Nicotinic acid nn name. Vitamin PP (niacin). Therapy control, precautions

Nicotinic acid has found wide application in the field of medicine, due to its wide spectrum of action. In particular, with the help of this drug it is possible to dilate blood vessels, improve blood circulation, and regulate the redox balance in the body. Nicotinic acid or nicotine is used in the treatment of various types of diseases. Let’s find out in more detail what is included in nicotine, as well as the types of diseases for which this drug is prescribed for use.

Composition and pharmacology of the drug

Nicotinic acid is a vitamin preparation that affects metabolic processes in body tissues. Nicotine is vitamins PP, B3 and niacin, which are naturally found in foods such as vegetables, fruits, fish, dairy products, walnuts, peas, beef liver and others. If a person does not have health problems, then the intake of these vitamins by consuming the above products is sufficient. If a person is sick, then the body’s need for nicotinic acid increases significantly.

It is important to know! Nicotine is included in various medications, thereby dilating blood vessels, increasing blood fluidity, stabilizing cholesterol levels in the blood, and preventing the development of thrombosis.

Indications for the use of this medication are associated with the development of neurological pathologies. The introduction of PP vitamins into the body promotes a beneficial effect on nerve cells. Nicotinic acid helps increase the transmission of nerve impulses and also improves the effect of nerve cell regeneration. Positive dynamics are reflected in blood pressure, as a result of which its readings stabilize. Nicotine helps to dilate blood vessels, which speeds up the healing and regeneration of wounds.

The drug Nicotinic acid is available in the form of tablets and 1% injection solution. If chronic headaches and migraine attacks occur, patients are advised to undergo maintenance therapy using nicotine. Nicotinic acid in the form of injections is prescribed by the attending physician for appropriate indications.

When is it recommended to use nicotine?

The daily requirement for a healthy person of nicotinic acid is 25 mg. Patients need to increase this norm if the following factors are present:

With excessive mental and physical activity.
With excessive stress on the nervous system.
When the activity is caused by harmful working conditions.
In case of bad ecology.

In addition to preventive purposes, nicotinic acid has the following indications for use, caused by the following types of ailments:

In case of open wounds that do not heal for a long time.
In the event of ischemic diseases.
For muscular and neurogenic dystrophies.
With the development of atherosclerosis and endarteritis.
For disturbances of blood flow in brain tissues and vessels.

Nicotinic acid also has the following indications for use: hemorrhoids, liver disease, alcohol intoxication, drug intoxication. Nicotine helps improve memory, vision, hearing, and also accelerates the breakdown of fats for rapid weight loss.

Instructions for use of the drug

Medication treatment is prescribed by the attending physician if there are appropriate indications. Patients must be aware that an overdose of the drug should not be allowed, as this will lead to serious consequences. It is required to comply with the dosage, as well as adhere to the correct course of treatment, which was prescribed by the doctor or as indicated in the instructions for using nicotine in the form of injections.

Nicotinic acid solution is intended exclusively for intravenous administration at a dosage of 1-2 ml per day. Intramuscular administration of the drug causes severe pain, so this option is not acceptable. When administering the drug intravenously, the patient must lie in a horizontal position. The injection should be administered as slowly as possible, which will promote better distribution in the bloodstream. If the medication is introduced into the bloodstream at an accelerated rate, this will lead to severe dizziness, hypertension and increased body temperature.

It is important to know! Tablets are taken for preventive purposes, and injection is administered if therapeutic therapy is necessary. After completing a course of treatment with injections, additional use of the tablet form may be prescribed.

The duration of treatment with nicotinic acid can be 10-15 days, but the duration of therapy is prescribed by the doctor. In rare cases, when a decision is made to administer the medication intramuscularly, lidocaine is necessarily used.

Contraindications to the use of the drug

The drug Nicotinka is used for both adults and children, only over the age of 15 years. It is prohibited to use the drug for pregnant women, as well as young mothers who are breastfeeding. A number of contraindications for the use of the medication include:

People with diabetes and liver pathologies.
With high blood pressure.
If the patient has signs of individual intolerance to the drug.
Patients who have stomach problems: ulcers, gastritis.

If one of the above contraindications is present, it is necessary to exclude the use of the drug, since the consequences can cause side symptoms and deterioration of well-being.

Side effects

Improper use of Nicotine can cause a number of different serious side effects. To prevent the occurrence of such actions, the drug should be used only as prescribed by a specialist. Side symptoms include:

redness of the skin, causing signs of burning and tingling;
dizziness, which may occur with accelerated injection;
feeling of excess blood in the brain;
hives and swelling;
increased secretion of gastric juice;
hypotension.

Adverse symptoms may occur with prolonged use of the drug if this is not necessary. Such symptoms appear as:

Diarrhea.
Vomiting and nausea.
Arrhythmia.
Decreased glucose tolerance.
Irritation of the gastric mucosa.

It is important to know! It is prohibited to administer the drug by injection yourself, as this responsibility rests with medical personnel.

If any deviations or deterioration in health occur when using Nicotine, you should immediately call an ambulance or inform your doctor.

Treatment of osteochondrosis with nicotine

One of the main reasons for the development of osteochondrosis is the lack of nutritional components in the cartilaginous plates of the spine. This deficiency is expressed in the development of such pathologies as degenerative-dystrophic changes. As the disease progresses, discs and bone tissue are destroyed. To stop the destruction process, nicotinic acid is used. Moreover, this substance is used in combination with vasodilating drugs.

When treating osteochondrosis with Nicotinic acid, an improvement in peripheral blood flow is observed, as well as a decrease in the likelihood of damage to nerve cells from hypoxia, that is, insufficient oxygen. To treat osteochondrosis with nicotine, it is important to follow the following important recommendations:

To achieve the maximum possible therapeutic effect, you need to make sure that the patient really does not have enough of these vitamins in his body.
It is necessary to treat osteochondrosis with vitamins correctly, that is, therapy should be carried out in courses in compliance with certain dosages.
During therapy for the treatment of osteochondrosis, it is mandatory to monitor blood counts.

Cost and conclusions

The package of the drug Nicotinic acid contains 10 ampoules, each of which contains 1 ml of medication. The cost of a package of Niacin is 100-150 rubles. Prices in pharmacies may vary slightly. It is recommended to store ampoules in a dark and cool place. After the end of its service life, be sure to recycle it.

In conclusion, it is worth noting that Nicotinka is an inexpensive and effective vitamin preparation, after the use of which patients observe an improvement in the condition of the skin, accelerated wound healing, the disappearance of pain in the spine, and a clearer head.

Nicotinic acid is a vasodilator and antipellagritic agent.

Release form and composition

Tablets (10 pcs. in blister packs; 10 pcs. in blister packs, 5 packs in a cardboard pack; 50 pcs. in dark glass, polymer or polypropylene jars; 50 pcs. in dark glass, polymer or polypropylene jars cans, 1 can in a cardboard pack);
Solution for injection (1 ml in ampoules, 5 ampoules in blister packs, 1 or 2 packs in a cardboard box).

Active ingredient: nicotinic acid:

1 tablet – 50 mg;
In 1 ml of solution – 10 mg.

Indications for use

Hypo- and vitamin deficiency PP;
Hartnup's disease (a hereditary disease characterized by impaired absorption of certain amino acids, including tryptophan).

Nicotinic acid is also used as part of combination therapy for the following diseases:

Ischemic stroke;
Neuritis of the facial nerve;
Obliterating diseases of the vessels of the extremities (Raynaud's disease and obliterating endarteritis);
Diabetes mellitus and its complications, such as microangiopathy and diabetic polyneuropathy.

Contraindications

Absolute:

Gout;
Atherosclerosis;
Cirrhosis of the liver;
Hepatitis;
Hyperuricemia;
Exacerbation of peptic ulcer of the stomach and duodenum;
Decompensated diabetes mellitus;
Hypersensitivity to nicotinic acid.

Relative (the drug should be used with extreme caution due to the risk of complications):

Peptic ulcer of the stomach and duodenum in remission;
Hyperacid gastritis;
Arterial hypotension;
Glaucoma;
Hemorrhages;
Childhood;
Pregnancy;
Lactation.

Directions for use and dosage

Pills

The tablets should be taken orally after meals.

Prevention: adults – 15-25 mg, children – 5-20 mg per day;
Treatment of pellagra: adults – 100 mg 2-4 times a day, children – 5-50 mg 2-3 times a day;
Other diseases: adults - 20-100 mg, with hypercholesterolemia the daily dose can be increased to 2000-3000 mg, children - 5-30 mg 2-3 times a day.

Injection

For pellagra, 1 ml is administered intramuscularly, intravenously or subcutaneously 2-3 times a day for a course of 10-15 days.

For ischemic stroke, nicotinic acid is administered slowly intravenously at a dose of 10 mg.

For other indications, 10 mg is usually prescribed 1-2 times a day for 10-15 days.

The maximum permissible single dose for adults is 100 mg, daily – 300 mg.

For Hartnup disease, the daily therapeutic dose can vary from 40 to 200 mg.

Side effects

Cardiovascular system: hyperemia of the skin of the face and upper half of the body, rush of blood to the scalp, headache, feeling of heat, orthostatic hypotension, collapse; with rapid intravenous administration - dizziness, significant decrease in blood pressure;
Central and peripheral nervous system: dizziness, paresthesia;
Metabolism: with long-term use - asthenia, decreased glucose tolerance, hyperuricemia, increased blood levels of aminotransferase, lactate dehydrogenase, alkaline phosphatase;
Digestive system: with long-term use – fatty liver;
Other: allergic reactions (skin itching, skin rash, urticaria, wheezing);
Local reactions with intramuscular and subcutaneous administration: pain.

special instructions

Liver function should be monitored during treatment. To prevent complications, include foods containing methionine (for example, cottage cheese) in your diet, or take lipoic acid, methionine and other lipotropic drugs.

Drug interactions

Sulfonylurea: increases blood glucose levels;
Lovastatin: risk of developing myopathy;
Neomycin: its toxicity is reduced, the decrease in the concentration of high-density lipoproteins and cholesterol induced by it is prevented.

Particular caution should be exercised in the case of simultaneous use of ascorbic acid, anticoagulants and antihypertensive drugs.

Nicotinic acid group (vitamin PP).

Composition Nicotinic acid

The active substance is nicotinic acid.

Manufacturers

Akrikhin KhFK (Russia), Biomed (Russia), Veropharm Belgorod branch (Russia), Vitamins (Ukraine), Dalkhimfarm (Russia), Irbit Chemical and Pharmaceutical Plant (Russia), Moskhimfarmpreparaty im. ON THE. Semashko (Russia), Ufavita (Russia), Pharmstandard-Leksredstva OJSC (Russia), Pharmstandard-Ufa Vitamin Plant (Russia)

pharmachologic effect

Replenishes vitamin PP (B3) deficiency, vasodilating, hypolipidemic, hypocholesterolemic.

Included in the prosthetic group of enzymes that transport hydrogen:

nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP,
regulates the redox process,
tissue respiration,
synthesis of proteins and fats,
glycogen breakdown.

Inhibits lipolysis in adipose tissue, reduces the rate of VLDL synthesis.

Normalizes blood lipid composition:

reduces total cholesterol levels,
triglycerides and increases LPV levels,
has antiatherogenic properties.

Has a vasodilating effect, incl. on cerebral vessels, improves microcirculation, increases fibrinolytic activity of the blood and reduces platelet aggregation (reduces the formation of thromboxane A2).

Has detoxifying properties.

Shows effectiveness in Hartnup's disease - a hereditary disorder of tryptophan metabolism, accompanied by a deficiency in the synthesis of nicotinic acid.

Well absorbed in the pyloric part of the stomach and the upper parts of the duodenum.

Partially biotransformed in the liver with the formation of N-methylnicotinamide, methylpyridonecarboxamides, glucuronide and a complex with glycine.

Excreted in urine.

Side effects Nicotinic acid

Due to the release of histamine:

skin redness,
incl. face and upper body with a tingling and burning sensation,
feeling of a rush of blood to the head,
dizziness,
hypotension,
orthostatic hypotension (with rapid intravenous administration,
increased secretion of gastric juice,
dyspepsia,
hives.

With long-term use of large doses:

diarrhea,
anorexic,
vomiting
liver dysfunction,
fatty liver degeneration,
ulceration of the gastric mucosa,
arrhythmias,
paresthesia,
hyperuricemia,
decreased glucose tolerance,
hyperglycemia,
transient increase in AS activity,
alkaline phosphatase,
irritation of the gastrointestinal mucosa.

Indications for use

Prevention and treatment of pellagra (vitaminosis PP); atherosclerosis, hyperlipidemia, peripheral vascular spasm, incl. obliterating endarteritis, Raynaud's disease, migraine, cerebrovascular accident, including ischemic stroke (complex therapy), angina pectoris, Hartnup disease, hypercoagulation, facial nerve neuritis, intoxication, long-term non-healing wounds, ulcers, infectious diseases, gastrointestinal diseases.

Contraindications Nicotinic acid

Hypersensitivity, peptic ulcer of the stomach and duodenum (in the acute stage), severe liver dysfunction, gout, hyperuricemia, severe forms of arterial hypertension and atherosclerosis (iv administration).

Restrictions on use:

pregnancy,
lactation.

Directions for use and dosage

For prevention:

adults – 0.0125-0.025 g per day,
children - 0.005-0.025 g per day.

For pellagra:

adults – 0.1 g 2-4 times a day for 15-20 days;
children - 0.0125-0.05 g 2-3 times a day.

For atherosclerosis:

2-3 g per day in 2-4 doses.

For lipid metabolism disorders:

internal,
the dose is gradually increased (in the absence of side effects) from 0.05 g once a day to 2-3 g per day in several doses,
course of treatment – 1 month or more,
Between repeated courses, breaks are necessary.

For other diseases:

adults – 0.02-0.05 g (up to 0.1 g) 2-3 times a day,
children - 0.0125-0.025 g 2-3 times a day.

Overdose

No data.

Interaction

Potentiates the effect of fibrinolytic agents, antispasmodics and cardiac glycosides, the toxic effect of alcohol on the liver.

Reduces the absorption of bile acid sequestrants (an interval of 1.5–2 hours between doses is required) and the hypoglycemic effect of antidiabetic drugs.

Possible interaction with antihypertensive drugs, acetylsalicylic acid, anticoagulants.

special instructions

Use with caution for hyperacid gastritis, gastric and duodenal ulcers.

Liver function should be regularly monitored during treatment.

To prevent hepatotoxicity, it is necessary to include foods rich in methionine (cottage cheese) in the diet, or prescribe methionine or other lipotropic agents.

It is not advisable to use for the correction of dyslipidemia in patients with diabetes mellitus.

It should be borne in mind that subcutaneous and intramuscular injections are painful.

Storage conditions

List B.

In a dry place, protected from light, at room temperature.

Nicotinic acid is rightfully considered the most important substance for the human body. Its other names are niacin, nicotine, vitamin B3 or PP. The main task of nicotinic acid is to convert food consumed by a person into energy. The significance of this medicine for the success of recovery processes and the treatment of many diseases is beyond the slightest doubt. Nicotinic acid is produced in two forms: tablets and liquid for injection. It should be taken only as prescribed by a doctor - like all medications, nicotinic acid has contraindications for use.

Indications for use

The composition of nicotinic acid is unique. The main advantage of this medicinal substance is its powerful antipellagric action. Therefore, it is nicotinic acid that is recommended to be taken by patients diagnosed with pellagra. Another name for the drug is vitamin PP. If treatment with nicotinic acid is started in a timely manner, at the initial stage of the disease, the chances of complete recovery are quite high. The main thing is to follow all the doctor’s instructions.

Nicotinic acid, which helps improve carbohydrate metabolism in the body, is widely used to treat:

Mild form of diabetes.
Liver and kidney diseases.
Heart disease.
Stomach ulcers.
Duodenum.
Inflammatory processes in the small and large intestine.
Wounds and ulcers.

Nicotinic acid is also often used as a vasodilator. It is also used to reduce the amount of lipoproteins in the blood - for this purpose the patient is prescribed 3-4 grams. nicotinic acid per day. The dose is undoubtedly high. But in this situation it is appropriate and effective.

Doctors often prescribe nicotinic acid to patients with hypercholesterolemia, a pathological condition of the body in which the level of cholesterol in the blood is abnormally high. Nicotinic acid not only reduces the concentration of cholesterol in the blood, but also improves general condition. It is also used to treat diseases of the stomach and liver (including in patients with low acidity):

Gastritis.
Inflammatory processes.
Acute hepatitis.
Liver cirrhosis.
Spasms.

Nicotinic acid promotes the healing of wounds and ulcers - even those that other medications cannot cope with. It is also part of complex therapy in the treatment of inflammation of the facial nerve, atherosclerosis and most infectious diseases.

Osteochondrosis is a degenerative change in cartilage tissue, leading to the destruction of joints, thinning of the vertebral discs and ligaments, the development of inflammatory processes and the appearance of intervertebral hernias. The spine becomes less flexible and mobile, the patient suffers from severe pain, sudden dizziness, constant nausea, noise and pain in the ears. Taking nicotinic acid (niacin) for osteochondrosis is the key to quickly improving your well-being and speedy recovery.

It is well known that for the prevention of osteochondrosis and in its treatment, proper nutritious nutrition plays an important role. The drug, being essentially a vitamin, replenishes the deficiency of nicotinic acid in the patient’s body.
The medicine helps improve blood circulation, thereby stimulating tissue nutrition.
The substance provides cells with protection from free radicals and prevents their damage.
Nicotinic acid helps the body get rid of toxins, heal and rejuvenate tissues.
Thanks to taking the medicine, metabolism improves and waste waste is removed from the body.
Acid restores damaged neuron structures, helping to renew nerve tissue and preventing the inflammation process from starting.

Proper Use

Nicotinic acid is prescribed in two forms - in the form of tablets and solutions for injections or injections. The drug is used both for the treatment of diseases and for their prevention. The daily preventive dose for an adult should not exceed 0.025 g, for a child – 0.005 g.

The course of treatment for pellagra with nicotinic acid tablets is at least two weeks. You need to take the medicine 3-4 times a day, 0.1 g. The course of treatment with the solution is longer - eighteen days. For injections, use 1% nicotinic acid, administer the drug 1 ml in the morning and evening.

For the treatment of other diseases, doses of the drug are calculated by the doctor on an individual basis. For an adult patient, the daily dose of nicotinic acid is most often 0.04 g. Children are prescribed no more than 0.03 g. substances per day and it is recommended to divide its intake into several parts (2-3 times a day).

If nicotinic acid was prescribed for the treatment of osteochondrosis in combination with other medications, the healing process will accelerate significantly. This also applies to the treatment of cervical osteochondrosis. However, we are talking only about injections- Such a disease cannot be cured with pills. Manufacturers offer one percent solutions of nicotinic acid in ampoules - each containing 1 ml of the drug. The doctor will explain how to treat osteochondrosis. He will draw up an individual treatment regimen, according to which the injections will be given intramuscularly, intravenously or subcutaneously. The result of the injections will not be long in coming - the blood vessels will dilate, the blood supply to tissues will improve, the body’s metabolism will be restored, and the patient’s condition will stabilize.

Rules for administering the injection solution

The process of introducing nicotinic acid into a vein must be slow - otherwise the appearance of discomfort in the patient cannot be avoided. Subcutaneous and intramuscular injections of nicotinic acid require extreme caution from the person giving them - they are very painful. Therefore, such injections are excluded from medical practice today. Sodium nicotinate or nicotinamide can help minimize skin irritation - they are what experts recommend using.

Maximum dose

The maximum dose of nicotinic acid should not be exceeded under any circumstances. For an adult, a single dose is 0.1 g of the substance in tablet form. You can take no more than 0.5 g of the drug per day.

A single dose of nicotinic acid injection should not be more than 0.1 g, the daily maximum when injecting the substance into a vein is 0.3 g.

Doctors are of the opinion that the dose of tablets can be increased if necessary. However, only a doctor can make such a decision. When treating atherosclerosis and the patient's existing disorders in lipid metabolism, the daily dose of nicotinic acid can be increased to 0.5 g. But only if the patient has no side effects when taking the drug.

Side effects

Not all patients tolerate treatment with nicotinic acid well; some experience side effects while using the drug. Without a doubt, if the dosage was calculated correctly and the patient strictly followed the doctor’s recommendations, dangerous complications are excluded. However, when you first take the medicine it is possible:

Facial redness.
The appearance of slight dizziness.
Feeling of a rush of blood to the head.
The appearance of skin rashes.
Numbness of the limbs.
A sharp decrease in blood pressure (when the drug is administered into a vein).

Usually such unpleasant sensations go away within a couple of days. And they occur most often in those who take the pills on an empty stomach. However, in particularly sensitive patients, it is quite possible that allergic reactions may occur while taking nicotinic acid.

If the slightest discomfort occurs and unpleasant sensations that do not go away within two days, you should stop taking nicotinic acid. And immediately contact your doctor - he will adjust the dose or completely stop the drug.

Contraindications

If you have certain diseases, taking nicotinic acid is strictly prohibited. The drug is contraindicated if the patient has:

Severe form of hypertension.
Frequent increases in blood pressure.
Atherosclerosis in advanced form.
The likelihood of allergic reactions to nicotinic acid.
Stomach ulcer.
Diseases of the duodenum.
Problems with the liver and kidneys.
Hyperuricemia.
Neurosis.
Sinus tachycardia.
Nephrosclerosis.
Severe arrhythmia.
Inflammatory processes in the body.
Circulatory failure.

When taking nicotinic acid to patients diagnosed with such diseases, the risk of serious complications and dangerous side effects is quite high.

Overdose

Long-term use of nicotinic acid threatens such complications as fatty degeneration in the liver. To avoid such complications, doctors recommend that patients include foods rich in methionine and amino acids in their diet. If an overdose is established and the patient’s condition is of concern, he is prescribed prolipotropic drugs that interact with fats in the liver.

When taking a large dose of nicotinic acid, under no circumstances should you delay contacting a specialist. In especially severe cases, the patient will be placed in a hospital, where he will spend some time under medical supervision.

Possibility of use for children

Nicotinic acid is prescribed for the treatment of pellagra in children only in special cases. More often it is replaced with analogues - nicotinamide and sodium nicotinate, which are included in complex therapy (6-18 ml of medication per day). The same drugs are used to prevent pellagra.

Use during pregnancy

The use of nicotinic acid by pregnant women is strictly prohibited, regardless of the stage of pregnancy. The substances that make up the drug can harm not only the expectant mother, but also the unborn baby. Also, doctors categorically prohibit the use of the drug during lactation - nicotinic acid entering the baby’s body along with mother’s milk can cause irreparable harm to his health.

Driving while taking the drug

Nicotinic acid entering the body can cause dizziness and slow reaction. This is why doctors recommend stopping driving while taking the drug. Just like other activities that require special concentration, the risk of accidents and incidents is quite high.

Compatibility with other drugs

By interacting with certain medications, nicotinic acid enhances their effect. For example, the effect of taking cardiac glycosides increases significantly. Especially digitalis glycoside.

Doctors also warn against mixing solutions of substances such as nicotinic acid and cyanocobalamin in one syringe. Their combination is quite dangerous for the human body and can cause allergies and other side effects. In addition, the joint introduction of these drugs into the body leads to the destruction of cobalt vitamins.

You must inform your doctor if you are taking any medications. Only then will he be able to correctly calculate the required dosage of nicotinic acid, and, if necessary, reduce it.

pharmachologic effect

Nicotinic acid promotes the transport of phosphate, improves nitrogen and carbohydrate metabolism in cells, and is involved in the regulation of DNA synthesis. Quite often the drug is prescribed for the treatment of ulcers and wounds of any origin that do not heal for a long time due to the patient’s weakness.

Absorbed into the blood within half an hour and immediately beginning its restoration work, nicotinic acid gradually becomes an oxidizing compound in the cells and is excreted from the body along with urine within a short period of time.

Storage conditions

Ampoules and tablets of nicotinic acid must be stored in a dark place, inaccessible to children, at a temperature of no more than +23 C. Ready-made solutions must be used immediately - they cannot be stored without an ampoule. The shelf life of the drug itself (in original packaging) is no more than 5 years.

Price

Nicotinic acid is sold in pharmacies without a prescription. Approximate price of the drug:

Ampoules 1% - from 60 to 70 rubles (10 pieces).
Tablets of 50 mg - from 20 to 40 rubles (50 pieces).

The drug nicotinic acid belongs to the vitamin derivatives of pharmacological production. This drug has a number of effects on the human body. This allows it to be used effectively for many diseases.

Among the positive effects of nicotinic acid on the human body, the following should be noted:

metabolic action leads to normalization of metabolic processes, restoration of neural structure;
as vitamin nicotinic acid and instructions for use contain this information, it is responsible for lipid and carbohydrate metabolism in the human body;
Also, injections and tablets of nicotinic acid can restore impaired blood supply to some parts of the human body and brain;
vasodilation, which occurs under the influence of nicotinic acid, leads to normalization of oxygen metabolism and oxidative processes;
Nicotinic acid can also have a detoxifying effect, so it can be used for poisoning and alcohol consumption.

These are not all the positive properties of nicotinic acid; the instructions for use that we offer you will help you understand all the therapeutic effects. We hope to help you evaluate and use this drug.

Indications and use

The drug nicotinic acid has quite extensive indications for use. This drug can be taken both for medicinal purposes and for the prevention of many diseases.

In particular, nicotinic acid is used for medicinal purposes in the following diseases and conditions:

osteochondrosis of the spinal column of various parts;
ischemic stroke;
cerebrovascular accident;
noise in ears;
atherosclerosis;
pellagra;
impaired glucose tolerance;
circulatory disorders in the lower extremities;
haemorrhoids;
lipid metabolism disorders and obesity;
liver diseases;
alcohol intoxication;
drug intoxication;
occupational intoxication;
trophic ulcers of the lower extremities;
decreased visual acuity.

For prevention, nicotinic acid is used in:

reducing the risk of cancer;
rapid breakdown of fats and a decrease in the level of fatty acids entering the human body;
for gastritis with low acidity;
to eliminate the symptoms of hemorrhoids;
to improve memory and vision;
to speed up the process of fat breakdown when losing weight.

The use of nicotinic acid requires careful monitoring by the attending physician. Self-treatment with nicotinic acid is not allowed due to the fact that negative consequences may develop in the human body. Like any other vitamin preparation, if overdosed, it causes irreparable damage to your health.

Application of vitamin niacin

Very often, the vitamin nicotinic acid finds non-standard uses. In particular, this drug is very often used to rejuvenate and renew the skin of the face and body in many beauty salons. In fact, this is a completely justified method only if the treatment is carried out under the supervision of an experienced doctor.

Nicotinic acid has very different indications in this case. However, the principle of influence is quite simple.

This drug has a unique ability:

on the one hand, expand the vessels of the peripheral circulatory system;
on the other hand, it increases the supply of oxygen to tissues;
on the third hand, it increases the outflow and removal of free radicals and aggressive waste from skin cells.

All together this has a rejuvenating effect on the human body. This is best seen on the skin. The skin becomes smooth, moisturized and receives a pleasant pink tint.

Use of the drug in ampoules

Injections of nicotinic acid help to quickly introduce the drug into the human body and ensure its uniform distribution. Nicotinic acid in injections helps to avoid such negative side effects as irritation to the gastric mucosa. Nicotinic acid in ampoules is prescribed for:

increased acidity of gastric juice;
in acute ischemic cerebrovascular accidents;
for pain syndromes in the trigeminal nerve and spine;
for acute attacks of hemorrhoids.

Nicotinic acid is available in ampoules of 1 ml of 1% solution. Usually prescribed 1 ampoule subcutaneously, intramuscularly or intravenously once or twice a day.

How to give injections correctly

Nicotinic acid injections can be given in three ways:

intramuscularly 1 ml of 1% solution;
intradermally to compensate for vitamin deficiency;
intravenously, 1-5 ml of a 1% solution diluted in 5 milliliters of saline.

Intramuscular and intradermal injections of nicotinic acid are quite painful. There is a burning sensation. After an intravenous injection of nicotinic acid, you may experience heat and redness of the skin. This is a normal physiological reaction of the body. If redness is not observed, this may indicate that the person has certain problems with blood circulation.

Use of the drug in tablets

Nicotinic acid tablets can be used for prevention and long-term treatment of certain diseases. In particular, nicotinic acid tablets are recommended to be used twice a year, in spring and autumn, 1 month each, for people who suffer from problems with blood circulation in the lower extremities. Thrombophlebitis and venous insufficiency are a direct indication for the use of nicotinic acid in tablets over a long period of time.

The drug nicotinic acid in tablets is used depending on the person’s weight and the severity of the disease, 1-2 tablets 3 times a day. It is advisable at this time to introduce cottage cheese and other methionine-rich foods into your diet. This will help protect liver cells. In case of increased acidity of gastric juice, nicotinic acid tablets should be consumed after meals and washed down with plenty of mineral water or warm milk.

Contraindications

Vitamin nicotinic acid has minor contraindications. Generally, this drug is not recommended for use if:

individual intolerance to vitamin PP;
for acute liver diseases;
with liver failure;
with exacerbation of gastric ulcer;
with high blood pressure.

Also, nicotinic acid may have contraindications in a number of individual cases. Only a doctor can determine the advisability of using nicotinic acid in one form or another.

Electrophoresis for osteochondrosis

Prescribing electrophoresis with nicotinic acid for osteochondrosis helps to quickly remove accumulations of lactic acid from tissues affected by the inflammatory process. This reduces swelling and eliminates pain. Also, electrophoresis with nicotinic acid can ensure faster delivery of other medications to the affected area. This becomes possible due to the fact that blood flow increases and tissues are better supplied with oxygen and nutrients. Accordingly, the healing process goes much faster.

Most often, electrophoresis with nicotinic acid is prescribed once a day for ten days.

Effective treatment with nicotinic acid

To obtain the maximum effect, treatment with nicotinic acid should be started only after a complete examination of your health. The maximum effect is achieved only if a certain condition is associated with a lack of this vitamin in the human body.