The cheapest calcium tablets. Modern calcium preparations. Use in childhood

The article provides a list of popular calcium supplements, indicating prices and key features. Let's look at the main aspects that you need to pay attention to when choosing the best calcium supplement for yourself. Those who completely trust their intuition and are confident in the accuracy of their choice can safely go straight to the drug table.

Content:

A small educational program before choosing a calcium supplement

We won’t go into anatomy, we’ll just get to know what grows where and where. It will be easier to read the instructions for the drugs and understand why a certain aledronic acid is beating a certain osteoclast to death.

Bone consists of organic and inorganic parts. Organic is represented mainly by collagen fibers - ossein. Inorganic - from hydroxyapatite (a compound of calcium and phosphorus), inorganic magnesium salts and other elements. 98% of our calcium is concentrated in the bones.

Of the representatives of bone tissue cells, we will be interested in osteoblasts and osteoclasts. The function of osteoblasts is to create hydroxyapatites. The function of osteoblasts is to destroy them. The simultaneous activity of these cells ensures constant renewal of bone tissue. Thanks to this, the fabric retains its original properties and adapts to the needs of the body.

Weightlifters have higher bone mass and bone mineralization than the average person. A person who does not burden himself with regular physical activity will have the opposite situation.

What is not in demand in the body will gradually be put up for auction. And believe me, calcium, magnesium and phosphorus will scatter throughout the organs like hot cakes.

Taking this opportunity, I would like to express my gratitude to my skeleton for the support that he has provided me all this time.

Prevention of osteoporosis also involves regular physical activity. Create a load on the skeleton, show the body that you need a strong and durable frame. Without feasible physical exercise, there is little point in taking even the best and most effective calcium supplements. It is illogical to have a strong skeletal system that can withstand even the most unfortunate fall without fractures, when in everyday life you do not burden yourself with loads heavier than a backpack or bag.

What to look for when choosing a calcium supplement

Instructions for reading the instructions. A small educational program with emphasis to give a little idea of ​​what benefits we can get.

  1. Impact on osteoblasts and osteoclasts. Some create, others destroy. Normally, with adequate physical activity, these processes proceed at the same speed. In about 10 years, we will not meet a single familiar hydroxyapatite; we will be greeted by renewed generations, ready to endure and overcome stress with renewed vigor.

    In the description of calcium preparations, we can often encounter statements that some substance severely oppresses and inhibits osteoclasts, preventing them from carrying out their destructive activities. At the same time, it does not in any way affect the creative work of osteoblasts.

    It sounds good if you don’t focus on the disruption of bone tissue renewal processes. What if it happens that in 10 years we will not meet new generations of structural elements of bone, ready in orderly rows to perform their functions of support and protection. Before us will appear a shabby, seen a lot, “heavily used” a skeleton that has lost its former flexibility and elasticity.

  2. A list of macro- and microelements that it is desirable to see in the composition of the drug. So, we write down a shopping list for preparing the dish “ordinary human bone”: calcium, magnesium, phosphorus, vitamin D3 (cholecalciferol). Season all this generously with vitamins, proteins and garnish with physical activity to taste.
    If the body receives calcium and magnesium, but there is not enough phosphorus or vitamin D3, the incoming elements will be dispersed to other organs. Calcium and magnesium will not wait for tomorrow, when you add the missing ingredients to your body with breakfast. The dish will be spoiled, but the goodness will not be wasted - your heart or nervous system will thank you.
  3. Secret secret. If for some reason it is not possible to take a combination drug, then when choosing between calcium, magnesium, vitamin D3, choose magnesium. It plays a leading role in building bone mass.

  4. Direct effect on the functioning of parathyroid hormone (parathyroid hormone).
    We will not be mistaken if we assume that this substance is somehow connected with calcium metabolism in the body. Parathyroid hormone, among other things, controls the concentration of calcium in the blood, a vital sign. If the concentration drops, the hormone tries to return it to normal using all legal and not so legal means.

    This agent stimulates the activity of osteoclasts in order to destroy hydroxyapatites to obtain calcium. Stimulates the formation of the active form of vitamin D3, which increases calcium uptake in the gastrointestinal tract and reduces excretion by the kidneys. If there is insufficient intake of calcium from food, the skeletal system becomes the main source.

    Some drugs, as a bonus, inhibit the functioning of this hormone.

    The best way to prevent parathyroid hormone from becoming active is to provide the body with the right amount of calcium every day. This will ensure the maintenance of acid-base balance, adequate blood clotting, proper metabolism, hormone production, etc. Do not drive the body into a corner by leaving the skeletal system as the only source of calcium.

  5. Calcitriol, cholecalciferol, alfacalcidol, aledronic acid and other popular phraseological units from the bird's vocabulary, which can be found in the “composition” section.
    Calcitriol is the active form of vitamin D3. Active in regulating phosphate and calcium metabolism in the body. Plays the role of a conscientious caretaker, stores useful elements for a rainy day, increasing bone mass. Accordingly, in order to increase calcitriol, attention should be paid to drugs with cholecalciferol (vitamin D3).
    Alfacalcidol, an analogue of vitamin D3, has a less significant effect on the metabolism of phosphate and calcium, but has a superior effect on the activity of parathyroid hormone. It is valuable because it puts less strain on the kidneys and stays in the blood longer.
    Aledronic acid- a representative of bisphosphonates (this explains everything, yes). It is used in the prevention and treatment of osteoporosis, bone metastases, primary hyperparathyroidism and other diseases. Slows down the work of osteoclasts and promotes their destruction.

List of calcium preparations with prices and descriptions

Name Prices ($) Short description
Calcitriol
Rocaltrol (Switzerland / Hoffmann-La Roche) 8.83 — 21.98$ Calcitriol is a derivative of vitamin D3. It increases calcium absorption in the gastrointestinal tract. Reduces calcium loss through the kidneys.
Actively participates in the processes of bone tissue formation. Suppresses the secretion of parathyroid hormone.
Ossein-hydroxyapatite compound
Osteogenon (France / Pierre Fabre) 9.42 — 18.75$ The inorganic component of the drug contains calcium and phosphorus in the form of hydroxyapatite, which are necessary for the reconstruction of bone tissue.
The organic component (ossein) inhibits the work of cells that destroy bone tissue (osteoclasts) and stimulates the work of bone-forming cells (osteoblasts).
Alfacalcidol
Alpha D3‑Teva (Germany / Teva) 1.67 – 14.17$ The effect of the drug is due to the fact that it contains alfacalcidol, which is converted into calcitriol in the liver. Which in every possible way promotes the accumulation of calcium, increasing its supply and reducing the loss of the element.
Oksidevit (India / Panacea Biotek) 3.23 – 6.28$
Alfadol (Denmark / Leo Pharmaceutical Products) 6.55 – 9.82$
Alfacalcidol + calcium carbonate
Alfadol-Sa (India / Panacea Biotek) 4.8 — 10.52$ The effect of the calcitriol precursor is enhanced by the addition of an inorganic source of calcium in the form of carbonate.
Alfacalcidol + aledronic acid
Tevabon (Germany / Teva) 8.5 — 46.53$ Aledronic acid included in the composition inhibits the activity and causes self-destruction of osteoclasts, but does not increase the rate of bone tissue restoration.
Calcium chelate + magnesium + phosphorus + cholecalciferol
(USA/NSP) 20.52$ The composition contains chelated forms of calcium and magnesium, which increases the bioavailability of the elements. The elements are selected in the optimal ratio necessary for the restoration of bone tissue in the presence of vitamin D3. The formula is enhanced with a plant synergist - alfalfa.
Calcium carbonate + cholecalciferol (vitamin D3)
Natemille (Italy / Italfarmaco) 9.15 – 12.58$ Contains a source of calcium in the form of inorganic carbonate. Vitamin D3 controls calcium-phosphorus metabolism, increases the absorption and retention of calcium and phosphorus in the body.
Complivit Calcium-D3(Russia / Pharmstandard) 0.83 – 20.42$
Natekal D3 (Italy / Italfarmaco) 4.4 – 10.45$
Calcium-D3 Nycomed(~11 countries / Takeda) 2.67 — 15.32$
Calcium with vitamin D3 Vitrum(USA / Unipharm) 6 – 13.87$
Coral calcium + magnesium
(USA/NSP) 32.87$ It is a crushed powder made from corals that were mined from the sea near the Japanese Ryukyu Islands. Corals are 20-28% calcium and 10-14% magnesium. The resulting ratio of 2 to 1 is optimal for increasing bone mineralization. Among other things, it has pronounced alkalizing properties.
Calcium carbonate + calcium lactogluconate
Calcium – Sandoz forte(France / Novartis) 4.92 — 35$ Effervescent tablets provide an additional source of calcium in the form of two calcium salts: lactogluconate and carbonate. When the tablet dissolves, we get a drink with an orange scent.
Calcium carbonate + cholecalciferol + aledronic acid
Ostalon Calcium-D(Hungary / Gedeon Richter) 9.17 — 15.75$ The drug combines the properties of aledronic acid and vitamin D3. Their action is supported by inorganic calcium in the form of carbonate.
Preparations containing additional microelements
Vitrum Osteomag (USA / Unipharm) 5$ The basis of the drug is calcium carbonate and cholecalciferol. Added oxides of copper, zinc and magnesium, sodium borate, manganese sulfate. The addition of microelements improves the body's metabolic processes.
Osteokea (UK/Vitabiotics) 4.17 - 12.15$ Calcium carbonate, magnesium hydroxide, cholecalciferol. Also included is zinc in sulfate form
(USA/NSP) 28.60$ Vitamins D3, B12 and B6, C; calcium chelate, phosphate and citrate; chelate and magnesium oxide; phosphorus; zinc oxide; gluconates of iron, copper and potassium; manganese and boron chelates; betaine hydrochloride, beta-carotene.

Strengthening synergistic plants: cones and stems of horsetail, papaya fruit concentrate and pineapple juice, parsley leaves, licorice root extract and valerian.

Calcemin Advance(Bayer) 1.68 — 23.6$ There are Kalcemin and Kalcemin Advance. The Advance version has a higher content of substances, the addition of magnesium oxide and a higher cost. General: two calcium salts (carbonate and citrate), vitamin D3, copper and zinc oxides, sodium borate
Marine calcium biobalance(Russia/Ekomir) 68,5 — 110 The 5 varieties of this dietary supplement are characterized by a variety of composition variations. In the simplest version, the tablet contains calcium and vitamin C. The rest, in addition to these two substances, additionally include:
  • vitamin D3;
  • or zinc, magnesium, selenium;
  • or iodine;
  • or manganese, iron, copper.

Daily intake, indications for use and features of various forms of calcium

The daily calcium intake ranges from 800 to 1200 mg. Children, especially during periods of active growth, and women in the postmenopausal period need the maximum. With a normal diet, the average person receives 400 mg of calcium.

Indications for taking medications:

  • osteoporosis of any origin (postmenopausal, age-related, caused by hormonal therapy, immobilization, etc.);
  • used as a supplement in the treatment of osteomalacia and rickets;
  • with mild increased excitability of the neuromuscular system;
  • in cases where the need for calcium increases (pregnancy, breastfeeding, during periods of rapid growth in children, when playing sports);
  • as an addition to the treatment of allergic reactions;
  • decreased function of the parathyroid glands;
  • to improve the condition of hair, nails and skin;
  • prevention of pre- and postmenopausal bone demineralization in women;
  • during menopause.

Digestibility of various calcium compounds:

  • Inorganic forms are the worst absorbed. The bioavailability of such forms ranges from 10 to 20% according to various sources. Carbonate is most often found in tablets. One of the obvious advantages of such calcium supplements is that they are cheap.
  • Organic compounds. The bioavailability of such compounds is on average 2.5 times higher than that of carbonates. For example, for calcium chelate it exceeds 60%. The most common is citrate. For some, the higher price tag may spoil the impression of the higher effectiveness of such drugs.

A combined drug that regulates the exchange of calcium and phosphorus in the body (in bones, teeth, nails, hair, muscles).

Reduces resorption (resorption) and increases bone density, replenishing the lack of calcium and vitamin D 3 in the body, necessary for the mineralization of teeth.

Calcium is involved in the regulation of nerve conduction, muscle contractions and is a component of the blood coagulation system. Adequate calcium intake is especially important during growth, pregnancy and lactation.

Vitamin D 3 increases calcium absorption in the intestines.

The use of calcium and vitamin D 3 prevents an increase in the production of parathyroid hormone, which is a stimulator of increased bone resorption (leaching of calcium from the bones).

Pharmacokinetics

Suction

Typically, the amount of calcium that is absorbed from the gastrointestinal tract is approximately 30% of the dose taken.

Distribution and metabolism

99% of the calcium in the body is concentrated in the rigid structure of bones and teeth. The remaining 1% is found in intra- and extracellular fluids. About 50% of the total calcium content in the blood is in physiologically active ionized form, of which approximately 10% is complexed with citrate, phosphate or other anions, the remaining 40% is associated with proteins, primarily albumin.

Removal

Calcium is excreted through the intestines, kidneys and sweat glands. Renal excretion depends on glomerular filtration and tubular reabsorption of calcium.

Colecalciferol

Suction

Colecalciferol is easily absorbed from the small intestine (about 80% of the dose taken).

Distribution and metabolism

Colecalciferol and its metabolites circulate in the blood bound to a specific globulin. Colecalciferol is metabolized in the liver by hydroxylation to 25-hydroxycolecalciferol. It is then converted in the kidneys to the active form 1.25-hydroxycolecalciferol. 1.25-hydroxycolecalciferol is a metabolite responsible for increasing calcium absorption. Unchanged colecalciferol is deposited in adipose and muscle tissue.

Removal

Colecalciferol is excreted by the kidneys and intestines.

Release form

Chewable tablets (orange), uncoated, round, biconvex, white; with orange aroma; may have small inclusions and uneven edges.

Excipients: sorbitol - 390 mg, isomalt - 62.0 mg, povidone - 36.4 mg, magnesium stearate - 6.00 mg, aspartame - 1.00 mg, orange oil - 0.97 mg, mono- and diglycerides of fatty acids - 0.0008 mg.

20 pcs. - bottles made of high-density polyethylene (1) - cardboard packs.
50 pcs. - bottles made of high-density polyethylene (1) - cardboard packs.
100 pieces. - bottles made of high-density polyethylene (1) - cardboard packs.

Dosage

The tablets can be chewed or dissolved and taken with meals.

Calcium-D 3 Nycomed

Adults for the prevention of osteoporosis - 1 tablet. 2 times/day; in complex therapy of osteoporosis - 1 tablet. 2-3 times/day.

To replenish calcium and vitamin D deficiency, adults and children over 12 years old - 1 tablet. 2 times/day, children from 5 to 12 years old - 1-2 tablets/day, children from 3 to 5 years old - dosage in accordance with doctor's recommendations.

Calcium-D 3 Nycomed Forte

Adults for the prevention of osteoporosis - 1 tablet. 2 times/day or 2 tablets 1 time/day; in complex therapy of osteoporosis - 1 tablet. 2-3 times/day.

To compensate for calcium and vitamin D deficiency, adults and children over 12 years old - 2 tablets per day, children from 3 to 12 years old - 1 tablet per day or as prescribed by a doctor.

Duration of treatment

When used for prevention and in complex therapy of osteoporosis, the duration of treatment is determined by the doctor individually.

When used to replenish calcium and vitamin D 3 deficiency, the average duration of treatment is at least 4-6 weeks. The number of repeat courses during the year is determined individually.

Patients with impaired liver function do not require dose adjustment.

Should not be used in severe renal failure.

Elderly patients are prescribed the same dose as for adults. A possible decrease in creatinine clearance should be taken into account.

Overdose

Symptoms: manifestations of hypercalcemia - anorexia, thirst, polyuria, muscle weakness, nausea, vomiting, constipation, abdominal pain, fatigue, bone pain, mental disorders, nephrocalcinosis, urolithiasis and, in severe cases, cardiac arrhythmias. With long-term use of excessive doses (over 2500 mg of calcium) - kidney damage, soft tissue calcification.

If symptoms of overdose are detected, the patient should stop taking calcium and vitamin D, as well as thiazide diuretics and cardiac glycosides, and consult a doctor.

Treatment: gastric lavage, replenishment of fluid loss, use of “loop” diuretics (for example, furosemide), corticosteroids, calcitonin, bisphosphonates. It is necessary to monitor the content of electrolytes in the blood plasma, renal function and diuresis. In severe cases, measurement of central venous pressure and ECG monitoring are necessary.

Interaction

Hypercalcemia can potentiate the toxic effects of cardiac glycosides when used simultaneously with calcium and vitamin D preparations. Monitoring of ECG and serum calcium levels is necessary.

Calcium supplements may reduce the absorption of tetracyclines from the gastrointestinal tract. Therefore, tetracycline drugs should be taken at least 2 hours before or 4-6 hours after taking the drug.

To prevent decreased absorption of bisphosphonate drugs, it is recommended to take them at least 1 hour before taking Calcium-D 3 Nycomed.

GCS reduce calcium absorption, so treatment with GCS may require an increase in the dose of Calcium-D 3 Nycomed.

With simultaneous use of thiazide diuretics, the risk of hypercalcemia increases, because they increase tubular reabsorption of calcium. When thiazide diuretics are used concomitantly, serum calcium levels should be regularly monitored.

Calcium reduces the effectiveness of levothyroxine by reducing its absorption. The period of time between doses of levothyroxine and Calcium-D 3 Nycomed should be at least 4 hours.

The absorption of quinolone antibiotics is reduced when used simultaneously with calcium supplements. Therefore, quinolone antibiotics should be taken 2 hours before or 6 hours after taking Calcium-D 3 Nycomed.

Eating foods containing oxalates (sorrel, rhubarb, spinach) and phytin (cereals) reduces the absorption of calcium, so you should not take Calcium-D 3 Nycomed within 2 hours after eating sorrel, rhubarb, spinach, cereals.

Side effects

The frequency of side effects of the drug is assessed as follows: very frequent (>1/10); frequent (>1/100,<1/10); нечастые (>1/1000, <1/100); редкие (>1/10 000, <1/1000); очень редкие (<1/10 000).

Metabolism and nutrition: uncommon - hypercalcemia, hypercalciuria.

From the digestive system: rarely - constipation, flatulence, nausea, abdominal pain, diarrhea, dyspepsia.

From the skin and subcutaneous tissue: very rarely - itching, rash, urticaria.

Indications

  • prevention and treatment of calcium and/or vitamin D 3 deficiency;
  • prevention and complex therapy of osteoporosis and its complications (bone fractures).

Contraindications

  • hypercalcemia;
  • hypercalciuria;
  • nephrolithiasis;
  • hypervitaminosis D;
  • severe renal failure;
  • active form of tuberculosis;
  • sarcoidosis;
  • hypersensitivity to the components of the drug, soy or peanuts.

The drug in tablet form is not used in children under 3 years of age.

The drug contains sorbitol, isomalt and sucrose, so its use is not recommended for patients with hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency.

With caution: pregnancy, lactation, renal failure.

Features of application

Use during pregnancy and breastfeeding

Calcium and vitamin D 3 are used during pregnancy to compensate for their deficiency in the body.

During pregnancy, the daily dose of the drug should not exceed 1500 mg of calcium and 600 IU of vitamin D 3 .

Hypercalcemia due to overdose during pregnancy can have an adverse effect on the developing fetus.

The drug is used during lactation.

Calcium and vitamin D 3 can pass into breast milk, so it is necessary to consider the intake of calcium and vitamin D from other sources in the mother and baby.

Use for renal impairment

The drug is contraindicated in severe renal failure.

Use in children

The dosage form of the tablet is not used in children under 3 years of age.

special instructions

During long-term therapy, serum calcium and creatinine levels should be monitored. Monitoring is especially important in elderly patients during concomitant treatment with cardiac glycosides and diuretics and in patients with an increased tendency to form kidney stones. In cases of hypercalcemia or signs of renal impairment, reduce the dose or discontinue treatment.

Vitamin D should be taken with caution in patients with renal failure. In this case, it is necessary to monitor the calcium and phosphate levels in the blood serum. The risk of soft tissue calcification must also be considered.

To avoid overdose, additional vitamin D intake from other sources must be taken into account.

Calcium and vitamin D 3 should be used with caution in immobilized patients with osteoporosis due to the risk of developing hypercalcemia.

Concomitant use with tetracycline or quinolone antibiotics is usually not recommended or should be done with caution.

Impact on the ability to drive vehicles and operate machinery

The drug does not affect the ability to drive vehicles or operate complex machinery.

Calcium and phosphorus are an integral part of the human body. The optimal balance of these substances is the key to strong bones and muscles, beautiful hair and strong nails. The modern drug Calcium-D3 Nycomed helps maintain the required level of vitamin D and calcium.

The drug is available in the form of fruit-flavored tablets. For this tasty and healthy pleasure you will have to pay a very substantial amount. If you don’t have the desire or ability to pay a lot of money for a drug, then you can pay attention to analogues that are more affordable and no less effective.

Calcium-D3 Nycomed: purpose and contraindications

Compound

The composition is based on calcium carbonate and vitamin D. The drug is also supplemented with auxiliary components - povidone, sorbitol, magnesium stearate, aspartame and fruit flavorings.

Indications

Prescribed as a prophylaxis, as well as therapeutic therapy for vitamin D and calcium deficiency. Besides, is the basis for the treatment of osteoporosis of any stage.

Contraindications

In addition, Calcium-D3 Nycomed is prohibited from taking in case of renal and liver failure, tuberculosis and in young patients under three years of age.

Side effects

Any medication can cause side effects. This also applies to Calcium-D3 Nycomed. Side effects are expressed in the following symptoms:

  • nausea;
  • discomfort, pain in the abdominal area;
  • flatulence;
  • bowel dysfunction (constipation or vice versa diarrhea);
  • development of an allergic reaction.

If the dosage is incorrectly selected or the drug is prescribed incorrectly, There may be an excess of calcium and vitamin D in the body.

Price

The price depends on the number of tablets in the package:

  • a package containing 30 tablets - the cost is within 250 rubles;
  • a package containing 50 tablets can be purchased for an average of 370 rubles;
  • for 100 tablets you will have to pay approximately 520 rubles.

The tablets are presented in an interesting chewable form and have different fruit flavors. The cost per package may vary depending on the taste.

Analogues of the drug

Pharmacies offer a wide selection of various medications. If there is a lack of calcium and vitamins in the body, you can, with the help of an experienced doctor, select a set of medications that replenish the deficiency of these substances. You can also find vitamin complexes that have a less aggressive effect on the body.

The main advantage of analogues is their more affordable cost. So, what can you replace Calcium-D3 Nycomed with? Several cheap analogues are comparable to the drug, including in price.

Take calcium plus D3

This drug is considered an analogue of Calcium D3 Nycomed Forte, due to the same amount of vitamin D in the tablet.

Compound. The basis of the drug is iron oxide, vitamin D and calcium carbonate. In addition, it is supplemented with auxiliary components that enhance the properties of the drug. These include: soy, talc and corn starch.

Indications. Used for the prevention and treatment of vitamin D and calcium deficiency, as well as for the treatment of osteoporosis.

Contraindications. The drug should not be taken for a number of diseases. These include:

  • urolithiasis disease;
  • thyroid dysfunction;
  • renal failure;
  • oncological neoplasms (both malignant and benign forms).

Contraindications also include individual intolerance or hypersensitivity to the components of the drug.

Price. The average cost for a package of tablets is around 200 rubles.

Comparison with the original. The analogue is certainly more attractive in cost, but in terms of the quality of the composition inferior to the original in the presence of auxiliary components, very strongly diluting the pure composition Calcium-D3 Nycomed. In addition, this cheaper analogue has a wider range of contraindications.

Vitrum Calcium

Compound. A vitamin complex based on calcium and vitamin D. It also contains a rich mineral base.

Indications. The drug is used as an effective prevention of calcium and vitamin D deficiency in the human body, and also helps prevent the development of osteoporosis.

In complex therapy it is used to treat various stages of osteoporosis. Can be used to treat children from the age of eight.

Contraindications. The vitamin complex has a number of contraindications for which its use is strictly prohibited. These include:

  • individual hypersensitivity or absolute intolerance to the components of the drug;
  • oncological diseases of benign and malignant nature;
  • excess calcium in the body;
  • tuberculosis;
  • renal failure.

Side effects. Taking the drug can cause severe abdominal discomfort, characterized by: nausea, constipation or diarrhea, colic, pain.

Price. The price for a package of tablets is on average 220 rubles.

Comparison with the original. The analogue is much cheaper than Calcium D3 Nycomed, however high content of mineral base can cause hypercalcemia.

Calcium-active

Compound. Calcium-active is not a complete medicinal product, since belongs to the group of biologically active additives (BAS). The basis of the drug is calcium and cholecalciferol.

Indications. Prescribed for the prevention of calcium deficiency in the human body, as well as for the treatment of osteoporosis.

Contraindications. The dietary supplement is quite well tolerated. Contraindications include only hypersensitivity to the components of the drug or their absolute intolerance.

Price. The maximum cost in Russian pharmacies for a package of tablets does not exceed 150 rubles.

Comparison with the original. The main advantage of the analogue is low cost. If you need to slightly correct the level of calcium in the body, then this drug will cope with this role, but will require long-term use due to the small content of active substances in one tablet (50 milligrams of calcium).

If you need more urgent and high-quality help for the body, then you will have to give preference to the original, the composition of which is richer in calcium and vitamin D.

All of the above medications can be used during pregnancy and breastfeeding (certainly after consultation with your doctor!) to prevent calcium deficiency.

According to reviews, Calcium-D3 Nycomed is currently one of the most popular drugs for the prevention and treatment of calcium deficiency. However, in some cases, an advertised and expensive remedy is not always the only way to excellent health.

Whatever the final choice, you must remember that it is strictly not recommended to take any medication as self-medication! Consultation with your doctor is mandatory. Even at first glance, the safest drug can cause serious harm to the body, due to individual characteristics of human health.

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Composition of 1 chewable tablet:

  • – 1250 mg (in terms of elemental calcium – 500 mg);
  • cholecalciferol – 5.0 mcg, which corresponds to 200 international units;
  • – 390 mg;
  • isomalt – 62.0 mg;
  • povidone – 36.4 mg;
  • Magnesium stearate – 6.00 mg;
  • – 1.0 mg;
  • orange oil in the amount of 0.97 mg or mint flavoring weighing 31.9 mg;
  • mono and diglycerides of fatty acids – 0.0008 mg.

Compound Calcium D3 Nycomed Forte(1 chewable tablet):

  • calcium carbonate – 1250 mg (equivalent to 500 mg of elemental calcium);
  • vitamin D3 (cholecalciferol) – 10 mcg (400 IU);
  • sorbitol – 390 mg;
  • isomalt – 49.9 mg;
  • povidone – 36.4 mg;
  • Magnesium stearate – 6 mg;
  • aspartame – 1.0 mg;
  • lemon oil – 0.78 mg;
  • mono and diglycerides of fatty acids – 0.0006 mg.

Release form

  • Orange or mint chewable tablets Calcium D3 Nycomed white, without a shell, biconvex, round in shape with a corresponding aroma. Small dotted inclusions and uneven edges are allowed. Tablets are packaged in high-density polyethylene bottles of 20,50 or 100 pieces. The cardboard package contains 1 bottle of medicine and an annotation for the drug.
  • Calcium Nycomed D3 Forte– round chewable tablets with lemon flavor. The biconvex tablets are uncoated and are sold in high-density polyethylene bottles of 30, 60 and 120 pieces. A cardboard box contains 1 bottle and instructions for use of the drug.

pharmachologic effect

The drug refers to combined pharmaceutical preparations that regulate the metabolism of calcium and phosphorus in the body and compensate for the deficiency of the main structural element. The biochemical role of calcium lies in the physiological construction of bone tissue, mineralization of teeth, the processes of coagulation and transmission of nerve impulses, and the implementation of muscle contractions. In response to its increase in the systemic circulation, bone tissue density increases and calcium excretion by the kidneys decreases.

Cholecalciferol is responsible for the processes of absorption of the element in the gastrointestinal tract and its distribution in the body. Oral administration of the drug inhibits synthesis parathyroid hormone – a natural hormone of the parathyroid gland, which significantly affects phosphorus-calcium metabolism. Accordingly, the amount of calcium absorbed from the digestive tube increases and its resorption (leaching) from bones and other organs decreases.

Pharmacodynamics and pharmacokinetics

Calcium is absorbed from the proximal part of the digestive tube in the amount of 30% of the dose taken, after which the element enters the systemic bloodstream, where 50% is in active ionized form, that is, the active substance binds to citrates, phosphates, and some other anions and protein structures. The main building component is eliminated by the intestines, sweat glands and kidneys. When calculating excretion, it should be taken into account that renal excretion of calcium depends not only on glomerular filtration, but also on tubular reabsorption.

Vitamin D3 is absorbed predominantly from the small intestine, from where about 80% of the dose taken enters the main bloodstream, where it binds to specific transport globulin. The metabolism of cholecalciferol includes two stages - first, the vitamin is converted into 25-hydroxycholecalciferol by hydroxylation, after which, upon reaching the kidneys, it is transformed into the active form - 1,25-hydroxycholecalciferol . The unchanged vitamin is stored by the body in muscle and fat tissue. Cholecalciferol is excreted through the urine and intestines.

Indications for use

  • prevention and comprehensive treatment ;
  • calcium and/or vitamin D3 deficiency;
  • bone fractures.

Contraindications

Absolute contraindications to the use of the pharmaceutical drug:

  • hypervitaminosis D;
  • hypercalcemia – increased calcium in the blood;
  • hereditary fructose intolerance;
  • immobilized patients;
  • hypercalciuria – the appearance of calcium in the urine;
  • glucose-galactose malabsorption;
  • nephrolithiasis and other diseases in the pathogenesis of which the formation of calcium stones is noted;
  • active form ;
  • sucrose-isomaltase deficiency;
  • increased sensitivity to the constituent components of a medicinal product or to food products such as soy and peanuts;
  • children under 3 years of age.

Side effects

  • From the outside metabolism: hypercalcemia and hypercalciuria.
  • From the outside gastrointestinal tract: (constipation ), flatulence , , nausea , abdominal pain , .
  • From the outside skin and subcutaneous tissue: rash , , .

Instructions for Calcium D3 Nycomed (Method and dosage)

The instructions for use of the pharmaceutical product indicate that the drug is used orally, and the tablets should be chewed or dissolved during meals. For prevention osteoporosis The dosage of Calcium D3 Nycomed is used: 1 tablet 2 times a day or 2 tablets 1 time a day. With the aim of complex therapy for this pathological condition, take 1 tablet of Ca D3 Nycomed 3 times a day. The duration of such treatment is prescribed individually, based on biochemical indicators of metabolic processes and the condition of bone tissue, teeth and skin derivatives (hair and nails).

For liquidation deficiency states The duration of the course of treatment is at least 4-6 weeks, and the dosage must take into account the age category of the patient:

  • children from 3 to 5 years old – 1 or ½ tablets per day;
  • from 5 to 12 years – 1-2 tablets per day;
  • adults and adolescents over 12 years old – 1 tablet 2 times a day.

The instructions for Calcium D3 Nycomed Forte differ only in the dosage of the drug and the duration of the course of conservative therapy, therefore, when prescribing it, these aspects of drug correction of phosphorus-calcium metabolism should be additionally discussed with the attending physician.

Overdose

In case of an overdose of a pharmaceutical drug, symptoms develop that indicate hypercalcemia :

  • anorexia ;
  • dry mouth, thirst;
  • muscle weakness;
  • nausea and other dyspeptic disorders;
  • polyuria ;
  • bone pain;
  • mental disorders;
  • nephrocalcinosis ;
  • (with a prolonged increase in blood calcium concentration);
  • (in especially severe cases);
  • soft tissue calcification;
  • organic kidney damage.

If symptoms of excess are detected calcium And vitamin D3 you should immediately stop taking the pharmaceutical drug, Tiazide diuretics And cardiac glycosides (features of the pharmacokinetics of therapeutic properties are indicated in the “Interactions” section) and consult your doctor. As a rule, “loop” diuretics are prescribed for therapeutic purposes (the drug of choice is ), oral glucocorticosteroids, , bisphosphonates. In case of overdose, it is necessary to monitor the following physiological indicators:

  • content of electrolytes in blood plasma;
  • renal function and diuresis;
  • central venous pressure;
  • electrical activity of the heart.

Interaction

When used in combination with Calcium D3 Nycomed and cardiac glycosides Potentiation of the toxic effect of the latter is possible, therefore, if their simultaneous use is necessary, careful monitoring of electrocardiography and calcium concentration in the blood is recommended.

Calcium may reduce absorption capacity groups quinoline And row , and , bisphosphonates Therefore, these drugs should be taken no earlier than 2 hours before or 6 hours after using medications based on the physiological “builder” of the body’s skeletal system.

Glucocorticosteroids , barbiturates ,laxatives , phenytoin And reduce the bioavailability of an oral therapeutic agent, that is, the active components are absorbed in the gastrointestinal tract in smaller quantities, therefore it is necessary to adjust the dosage or regimen of Calcium D3 Nycomed during conservative treatment, which involves combining the drug with other pharmaceutical products.

Thiazide diuretics in pharmacy they are sometimes called saving drugs, since pharmaceutical drugs of this series inhibit the tubular reabsorption of calcium and some other micro- and macroelements, as a result of which regular monitoring of calcium in the blood serum is required to avoid hypercalcemia and overdose.

Use food products , which contain oxalates (sorrel, potatoes, spinach, rhubarb) or (most crumbly cereals), reduces the ability of calcium to be absorbed in the gastrointestinal tract, so the daily diet should be adjusted in a special way. You should not take the pharmaceutical drug within four hours of eating any of the foods listed above.

Terms of sale

The sale of a pharmaceutical drug involves over-the-counter dispensing at pharmacy kiosks.

Storage conditions

The medicine should be stored in a tightly closed bottle in a dry place out of the reach of children. Temperature regime – no higher than 25 degrees Celsius.

Best before date

special instructions

Brief information about the manufacturer

Nycomed is a Swiss pharmaceutical company founded back in 1874 with headquarters in Zurich, and is widely known for its medicinal products such as, And Calcium D3 . Until a certain time, it was one of the 30 largest corporations in the world in terms of sales volume in the market of conservative therapeutic agents. In September 2011, it was purchased by a Japanese company Takeda, one of whose areas of interest is metabolic diseases and their correction through drug treatment. Therefore, the official Nycomed website is now represented by an Internet resource managed by Takeda.

The impact of a pharmaceutical drug on areas of daily life

Calcium D3 Nycomed is a combination drug with a designated selectivity of therapeutic action, that is, the active components of chewable tablets and their auxiliary components do not affect the ability to concentrate, long-term attention, or other areas of everyday life. During the course of treatment, independent driving of vehicles and work with technical complex mechanisms is allowed.

Analogues of Calcium D3 Nycomed

Level 4 ATX code matches:

The drug belongs to the group of combined drugs for regulating calcium levels in the blood and the content of a structural element in the tissues of the body. Of course, there are various analogues of chewable tablets. As a rule, drugs are presented directly with a biogenic component and excipients for a more complete realization of its therapeutic properties. So it should be noted:

  • - predominantly used for children to prevent calcium deficiency;
  • Ideos - chewable tablets prescribed for senile, age-related osteoporosis or its occurrence due to menopause;
  • - used for idiopathic progressive calcium deficiency and its complications in the form of bone fractures or dental problems.

These drugs are prescribed if there are any absolute or relative contraindications to Calcium D3 Nycomed, for example, with increased sensitivity to its auxiliary components, in order to avoid or the development of adverse consequences of conservative therapy. The price of analogues of Calcium D3 Nycomed is usually higher, which gives a clear advantage to this pharmaceutical agent for the correction of phosphorus-calcium metabolism.

Calcemin or Calcium D3 Nycomed - which is better?

is one of the most popular analogues of Calcium D3 Nycomed. This is a combination pharmaceutical preparation, the composition of which includes calcium carbonate , vitamin D3 , copper and zinc oxide, manganese sulfate and sodium borate. Film-coated tablets are prescribed not only for disorders of phosphorus-calcium metabolism, but also to compensate for the deficiency of certain microelements , which have important biological significance for the normal functioning of the body.

Calcium dosage and cholecalciferol in Calcemin is an order of magnitude less than in chewable tablets Calcium D3 Nycomed, which leads to fewer side effects and a sharply reduced chance of overdose. But the composition of the drug also determines more long-term medication course therapy for, therefore it is prescribed mainly for adolescent children and women during pregnancy or lactation. Calcium D3 Nycomed, in turn, copes much more effectively with its main task - regulating phosphorus-calcium metabolism and eliminating related complications.

Calcium D3 Nycomed for children

In childhood, progressive metabolic diseases are especially difficult to tolerate, because the young body is still at the development stage and the stock of compensatory and adaptive mechanisms has not yet been fully formed. Deficiency of calcium and vitamin D is one of the most pressing problems described by pediatric orthopedics, because as a result of this pathological deficiency a large number of severe nosological units can be formed, up to mental and physical development delays Therefore, it is so important to undergo regular medical examinations and promptly correct all diagnosed disorders.

How to take Calcium D3 Nycomed for children should be found out exactly from the treating pediatrician, because its dosage is selected individually taking into account the current level of blood calcium, concentration parathyroid hormone and some other biochemical indicators.

The standard regimen of conservative therapy involves prescribing 1 tablet 1-2 times a day from 5 to 12 years of age, and for adolescents over 12 years of age - 1 chewable tablet 1-3 times a day. It should be understood that an excess of a pharmaceutical drug, as well as its deficiency, can lead to the adverse effects described in the “Overdose” section.

With alcohol

Alcohol abuse is a common cause deficiency states , since alcohol promotes the leaching of micro- and macroelements, as well as vitamin structures from tissues and organs, therefore bad habits should be completely eliminated during the period of undergoing a conservative course of treatment with chewable calcium-based tablets. As a preventive measure, it is recommended to significantly limit the amount of alcoholic beverages, caffeine and smoking in the future.

Calcium D3 Nycomed during pregnancy and lactation

Insufficiency of micro- and macroelements for pregnant women is a common condition, because the woman’s body provides not only its own needs, but also supplies the necessary structural “building blocks” for the normal organization of the child’s tissues and organs. Especially often manifested calcium deficiency - one of the main components of the skeleton, muscular organs and nervous system, however, it is quite difficult to digest, therefore the use of special drugs that compensate for the state of deficiency is recommended. Medicines are prescribed if the following symptoms of calcium deficiency are observed during pregnancy:

  • back pain;
  • numbness of the upper and lower extremities;
  • hair loss and brittle nails;
  • tooth decay;
  • leg cramps.

Calcium D3 Nycomed during pregnancy is the drug of choice to compensate for the deficiency of a structural element in the mother’s body. First of all, the drug allows you to eliminate calcium deficiency in a relatively short time and restore pathologically altered body functions. It should also be noted that the oral form of using chewable tablets is more physiological and to a lesser extent can cause any side effects or adverse consequences for the woman and her unborn child.

Calcium D3 Nycomed tablets can also be used for breastfeeding , however, it should be taken into account that the active components of the pharmaceutical drug have the ability to penetrate into breast milk during lactation, and therefore it is necessary to accurately correlate other sources of calcium and vitamin D into the newborn’s body. When prescribing Calcium D3 Nycomed to a young mother, you should definitely find out the symptoms hypervitaminosis And hypercalcemia in a small child, in order to stop using the drug in time.

Calcium is a very important element for the proper functioning of certain systems of the human body. Since childhood, grandmothers and mothers have said that you must eat cottage cheese and eggs to keep your bones strong and to grow faster. In addition, a lack of calcium negatively affects a person’s appearance. The skin becomes dull, the hair loses its vital shine, and the nails break. To compensate for the lack of this element in the body, you can purchase a specialized drug at the pharmacy - “Calcium D3 Nycomed Forte”. It’s also not at all difficult to find cheaper analogues.

Brief description of the drug

It is a combined product with a high content of calcium and vitamin D3. Designed to compensate for the lack of these two elements in the body. Available in the form of chewable tablets with orange, menthol and lemon flavors.

pharmachologic effect

The effect of taking Calcium D3 Nycomed (cheaper analogues also work) is determined by the content of active components in it. Once in the human body, these substances, in addition to replenishing the deficiency of elements, regulate the exchange of phosphates with Ca, increase bone density, reduce resorption and promote bone mineralization. Thanks to calcium, the absorption of substances in the intestine improves. What is also important is that the Ca element is involved in processes that are extremely necessary for human life:

  • blood clotting;
  • bone tissue formation;
  • regulation of the cardiovascular system;
  • transmission of nerve impulses.

You may be interested in the question - why is it contained in the drug? The fact is that many substances cannot independently spread through organs and tissues and be absorbed. Calcium also has this feature, so D3 comes to its aid. When paired, the elements suppress the production of parathyroid hormone in the body, which causes bone destruction.

Indications and contraindications

Like the analogue “Calcium D3 Nycomed” (cheaper in cost compared to this drug), it should not be taken if you are hypersensitive to the components of the drug (including peanuts and soy), as well as with Other contraindications:

  • renal failure;
  • increased calcium content in the body;
  • active tuberculosis;
  • hypercalciuria;
  • fructose intolerance;
  • sarcoidosis;
  • nephrolithiasis;
  • children under five years of age.

The drug is indicated for the prevention of calcium and vitamin D3 deficiency and replenishment of the deficiency of substances, as well as in the complex therapy of osteoporosis and to prevent the development of complications of this disease.

"Calcium D3 Nycomed" - cheaper analogues

The average cost of the drug is 430 rubles. It depends on the number of tablets in the jar. But there are situations when a similar drug may be required not because of the relatively high price, but, for example, due to intolerance to the components included in the composition. The simplest thing you can do in this case is to purchase calcium and vitamin D3 separately, but take them together. It’s just better not to experiment and consult a doctor.

Another analogue is “Calcid”. The price for it fluctuates around 50 rubles. A little more expensive (130 rubles) “Complivit calcium D3”. These two drugs are no worse, but it is important not to forget to ask your doctor for advice.

Almost all girls in an “interesting” position lack calcium. Some will probably remember how much they wanted to chew chalk during this period. “Calcium D3 Nycomed” analogues are cheaper for pregnant women and are the same as those written above. The tablets should be taken strictly according to the instructions, not exceeding the dosage indicated in the annotation, or the one recommended by the gynecologist or therapist.

"Calcium D3 Nycomed" (cheaper analogues) - reviews

Opinions about this drug differ: some write that it has helped a lot in getting rid of brittle nails and hair loss, others have a negative attitude towards the product, considering its use pointless. The same reviews come from pregnant women; in addition, some gynecologists refuse to prescribe it to pregnant girls, as they do not notice any effectiveness.