Mexidol tablets: instructions for use. The drug Mexidol, its effect on blood pressure and the body as a whole

Mexidol (in Latin Mexidol) is a drug created on the basis of ethylmethylhydroxypyrine. The substance acts as a protector of cell membranes from the harmful effects of free radicals. It is used to treat a large number of mental pathologies.

Release form, composition and packaging

Available in the form of injections and tablets.

1. The tablets contain 125 mg of ethylmethylhydroxypyridine succinate (2-ethyl-6-methyl-3-hydroxypyridine succinate). Lactose monohydrate and magnesium stearates are added as filling components. The tablets are coated with a coating of different shades.

The use of drugs for veterinary medicine is not allowed.

There is Mexidol-dent toothpaste. It has nothing to do with the medicine.

pharmachologic effect

1. Increases the resistance of body cells to shock factors, oxygen starvation and a decrease in the volume of blood circulating in the bloodstream. Indicated for acute and chronic poisoning with ethanol-containing drinks, especially surrogates.
2. The medicine slows down the processes of fat oxidation and increases the activity of superoxide dismutase. Reduces the viscosity of the cell membrane substance and increases its fluidity.
3. The drug increases blood transport in the brain. Improves microcirculation processes, reduces platelet aggregation processes. Normalizes cell membrane structures. Reduces total cholesterol levels, especially low-density cholesterol.
4. The anti-stress effect of the drug is manifested in the regulation of post-stress function of the central nervous system. Combats somatovegetative disorders, restores the normal frequency of sleep and wakefulness cycles. Affects the processes of attention and memory impairment. Reduces the intensity of degenerative lesions in the membranes of the brain.
5. The drug effectively eliminates the consequences of alcohol intoxication. Acts as an antidote for alcohol withdrawal syndrome. Helps relieve cognitive impairment associated with prolonged alcohol consumption.
6. Improves the condition of the heart muscle after ischemia, i.e. acute disruption of its nutritional processes. Helps improve the condition of heart muscle cells. Increases blood pressure in some patients.
7. Under the influence of the drug, the action of tranquilizers, antipsychotics, antidepressants and anticonvulsants is activated.

Pharmacokinetics allows you to effectively achieve the desired therapeutic result. It is quickly absorbed into the blood when taken internally. Well distributed in cells and tissues. It is retained in the body for 5 hours, disintegrates in the liver with the synthesis of several types of metabolites - decomposition products.

It is excreted from the body in the urine almost completely in the form of metabolic products and only in small quantities unchanged. The most intensive elimination of the drug occurs within approximately 4 hours after ingestion. Concentrations in unchanged form and in the form of metabolites vary depending on individual characteristics.

Analogs

Analogues of this drug are:

• Cavinton;
• Mexiprim.

ATX

ATX code - N07XX. Refers to other medications for the treatment of pathologies of the nervous system.

What is Mexidol needed for?

Indications for the use of Mexidol in adults are as follows:

• cerebral circulatory dysfunctions and their consequences;
• ischemic attacks;
• prevention of acute circulatory disorders in the myocardium;
• hypertension (decompensation phase);
• traumatic brain injuries and their consequences;
• brain damage of various causes, encephalopathy;
• vegetative-vascular dysfunction;
• brain disorders of atherosclerotic origin;
• anxiety disorders;
• neurosis-like pathological conditions;
• mixed therapy for ischemic heart disease;
• withdrawal syndrome in alcoholism (the need to relieve it);
• post-withdrawal nervous and autonomic disorders;
• acute intoxication as a result of taking tranquilizers and other similar drugs;
• asthenia;
• pain with cervical osteochondrosis;
• prevention of neuroses when exposed to extreme environmental factors, prolonged and intense emotional overload;
• intense mental stress;
• heavy physical activity.

How and how much to take

There are some differences in the method of taking pills and injections.

Pills

Use 0.125 - 0.25 g orally, 3 times a day. The highest dose is 0.75 g, that is, 6 tablets. The duration of therapy is from 2 to 6 weeks. Discontinuation of treatment occurs gradually with a reduction in dose. For the treatment of alcohol withdrawal syndrome, the duration of therapeutic measures is up to 7 days.

In the first days, the dose is 0.125 or 0.25 g 1 or 2 times a day. Then it rises to the maximum.

Solution

Injections must be given intravenously or intramuscularly. In the first 5 days, intravenous administration of 1 ampoule of the drug is recommended. In severe cases, 2 ml of solution is indicated. Subsequently, they switch to intramuscular injections.

With intravenous injections, the medicine is introduced into the body gradually to prevent side effects. If necessary, a drip is prescribed. The frequency of administration of the solution is every 8 hours. The daily therapeutic dose is from 6 to 9 mg per kilogram of weight, and a single dose is from 2 to 3 mg.

In case of acute disruption of cerebral blood supply, drip administration of the solution is used 2 times a day, 200 - 300 mg (diluted in an isotonic solution of sodium chloride). In the future, the drug must be prescribed intravenously. The duration of such therapy is on average 2 weeks.

For brain disorders, the treatment regimen is the same, but at a dose of 100 mg per time.

For cognitive disorders, intramuscular injections of the drug are prescribed from 100 to 300 mg 3 times a day. Duration of therapy is 2 weeks. In the future, the patient is recommended to take capsules.

Before or after meals

In the morning or evening

The medicine is prescribed in the morning, afternoon and evening.

special instructions

It has numerous features of use in different categories of patients.

Use of the drug during pregnancy and lactation

It is prohibited to use for the treatment of neurological pathologies in pregnant and lactating women due to insufficient experience of use in these categories of patients. Although there has been no data on the toxic effects of the active substance of the drug, you should not take risks and prescribe the drug while pregnant.

It can penetrate into breast milk, causing disruption of the nervous system in the fetus. Therefore, the use of Mexidol for nursing mothers is strictly prohibited. If during this time it is necessary to be treated with these tablets and injections, then the child is transferred to artificial feeding.

Use in children

It is prohibited to use the product for the treatment of pathologies of the nervous system in children. There is no data on the use of Mexidol in persons under 18 years of age. May exhibit toxicity.

Use for renal impairment

Particular caution should be taken when prescribing the medication to patients with severe renal dysfunction. The dosage of the medicine is selected in such cases strictly individually. The use of the drug is not recommended for persons on hemodialysis.

Use for liver dysfunction

In case of cirrhosis and liver dysfunction, the drug is contraindicated. If the patient has mild liver disorders, the medicine is prescribed with caution, with an individually selected dosage.

Mexidol and alcohol

Although the medication is prescribed to combat alcohol addiction, drinking alcohol during therapy is strictly prohibited. The medicine is not able to protect the body from the harmful effects of ethanol.

Taking the drug and alcohol at the same time increases side effects and makes a person’s behavior unpredictable.

Impact on the ability to drive vehicles and complex mechanisms

During treatment, you should be careful when working with mechanisms of increased complexity and precision. To avoid road accidents, it is better not to drive a car, because the medication can slow down the reaction rate.

Contraindications to the use of Mexidol

The drug is prohibited for:

• individual hypersensitivity to the substances included in the composition;
• acute liver and kidney failure;
• childhood;
• expecting a child;
• lactation.

Side effects

With intravenous and drip use, a metallic taste may appear in the mouth. Other side effects:

• feeling of heat in the body;
• the appearance of unpleasant body odor;
• burning throat and foreign body illusion;
• feeling of soreness in the chest;
• dyspnea;
• headaches and pain in the face;
• increased heart rate;
• blood pressure surges;
• trembling of limbs;
• facial redness;
• increased sweating.

These phenomena are short-term and disappear without additional treatment.

With prolonged use of the drug, the following side effects are possible:

• nausea;
• increased formation of intestinal gases;
• dyspepsia;
• diarrhea;
• symptoms of abdominal diseases associated with pain;
• drowsiness or difficulty falling asleep;
• severe weakness;
• anxiety;
• violation of coordination of movements;
• syncope;
• swelling;
• allergic reactions manifested in Quincke's edema, skin rashes, urticaria, angioedema, bronchospasm.

Mexidol overdose

In case of overdose, signs of sleep disturbance appear. In some cases, there may be daytime sleepiness. When administered intravenously, a short-term increase in blood pressure sometimes occurs.

The development of overdose manifestations does not require additional relief. Sleep disorders resolve without concomitant treatment. If blood pressure increases, antihypertensive drugs are prescribed.

Possible side effects: sleep disorders - insomnia/drowsiness...

Mexidol is an original Russian-made drug.

Mexidol produces significant anti-alcohol effect, has geroprotective(corrects processes characteristic of aging of the body) And antiatherogenic(prevents the occurrence of pathological changes in blood vessels and the aorta) action.

However, like any chemical drug, Mexidol has side effects on the body and has contraindications for its use.

What side effects does Mexidol have on the body?

Fortunately, the drug itself is characterized by low toxicity; There are few side effects from its use. Experiments on animals have shown that even when using the maximum permissible therapeutic doses of Mexidol, no significant side effects occur.

In treatment, it is very important that the medication does not have a negative effect on the liver. And Mexidol has this property. Moreover, the drug has a hepatoprotective effect (protects the liver).

Maybe, Does Mexidol change heart rate, electrocardiogram, blood pressure (BP), hemodynamics? The answer is negative!

Experiments on animals have shown that Mexidol also has no effect on urination, salivation and defecation, respiration and blood composition.

T.A. Voronina in the article “Mexidol: main effects...” (Moscow, 2005) he writes that in animal experiments the negative aspects of Mexidol manifest themselves as follows : Mexidol inhibits motor activity and disrupts coordination of movements. Moreover, these phenomena do not appear in all experimental animals and only when using high doses of Mexidol (over three hundred mg/kg) with intraperitoneal administration of the drug and when Mexidol is administered orally in doses exceeding four hundred mg/kg.

It is important that with long-term treatment with Mexidol (from two to three months), the effect of the drug does not decrease and, at the same time, no undesirable manifestations are observed.

Besides, After long-term treatment with Mexidol, withdrawal syndrome does not appear!

Mexidol has a pronounced therapeutic effect. You can read about the drug Mexidol and its dosages for certain diseases in the article

Mexidol is a low-toxic medicine, therefore cases of overdose (if the instructions are followed) are unlikely.

Acceptable side effects of sleep disturbance (drowsiness or insomnia) pass quickly : during the day.

In some cases, with intravenous jet administration of Mexidol can appear dry mouth, metallic taste, sore throat... It is not necessary to cancel treatment with Mexidol in such cases. Gradually the negative effects weaken. It is recommended to administer the drug more slowly.
Rarely there are other side effects : nausea, allergic reactions, heartburn, increased gas formation...

When treating with Mexidol, those who suffer from bronchial asthma and suffer from hypersensitivity to sulfites should be very careful.
Patients with high/low blood pressure should be prescribed Mexidol with caution.

Mexidol has contraindications, but they are few.

This is hypersensitivity to the components of Mexidol, acute dysfunction of the kidneys and liver.
Moreover, it should be noted : the liver does not have pain receptors (sometimes the liver lining hurts, but more often the adjacent organs). This is a question that readers sometimes ask in their letters (can the liver hurt because of the medicine - because of Mexidol in particular). Mexidol has hepatoprotective properties.

The following should be noted : There have been no strictly controlled experiments with the use of Mexidol in pregnant women and during lactation, as well as in children.
Therefore, treatment with Mexidol pregnant women and women breastfeeding, contraindicated.

Treatment of children with Mexidol

Often, readers in their letters ask us the question: “How to help a child if he has eaten Mexidol tablets?”

First of all, let’s answer trivially : do everything to prevent this from happening, i.e. hide medications from children - and the further/higher the better!

Secondly, general rules for drug poisoning:

1. Give the child plenty of room temperature water to drink (do not give the child mineral water, but give any liquid without carbon dioxide).

2. Tilt the child’s upper body and press on the root of the tongue (try to induce vomiting).

3. Give the child activated carbon (a must have in any family!).

You carry out all these manipulations before the ambulance arrives, which you call immediately upon discovery of the pills eaten by the child. You should take the medicine container with you to the hospital.

Under no circumstances should you give your child milk, castor oil, or saline solution (do not give anything other than what is written above).

The description and possible side effects of Mexidol are presented below.

Description

The relatively new drug Mexidol is a nootropic. The active ingredient is hydroxymethylethylpyridine succinate. It provokes tissue respiration, which is why it is often attributed to poisoning and vascular spasms.

The mechanism of Mexidol’s work is a direct effect on brain cells, thereby protecting them from oxygen starvation and death through ischemia.

After taking Mexidol, the patient noted an improvement in well-being, rapid recovery of skills, speech and memory. Immunity against poisoning and intoxication was developed.

• Impaired cerebral circulation.
• Cardiac ischemia.
• Purulent-inflammatory infections.
• Alcohol intoxication.
• Drug poisoning.
• As a prophylaxis against aging processes.

Today there are analogues of Mexidol on the market, but they do not show such good results in treating patients. In terms of chemical composition and indications for use, only Meksifin is most equal to Mexidol.

Side effects

One of the distinctive features of the drug is that it is characterized by minimal side effects and a low level of toxicity. Research on the drug has shown how it affects the body:

• Does not depress the human psyche.
• Does not stimulate unnecessary movements.
• Does not interfere with coordination.
• Does not lower rectal temperature.
• Does not affect corneal and pineal reflexes.
• Does not provoke loss of strength and drowsiness.

The dose increased several times does not have a muscle relaxant effect on the patient. In parallel with this, no negative effect on memory or provoking the development of amnesia was observed. Some patients even experienced an improvement in brain activity after taking Maxidol.

This pharmacological drug does not have a negative effect on the liver, but rather has a hepatoprotective effect. It also does not affect the following indicators:

• Heart rate.
• Blood pressure level.
• Electrocardiogram.
• Hemodynamics and respiratory rhythm.
• Chemical components of blood.

The side effects of Mexidol are more noticeable in animals. In them, it inhibits activity and coordination when 400 mg/kg of the drug is administered intraperitoneally.

Using Mexidol for 2-3 months does not reduce its medicinal properties and does not provoke side effects. After stopping this course of treatment, patients do not experience withdrawal symptoms.

Some patients noted that after taking the medication they had minor problems with the digestive tract, namely nausea, flatulence and gastrointestinal upset. Side effects of the Mexidol tablet were manifested in the drying out of the oral cavity after taking it.

Intravenous administration of the solution in rare cases is accompanied by a mildly unpleasant metallic taste, as well as a feeling of an enveloping warm wave. Sometimes there may be a feeling of an unpleasant odor, a slight sore throat, some discomfort in the heart area and breathing problems.

In some patients, Mexidol exhibits side effects such as drowsiness. In this case, it is not recommended to drive or perform any work that requires increased concentration.

The instructions say that the medicine does not cause allergic reactions, but patients with bronchial asthma and high sensitivity to medications should take Mexidol carefully to avoid the development of severe allergies.

Overdose

Due to the low level of toxicity, the negative effect of Mexidol on the human body is minimal. Overdose is possible only with intravenous administration of the drug.

Main symptoms of overdose:

• Lack of sleep or increased sleepiness.
• Lethargy.
• Apathetic state.
• Fast fatiguability.

In some patients, sudden increases in blood pressure were observed.

If the above symptoms appear, experts recommend not to worry and continue taking the drug. As a rule, your health will improve within 24 hours.

If Mexidol has side effects in the form of regular high blood pressure, the doctor prescribes medications to lower it.

Contraindications

Mexidol is prohibited from being taken in any form by expectant mothers and nursing women, young children and people sensitive to the composition of Mexidol. These caveats are due to the fact that studies have not yet been conducted on these categories of people.

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IMPORTANT. The information on the site is provided for informational purposes only. Do not self-medicate. At the first sign of disease, consult a doctor.

Mexidol side effects

Mexidol is an original Russian-made drug.

Animal experiments have shown that Mexidol prolongs life with hypoxia of various kinds. Moreover, this effect is much better manifested in Mexidol than in drugs such as Pyritinol (Encephabol) and Piracetam.

Mexidol produces significant anti-alcohol effect, has a geroprotective (corrects processes characteristic of aging of the body) and anti-atherogenic (prevents the occurrence of pathological changes in the vessels and aorta) effect.

However, like any chemical drug, Mexidol has side effects on the body and has contraindications for its use.

In treatment, it is very important that the medication does not have a negative effect on the liver. And Mexidol has this property. Moreover, the drug has a hepatoprotective effect (protects the liver).

T.A. Voronina in the article “Mexidol: main effects...” (Moscow, 2005) he writes that in animal experiments the negative aspects of Mexidol are manifested as follows: Mexidol inhibits motor activity and upsets coordination of movements. Moreover, these phenomena do not appear in all experimental animals and only when using high doses of Mexidol (over three hundred mg/kg) with intraperitoneal administration of the drug and when Mexidol is administered orally in doses exceeding four hundred mg/kg.

It is important that with long-term treatment with Mexidol (from two to three months), the effect of the drug does not decrease and, at the same time, no undesirable manifestations are observed.

Mexidol has a pronounced therapeutic effect. You can read about the drug Mexidol and its dosages for certain diseases in the article “Mexidol - indications for use.”

Mexidol is a low-toxic medicine, therefore cases of overdose(if the instructions are followed) are unlikely.

In some cases, with intravenous jet administration of Mexidol can appear dry mouth, metallic taste, sore throat. It is not necessary to cancel treatment with Mexidol in such cases. Gradually the negative effects weaken. It is recommended to administer the drug more slowly.

Occasionally, there are other side effects: nausea, allergic reactions, heartburn, increased gas formation.

When treating with Mexidol, those who suffer from bronchial asthma and suffer from hypersensitivity to sulfites should be very careful.

Patients with high/low blood pressure should be prescribed Mexidol with caution.

Moreover, it should be noted: the liver does not have pain receptors (sometimes the liver lining hurts, but more often the adjacent organs). This is a question that readers sometimes ask in their letters (can the liver hurt because of the medicine - because of Mexidol in particular). Mexidol has hepatoprotective properties.

The following should be noted: strictly controlled experiments with the use of Mexidol in pregnant women and during lactation, as well as in children, have not been conducted.

Therefore, treatment with Mexidol pregnant women and women breastfeeding, contraindicated.

For our part, we must try to do everything in our power to distinguish a fake. Read about it here, here and here.

Often, readers in their letters ask us the question: “How to help a child if he has eaten Mexidol tablets?”

First of all, let’s answer in a trivial way: do everything to prevent this from happening, i.e. hide medications from children - and the further/higher the better!

Secondly, general rules for drug poisoning :

1. Give the child plenty of room temperature water to drink (do not give the child mineral water, but give any liquid without carbon dioxide).

2. Tilt the child’s upper body and press on the root of the tongue (try to induce vomiting).

3. Give the child activated carbon (a must have in any family!).

You carry out all these manipulations before the ambulance arrives, which you call immediately upon discovery of the pills eaten by the child. You should take the medicine container with you to the hospital.

Under no circumstances should you give your child milk, castor oil, or saline solution (do not give anything other than what is written above).

5 comments:

I took Mexidol, Mexipril, Vinpocetine, but for some reason they gave me complete insomnia, this time I bought Cavinton the same thing, and they also replaced Mexidol with meldronate, tell me, is it possible to do this?

I ask experts to answer if possible

The neurologist prescribed Mexidol tablets after an intramuscular course of 10 Mexidol injections. On the third day of taking the pills, a rash appeared on the palms, soles and head. Do I need to continue taking the drug?

Dear Azat! If a rash appears due to medications, you should stop taking them and consult your doctor immediately!

🔻🔻Important contraindications and side effects of the drug Mexidol

The drug Mexidol belongs to the group of antihypoxants and antioxidants.

In the human body it exhibits a wide range of important effects:

1. Stabilizes cell membranes.
2. Has an antioxidant effect.
3. Eliminates cellular and tissue hypoxia.
4. Aligns cell membranes.
5. Protects blood vessels in the brain.
6. It has nootropic, adaptogenic and anxiolytic effects.
7. Prevents the development of seizures.

Mexidol is produced in three dosage forms and is intended for oral administration in the form of tablets, in ampoules for intravenous and intramuscular injections and droppers.

Side effects of the drug Mexidol

Side effects from Mexidol must be taken into account and recorded during the treatment process, which can be in the form of:

1. Nausea.
2. Vomiting.
3. Alternating diarrhea with constipation.
4. Allergic reactions on the skin.
5. Dry mouth.
6. Anxiety.
7. Worries.
8. Dizziness.
9. Emotional lability.
10. Insomnia and difficulty falling asleep.
11. Headaches.
12. Discoordination of movements.
13. Unsteadiness of gait.
14. Increase or decrease in blood pressure.
15. Constant excessive moisture on the palms and feet.

The side effects of Mexidol are not always indications for discontinuing treatment. In such cases, medical monitoring of the patient’s condition, a possible temporary reduction in dosage, and a review of the frequency and time of administration are necessary. Only the doctor can decide on the patient's further actions.

Contraindications to the use of Mexidol

Mexidol is contraindicated in the following cases:

1. Children under 18 years of age, since the effectiveness and safety of the drug in children has not been proven.
2. Pregnancy.
3. Lactation.
4. Individual intolerance to the components of the drug.
5. Acute renal/liver failure.

There are very few restrictions on the use of Mexidol, so the medication is widely used in the treatment of a large number of neurological diseases.

In case of overdose

The phenomena of intoxication with Mexidol are accompanied by the development of drowsiness, which requires detoxification treatment.

Indications for use

The benefits of Mexidol are confirmed by the breadth of its indications for use. In adults, the drug is prescribed for the following pathological conditions:

1. Mild traumatic brain injuries and their consequences.
2. Encephalopathies of any origin.
3. Condition after acute cerebrovascular accident, transient ischemic attacks.
4. Subcompensated state after strokes.
5. Vegetative dystonia.
6. As an additional treatment for coronary heart disease.
7. Cognitive disorders in atherosclerotic lesions.
8. Anxiety syndrome with neurasthenia, neuroses and other neurotic reactions.
9. Asthenia.
10. Thyroid diseases.
11. Relief of alcoholic delirium and post-withdrawal syndrome.
12. Consequences of acute poisoning with antipsychotics.
13. Strong influence of stress.
14. Prevention of the development of diseases of internal organs under the influence of extreme factors.
15. Acute myocardial infarction.
16. Complex treatment of primary open-angle glaucoma.
17. Peritonitis.
18. Pancreatitis accompanied by necrosis.
19. Reducing side effects when treating oncology of the female genital organs, conducting radiation therapy, to reduce the severity of inflammation of the intestines, bladder, and urethra.

Therapeutic effect

One of the most important therapeutic effects of the drug Mexidol is increasing the resistance of the entire body to numerous factors and conditions that can cause death. The most dangerous of them are:

1. Hypoxia.
2. Ischemia.
3. Circulatory disorders.
4. Alcohol poisoning.
5. Intoxication with neuroleptics.

The action of Mexidol is based on its ability to suppress lipid peroxidation, increase the activity of superoxide dismutase and increase the lipid-protein ratio.

Thanks to the ability to change and control the activity of membrane-bound enzymes and receptor complexes, the preservation of the structure and functions of biological membranes, neurotransmitter transmission and the improvement of the quality and speed of synaptic transmission are ensured.

Stabilization of cell membranes is achieved by increasing the concentration of dopamine in the brain. This significantly increases the adaptive activation of aerobic glycolysis and increases the content of ATP in cells - one of the main sources of nutrition and energy for cells and tissues.

Treatment with Mexidol leads to an improvement in metabolic reactions and blood supply to the brain. At the same time, there is an increase in the rheological properties of blood, restoration of the consistency of the microvasculature and a decrease in the ability of platelets to stick together.

The use of Mexidol also helps to provide a hypolipidemic effect, since the drug is able to reduce the levels of total cholesterol and LDL - low-density lipoproteins.

This ability, such as stabilizing the cellular elements of red blood cells and platelets, exhibits an excellent therapeutic effect in hemolysis, preventing the pathological process from developing.

The effect on the nervous system is enormous. Thanks to its mechanisms of action, Mexidol is capable of:

1. Exhibit an anti-stress effect.
2. Restore the body during the period after stress and correct behavior.
3. Regulate your sleep cycle and phases.
4. Correct somatovegetative reactions.
5. Improve memory and the ability to remember and reproduce received information.
6. Suppress the development of dystrophy and structural changes in various parts of the brain.

The therapeutic effects of Mexidol on the cardiovascular system also deserve special attention:

1. Improves the function of areas of the heart muscle that have been subjected to ischemia.
2. In case of insufficiency of coronary vessels, it increases collateral circulation of ischemic areas.
3. Increases the endurance of cardiomyocytes, prevents the loss of their integrity and supports the functions of heart cells.
4. In case of reversible processes that led to dysfunction of the heart, it restores myocardial contractility.

In general, Mexidol occupies a worthy place among medications, as evidenced by reviews from doctors and patients. The range of its therapeutic effects allows one to achieve excellent results in the treatment of neurological diseases and heart pathologies. Moreover, the price of Mexidol allows each patient who is prescribed such a drug to undergo the necessary courses of treatment.

Mexidol: side effects, reviews, description, consequences of taking

The drug Mexidol belongs to the group of antihypoxants. The medicine is used for various disorders accompanied by a lack of oxygen in the brain tissue. Like any other drug, Mexidol can cause the development of severe side symptoms. To find out the degree of risk when taking it, you need to find out the main side effects and reviews of Mexidol.

When is Mexidol prescribed?

The medicine reduces the sensitivity of brain tissue to various types of pathogenic factors. These include hypoxia, ischemic phenomena, states of shock, acute chemical intoxication, including narcotic drugs, alcohol, and antipsychotic drugs.

The medication is used to treat a wide range of diseases. The medicine is available in the form of tablets intended for internal use. The drug is also prescribed in the form of a liquid solution, which is introduced into the body by drops. To treat diseases of the oral cavity, Mexidol Dent toothpaste is produced.

The main indications for use are:

• Withdrawal syndrome accompanied by neuroses
• Vegetative-vascular dystonia
• Disorders of blood circulation in brain tissue due to trauma
• Ischemic and hemorrhagic strokes
• Cognitive impairment due to cerebral atherosclerosis
• Encephalopathy
• Anxiety disorders
• Poisoning caused by long-term use of antipsychotic drugs

In addition to pronounced pathological processes, the medicine is prescribed for preventive purposes. The drug is used to prevent asthenic manifestations that occur when the patient is in unfavorable conditions, exposed to extreme factors or increased physical activity.

In general, indications for taking Mexidol cover a wide range of pathologies, but the medicine is also prescribed for preventive purposes.

Features of application

The method of introducing the drug into the body and the dosage are prescribed individually. The main criterion when forming a therapeutic course is the nature of the pathology. The individual characteristics of the patient are also taken into account.

• Traumatic brain injuries. Mexidol tablets are used. The maximum daily dose is 800 mg. The presented amount of the drug should be divided into 3-4 doses. The duration of therapy is from 5 days to 2 months.

Thus, Mexidol must be taken in strict accordance with the prescribed dosages, since otherwise the likelihood of side effects increases.

Side effects when taking

Mexidol is characterized by rapid absorption and low toxicity, and therefore in the vast majority of cases it is tolerated by the body without causing negative consequences. Therapy is rarely accompanied by side effects, and they usually do not require special treatment.

Possible side effects include:

• Dry mouth
• Dizziness
• Nausea
• Skin rashes
• Itching and burning

An overdose of the drug is possible only if the dose has been increased several times. It is believed that the drug does not cause side effects when combined with other drugs. An increased effect is noted when taking Mexidol and drugs belonging to the groups of anticonvulsants, antidepressants, and anxiolytics simultaneously. Also, the described medicine reduces the toxic effects of ethyl alcohol on the body.

The development of side effects during the use of Mexidol occurs in rare cases, and the nature of the symptoms that arise is individual.

Reviews

The drug is characterized by predominantly positive reviews. Moreover, not only patients, but also doctors from various fields respond well to the medicine.

• The doctor prescribed Mexidol drips for the mother – she has Parkinson’s disease. The drug is very effective. My mother’s tremors went away, her sleep and memory improved, and her fine motor skills were restored.
• I took Mexidol in combination with Mildronate as prescribed by a doctor. Before the appointment I had a constant headache. A pronounced effect appeared within 2 days from the start of administration. The headaches have become less intense, the depression has passed, and my mood has improved.
• Mexidol was taken in combination with Cerebrolysin for the treatment of VSD. After the first course of treatment, symptoms began to appear less frequently. I am especially pleased with the absence of panic attacks and pronounced feelings of anxiety.
• The drug was prescribed after injury received during a traffic accident. Mexidol prescribed by the doctor turned out to be ineffective. As a result, the doctor replaced this medicine with Amelotex.
• After taking 1 tablet of Mexidol, I felt severe dizziness. After this, a feeling of constriction in the chest and vomiting appeared. I had to rinse my stomach and go on a diet for a while. The doctor said that the reason for the side effects is that the stomach is irritated.

Thus, the drug Mexidol has many positive reviews, but there are also those patients who speak negatively about the drug due to the side effects that have arisen.

Mexidol is a popular drug that is used for various pathologies accompanied by impaired blood circulation in the brain. Taking it rarely provokes side effects, but the development of nausea, dizziness, and allergic reactions is possible.

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Address: Moscow, Verkhnyaya Syromyatnicheskaya street, 2, office. 48

Mexidol instructions for use, contraindications, side effects, reviews

Active substance of the drug: non appropriated

ATX encoding: V03AX

KFG: Antioxidant drug

Registration number: P No. 002161/01

Registration date: 03/14/08

Owner reg. credential: PHARMASOFT NPK LLC

Mexidol release form, drug packaging and composition.

2 ml - glass ampoules (5) - contour cell packaging (1) - cardboard packs.

2 ml - glass ampoules (5) - contour cell packaging (2) - cardboard packs.

The solution for intravenous and intramuscular administration is colorless or slightly yellowish, transparent.

Solution for intravenous and intramuscular administration

Excipients: water for injection.

5 ml - glass ampoules (5) - contour cell packaging (1) - cardboard packs.

5 ml - glass ampoules (5) - contour cell packaging (2) - cardboard packs.

The description of the drug is based on the officially approved instructions for use.

Pharmacological action of Mexidol

Antioxidant drug. It has antihypoxic, membrane protective, nootropic, anticonvulsant and anxiolytic effects. The drug increases the body's resistance to the effects of various damaging factors, to oxygen-dependent pathological conditions (shock, hypoxia and ischemia, cerebrovascular accidents, intoxication with alcohol and antipsychotics /neuroleptics/).

Mexidol improves metabolism and blood supply to the brain, improves microcirculation and rheological properties of blood, and reduces platelet aggregation. Stabilizes the membrane structures of blood cells (erythrocytes and platelets) during hemolysis. It has a lipid-lowering effect, reduces the content of total cholesterol and low-density lipoproteins.

The mechanism of action of Mexidol is due to its antioxidant, antihypoxic and membrane protective effects. The drug inhibits lipid peroxidation, increases the activity of superoxide dismutase, increases the lipid-protein ratio, reduces membrane viscosity, and increases its fluidity. Mexidol modulates the activity of membrane-bound enzymes (calcium-independent phosphodiesterase, adenylate cyclase, acetylcholinesterase), receptor complexes (benzodiazepine, GABA, acetylcholine), which enhances their ability to bind to ligands, helps preserve the structural and functional organization of biomembranes, neurotransmitter transport and improve synaptic transmission. Mexidol increases dopamine levels in the brain. Causes an increase in compensatory activation of aerobic glycolysis and a decrease in the degree of inhibition of oxidative processes in the Krebs cycle under hypoxic conditions with an increase in the content of ATP and creatine phosphate, activation of the energy-synthesizing functions of mitochondria, stabilization of cell membranes.

Reduces enzymatic toxemia and endogenous intoxication in acute pancreatitis.

Pharmacokinetics of the drug.

When Mexidol is administered in doses of mg, Cmax in plasma is 3.5-4.0 mcg/ml and is achieved within 0.45-0.5 hours.

Quickly distributed in organs and tissues.

After intramuscular administration, the drug is determined in the blood plasma within 4 hours. The average retention time of the drug in the body is 0.7-1.3 hours.

It is quickly excreted from the body in the urine, mainly in glucuron-conjugated form and in small quantities unchanged.

Indications for use:

Acute cerebrovascular accidents;

Mild cognitive disorders of atherosclerotic origin;

Anxiety disorders in neurotic and neurosis-like conditions;

Relief of withdrawal syndrome in alcoholism with a predominance of neurosis-like and vegetative-vascular disorders;

Acute intoxication with antipsychotic drugs;

Acute purulent-inflammatory processes of the abdominal cavity (acute pancreatitis, peritonitis) as part of complex therapy.

Dosage and method of administration of the drug.

Mexidol is administered intramuscularly or intravenously (stream or drip). To prepare a solution for infusion, the drug should be diluted with isotonic sodium chloride solution.

Mexidol is administered in a stream slowly, over 5-7 minutes, dropwise at a rate of drops/min. The maximum daily dose is 1200 mg.

In case of acute cerebrovascular accidents, Mexidol is used in complex therapy in the first day by intravenous drip 2-4 times a day, then by intramuscular injection 3 times a day for 2 weeks.

For discirculatory encephalopathy in the decompensation phase, Mexidol is used intravenously in a stream or drip 1-2 times a day for 14 days, then intramuscularly per day for the next 2 weeks.

To carry out a course of prophylaxis of discirculatory encephalopathy, Mexidol is prescribed intramuscularly 2 times a day during the day.

For mild cognitive impairment in elderly patients and for anxiety disorders, Mexidol is prescribed intramuscularly once a day for a day.

For alcohol withdrawal syndrome, Mexidol is administered intravenously or intramuscularly 2-3 times a day for 5-7 days.

In case of acute intoxication with antipsychotic drugs, Mexidol is administered intravenously at doses per day for 7-14 days.

In acute purulent-inflammatory processes of the abdominal cavity (acute necrotizing pancreatitis, peritonitis), Mexidol is prescribed on the first day both in the preoperative and postoperative periods. The dose of the drug depends on the form and severity of the disease, the prevalence of the process, and variants of the clinical course. Discontinuation of the drug should be done gradually, only after a stable positive clinical and laboratory effect.

For acute edematous (interstitial) pancreatitis, Mexidol is prescribed pomg 3 times a day intravenously (in isotonic sodium chloride solution) and intramuscularly.

For necrotizing pancreatitis of mild severity, Mexidol is prescribed pomg 3 times a day intravenously (in isotonic sodium chloride solution) and intramuscularly.

For necrotizing pancreatitis of moderate severity - 200 mg 3 times a day intravenously (in isotonic sodium chloride solution).

For severe necrotizing pancreatitis - at a dose of 800 mg on the first day, with a double dose regimen, then - 2 times a day with a gradual reduction in the daily dose.

In extremely severe forms of necrotizing pancreatitis, the initial dose is 800 mg/day until the manifestations of pancreatogenic shock are persistently relieved; when the condition is stabilized, 2 times/day intravenously (in isotonic sodium chloride solution) with a gradual reduction in the daily dose.

Course therapy of the drug is completed gradually only after a stable clinical and laboratory effect.

Side effects of Mexidol:

From the digestive system: nausea, dry mouth.

Other: allergic reactions, drowsiness.

Contraindications to the drug:

Acute liver dysfunction;

Acute renal dysfunction;

Lactation period (breastfeeding);

Hypersensitivity to the drug.

Use during pregnancy and lactation.

Mexidol is contraindicated during pregnancy and lactation (breastfeeding) due to insufficient knowledge of the drug's effect.

Special instructions for the use of Mexidol.

The degree of restrictions on use is determined by individual tolerability of the drug.

Drug overdose:

In case of overdose, drowsiness may develop.

Interaction of Mexidol with other drugs.

When used together, Mexidol enhances the effect of benzodiazepine derivative anxiolytics, antiparkinsonian (levodopa) and anticonvulsant (carbamazepine) drugs.

Mexidol reduces the toxic effect of ethyl alcohol.

Terms of sale in pharmacies.

The drug is available with a prescription.

Terms of storage conditions for the drug Mexidol.

List B. The drug should be stored out of the reach of children, in a dry place, protected from light at a temperature not exceeding 25°C. Shelf life - 3 years.

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Maalox instructions for use, contraindications, side effects, reviews

Maalox - updated description of the drug, you can see the pharmacological action, side effects, dosage of the drug Maalox. .

The material is published for informational purposes only and under no circumstances can it be considered a substitute for medical consultation with a specialist in a medical institution. The site administration is not responsible for the results of using the posted information. For questions of diagnosis and treatment, as well as prescribing medications and determining their dosage regimen, we recommend that you consult a doctor.

The circulatory system serves as the body's highways, providing its parts with nutrition and oxygen.

Ensuring a sufficient level of blood supply is critical for the normal functioning of internal organs, especially the brain.

It is known that in case of problems with blood circulation, brain dysfunction can occur, and even a very short period of oxygen starvation negatively affects this important organ. A modern remedy, Mexidol, helps solve this problem effectively and safely.

Circulatory disorders can occur due to a variety of diseases. The most common causes of such dysfunction are cardiovascular diseases - stroke, encephalopathy, atherosclerosis.

Today, effective drugs have been developed that help prevent insufficient oxygen supply to the brain. But does Mexidol increase or decrease blood pressure? How does the drug affect the body in general?

Mexidol is designed for use in neurology, surgery and even psychiatry. It is used for:

• circulatory disorders, including cerebral ones;
• vegetative-vascular dystonia;
• disorders of brain function in atherosclerosis;
• withdrawal syndrome caused by alcoholism.

Mexidol is used as part of complex therapy. In addition, this remedy is applicable in the treatment of peritonitis, acute forms of pancreatitis, as well as relieving the consequences of an overdose of antipsychotics.

In all these cases, Mexidol showed a fairly high effectiveness of use. The use of the drug for the treatment and prevention of asthenic conditions, cardiac ischemia, and cognitive disorders is also allowed and recommended. The use of Mexidol is also indicated for persistent exposure to stress-forming factors and excessive psychological or physical stress.

This list is not complete - the drug is recommended for use for the treatment of a fairly wide range of diseases and dysfunctions associated with insufficient blood supply to internal organs.

Mexidol injection solution

The industry produces this drug in two main forms - for oral use and for injection. Film-coated tablets weighing 125 mg are administered orally. For injections, capsules of a five percent solution of the active substance with a volume of two milliliters are produced. Pharmacology does not produce other dosage forms of this drug.

Is it possible to drink Mexidol with high blood pressure? It is possible and sometimes necessary, but only as prescribed by a doctor. The fact is that there is no clear answer to the question of whether Mexidol increases or decreases. This mainly depends on the individual characteristics of the patient. Therefore, Mexidol with high blood pressure can bring both benefit and harm. T

Biochemistry of the drug's effects

The biochemical effect of Mexidol differs from the action of drugs of the neuropsychotropic group. Unlike the latter, which act on certain receptors, it inhibits free radical oxidation in the body.

Under the influence of the active substances of the drug, certain antioxidant enzymes are activated. Mexidol has a beneficial effect on the cell membrane, restoring its functionality, reduces the colloidality of the lipid layer, and increases the activity of mitochondria.

As a result, energy metabolism at the cellular level improves, which leads to restoration of the apparatus and structure of cell membranes. These positive changes, in turn, through complex biochemical processes affect the stabilization of neural connections, significantly increasing the effectiveness of neurotransmitters - special substances that serve to transmit impulses coming from the body's nerve cells.

At the same time, antioxidant processes are enhanced, which has a beneficial effect on the functionality of cells and the organ as a whole. In addition, Mexidol reduces blood pressure and can bind free lipids. This effect of the drug leads to a significant anti-cholesterol effect from its use, which improves the quality of blood vessels.

This allows Mexidol to effectively influence the mechanism of occurrence and development of a wide range of diseases, suppressing them, and initiate the launch of protective biochemical reactions of the body itself.

Moreover, the drug is non-toxic, and its targeted effect causes fewer side effects and unwanted reactions of the body than the effect of antipsychotics.

Mexidol is also used as a prophylactic agent.

Medicinal effects

The pharmacological effects of taking Mexidol are very diverse. It acts both on a deeper level, improving neural connections, and on a more general level, significantly improving the patency of the circulatory system. As a result, the effect of its use is very broad and pronounced in various pathologies.

Mexidol blood pressure tablets

Mexidol protects the central nervous system, having vegetotropic and antiparksonian effects. Relieves neurotic deficiency, has anti-alcohol and tranquilizing effects. Can Mexidol lower blood pressure?

Yes, taking the drug can improve cerebral circulation, increase the lifespan of platelets, while simultaneously reducing the level of blood density and reducing the risk of developing blood clots.

The overall level of bad cholesterol also decreases. The action of Mexidol has a beneficial effect on the body's resistance to various external aggressive factors. Resistance to shock, situations, prolonged lack of sleep or disruption of its cycles and patterns increases.

The body's resistance to ethanol and some other substances that cause intoxication, including medications, increases.

In addition, the product has a pronounced anti-stress effect. Its intake leads to normalization of post-stress processes and reactions, normalization of sleep.

Reduces the impact on the cardiovascular system, reducing the risk of developing pathologies of the brain and myocardium, the occurrence of which is associated with psychological stress. The anticonvulsant effect of Mexidol occurs regardless of the pathogenesis of seizures.

The drug is effective for relieving chronic processes associated with excitation of epileptiform brain activity. At the same time, the remedy also helps with convulsions caused by external factors, such as the administration of certain medications.

Taking Mexidol improves memory functions, increases learning ability, and reduces the intensity of processes that lead to forgetting previously acquired knowledge, skills and abilities.

Impairments in memory and functions of the higher nervous system, caused by various traumatic effects - electric shock, severe blows to the head, compression injuries of the brain, as well as the action of drugs scopolamine, benzodeazipine and others, are also relieved.

The effect of post-alcohol amnesia and deterioration in the narrative functions of the human brain are also reduced.

Laboratory studies have revealed the ability of Mexidol to have a beneficial effect on internal organs experiencing insufficient blood supply. Mexidol is an active anti-dihypoxant, its action is based on the activation of energy-synthesizing functions of cells.

A number of experiments conducted - both on experimental animals and on isolated organs that had undergone perforation - showed the effect of the drug during hypobaric oxygen starvation, including those accompanied by an excess of carbon dioxide accumulated in the tissues of the organ.

In terms of this effect, Mexidol is significantly superior to such well-known drugs as piracetam and pyritinol.

These drugs can relatively effectively combat the lack of oxygen only with a very large dosage, and the oversaturation of cells with carbon dioxide reduces the effectiveness of their effects to almost zero.

In addition, side effects from overdoses of these drugs often do not allow them to be used effectively. In addition, the drug has a positive effect on human catabolism due to the presence of succinic acid salts in its composition. These substances act as catalysts for the tricarboxylic acid cycle, the most important chemical process at the cellular level.

A clearly calculated amount of this substance, which is a toxic agent in case of overdose, is not capable of causing harm to health, but can actively improve cellular respiration. Thus, this succinate enhances the beneficial effects of Mexidol.

A specialist can prescribe the drug for dysfunctions not related to the brain. Mexidol is sometimes used for low blood pressure and, oddly enough, for high blood pressure too.

Side effects

Studies have revealed a low level of side effects of Mexidol and a virtual absence of negative effects on the body if used correctly. The main side effect of the drug begins to appear if the maximum permissible dosage is radically exceeded.

An overdose of the drug threatens the occurrence of disorders of the body's motor functions and general inhibition of motor skills. Coordination of movements may be impaired, and reflex muscle contraction may decrease.

Mexidol slightly increases blood pressure, causes drowsiness, and depression. Such side effects were recorded only in 2–3 percent of patients taking the drug, mainly among those undergoing treatment for alcohol dependence.

At the same time, even hyperdoses of Mexidol do not cause side effects characteristic of many other drugs. For example, there was no negative effect of the drug on liver function. On the contrary, if the dose is exceeded, the medicine begins to act on the body as a hepatoprotector, restoring the functionality of this organ.

There was no memory deterioration, drowsiness or disturbances in brain function. The drug is not addictive.

The product does not affect body temperature, heart and kidney function.

There were no problems with respiratory function, vision, or other side effects even during long-term use, over two to three months.

Any combination of Mexidol and other medications should be taken after consultation with a specialist.

Interaction and methods of drug administration

Mexidol interacts with most somatic drugs without causing any unwanted effects or inhibiting their action.

The use of this drug enhances the therapeutic effect of taking antidepressants, anticonvulsants, and drugs used to treat the brain in Parkinson's disease.

At the same time, Mexidol can reduce the toxic effects of the components of certain drugs on the body. The drug is taken orally, in the form of tablets, 2-3 times a day. The maximum dose is 6 tablets per day.

Treatment lasts from 6 days to 6 weeks, treatment is discontinued by gradually reducing the dosage used. The instructions for use accompanying the drug Mexidol do not indicate at what pressure its use is indicated.

The injective form of Mexidol is administered via a syringe or by drip.

In the first case, both intravenous and intramuscular administration are allowed, and these methods can be used in one course of treatment, combined with each other.

Jet and drip administration involves the use of sixteen milliliters of sodium chloride per 200 milligrams of the active substance.

It is undesirable to abruptly stop taking the drug. An indication for it can only be individual intolerance.

Video on the topic

Does the drug Mexidol lower blood pressure or not? What effect can be expected from taking it? Answers in the video:

In general, Mexidol is a modern drug characterized by a number of positive properties. First of all, it is worth noting its high medicinal effectiveness and wide application profile. In addition, this drug has no side effects and does not cause health problems even with long-term use.

Another undoubted advantage is the high variability of the effective combination of Mexidol with other somatic drugs. The active substances used do not cause addiction or allergic reactions, and the variety of forms of the drug and methods of its administration allow for effective treatment of various groups of patients.

To optimize the functioning of the body, it is appropriate to take an additional course of prescribed medications. You should choose Mexidol if you need to influence the body’s resources, support the functions and tone of internal systems, especially the central nervous system. Unauthorized use of the drug is strictly contraindicated.

Mexidol - indications for use

This synthetic antioxidant is suitable for internal use. It is produced as a liquid solution for injection and in the form of pills. If the doctor has prescribed Mexidol, the indications for use should be discussed in advance, cases of overdose and contraindications should be excluded. In case of drug incompatibility, it is worth choosing a more gentle analogue with a mild effect on the site of pathology.

The active substance of the chemical formula is ethylmethylhydroxypyridine succinate. The synthetic component improves tissue respiration, which is especially important for all types of hypoxia. In addition, it provides high-quality nutrition to tissues and effectively fights the products of intoxication in the body. The therapeutic effect is almost instantaneous, especially if these are intramuscular injections for shock conditions.

In tablets

This is the most affordable form of release for a sick person: it is possible to buy tablets without a prescription at any pharmacy. The use of Mexidol should be based on the recommendations of a specialist and study of the instructions. If you use the medicine correctly, you can protect the body from intoxication and prevent the appearance of foci of necrosis against the background of spontaneously progressive oxygen starvation. Mexidol (tablets) is prescribed for such conditions of the body as:

• systemic circulatory disorder;
• previous strokes;
• general intoxication of the body;
• encephalopathy;
• long-term stressful conditions;
• extensive nerve damage;
• infectious and inflammatory processes in the body.

Mexidol's instructions tell you how to properly use this medicine in practice. The initial dose of the drug is defined as 1-2 tablets twice a day, but then, on the recommendation of a doctor, it can be increased to 1-2 tablets three times a day. The maximum portion of ethylmethylhydroxypyridine per day is 800 mg, i.e. 6 tablets. Exceeding the daily norms, according to the instructions for use, can lead to an overdose. The duration of therapy varies from 2 to 6 weeks, and must be discussed with the attending physician.

In ampoules

The second form of release of this medicine is a solution for injection. If regular Mexidol is prescribed in this form, ampoules are also available without a prescription. The release version is more effective, since the component - methylhydroxypyridine - immediately enters the systemic bloodstream, has a therapeutic effect, and gives a stable and long-lasting therapeutic effect. The medicine has antioxidant, nootropic, antihypoxic and anxiolytic properties. Indications for use are:

• insufficient nutrition of brain tissue;
• impaired systemic circulation of the cerebral cortex and not only;
• nervous disorders with panic attacks, anxiety states;
• impaired cognitive function;
• open angle glaucoma.

The medication Mexidol in ampoules according to the instructions is administered into the patient’s body intramuscularly or intravenously. It is important to discuss single doses and course duration with your doctor in advance. A similar summary of Mexidol states that a single dose of medication depends on the nature of the pathological process and the degree of neglect of the diagnosed disease. These may be the following standards:

1. Impaired cerebral circulation - 200-500 mg of medication / 14 days.
2. Traumatic brain injuries – 500 mg / 14 days.
3. Circulatory insufficiency in the cerebral cortex – 100-250 ml / 10 days.

Side effects

Before prescribing a medicine, the doctor studies its description, excludes contraindications, side effects, and incompatibility with other pharmacological groups as part of complex treatment. This will help prevent a deterioration in the patient’s general well-being and speed up recovery. After prescribing the drug, keep in mind that Mexidol has the following side effects:

• signs of dyspepsia of varying severity;
• local allergic reactions.

Mexidol for children

Tablets and injections are prescribed to small patients for traumatic brain injuries and purulent neuroinfections. The dosage is indicated in the instructions for use, but clearly requires systematic medical supervision and correction strictly according to medical indications. Mexidol is not harmful for children, but there are age restrictions that it is better not to violate.

Mexidol during pregnancy

The drug does not help expectant mothers recover quickly, but can only harm the intrauterine development of the fetus and provoke extensive pathologies. Clinical studies of such categories of patients have been carried out, therefore the drug Mexidol is not prescribed during pregnancy. In addition, the medication is contraindicated during lactation.

Contraindications

Considering the fact of drug interactions, it becomes obvious that not all patients can use this medication. If you are interested in Mexidol, the first step is to study the contraindications. The manufacturer reports that taking tablets and injections is not recommended if the clinical picture includes:

• renal failure;
• liver problems;
• hypersensitivity to synthetic components.

Mexidol - analogues

If these injections give an allergic reaction, adjustment of the treatment regimen is necessary. Mexidol analogues also act productively, the main thing is to choose the safest medication for a specific clinical picture. According to doctors, Cerecard, Mexiprim, Mexidant, Neurox, Mexicor have proven themselves well.

Price

The cost of the drug is affordable to almost all patients, and varies between 250-400 rubles per pack of tablets. The price of injections remains approximately within the same price range. It is important to read the instructions before purchasing. The price on the Internet is cheaper, real reviews of high efficiency are positive. If you buy medicine at a pharmacy, the price depends on the city and region. No prescription required.

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