Genferon drops instructions for use. Proper use of Genferon Light suppositories for children of all ages. Dosage and administration

Mode of application

Side effects

Contraindications

Pregnancy

Interaction with other drugs

Overdose

Storage conditions

Release form

Compound

Additionally

Main settings

Some facts about the product:

Instructions for use

Price in online pharmacy website: from 285

Description of the medicine

Genferon Light refers to combined pharmaceutical agents with immunomodulatory, antiviral and antioxidant effects. The chemical components of the drug initiate biochemical reactions of a local-zonal and systemic nature, blocking the development of pathological disorders. Genferon light, the use of which has virtually no contraindications, promotes tissue regeneration in damaged areas, stabilizes metabolic processes, and also has a membrane-stabilizing effect at the cellular level. When Genferon Light suppositories are indicated for children, the dosage and frequency of administration must be strictly observed.

Genferon Light contains two active components:

• interferon, which is a recombinant genetically modified analogue of interferon produced by the human body;
• taurine is a powerful antioxidant that stimulates the bioactivity of the main component.

• interferon - single dose 125,000 IU/250,000 IU;
• taurine - 0.005 g.

• macrogol 1500;
• liquid for solutions;
• dextran 60000;
• citric acid solution;
• polysorbate 80.

• interferon - 5000 IU;
• taurine - 0.001g.

• disodium (edetate dihydrate) - 0.021 mg;
• sodium hydrogen phosphate - 0.114 mg;
• polysorbate 80 - 1.2 mg;
• glycerol - 7.1 mg;
• NaCl - 0.80 mg;
• peppermint (oil) - 0.02 mg;
• KCl - 0.01 mg;
• potassium dihydrogen phosphate - 0.01 mg;
• dextran 40000 - 2.35 mg;
• liquid for solutions;
• methyl parahydroxybenzoate - 0.03 mg.

Indications

Suppositories and sprays Genferon Light, the use of which has no age restrictions, are often used as one of the elements of complex therapeutic treatment:

• infectious diseases of viral-bacterial etiology;
• inflammatory urogenital processes in children developing during a course of treatment prescribed and supervised by a specialist;
• ARVI and influenza infections.

Contraindications

The use of suppositories is contraindicated if the patient is intolerant of the main components of the drug. The use of Genferon Light spray is contraindicated in case of hypersensitivity to the components of the solution, as well as in children under fourteen years of age. The prescription of suppositories should be carried out with great caution if the patient develops signs of autoimmune exacerbations and allergic relapses.

Dosage

When using the suppository form of the drug:

• for adults and children who have crossed the seven-year mark, the recommended dose of interferon is 250,000 IU/supp;
• the same doses are also indicated for pregnant women with a period of 13-40 weeks;
• The administration of Genferon Light to children under seven years of age and infants should be limited to a dose of 125,000 IU/supp.

Side effects

Genferon Light is unique in that there are no side effects when taking it in the vast majority of patients. Statistics show that only in one case out of 10,000 mild allergic reactions were observed, the symptoms of which completely disappeared 72 hours after using the medicine. If you happen to be one of them, consult your doctor. When testing the drug for compatibility with alcohol, no unexpected reactions were recorded.

Overdose

To date, no clinical consequences from exceeding the dosage of Genferon Light have been recorded. If you accidentally administer more than one suppository at a time, or increase the frequency of use of the spray, you should stop taking the drug for a day and then return to your usual dosage regimen. Genferon Light nasal sprays are available in pharmacies without a prescription, since there are currently no serious contraindications to their use.

Use during pregnancy

Clinical studies have proven the effectiveness and absence of adverse reactions in women who used Genferon Light medications during pregnancy. From the 13th week until the end of the term, the use of Genferon Light suppositories and sprays is absolutely safe. An exception exists only for the 1st trimester. There are also no restrictions for women while breastfeeding.

Application for children

The use of the drug by children under 7 years of age is allowed only in cases of extreme necessity and strictly as prescribed by a doctor. For other children there are practically no restrictions.

special instructions

No effect of the drug on the speed of reaction and the general well-being of patients was noted, therefore, for people whose professional responsibilities include driving, there are no contraindications after taking the medicine.

Drug interactions

Parallel administration of vaginal-rectal forms of Genferon Light and drugs with antibacterial, antiviral and fungicidal action has proven its clinical effectiveness. The therapeutic effect of combining the time of taking these drugs occurs due to the mutual potentiation of the activity of their components.

Storage conditions and periods

Genferon Light sprays and suppositories must be stored in a cool place. Storage temperature range is from 2 to 8 degrees. The storage location should be inaccessible to children. Safe use of the drug is guaranteed by the manufacturer for two years. You can purchase Genferon Light in Moscow without any problems. Just don’t forget that candles with this name are available with a prescription.

Compound suppositories for rectal or nasal use:

1 candle (suppository) includes: recombinant human alpha-2b – 250,000 IU or 125,000 IU (depending on dosage), taurine – 5.0 mg.

Excipients: macrogol 1500, polysorbate 80, citric acid, T2 emulsifier, hard fat 60000, sodium hydrogen citrate, purified water - the amount required to obtain a candle weighing 0.8 g.

Compound spray for nasal use:

One dose of the drug contains: recombinant human alpha-2b – 50,000 IU, – 1.0 mg.

Excipients: dextran 40000, disodium edetate dihydrate, sodium chloride, potassium dihydrogen phosphate, potassium chloride, polysorbate 80, methyl parahydroxybenzoate, sodium hydrogen phosphate dodecahydrate, peppermint oil, water for injection in the required quantity.

Release form

For candles:

Candles are white or straw colored. They have a cylindrical shape, a pointed end, and are uniform in the longitudinal section, but the presence of air inclusions is allowed. Produced in cardboard packs, inside one such pack there are 1 or 2 contour packages containing 5 suppositories each.

For nasal spray:

Light transparent liquid in tinted glass bottles, equipped with a dispenser with a safety cap in the upper part; There is one such bottle in a cardboard box. 1 bottle contains 100 doses.

pharmachologic effect

The pharmacological effect of the drug Genferon Light is due to the presence of interferon alfa-2b and taurine in the composition. They have the following properties:

• immunomodulatory effect (harmonization of immune functions);
• antiviral effect;
• antiproliferative effect (inhibition of the proliferation of bacteria and cancer cells);
• immunostimulating effect (improving the effectiveness of the immune system);
• indirect antimicrobial effect;
• anti-inflammatory effect.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The main active ingredient of Genferon Light is alpha-2b . It is obtained by modifying bacteria Escherichia coli using genetic engineering.

Interferon is capable of indirectly influencing intracellular pathogens (and viruses ), changing cell metabolism and stopping their intracellular replication and further spread. Interferon also affects neighboring cells, initiating reactions that lead to inhibition of the production of viral proteins. The result of the effect of interferon on neighboring cells is an increase in the synthesis of substances that reduce protein synthesis. This mechanism is detrimental to the virus, because blocks its further reproduction. In addition, interferon activates a number of genes that play an important role in the cell’s antiviral defense and triggers the death mechanism of the infected cell.

Another direction of interferon action is activation. The result of this activation is a more effective fight between immune system cells (killer T cells, phagocytes and helper T cells) against viruses and bacteria.

Taurine improves the metabolism of individual cells and tissues as a whole, stimulates reparative (restorative) processes. It improves and stabilizes the structure of cell membranes. Taurine is an antioxidant - by interacting with reactive oxygen compounds in the body, it prevents tissue damage from these compounds.

Pharmacokinetics

For rectal use of the drug it is typical bioavailability reaching 80% or more, which is associated with pronounced local and complex immunomodulatory effect . Vaginal use is characterized by a pronounced local effect (a high concentration of the drug is achieved in the pathological focus) and an insignificant systemic effect (the drug practically does not penetrate into the bloodstream through the mucous membranes of the internal genital organs). As a result, a pronounced local antiviral, antiproliferative and antibacterial effects.

Interferon reaches its maximum concentration in the blood 4-6 hours after administration. It is excreted mainly by the kidneys. The half-life is about 12 hours, resulting in the need for twice the drug during the day.

Intranasal use is characterized by pronounced immunostimulating and antiviral effect (due to high concentration in the pathological focus). The entry of the drug into the bloodstream with this route of administration does not reach large values ​​due to the special molecular structure of the membranes of the cells of the nasopharyngeal mucosa. However, a certain amount of interferon still enters the blood, causing a complex immunomodulatory effect .

Indications for use

Genferon Light in the form of suppositories is part of complex therapy and is used in the prevention of the following diseases in adults and children:

• gardnerellosis;
• vaginal;
• vulvovaginitis;
• balanoposthitis;
• ARVI;
• flu.

Genferon Light in the form of a nasal spray is used for prevention and therapy .

Contraindications

Contraindications when using Genferon Light suppositories:

• first 12 weeks of pregnancy;
• epilepsy or other convulsive conditions;
• severe cardiac conditions;

In patients suffering from autoimmune diseases ( Hashimoto , etc.) or in the past, Genferon Light suppositories were used under close control and supervision.

Contraindications when using Genferon Light nasal spray:

• individual sensitivity to interferon or other substances in the drug;
• age up to 14 years.

The drug should be used with caution in patients prone to nosebleeds.

Side effects

Typically, Genferon Light in the form of suppositories is well tolerated by patients. Local (at the site of drug administration) itching or burning may occur. These symptoms disappear within three days after stopping the drug. To continue treatment, it is better to consult with your doctor.

Systemic reactions may be observed, such as increased fatigue, loss of appetite, muscle, joint and headaches, as well as a decrease in the amount in the blood. But these reactions occur more often when the total administered dose of 10,000,000 IU per day is exceeded.

No side effects were observed when using Genferon Light spray.

Instructions for use

To eliminate the possibility of an overdose or side effects from Genferon Light suppositories, the instructions prescribe that children under 7 years of age should use only 125,000 IU suppositories. For children over 7 years of age, a dosage of 250 thousand IU is recommended. It is also worth noting that it is unacceptable to simultaneously use nasal drops (for treating the nasal cavity) and Genferon Light nasal spray; the instructions for use warn of the possible ineffectiveness of the drugs if the rules for their separate administration are not followed. For the treatment of pregnant women with a period of 13–40 weeks, the use of suppositories with a dosage of 250,000 IU is recommended.

• , and other acute viral diseases in children: 1 suppository rectally every 12 hours as an addition to the main treatment for 5 days. If symptoms do not disappear, it is possible to extend treatment after a five-day break.
• Chronic viral diseases in children: 1 suppository rectally twice a day as an addition to the main treatment for 10 days. Then for 5-15 weeks - 1 candle every other day in the evening.
• Acute diseases of the genitourinary system infectious in children: 1 suppository rectally twice a day for 10 days.
• Infectious diseases of the genitourinary system in pregnant women: 1 suppository rectally twice a day for 10 days.
• Infectious diseases of the genitourinary system in women: 1 suppository of 250,000 IU twice a day for 10 days (vaginally or rectally). In case of protracted course of the disease, it is possible to use 1 suppository every other day in the evening for 5-15 weeks.

Genferon Light spray is used by inserting the tip of the bottle into the nasal cavity and one short press on the dispenser.

When starting flu or ARVI apply one dose in both nasal passages three times a day for 5 days (the total daily dose should not be more than 500,000 IU).

For warning ARVI or flu (in contact with infected people) and after hypothermia, it is recommended to adhere to the following regimen of taking the drug: one dose in both nasal passages twice a day for 6-7 days.

Instructions for using nasal spray.

• remove the protective cap;
• When using for the first time, press the dispenser repeatedly until a small stream appears;
• Before use, place the bottle in a vertical position;
• administer the drug with a single short pressure on the dispenser in turn in both nasal passages;
• After use, close the protective cap.

To prevent the spread of infection, use the bottle strictly individually.

Overdose

If a large number of suppositories are accidentally administered simultaneously (in doses exceeding those prescribed), it is necessary to stop using the drug for one day, then you can resume treatment according to the prescribed regimen.

There are no data on cases of overdose with Genferon Light spray.

Interaction

Presence vitamins C And E enhance the effect of interferon components and slow down its denaturation when the drug is administered into the rectum.

Terms of sale

Genferon Light suppositories in Russia are sold with a prescription, but nasal spray can be bought without a prescription. In Ukraine, these drugs are sold strictly by prescription.

Storage conditions

It is recommended to store the drug out of the reach of children, in a dry and dark place in the temperature range of 2-8°C.

Best before date

special instructions

Genferon Light does not affect the reaction and ability to perform actions that require increased attention (driving a car, equipment, etc.).

Analogues

Analogue of Genferon Light spray form is .

Analogues of Genferon Light candle shape are , antiviral and antifungal drugs significantly increases the effectiveness of therapy.

Genferon Light during pregnancy

The use of Genferon Light “nasal spray” during pregnancy is possible at all stages, and reviews of its use are generally favorable.

The safety of the use of suppositories has been proven only in pregnant women with a period of 13-40 weeks, while in women in earlier stages of pregnancy there is no data on the safety of use. In each clinical case, the issue of using Genferon Light is decided separately by the attending physician.

The drug "Genferon" has immunostimulating, antioxidant, antiviral, immunomodulating, antimicrobial, membrane-stabilizing and anti-inflammatory properties.

If earlier the doctor prescribed flu in children, today the drug "Genferon" has become popular. Looking at the list of diseases that are treated with Genferon suppositories, many parents wonder why the doctor prescribed this drug, because the instructions indicate that they are genital herpes, chlamydia, vaginal candidiasis, ueraplasmosis, bacterial vaginosis, vulvovaginitis, trichomoniasis , urethritis, cervicitis, balanitis, prostatitis and the like. Let's figure it out.

"Genferon" (candles for children). Instructions

Children under seven years of age are prescribed the drug "Genferon Light" with a dosage of 125,000 units. "Genferon 125000" - candles, instructions for which will be presented below.

The human component of the Genferon product fights bacterial and viral infections, taurine accelerates recovery by improving metabolism. For children, the drug "Genferon" is prescribed as an additional remedy in the fight against ARVI and influenza.

Apply rectally or enter vaginally.

Children are prescribed the drug for five days, twice a day, one suppository rectally. Sometimes the treatment period can be increased by the doctor to 10 days.

The drug "Genferon" can cause dizziness, skin rash, increased sweating, itching, and loss of appetite.

"Genferon" - suppositories for them, however, reports that the product can also be used by adults, in particular, pregnant women. In general, it is well tolerated by patients.

The drug "Genferon Light" is suppositories for children, the safety and effectiveness of which have been proven by clinical studies. This drug is stored at a temperature of 2-8 degrees Celsius, out of the reach of children. The drug is available only with a doctor's prescription.

"Genferon" (suppositories for children) instructions for use

The drug is allowed to be used by children with diseases of the urogenital tract of an infectious-inflammatory nature, diseases of viral etiology.

The drug is used vaginally and rectally. Depending on the age of the child, a certain dosage of the drug and duration of treatment are prescribed. Children under seven years of age are prescribed Genferon Light suppositories at a dosage of 150,000 units. For adults and children over seven years of age, the doctor prescribes the drug at a dose of 250,000 units.

For infectious and inflammatory diseases of the urogenital tract, small patients are prescribed to use suppositories rectally twice a day. For viral diseases, rectal administration of the drug, one suppository twice a day, is also prescribed. For chronic viral diseases, a ten-day course of treatment is recommended for a sick child, 1 suppository, again 2 times a day.

To date, no life-threatening, severe adverse events have been observed. If you experience chills, headache, fever, joint pain, fatigue, sweating, or loss of appetite while using the drug, you should consult a doctor. Perhaps your dose will be reduced or the drug will be discontinued altogether.

The drug should be used with great caution in autoimmune and allergic diseases.

The drug "Genferon Light" is used in conjunction with fungicidal, antibacterial and antiviral drugs.

No cases of overdose have been recorded. If a large amount of the drug is administered per day, you should take a break for 24 hours.

Genferon Light suppositories are used rectally and administered vaginally. Drug dosage: 125,000 and 250,000 units.

The drug "Genferon" is a suppository for children, the instructions for which should be carefully studied.