doctors. What's the forecast? The possibility of malignant formations is very scary!!! What other specialist can I contact? I visited 3 infectious disease specialists, but no one prescribed antiviral therapy.

Analyzes 07/08/2010
HIV Ak+Ag neg 0.158 (ref HSV 1 IgM -neg 0.119 (neg 1.1) S/CO
HSV1 IgG- pos 3.122 (neg 1.1)S/CO
HSV2 IgM-pos 1.528 (neg 1.1)S/CO
HSV2 IgG -neg 0.758 (neg 1.1)S/CO
CMV IgM-neg 0.39 (ref CMV IgG-pos >500 (ref EBV VCA IgM-neg 0.014 (ref EBV VCA IgG-pos 10.643 (ref EBV EA IgM-pos 2.865 (ref EBV EA IgG-pos 1.235 (ref EBV NA IgG -pos 14.722 (ref
Analyzes 05.10.2010

HSV2 IgM-neg 0.507 (neg 1.1)S/CO
HSV2 IgG -neg 0.695 (neg 1.1)S/CO

Analyzes 12/16/2010

Chlamydia pneumonia IgA pos 46.395 (neg Chlamydia pneumonia IgM neg 0.19 (neg Chlamydia pneumonia IgG pos 198.222 (neg
Mycoplasma pneumonia IgA pos 13.429 (pos >12) EIU
Mycoplasma pneumonia IgM pos 1.523 (pos>1.1) S/CO
Mycoplasma pneumonia IgG pos 216.356 (pos >45) EIU

HIV Ak+Ag neg 0.42 (ref CMV IgM- neg 0.348 (ref CMV IgG- pos >500 (ref EBV VCA IgM- neg 0.1 (ref EBV VCA IgG-?
EBV EA IgM-pos 4.945 (ref EBV EA IgG-pos 1.332 (ref EBV NA IgG-pos 13.213 (ref
I would be very grateful for your quick response. I think that in my case, timely treatment is very helpful.

Thank you in advance,

IgG antibodies to the causative agent of respiratory mycoplasmosis (Mycoplasma pneumoniae) are specific immunoglobulins produced in the human body during the period of pronounced clinical manifestations of respiratory mycoplasmosis and are a serological marker of a current or recent disease.

Synonyms Russian

IgG class antibodies to Mycoplasma pneumoniae, class G immunoglobulins to Mycoplasma pneumoniae.

SynonymsEnglish

M. pneumoniae Antibodies, IgG, Mycoplasma pneumoniae Specific IgG, Anti-Mycoplasma pneumoniae-IgG.

Research method

Enzyme-linked immunosorbent assay (ELISA).

What biomaterial can be used for research??

Venous blood.

How to properly prepare for research?

Do not smoke for 30 minutes before the test.

More about the study

Mycoplasma pneumonia (sometimes called “atypical pneumonia”) constitutes up to 15-20% of all cases of community-acquired pneumonia. Sometimes they can lead to entire epidemics, especially in school-age children and in closed population groups, such as the military. The source of infection is both patients and carriers. Infection occurs by airborne droplets, the incubation period lasts 2-3 weeks. Symptoms of mycoplasma infection vary. In most cases, the disease is mild and is accompanied by cough, runny nose, and sore throat that persist for several weeks. When the infection spreads to the lower respiratory tract, headaches, intoxication, fever, and muscle pain occur. Pneumonia is most severely affected by young children, as well as people with weakened immune systems, such as HIV patients.

Making a diagnosis of “mycoplasma infection” is often difficult, so several research methods are used, in which serological tests play a leading role.

In response to infection with Mycoplasma pneumoniae, the immune system produces specific immunoglobulins: IgA, IgM and IgG.

The production of class G immunoglobulins to Mycoplasma pneumoniae does not begin immediately after infection, after about 2-4 weeks, but continues for a long period (a year or more).

The presence of class G immunoglobulins to Mycoplasma pneumoniae in the blood indicates an acute or past illness, a chronic inflammatory process or reinfection.

What is the research used for?

To confirm current illness (including reinfection) caused by Mycoplasma pneumoniae.
For the differential diagnosis of mycoplasma pneumonia and other infectious diseases of the respiratory tract, such as pneumonia caused by streptococci or staphylococci.
For the diagnosis of mycoplasma infection in chronic inflammatory diseases of the respiratory tract.

When is the study scheduled?

For symptoms of illness caused by mycoplasma (nonproductive cough that may persist for several weeks, fever, sore throat, headaches and muscle pain).
If a chronic or persistent form of Mycoplasma pneumoniae infection is suspected, manifested by frequent relapses.

What do the results mean?

Reference values

Result: negative.

CP (positivity coefficient): 0 - 0.8.

Reasons for negative results:

no infection,
the infection is too early, when the immune response has not developed.

Reasons for the positive result:

current or past mycoplasma infection,
chronic mycoplasma infection,
reinfection with Mycoplasma pneumoniae (in the absence of IgM).

What can influence the result?

The results of the analysis can be affected by disorders of the immune system, autoimmune diseases, and HIV.
Infectious diseases caused by other types of mycoplasmas, ureaplasma, contribute to a false positive result.

Important Notes

Diagnosis of Mycoplasma pneumoniae infection must be comprehensive - include data from the epidemiological history, clinical picture and other tests. Determination of immunoglobulins class M and G is mandatory.
Immunity to mycoplasma is unstable, re-infection is possible.

Mycoplasma pneumoniae, DNA [PCR]

Who orders the study?

Pediatrician, general practitioner, infectious disease specialist, pulmonologist.

Lenochka Kovtun, Woman, 23 years old

Good afternoon. I really hope for some advice or a little consultation. In August 2015, my son, 4.5 years old and 20 kg, fell ill. The cold was like a classic ARVI, runny nose, slight fever, dry cough. We were treated by a pediatrician, syrups, vasoconstrictor drops, and antipyretics if necessary (ibuprofen alternating with paracetamol). The runny nose went away, the temperature too, but the dry cough remained, the pediatrician prescribed all possible syrups, both mucolytics and antitussives. When listening to the lungs, there was hard breathing, there were no wheezes. There was a decision to take sumamed, after drinking it for 7 days, it did not give any results. We turned to the ENT specialist, he did not reveal any pathologies in his area. They sent me to an allergist, tested for allergens, immunoglobulin E, eosinophilic cationic protein, and dog hair (since there is a dog in the house), everything was negative. The allergist prescribed only a course of isoprinosine and tonsilotren. The cough remained. In September they took an x-ray and everything was clear. All this time, we were periodically observed by the pediatrician; various cough syrups were prescribed, but they did not bring relief. We went to an infectious disease specialist, having previously donated blood using the Ifa method for mycoplasma pneumonia, chlamydia pneumonia, whooping cough and parapertussis. The last two were not detected, but chlamydia and mycoplasma were positive. (Immunoglobulin M in both), the infectious disease specialist prescribed vilprafen solutab for 21 days. After drinking it and taking tests again, nothing has changed. The cough is just as dry and tearing. We were referred to a pulmonologist. The pulmonologist, in turn, prescribed inhalations with aminocaproic acid, Libexin, and Rulid for 14 days. While we were drinking Libexin, the cough decreased a little, but remained. In November 2015, my son fell ill with ARVI and we were taken by ambulance to the hospital with bronchitis, there were inhalations with pulmicort, bromhexine, cephalasporin antibiotics, drainage massage, and physical treatment. We were discharged and the cough continued. In December we re-tested, chlamydia pneumonia was positive in IGg, negative in IGm, it turns out we cured it, and mycoplasma was positive in IGM and positive in IGg. The pulmonologist prescribed a course of libexin and bronchomunal again. During treatment, we suffered from obstructive bronchitis 2 times, but the treatment was carried out at home. Having been tested again, mycoplasma is again positive in IGm and IGg. We contacted the center for allergy, immunology and lung diseases. They took an x-ray and everything was clear. The doctor prescribed macropen 175 mg. 15 ml 2 times a day. For 21 days. Now we are drinking, we have 2 days left to drink, but there is no change. A little about cough. It is dry, tearing, as if it is being squeezed out of itself, it happens at different times, maybe at night, in the morning the cough intensifies, as it feels like phlegm is collecting during the night and he is trying to cough it up. We were denied childhood neurosis; a neurologist examined us and said this was not his part. We are so tired of everything already; in total, the child has been coughing for 10 months, and there is no improvement. A bronchoscopy was suggested, but the doctor advised not to rush into making a decision and treat mycoplasma pneumonia, and then rely on the symptoms and repeated tests. We are walking in a vicious circle, asking for at least some advice. Thank you.

Hello! To treat acute chlamydial and mycoplasma infections, macrolide antibiotics and a replacement immunomodulator are used, for example, with antioxidants and vitamins in the form of rectal suppositories. You have already received more than one course of antibacterial therapy, but there is no positive dynamics. In terms of diagnostics - antitoxic antibodies to whooping cough and parapertussis, and, of course, bronchoscopy. A persistent cough can take up an entire pediatric appointment.