Analogs of tropicamide eye drops. Tropicamide - effective eye drops for diagnosis and treatment

Tropicamide eye drops are an ophthalmic agent that causes short-term mydriasis (dilation of the pupil), as well as paralysis of accommodation. Used for diagnostic purposes and for the treatment of certain eye diseases.

Composition and release form

Tropicamide - solution of eye drops 0.5 and 1.0%, contains:

• Active ingredient: tropicamide 5.0 or 10.0 mg;
• Excipients: disodium edetate dihydrate, sodium chloride, benzalkonium chloride, hydrochloric acid, water.

Package. Plastic bottles of 10 ml.

pharmachologic effect

Tropicamide is an M-anticholinergic drug that can block the receptors of the ciliary body and the iris sphincter, which causes short-term mydriasis, and increasing the dose causes paralysis of accommodation (cyclopegia). The solution may slightly increase the pressure inside the eye.

The state of mydriasis develops after 5-10 minutes, reaching its maximum at 20-45 minutes. The maximum pupil dilation lasts for about an hour. The original pupil size is restored after six hours.

The percentage of absorption of tropicamide through the lacrimal glands is relatively high, so systemic side effects may occur.

Indications for use

• For diagnostic purposes (carrying out ophthalmoscopy, determining refraction).
• Prevention of the development of synechiae (as an element of complex therapy for inflammatory eye diseases).
• Refractive study (to achieve paralysis of accommodation).

Directions for use and doses

Conjunctival application.

To dilate the pupil for diagnostic purposes, Tropicamide 0.5% is applied from 1 to 3 drops over 10 minutes. After which ophthalmoscopy can be performed.

When determining refraction, it is necessary to instill Tropicamide 0.5% 6 times drop by drop for 6-12 minutes.
For medicinal purposes, Tropicamide 0.5% is instilled up to 6 times daily.

Tropicamide 1% is used in 1-2 drops of solution to achieve the effect of paralysis of accommodation (cyclopegia) when studying refraction. Instillations are repeated after 5 minutes. To prolong the effect of mydriasis, you can additionally instill 1 more drop if the examination lasts longer than 25 minutes.

Contraindications

• Individual hypersensitivity.
• Angle-closure glaucoma.
• Increased intraocular pressure.

Tropicamide is used with extreme caution during pregnancy, breastfeeding and in infants.

Side effects

• Local allergic reactions, high intraocular pressure, photophobia, reduced visual acuity.
• Headache, psychosomatic reactions, hypotension, tachycardia, hyperthermia, dysuria, convulsions, dry mouth.

Overdose

Unlikely to be used topically in accordance with the instructions.

Drug interactions

Adrenergic stimulants can enhance, and m-cholinergic stimulants weaken the effect of tropicamide. Tricyclic antidepressants, amantadine, phenothiazines, quinidine and antihistamines can worsen the side effects of tropicamide.

special instructions

The drug contains the preservative benzalkonium chloride, which can be absorbed by soft contact lenses. Therefore, their use is not recommended during treatment with tropicamide.

Hard contact lenses must also be removed before instillation and should be put on only 15 minutes after applying the drug.

Most people are accustomed to eye drops being used to treat diseases. However, there are drugs whose main purpose is to prepare patients for diagnostic procedures and studies. Tropicamide is one such remedy. This is exactly what we will talk about in this review.

Composition and effects on the body

The active component of the drug is a substance of the same name, tropicamide. The product also contains auxiliary ingredients such as:

• sodium chloride (better known as table salt);
• EDTA-sodium;
• hydrochloric water;
• benzalkonium chloride;
• distilled water.

The principle of action of Tropicamide is as follows. Vessels, tissues, and organs contain so-called M-cholinergic receptors. These receptors carry a number of physiological functions, from muscle contraction to increased secretion in the glands. However, in nature there is a class of substances that can block the functioning of M-cholinergic receptors. Such substances are called M-anticholinergics. The hero of our article belongs to them.

Tropicamide eye drops block cholinergic receptors, which are contained in the iris of the eye. This causes the eye muscles to relax for a while. Along with relaxation, the so-called mydriasis occurs - dilation of the pupil. At the same time, the eye muscles responsible for its narrowing are simultaneously blocked, which in medicine is usually called paralysis of accommodation. Thus, eye drops maintain the pupil in a dilated state.

The drug is used to dilate the pupil during diagnosis and treatment.

Does Tropicamide help with myopia? Yes. The medicine relieves spasm of accommodation, which helps to partially improve vision.

Manufacturer and release form

The drug is produced by the Romanian company Rompharm.

Tropicamide is available only in the form of eye drops. The medicine is a colorless transparent liquid. The medication is packaged in polyethylene dropper bottles with a capacity of 5 ml and sold in cardboard boxes with instructions for use.

Storage conditions: temperature within 15-25 degrees Celsius; keep in a dark place, protected from light. Shelf life - 3 years, after opening - 4 weeks.

The average cost of Tropicamide is 100 rubles. To purchase the drug, you must present a prescription from a doctor: in large dosages, Tropicamide causes a narcotic effect.

Indications

Tropicamide is used for diagnosis and before certain operations. Indications for use may include:

• lens surgery;
• surgery on the retina and vitreous body;
• retinal laser therapy;
• the need for paralysis of accommodation to study refraction (anatomical feature of the eye apparatus that causes myopia or farsightedness);
• the need for mydriasis during examination of the fundus and lens.

Tropicamide is not widely used in the field of therapy. But still, it is used to treat inflammatory eye diseases.

The medicine is prescribed to patients after surgery to prevent adhesions, also known as synechiae (when the iris sticks to the cornea or lens).

Drops should be instilled into the lower part of the conjunctival sac (the space between the eyelids and the eyeball). The dosage depends on the purpose:

• For diagnostic procedures, 1 drop for a 1% solution or 2 drops for a 0.5% solution will be sufficient. An examination can be carried out 10 minutes after instillation.
• To determine refraction, you need to drip the medicine 6 times, 1 drop each. There should be an interval of 6-12 minutes between procedures. Half an hour to an hour after the onset of paralysis of accommodation, you can begin the examination.
• For therapeutic treatment, the dosage is prescribed by the attending physician.

A pipette or a special dropper that comes with the drug will help you control the dose.

When buying medicine, pay attention to the dosage!

Can Tropicamide be used for children? Yes, but adhering to certain rules. When treating children under 6 years of age, only 0.5% drops are used, which are diluted with saline to a concentration of 0.25%. The resulting solution is perfect for a child and will not cause side effects.

Important! If you use Tropicamide on a newborn, you need to be especially careful. The drug may affect the central nervous system.

Before you start using it for pregnant women, you need to consult a doctor to assess how necessary the drug is, and whether it can be replaced with analogues. The use of Tropicamide while breastfeeding is not recommended.

Contraindications

Tropicamide should not be used in patients who suffer from or are prone to glaucoma (for example, have a too narrow anterior chamber angle). Otherwise, it can only worsen the patient's condition. Tropicamide should not be prescribed to those who have increased sensitivity (sensitivity) to the active substance.

Side effects

If you ignore contraindications or overdose, side effects may follow. The most common of them are photophobia, temporary vision problems, and increased intraocular pressure.

Side effects can affect not only the organs of vision. The drug can also negatively affect the central nervous system. Possible headaches, changes in behavior, manifestation of psychosomatic symptoms (alertness, aggressiveness, emotionality, etc.). This is especially true for teenagers and children with unstable mental health.

Side effects can also affect the cardiovascular system and manifest themselves in the form of tachycardia, respiratory and circulatory failure (shortness of breath, dizziness, etc.).

When using Tropicamide, allergies, dry mouth, and vomiting are possible.

Reviews will help you get useful information about the drug.

Igor from Tver writes:

“I’ve had problems with my eyes since school. I recently went to work where good eyesight is required. On the recommendation of the attending physician, Tropicamide began to drip. It feels like it has gotten better. I have been using the drug for a couple of weeks now. The product is quite cheap. I haven’t noticed any significant disadvantages yet.”

Victoria, mother of 3-year-old Dima from Minvod, shares:

“When the doctor prescribed Tropicamide drops for my child due to eye spasms, I was afraid of the list of side effects and became wary. The doctor calmed me down and told me how to use the medicine. I started giving the drug to my baby. The first results were not long in coming. The drops relax the eye muscles, which has a positive effect on the child’s vision. The only drawback is that the drug causes a burning sensation, so the baby may be capricious.”

Dr. Nikolai Alekseevich Krasnov, an ophthalmologist of the highest category from Tolyatti, recommends:

“From personal experience I can say that Tropicamide is indispensable in preparation for diagnostic procedures. The medicine, due to its mydriatic effect, is quite effective. The therapeutic properties of the drug are another plus. “I have repeatedly prescribed drops to treat eye inflammation.”

Analogs

Analogs of Tropicamide - drugs that also block M-cholinergic receptors and dilate the pupil can be divided into two groups. The first is products that are similar in composition. These include:

• Mydriacyl. The medicine is available in the form of eye drops. The average cost of Midriacil is 200 rubles per bottle with a capacity of 15 ml.
• Midrimax. They contain not only tropicamide, but also phenylephrine. The average price is 270 rubles per 5 ml bottle.

The second group includes drugs similar to Tropicamide in action, but with a different active ingredient. This group includes:

• Irifrin. The active substance is phenylephrine hydrochloride. The drug increases the amount of norepinephrine. Possessing alpha-adrenergic activity, it is capable of dilating the pupil when used locally. The expansion process can take anywhere from 10 minutes to an hour. The effect lasts up to 6 hours. In most pharmacies you can buy the drug for 550 rubles (5 ml bottle). Among the advantages of the drops one can note their high efficiency. Disadvantage: possible side effects.

Analogue of Tropicamide - Irifrin.

• Atropine. Extremely powerful analogue. The effect of pupil dilation lasts 7-10 days. At the same time, the main disadvantage of the drug is a significant number of contraindications and side effects. Because of this disadvantage, doctors today prescribe Atropine less and less. It is prohibited to use the drug on your own. Treatment should be carried out under the supervision of a specialist. Price - 50 rubles for 5 ml.
• Cyclomed. Works in a more gentle mode. After use, the drops cause virtually no side effects. The active ingredient is cyclopentalate, which also belongs to M-anticholinergic agents. The cost of the medicine is 575 rubles (5 ml bottle).
• Mezaton. The active ingredient is phenylephrine. The cost of the product is about 50 rubles for 10 ampoules.

Conclusion

Tropicamide is a mydriatic that is successfully used in ophthalmology. It does not have widespread therapeutic use, but is often useful in various diagnostic procedures and studies. The product can be used to treat children. Pregnant women are not recommended to use the drops.

Alexander Rekhlitsky

ophtalmolog.ru

Tropicamide

Tropicamide (Latin name Tropicamidum) is a drug for artificially dilating the pupil (mydriasis). It is used in ophthalmology for diagnostic and therapeutic purposes. It has eye side effects that may temporarily impair vision.

Download instructions

The composition of eye drops includes the active substance:

• Tropicamide - 5.0 mg/10.0 mg

Excipients:

• Sodium chloride - 7.0 mg
• Disodium edetate - 0.5 mg
• 50% benzalkonium chloride solution - 0.2 mg, equivalent to 0.1 mg benzalkonium chloride
• hydrochloric acid 1 M or sodium hydroxide 1 M - up to pH 4.0–5.8
• Water for injections - up to 1 ml.

Tropicamide is a clear, colorless liquid.

Tropicamide is produced in the form of eye drops 0.5% and 1%, 10 ml each in a polymer dropper bottle. Instructions for use of the drug along with the dropper bottle are located in a cardboard box.

Instructions for using the dropper bottle are printed on the packaging.

Tropicamide is an m-cholinergic receptor blocker; it causes blocking of m-cholinergic receptors in the iris sphincter and ciliary muscle. This leads to the development of mydriasis (dilation of the pupil) and paralysis of accommodation. The mydriatic and cycloplegic effect of the drug is much shorter than that of atropine.

Tropicamide has less effect on intraocular pressure, but its use may increase ophthalmotonus.

The development of mydriasis occurs 5–10 minutes after instillation and reaches its maximum effect by 15–20 minutes. The pupil remains dilated for 1–2 hours.

To create paralysis of accommodation, multiple instillations of the drug are needed. After 2-fold instillation of a 1% percent solution, on average, after 25 minutes, maximum paralysis of accommodation occurs and lasts 30 minutes. After 3 hours, the effect disappears, accommodation is restored.

The disappearance of all effects of the product occurs on average within 6 hours.

When instilled into the conjunctival cavity, a small part of the drug is absorbed systemically, mainly in the elderly and children.

Pupil response to light is the natural reaction of the eye to regulate the amount of light entering the retina. Tropicamide dilates the pupil and holds it open for a short time. Ophthalmologists use Tropicamide for diagnostic and therapeutic purposes:

• Carrying out an examination of the fundus of the eye - ophthalmoscopy
• To study the refraction of the eye
• Before eye surgery to dilate the pupil (cataract removal, retinal and vitreous surgery)
• Before laser operations - laser coagulation of the retina
• In the complex treatment of inflammatory eye diseases in combination with other drugs
• After operations to prevent the formation of synechiae

Tropicamide is a specific drug. There is no reason for a patient to prescribe it for self-medication. Only an ophthalmologist can prescribe tropicamide.

The following conditions require caution or discontinue use of Tropicamide:

• Glaucoma
• Angle-closure glaucoma
• Mixed primary glaucoma
• Predisposition to glaucoma (narrow anterior chamber angle profile, shallow anterior chamber)
• Hypersensitivity to the components of the drug

Tropicamide 1% is contraindicated in children under 6 years of age; a 0.5% solution can be used.

If you have one or more of the above contraindications, you should consult a doctor before taking the drug.

With extreme caution:

• With increased ophthalmotonus
• If the anterior chamber is not deep enough
• For inflammatory eye diseases, because hyperemia significantly increases transconjunctival systemic absorption of the drug.

There are no studies of the drug on the effect on fertility when applied topically.

Pregnancy

There is insufficient data on the use of the drug in pregnant women. It is not recommended to use the drug during pregnancy.

Breast-feeding

There is no data on the extent of penetration of tropicamide or its metabolic products into the milk of a nursing woman. The risk for a breastfed infant cannot be excluded.

The decision to stop breastfeeding or to suspend treatment with tropicamide is made based on an analysis of the benefits of breastfeeding for the child and the benefits of using tropicamide for the woman.

A child under 6 years of age can only use a 0.5% solution of tropicamide.

A 1% solution of tropicamide can be used in children over 6 years of age.

You should not combine the use of the drug with wearing soft or hard contact lenses. It is necessary to remove contact lenses before instilling the drug. You can put on lenses no earlier than 15 minutes after instillation.

According to the frequency of occurrence, side effects according to the WHO classification are divided into:

• Very rare - less than 1/10000 cases
• Rare - from 1/10000 to 1/1000 cases
• Uncommon - from 1/1000 to 1/100
• Often - from 1/100 to 1/10
• Very often - more than or equal to 1/10
• Frequency unknown - cannot be estimated from available data

The following side effects have been reported with unknown frequency:

• Photophobia
• Feeling of blurred vision
• Eye pain
• Redness and irritation of the eyes

Systemically:

• Nervous system - headache, dizziness
• Cardiovascular system - decreased blood pressure, fainting
• Digestive system - feeling of nausea
• Skin - rashes
• Local and general reactions: prolongation of mydriasis

Pupil dilation and accommodative paralysis may lead to local side effects such as photophobia and blurring. There may be an increase in ophthalmotonus, the appearance of allergic reactions, short-term burning and pain after instillation, redness and swelling of the conjunctiva.

In patients predisposed to angle-closure glaucoma, cycloplegic drugs may increase intraocular pressure and cause anterior chamber angle closure.

The toxic effect of anticholinergic drugs can be manifested by redness of the skin, dry mucous membranes, dry skin, increased heart rate (tachycardia), decreased secretion of sweat glands, decreased ability to moisturize the oral mucosa (dry mouth), decreased gastrointestinal motility (gastrointestinal tract), constipation , urinary retention, decreased secretory function of the lacrimal, nasal and bronchial glands. Severe adverse reactions occur with hypotension with rapidly progressive respiratory failure.

In pediatric practice, the appearance of psychotic reactions and behavioral disorders is possible, especially in childhood. In children, rashes may appear, and abdominal bloating in newborn patients.

There have been cases of cardiopulmonary collapse in children using drugs of this class.

If side effects described in the instructions develop or worsen, or if new ones appear, immediately notify your doctor.

For diagnostic use, Tropicamide is instilled locally, 1–2 drops of a 0.5% solution of eye drops 15–20 minutes before the examination.

To check and determine the refraction of the eye, instill 1–2 drops of a 1% solution of the drug 2 times a day with an interval of 5 minutes. In order to prolong the effect, it is possible to add another instillation.

In order to reduce the risk of systemic side effects, it is recommended to clamp the nasolacrimal duct after instillation by pressing and holding the point in the inner corner of the eye for several minutes.

Attention! Children under 6 years of age can only use a 0.5% solution of tropicamide!

If the drug gets into your eyes in excess, rinse your eyes with warm water.

Topical application is associated with general toxicity, especially in children - redness and dryness of the skin (children may have a rash), blurred vision, irregular and rapid pulse, feeling of heat, tachycardia, bloating in newborns, convulsions, hallucinations, loss of neuromuscular coordination .

Symptomatic and supportive therapy is necessary. Children of the younger age group need to moisturize their skin. In case of accidental ingestion, induce vomiting and perform gastric lavage; in severe cases, physostigmine may be prescribed.

The anticholinergic effect of tropicamide may increase when used together with other drugs that have an anticholinergic effect - for example: amantadine, tricyclic antidepressants, antipsychotics, phenothiazine derivatives, butyrophenone.

When using more than 1 local ophthalmic drug, at least 5-minute intervals between instillations must be observed. Eye ointments are used last.

The use of Atropine carries a particular risk in certain everyday situations.

Tropicamide is used only for instillation into the conjunctival cavity.

Do not touch the tip of the dropper bottle to other surfaces to avoid contamination of the dropper bottle and the solution.

After each use, you need to close the dropper bottle.

The use of tropicamide may increase eye pressure. Particularly in older people, the possibility of undiagnosed glaucoma must be taken into account. Before starting therapy, it is necessary to measure the pressure of the eye, conduct an examination to assess the depth of the anterior chamber and the nature of the profile of the anterior chamber angle.

Before using the drug for diagnosis, you should inform the patient or accompanying persons about short-term visual impairment and photophobia.

The development of tropicamide-induced psychomotor reactions and behavioral disorders in people with hypersensitivity to anticholinergic drugs is possible.

Caution is especially important in children and people with hypersensitivity to belladonna alkaloids (belladonna), as this is associated with a higher risk of general toxic effects on the body (details in the section on side effects).

Application in pediatric practice

The use of tropicamide in children, including infants, can be dangerous due to the possibility of disorders of the central nervous system. Excessive administration of the drug to children may cause the development of symptoms of systemic toxicity.

Particular caution should be exercised when prescribing the drug to newborns, children of a younger age group, premature babies, children with Down syndrome, brain damage and spastic paralysis.

It is necessary to warn the child’s parents about the toxic effect of the drug when taken orally. After taking the medicine, it is recommended that parents and children wash their hands. Accidental ingestion of the drug may have a toxic effect, which is important to consider when used in children. It is necessary to ensure that the hands of the child and parents are clean when using the medicine.

Impact on the ability to drive vehicles and operate machinery

Drowsiness, blurred vision and photophobia may occur when using tropicamide. After using the drug, it is not recommended to engage in activities that require increased attention and reaction speed, or drive vehicles until vision is completely restored, which usually occurs 6 hours after using the drug.

Dispensed only with a doctor's prescription.

Store at a temperature not exceeding 15º C in a place protected from light.

Two years from the date of release of the drug (indicated on the packaging). After opening, the shelf life of the drug is 30 days. Do not use a drug that has expired.

Atropine eye drops dilate the pupil, which is used in the diagnosis of eye diseases, as well as for medicinal purposes. More details

Before the operation to change the lens, the doctor prescribed tropicamide drops, as he explained for the operation. It stung a little, but nothing criminal, and after about 10 minutes blurriness appeared in the eyes and it was unpleasant to look at the light. I was surprised when I saw pupils of different sizes in the mirror)

I have had mild myopia since I was 18 years old. She doesn't bother me much, she's already used to it. It would seem like a very small deviation, but life changes significantly! Well, as I already said, I’m used to my disadvantage, but when I’m doing needlework or working hard at the computer, and even against a nervous background, then turn out the lights and throw a grenade. My -0.75 increases so much that I can’t even see my own pedicure!!! But I’m a shot sparrow and I’m starting to drip the savior - TROPICAMIDE. The drops sting, but I’m ready to be patient in order to see at least my -0.75. The ophthalmologist prescribed them to me and told me to take them when such a problem happens to me. Miracle drops! I advise with peace of mind)

Eternal uveitis has plagued me since I was a student. Antibiotics, hormones and mydriatics are my eternal companions. For the last three exacerbations, I took tropicamide drops 4 times a day, prescribed by my doctor. The bottle is very light and small, 10 ml, economical, colorless and odorless drops. The bottle is initially sealed, you need to screw the cap all the way and screw it on tightly and the hole is ready and from that very moment the drops are good for 1 month. Drops are useful especially for uveitis.

I work a lot with the computer and read a lot, and this, as you know, greatly tires the eyes. At the appointment, the doctor, given the high visual load on the eyes, advised me to take tropicamide. Drops dripped them every day at night for more than a month. The effect is positive. Perfectly relaxes the eyes, after sleep the vision, God willing, is excellent.

My vision began to deteriorate sharply, so I went to the doctor. She wrote out a prescription for drops and told me to take them 2 times a day. It's called Tropicamide. The drops have many disadvantages - you can’t buy them without a prescription, after opening they are only good for 1 month, they sting, it’s impossible to focus on your phone, book, letter, the light hurts your eyes. Advantages: reasonable price and effective use. Choose for yourself.

Prices for tropicamide eye drops range from 74 rubles to 163 rubles.

The drug is available with a prescription, so it is better to buy it in pharmacies. Online pharmacies make it possible to book it on the website and buy it at the nearest pharmacy.

MEZ develops and produces the most important drugs for the treatment of eye diseases.

The company implements the highest international standards for the production and quality control of medicines - GMP. Effective and safe MEZ medicines are available to the general population and successfully compete with foreign analogues

More details

www.vseozrenii.ru

Tropicamide eye drops - use according to instructions

Some medications used in ophthalmology were created for good purposes, but sometimes they are used for completely different purposes. Among such drugs we can name Tropicamide eye drops, the instructions for which say the following...

Brief characteristics of the drug

Tropicamide is a drug that dilates the pupil. This effect is used to relieve spasm of accommodation, conduct examinations, operations, and in complex treatment of diseases of the anterior part of the eye. The main active ingredient is tropicamide (M-anticholinergic). Excipients:

1. Sodium chlorides and benzalkonium.
2. Edetate disodium dihydrate.
3. Hydrochloric acid.
4. Purified water.

Eye drops are produced in the form of a solution of 0.5 or 1% in plastic dropper bottles of 5 or 10 ml. Instructions are included in the packaging. They are dispensed from pharmacies with a doctor's prescription. Average price: 65 rubles.

The principle of action of Tropicamide: blocking M-cholinergic receptors of the ciliary (ciliary) body and circular muscles of the iris, paralysis of accommodation, rapid and short-term dilation of the pupil (mydriasis). The drug begins to act 5-10 minutes after a single installation, the maximum effect is achieved after 15-20 minutes and lasts for 1 hour if a 0.5% solution was instilled, 2 hours - when a 1% solution was instilled. Normal pupil function is restored after 3-5 hours.

Through the conjunctiva, Tropicamide easily penetrates into the ocular tissues; some of it enters the nasal cavity through the nasolacrimal duct, from where it is absorbed into the general bloodstream. This contributes to some side effects.

Drops can cause an increase in eye pressure, so they should not be used alone!

Indications, regimen of use and contraindications

Tropicamide is prescribed for different purposes:

• Diagnostics. If you need to examine the lens or fundus of the eye.
• Operation. The drug is instilled into the eyes during surgery of the retina, lens and vitreous body; retinal laser therapy.
• Therapy. The solution is used in the complex treatment of eye diseases (keratitis, iridocyclitis, uveitis); after operations to prevent the occurrence of synechiae; to relieve spasm of accommodation in myopia.

Tropicamide eye drops should be used only as prescribed by your doctor! The frequency of installations and duration of use should be determined by him. In general, the instructions recommend the following use: to dilate the pupil, instill 1 drop of a 1% solution or 2 - 0.5% into the conjunctival sac. If necessary, the procedure can be repeated after 10-15 minutes.

Children can only instill a 0.5% solution. To reduce the risk of side effects when treating ocular inflammation and spasm of accommodation, it is recommended to instill drops before bedtime. To reduce the likelihood of the drug getting into the nose during installation, it is recommended to press the skin near the inner corner of the eye with your finger.

Contraindications to the use of Tropicamide are: increased eye pressure, glaucoma and intolerance to the components of the drug. These eye drops are used with caution in infants and the elderly, during pregnancy and breastfeeding.

Side effects and other information

The use of Tropicamide ophthalmic drops may be accompanied by:

1. Eye irritation: discomfort, redness, watery eyes.
2. Temporary impairment of visual acuity.
3. Increased intraocular pressure.
4. Photophobia, photophobia.

In addition, drops can cause systemic reactions such as weakness, nausea, headache, dizziness, and arrhythmia. Symptoms of overdose develop if the dosage regimen is not followed - instillation of higher doses, intravenous administration. This may be speech or motor agitation, rapid pulse, loss of orientation, dry mucous membranes, hallucinations.

If we talk about drug interactions, the effect of Tropicamide is enhanced by antiallergic and anticholinergic drugs, MAO inhibitors, and benzodiazelines. Adrenergic blockers weaken. When used simultaneously with haloperidol, glucocorticosteroids, nitrites and nitrates, the risk of increased eye pressure increases.

These eye drops are popular among drug addicts because they are quite affordable. But it only seems so... The price for their intravenous use and short-term pleasure is irreversible damage to all internal organs!

Tropicamide should not be dropped directly onto contact lenses. On the day of application, it is not recommended to drive any vehicle or perform potentially hazardous work. The shelf life of the drops is 3 years. Once opened, it can only be used within a month.

Video about Tropecamide - useful for parents to know:

What do you think about this drug, since it is often used by drug addicts to get high? We are waiting for your answers and feedback in the comments to the article!

zorsokol.ru

Tropicamide eye drops: properties and rules of use

In some cases in ophthalmology it is necessary to achieve a specific effect in which the pupil dilates. This is especially necessary when conducting any diagnostic studies to correctly determine the disease. One of the most frequently used drugs in this practice is Tropicamide, which, moreover, has a relatively low cost.

Description of the drug

Tropicamide is currently available only in the form of a solution for eye drops and is a clear and colorless liquid. The active component of the drug is tropicamide, but in addition to it, the composition contains sodium chloride, purified water, hydrochloric acid, sodium ETDA and benzalkonium chloride.

The concentration of tropicamide in these eye drops can be 0.5% or 1% depending on the release version. The composition is sold in ten milliliter plastic packaging with a dispenser. The kit also includes a cardboard box and a paper insert with description and instructions.

The drug is available by prescription through pharmacy chains.

The drug should be stored at room temperature out of the reach of children. The shelf life of unopened packaging is three years, and if opened it is no more than four weeks.

The drug belongs to the class of M-anticholinergics or mydriatics. They have an active effect on the sphincter, which is responsible for the width of the pupil of the eye. By expanding it, the active substance blocks the possibility of its reverse narrowing, due to which the effect persists for a long time and allows the necessary diagnostic procedures to be carried out.

The effect occurs five to ten minutes after instillation. The peak effect of the substance occurs between the seventeenth and twentieth minutes and lasts for an hour. The effect completely disappears five hours after the procedure.

It is highly not recommended to use the drug unless absolutely necessary, since it has a number of specific side effects.

Application

It is important to use the drug only as prescribed by a doctor in the dosages suggested by the ophthalmologist or the instructions. When used in combination with other medications for the treatment of diseases, it must be instilled one or two drops up to six times a day. In order to determine the degree of refraction - as necessary, to dilate the pupil - up to two times a day with an interval of at least fifteen minutes.

Before direct instillation, it is necessary to carry out basic hygiene procedures, wash your hands, face and rinse your eyes. It is not recommended to touch the skin or mucous membranes with the dispenser, especially when treating inflammatory diseases.

Before using the drops, contact lenses (if any) must be removed. You can put them back on only twenty minutes after the procedures.

Indications

The use of Tropicamide provides great opportunities in the field of research and treatment of diseases of the visual apparatus. Most often, drops are used for:

The medication is also effective for changing the width of the pupil before retinal surgery and lens replacement.

Contraindications

The drug is not used in cases of severe glaucoma, intraocular hypertension, or in case of too high sensitivity to the main components of the composition. Driving a vehicle or engaging in any activity that requires particularly increased attention and concentration is not recommended during therapy.

During pregnancy

During pregnancy, Tropicamide can be used with caution and only under the supervision and control of the attending physician. An important condition in this case is the high risk of damage to the expectant mother’s visual organs in the absence of treatment. Monitoring is also necessary during the breastfeeding stage.

For small children

The drug is actively used in pediatrics under close supervision. For children under six years of age, it can only be shown with a concentration of the active substance of 0.5%. Therapy for newborns is also possible, but some neurological disorders may occur.

Possible complications caused by the drug

An overdose of the solution is possible when taken orally. With this phenomenon, the following symptoms may be observed:

• Dry skin and mucous membranes;
• Abnormally high degree of arousal;
• Rapid heartbeat (tachycardia, arrhythmia);
• Cramps.

If these signs occur, it is necessary to perform gastric lavage, take Physohistamine and activated charcoal and immediately consult a doctor. Local use of the drug does not imply overdose.

The drug enhances the effect of antihistamines and antidepressants, as well as drugs that contain quinidine. An increase in intraocular pressure is possible when used together with Disopyramide, Haloperidol, nitrites, nitrates and glucocorticosteroids.

Major side effects with normal use include:

• Allergic reactions;
• Fear and intolerance to light;
• Headaches and dizziness;
• Decreased visual acuity;
• Dry mouth and dry mucous membranes;
• Changes in intraocular pressure.

If allergic reactions or increased side effects occur, you should stop using Tropicamide and consult a doctor. Excessively large dosages of the solution may increase the risk of complications.

Analogs

Currently, a large number of analogues, more expensive and cheaper, are produced. When selecting them, it is necessary to take into account not only the price factor, but also contraindications and possible hypersensitivity to the components of the formulations. Today in ophthalmology such drugs as Midriacil, Cyclomed, Atropine, Irifrin are actively used.

If the ophthalmologist prescribed Tropicamide for treatment, it is not recommended to choose analogues of the drug on your own. Before doing this, you should consult your doctor. Consultation is also needed if it is necessary to combine Tropicamide with other medications and traditional medicine.

Video

conclusions

Medicines such as Tropicamide have a wide spectrum of action: they are used as an adjuvant for therapy, surgery, prevention and comprehensive examination. These eye drops are prescribed most often due to the wide range of application possibilities, a small number of contraindications and side effects. In addition, they can be used during pregnancy and lactation, as well as for the treatment of diseases of children from birth.

Eye diseases often deprive a person of the ability to normally perceive the world around him. Naturally, in such cases it is necessary to contact an ophthalmologist for a thorough examination. In order to take a closer look at the condition of the eyeball, the doctor may prescribe special medications to prepare the patient for the examination. One such medicine is Tropicamide. The instructions for use (we will look at analogues later) will tell you all the information that will be of interest to people with vision problems.

General description of the drug

This medicine is intended for topical use, that is, to be dropped into the eyes. "Tropicamide" (analogues of the drug contain the same active substance) well blocks M-cholinergic receptors, that is, receptors of the iris and This helps not only to diagnose the disease, but also to carry out surgical intervention, as it causes paralysis of accommodation and dilation of the pupil.

"Tropicamide" is sold (analogs of this drug may cost less and are intended for other purposes) in dropper bottles. The volume of the bottle is 5 ml. The main active ingredient is tropicamide. 1 ml of half-percent liquid contains 5 mg of the main substance. In addition, the drug contains the following components: benzalkonium chloride, sodium chloride, hydrochloric acid, sterilized water, and disodium salt of ethylenediaminetetraacetic acid.

Mechanism of action

"Tropicamide" (analogues can have completely different effects on the body) paralyzes the accommodation of the eye and dilates the pupil. This helps to examine the fundus of the eye without any problems using devices. In addition, paralysis makes surgical interventions more convenient.

The drug begins to act within a few minutes after use. The effect of pupil dilation lasts about 1-2 hours. It all depends on the concentration of the drug. Paralysis of accommodation lasts for at least half an hour. Its complete completion is possible only 3 hours after the injection.

The drug has a high level of absorption into the systemic circulation. That is, the risk of side effects increases. The substance is excreted after a short period of time. It will take at least 6 hours for the body to fully recover after use.

Features of the interaction of the drug with other drugs

"Tropicamide" (analogues of the drug will be named below) can enhance its effectiveness when used together with "Quinidine", "Procainamide", tricyclic antidepressants, phenothiazines, and antipsychotic substances. Therefore, when prescribing drops, the attending physician must know what additional medications you are taking.

In order to provide paralysis of accommodation, just 1 drop of a 1% solution is enough. However, it should be dripped at least 6 times. The interval between manipulations is about 5-10 minutes. After half an hour - 50 minutes. hardware testing can be carried out.

In order to dilate the pupil, you need to use 1 drop of a more concentrated or 2 drops of a less concentrated medicine. The optimal time for ophthalmoscopy occurs after 10 minutes.

If children under 6 years of age are examined, only a half percent solution should be used. It is also used to eliminate infectious lesions. In this case, you need to drip at least 6 times a day.

It is better to use the substance before bed, as the drug reduces visual acuity and can cause some discomfort. If you use the drug without a system, without following the instructions, an overdose may occur, fraught with very unpleasant side effects.

What consequences may arise?

For some diseases, an ophthalmologist may prescribe the drug Tropicamide - eye drops. Analogues cannot be used independently, as they can only make things worse. However, even this drug can cause unwanted reactions. For example, these:

Behavioral disorders (especially in children), headaches.

Increased intraocular pressure and lacrimation, photophobia.

Problems with visual acuity.

Shortness of breath, erratic heartbeat, circulatory problems, hypotension, hyperemia.

Allergic reactions, dry mouth.

In some cases, confusion, hallucinations, or psychomotor reactions may occur. The drug should not be used intravenously, as this can lead to severe dependence on the drug.

If an overdose of the drug occurs, then you need to use Benzodiazepine. To eliminate hyperemia, it is necessary to constantly moisten the surface of the body with water and use cold compresses. After each use of the drops, be sure to wash your hands with soap.

Please note that in children the side effects are more pronounced. If necessary, after the study, the doctor may give the patient a drug that helps narrow the pupil.

Special instructions for use and analogues

If Tropicamide is not suitable for you, analogues (Russia also produces some medications) can eliminate this problem. Drops should not be used for other purposes. This is an ophthalmic agent for topical use.

Using contact lenses can have negative effects. You can wear them during treatment. However, they need to be put on only half an hour after instillation.

Please note that the presented product can affect concentration and the speed of psychomotor reactions, so you should not drive in the next 2 hours after using the product.

Do not touch the dropper under any circumstances. In this way, you can infect not only the bottle itself, but also the solution inside it. Before starting instillation, be sure to wash your hands with soap. Next, turn the bottle cap until it stops. This will allow you to pierce the top of the IV.

During instillation, try not to touch the mucous membrane of the eye. Next, you need to tilt your head back and pull down your lower eyelid. Place 1 drop of the substance into the resulting bag, close your eyes tightly and press on the tear ducts. In this way you will reduce the absorption of the drug by the body.

After use, wipe off excess liquid with a clean cloth. There is no need to wash or wipe the bottle. Next, simply close the lid tightly.

As for analogues, among them the following can be distinguished:

- "Atropine."

- "Buskopan".

- "Spazmex".

- "Spiriva".

- "Atrovent".

- "Midrum".

- "Midracil".

- "Cycloptic".

Most of these drugs also require a doctor's prescription.

Shelf life and user reviews

It is recommended to store the drug at room temperature. At the same time, try to limit access to the medicine to children as much as possible. Do not expose the bottle to direct sunlight. The dropper cap must be tightly closed. The shelf life of the medicine is 3 years. After opening the bottle, you will have to throw it away within a month.

As for the reviews, they are mostly positive. Patients talk about the high effectiveness of the drug, its speed of action, and low cost (from 70 rubles). The product relaxes the eye muscles well. However, during use, vision is somewhat upset, and a tingling sensation is felt in the eyes. It should be noted that with proper use, the occurrence of adverse reactions was observed in rare cases. Now you know all the information about the drug. Instructions; analogues have been reviewed in detail by us. Be healthy!

1 ml of Tropicamide eye drops may contain 5 or 10 mg of the active substance of the same name.

Additional substances: hydrochloric acid, sodium chloride, benzalkonium chloride, ethylenediaminetetraacetic acid disodium salt, water.

pharmachologic effect

Mydriatic, anticholinergic effect.

What is Tropicamide?

Tropicamide is a drug that suppresses m-cholinergic receptors ciliary muscle and the sphincter muscle of the iris, quickly and for a short time enlarges the pupil and paralyzes the ability to accommodate.

The increase in pupil diameter begins 6-9 minutes after a single instillation of the solution into the conjunctival sac, the maximum effect develops after 17-20 minutes and lasts for 60 minutes when instilling a 0.5% solution and 120 minutes when instilling a 1% solution. After 5 hours the effect disappears completely.

Maximum paralysis of the ability to accommodate after administration of 1% Tropicamide twice with a break of 5 minutes is recorded after approximately 25 minutes and lasts up to half an hour. Restoration of physiological functions occurs in this case after 3 hours.

When the drug is instilled behind the eyelid, the active substance is able to penetrate into the systemic bloodstream to a clinically insignificant extent.

For medicinal purposes, the drug is used for:

• complex therapy of inflammatory eye diseases and postoperative prevention synechia.

For diagnostic purposes, the drug is used for:

• call mydriasis when examining the condition of the fundus and lens;
• call paralysis of accommodation when measuring refraction.

Drops are also used during surgical interventions:

• retinal laser therapy;
• lens surgery;
• vitreous and retinal surgery.

Side effects

• Reactions from nervous activity: behavioral disturbances, psychotic symptoms, headaches.
• Reactions from the vision: deterioration of visual acuity, increased intraocular pressure, photophobia.
• Reactions from the circulatory system: signs of cardiopulmonary failure, tachycardia.
• Other reactions: allergic phenomena, dry mouth.

Instructions for use (Method and dosage)

The drug is used for instillation behind the eyelid; Tropicamide should not be administered intravenously or into the nose.

The dosage regimen when used for medicinal purposes is determined by the doctor individually.

For pupil dilation 1 drop of a 1% solution or 2 drops (with a five-minute interval) of a 0.5% solution of the drug is instilled behind the eyelid. After 10 minutes, ophthalmoscopy is allowed. With low effect strength (high light intensity or use for destruction posterior synechiae) the drug is administered together with Phenylephrine.

For causing paralysis of accommodation(when measuring refraction), 1 drop of 1% of the drug is injected behind the eyelid 6 times with a break of 7-12 minutes. The study is carried out within 30-50 minutes after the last instillation.

In infants and children under 6 years of age, only 0.5% eye drops should be used.

In premature infants, a systemic anticholinergic effect of Tropicamide cannot be ruled out, which increases with each new use. This phenomenon is leveled out without reducing the effectiveness by diluting the drug 0.9% sodium chloride solution in a 1:1 ratio.

When instilling the drug, light pressure should be applied to the lacrimal canals to limit the increased absorption of Tropicamide and prevent the development of a systemic anticholinergic effect.

There are no reports of cases of overdose of the drug when instilled according to the instructions.

Sharing anticholinergic drugs and H1-histamine receptor blockers, tricyclic antidepressants, phenothiazines, Quinidine, Procainamide, benzodiazepines, MAO inhibitors, antipsychotics may mutually enhance their effects.

The paralysis of accommodation created by the drug is enhanced when used in combination with sympathomimetic drugs and is weakened when used together with parasympathomimetic drugs.

When using Tropicamide and nitrites, nitrates, disopyramide, alkalizing agents, glucocorticosteroids, Haloperidol on the background angle-closure glaucoma an increase in intraocular pressure is possible.

On prescription.

Keep away from children. Store in a dark place at room temperature.

Three years. After opening the bottle, store for no longer than 4 weeks.

Before instilling Tropicamide to increase pupil diameter before examining the fundus, the patient should be excluded from angle-closure glaucoma, because if it is present, acute attacks after using the medicine cannot be excluded.

Before using the drug for diagnostic purposes, the patient should be warned about temporary blurred vision and possible photophobia.

It is forbidden to touch the tip of the dropper; failure to comply with this rule causes contamination of the contents of the container with the drug.

Before using Tropicamide, you must remove soft contact lenses. You can place them back half an hour after administration of the drug.

Before using this tool for diagnosis in children, you should notify the accompanying person about the possible temporary deterioration of vision and the appearance of photophobia.

When using this product, you should not drive a vehicle.

Analogues of Tropicamide: Midriacil, Midrum, Midriaticum, Unitropic.

In children under six years of age, only Tropicamide eye drops with a concentration of 0.5% are allowed to be used.

Before using this product for diagnostic purposes in children, you should notify the accompanying person about the possible temporary deterioration of vision and the development of photophobia.

The use of the drug in infants and young children can cause neurological disorders.

During pregnancy, it is possible to use the product only with the permission of the attending physician and if indicated.

During lactation, the product must be used with extreme caution.

Reviews of Tropicamide indicate 100% effectiveness of the drug when used both for diagnostic purposes and for the treatment of ophthalmological pathologies. Reviews of eye drops in children, pregnant and lactating mothers do not report the development of additional side effects or their occurrence for more than an hour compared to other groups of patients.

There are quite often articles on the Internet with the titles “Tropicamide for addicts”, or “Why do drug addicts use Tropicamide?” This drug is often used as an intravenous drug, which entails persistent addiction and serious consequences for the health and life of those who administer it.

Photos of the effects of Tropicamide intravenously

Tropicamide price, where to buy

The price of Tropicamide eye drops 0.5% 10 ml in Russia is 63-69 rubles. Buying this form of release in Moscow will cost approximately the same amount - prices do not differ from the Russian average.

In Ukraine, the average price of Tropicamide 0.5% 5 ml ranges from 23-26 hryvnia.

Tropicamide 1% 5ml No. 2 eye drops

Tropicamide 1% 10ml eye drops

Tropicamide eye drops 0.5% polyethylene 5mlFarmak (Ukraine, Kyiv)

Tropicamide h/c 0.5% p/e 5ml

Tropicamide 1%/5 ml No. 2 eye drops. Warsaw Pharmaceutical Plant Polfa JSC (Poland)

Tropicamide 0.5%/5 ml No. 2 eye drops. Warsaw Pharmaceutical Plant Polfa JSC (Poland)

Tropicamide 0.5%/10 ml eye drops. Rompharm Company S.R.L. (Romania)

Tropicamide 1%/10 ml eye drops. Rompharm Company S.R.L. (Romania)

is a solution used as eye drops. According to its pharmacological properties, Tropicamide belongs to the class

M-anticholinergics, which act on the receptors of the sphincter of the iris and the ciliary muscle of the eye, which changes the width of the pupil. As a result of the action on the receptor structures of the sphincter of the iris and the ciliary muscle of the eye, a short-term strong dilation of the pupil (mydriasis) occurs with simultaneous

paralysis

accommodation. Paralysis of accommodation is a condition in which the eye muscles are unable to regulate the width of the pupil depending on the amount of light flux. That is, Tropicamide, on the one hand, dilates the pupil, and on the other hand, prevents its narrowing.

This effect of Tropicamide is used in practical ophthalmology, when the doctor needs to examine the fundus of the eye, determine refraction using skiascopy, or for the effective treatment of inflammatory phenomena and adhesions in the eyes. Tropicamide is also used to prepare for surgical and laser operations on the eyes.

To date, Tropicamide is available in only one dosage form - eye drops. Tropicamide is a colorless and transparent solution, packaged in a plastic bottle with a 5 ml dropper dispenser. This medicine is produced by the pharmaceutical corporation "WARSAW PHARMACEUTICAL WORK POLFA, S.A." at factories located in Poland.

Tropicamide eye drops contain as an active component a chemical substance with the same name as the finished drug - tropicamide. Today, the drug is available in two dosage options - with a concentration of the active component of 0.5% and 1%. A 0.5% solution of Tropicamide contains 5 mg of active substance per 1 ml. And in a 1% solution the content of the active substance is 10 mg per 1 ml.

Tropicamide 0.5% and Tropicamide 1% are available in identical bottles with a 5 ml dropper dispenser. Sometimes, in order to designate a drug with a certain dosage, the terms “Tropicamide 0.5” and “Tropicamide 1” are used, where the number corresponds to the concentration of the active substance.

The auxiliary components in Tropicamide 0.5% and 1% are the same and are contained in equal quantities. So, Tropicamide eye drops contain the following substances as auxiliary components:

• sodium chloride (table salt);
• disodium ethylenediaminetetraacetic acid (sodium EDTA);
• benzalkonium chloride;
• hydrochloric acid;
• specially purified and deionized water.

usually written out as follows:

Rp.: Tropicamide 0.5% - 5 ml

D.S. 2 drops in each eye. An interval of 5 minutes should be maintained between drops.

Prescription for Tropicamide 1% as follows:

Rp.: Tropicamide 1% - 5 ml

D.S. 1 drop in each eye.

In the recipe, after the designation “Rp.” The name of the drug in Latin is indicated, as well as the concentration of the solution and the volume of the bottle with eye drops. In the second line of the recipe after the designation “D. S." the dosage regimen and instructions for use of the drug are indicated.

Tropicamide is a drug from the group of M-anticholinergic drugs. This means that it blocks M-cholinergic receptors located in the muscles and blood vessels of almost all organs and tissues of the human body. The letter “M” in the name of the receptors stands for an abbreviation for the word “muscarine”. Muscarine is the name of a substance that is the main mediator and intermediary for the inclusion of these receptor structures. M-anticholinergic - means that the substance has the ability to block the functioning of the receptor structure due to the inactivation of muscarine, which causes certain effects.

If an M-anticholinergic agent is administered intravenously, the effects of blockade of muscarinic receptors will manifest themselves in the form of changes in the functioning of all organs and systems. And if an M-anticholinergic agent is used topically, like Tropicamide as eye drops, then the drug causes effects only in the area that was exposed to the drug.

Tropicamide acts on M-cholinergic receptors located in the iris and ciliary muscle of the eye. As a result of blocking the receptors, muscle relaxation occurs, which lasts a short time. Relaxation of the iris sphincter and ciliary muscle leads to maximum pupil dilation and paralysis accommodation. The phenomenon of accommodation itself lies in the ability to adjust the width of the pupil depending on the intensity of light. Palsy of accommodation occurs when relaxed muscles are unable to constrict the pupil when an intense beam of light enters the eye. That is, Tropicamide dilates the pupil due to maximum muscle relaxation and keeps it in this state. Keeping the pupil dilated is achieved by maintaining the muscles in a relaxed state.

Pupil dilation ( mydriasis) reaches a maximum 15 - 20 minutes after instillation of Tropicamide solution into the eye. The onset of pupil dilation is observed 5 to 10 minutes after instillation of the solution. Mydriasis persists for 1 hour after instillation of a 0.5% solution into the eye, and for 2 hours after application of a 1% Tropicamide solution. Normal pupil width is restored 5 to 6 hours after instilling the drug into the eyes.

Paralysis of accommodation develops as a result of several repeated instillations of Tropicamide solution into the eyes. The maximum severity of paralysis of accommodation is recorded after double instillation of a 1% solution after 15 minutes, counting from the last injection of the drug into the eye. Paralysis of accommodation persists for half an hour after its development. Complete restoration of the pupil's ability to accommodate occurs 3 hours after instillation of Tropicamide.

Tropicamide has a shorter duration of action on the eye than atropine. In addition, Tropicamide drops do not have as strong an effect on ophthalmotonus as atropine. Despite its milder effect compared to atropine, Tropicamide can lead to an increase in intraocular pressure. This factor must be kept in mind when a person suffers from angle-closure glaucoma.

Tropicamide eye drops are used for diagnostic procedures, to prepare the eyes for surgical interventions, and also as a therapeutic agent. Indications for the use of Tropicamide eye drops for diagnostic, preparatory and therapeutic purposes are shown in the table:

Tropicamide drops should be instilled into the lower part of the conjunctival sac. You can instill the solution into your eyes using a pipette or a special dropper with which the bottle is equipped. If a bottle dropper is used, you should avoid touching the tip as this may contaminate it and introduce germs into your eyes. Before instilling Tropicamide, you must remove contact lenses. You can put on contact lenses again after half an hour after instilling the drug.

After instillation, Tropicamide causes visual disturbances and photophobia, which disappear on their own after the drug wears off. When the medicine is injected into the eyes, it is necessary to pinch the tear ducts with your finger for 2 - 3 minutes to prevent the solution from entering the nose, from where it is almost completely absorbed into the bloodstream. Tropicamide entering the bloodstream by absorption through the nasal mucosa leads to the development of systemic effects of M-anticholinergics, which manifest themselves in:

• difficulty urinating;
• dilation of blood vessels with a drop in pressure;
• inhibition of sweating and secretion production by all mucous membranes;
• dry mouth, etc.

In order to maximize pupil dilation, it is necessary to drop a 1% or 0.5% solution into the eyes. In this case, one drop of a 1% solution or two drops of a 0.5% solution is sufficient. If a 0.5% solution is used, then one drop is first injected into the eye, and the second only after five minutes. After 10 minutes, the pupil dilates and allows for diagnostic manipulations. If pupil dilation is not sufficient, then Tropicamide can be used simultaneously with phenylephrine.

In order to develop paralysis of accommodation, to conduct a refractive study, it is necessary to inject one drop of a 1% Tropicamide solution into the conjunctival sac of the eye six times, with an interval of 6 to 12 minutes between them. A refractive examination can be performed between 25 and 50 minutes after the last (sixth) drop of solution is administered to the eyes.

Tropicamide can be used in children from birth. However, in children under 6 years of age, only 0.5% concentration of Tropicamide can be used. Premature infants have an increased risk of developing systemic effects of Tropicamide due to the drug entering the nose and subsequent absorption into the blood through the mucous membrane. Tropicamide enters the nose through the nasolacrimal duct. But through the nasal mucosa, almost all the amount of the drug that gets on it is absorbed into the blood. As a result of entry into the blood, Tropicamide has systemic effects such as dry mouth, persistent dilation of the pupils, difficulty urinating, vasodilatation with a drop in pressure, intestinal hypotension, tachycardia, nervous agitation, hallucinations and increased body temperature.

With repeated use of Tropicamide in premature infants, the risk of developing systemic effects of the drug increases. To reduce this risk and prevent systemic effects of the drug in premature infants, it is necessary to dilute the drug with saline in a 1:1 ratio. And it is necessary to use exactly this 0.5% solution of Tropicamide, diluted in half, into the eyes of premature babies.

For the treatment of inflammatory eye diseases (for example, keratitis, iridocyclitis, uveitis), Tropicamide is also used as part of complex therapy. Typically, the drug is prescribed one drop of a 1% solution in each eye daily in the evening (before bedtime), for 2 to 4 weeks. The minimum period of therapy with Tropicamide is 2 weeks, but if the disease has not completely resolved after this period, the course of treatment can be extended to 4 weeks.

Interaction with other drugs. When used simultaneously with histamine blockers (Zyrtec, Erius, Suprastin, Diazolin, Fenistil, Claritin, etc.), phenothiazines, antidepressants, Procainamide, Quinidine, benzodiazepines and antipsychotics, the effects of Tropicamide and the listed drugs are mutually enhanced.

The combined use of Tropicamide and nitrites (Nitroglycerin, etc.), Disopyramide, glucocorticosteroids (Dexamethasone, etc.) and Haloperidol leads to a strong increase in intraocular pressure.

Overdose When applied topically, Tropicamide was never detected. If the drug enters the bloodstream (for example, by absorption through the mucous membranes of the nose), the following may develop:

• dry skin and mucous membranes;
• tachycardia;
• nervous excitement;
• convulsions;
• at high dosages - coma and paralysis of the respiratory center with a fatal outcome.

To treat systemic manifestations of Tropicamide, gastric lavage should be performed, and then activated charcoal should be given to the person. It is also recommended to administer 1–2 mg of physostigmine intravenously. Physostigmine can be administered every hour. If convulsions develop, they must be stopped by intravenous administration of 10–20 mg of diazepam. When a fever develops, the person should be cooled using physical methods - cold water, hot water bottles with ice, etc. The condition of a person who has taken Tropicamide orally should be monitored and the necessary symptomatic medications should be administered until his condition is completely normalized.

In children under 6 years of age, only 0.5% Tropicamide drops can be used. To minimize the risk of developing systemic effects of the drug, it should be diluted in a 1:1 ratio with saline solution. Thus, immediately before use, you should prepare a 0.25% solution from a 0.5% solution, and use it for instillation into the eyes of children. To dilute Tropicamide, use a sterile saline solution purchased from a pharmacy.

To treat inflammatory processes in the eyes, Tropicamide is best taken in the evening, before going to bed. Typically, one drop of a 0.25% solution is instilled into each eye. Instillation is carried out daily for 2 - 4 weeks.

When using Tropicamide for the purpose of performing diagnostic procedures, you must be aware that the drug will lead to temporary visual impairment and photophobia. These phenomena will go away on their own after the drug wears off, without any additional treatment.

Tropicamide should be used very carefully in infants, since at this age the drug can lead to the development of disorders in the central nervous system.

Tropicamide is contraindicated for eye drops only if a person has the following conditions:

1. Closed angle and mixed primary

glaucoma

2. Increased intraocular pressure.

3. Sensitivity,

allergy

or intolerance to Tropicamide components.

Tropicamide may cause local and systemic side effects. Local concerns exclusively the place of application of the drug and manifest themselves in various ways.

symptoms

Concerning the eye and vision. And systemic side effects appear when Tropicamide enters the bloodstream, for example, when the solution is absorbed through the mucous membranes of the nose, where it flows through the nasolacrimal duct if it is not applied with the fingers. Systemic side effects most often develop in young children and the elderly.

All local and systemic side effects of Tropicamide are reflected in the table:

Today, drugs synonymous with Tropicamide include the following drugs:

• Eye drops – Mydriacyl;
• Eye drops – Midriaticum-Shtuln PU;
• Eye drops – Midrum;
• Eye drops – Tropicamite;
• Eye drops – Unitropic.

The following drugs are analogues of Tropicamide eye drops on the domestic pharmaceutical market:

• Drops and ointment for eyes – Atropine;
• Atropine sulfate eye films;
• Eye drops – Cyclomed;
• Eye drops – Cycloptic.

Often, adults and parents who have undergone a fundus examination procedure using Tropicamide speak positively about the drug and reassure those who ask questions about the action of the drops on various forums and blogs. People note that the drug briefly impairs vision and also causes only a slight tingling sensation in the eyes, which is easily tolerated even by children. Moreover, the majority of parents indicate that children do not even cry after instilling Tropicamide into the eyes. The overall public opinion about the drops agrees that the drug is not at all scary, and it can be safely used for both children and adults who need to dilate the pupil for some purpose.

The second and very large part of the reviews about Tropicamide consists of statements from drug addicts and their relatives. Drug addicts use Tropicamide in the form of nasal drops, intravenous injections, or add it to heroin to enhance the effect of the latter. Drug addicts use Tropicamide internally precisely for the purpose of obtaining its systemic effects, such as nervous excitement, hallucinations, etc. Some respond well to it because they like the effect, while other drug addicts, on the contrary, are dissatisfied with the effect of Tropicamide. According to narcologists, the drug causes very rapid addiction and severe withdrawal syndrome (withdrawal), which lasts at least a month.

The cost of Tropicamide drops is determined by the price of the wholesale batch, which is purchased abroad and imported to Russia. In addition, the cost of the drug is determined by the amount of customs duties, transportation and storage costs. However, since Tropicamide is produced by only one pharmaceutical company, there is no difference between drugs sold at different prices.

Today, in Russian pharmacy chains, the cost of a 0.5% solution ranges from 60 to 76 rubles, and a 1% solution – 110 – 121 rubles.

You can purchase the drug at almost any pharmacy. Due to the tightening of the circulation of drugs that affect the central nervous system, today Tropicamide is sold exclusively by prescription. This is due to the creation of obstacles for drug addicts who buy Tropicamide and administer it intravenously instead of injecting

narcotic drugs

When purchasing Tropicamide, you should pay attention to the expiration date of the medicine, as well as the integrity of the packaging. The shelf life of 0.5% and 1% Tropicamide solution is the same and is three years from the date of manufacture of the drug. Eye drops should be stored in a dark place, at an air temperature between 15 and 25oC. Violation of storage rules leads to loss of therapeutic effect or its significant weakening. If the Tropicamide package is dented or opened, the drug should not be purchased.

In April 2013, the Ministry of Health issued a decree according to which Tropicamide, from June 25 of this year, moves into the category

medicines

Subject to subject-quantitative accounting. This means that patients will only be able to receive eye drops based on a special prescription, which must be written by an ophthalmologist.

This measure was introduced due to the fact that the sale of Tropicamide according to prescription form No. 107-1/u does not prevent the acquisition of the drug by drug addicts who use it to enhance the effects of injecting drugs or as an independent means to help obtain a drug-like effect. That is why, according to the new order of the Russian Ministry of Health, Tropicamide will be dispensed from pharmacies according to prescriptions of form No. 148-1/u-88, having a series and number. These prescriptions will have to be stored in the archives of pharmacies for three years.

This order is called “On approval of the list of medicines for medical use, subject to subject-quantitative accounting” dated 04/05/2013. Thus, Tropicamide is placed in the same group with potent, narcotic and poisonous drugs. In addition to the order, an explanatory note was issued to the draft order of the Ministry of Health of Russia “On approval of the list of medicines for medical use, subject to subject-quantitative accounting”, and a new “List of medicines for medical use, subject to subject-quantitative accounting”, which includes Tropicamide.

Midriacil is an ophthalmic drug that contains tropicamide as an active ingredient. Moreover, as in the drug Tropicamide, Midriacil contains 5 mg or 10 mg of the active substance per 1 ml. That is, Midriacil is also available in two concentrations - 0.5% and 1% solution. However, unlike Tropicamide, Midriacil drops are available in 15 ml bottles, which are equipped with a special Drop-Tayner dispenser. In fact, Midriacil is a drug synonymous with Tropicamide, which is manufactured by another pharmaceutical concern.

When using Midriacil to dilate the pupil, for example, when examining the fundus, it has a weaker effect compared to Tropicamide. Therefore, if Mydriacyl was unable to dilate the pupil to the required size, then you should resort to Tropicamide. Due to its weaker effect, Midriacil is a better option for use in young children compared to Tropicamide.

The human eye is an amazing system. And eye diseases entail severe discomfort. In some cases, during medical interventions or for therapeutic purposes, it is necessary to use pupil dilators, such as Tropicamide. Analogues of this drug must contain the same active substance and work accordingly.

The eyes of living creatures are a complex system consisting of many components, one of which is the pupil. It is a hole designed to allow light rays to enter the eye, where the visible image is focused, converted into nerve-electric impulses and sent to the brain for processing and analysis. Depending on the intensity of the light flux directed into the eyes, the pupils may narrow or dilate. This ability is called accommodation - the adaptation of an organ to external conditions. The “light gate” operates under the control of several components: the autonomic nervous system causes the dilator and sphincter of the pupil to act, allowing light to pass through, and then other components of the visual system begin to work. Medicines such as Tropicamide, its analogues, work to dilate the pupil, regardless of the amount of light entering the organ of vision.

In ophthalmology, special components of medications are used that affect the functioning of the visual system, causing the pupil to dilate. One of these drugs is Tropicamide. Reviews about it are in the vast majority of cases positive; people note the effectiveness of the drug in cases of justified use. Thus, some of those who have used this product even note an improvement in vision, since the drops relieve fatigue well after prolonged visual strain, for example, when working with small objects. Some patients who suffered from conjunctivitis are grateful to Tropicamide drops that they helped get rid of purulent discharge. Both women and men note that the drops cope well with eye redness caused by overwork. The product is available in the form of drops, in which one active ingredient is tropicamide. Its amount can be 5 mg or 10 mg in 1 ml of liquid of the drug, which corresponds to 0.5% and 1% solution.

If it is necessary to cause paralysis of accommodation of the iris and pupil of the eye, ophthalmologists prescribe the drug "Tropicamide". The composition of this product is as follows:

• tropicamide,
• benzalkonium chloride,
• hydrochloric acid,
• sodium chloride,
• ethylenediaminetetraacetic acid disodium salt,
• water.

An active remedy for forced dilation of the pupil of the eye - Tropicamide drops. The instructions for use of this medicine indicate what substances it contains. But how does it work to cause paralysis of accommodation of the sphincter and ciliary muscle of the eye, but not harm vision?

The substance tropicamide is an M-anticholinergic blocker, which stops the functioning of the iris receptors that react to light. This action of the substance causes a temporary dilation of the pupil, which is called mydriasis.

The drug "Tropicamide" (eye drops) has a special purpose: it interferes with the ability of the eye apparatus to adapt to the amount of light entering the retina through the pupil, causing paralysis of the sphincter of the iris, which dilates and contracts the pupil. Indications for the use of this drug are:

• inflammatory eye diseases;
• postoperative condition (prevention of the formation of adhesions - synechiae of the iris);
• during a diagnostic examination of the lens or fundus of the eye;
• when measuring the refraction of the eye (the process of refraction of light rays perceived by the eye).

This drug is used during surgery on the lens, retina or vitreous body of the eye.

Being an organic M-anticholinergic blocker, Tropicamide (eye drops) is used to paralyze the pupil - its forced dilation for a short time. The drug has a local effect, not being systemic, although, quickly absorbed into the blood, it acquires the properties of a systemic drug. Its use is contraindicated in some cases. This medicine should strictly not be used for angle-closure and primary mixed glaucoma. These are two separate types from a fairly large number of eye diseases caused by an increase in intraocular pressure above the permissible level. With a form of glaucoma such as angle-closure, the outflow of intraocular fluid can be blocked by pupil dilation under the influence of Tropicamide.

The drug is available in the form of drops in a bottle with a dropper-dropper. This simplifies dosing of the drug to avoid overdose. Only the attending physician decides in what dose and regimen to use this medicine. To dilate the pupil for ophthalmoscopy, instill 1 drop of a 1% solution or 2 drops of a 0.5% solution with an interval of 5 minutes. If the effect of mydriasis is insufficient, phenylephrine is additionally used. To measure refraction, 1 drop of a 1% solution is administered with a break of 7-12 minutes. The procedure should be carried out within a maximum of 50 minutes after the last instillation. The complete cessation of the effect of the drug occurs within 5 hours. Children are advised to use a 0.5% solution of the drug. Treatment with Tropicamine instead of Atropine is prescribed by a doctor; it is carried out by instilling 1-2 drops of the drug into each eye 6 times a day. When administering the drug, one should be aware of its absorption into the bloodstream and possible systemic effects. To reduce this effect, when instilling the medicine, you should press on the corner of the lower eyelid to narrow the tear duct through which the medicine enters the body.

By dilating the pupil, the drug "Tropicamide" can cause the following side effects:

• allergic reactions;
• dysuria;
• hyperthermia;
• hypotension;
• headache;
• accommodation paresis;
• increased intraocular pressure;
• psychotic disorders;
• dry mouth;
• tachycardia;
• photophobia - photophobia.

Any side effects caused by the use of the drug "Tropicamide" require symptomatic treatment under the supervision of a doctor.

"Tropicamide" - eye drops intended for instillation behind the eyelid in a certain amount according to a certain scheme. It is quite difficult to overdose on a drug unless you do it intentionally. But if an overdose occurs, then symptomatic treatment is possible. It is carried out with Physostigmine, a drug made from Calabar beans. This medicine is a parasympathomimetic alkaloid that constricts the pupil and reduces intraocular pressure. This drug is used as an antidote. It is also possible to use symptomatic treatment with benzodiazepines - psychoactive drugs with a hypnotic and sedative effect, beta-blockers to normalize cardiac activity and cold lotions for hyperthermia.

The drug “Tropicamide” is actively used in medical practice. Its analogues contain the same active substance and are used for the same indications. There are many such drugs in the pharmacy chain, but only the attending physician can prescribe this or that drug for use, taking into account the medical history and the need for a particular drug. The absolute analogue of “Tropikamin” is “Mydriatsil”. The difference between these two medicinal products is only in price - Tropicamil is cheaper than its analogue Midriacil. But in the clinic of eye diseases, ophthalmologists also use other substances that have a similar effect to tropicamil. For example, phenylephrine. This substance also causes mydriasis and stimulates the outflow of intraocular fluid.

Sometimes pharmacists hear the question: “Irifrin” or “Tropicamide” - which is better?” It is impossible to give a definite answer to this, since drugs for use are prescribed by the attending physician, taking into account all the specific characteristics of the body and the purpose of using the drug. Although these two drugs have somewhat similar effects, they have different purposes. The doctor uses this as a starting point when recommending the use of a particular drug.

The drug “Tropicamide”, used for the treatment of ophthalmic diseases, the instructions for use of which contains all the information necessary for the patient and the doctor, is a local agent. But one should take into account its compatibility with other substances that the patient takes, since the substance is absorbed into the blood and becomes systemic. Adrenergic agonists enhance the functionality of tropicamide, but M-cholinergic stimulants, on the contrary, weaken it. Some antidepressants (tricyclics), the antiviral drug amantadine, the antiarrhythmic drug quinidine and antihistamines can cause systemic side effects.

The drug "Tropicamide" itself and its analogues require some special measures in use. The drug should not be used without removing contact lenses. They must be removed before applying the product, and installed back half an hour after the procedure. After instilling the medication, it is necessary to press on the lacrimal sac to reduce the penetration of the drug into the systemic bloodstream. During the period of using this drug, you must refrain from driving vehicles and performing work that requires extreme concentration. Any use of Topikamide requires a mandatory preliminary examination to detect glaucoma. Under no circumstances should the drug “Tropicamide” be used for other purposes; this leads to disastrous consequences for health and life.

Tropicamide eye drops are a special solution that is used as eye drops. Its main property is considered to be a significant ability to dilate the pupils while simultaneously preventing its narrowing.

Tropicamide eye drops dilate pupils

A similar property may be required during fundus examination. Pupil dilation is also necessary for the treatment of adhesive phenomena.

The main form of release of tropicamide is drops. They are made in the form of a colorless liquid, which is packaged in a special plastic bottle. The bottle also has a special dispenser that simplifies the instillation process. The active ingredient in the composition is tropicamide. Basically, the drug can have two types of dosage. The first option includes the presence of 5 mg of the active ingredient, and in the second option the amount of the active ingredient will be 10 mg.

In addition to the main substance, other active ingredients can also be found in the drops:

• Sodium chloride.
• Sodium EDTA.
• Hydrochloric acid.
• Benzalkonium chloride.
• Purified water.

These are additional components that contain Tropicamide eye drops.

At the moment, tropicamide is included in the group of M-anticholinergic drugs. Thanks to this action, it is possible to block the eye muscles for a certain period. They will begin to expand, and accordingly the eye pupil will also expand. The pupil of the eye can be kept relaxed while using tropicamide.

It is important to know! Relaxation of the pupil occurs after about 5-10 minutes. The maximum effect can be seen after 20 minutes. This condition can last for an hour.

Many experts can also compare the effect of tropicamide with Atropine eye drops. The only peculiarity is that after using tropicamide, an increase in eye pressure can be avoided.

The instructions for tropicamide eye drops state that they should be used for:

• Carrying out diagnostics.
• Preparations for the operation.
• Treatments.

From a diagnostic point of view, these eye drops can be intended for:

• Checking the eye lens.
• Fundus examinations.
• Analysis of eye refraction.

For surgical purposes, the use of tropicamide may be required for:

• Cataract extractions.
• Laser therapy of the retina.
• Operations on the vitreous body.

Tropicamide solution 1%

Treatment with eye drops also involves:

• Carrying out anti-inflammatory therapy.
• Prevention of synechiae after surgical interventions.

Now you know when to use these drops. During use, it is imperative to consult a specialist.

Tropicamide eye drops are contraindicated for:

1. Angle-closure or mixed glaucoma.
2. Hypersensitivity to the drug.
3. Intraocular pressure.
4. Intolerance to components.

During use, you must also remember that using this type of drops is not recommended for pregnant women.

While using these drops, you may experience local or systemic side effects. Local character can be manifested by the following symptoms:

• Photophobia.
• Burning in the eyes.
• Violation of accommodation.
• Angle-closure glaucoma.
• Increased intraocular pressure.

Systemic effects may occur when drops enter the bloodstream. The most common symptoms include:

• Suppression of sweating.
• Dry mouth.
• Headache.
• Increase in temperature.
• Nervous excitement.

Most often, these factors can occur in older people. To avoid such problems, consult with specialists.

The instructions for using Tropicamide eye drops state that the traditional method of use is instillation into the conjunctivitis sac. A special dropper located on the bottle will help you perform this procedure. This solution must be administered one drop into each eye before going to bed. The duration of treatment is up to 4 weeks.

Eye drops are best used before bedtime

When using the dropper, which is located on the bottle, it is better not to touch it. Otherwise, you may get an infection. If you use contact lenses, then remember that they must be removed. You can put on lenses only 30 minutes after administering the drops.

To ensure maximum pupil dilation, a drop of a 1% solution or 2 drops of a 0.5% solution is enough. In the second case, the interval before use should be approximately 5 minutes. In just 10 minutes you will be able to see the first results.

Paralysis of accommodation may need to develop for refractive testing. To do this, it is necessary to instill 1 drop into the conjunctivitis sac 6 times every 10 minutes.

While using these drops, it is necessary to clamp the tear ducts. Thanks to this, you can prevent droplets from entering the nasopharynx. Otherwise, the drops may be absorbed into the bloodstream. Photophobia and visual disturbances will go away after this drug wears off.

Tropicamide drops

For the treatment of children under 6 years of age, it may be necessary to use a 0.5% solution. Also, when using these drops, they must be diluted with saline. solution. Only in this case can the drops be used for children.

If Tropicamide is used with antipsychotics or antidepressants, then an enhancing effect can be noticed. It is not recommended to combine these drugs, as intraocular pressure may increase significantly.

Once purchased, these drops will need to be stored in their original packaging. The storage location must be protected from sunlight. In Russia, the cost of the drug will be from 100 to 140 rubles. If you want to purchase drops in Ukraine, then remember that their cost will be about 50 hryvnia.

If you haven’t found the original drops, then remember that you can use the following analogues:

1. Cyclomed.
2. Atropine.
3. Cycloptic.
4. Atropine sulfate eye films.

These are the main drugs that have a similar effect. We hope that this information will be useful and interesting.

Most people are accustomed to eye drops being used to treat diseases. However, there are drugs whose main purpose is to prepare patients for diagnostic procedures and studies. Tropicamide is one such remedy. This is exactly what we will talk about in this review.

Composition and effects on the body

The active component of the drug is a substance of the same name, tropicamide. The product also contains auxiliary ingredients such as:

• sodium chloride (better known as table salt);
• EDTA-sodium;
• hydrochloric water;
• benzalkonium chloride;
• distilled water.

The principle of action of Tropicamide is as follows. Vessels, tissues, and organs contain so-called M-cholinergic receptors. These receptors carry a number of physiological functions, from muscle contraction to increased secretion in the glands. However, in nature there is a class of substances that can block the functioning of M-cholinergic receptors. Such substances are called M-anticholinergics. The hero of our article belongs to them.

Tropicamide eye drops block cholinergic receptors, which are contained in the iris of the eye. This causes the eye muscles to relax for a while. Along with relaxation, the so-called mydriasis occurs - dilation of the pupil. At the same time, the eye muscles responsible for its narrowing are simultaneously blocked, which in medicine is usually called paralysis of accommodation. Thus, eye drops maintain the pupil in a dilated state.

The drug is used to dilate the pupil during diagnosis and treatment.

Does Tropicamide help with myopia? Yes. The medicine relieves spasm of accommodation, which helps to partially improve vision.

Manufacturer and release form

The drug is produced by the Romanian company Rompharm.

Tropicamide is available only in the form of eye drops. The medicine is a colorless transparent liquid. The medication is packaged in polyethylene dropper bottles with a capacity of 5 ml and sold in cardboard boxes with instructions for use.

Storage conditions: temperature within 15-25 degrees Celsius; keep in a dark place, protected from light. Shelf life - 3 years, after opening - 4 weeks.

The average cost of Tropicamide is 100 rubles. To purchase the drug, you must present a prescription from a doctor: in large dosages, Tropicamide causes a narcotic effect.

Indications

Tropicamide is used for diagnosis and before certain operations. Indications for use may include:

• lens surgery;
• surgery on the retina and vitreous body;
• retinal laser therapy;
• the need for paralysis of accommodation to study refraction (anatomical feature of the eye apparatus that causes myopia or farsightedness);
• the need for mydriasis during examination of the fundus and lens.

Tropicamide is not widely used in the field of therapy. But still, it is used to treat inflammatory eye diseases.

The medicine is prescribed to patients after surgery to prevent adhesions, also known as synechiae (when the iris sticks to the cornea or lens).

Mode of application

Drops should be instilled into the lower part of the conjunctival sac(the space between the eyelids and the eyeball). The dosage depends on the purpose:

• For diagnostic procedures, 1 drop for a 1% solution or 2 drops for a 0.5% solution will be sufficient. An examination can be carried out 10 minutes after instillation.
• To determine refraction, you need to drip the medicine 6 times, 1 drop each. There should be an interval of 6-12 minutes between procedures. Half an hour to an hour after the onset of paralysis of accommodation, you can begin the examination.
• For therapeutic treatment, the dosage is prescribed by the attending physician.

A pipette or a special dropper that comes with the drug will help you control the dose.

When buying medicine, pay attention to the dosage!

Can Tropicamide be used for children? Yes, but adhering to certain rules. When treating children under 6 years of age, only 0.5% drops are used, which are diluted with saline to a concentration of 0.25%. The resulting solution is perfect for a child and will not cause side effects.

Important! If you use Tropicamide on a newborn, you need to be especially careful. The drug may affect the central nervous system.

Tropicamide during pregnancy

Before you start using it for pregnant women, you need to consult a doctor to assess how necessary the drug is, and whether it can be replaced with analogues. The use of Tropicamide while breastfeeding is not recommended.

Contraindications

Tropicamide cannot be used by patients who suffer from glaucoma or are prone to it(for example, they have too narrow an angle of the anterior chamber of the eye). Otherwise, it can only worsen the patient's condition. Tropicamide should not be prescribed to those who have increased sensitivity (sensitivity) to the active substance.

Side effects

If you ignore contraindications or overdose, side effects may follow. The most common ones are photophobia, temporary vision problems, increased intraocular pressure.

Side effects can affect not only the organs of vision. The drug can also negatively affect the central nervous system. Possible headaches, changes in behavior, manifestation of psychosomatic symptoms (alertness, aggressiveness, emotionality, etc.). This is especially true for teenagers and children with unstable mental health.

Side effects can also affect the cardiovascular system and manifest themselves in the form of tachycardia, respiratory and circulatory failure (shortness of breath, dizziness, etc.).

When using Tropicamide, allergies, dry mouth, and vomiting are possible.

Reviews

Reviews will help you get useful information about the drug.

Igor from Tver writes:

“I’ve had problems with my eyes since school. I recently went to work where good eyesight is required. On the recommendation of the attending physician, Tropicamide began to drip. It feels like it has gotten better. I have been using the drug for a couple of weeks now. The product is quite cheap. I haven’t noticed any significant disadvantages yet.”

Victoria, mother of 3-year-old Dima from Minvod, shares:

“When the doctor prescribed Tropicamide drops for my child due to eye spasms, I was afraid of the list of side effects and became wary. The doctor calmed me down and told me how to use the medicine. I started giving the drug to my baby. The first results were not long in coming. The drops relax the eye muscles, which has a positive effect on the child’s vision. The only drawback is that the drug causes a burning sensation, so the baby may be capricious.”

Dr. Nikolai Alekseevich Krasnov, an ophthalmologist of the highest category from Tolyatti, recommends:

“From personal experience I can say that Tropicamide is indispensable in preparation for diagnostic procedures. The medicine, due to its mydriatic effect, is quite effective. The therapeutic properties of the drug are another plus. “I have repeatedly prescribed drops to treat eye inflammation.”

Analogs

Analogs of Tropicamide - drugs that also block M-cholinergic receptors and dilate the pupil can be divided into two groups. The first is products that are similar in composition. These include:

• Mydriacyl. The medicine is available in the form of eye drops. The average cost of Midriacil is 200 rubles per bottle with a capacity of 15 ml.
• Midrimax. They contain not only tropicamide, but also phenylephrine. The average price is 270 rubles per 5 ml bottle.

The second group includes drugs similar to Tropicamide in action, but with a different active ingredient. This group includes:

• Irifrin. The active substance is phenylephrine hydrochloride. The drug increases the amount of norepinephrine. Possessing alpha-adrenergic activity, it is capable of dilating the pupil when used locally. The expansion process can take anywhere from 10 minutes to an hour. The effect lasts up to 6 hours. In most pharmacies you can buy the drug for 550 rubles (5 ml bottle). Among the advantages of the drops one can note their high efficiency. Disadvantage: possible side effects.

Analogue of Tropicamide - Irifrin.

• . Extremely powerful analogue. The effect of pupil dilation lasts 7-10 days. At the same time, the main disadvantage of the drug is a significant number of contraindications and side effects. Because of this disadvantage, doctors today prescribe Atropine less and less. It is prohibited to use the drug on your own. Treatment should be carried out under the supervision of a specialist. Price - 50 rubles for 5 ml.
• . Works in a more gentle mode. After using the drops there is practically nocause side effects. The active ingredient is cyclopentalate, which also belongs to M-anticholinergic agents. The cost of the medicine is 575 rubles (5 ml bottle).
• Mezaton. The active ingredient is phenylephrine. The cost of the product is about 50 rubles for 10 ampoules.

Conclusion

Tropicamide is a mydriatic that is successfully used in ophthalmology. It does not have widespread therapeutic use, but is often useful in various diagnostic procedures and studies. The product can be used to treat children. Pregnant women are not recommended to use the drops.

Alexander Rekhlitsky