Sanorin. Instructions for the drug, use, indications, contraindications, side effects. Drops, spray and emulsion Sanorin: indications and features of use Sanorin vasoconstrictor drops
P N011463/03Trade name of the drug: Sanorin with eucalyptus oil.
International nonproprietary name of the drug: Naphazoline.
Dosage form:
nasal drops.Compound:
10 ml of the drug containActive substance
Naphazoline nitrate 0.010 g.
Excipients
Ethylenediamine, boric acid, cetyl alcohol, methyl parahydroxybenzoate (methylparaben) (0.010 g), eucalyptus leaf oil (eucalyptus oil), polysorbate 80, cholesterol, liquid paraffin (vaseline oil), purified water.
Description
White homogeneous emulsion.
Pharmacotherapeutic group
Anticongestant - vasoconstrictor (alpha-adrenergic agonist).
ATX code: K01AA08.
Pharmacological properties
Naphazoline is an alpha2-adrenergic agonist and has a rapid, pronounced and long-lasting vasoconstrictor effect on the vessels of the mucous membranes (reduces swelling, hyperemia, exudation). Facilitates nasal breathing during rhinitis. After 5-7 days, tolerance occurs.
Indications for use
- acute rhinitis,
- sinusitis,
- eustachitis,
- laryngitis,
- to facilitate rhinoscopy,
- the need to stop nosebleeds.
Contraindications
- hypersensitivity to the components of the drug,
- chronic rhinitis, arterial hypertension,
- pronounced atherosclerosis,
- tachycardia,
- thyrotoxicosis,
- diabetes,
- simultaneous use of MAO inhibitors and a period of up to 14 days after the end of their use,
- children under 15 years of age.
Directions for use and doses
The bottle of emulsion must be shaken before use.
Use an open bottle of the drug within 4 weeks.
Doses for adults:
1-3 drops in each nasal passage 2-3 times a day.
Use short-term, no more than 1 week. If nasal breathing becomes easier, then the use of Sanorin with eucalyptus oil can be stopped earlier. Repeated use of the drug is possible after a few days.
Side effect
Nausea, tachycardia, headache, irritability, allergic reactions, rash, increased blood pressure, reactive hyperemia, swelling of the nasal mucosa.
Local side effect: when used for more than 1 week - irritation, in some cases - swelling of the nasal mucosa.
Overdose
Long-term or frequent use of Sanorin with eucalyptus oil in the nasal cavity can cause swelling of the nasal mucosa and a feeling of stuffiness. The danger of overdose (especially if swallowed) of Sanorin with eucalyptus oil occurs in young children and can cause depression of the central nervous system with the following symptoms: drowsiness, decreased body temperature, increased sweating, slowed heart rate, increased blood pressure or its subsequent decrease, Coma is extremely rare.
Treatment: symptomatic.
Interaction with other drugs
Concomitant use with MAO inhibitors and for a period of up to 14 days after the end of their use increases the risk of developing severe arterial hypertension (release of deposited catecholamines under the influence of naphazoline). Slows down the absorption of local anesthetics.
special instructions
With long-term use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and therefore it is recommended to take a break for several days after 5-7 days of use. May have a resorptive effect.
Consult your doctor about the advisability of using Sanorin with eucalyptus oil with other medications.
Release form
10 ml of the drug in brown glass bottles, equipped with a SANO dropper with a polyethylene cap, a security tape to control the first opening of the original and a label. Each bottle is placed in a cardboard box with instructions for use.
Best before date
4 years
The drug should not be used after the expiration date indicated on the packaging.
Storage conditions
Store at a temperature from 10°C to 25°C, protected from light and out of reach of children.
Conditions for dispensing from pharmacies:
Over the counter.Manufacturer
IVEX Pharmaceuticals s.r.o., Czech Republic
74770, Czech Republic, Opava-Komarov, Ostravska str., 29 / Ostravska 29, 74770 Opava-Komarov, Czech Republic
Address for receiving complaints:
Russia, Moscow, 119049,
st. Shabolovka, 10, building 2, Business Center "Concord"
The drug "Sanorin" is an anticongestive drug. It is an alpha adrenergic agonist that has a direct stimulating effect on alpha adrenergic receptors of the sympathetic nerve system. The intranasal drug "Sanorin" is especially often used for children. Parents' reviews of him are mostly positive.
Pharmacological properties
After instillation into the nose, the medicine quickly produces a pronounced and long-lasting vasoconstrictor effect on the vessels of the mucous membranes of the nasopharynx, nose, and paranasal sinuses. The drug relieves hyperemia and swelling, due to which the patency of the nasal passages improves and breathing becomes easier. At the same time, patency is also restored. As a rule, the therapeutic effect develops within five minutes after intranasal administration and lasts for four to six hours.
Indications for use
The instructions for the medicine “Sanorin” for children indicate use for acute rhinitis of any etiology, sinusitis, otitis media (used as an additional drug to reduce swelling of the nasopharyngeal mucosa), laryngitis, eustachitis. Medicine is also prescribed during diagnostic and therapeutic procedures, when there is a need to relieve swelling of the sinuses and mucous membranes of the nose, and, if necessary, stop nosebleeds.
Release form. Compound. Price
The drug "Sanorin" for children is available in three versions. These are drops, spray and emulsion. The active ingredient of each dosage form is naphazoline nitrate. Spray and drops are a clear, colorless solution, and the emulsion is a white liquid. The medicine in any version is dispensed in ten milliliter bottles. Naphazoline nitrate in ten milliliters of drops contains 0.005 or 0.01 grams, spray - 0.01 grams, emulsion - also 0.01 grams. The secondary ingredients in the spray and drops are boric acid, water, ethylenediamine, methyl parahydroxybenzoate. The emulsion contains, in addition to the above, essential liquid paraffin and cholesterol as auxiliary components.
You can buy Sanorin for children at any pharmacy. The price of drops of concentration 0.05 percent averages 83-97 rubles, 0.1 percent - 76-85 rubles. The cost of the spray varies between 117-134 rubles, and for a bottle of emulsion you will have to pay about 90-119 rubles.
Is Sanorin safe for children?
Doctors often hear this question from concerned parents. The main thing is to avoid overdose. And for this you should use a solution of the required concentration. Thus, the drug “Sanorin” (for children) is specially produced in a concentration of 0.05%. It can be used by children from the age of two. A medicine containing 0.01 grams (0.1%) of the active ingredient can also be used for children, but only from the age of fifteen. It is not suitable for younger children. It is also recommended to use an ordinary glass pipette for instilling the drug in small children, rather than a factory-made dropper package - this way you will definitely avoid an overdose and will not harm the baby.
Dosage
In the form of drops, the drug “Sanorin” (for children), the instructions advise using one or two drops twice or thrice a day in each nasal passage. Children over fifteen years of age can use drops at a concentration of 0.1 percent, spray or emulsion and use an adult dosage: one to three drops or one to three doses in each nasal passage two to three times a day. The interval between instillations should be at least four hours. The instructions for using the medicine “Sanorin” for children recommend short-term use, no more than three days. If breathing through the nose becomes easier faster, you can stop using the drug earlier. It is allowed to start using the product again only after several days.
If you use the drug for more than a week, chronic obstruction of the nasal passages and atrophy of the nasal mucosa may develop. In rare situations, rebound hyperemia occurs. The medicine can also produce a resorptive effect. Due to the general effect on the body and irritation of the sympathetic nerve system, in extremely rare cases allergic reactions can develop.
Contraindications for use
It is prohibited to use Sanorin spray and drops for children if the patient is intolerant to the components of the product, suffers from atrophic or chronic rhinitis, severe eye diseases, or tachycardia.
Overdose
If you use the medication systemically, symptoms such as increased sweating, tremor, nervousness, increased blood pressure, tachycardia, and headache may develop. There is also a possibility of cyanosis, nausea, mental and respiratory disorders, and the temperature may rise. When the central nervous system is depressed, drowsiness, bradycardia, decreased temperature, weakness, collapse, and in extremely rare cases, coma are observed. It is worth remembering that children are much more sensitive to this type of drug than adults, so their risk of overdose increases significantly.
Drug interactions
When used simultaneously with monoamine oxidase inhibitors, as well as for fourteen days after their discontinuation, blood pressure may increase, since in this case the deposited catecholamines are released under the influence of naphazoline. Therefore, such combined use is prohibited. The drug can also slow down the absorption and prolong the effect of local anesthetics.
Nasal drops Sanorin is a medicine used to treat a wide range of inflammatory diseases of the respiratory and hearing organs. The main use of Sanorin is to ease breathing and relieve swelling. The drug is known for its rapid vasoconstrictor effect and the presence of various dosage forms.
Effect of the drug
The main active ingredient of the drug is Naphazoline. It is a decongestant and has a long-lasting vasoconstrictor and antiallergic effect when applied to the mucous membrane of the nasal cavities. Naphazoline is quickly absorbed into the body, which allows the patient’s condition to improve in a short time.
Vasoconstriction promotes the free removal of mucus during sinusitis and reduces the possibility of rapid proliferation of bacteria in the nasopharynx. For rhinitis and nasal congestion Sanorin cold drops restore nasal breathing and have an anti-inflammatory effect.
Forms of release of the drug
Sanorin is available in various dosage forms:
- nasal drops 10 ml. Sanorin nasal drops are produced in glass bottles with a dropper dispenser, thanks to which the number of drops is easily controlled;
- nasal spray 10 ml. Sanorin nasal spray is intended for irrigation of the mucous membrane. As a result of spraying, the drug is distributed in a thin layer throughout the nasal cavity and penetrates into the sinuses;
- emulsion Sanorin. Contains natural eucalyptus oil. Has a longer lasting effect than the previously listed forms;
- Sanorin Analergin. It is used both in the treatment of acute runny nose and conjunctivitis. The drug is instilled into the eyes to reduce swelling and redness of the eyelids.
Thanks to a good selection of dosage forms, Sanorin is widely used in the treatment of ENT diseases. When treating adults, use Sanorin nasal drops 0.1% solution, spray or emulsion with eucalyptus. A 0.05% solution is suitable for children. The use of drops and spray is possible in adults and children with the choice of the appropriate concentration of the active substance.
Sanorin with eucalyptus is not available for children, as this additive can irritate the child’s sensitive mucous membrane and cause discomfort in the nasopharynx, such as burning and bronchospasm. Also, Sanorin with eucalyptus should be used with caution by people susceptible to allergic reactions.
Use of the drug
Sanorin has the following range of indications: acute and allergic rhinitis, sinusitis, rhinosinusitis, sinusitis, sinusitis, eustachitis, laryngitis.
The drug is also used during rhinoscopy and to stop nosebleeds. In some cases, its use for the treatment of inflammation of the mucous membrane of the eyes is justified.
The daily dose of the drug for adults is from one to three drops in each nasal passage two or three times a day every 4 hours. For children, the following dosage is used: from the age of two to 6 years - one drop two, three times a day, from the age of six to 15 years - two drops two, three times a day.
Sanorin spray is not used to treat children under 15 years of age. For adults, the dosage is one or three irrigations of the nasal passages two to three times a day, maintaining an interval of at least four hours between uses.
We must not forget that long-term use of the drug in both adults and children can lead to dependence on vasoconstrictor drops. Therefore, the period of use in adults is limited to seven days; in children it should last no more than five days.
Use for sinusitis
A complication of acute rhinitis can be sinusitis - bacterial inflammation of the paranasal sinuses. Can Sanorin cure sinusitis, or prevent its development? One of the causes of sinusitis is swelling of the nasal mucosa, which blocks the passage between the nasal cavity and the adjacent sinuses. As a result of its closure, purulent discharge accumulates in the sinuses.
Therefore, the basis for the treatment of sinusitis consists of procedures aimed at reducing the severity of swelling of the mucous membrane to ensure the free passage of accumulated mucus. That is why, in drug treatment, the first step is to use drugs that have a vasoconstrictor and anti-inflammatory effect, which includes Sanorin.
You need to use Sanorin for sinusitis by adhering to certain rules:
- you need to lie on your side;
- then drip the medicine first into one nostril, remaining in this position for about five minutes;
- then repeat the instillation, turning over to the other side.
After using this drug and completely freeing the nasal passages, instillation of other medications is carried out, as well as rinsing. Sanorin for sinusitis turns out to be a priority and necessary medicine . With timely and competent use, the drug will help avoid surgical intervention.
Contraindications and side effects
Taking the drug Sanorin is contraindicated for people with chronic rhinitis, diseases of the cardiovascular system (arterial hypertension, angina, tachycardia), glaucoma, atherosclerosis, diabetes, with the risk of allergic reactions to the components included in the composition.
Relative contraindications include pregnancy and breastfeeding. The decision to use the drug in each case is made by the attending physician on an individual basis. In the presence of vascular pathologies and the risk of high blood pressure, the drug is not prescribed during pregnancy. The use of Sanorin in children under two years of age is prohibited.
Side effects of Sanorin are quite rare. These include the following reactions: weakness, headache, agitation, tachycardia, increased blood pressure.
The drug is sold in pharmacies without a doctor's prescription and, if instructions and precautions are followed, is a good remedy for the fight against the common cold. Timely use of Sanorin is the prevention of complications. Sanorin eliminates the cause of sinusitis, relieves swelling of the mucous membrane and helps prevent purulent inflammation of the maxillary sinuses.
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In addition to local effects on blood vessels, naphazoline is absorbed and enters the general bloodstream. When used correctly, its content in the blood is too low to affect other organs and systems. In cases of frequent use during the day, the concentration of naphazoline in the blood becomes quite high, which affects the normal functioning of the cardiovascular system ( of cardio-vascular system) and kidneys. This fact must be taken into account by people suffering from cardiovascular diseases. By affecting the heart, it can cause an increase in the frequency of its contractions, and also lead to an increase in blood pressure ( blood pressure).
Types of Sanorin
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Today there are four trade names for this drug. They differ in that they contain various active and auxiliary substances. Thanks to these substances, sanorin from different manufacturing companies, to one degree or another, shows better effectiveness in certain diseases.
Types of Sanorin
Name of the medication | Active substance | Excipients | Release form |
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Sanorin | Naphazoline nitrate | Ethylenediamine, boric acid, methyl parahydroxybenzoate, water. |
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Sanorin-Analergin | Naphazoline nitrate + Antazoline mesylate | Diseases for which Sanorin is used are:
Contraindications to the use of Sanorin![]() Contraindications to the use of Sanorin include:
Method of application and dosage of sanorin in children and adults![]() Dosage of the drug Sanorin
The maximum duration of treatment for adults and children over 15 years of age is 1 week. Further use loses its effectiveness and significantly increases the risk of side effects. Sanorin-Xylo for all age groups is used for no more than 3 – 5 days. Use of Sanorin in childrenChildren need to use only a special children's form of Sanorin. It differs in that the concentration of the active substance contained in the drug is reduced by 2 times compared to sanorin for adults. An attempt to use the adult version in children in most cases leads to side effects. For children under 15 years of age, the use of Sanorin should not exceed 3 to 4 days, after which it is necessary to take a break, regardless of the results of treatment.Sanorin with eucalyptus oil should not be used by children under 15 years of age. Due to the presence of many different substances in eucalyptus oil, the risk of allergic reactions in children increases significantly. Special instructions for the use of SanorinFor more effective treatment with this drug, there are a number of manipulations necessary to facilitate the delivery of the drug to its destination. Not all patients receive the desired effect from treatment with Sanorin, and it is necessary to take a break before restarting use.Special instructions for the use of sanorin are as follows:
Side effects of sanorin![]() Side effects are divided into two groups:
Local adverse reactionsLocal side effects develop in the area of application of the drug. On the one hand, the mechanism of their appearance is associated with a pronounced long-term narrowing of small vessels and impaired microcirculation in the area of the nasal mucosa. On the other hand, local side effects develop due to stimulation of adrenergic receptors of mast cells, resulting in increased release of histamine, one of the main mediators of inflammatory reactions.Local undesirable effects are:
Common adverse reactionsDue to the fact that the drug sanorin has a predominantly local effect, general side effects are observed relatively rarely, but the possibility of their occurrence should not be completely excluded. In high dosages and with prolonged use of the drug, absorption of the active substance into the bloodstream and stimulation of peripheral adrenaline receptors is possible. Common adverse reactions are associated with a stimulating effect on receptors located in the blood vessels, heart, smooth muscles of the digestive tract, and in the iris of the eyes. The severity of systemic side effects may vary from minor to moderate, which may require you to refrain from further use of sanorin.Side effects from the cardiovascular system are:
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A runny nose, or acute rhinitis, is characterized by nasal congestion, impaired nasal breathing and the appearance of a large amount of nasal discharge. Sanorin can help children cope with these phenomena. However, it should be noted that it is undesirable to take this drug without a doctor’s prescription due to some unpleasant phenomena.
Can children have Sanorin?
Many mothers are interested in whether it is possible for children to take Sanorin drops into their noses when they have a runny nose? We will try to give a detailed answer.Sanorin is a drug containing an active component called naphazoline. This substance belongs to the group of alpha-adrenergic agonists, and has an effect on blood vessel receptors similar to the effect of adrenaline.
Experts know the vasoconstrictor effect of adrenaline, but it has an effect on almost the entire body, which alpha-adrenergic agonists lack.
Sanorin for children is available in a special concentration - 0.05% of the active substance in solution. If you are planning to use this drug to treat your child, you should memorize this number. Under no circumstances should 0.1% Sanorin be used for children.
Studies conducted by some medical institutions have shown a direct link between drug overdose and use of the drug in inappropriate concentrations.
The use of factory-made dropper packaging also leads to an overdose. Studies have shown that it is impossible to accurately dose the drug using an authentic dropper. The dose of the drug can be exceeded 10 times!
According to experts, it is better to use Sanorin for children using a regular glass pipette.
Sanorin has a local vasoconstrictor effect, as a result of which hyperemia and swelling of the nasal mucosa are reduced, fluid exudation and, accordingly, the amount of discharge are reduced. The result of these processes is the disappearance of nasal congestion and easier nasal breathing.
The downside of using Sanorin is some burning in the nose, which, however, quickly disappears. The effect of Sanorin develops within 3-5 minutes and lasts from 3 to 6 hours. After this time, the effect of the drug begins to gradually weaken. This allows Sanorin to be used for children (the price of the drug allows it to be used quite widely) 3-4 times a day.
It should be mentioned that the drug should be used for no more than three days due to the so-called tachyphylaxis. The body quickly gets used to the administration of the drug and stops responding to it. Therefore, even if the symptoms of rhinitis do not go away, you should stop taking the drug after 3 days and switch to other medications (your doctor will tell you which ones).
Sanorin for children, instructions
According to the instructions, Sanorin for children can be used, as previously written, only in a special children's concentration - 0.05%. The drug can be instilled starting from the age of two.If, in addition to rhinitis, the child has other symptoms of an infectious disease - fever above 38 degrees, weakness, headache, drowsiness - in addition to using nasal drops, you should definitely consult a doctor. It is quite possible that the virus that caused the disease is the influenza virus, and it should be treated comprehensively under the guidance of an experienced specialist.
Sanorin, indications and contraindications
Indications and contraindications for Sanorin can be read in the instructions.The drug is used for acute rhinitis, sinusitis, inflammation of the Eustachian tube, laryngitis, nosebleeds, and as a preparation for rhinoscopy. Sometimes Sanorin is also used in ophthalmology as an element of complex therapy for bacterial conjunctivitis (a 0.05% solution is used).
Contraindications to Sanorin are: chronic rhinitis, arterial hypertension, closed-angle glaucoma, disorders of the cardiovascular system - arterial hypertension, severe atherosclerosis, some heart rhythm disorders. Endocrine disorders such as thyrotoxicosis and diabetes mellitus also interfere with the use of Sanorin.
In addition, the drug is absolutely contraindicated for children under 2 years of age, and from 2 to 15 years of age only 0.05% nasal drops can be used.
Sanorin spray can be given to children only after 15 years.
So, Sanorin is recognized as an effective and relatively safe remedy for the fight against the common cold. However, it should be noted that this drug can in no way serve as a treatment for a viral infection. This medicine will only eliminate the symptoms, and complex effective therapy for diseases that cause acute symptoms can only be prescribed by a qualified specialist.
Instead of simply dripping Sanorin into your children’s noses, consult your doctor for the correct and safe prescriptions.